CN108513537A - 筛选分化干细胞的试剂的方法 - Google Patents

筛选分化干细胞的试剂的方法 Download PDF

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Publication number
CN108513537A
CN108513537A CN201680064972.4A CN201680064972A CN108513537A CN 108513537 A CN108513537 A CN 108513537A CN 201680064972 A CN201680064972 A CN 201680064972A CN 108513537 A CN108513537 A CN 108513537A
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cancer
stem cells
nme7
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C·巴姆达德
S·莫
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Minerva Biotechnologies Corp
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Minerva Biotechnologies Corp
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Priority to CN202110344230.XA priority Critical patent/CN113527289A/zh
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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CN201680064972.4A 2015-09-23 2016-09-23 筛选分化干细胞的试剂的方法 Pending CN108513537A (zh)

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US201562222713P 2015-09-23 2015-09-23
US62/222,713 2015-09-23
PCT/US2016/053571 WO2017053886A2 (en) 2015-09-23 2016-09-23 Method of screening for agents for differentiating stem cells

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US (2) US11931347B2 (https=)
EP (1) EP3352566A4 (https=)
JP (2) JP2019515643A (https=)
CN (2) CN108513537A (https=)
AU (2) AU2016326718B2 (https=)
CA (1) CA2999503A1 (https=)
IL (3) IL258314B (https=)
WO (1) WO2017053886A2 (https=)

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CN115521306A (zh) * 2022-09-26 2022-12-27 贵州大学 一种1,2,3,4-四氢-β-咔啉衍生物及其制备方法和应用
CN115594675A (zh) * 2022-11-02 2023-01-13 西安医学院（Cn） 一种β-卡巴林-肉桂酸骨架衍生物及制备方法和用途

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EP3519816A4 (en) 2016-09-29 2020-05-06 The Regents of the University of California CONNECTIONS FOR INCREASING NEURONAL PLASTICITY
EP3600451B1 (en) * 2017-03-29 2025-12-24 Minerva Biotechnologies Corporation Agents for differentiating stem cells and treating cancer
CN107892690A (zh) * 2017-11-30 2018-04-10 江苏杏睿生物科技有限公司 Fascaplysin的衍生物及制备方法与用途
WO2019126357A1 (en) * 2017-12-19 2019-06-27 Minerva Biotechnologies Corporation Agents for treating cancer and methods for identifying said agents
CN107880040A (zh) * 2017-12-22 2018-04-06 中国药科大学 一种四氢β－咔啉类衍生物及其制备方法与用途
KR102946120B1 (ko) 2019-02-27 2026-03-30 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 뇌 장애를 치료하기 위한 아제피노-인돌 및 다른 헤테로사이클
CA3183682A1 (en) 2020-06-26 2021-12-30 Minerva Biotechnologies Corporation Anti-nme antibody and method of treating cancer or cancer metastasis
US12104170B2 (en) 2020-06-26 2024-10-01 Minerva Biotechnologies Corporation Methods for deriving dopaminergic neurons from pluripotent stem cells
IL313455A (en) 2021-12-15 2024-08-01 Delix Therapeutics Inc Phenoxy and benzyloxy modified psychroplastogens and their uses
CN119317447A (zh) 2022-04-12 2025-01-14 米纳瓦生物技术公司 抗可变muc1*抗体及其用途

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