CN109010187A - A kind of face cream and preparation method thereof for treating acne - Google Patents
A kind of face cream and preparation method thereof for treating acne Download PDFInfo
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Abstract
The invention discloses a kind of face creams and preparation method thereof for treating acne.The face cream consists of the following mass percentage components: blood circulation promoting pill Aqueous extracts 0.5-1.0%, root bark of tree peony Aqueous extracts 0.5-1.0%, panax japonicus Aqueous extracts 0.4-0.8%, Rosa Damascana 100-500ppm, bee venom 10-50ppm, hyaluronic acid 0.5-1.0%；60 0.9-2% of polysorbate, glycerol 4-7%, propylene glycol 2-5%, octyl dodecanol xyloside 0.5-0.8%, PEG-30 dimerization hydroxy stearic acid ester 1-2%, lauric alcohol-caprylate 15-25%, Sodium Polyacrylate 1-2%, sorbic acid 0.1-0.2%, methyl hydroxybenzoate 0.1-0.2%；Surplus is deionized water.The preparation method is as follows: heating is used as water phase after polysorbate 60, propylene glycol, glycerol, Sodium Polyacrylate, deionized water are mixed；As oily phase after being heated after octyl dodecanol xyloside, PEG-30 dimerization hydroxy stearic acid ester, lauric alcohol-caprylate are mixed；The oil phase is added to the aqueous phase obtains mixed phase；By remaining ingredient be added mixed phase in, it is agitated uniformly after sterilize to obtain the final product.Prepared face cream safety gets well and has good acne treatment effect.
Description
Technical field
The invention belongs to biological chemical fields, and in particular to a kind of preparation process and side for treating the face cream of acne
Method, be it is a not only can replenishing water and preserving moisture, but also can effectively antibacterial anti-inflammatory, improve acne, promote skin healing face cream product.
Background technique
Acne is also known as acne, whelk, is a kind of chronic inflammatory skin, is apt to occur in teenager, disease incidence is up to
70%-87%, Etiological are that the level of androgen especially testosterone in descendant's body that adolesces increases rapidly, promote sebum
Gland develops and produces a large amount of sebum.The dyskeratosis of pilosebaceous duct causes catheter blockage, sebum discharge barrier simultaneously
Hinder, forms horn plug, that is, micro mist thorn.The microorganisms such as propionibacterium acnes mass propagation and the lipase generated decomposition sebum in hair follicle
Free fatty acid, while chemotactic inflammatory cell and medium are generated, finally induces and aggravates inflammatory reaction.Acne involves position in hair
Capsule sebaceous glands, is often accompanied by seborrhea, is typically distributed about face, chest and back, can behave as a variety of different degrees of skin lesion types,
Including acne, papule, tubercle, warts, tumour etc..It also easily forms that pigmentation, pore be coarse or even scar etc. leaves illness, it is right
The psychology of patient and life cause serious influence.
Most of face cream common at present or the production and preparation that face cream is carried out using industrial chemicals, although portioned product
Certain therapeutic effect can be played, but there may be certain irritation and side effects, and since its is palliative, nothing
Method is used for a long time and reaches a preferable treatment and lasting effects.
Also part face cream uses the extracting solution of natural component as main component, but its major part uses raw material straight
The mode for connecing crushing or grinding is handled, and such processing mode will lead to effective component and be unable to fully utilize.In addition to this,
No effective antibacterial bacteriostatic ingredient carries out compatibility, and therapeutic effect is relatively limited.
Summary of the invention
In view of the shortcomings of the prior art, the present invention provides a kind of face cream product and preparation method thereof for treating acne.It should
Product compensates for the defect of existing product, while replenishing water and preserving moisture can effective antibacterial anti-inflammatory, improve acne, scar of dispelling, promote
Skin healing, mitigates body and the psychological burden of patient, and integrated artistic is simple, convenient for large-scale production.
Technical solution provided by the invention is as follows:
It is a kind of for treating the face cream of acne, be made of the raw material and other auxiliary materials of following mass percent.
Wherein, raw material: blood circulation promoting pill Aqueous extracts 0.5-1.0%, root bark of tree peony Aqueous extracts 0.5-1.0%, panax japonicus extracting solution
0.4-0.8%, Rosa Damascana 100-500ppm, bee venom 10-50ppm, hyaluronic acid 0.5-1.0%；
Other auxiliary materials: 60 0.9-2% of polysorbate, glycerol 4-7%, propylene glycol 2-5%, octyl dodecanol xyloside
0.5-0.8%, PEG-30 dimerization hydroxy stearic acid ester 1-2%, lauric alcohol-caprylate 15-25%, Sodium Polyacrylate 1-2%, mountain
Pears acid 0.1-0.2%, methyl hydroxybenzoate 0.1-0.2%；Surplus is deionized water.
Above-mentioned every 10mL blood circulation promoting pill Aqueous extracts are prepared by the following steps:
S1, blood circulation promoting pill herb 100g is taken, smashes it through 40-80 mesh, obtain blood circulation promoting pill powder；
S2, into blood circulation promoting pill powder, addition 400mL deionized water is heated to 100 DEG C and maintains 3h, and filtrate is obtained by filtration；The
Secondary addition 300mL deionized water is heated to 100 DEG C and maintains 2h, and filtrate is obtained by filtration；
S3, will twice filtrate merge after filtrate is concentrated by evaporation under conditions of 60 DEG C, 0.08-0.1MPa it is standby to 10mL
With.
Above-mentioned every 10mL root bark of tree peony Aqueous extracts are prepared by the following steps:
S1, root bark of tree peony 100g is taken, smashes it through 80-100 mesh, obtain root bark of tree peony powder；
S2, into root bark of tree peony powder, addition 400mL deionized water is heated to 100 DEG C and maintains 3h, and filtrate is obtained by filtration；Second
Secondary addition 300mL deionized water is heated to 100 DEG C and maintains 2h, and filtrate is obtained by filtration；
S3, will twice filtrate merge after filtrate is concentrated by evaporation under conditions of 60 DEG C, 0.08-0.1MPa it is standby to 10mL
With.
Above-mentioned every 10mL panax japonicus Aqueous extracts are prepared by the following steps:
S1, the panax japonicus rhizome for taking 100g, smash it through 40-80 mesh, obtain panax japonicus powder；
S2, it 400mL deionized water is added into panax japonicus powder is submerged, with Ultrasonic cell smash by powder
Ultrasonic treatment 2 times, 30min/ times, merges extracting solution twice；
S3, extracting solution twice is subjected to decompression suction filtration under conditions of 0.08-0.1MPa, filtrate obtained, into filter residue
The deionized water of 400mL is added, is heated to reflux 3 hours, decompression suction filtration is carried out at 0.08-0.1MPa, obtains filtrate, by institute
There is gained filtrate to merge；
S4, gained filtrate is concentrated by evaporation under conditions of 60 DEG C, 0.08-0.1MPa it is spare to 10mL.
Another object of the present invention is to provide the preparation methods of above-mentioned face cream, comprising the following steps:
1) it is heated after mixing polysorbate 60, propylene glycol, glycerol, Sodium Polyacrylate, deionized water, after mixing evenly
As water phase；
2) it is heated after mixing octyl dodecanol xyloside, PEG-30 dimerization hydroxy stearic acid ester, lauric alcohol-caprylate,
After mixing evenly as oily phase；
3) during the oil phase is added to the aqueous phase, mixed phase is obtained after lower stirring；
4) mixed phase is added in blood circulation promoting pill water extract, root bark of tree peony water extract, Effect of Panax Japonicus, Rosa Damascana and bee venom
In, add sorbic acid, methyl hydroxybenzoate, hyaluronic acid, it is agitated uniformly after after ultra high temperature short time sterilization processing packing to obtain the final product
To finished product face cream.
Above-mentioned steps 1) in heating temperature be 72-75 DEG C, mixing time 8-10min.
Above-mentioned steps 2) in heating temperature be 75-78 DEG C, mixing time 8-10min.
Above-mentioned steps 3) speed of agitator be 500-550r/min, mixing time 8-10min.
The raw materials used in the present invention and its characteristic are as follows:
Blood circulation promoting pill: this product is the herb of Lamiaceae plant blood circulation promoting pill.Major function are as follows: dampness removing is treating stranguria, it is clearing heat and detoxicating, dissipate the stasis of blood
Detumescence.With multiple efficacies such as antibacterial anti-inflammatory, heat clearing and blood circulation promotings.Bacteriostatic experiment shows that blood circulation promoting pill Aqueous extracts have propionibacterium acnes
There is stronger inhibiting effect, it is also inhibited to Staphylococcus aureus etc..
The root bark of tree peony: for ranunculaceae peony dry root skin.With clearing heat and cooling blood, activate blood circulation and disperse blood clots and other effects.Its decoction is to dysentery
The various pathogens such as Shigella, typhoid bacillus and pathogenic dermatophyte have inhibiting effect.Modern study, contained paeonol and
Glucosides constituents other than it have anti-inflammatory effect.
Panax japonicus: for the dry rhizome of Araliaceae panax japonicus, it is one kind of China's Chinese medicine, can heat-clearing solution
Heat, secretion replenishing and throat moistening.For removing blood stasis and acesodyne, hemostasis eliminating the phlegm.
Rosa Damascana: Rosa Damascana is that rose takes the filemot essential oil extracted in latter 24 hours, energy in the morning
The immune and nervous system of stimulation and landman, while helping to improve the secretion of endocrine gland, organ sclerosis is removed, is repaired thin
Born of the same parents.Rosa Damascana has antibacterial, anti-inflammatory, calmness, benefit body and other effects.Be applicable in all skin quality still its be it is mature dry or sensitive, appoint
What sensitive red and swollen and inflammation skin.Rosa Damascana has effect that is strong and shrinking capilary, there is splendid protection to aging skin
Effect.
Bee venom: a kind of transparency liquid with aromatic odor secreted out of for Apidae worker bee poison gland and accessory gland is stored in
In malicious capsule.With dispelling wind and eliminating dampness, the effect of analgesic.Bee venom is a kind of mixture of complicated component, and wherein moisture accounts for 80%-
88%, also containing several protein and peptide class, enzyme, histamine, acids, amino acid and microelement etc..Bee venom has anti-
Bacterium, it is anti-inflammatory, the effects of.It may also suppress inflammation, swelling.Stimulation of Pituitary Gland-adrenal system promotes the release of cortin, adjustment
Immune function.
Hyaluronic acid: being one of the main matrix ingredient of application on human skin epidermis and corium, physiological function be can make moisture into
Enter space between cells, and form protein gel in conjunction with protein, cell is sticked together, the cell metabolism brought into normal play is made
With playing and keep cell moisture, protect cell not by the infringement of pathogen, accelerate to restore skin histology, raising Wound healing is again
Raw ability, reduces scar.
The main component of face cream prepared by the present invention utilizes traditional Chinese medicine and pharmacy compatibility with strong points.Blood circulation promoting pill, bee venom are to drawing
The propionibacterium acnes for playing acne have stronger killing effect；The root bark of tree peony has clearing heat and cooling blood, activates blood circulation and disperses blood clots and other effects；Ring people
Ginseng has preferable activating microcirculation and removing stasis medicinal, scar of dispelling effect；Rosa Damascana not only has stronger killing effect to propionibacterium acnes, but also
With stronger permeability, the active constituent for being conducive to other materials effectively penetrates into skin, moreover it is possible to product be made to have virtue well
Fragrance；Hyaluronic acid has stronger replenishing water and preserving moisture effect.
Beneficial effects of the present invention:
1) present invention utilizes TCM treatment experience, and prepared face cream has antibacterial anti-inflammatory, heat clearing and blood circulation promoting, moisturizing profit
On the one hand the effect of skin, detumescence and promoting granulation effectively can inhibit pathogenic bacteria to grow, on the other hand can promote quickly being cured for the acne surface of a wound
It closes；
2) raw material is all made of traditional Chinese medicine ingredients extracting solution, and compatibility is suitable, and formula safety is mild, with strong points；
3) protection skin and moisture-keeping efficacy are had both.
Specific embodiment
The present invention is further described combined with specific embodiments below, and the contents of the present invention are completely without being limited thereto.
To avoid repeating, percentage composition refers both to mass percent in following embodiments, blood circulation promoting pill Aqueous extracts in embodiment,
Root bark of tree peony Aqueous extracts, panax japonicus Aqueous extracts preparation method be described collectively.
The preparation method of blood circulation promoting pill Aqueous extracts (by taking every 10mL concentrate as an example):
S1, blood circulation promoting pill herb 100g is taken, smashes it through 40 meshes, obtain blood circulation promoting pill powder；
S2, into blood circulation promoting pill powder, addition 400mL deionized water is heated to 100 DEG C and maintains 3h, and filtrate is obtained by filtration；The
Secondary addition 300mL deionized water is heated to 100 DEG C and maintains 2h, and filtrate is obtained by filtration.
S3, their crude extract is concentrated by evaporation under conditions of 60 DEG C, 0.08MPa it is spare to 10mL.
The preparation method of root bark of tree peony Aqueous extracts (by taking every 10mL concentrate as an example):
S1, root bark of tree peony 100g is taken, smashes it through 80 meshes, obtain root bark of tree peony powder；
S2, into root bark of tree peony powder, addition 400mL deionized water is heated to 100 DEG C and maintains 3h, and filtrate is obtained by filtration；Second
Secondary addition 300mL deionized water is heated to 100 DEG C and maintains 2h, and filtrate is obtained by filtration.
S3, will twice filtrate merge after filtrate is concentrated by evaporation under conditions of 60 DEG C, 0.08MPa it is spare to 10mL.
The preparation method of panax japonicus Aqueous extracts (by taking every 10mL concentrate as an example):
S1, the panax japonicus rhizome for taking 100g, smash it through 60 meshes, obtain panax japonicus powder；
S2, it 400mL deionized water is added into panax japonicus powder is submerged, with Ultrasonic cell smash by powder
Ultrasonic treatment 2 times, 30min/ times, merges extracting solution twice；
S3, extracting solution twice is subjected to decompression suction filtration under conditions of 0.08MPa, obtains filtrate, is added into filter residue
The deionized water of 400mL is heated to reflux 3 hours, decompression suction filtration is carried out at 0.08MPa, obtains filtrate, all gained are filtered
Liquid merges；
S4, by gained filtrate, be concentrated by evaporation under conditions of 60 DEG C, 0.08MPa through rotary evaporator spare to 10mL.
Embodiment 1
Composition of raw materials: blood circulation promoting pill Aqueous extracts 0.5%, root bark of tree peony Aqueous extracts 0.5%, panax japonicus Aqueous extracts 0.4%, rhodamine toner
Oily 100ppm, bee venom 10ppm, hyaluronic acid 0.5%；
Other materials formula: polysorbate 60 0.9%, glycerol 4%, propylene glycol 2%, octyl dodecanol xyloside
0.5%, PEG-30 dimerization hydroxy stearic acid ester 1%, lauric alcohol-caprylate 15%, Sodium Polyacrylate 1%, sorbic acid 0.1%,
Methyl hydroxybenzoate 0.1%；Deionized water 73.5%.
Face cream the preparation method is as follows:
1) 72 are heated to after mixing polysorbate 60, propylene glycol, glycerol, Sodium Polyacrylate, deionized water in proportion
DEG C, it stirs evenly, mixing time 8min, as water phase；
2) after octyl dodecanol xyloside, PEG-30 dimerization hydroxy stearic acid ester, lauric alcohol-caprylate being mixed in proportion
75 DEG C are heated to, is stirred evenly, mixing time 8min, as oily phase；
3) during the oil phase is added to the aqueous phase, 8min is stirred at 500r/min and obtains mixed phase；
4) blood circulation promoting pill water extract, root bark of tree peony water extract, Effect of Panax Japonicus, Rosa Damascana and bee venom are proportionally added into mixed
It closes in phase, addition sorbic acid, methyl hydroxybenzoate, hyaluronic acid dispense after high-temperature short-time sterilization is handled after stirring evenly and obtain finished product
Face cream.
Embodiment 2
Composition of raw materials: blood circulation promoting pill Aqueous extracts 0.75%, root bark of tree peony Aqueous extracts 0.75%, panax japonicus Aqueous extracts 0.6%, rose
Essential oil 250ppm, bee venom 30ppm, hyaluronic acid 0.75%.
Other materials formula: polysorbate 60 1.45%, glycerol 5.5%, propylene glycol 3.5%, octyl dodecanol xylose
Glycosides 0.65%, PEG-30 dimerization hydroxy stearic acid ester 1.5%, lauric alcohol-caprylate 20%, Sodium Polyacrylate 1.5%, sorbic acid
0.15%, methyl hydroxybenzoate 0.15%；Deionized water 63.05%.
Face cream the preparation method is as follows:
1) add after mixing polysorbate 60, propylene glycol, glycerol, Sodium Polyacrylate, deionized water by mass percentage
Heat is stirred evenly to 73.5 DEG C, mixing time 9min, as water phase；
2) by mass percentage by octyl dodecanol xyloside, PEG-30 dimerization hydroxy stearic acid ester, lauric alcohol-caprylate
It is heated to 76.5 DEG C after mixing, stirs evenly, mixing time 9min, as oily phase；
3) during the oil phase is added to the aqueous phase, 9min is stirred at 525r/min and obtains mixed phase；
5) blood circulation promoting pill water extract, root bark of tree peony water extract, Effect of Panax Japonicus, Rosa Damascana and bee venom are proportionally added into mixed
It closes in phase, addition sorbic acid, methyl hydroxybenzoate, hyaluronic acid dispense after high-temperature short-time sterilization is handled after stirring evenly and obtain finished product
Face cream.
Embodiment 3
Composition of raw materials: blood circulation promoting pill Aqueous extracts 1.0%, root bark of tree peony Aqueous extracts 1.0%, panax japonicus Aqueous extracts 0.8%, rhodamine toner
Oily 500ppm, bee venom 50ppm, hyaluronic acid 1.0%.
Other materials formula: polysorbate 60 2%, glycerol 7%, propylene glycol 5%, octyl dodecanol xyloside
0.8%, PEG-30 dimerization hydroxy stearic acid ester 2%, lauric alcohol-caprylate 25%, Sodium Polyacrylate 2%, sorbic acid 0.2%,
Methyl hydroxybenzoate 0.2%；Deionized water 48%.
Face cream the preparation method is as follows:
1) add after mixing polysorbate 60, propylene glycol, glycerol, Sodium Polyacrylate, deionized water by mass percentage
Heat is stirred evenly to 75 DEG C, mixing time 10min, as water phase；
2) by mass percentage by octyl dodecanol xyloside, PEG-30 dimerization hydroxy stearic acid ester, lauric alcohol-caprylate
It is heated to 78 DEG C after mixing, stirs evenly, mixing time 10min, as oily phase；
3) during the oil phase is added to the aqueous phase, 10min is stirred at 550r/min and obtains mixed phase；
4) by blood circulation promoting pill water extract, root bark of tree peony water extract, Effect of Panax Japonicus, Rosa Damascana and bee venom by described in right 1
Ratio is added among the above, is eventually adding after sorbic acid, methyl hydroxybenzoate, hyaluronic acid stir evenly after high-temperature short-time sterilization is handled
Packing obtains finished product face cream.
Embodiment 4
Bacteriostatic experiment
(1) experimental strain: propionibacterium acnes (ATCC 6919)
(2) bacterium culture medium: sulphur glycollate culture medium
(3) experimental procedure: the bacteria suspension of propionibacterium acnes is prepared, then bacteria suspension is uniformly smeared and is inoculated in THIOGLYCOLLIC ACID
On salt culture medium double-layer plate, is then punched with the punch that diameter is 12mm, then 0.1g face cream is taken to be placed in hole respectively,
The distilled water of control group equivalent replaces, and is finally placed in insulating box incubator and cultivates 48h, surveys the antibacterial circle diameter of each plate,
Each sample does three Duplicate Samples, and average antibacterial circle diameter reaches 38mm, and control group does not have fungistatic effect, illustrates face cream to drawing
The main pathogenic bacteria propionibacterium acnes for playing acne have good inhibiting effect.
Embodiment 5
Face cream prepared by Examples 1 to 3 treats acne measure of merit: it is on probation through 100 face acnes aspirations, wherein male
Each 25 people of female, the age 15-35 years old.Volunteer is divided into two groups, and one group uses this face cream, and another group uses commercially available a certain treatment acne
Product compares.Application method are as follows: patient directly uses this product, each daily morning and evening to use once, after cleaning face, directly
Tested products are uniformly applied to acne part, adhere to the effect for examining face cream of the invention to treat acne using 10 days.Curative effect
Judgment criteria are as follows: recovery from illness: face acnes skin lesion healing, the healing surface of a wound are generated without acne scar, acne print；Effective: face acnes are reduced, or
Surface of a wound redness mitigates；Invalid: illness is unchanged or aggravation.As a result as shown in the table:
The result shows that: pair face cream prepared by the present invention is to the efficient substantially better than the face cream of comparison of acne treatment, i.e.,
There is preferable therapeutic effect in acne.
The foregoing is only a preferred embodiment of the present invention, but the scope of protection of the invention be not limited thereto,
Any modification that anyone skilled in the art is made in the technical scope disclosed by the present invention, equivalent replacement and
Improve etc., it should be included within the protection scope of invention.
Claims (8)
1. a kind of for treating the face cream of acne, which is characterized in that be made of the raw material and other auxiliary materials of following mass percent:
Wherein, raw material: blood circulation promoting pill Aqueous extracts 0.5-1.0%, root bark of tree peony Aqueous extracts 0.5-1.0%, panax japonicus Aqueous extracts 0.4-
0.8%, Rosa Damascana 100-500ppm, bee venom 10-50ppm, hyaluronic acid 0.5-1.0%；
Other auxiliary materials: 60 0.9-2% of polysorbate, glycerol 4-7%, propylene glycol 2-5%, octyl dodecanol xyloside 0.5-
0.8%, PEG-30 dimerization hydroxy stearic acid ester 1-2%, lauric alcohol-caprylate 15-25%, Sodium Polyacrylate 1-2%, sorbic acid
0.1-0.2%, methyl hydroxybenzoate 0.1-0.2%；
Surplus is deionized water.
2. face cream according to claim 1, which is characterized in that every 10mL blood circulation promoting pill Aqueous extracts are by following steps system
It is standby:
S1, blood circulation promoting pill herb 100g is taken, smashes it through 40-80 mesh, obtain blood circulation promoting pill powder；
S2, into blood circulation promoting pill powder, addition 400mL deionized water is heated to 100 DEG C and maintains 3h, and filtrate is obtained by filtration；Second
300mL deionized water is added to be heated to 100 DEG C and maintain 2h, filtrate is obtained by filtration；
S3, will twice filtrate merge after filtrate is concentrated by evaporation under conditions of 60 DEG C, 0.08-0.1MPa it is spare to 10mL.
3. face cream according to claim 1, which is characterized in that every 10mL root bark of tree peony Aqueous extracts are prepared by the following steps:
S1, root bark of tree peony 100g is taken, smashes it through 80-100 mesh, obtain root bark of tree peony powder；
S2, into root bark of tree peony powder, addition 400mL deionized water is heated to 100 DEG C and maintains 3h, and filtrate is obtained by filtration；Add for the second time
Enter 300mL deionized water to be heated to 100 DEG C and maintain 2h, filtrate is obtained by filtration；
S3, will twice filtrate merge after filtrate is concentrated by evaporation under conditions of 60 DEG C, 0.08-0.1MPa it is spare to 10mL.
4. face cream according to claim 1, which is characterized in that every 10mL panax japonicus Aqueous extracts are by following steps system
It is standby:
S1, the panax japonicus rhizome for taking 100g, smash it through 40-80 mesh, obtain panax japonicus powder；
S2, it 400mL deionized water is added into panax japonicus powder is submerged, with Ultrasonic cell smash by powder ultrasonic
Processing 2 times, 30min/ times, merges extracting solution twice；
S3, extracting solution twice is subjected to decompression suction filtration under conditions of 0.08-0.1MPa, obtains filtrate, is added into filter residue
The deionized water of 400mL is heated to reflux 3 hours, decompression suction filtration is carried out at 0.08-0.1MPa, obtains filtrate, by all institutes
Filtrate is obtained to merge；
S4, gained filtrate is concentrated by evaporation under conditions of 60 DEG C, 0.08-0.1MPa it is spare to 10mL.
5. a kind of preparation method of face cream described in claim 1, comprising the following steps:
1) it is heated after mixing polysorbate 60, propylene glycol, glycerol, Sodium Polyacrylate, deionized water, conduct after mixing evenly
Water phase；
2) it heats, stirs after mixing octyl dodecanol xyloside, PEG-30 dimerization hydroxy stearic acid ester, lauric alcohol-caprylate
As oily phase after uniformly；
3) during the oil phase is added to the aqueous phase, mixed phase is obtained after lower stirring；
4) blood circulation promoting pill water extract, root bark of tree peony water extract, Effect of Panax Japonicus, Rosa Damascana and bee venom are added in mixed phase, then
Be added sorbic acid, methyl hydroxybenzoate, hyaluronic acid, it is agitated uniformly after obtain finished product after ultra high temperature short time sterilization processing packing
Face cream.
6. preparation method according to claim 5, it is characterised in that: heating temperature is 72-75 DEG C in the step 1), is stirred
Mixing the time is 8-10min.
7. preparation method according to claim 5, it is characterised in that: heating temperature is 75-78 DEG C in the step 2), is stirred
Mixing the time is 8-10min.
8. preparation method according to claim 5, it is characterised in that: the step 3) speed of agitator is 500-550r/
Min, mixing time 8-10min.
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Cited By (1)
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| CN115252501A (en) * | 2022-08-27 | 2022-11-01 | 广州市博之越精细化工有限公司 | Acne-curing composition and preparation method and application thereof |
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Application publication date: 20181218 |