CN105194034A - Traditional Chinese medicine composition for preventing and treating bacterial enteritis of aquatic animals - Google Patents
Traditional Chinese medicine composition for preventing and treating bacterial enteritis of aquatic animals Download PDFInfo
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- CN105194034A CN105194034A CN201410306833.0A CN201410306833A CN105194034A CN 105194034 A CN105194034 A CN 105194034A CN 201410306833 A CN201410306833 A CN 201410306833A CN 105194034 A CN105194034 A CN 105194034A
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Abstract
The invention provides a traditional Chinese medicine composition for preventing and treating bacterial enteritis of aquatic animals. The traditional Chinese medicine composition comprises the following ingredients in parts by weight: 59-61 parts of portulaca oleracea, 19-21 parts of Chinese pulsatilla root and 19-21 parts of amur corktree bark and is prepared through the decocting method. According to the traditional Chinese medicine composition, the traditional Chinese medicines are combined reasonably and cooperate with one another, so that the traditional Chinese medicine composition has the efficacy of clearing heat, expelling dampness, astringing to arrest diarrhea, and nourishing the intestines and stomach since all traditional Chinese medicines cooperate with one another; an effective treatment medicine for preventing and treating bacterial enteritis of the aquatic animals is provided for the aquaculture industry and the traditional Chinese medicine composition has the characteristics as follows: the raw materials are easily obtained, the formula is simple, the traditional Chinese medicine composition takes effects quickly, the curative effect is exact, and no medicine residue, low possibility of drug resistance and no any toxic or side effect are realized.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, especially a kind of Chinese medicine composition preventing and treating bacterial enteritis of aquatic livestock.
Background technology
Fish bacterial enteritis disease is modal a kind of fish diseases, and cause of disease is visible peristalsis visible intestinal peristalsis point-like gas vacuole bacterium, is the aquatic animals such as conditioned pathogen, main harm Ctenopharyngodon idellus, Mylopharyngodon piceus, silver carp, flathead.Ctenopharyngodon idellus, Mylopharyngodon piceus all may be infected from fingerling to adult fish, and this sick mortality rate is high, and general death rate is about 50%, and the fishpond mortality rate of falling ill serious can up to more than 90%.Namely general fish bacterial enteritis disease comes into vogue more than 18 DEG C of water temperatures, when epidemic peak is 25-30 DEG C of water temperature, two obvious epidemic season are had in 1 year, the 5-6 month is 1-2 Ctenopharyngodon idellus in age, Mylopharyngodon piceus mainly, the 8-9 month is Ctenopharyngodon idellus morbidity then mainly, all there is generation in area of respectively breeding fish, the whole nation, is that China's feeding fish apoplexy due to endogenous wind endangers one of serious disease.The sick normal and bacterial gill rot disease of fish bacterial enteritis, erythroderma are concurrent, therefore be also called " old three is sick ", its cardinal symptom is that disease fish loss of appetite is not even ingested completely, body colour is turned black, moves about slowly, disease cuts intestinal tube visible intestinal wall contrafluxion inflammation in early days open, food or back segment is not had to have a small amount of food in intestinal, end-stage disease intestinal is aubergine, intestinal wall poor flexibility, mucus is many without food for enteral, the red and swollen evagination of anus, serious macrura reevesii body intraperitoneal has flaxen ascites, has been carried in sick fish head portion, has namely had yellow mucus to flow out from anus.Present stage for bacterial enteritis disease treatment except employing sulfa antibiotics as Sulfaguanidine or sulfanilamide addicted to steep wait treat except, also some Chinese medicine preparation are had, as application number 201010275186.3, disclose a kind of Chinese medicine composition for the treatment of dysentery, it is made up of the raw material of following weight proportioning: fluxweed 13-17, Radix Pulsatillae 13-17, Herba Pteridis Multifidae 28-32, Rhizoma Coptidis 10-14, white red sorrel 13-17, Herb Polygoni Chinensis 28-32, Herba Portulacae 18-22, Cortex Phellodendri 10-14, Herba Acalyphae 10-14, dysentery grass 13-17, Cortex Fraxini 10-14, little grass 18-22, treatment dysentery is effective, and it is cheap, application number 201010606614.6 discloses a kind of Radix Pulsatillae granule for fowl bacterial disease and preparation method thereof, application and premix material, belong to veterinary drug and premix material field, the ingredient of the Radix Pulsatillae granule of this invention is by the Radix Pulsatillae, Rhizoma Coptidis, Cortex Phellodendri, Herba Portulacae, Herba Lysimachiae, Herba Cirsii, Cortex Fraxini, Cortex Ailanthi forms, wherein Radix Pulsatillae 20-60 part, Rhizoma Coptidis 20-40 part, Cortex Phellodendri 20-60 part, Herba Portulacae 20-60 part, Herba Lysimachiae 20-60 part, Herba Cirsii 20-60 part, Cortex Fraxini 20-40 part, Cortex Ailanthi 20-40 part, this invention granule is applicable to the control of fowl bacterial disease.But be not difficult to find out, western medicine produces while drug resistance except easily making the shoal of fish, food safety is also threatened, and the Chinese medicine preparation prescription Chinese medicine component of present stage is various, interact while producing therapeutic effect, toxic and side effects is also bad assessment, therefore, carry out Analysis and Screening to existing Chinese medicinal components, prepare prescription few and reasonable, pharmacologic action is remarkable, the Chinese medicine preparation of few side effects, has very important production practices meaning.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine composition preventing and treating bacterial enteritis of aquatic livestock.
For solving the problems of the technologies described above, the present invention proposes following technical scheme:
Prevent and treat a Chinese medicine composition for bacterial enteritis of aquatic livestock, comprise Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri, by its weight parts Herba Portulacae 59-61 part, Radix Pulsatillae 19-21 part, Cortex Phellodendri 19-21 part.
Preferably, above-mentioned Chinese medicine composition is by its weight parts preferred Herba Portulacae 59.5-60 part, Radix Pulsatillae 20-20.5 part, Cortex Phellodendri 19.5-20 part.
Preferably, above-mentioned Chinese medicine composition is by the preferred Herba Portulacae of its weight parts 60 parts, the Radix Pulsatillae 20.5 parts, Cortex Phellodendri 19.5 parts.
Preferably, the Chinese medicine composition of above-mentioned control bacterial enteritis of aquatic livestock, is obtained by following method:
(1) respectively Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri are carried out micronizing, cross 100-300 mesh sieve;
(2) take Herba Portulacae 59-61 part by weight, Radix Pulsatillae 19-21 part, Cortex Phellodendri 19-21 part is raw material;
(3) water adding medical material gross weight 10-15 times amount after Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri mixing is carried out water extraction, Extracting temperature is 80 DEG C, and extraction time is 12 hours, and room temperature, after static 24 hours, gets supernatant for subsequent use;
(4) be 1.20-1.25 by supernatant concentration in step (3) to relative density, obtain final product.
Preferably, in above-mentioned Chinese medicine composition preparation method, step (4) Chinese medicine finally concentrated relative density is 1.23.
The invention has the beneficial effects as follows:
Above-mentioned control Aquatic product animal bacteria enteritis disease substance is point-like Aerononas punctata, is conditioned pathogen, and when fish body is healthy, this bacterium is in weak tendency, can not be diseases induced; When water body worsen, dissolved oxygen reduce, throw something and feed the cause influences such as feed spoilage time, fish body intestinal microbial population microecological environment can be caused to change, and pathogen becomes pathogenic bacterium, causes extensive bacterial enteritis, thus should in order to clearing heat and expelling damp, astringing to arrest diarrhea, be good for the intestines and stomach be the rule for the treatment of.
In side of the present invention, Herba Portulacae, as the medical material of medicine-food two-purpose, medically has the effect such as heat-clearing and toxic substances removing, QI invigorating tonify deficiency, and its extract has inhibitory action highly to escherichia coli, Bacillus proteus, dysentery bacterium, typhoid fever, Salmonella paratyphi.Radix Pulsatillae bitter in the mouth, cold in nature, return stomach, large intestine channel, there is heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, effect of removing dampness and killing parasites.Cortex Phellodendri property is bitter, cold, return kidney, stomach, large intestine channel, there is heat-clearing and toxic substances removing, the effects such as heat clearing and damp drying, the mutual Synergistic of this prescription, there is effect of clearing heat and expelling damp, astringing to arrest diarrhea, strong the intestines and stomach, for culture fishery provides a kind of effective medicine preventing and treating bacterial enteritis of aquatic livestock, have instant effect, curative effect really, no drug residue, not easily produce drug resistance, feature without any side effects.
This prescription drug is easy to get, not only easy but also save time economical, evident in efficacy, is worthy to be popularized.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme of the present invention is further described.
Embodiment 1
Prevent and treat a Chinese medicine composition for bacterial enteritis of aquatic livestock, be made up of Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri, wherein Herba Portulacae 60g, Radix Pulsatillae 20.5g, Cortex Phellodendri 19.5g.
The preparation method of the Chinese medicine composition of above-mentioned control bacterial enteritis of aquatic livestock, concrete preparation process is as follows:
(1) respectively Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri are carried out micronizing, cross 200 mesh sieves;
(2) take Herba Portulacae 60g, Radix Pulsatillae 20.5g, Cortex Phellodendri 19.5g is raw material;
(3) water adding medical material gross weight 13 times amount after Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri mixing is carried out water extraction, Extracting temperature is 80 DEG C, and extraction time is 12 hours, and room temperature, after static 24 hours, gets supernatant for subsequent use;
(4) be 1.23 by supernatant concentration in step (3) to relative density, obtain final product.
Embodiment 2
Prevent and treat a Chinese medicine composition for bacterial enteritis of aquatic livestock, be made up of Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri, wherein Herba Portulacae 61g, Radix Pulsatillae 19g, Cortex Phellodendri 19g.
The preparation method of the Chinese medicine composition of above-mentioned control bacterial enteritis of aquatic livestock, concrete preparation process is as follows:
(1) respectively Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri are carried out micronizing, cross 300 mesh sieves;
(2) take Herba Portulacae 61g, Radix Pulsatillae 19g, Cortex Phellodendri 19g is raw material;
(3) water adding medical material gross weight 15 times amount after Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri mixing is carried out water extraction, Extracting temperature is 80 DEG C, and extraction time is 12 hours, and room temperature, after static 24 hours, gets supernatant for subsequent use;
(4) be 1.20 by supernatant concentration in step (3) to relative density, obtain final product.
Embodiment 3
Prevent and treat a Chinese medicine composition for bacterial enteritis of aquatic livestock, be made up of Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri, wherein Herba Portulacae 59g, Radix Pulsatillae 21g, Cortex Phellodendri 21g.
The preparation method of the Chinese medicine composition of above-mentioned control bacterial enteritis of aquatic livestock, concrete preparation process is as follows:
(1) respectively Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri are carried out micronizing, cross 100 mesh sieves;
(2) take Herba Portulacae 59g, Radix Pulsatillae 21g, Cortex Phellodendri 21g is raw material;
(3) water adding medical material gross weight 10 times amount after Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri mixing is carried out water extraction, Extracting temperature is 80 DEG C, and extraction time is 12 hours, and room temperature, after static 24 hours, gets supernatant for subsequent use;
(4) be 1.25 by supernatant concentration in step (3) to relative density, obtain final product.
Embodiment 4
Prevent and treat a Chinese medicine composition for bacterial enteritis of aquatic livestock, be made up of Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri, wherein Herba Portulacae 59.5g, Radix Pulsatillae 20.5g, Cortex Phellodendri 20g.
The preparation method of the Chinese medicine composition of above-mentioned control bacterial enteritis of aquatic livestock, concrete preparation process is as follows:
(1) respectively Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri are carried out micronizing, cross 140 mesh sieves;
(2) take Herba Portulacae 59.5g, Radix Pulsatillae 20.5g, Cortex Phellodendri 20g is raw material;
(3) water adding medical material gross weight 14 times amount after Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri mixing is carried out water extraction, Extracting temperature is 80 DEG C, and extraction time is 12 hours, and room temperature, after static 24 hours, gets supernatant for subsequent use;
(4) be 1.22 by supernatant concentration in step (3) to relative density, obtain final product.
Embodiment 5
Prevent and treat a Chinese medicine composition for bacterial enteritis of aquatic livestock, be made up of Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri, wherein Herba Portulacae 60g, Radix Pulsatillae 20g, Cortex Phellodendri 19.5g.
The preparation method of the Chinese medicine composition of above-mentioned control bacterial enteritis of aquatic livestock, concrete preparation process is as follows:
(1) respectively Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri are carried out micronizing, cross 260 mesh sieves;
(2) take Herba Portulacae 60g, Radix Pulsatillae 20g, Cortex Phellodendri 19.5g is raw material;
(3) water adding medical material gross weight 12 times amount after Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri mixing is carried out water extraction, Extracting temperature is 80 DEG C, and extraction time is 12 hours, and room temperature, after static 24 hours, gets supernatant for subsequent use;
(4) be 1.24 by supernatant concentration in step (3) to relative density, obtain final product.
The described Chinese crude drug of one of embodiment 1-5 is commercially available prod, and each amounts of components increased according to same ratio or reduce, the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
The described Chinese crude drug of one of embodiment 1-5 all meets " Chinese veterinary pharmacopoeia " version two ministerial standard in 2010.
The composition principle of Chinese medicine composition of the present invention is: in side, Herba Portulacae enters the heart, liver, spleen, large intestine channel, and heat-clearing and toxic substances removing, diuretic dry, fall apart blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, hemostasis removing heat from blood; The Radix Pulsatillae returns stomach, large intestine channel, has effect of heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, removing dampness and killing parasites; Cortex Phellodendri returns kidney, bladder, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat.All medicines share, mutual Synergistic, remarkably productive to control bacterial enteritis of aquatic livestock, especially adopt proportioning described in embodiment 1, and effect of anti-inflammatory analgetic, eliminating fire and detoxication is very remarkable, is particularly applicable to the control of bacterial enteritis of aquatic livestock.
Clinical trial example:
10 mu, Tianjin Jinghai County crawl, the depth of water 1 meter, in August, 2012, there is disease fish in pond culture Ctenopharyngodon idellus, and sick fish belly portion expands, and presents erythema, and anus is given prominence to, and fish body is the symptom such as dull, serious appearance fish kills phenomenon.Analysis reason of catching an illness is: along with temperature rises gradually, and sashimi (raw fish) is long very fast, and various pathogenic bacterium increase sharply; In addition to throw something and feed for a long time defective feedstuff or high protein feed, cause fish nutrition metabolism bad, body constitution declines, and body fat accumulates; Add antibiotic in feed a part, result in hepatic lesions; Condition of water quality worsens for a long time, and in pond, hydrogen sulfide, ammoniacal nitrogen severe overweight, make Fish chronic poisoning.
Then Chinese medicine composition described in embodiment 1 is used to treat, this Chinese medicine composition of 50ml (5ml/ mu water body) is evenly poured in crawl, use after 3 days, sampling inspection fish diseased region, sampling results shows, Fish diseased region takes an evident turn for the better, improvement rate reaches 98%, this Chinese medicine composition of rear employing proceeds the prevention of bacterial enteritis, and each moon uses once, and sickness rate comparatively reduces 15% the same period in former years.
Above-mentioned reference embodiment is the detailed description of the Chinese medicine composition to this control bacterial enteritis of aquatic livestock; illustrative instead of determinate; several embodiments can be listed according to institute's limited range; therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (3)
1. prevent and treat a Chinese medicine composition for bacterial enteritis of aquatic livestock, it is characterized in that: be made up of Herba Portulacae, the Radix Pulsatillae and Cortex Phellodendri, by its weight parts Herba Portulacae 59-61 part, Radix Pulsatillae 19-21 part, Cortex Phellodendri 19-21 part.
2. the Chinese medicine composition of control bacterial enteritis of aquatic livestock according to claim 1, is characterized in that: by its weight parts Herba Portulacae 59.5-60 part, Radix Pulsatillae 20-20.5 part, Cortex Phellodendri 19.5-20 part.
3. the Chinese medicine composition of control bacterial enteritis of aquatic livestock according to claim 1 and 2, is characterized in that: by its weight parts Herba Portulacae 60 parts, the Radix Pulsatillae 20.5 parts, Cortex Phellodendri 19.5 parts.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105660488A (en) * | 2016-03-22 | 2016-06-15 | 五河县金塘水产养殖有限公司金贸园分公司 | Aquaculture method capable of controlling enteritis of crucian carps |
| CN105687508A (en) * | 2016-03-22 | 2016-06-22 | 五河县金塘水产养殖有限公司金贸园分公司 | Medicinal composition for preventing and treating crucian enteritis |
| CN110314186A (en) * | 2019-07-09 | 2019-10-11 | 爱迪森(北京)生物科技有限公司 | A kind of Chinese medicine composition and preparation method thereof for preventing and treating aquatic livestock enteritis |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105660488A (en) * | 2016-03-22 | 2016-06-15 | 五河县金塘水产养殖有限公司金贸园分公司 | Aquaculture method capable of controlling enteritis of crucian carps |
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| CN110314186A (en) * | 2019-07-09 | 2019-10-11 | 爱迪森(北京)生物科技有限公司 | A kind of Chinese medicine composition and preparation method thereof for preventing and treating aquatic livestock enteritis |
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