CL2018001612A1 - Método de terapia fotodinámica (pdt) para el cáncer de vejiga - Google Patents
Método de terapia fotodinámica (pdt) para el cáncer de vejigaInfo
- Publication number
- CL2018001612A1 CL2018001612A1 CL2018001612A CL2018001612A CL2018001612A1 CL 2018001612 A1 CL2018001612 A1 CL 2018001612A1 CL 2018001612 A CL2018001612 A CL 2018001612A CL 2018001612 A CL2018001612 A CL 2018001612A CL 2018001612 A1 CL2018001612 A1 CL 2018001612A1
- Authority
- CL
- Chile
- Prior art keywords
- bladder cancer
- photodynamic therapy
- pdt
- therapy method
- composition
- Prior art date
Links
- 206010005003 Bladder cancer Diseases 0.000 title abstract 4
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 title abstract 4
- 201000005112 urinary bladder cancer Diseases 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000002428 photodynamic therapy Methods 0.000 title abstract 3
- ZGXJTSGNIOSYLO-UHFFFAOYSA-N 88755TAZ87 Chemical compound NCC(=O)CCC(O)=O ZGXJTSGNIOSYLO-UHFFFAOYSA-N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 108700001623 hexadecaisoleucinomycin Proteins 0.000 abstract 1
- CBCIHIVRDWLAME-UHFFFAOYSA-N hexanitrodiphenylamine Chemical compound [O-][N+](=O)C1=CC([N+](=O)[O-])=CC([N+]([O-])=O)=C1NC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O CBCIHIVRDWLAME-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/307—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the urinary organs, e.g. urethroscopes, cystoscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
- A61N5/0603—Apparatus for use inside the body for treatment of body cavities
- A61N2005/061—Bladder and/or urethra
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
- A61N2005/0663—Coloured light
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Surgery (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Radiation-Therapy Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
ESTA INVENCIÓN SE RELACIONA CON UN MÉTODO DE TERAPIA FOTODINÁMICA (PDT) PARA EL CÁNCER DE VEJIGA Y SU USO COMO UNA TERAPIA ADYUVANTE O NEOADYUVANTE EN EL TRATAMIENTO DEL CÁNCER DE VEJIGA. LA INVENCIÓN PROPORCIONA UNA COMPOSICIÓN QUE COMPRENDE ÉSTER DE HEXIL 5-ALA (HAL) O UNA SAL FARMACÉUTICAMENTE ACEPTABLE DE ESTE PARA EL USO EN UN MÉTODO DE TERAPIA FOTODINÁMICA PARA EL CÁNCER DE VEJIGA, EN DONDE DICHA COMPOSICIÓN SE INSTILA EN LA VEJIGA DE UN PACIENTE QUE NECESITA DICHO TRATAMIENTO Y EL INTERIOR DE DICHA VEJIGA SE EXPONE A LUZ AZUL QUE TIENE UNA VELOCIDAD DE FLUENCIA DE 1.5 A 12.5 MW/CM2 .
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15200938 | 2015-12-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2018001612A1 true CL2018001612A1 (es) | 2019-01-11 |
Family
ID=55066354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2018001612A CL2018001612A1 (es) | 2015-12-17 | 2018-06-14 | Método de terapia fotodinámica (pdt) para el cáncer de vejiga |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11235168B2 (es) |
| EP (1) | EP3389716B1 (es) |
| JP (1) | JP6995755B2 (es) |
| KR (1) | KR20180094986A (es) |
| CN (1) | CN108697800A (es) |
| AU (1) | AU2016372575B2 (es) |
| BR (1) | BR112018011965A2 (es) |
| CA (1) | CA3008552C (es) |
| CL (1) | CL2018001612A1 (es) |
| DK (1) | DK3389716T3 (es) |
| ES (1) | ES2910034T3 (es) |
| IL (1) | IL259925B (es) |
| PL (1) | PL3389716T3 (es) |
| RU (1) | RU2745194C2 (es) |
| SG (1) | SG11201805000RA (es) |
| WO (1) | WO2017103285A1 (es) |
| ZA (1) | ZA201804530B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201805000RA (en) * | 2015-12-17 | 2018-07-30 | Photocure Asa | Method of photodynamic therapy (pdt) for bladder cancer |
| CN110420326A (zh) * | 2019-09-17 | 2019-11-08 | 上海复旦张江生物医药股份有限公司 | 一种多替泊芬的应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0820432B1 (en) | 1995-03-10 | 2001-06-13 | PhotoCure ASA | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| US7530461B2 (en) * | 1995-03-10 | 2009-05-12 | Photocure Asa | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| US20050003154A1 (en) * | 2002-12-13 | 2005-01-06 | White Gary L. | Laminated building panels having preselected colors |
| GB0406917D0 (en) | 2004-03-26 | 2004-04-28 | Photocure Asa | Compounds |
| GB0700580D0 (en) | 2007-01-11 | 2007-02-21 | Photocure Asa | Use |
| GB0724279D0 (en) | 2007-12-12 | 2008-01-23 | Photocure Asa | Use |
| CN101891639A (zh) | 2009-05-20 | 2010-11-24 | 上海先导化学有限公司 | 一种制备5-氨基酮戊酸盐酸盐的方法 |
| JP2012529451A (ja) | 2009-06-11 | 2012-11-22 | フォトキュア エイエスエイ | ５−アミノレブリン酸を含む固体組成物 |
| WO2010142457A1 (en) | 2009-06-11 | 2010-12-16 | Photocure Asa | Semi-solid compositions and pharmaceutical products |
| RU2448745C2 (ru) * | 2010-05-31 | 2012-04-27 | Олег Феликсович Каган | Способ лечения поверхностного рака мочевого пузыря |
| US20150088001A1 (en) | 2011-12-19 | 2015-03-26 | Technical University Of Denmark | Illumination System for Endoscopic Applications |
| BR112015002390B1 (pt) | 2012-08-03 | 2020-03-24 | Photocure Asa | Derivados do ácido 5-aminolevulínico (5-ala), sua composição e seu uso como agentes fotossensibilizantes |
| GB201221123D0 (en) * | 2012-11-23 | 2013-01-09 | Photocure As | Device for photodynamic treatment |
| SG11201805000RA (en) * | 2015-12-17 | 2018-07-30 | Photocure Asa | Method of photodynamic therapy (pdt) for bladder cancer |
-
2016
- 2016-12-19 SG SG11201805000RA patent/SG11201805000RA/en unknown
- 2016-12-19 WO PCT/EP2016/081809 patent/WO2017103285A1/en active Application Filing
- 2016-12-19 US US16/063,142 patent/US11235168B2/en active Active
- 2016-12-19 AU AU2016372575A patent/AU2016372575B2/en active Active
- 2016-12-19 DK DK16810437.0T patent/DK3389716T3/da active
- 2016-12-19 KR KR1020187020005A patent/KR20180094986A/ko not_active Application Discontinuation
- 2016-12-19 RU RU2018123834A patent/RU2745194C2/ru active
- 2016-12-19 EP EP16810437.0A patent/EP3389716B1/en active Active
- 2016-12-19 PL PL16810437T patent/PL3389716T3/pl unknown
- 2016-12-19 JP JP2018532037A patent/JP6995755B2/ja active Active
- 2016-12-19 CN CN201680079638.6A patent/CN108697800A/zh active Pending
- 2016-12-19 ES ES16810437T patent/ES2910034T3/es active Active
- 2016-12-19 BR BR112018011965A patent/BR112018011965A2/pt not_active Application Discontinuation
- 2016-12-19 CA CA3008552A patent/CA3008552C/en active Active
-
2018
- 2018-06-10 IL IL259925A patent/IL259925B/en unknown
- 2018-06-14 CL CL2018001612A patent/CL2018001612A1/es unknown
- 2018-07-06 ZA ZA2018/04530A patent/ZA201804530B/en unknown
-
2022
- 2022-01-31 US US17/588,978 patent/US11980772B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| PL3389716T3 (pl) | 2022-06-20 |
| SG11201805000RA (en) | 2018-07-30 |
| DK3389716T3 (da) | 2022-04-11 |
| US11980772B2 (en) | 2024-05-14 |
| EP3389716B1 (en) | 2022-03-23 |
| ZA201804530B (en) | 2019-09-25 |
| IL259925B (en) | 2022-04-01 |
| IL259925A (en) | 2018-07-31 |
| JP2019501161A (ja) | 2019-01-17 |
| US20220152411A1 (en) | 2022-05-19 |
| WO2017103285A1 (en) | 2017-06-22 |
| CA3008552A1 (en) | 2017-06-22 |
| BR112018011965A2 (pt) | 2018-12-04 |
| US20190022404A1 (en) | 2019-01-24 |
| CN108697800A (zh) | 2018-10-23 |
| ES2910034T3 (es) | 2022-05-11 |
| RU2018123834A (ru) | 2020-01-17 |
| EP3389716A1 (en) | 2018-10-24 |
| KR20180094986A (ko) | 2018-08-24 |
| JP6995755B2 (ja) | 2022-01-17 |
| AU2016372575A1 (en) | 2018-07-12 |
| CA3008552C (en) | 2024-01-02 |
| US11235168B2 (en) | 2022-02-01 |
| AU2016372575B2 (en) | 2022-12-08 |
| RU2745194C2 (ru) | 2021-03-22 |
| RU2018123834A3 (es) | 2020-04-13 |
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