CN108498408B

CN108498408B - Whitening essence

Info

Publication number: CN108498408B
Application number: CN201810595839.2A
Authority: CN
Inventors: 刘瑞学; 冷群英
Original assignee: Guangdong Bawei Biotechnology Co ltd
Current assignee: Guangdong Bawei Biotechnology Co ltd
Priority date: 2018-06-11
Filing date: 2018-06-11
Publication date: 2021-03-16
Anticipated expiration: 2038-06-11
Also published as: CN108498408A

Abstract

The invention discloses a whitening essence, and aims to provide a whitening essence which has no side effect, can effectively inhibit melanin formation, and has good moisturizing, anti-wrinkle and freckle removing effects. Mainly comprises the following components of 0.16-1.25 percent of pH regulator, 0.01-0.03 percent of chelating agent, 3-9 percent of humectant, 0.2-1.3 percent of preservative, 0.05-0.2 percent of antioxidant, 3-8 percent of spot removing agent, 0.11-0.6 percent of emulsifier, 0.4-1.5 percent of emollient, 0.25-0.8 percent of thickening agent, 1-8 percent of plant extract active composition and a proper amount of water; belongs to the technical field of cosmetics.

Description

Whitening essence

Technical Field

The invention discloses an essence, in particular to a whitening essence, and belongs to the technical field of skin care products.

Background

Asian women generally belong to yellowish flesh, but traditional culture advocates more white skin, so the whitening essence becomes a necessary maintenance product for various manufacturers and many young women.

The principle of the whitening product is mainly to inhibit tyrosinase of a human body to control the formation of melanin. The types of whitening cosmetics on the market are increasing, but many cosmetics contain heavy metal components, and when the cosmetics are used, a certain whitening effect can be achieved in a short time, but certain dependence is generated on the skin, and once the cosmetics are not used, the skin becomes dark and grows a lot of spots. The use of cosmetics containing heavy metals also causes certain side effects on the skin.

Skin aging is mainly in the form of natural aging (i.e., intrinsic aging) and photoaging (i.e., extrinsic aging), which is mainly caused by body genetic factors, is limited to the whole body, and is apparently characterized by wrinkles and sagging, and pigmentation, etc. Photoaging is mainly skin aging caused by accumulation of ultraviolet damage, is a result of combined action of natural aging and ultraviolet irradiation, is limited to exposed parts of skin, and is mainly characterized by rough and lusterless skin, deepening walking stability, deepening pigmentation, worsening skin microcirculation, deformation of elastic tissues, reduction of the skin expression of scavenging capacity, synthesis capacity and immunity of collagen and elastin, thinning of dermis, easy occurrence of allergic inflammation and the like.

Chinese herbal medicines have been used for treating and caring various skin diseases for thousands of years. In recent years, due to concerns about toxicity and irritation of chemical cosmetics, more and more scientific researchers tend to search for safe and efficient whitening active substances from natural plants.

Disclosure of Invention

In order to solve the problems, the invention provides the whitening essence which has no side effect, can effectively inhibit melanin formation and has good moisturizing, anti-wrinkle and freckle removing effects.

Therefore, the technical scheme provided by the invention is as follows:

a whitening essence mainly comprises 0.16-1.25% of pH regulator, 0.01-0.03% of chelating agent, 3-9% of humectant, 0.2-1.3% of preservative, 0.05-0.2% of antioxidant, 3-8% of freckle removing agent, 0.11-0.6% of emulsifier, 0.4-1.5% of emollient, 0.25-0.8% of thickener, 1-8% of plant extract active composition and a proper amount of water.

The plant extraction conditioning composition comprises the following main components in percentage by mass of the total whitening essence: 0.1-0.5% of malva sylvestris extract, 0.1-1% of corydalis edulis flower/leaf extract, 0.1-0.8% of rumex acetosa extract, 0.1-1% of Lepidium meyenii bud extract and 0.05-0.3% of Tilia latifolia extract.

Further, in the whitening essence, the pH regulator comprises the following components in percentage by mass of the total weight of the whitening essence: 0.06 to 0.25 percent of triethanolamine; 0.1 to 1 percent of citric acid; the antioxidant is tocopherol acetate; the preservative comprises the following components in percentage by mass of the total mass of the whitening essence: 0.1 to 1 percent of phenoxyethanol// ethylhexylglycerin, 0.1 to 0.3 percent of methylparaben,

further, in the whitening essence, the humectant is butanediol.

Further, the freckle removing agent comprises the following components in percentage by mass of the total mass of the whitening essence: 2-5% of tranexamic acid and 1-3% of nicotinamide.

Further, in the whitening essence, the emulsifier comprises the following components in percentage by mass of the total mass of the whitening essence: 0.01-0.1% of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside and 0.1-0.5% of C20-22 alcohol/C20-22 alcohol phosphate.

Further, the skin-whitening essence comprises the following components in percentage by mass: 0.3-1% of cyclopentasiloxane/cyclohexasiloxane and 0.1-0.5% of glycerol tri (ethylhexanoate).

Further, in the whitening essence, the thickening agent comprises the following components in percentage by mass of the total mass of the whitening essence: 0.1-0.3% of acryloyl dimethyl ammonium taurate/VP copolymer, 0.05-0.2% of xanthan gum and 0.1-0.3% of carbomer.

Furthermore, the whitening essence comprises 0.2-0.9% of achillea extract, 0.3-3% of dipsacus root extract and 0.05-0.5% of medicinal veronica extract by taking the total weight of the whitening essence as 100%.

Further, the whitening essence comprises 0.01-0.06% of solubilizer and 0.005-0.2% of aromatic.

Compared with the prior art, the technical scheme provided by the invention has the following technical advantages:

1. according to the technical scheme provided by the application, the malva sylvestris extract, the corydalis edulis flower/leaf extract, the rumex acetosa extract, the copaizoon herb bud extract and the tilia latifolia extract are subjected to mutual synergistic action, the generation of collagen and hyaluronic acid is promoted by inhibiting cathepsins such as tyrosinase, two metalloproteinases, caspase, elastase and the like, the proliferation effect on epidermal keratinocytes is realized, and the functions of restoring the elasticity and balance of skin fiber tissues and accelerating the metabolism of the skin cells are realized, so that the skin color is balanced, and color spots and freckles are lightened; moisten dry skin, make skin smooth, but have elasticity; and the skin whitening cream can slow down cell proliferation, resist aging, achieve the effects of whitening and brightening the skin instantly and for a long time, keep the skin moisture and improve the skin compactness.

2. The technical scheme provided by the application is combined with the milfoil extract, the dipsacus root extract and the medicinal veronica extract for synergism, and has the effects of cutin removal, oxidation resistance, antibiosis and skin cleaning, so that the overall formula of the product has excellent effects of smoothing, moisturizing, purifying, brightening and regenerating.

3. The technical scheme provided by the formula has the effects of calming and astringing the skin, can pacify the irritated skin, treat the damaged skin, reduce the redness of the skin, has no side effect, and has good whitening, moisturizing and anti-wrinkle effects.

Detailed Description

The claims of the present invention are described in further detail below with reference to specific embodiments.

Arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside, C20-22 alcohol/C20-22 alcohol phosphate were purchased from Yukikai corporation, Inc.

Example 1

The invention provides whitening essence which specifically comprises the following components:

example 2

The invention provides another whitening essence which specifically comprises the following components:

example 3

example 4

example 5

example 6

the preparation method of the whitening essence in any one of embodiments 1 to 6 specifically comprises the following steps:

1. mixing the phase A raw materials, heating to 80 +/-3 ℃, stirring to dissolve uniformly, and keeping the temperature for later use; mixing the raw materials of the E phase, heating to 65 +/-3 ℃ for dissolving, and cooling to 50 +/-3 ℃ for later use;

2. mixing the phase B raw materials, adding the mixture into a vacuum emulsifying pot, stirring and heating the mixture to 85 +/-3 ℃, adding the phase C raw materials, homogenizing the mixture until the material body is uniform and has no particles, keeping the temperature and stirring the mixture for 10 +/-5 minutes, adding the prefabricated phase A, homogenizing the mixture, keeping the temperature and stirring the mixture for 20 +/-5 minutes, and cooling the mixture;

3. cooling to 60 +/-3 ℃, adding the pre-dissolved D-phase raw material, uniformly stirring, and continuously cooling;

4. cooling to 50 +/-3 ℃, adding the prefabricated E and the pre-dissolved F phase raw material, and uniformly stirring;

5. cooling to 45 + -3 deg.C, sequentially adding G and premixed H phase (if not, adding no), and stirring.

Experimental example 1

The capacitance method is used for measuring the moisture content of the human skin stratum corneum, and is based on the obvious difference of dielectric constants of water and other substances, the capacitance values of the measured skin are different according to the moisture content of the skin stratum corneum, and the parameters can represent the moisture content of the skin.

120 subjects of 20-45 years old were randomly selected and divided into 6 groups of 20 subjects. The whitening essence liquids of examples 1 to 6 were used by 6 groups of test subjects once in the morning and evening for 30 days.

The moisture content of the skin was measured on day 0 and day 30 using a skin moisture tester Corneometer CM825, and the moisture content of the skin before and after the use of the whitening essence was evaluated.

The moisturizing efficacy test results are shown in table 1.

TABLE 1 moisture content variation of skin

As can be seen from the experimental results in table 1, the skin moisture content can be significantly increased after the whitening essence of examples 1 to 6 of the present invention is used for 30 days, which indicates that the whitening essence of the present invention has a good moisturizing effect.

Experimental example 2

Principle of experiment

The change in skin color can be measured using a skin complexion measuring instrument. The currently widely adopted measuring method for quantifying skin color is to measure the change of skin color by a colorimetric system (Lab colorimetric system) specified by the International Commission on illumination (CIE), and the method has accurate quantification, can reflect the multidimensional change of a skin color space, and ensures that the skin color is quantified more reliably. The test indexes are the MI value of the skin melanin content (the higher the measured value is, the higher the melanin content in the skin is), the L value of the skin whiteness/brightness and the ITA degree (the L value indicates that L is white balance, the larger the value is, the more white the color is, the ITA degree value is the individual type angle of the skin, and the larger the ITA degree value is, the brighter the skin). Therefore, the whitening effect of the cosmetic can be judged by measuring the melanin content of the skin stratum corneum and the skin chromaticity.

△MI＝T_n-T₀(ii) a In the formula T_nThe time-varying value of the tested area; t is₀Is the initial value of the tested area.

△L*＝T_n-T₀(ii) a In the formula T_nThe time-varying value of the tested area; t is₀Is the initial value of the tested area.

△ITA°＝T_n-T₀(ii) a In the formula T_nThe time-varying value of the tested area; t is₀Is the initial value of the tested area.

Laboratory apparatus

Multifunctional skin test system (MPA580, CK, germany);

skin color difference test probe and (CL400, CK, germany);

skin red melanin tester and test probe (Mexameter MX18, CK, germany).

Experimental methods

120 adults with dull facial skin color are screened, the adults are randomly divided into 6 groups, 20 adults in each group are used as test persons, the facial skin is subjected to melanin and color difference data acquisition, analysis and test before the samples are tried, and the data are used as skin background values. The sample was used once in the morning and at night for 4 weeks. Data collection was performed at week 1, week 2, and week 4, respectively. The change of skin whiteness (brightness) and skin melanin content before and after the application of the cosmetics to the subject was evaluated, thereby determining the whitening effect of the cosmetics.

Experimental samples: the whitening essence of example 1 to example 6.

The results are shown in tables 2 to 4.

TABLE 2 results of MI value test of skin melanin before and after using the product

As can be seen from table 2, the MI values of skin melanin are all reduced after the whitening essence of the present invention is used, which indicates that the whitening essence of the present invention has the effect of reducing skin melanin.

TABLE 3 statistical results of skin brightness L before and after application of the product

As can be seen from table 3, within 4 weeks of the test period, after the test subjects used the whitening essence of the present invention, the skin brightness L value was increased, indicating that the whitening essence of the present invention has the effect of improving skin whiteness.

TABLE 4 statistical results of ITA DEG values of skin brightness before and after application of the product

As can be seen from table 4, the skin brightness ITA ° value of the subject increased after the subject used the whitening essence of the present invention within 4 weeks of the test period, which indicates that the whitening essence of the present invention has the effect of improving skin brightness.

The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.

Claims

1. The whitening essence is characterized by comprising 0.16-1.25% of pH regulator, 0.01-0.03% of chelating agent, 3-9% of humectant, 0.2-1.3% of preservative, 0.05-0.2% of antioxidant, 3-8% of freckle removing agent, 0.11-0.6% of emulsifier, 0.4-1.5% of emollient, 0.25-0.8% of thickening agent, 1-8% of plant extraction active composition, 0.01-0.06% of solubilizer, 0.005-0.2% of aromatic and a proper amount of water;

the plant extract active composition comprises the following components in percentage by mass of the total whitening essence: 0.1-0.5% of malva sylvestris extract, 0.1-1% of corydalis flower/leaf extract, 0.1-0.8% of rumex acetosa extract, 0.1-1% of lepidium meyenii bud extract, 0.05-0.3% of tilia latifolia extract, 0.2-0.9% of milfoil extract, 0.3-3% of dipsacus root extract and 0.05-0.5% of medicinal veronica extract;

the freckle removing agent comprises the following components in percentage by mass of the total mass of the whitening essence: 2-5% of tranexamic acid and 1-3% of nicotinamide.

2. The whitening essence of claim 1, wherein the pH regulator comprises the following components in percentage by mass of the total whitening essence: 0.06 to 0.25 percent of triethanolamine; 0.1 to 1 percent of citric acid; the antioxidant is tocopherol acetate; the preservative comprises the following components in percentage by mass of the total mass of the whitening essence: 0.1 to 1 percent of phenoxyethanol/ethylhexyl glycerin and 0.1 to 0.3 percent of methyl hydroxybenzoate.

3. The whitening essence of claim 1, wherein the humectant is butylene glycol.

4. The whitening essence according to claim 1, wherein the emulsifier comprises the following components in percentage by mass of the total whitening essence: 0.01-0.1% of arachidyl alcohol/behenyl alcohol/arachidyl alcohol glucoside and 0.1-0.5% of C20-22 alcohol/C20-22 alcohol phosphate.

5. The whitening essence of claim 1, wherein the emollient comprises the following components in percentage by mass of the total mass of the whitening essence: 0.3-1% of cyclopentasiloxane/cyclohexasiloxane and 0.1-0.5% of glycerol tri (ethyl hexanoate).

6. The whitening essence according to claim 1, wherein the thickener comprises the following components in percentage by mass: 0.1-0.3% of acryloyl dimethyl ammonium taurate/VP copolymer, 0.05-0.2% of xanthan gum and 0.1-0.3% of carbomer.