CN108567925A - A kind of Chinese medicine composition, preparation method and application for treating chicken coccidiasis - Google Patents

A kind of Chinese medicine composition, preparation method and application for treating chicken coccidiasis Download PDF

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CN108567925A
CN108567925A CN201810777712.2A CN201810777712A CN108567925A CN 108567925 A CN108567925 A CN 108567925A CN 201810777712 A CN201810777712 A CN 201810777712A CN 108567925 A CN108567925 A CN 108567925A
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weight
parts
chinese medicine
medicine composition
chicken coccidiasis
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刘扬北
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Zixing City Tai Kun Agriculture And Forestry Ecological Industry Co Ltd
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Zixing City Tai Kun Agriculture And Forestry Ecological Industry Co Ltd
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    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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Abstract

The present invention relates to a kind of Chinese medicine compositions, preparation method and application for treating chicken coccidiasis, the Chinese medicine composition of the treatment chicken coccidiasis is raw material by using Changshan, radix bupleuri, sweet wormwood, polygonum flaccidum, garden burnet, kuh-seng, 7 taste Chinese medicine of rhizoma imperatae and carries out suitable weight proportion, Changshan is monarch drug in a prescription in side, have the function of preventing malaria, rob phlegm, sweet wormwood, garden burnet are all ministerial drug, sweet wormwood has the function of antiprotozoan, heat-clearing, cool blood, garden burnet has cooling blood and hemostasis, the effect of removing toxic substances sore, radix bupleuri, polygonum flaccidum, kuh-seng are adjutant, and rhizoma imperatae is history medicine.According to the nature and flavor of each medicine, channel tropism, function, cure mainly and respectively open up its can monarch, minister, assistant, history, it supplements and complements each other, play the role of antiprotozoan, hemostasis, stop dysentery jointly, the Chinese medicine composition for the treatment chicken coccidiasis being finally prepared, treat chicken coccidiasis good effect, cure rate is high, of low cost, has no toxic side effect.

Description

A kind of Chinese medicine composition, preparation method and application for treating chicken coccidiasis
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition that treating chicken coccidiasis, its preparation side Method and application.
Background technology
Chicken coccidiasis is the parasitic disease that chicken is common and harm is extremely serious, is acute caused by one or more coccidias Popular parasitic disease.Economic loss caused by it is surprising.The chick of 10~30 ages in days or the young chicken of 35~60 ages in days Incidence and lethality may be up to 80%.The chick growth recovered is obstructed, and weightening is slow;Adult Chicken is not fallen ill generally, but is Carrier, weightening and egg laying performance reduce, and are the important pathogenies for propagating globidiosis.
Invention content
In order to solve the above-mentioned problems in the prior art, the present invention provide treatment chicken coccidiasis Chinese medicine composition and Preparation method.
The technical scheme is that:
The Chinese medicine composition of chicken coccidiasis is treated, raw material components include:
Changshan 20-40 parts by weight, radix bupleuri 5-25 parts by weight, sweet wormwood 10-30 parts by weight, polygonum flaccidum 5-25 parts by weight, garden burnet 10- 30 parts by weight, kuh-seng 5-25 parts by weight, rhizoma imperatae 5-15 parts by weight.
The Chinese medicine composition of the further preferred treatment chicken coccidiasis, raw material components include:
Changshan 25-35 parts by weight, radix bupleuri 10-20 parts by weight, sweet wormwood 15-25 parts by weight, polygonum flaccidum 10-20 parts by weight, garden burnet 15-25 parts by weight, kuh-seng 10-20 parts by weight, rhizoma imperatae 8-12 parts by weight.
The Chinese medicine composition of the further preferred treatment chicken coccidiasis, raw material components include:
30 parts by weight of Changshan, 15 parts by weight of radix bupleuri, 20 parts by weight of sweet wormwood, 15 parts by weight of polygonum flaccidum, 20 parts by weight of garden burnet, kuh-seng 15 parts by weight, 10 parts by weight of rhizoma imperatae.
The garden burnet is to process garden burnet.
The processing garden burnet is charred RADIX SANGUISORBAE.
A method of the Chinese medicine composition preparing the treatment chicken coccidiasis includes the following steps:
Changshan, radix bupleuri, sweet wormwood, polygonum flaccidum, garden burnet, kuh-seng, rhizoma imperatae are weighed respectively, after being separately dried, crushing, be sieved, Each raw material fine powder is obtained, after each raw material fine powder is sufficiently mixed, obtains mixed powder, the as described treatment chicken coccidiasis Chinese medicine composition.
The temperature for carrying out the drying is 60-90 DEG C, and the time for carrying out the drying is 1-6h.
The temperature for carrying out the drying is 75 DEG C, and the time for carrying out the drying is 4h.
The grain size of each raw material fine powder is 300-500 mesh.
A kind of feed for treating chicken coccidiasis includes the Chinese medicine composition of the treatment chicken coccidiasis.
To facilitate the understanding of the present invention, now in the present invention bulk pharmaceutical chemicals and drug effect be further elaborated.
Changshan:It is bitter, pungent, it is cold in nature.Preventing malaria robs phlegm.
Radix bupleuri:Acrid flavour, hardship, cold nature.In inducing diaphoresis, soothing liver-qi stagnation, yang invigorating, preventing malaria of bringing down a fever.
Sweet wormwood:It is bitter, pungent, it is cold in nature.Antiprotozoan, heat-clearing, cool blood.
Polygonum flaccidum:Acrid flavour, it is warm-natured.Expelling wind and removing dampness, removing blood stasis and analgesics, removing toxicity for detumescence, desinsection are antipruritic.
Garden burnet:Bitter, acid, puckery, cold nature.Cooling blood and hemostasis, removing toxic substances sore.
Charred RADIX SANGUISORBAE:Bitter, acid, puckery, cold nature.Cooling blood and hemostasis, removing toxic substances sore.For having blood in stool, hemorrhoid blood, bloody flux, uterine bleeding, water Burning hot wound, carbuncle sore tumefacting virus.
Kuh-seng:Bitter, it is cold in nature.Heat-clearing and damp-drying drug, desinsection, diuresis.For hot dysentery, have blood in stool.
Rhizoma imperatae:It is sweet in flavor, it is cold in nature.Cooling blood and hemostasis, reducing fever and causing diuresis.It spits blood for blood-head, bleeding from five sense organs or subcutaneous tissue, hematuria etc..
Beneficial effects of the present invention are:
It is of the present invention treatment chicken coccidiasis Chinese medicine composition, by using Changshan, radix bupleuri, sweet wormwood, polygonum flaccidum, garden burnet, Kuh-seng, 7 taste Chinese medicine of rhizoma imperatae are raw material and carry out suitable weight proportion, and Changshan is monarch drug in a prescription in side, with preventing malaria, robs phlegm Effect, sweet wormwood, garden burnet are all ministerial drug, and sweet wormwood has the function of that there is cooling blood and hemostasis, removing toxic substances to hold back for antiprotozoan, heat-clearing, cool blood, garden burnet The effect of sore, radix bupleuri, polygonum flaccidum, kuh-seng are adjutant, and rhizoma imperatae is history medicine.According to the nature and flavor of each medicine, channel tropism, function, cure mainly and each Zhan Qineng and energy monarch, minister, assistant, history, supplement and complement each other, play the role of antiprotozoan, hemostasis, stop dysentery jointly, be finally prepared The Chinese medicine composition of chicken coccidiasis is treated, treats chicken coccidiasis good effect, cure rate is high, of low cost, has no toxic side effect.
Specific implementation mode
Below by specific embodiment, the invention will be further described.
Embodiment 1
The present embodiment provides the Chinese medicine composition for the treatment of chicken coccidiasis, raw material components include:
Changshan 20g, radix bupleuri 5g, sweet wormwood 10g, polygonum flaccidum 5g, garden burnet 10g, kuh-seng 5g, rhizoma imperatae 5g.
Further, a kind of method for the Chinese medicine composition preparing the treatment chicken coccidiasis is provided, is included the following steps:
Changshan, radix bupleuri, sweet wormwood, polygonum flaccidum, garden burnet, kuh-seng, rhizoma imperatae are weighed respectively, each raw material is dry respectively at 60 DEG C After dry 6h, crushing, sieving, it is that each raw material fine powder of 300 purposes obtains after being sufficiently mixed each raw material fine powder to obtain grain size Mixed powder, the Chinese medicine composition of the as described treatment chicken coccidiasis.
Embodiment 2
The present embodiment provides the Chinese medicine composition for the treatment of chicken coccidiasis, raw material components include:
Changshan 40g, radix bupleuri 25g, sweet wormwood 30g, polygonum flaccidum 25g, garden burnet 30g, kuh-seng 25g, rhizoma imperatae 15g.
Further, a kind of method for the Chinese medicine composition preparing the treatment chicken coccidiasis is provided, is included the following steps:
Changshan, radix bupleuri, sweet wormwood, polygonum flaccidum, garden burnet, kuh-seng, rhizoma imperatae are weighed respectively, each raw material is dry respectively at 90 DEG C After dry 1h, crushing, sieving, it is that each raw material fine powder of 500 purposes obtains after being sufficiently mixed each raw material fine powder to obtain grain size Mixed powder, the Chinese medicine composition of the as described treatment chicken coccidiasis.
Embodiment 3
The present embodiment provides the Chinese medicine composition for the treatment of chicken coccidiasis, raw material components include:
Changshan 25g, radix bupleuri 10g, sweet wormwood 15g, polygonum flaccidum 10g, garden burnet 15g, kuh-seng 10g, rhizoma imperatae 8g.
Further, a kind of method for the Chinese medicine composition preparing the treatment chicken coccidiasis is provided, is included the following steps:
Changshan, radix bupleuri, sweet wormwood, polygonum flaccidum, garden burnet, kuh-seng, rhizoma imperatae are weighed respectively, each raw material is dry respectively at 80 DEG C After dry 3h, crushing, sieving, it is that each raw material fine powder of 500 purposes obtains after being sufficiently mixed each raw material fine powder to obtain grain size Mixed powder, the Chinese medicine composition of the as described treatment chicken coccidiasis.
Embodiment 4
The present embodiment provides the Chinese medicine composition for the treatment of chicken coccidiasis, raw material components include:
Changshan 35g, radix bupleuri 20g, sweet wormwood 25g, polygonum flaccidum 20g, charred RADIX SANGUISORBAE 25g, kuh-seng 20g, rhizoma imperatae 12g.
Further, a kind of method for the Chinese medicine composition preparing the treatment chicken coccidiasis is provided, is included the following steps:
Changshan, radix bupleuri, sweet wormwood, polygonum flaccidum, charred RADIX SANGUISORBAE, kuh-seng, rhizoma imperatae are weighed respectively, by each raw material respectively at 80 DEG C After dry 3h, crushing, sieving, it is that each raw material fine powder of 500 purposes obtains after being sufficiently mixed each raw material fine powder to obtain grain size To mixed powder, the Chinese medicine composition of the as described treatment chicken coccidiasis.
Embodiment 5
The present embodiment provides the Chinese medicine composition for the treatment of chicken coccidiasis, raw material components include:
Changshan 30g, radix bupleuri 15g, sweet wormwood 20g, polygonum flaccidum 15g, charred RADIX SANGUISORBAE 20g, kuh-seng 15g, rhizoma imperatae 10g.
Further, a kind of method for the Chinese medicine composition preparing the treatment chicken coccidiasis is provided, is included the following steps:
Changshan, radix bupleuri, sweet wormwood, polygonum flaccidum, charred RADIX SANGUISORBAE, kuh-seng, rhizoma imperatae are weighed respectively, by each raw material respectively at 75 DEG C After dry 4h, crushing, sieving, it is that each raw material fine powder of 400 purposes obtains after being sufficiently mixed each raw material fine powder to obtain grain size To mixed powder, the Chinese medicine composition of the as described treatment chicken coccidiasis.
Test example
The effect of the anti-Eimeria species of Chinese medicine composition for the treatment of chicken coccidiasis of the present invention is further studied by experiment, Specific testing program is as follows:
The good 1 week old broiler chicks of upgrowth situation 200 are randomly selected, treatment group A, treatment group B, treatment group are randomly divided into C, control group is infected, blank control group has 5 groups, every group 40 altogether, wherein treatment group A, treatment group B, treatment group C and infection pair According to a group difference seeded with pure kind E. pubescens Msxim 50000, blank control group is not inoculated with.
Treatment group A:3 traditional Chinese powder medicines of embodiment+basal diet (add 3 Chinese medicine of 0.5g embodiments in per kilogram basal diet Powder)
Treatment group B:4 traditional Chinese powder medicines of embodiment+basal diet (add 4 Chinese medicine of 0.5g embodiments in per kilogram basal diet Powder)
Treatment group C:5 traditional Chinese powder medicines of embodiment+basal diet (add 5 Chinese medicine of 0.5g embodiments in per kilogram basal diet Powder)
Infect control group:Basal diet
Blank control group:Basal diet
It is raised to 4 week old according to the above feeding method, observes the diet and excrement situation of each group chicken daily, the 28th age in days claims Weight is catched and killed, and the effect that the method for the present invention treats chicken coccidiasis is evaluated by anticoccidial index (ACI).
Anticoccidial index (ACI)=(body weight increase rate+survival rate) ﹣ (pathological changes value+oocyst value).
Drug effect criterion is:
ACI is less than 120, weak curative effect;ACI is 120-180, and curative effect is good;ACI is more than 180, and curative effect is excellent.
Specific test data is as shown in the table:
The Chinese medicine composition anticoccidial index (ACI) of 3-5 of embodiment of the present invention treatment chicken coccidiasis is respectively 196.7, 196.2,198.2, it is all higher than 180, anticoccidial drugs effect is determined as excellent, and 5 effect of embodiment is best.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.

Claims (10)

1. a kind of Chinese medicine composition for treating chicken coccidiasis, which is characterized in that raw material components include:
Changshan 20-40 parts by weight, radix bupleuri 5-25 parts by weight, sweet wormwood 10-30 parts by weight, polygonum flaccidum 5-25 parts by weight, garden burnet 10-30 weights Measure part, kuh-seng 5-25 parts by weight, rhizoma imperatae 5-15 parts by weight.
2. the Chinese medicine composition for the treatment of chicken coccidiasis according to claim 1, which is characterized in that raw material components include:
Changshan 25-35 parts by weight, radix bupleuri 10-20 parts by weight, sweet wormwood 15-25 parts by weight, polygonum flaccidum 10-20 parts by weight, garden burnet 15-25 Parts by weight, kuh-seng 10-20 parts by weight, rhizoma imperatae 8-12 parts by weight.
3. the Chinese medicine composition for the treatment of chicken coccidiasis according to claim 1, which is characterized in that raw material components include:
30 parts by weight of Changshan, 15 parts by weight of radix bupleuri, 20 parts by weight of sweet wormwood, 15 parts by weight of polygonum flaccidum, 20 parts by weight of garden burnet, 15 weight of kuh-seng Measure part, 10 parts by weight of rhizoma imperatae.
4. treating the Chinese medicine composition of chicken coccidiasis according to claim 1-3 any one of them, which is characterized in that the garden burnet To process garden burnet.
5. the Chinese medicine composition for the treatment of chicken coccidiasis according to claim 4, which is characterized in that the processing garden burnet is ground Elm charcoal.
6. a kind of method for the Chinese medicine composition preparing claim 1-5 any one of them treatment chicken coccidiasis, feature exist In including the following steps:
Changshan, radix bupleuri, sweet wormwood, polygonum flaccidum, garden burnet, kuh-seng, rhizoma imperatae are weighed respectively, after being separately dried, crushing, be sieved, are obtained Each raw material fine powder after being sufficiently mixed each raw material fine powder, obtains mixed powder, the Chinese medicine of the as described treatment chicken coccidiasis Composition.
7. the method for the Chinese medicine composition according to claim 6 for preparing treatment chicken coccidiasis, which is characterized in that carry out institute It is 60-90 DEG C to state dry temperature, and the time for carrying out the drying is 1-6h.
8. the method for the Chinese medicine composition according to claim 7 for preparing treatment chicken coccidiasis, which is characterized in that carry out institute It is 75 DEG C to state dry temperature, and the time for carrying out the drying is 4h.
9. the method for the Chinese medicine composition according to claim 6 for preparing treatment chicken coccidiasis, which is characterized in that described each The grain size of raw material fine powder is 300-500 mesh.
10. a kind of feed for treating chicken coccidiasis, which is characterized in that including any one of the claim 1-5 treatment Eimeria species The Chinese medicine composition of disease.
CN201810777712.2A 2018-07-16 2018-07-16 A kind of Chinese medicine composition, preparation method and application for treating chicken coccidiasis Pending CN108567925A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1907358A (en) * 2006-08-22 2007-02-07 天津生机集团有限公司 Pharmaceutical composition for preventing and treating avian coccidiosis and its preparing method
CN101007126A (en) * 2007-01-23 2007-08-01 天津生机集团有限公司 Drug for preventing or treating parasites of avian and its preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1907358A (en) * 2006-08-22 2007-02-07 天津生机集团有限公司 Pharmaceutical composition for preventing and treating avian coccidiosis and its preparing method
CN101007126A (en) * 2007-01-23 2007-08-01 天津生机集团有限公司 Drug for preventing or treating parasites of avian and its preparation method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘庆长: "中西兽药联合治疗鸡球虫病", 《福建畜牧兽医》 *
谌澄光: "中草药防治鸡病初报", 《中兽医科技资料》 *

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