CN108452133A - A kind of snake oil ointment of wind-expelling pain-stopping and preparation method thereof - Google Patents
A kind of snake oil ointment of wind-expelling pain-stopping and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a kind of snake oil ointments of wind-expelling pain-stopping and preparation method thereof, are related to the snake oil ointment technical field of wind-expelling pain-stopping, which includes following ingredient：Mix snake oil, dragon's blood, radix aconiti agrestis, safflower, lopseed, thickener, wherein mixing snake oil is mixed by pallas pit viper oil, zaocys dhumnade oil and Bungarus multicinctus oil；The present invention is using the mixing snake oil with wind-expelling pain-stopping as primary raw material, and it adds with wind-dispelling, analgesic, Chinese herbal medicine promoting blood circulation and removing blood stasis use different preparation methods for different raw materials, finally, it adds mixing thickener homogeneous again to mix, preparation method is simple, not only has and greatly retains pharmacological property, curative effect is improved, and has the function of reducing manufacturing cost.
Description
Technical field
The invention belongs to wind-expelling pain-stopping pharmaceutical techniques fields, and in particular to a kind of snake oil ointment of wind-expelling pain-stopping and its preparation side
Method.
Background technology
Snake oil is that the fat of snake section animal is extracted through refining, and applying for snake oil has long history in China.Snake oil
In based on unsaturated fatty acid, there is stronger affine permeability to be easily absorbed by the skin to mucocutaneous.Civil common snake oil
Pernio, chap, eczema and scald are treated, research is found in snake oil containing there are many essential trace elements of the human bodys.These yuan
Element participates in the composition of internal enzyme, and required for the activity of enzyme.Adjusting and the control work to organism metabolism are played by enzyme system
With their synthesis to nucleic acid, protein, cell proliferation, immunologic process etc. has direct or indirect effect, while snake oil also has
There is antalgic and inflammation relieving, snake oil is absorbed through skin and gastrointestinal tract, and nonirritant and pathergy is safe and non-toxic.
Rheumatism be one group of infringement joint, bone, muscle, blood vessel and in relation to soft tissue or knot hoof tissue based on disease,
Main clinical manifestation is arthralgia or whole-body muscular pain.Shown by the pharmacological research to snake：Dinodon rufozonatum snake, pallas pit viper, five steps
Snake, zaocys dhumnade, tiger spot cloubrid and Bungarus multicinctus have the function of wind-damp dispelling, dredging collateral and analgesic.Mostly it is at present to use to the research of snake oil
Skin care and beauty product are gone, it is less to the drug research of wind-damp dispelling class, even without special cooperation prescription.
Invention content
According to the above-mentioned deficiencies of the prior art, the technical problem to be solved by the present invention is to propose that a kind of formula is reasonably dispelled
The snake oil ointment and preparation method thereof of wind analgesic, in order to solve the above-mentioned technical problem, the technical solution adopted by the present invention is：
A kind of snake oil ointment of wind-expelling pain-stopping, the snake oil ointment include following ingredient：Mix snake oil, dragon's blood, radix aconiti agrestis, safranine
Flower, lopseed, thickener, wherein mixing snake oil is mixed by pallas pit viper oil, zaocys dhumnade oil and Bungarus multicinctus oil.
Preferably, the snake oil ointment includes following parts by weight ingredient：Mix 40-55 parts of snake oil, 13-20 parts of dragon's blood, radix aconiti agrestis
8-15 parts, 12-17 parts of safflower is 3-10 parts deep, 2.5-5.5 parts of thickener.Wherein, it is 1 that mixing snake oil, which is mass ratio,:0.5-
1:Pallas pit viper oil, zaocys dhumnade oil and the Bungarus multicinctus oil mixture of 0.8-1.3.
Preferably, the snake oil ointment includes following parts by weight ingredient：50 parts of snake oil, 15 parts of dragon's blood are mixed, 12 parts of radix aconiti agrestis is hidden
14.5 parts of safflower, deep 7.5 parts, 4 parts of thickener.Wherein, it is 1 that mixing snake oil, which is mass ratio,:0.7:1.1 pallas pit viper oil, the black tip
Snake oil and Bungarus multicinctus oil mixture.
Preferably, the thickener is glycerine, propylene glycol, coconut oil, at least two in sorbitol or monoglyceride.
A kind of preparation method of the snake oil ointment of wind-expelling pain-stopping, preparation process are as follows：
1) preparation of snake oil is mixed：Pallas pit viper, zaocys dhumnade and Bungarus multicinctus fat are weighed respectively, and 3 kinds of snake fat are ground respectively
10-15min is crushed, absolute ethyl alcohol is then separately added into the snake fat of crushing, it is 1 to keep solid-liquid ratio:4-6, and in ultrasound
Heating is lower to extract snake oil, and then snake oil is carried out to vacuum distillation extraction 2-3 times respectively, obtain independent snake oil, then weigh 3 by formula
Kind snake oil is uniformly mixed, and obtains mixing snake oil；
2) radix aconiti agrestis, safflower and lopseed are dried under vacuum to water content not higher than 5% for 45-50 DEG C in temperature, then will
Dry radix aconiti agrestis, safflower and lopseed are ground into the particle that grain size is 1-2mm, and then hybrid particles are placed in absolute ethyl alcohol
1-1.5h is impregnated, then the hybrid particles of immersion are extracted under ultrasound using steam distillation, extract liquor is used
Water distillation extractor repeats extraction 2 times, obtains liquid A；
3) dragon's blood is subjected to high speed ball milling, it is 300-400 mesh to be milled to grain size, then by dragon blood powder, liquid A, mixing snake
Oil and thickener are uniformly mixed, and carry out homogenization, obtain the snake oil ointment of wind-expelling pain-stopping.
Preferably, the rotating speed of the grinding is 1200-1500r/min, and the effect of physical treatment, shearing force increases cell wall
Destructive rate, improve the recovery rate of grease.
Preferably, the ultrasonic power of the Ultrasonic Heating is 300-400w, and the temperature of frequency 30-40Hz, heating are 90-
100 DEG C, ultrasonic cavitation and efficiency act on, and are conducive to the precipitation of grease, promote the extraction yield of snake oil.
Preferably, the rotating speed of the high speed ball milling is 1800-2000r/min.
Preferably, the condition of the homogeneous is pressure 4-7MPa, and time 5-10min promotes the stability of compound lard.
Compared with prior art, beneficial effects of the present invention：
1. then the present invention uses ultrasound with pallas pit viper, the fat first progress crushed material reason pretreatment of zaocys dhumnade and Bungarus multicinctus
The method that extraction heat and vacuum distillation are combined carries out snake oil extraction to the mixing snake fat of crushing, mixing snake oil is prepared,
The destructive rate that the shearing force in physics pretreatment is conducive to increase adipocyte wall is crushed, the recovery rate of grease is improved, then surpasses
The cavitation and efficiency of sound act on, and more further improve the extraction yield of snake oil, the extraction process of entire snake oil, not only
Recovery rate is high, and efficient, green pollution-free.
2. the present invention is added using the mixing snake oil with wind-expelling pain-stopping as primary raw material with wind-dispelling, analgesic, promoting blood circulationization
The Chinese herbal medicine of the stasis of blood uses different preparation methods for different raw materials, finally adds mixing thickener homogeneous again and is blended in one
It rises, preparation method is simple, not only has and greatly retains pharmacological property, improves curative effect, and with the work for reducing manufacturing cost
With.
Specific implementation mode
It below by the description to embodiment, is described in further detail, to help those skilled in the art to this hair
Bright inventive concept, technical solution have more complete, accurate and deep understanding.
Embodiment 1
The snake oil ointment of wind-expelling pain-stopping includes following parts by weight ingredient in the present embodiment：Mix 50 parts of snake oil, 15 parts of dragon's blood, grass
12 parts of crow, 14.5 parts of safflower, deep 7.5 parts, 4 parts of thickener.Wherein, it is 1 that mixing snake oil, which is mass ratio,:0.7:1.1 Pallas pit viper
Snake oil, zaocys dhumnade oil and Bungarus multicinctus oil mixture, thickener are that mass ratio is 1:0.5:0.5 glycerine, propylene glycol, coconut oil
Mixture.
The preparation method of the snake oil ointment of wind-expelling pain-stopping, preparation process are as follows：
1) preparation of snake oil is mixed：Pallas pit viper, zaocys dhumnade and Bungarus multicinctus fat are weighed respectively, and 3 kinds of snake fat are respectively according to such as
Lower step carries out producing for snake oil, and snake fat is placed in grinder, 15min is ground at rotating speed 1300r/min, then
Absolute ethyl alcohol is added into the snake fat of crushing, it is 1 to keep solid-liquid ratio:4, then mixed liquor is placed in Vltrasonic device, and
At power 350w, the ultrasound of frequency 35Hz, 90 DEG C are heated to, hot ultrasonic extraction snake oil is carried out to mixed liquor, it then will extraction
The snake oil taken is placed on vacuum distillation apparatus, carries out vacuum distillation extraction 2 times, three kinds of snake oils take the method to prepare, and are subtracting
It presses in distillation process, under vacuum conditions, temperature is 85 DEG C, obtains pure snake oil, then weighing 3 kinds of mass ratioes by formula is for distillation
1:0.7:1.1 pallas pit viper oil, zaocys dhumnade oil and Bungarus multicinctus oil, is uniformly mixed, obtains mixing snake oil；
2) it is 12 portions of radix aconiti agrestis to weigh parts by weight, and 14.5 parts of safflowers and 7.5 lopseeds are dried under vacuum in temperature 50 C and contain
Water is 4%, and then dry radix aconiti agrestis, safflower and lopseed are placed in pulverizer, and co-grinding is at that grain size is 1mm
Hybrid particles, are then placed in absolute ethyl alcohol and impregnate 1.5h by grain, after filtering, by the hybrid particles of immersion in power 400w, frequency
It under rate 40Hz ultrasounds, is extracted using steam distillation, in wet distillation process, when vapour pressure reaches saturation state
Starting to collect extract liquor, preparation process Chinese medicine is always maintained at saturation state, when the liquid of extraction is free of oil droplet, stops extraction,
Extract liquor is repeated into extraction 2 times using Water distillation extractor, obtains liquid A；
3) dragon's blood that parts by weight are 15 parts is weighed by formula, dragon's blood is placed in high speed ball mill, in rotating speed 1900r/min
Lower progress high speed ball milling, it is 350 mesh to be milled to grain size, then by dragon blood powder, liquid A, the mixing snake oil of 50 parts of parts by weight and 4 parts
By mass ratio be 1:0.5:The thickener of 0.5 glycerine, propylene glycol, the mixing of coconut oil is uniformly mixed, and is put into
Homogenization 10min is carried out in pressure 5Mpa in matter machine, obtains the snake oil ointment of wind-expelling pain-stopping.
Embodiment 2
The present embodiment is with embodiment 1, the difference is that the snake oil ointment of wind-expelling pain-stopping includes 40 parts of snake oil of mixing in the present embodiment,
13 parts of dragon's blood, 8 parts of radix aconiti agrestis, 12 parts of safflower, deep 3 parts, 2.5 parts of thickener.Wherein, it is 1 that mixing snake oil, which is mass ratio,:0.5:
0.8 pallas pit viper oil, zaocys dhumnade oil and Bungarus multicinctus oil mixture.
Embodiment 3
The present embodiment with embodiment 1, unlike in the present embodiment the snake oil ointment of wind-expelling pain-stopping include following parts by weight at
Point：55 parts of snake oil of mixing, 20 parts of dragon's blood, 15 parts of radix aconiti agrestis, 17 parts of safflower, deep 10 parts, 5.5 parts of thickener.Wherein, snake is mixed
Oil is that mass ratio is 1:1:1.3 pallas pit viper oil, zaocys dhumnade oil and Bungarus multicinctus oil mixture, thickener are that mass ratio is 1:0.5:
0.5：The mixture of 0.5 propylene glycol, coconut oil, sorbitol and monoglyceride.
Embodiment 4
The present embodiment is with embodiment 1, the difference is that ultrasonic in the preparation method of the snake oil ointment of wind-expelling pain-stopping in the present embodiment
Power is 300w, and the condition of frequency 30Hz, homogeneous are pressure 7MPa, time 5min.
Case efficacy analysis：
1, it tests
It chooses rheumatoid-arthritis 100 and is classified as 3 groups of observation group and control group 1 as the analysis object of this research
Group, each 25, average every group of the man 14 of observation group, female 11；Average age be (35.8 scholar 3.1) year, course of disease 2-3.
Control group man 12, female 13；Average age be (33.7 ± 4.1) year, course of disease 2-3.The equal medicine-less allergy history of patient.Two groups
Gender, age and the course of disease of patient compares, and no significant difference (P ＞ 0.05) has comparativity.
2, method
Observation group：The snake oil ointment of wind-expelling pain-stopping prepared by embodiment 1-3 is given respectively by observation group, is uniformly applied with ointment every time
It is put on affected part, and is massaged into whole absorptions, 3 times a day, 7 days courses for the treatment of, control group is given commercially available ointment and treated, controlled
During treatment, keeps affected part warm, do not suffer from cold.
3, observation index
It is effective:Affected part pain disappears, and irregular shiver of body also disappears；Effectively：Patient's ill symptoms make moderate progress；Nothing
Effect：Patient's ill symptoms do not improve or deteriorate.Total effective rate=obvious effective rate+effective percentage.
4, data are all made of 22.0 softwares of SPSS and are handled.Measurement data withIt indicates, is examined using t, counted
Number data is with number of cases (n), and percentage (%) indicates, using x2It examines, is that difference is statistically significant with P ＜ 0.05.
Two groups of patient outcomes are as follows：
It is statistically significant (P ＜ 0.05) through data difference between two groups of Research statistics.
The present invention is exemplarily described above in conjunction with specific embodiment, it is clear that the present invention implements not by upper
The limitation of mode is stated, if the improvement of the various unsubstantialities of inventive concept and technical scheme of the present invention progress is used, or
It is not improved by the present invention design and technical solution directly apply to other occasions, protection scope of the present invention it
It is interior.Protection scope of the present invention should be determined by the scope of protection defined in the claims.
Claims (9)
1. a kind of snake oil ointment of wind-expelling pain-stopping, which is characterized in that the snake oil ointment includes following ingredient：Mix snake oil, dragon's blood, grass
Crow, safflower, lopseed, thickener, wherein mixing snake oil is mixed by pallas pit viper oil, zaocys dhumnade oil and Bungarus multicinctus oil.
2. the snake oil ointment of wind-expelling pain-stopping according to claim 1, which is characterized in that the snake oil ointment includes following parts by weight
Ingredient：Mix 40-55 parts of snake oil, 13-20 parts of dragon's blood, 8-15 parts of radix aconiti agrestis, 12-17 parts of safflower, 3-10 parts deep, thickener
2.5-5.5 part.Wherein, it is 1 that mixing snake oil, which is mass ratio,:0.5-1:Pallas pit viper oil, zaocys dhumnade oil and the Bungarus multicinctus oil of 0.8-1.3 mixes
Close object.
3. the snake oil ointment of wind-expelling pain-stopping according to claim 1, which is characterized in that the snake oil ointment includes following parts by weight
Ingredient：50 parts of snake oil of mixing, 15 parts of dragon's blood, 12 parts of radix aconiti agrestis, 14.5 parts of safflower, deep 7.5 parts, 4 parts of thickener.Wherein, it mixes
Conjunction snake oil is that mass ratio is 1:0.7:1.1 pallas pit viper oil, zaocys dhumnade oil and Bungarus multicinctus oil mixture.
4. the snake oil ointment of wind-expelling pain-stopping according to claim 1, which is characterized in that the thickener be glycerine, propylene glycol,
At least two in coconut oil, sorbitol or monoglyceride.
5. a kind of preparation method of the snake oil ointment of any wind-expelling pain-stoppings of claim 1-4, which is characterized in that preparation process
It is as follows：
1) preparation of snake oil is mixed：Pallas pit viper, zaocys dhumnade and Bungarus multicinctus fat are weighed respectively, and 3 kinds of snake fat are ground respectively
Then 10-15min is separately added into absolute ethyl alcohol into the snake fat of crushing, it is 1 to keep solid-liquid ratio:4-6, and in Ultrasonic Heating
Then snake oil is carried out vacuum distillation extraction 2-3 times, obtains independent snake oil, then weigh 3 kinds of snakes by formula by lower extraction snake oil respectively
Oil is uniformly mixed, and obtains mixing snake oil；
2) radix aconiti agrestis, safflower and lopseed are dried under vacuum to water content not higher than 5% for 45-50 DEG C in temperature, then will dried
Radix aconiti agrestis, safflower and lopseed are ground into the particle that grain size is 1-2mm, then hybrid particles are placed in absolute ethyl alcohol and are impregnated
Then 1-1.5h is extracted the hybrid particles of immersion under ultrasound using steam distillation, by extract liquor using distillation
Extraction repeats extraction 2 times, obtains liquid A；
3) by dragon's blood carry out high speed ball milling, be milled to grain size be 300-400 mesh, then by dragon blood powder, liquid A, mixing snake oil and
Thickener is uniformly mixed, and carries out homogenization, obtains the snake oil ointment of wind-expelling pain-stopping.
6. the preparation method of the snake oil ointment of wind-expelling pain-stopping according to claim 5, which is characterized in that the rotating speed of the grinding
For 1200-1500r/min.
7. the preparation method of the snake oil ointment of wind-expelling pain-stopping according to claim 5, which is characterized in that the Ultrasonic Heating
Ultrasonic power is 300-400w, and the temperature of frequency 30-40Hz, heating are 90-100 DEG C.
8. the preparation method of the snake oil ointment of wind-expelling pain-stopping according to claim 5, which is characterized in that the high speed ball milling
Rotating speed is 1800-2000r/min.
9. the preparation method of the snake oil ointment of wind-expelling pain-stopping according to claim 5, which is characterized in that the condition of the homogeneous
For pressure 4-7MPa, time 5-10min.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110898094A (en) * | 2019-12-27 | 2020-03-24 | 灵山县龙璇蛇业有限公司 | Snake oil cream and preparation method thereof |
| CN112618693A (en) * | 2021-01-15 | 2021-04-09 | 苏哲文 | Conditioning oil for treating diabetic foot gangrene |
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Application publication date: 20180828 |