CN108452046A - A kind of pharmaceutical composition and preparation method thereof for treating goat taeniasis - Google Patents
A kind of pharmaceutical composition and preparation method thereof for treating goat taeniasis Download PDFInfo
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- CN108452046A CN108452046A CN201810713321.4A CN201810713321A CN108452046A CN 108452046 A CN108452046 A CN 108452046A CN 201810713321 A CN201810713321 A CN 201810713321A CN 108452046 A CN108452046 A CN 108452046A
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- taeniasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a kind of pharmaceutical composition and preparation method thereof for treating goat taeniasis, the pharmaceutical composition of the treatment goat taeniasis, by weight, including following raw material：16 20 parts of FRUCTUS CARPESII, 12 16 parts of pomegranate root skin, 10 14 parts of discadenoid cherry root, 12 16 parts of rhizome of cyrtomium, 10 14 parts of hawthorn, 0.1 0.3 parts of ivermectin, 0.1 0.3 parts of albendazole tablet.Preparation method is screening bulk pharmaceutical chemicals, is sampled by weight；Chinese medicine is added up into 68 times of water of quality, after boiling by intense fire, is cooked by slow fire 25 35min, decocting liquid of fetching water, 57 times of dosing material gross weight measures water to the dregs of a decoction again, after boiling by intense fire, is cooked by slow fire 20 30min, merges decocting liquid twice；Ivermectin, albendazole tablet are added in Chinese medicine decocting liquid, mixing after dissolving to obtain the final product.The present invention has the characteristics that rapid-action, good effect, has no toxic side effect.
Description
Technical field
The invention belongs to pharmaceutical technology fields, and in particular to a kind of pharmaceutical composition for treating goat taeniasis, simultaneously also
It is related to the preparation method of the pharmaceutical composition of the treatment goat taeniasis.
Background technology
Taenia ovis disease is also known as parasitosis and ruminates beast taeniasis, is by not Buddhist nun time tapeworm, the song palace tapeworm of Anoplocephalidae and without ovum
Yellow gland tapeworm colonizes in caused by small enteral, wherein most strong with not Buddhist nun time tapeworm pathogenicity, main harm lamb and calf can
Cause affected animal dead.Taeniasis is widely distributed in China, is in endemic conditions, metainfective symptom, due to infection intensity, age
Different, general Temperature changing is little, the course of disease is long, obviously becomes thin, has yellow-white nodal plate in diarrhea, row's loose stool, excrement, turn-take, grind one's teeth in sleep.
Low-grade infection or adult sheep infection when, general symptom unobvious, lamb infection and adult cattle and sheep severe infections when symptom it is apparent,
Digestive disorders are shown as, the nodal plate to fall off is often mixed in frequent abdominal pain, intestines distension gas and diarrhea, excrement, is day by day become thin, anaemia, is had
Appearance spasm, the nervous symptoms such as turn-take.The initial stage lamb of disease also has appetite reduction, and drinks the phenomenon that be increased.The latter stage of disease,
Affected animal does not rise with crouching because of failure, eats dishes without rice or wine to chew, spit out white foams, and slow in reacting or disappearance is finally died because cachexia dies of exhaustion.
Reinforcement feeding management at present, preventative expelling parasite are required for putting into more human and material resources, slightly relax, Jiu Huizao
At undesirable effect, currently, using antibiosis extract for treating merely, it is also easy to produce drug resistance, carrys out extreme difficulties to treatment zone.Chinese medicine price is low
Honest and clean, toxic side effect is small, no drug resistance, free from environmental pollution, moreover it is possible to achieve the effect that treating both manifestation and root cause of disease.
Invention content
The purpose of the present invention is to provide the medicines of a kind of rapid-action, good effect, the treatment goat taeniasis having no toxic side effect
Compositions.
Another object of the present invention is to provide the preparation methods of the pharmaceutical composition of the treatment goat taeniasis.
A kind of pharmaceutical composition for treating goat taeniasis of the present invention, by weight, including following raw material：
16-20 parts of FRUCTUS CARPESII, 12-16 parts of pomegranate root skin, 10-14 parts of discadenoid cherry root, 12-16 parts of rhizome of cyrtomium, 10-14 parts of hawthorn, she
Tie up 0.1-0.3 parts of rhzomorph, 0.1-0.3 parts of albendazole tablet.
A kind of above-mentioned pharmaceutical composition for treating goat taeniasis, by weight, including following raw material：
18 parts of FRUCTUS CARPESII, 14 parts of pomegranate root skin, 12 parts of discadenoid cherry root, 14 parts of rhizome of cyrtomium, 12 parts of hawthorn, 0.2 part of ivermectin, acetysalicylic acid phenobarbital
Up to 0.2 part of azoles piece.
A kind of preparation method of above-mentioned pharmaceutical composition for treating goat taeniasis, includes the following steps：
（1）Each bulk pharmaceutical chemicals are taken by weight；
（2）Chinese medicine is added up into 6-8 times of water of quality, after boiling by intense fire, is cooked by slow fire 25-35min, decocting liquid of fetching water, the dregs of a decoction add again
5-7 times of medicinal material gross weight measures water, after boiling by intense fire, is cooked by slow fire 20-30min, merges decocting liquid twice；
（3）Ivermectin, albendazole tablet are added in Chinese medicine decocting liquid, mixing after dissolving to obtain the final product.
Application method:The drug prepared by the embodiment of the present invention, spice is taken to take, each one is secondary daily morning and evening.
Compared with prior art, the present invention there is apparent advantageous effect, as can be known from the above technical solutions：The present invention selects north
Lappula echinata, pomegranate root skin, discadenoid cherry root, rhizome of cyrtomium, hawthorn, ivermectin, albendazole tablet are raw material, are made by the collaboration of each drug
With play expelling parasite desinsection, strengthening the spleen and stomach, laxative diuresis, qi-regulating and in and other effects, Chinese and Western combine, anthelminthic effect can be improved, and prolong
Slow generation of the parasite to the drug resistance of antimicrobial, can effectively treat goat taeniasis, have rapid-action, good effect, nontoxic pair
Effect, and medication is convenient and efficient.
Specific implementation mode
Embodiment 1
A kind of pharmaceutical composition for treating goat taeniasis, includes the following steps：
（1）Screen bulk pharmaceutical chemicals, weigh FRUCTUS CARPESII 160g, pomegranate root skin 160g, discadenoid cherry root 100g, rhizome of cyrtomium 160g, hawthorn 100g,
Ivermectin 3g, albendazole tablet 1g；
（2）Chinese medicine is added up into 8 times of water of quality, after boiling by intense fire, is cooked by slow fire 25min, decocting liquid of fetching water, dosing material is total again for the dregs of a decoction
7 times of amount water are weighed, after boiling by intense fire, 20min is cooked by slow fire, merges decocting liquid twice；
（3）Ivermectin, albendazole tablet are added in Chinese medicine decocting liquid, mixing after dissolving to obtain the final product.
Embodiment 2
A kind of pharmaceutical composition for treating goat taeniasis, includes the following steps：
（1）Screen bulk pharmaceutical chemicals, weigh FRUCTUS CARPESII 180g, pomegranate root skin 140g, discadenoid cherry root 120g, rhizome of cyrtomium 140g, hawthorn 120g,
Ivermectin 2g, albendazole tablet 2g；
（2）Chinese medicine is added up into 7 times of water of quality, after boiling by intense fire, is cooked by slow fire 30min, decocting liquid of fetching water, dosing material is total again for the dregs of a decoction
6 times of amount water are weighed, after boiling by intense fire, 25min is cooked by slow fire, merges decocting liquid twice；
（3）Ivermectin, albendazole tablet are added in Chinese medicine decocting liquid, mixing after dissolving to obtain the final product.
Embodiment 3
A kind of pharmaceutical composition for treating goat taeniasis, includes the following steps：
（1）Screen bulk pharmaceutical chemicals, weigh FRUCTUS CARPESII 200g, pomegranate root skin 120g, discadenoid cherry root 140g, rhizome of cyrtomium 120g, hawthorn 140g,
Ivermectin 1g, albendazole tablet 3g；
（2）Chinese medicine is added up into 6 times of water of quality, after boiling by intense fire, is cooked by slow fire 35min, decocting liquid of fetching water, dosing material is total again for the dregs of a decoction
5 times of amount water are weighed, after boiling by intense fire, 30min is cooked by slow fire, merges decocting liquid twice；
（3）Ivermectin, albendazole tablet are added in Chinese medicine decocting liquid, mixing after dissolving to obtain the final product.
The above described is only a preferred embodiment of the present invention, being not intended to limit the present invention in any form, Ren Hewei
Be detached from technical solution of the present invention content, according to the technical essence of the invention to made by above example it is any it is simple modification, etc.
With variation and modification, in the range of still falling within technical solution of the present invention.
Claims (3)
1. a kind of pharmaceutical composition for treating goat taeniasis, by weight, including following raw material：
16-20 parts of FRUCTUS CARPESII, 12-16 parts of pomegranate root skin, 10-14 parts of discadenoid cherry root, 12-16 parts of rhizome of cyrtomium, 10-14 parts of hawthorn, she
Tie up 0.1-0.3 parts of rhzomorph, 0.1-0.3 parts of albendazole tablet.
2. a kind of pharmaceutical composition for treating goat taeniasis as described in claim 1, by weight, including following original
Material：
18 parts of FRUCTUS CARPESII, 14 parts of pomegranate root skin, 12 parts of discadenoid cherry root, 14 parts of rhizome of cyrtomium, 12 parts of hawthorn, 0.2 part of ivermectin, acetysalicylic acid phenobarbital
Up to 0.2 part of azoles piece.
3. a kind of pharmaceutical composition for treating goat taeniasis as described in claim 1, preparation method, including following step
Suddenly：
（1）Each bulk pharmaceutical chemicals are taken by weight；
（2）Chinese medicine is added up into 6-8 times of water of quality, after boiling by intense fire, is cooked by slow fire 25-35min, decocting liquid of fetching water, the dregs of a decoction add again
5-7 times of medicinal material gross weight measures water, after boiling by intense fire, is cooked by slow fire 20-30min, merges decocting liquid twice；
（3）Ivermectin, albendazole tablet are added in Chinese medicine decocting liquid, mixing after dissolving to obtain the final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810713321.4A CN108452046A (en) | 2018-06-29 | 2018-06-29 | A kind of pharmaceutical composition and preparation method thereof for treating goat taeniasis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810713321.4A CN108452046A (en) | 2018-06-29 | 2018-06-29 | A kind of pharmaceutical composition and preparation method thereof for treating goat taeniasis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108452046A true CN108452046A (en) | 2018-08-28 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810713321.4A Pending CN108452046A (en) | 2018-06-29 | 2018-06-29 | A kind of pharmaceutical composition and preparation method thereof for treating goat taeniasis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110151910A (en) * | 2019-05-28 | 2019-08-23 | 石家庄九鼎动物药业有限公司 | A kind of antiparasite drugs for animals albendazole ivermectin piece and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101116703A (en) * | 2006-12-25 | 2008-02-06 | 江国潮 | Medicinal food for treating tapeworm disease |
| CN103340313A (en) * | 2013-07-12 | 2013-10-09 | 镇江万山红遍农业园 | Traditional Chinese medicine additive for preventing and treating goat parasite, and application method thereof |
-
2018
- 2018-06-29 CN CN201810713321.4A patent/CN108452046A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101116703A (en) * | 2006-12-25 | 2008-02-06 | 江国潮 | Medicinal food for treating tapeworm disease |
| CN103340313A (en) * | 2013-07-12 | 2013-10-09 | 镇江万山红遍农业园 | Traditional Chinese medicine additive for preventing and treating goat parasite, and application method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 刘俊伟，等: "中药驱虫净散对绵羊消化道寄生虫的驱除试验", 《黑龙江畜牧兽医》 * |
| 唐仕亮: "黑山羊常见疫病与防控", 《兽医导刊》 * |
| 王建国: "验方驱绦虫", 《四川中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110151910A (en) * | 2019-05-28 | 2019-08-23 | 石家庄九鼎动物药业有限公司 | A kind of antiparasite drugs for animals albendazole ivermectin piece and preparation method thereof |
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180828 |
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| WD01 | Invention patent application deemed withdrawn after publication |