CN108451862A - A kind of facial cleanser and preparation method thereof containing sealwort with moisturizing repair function - Google Patents
A kind of facial cleanser and preparation method thereof containing sealwort with moisturizing repair function Download PDFInfo
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- CN108451862A CN108451862A CN201810669087.XA CN201810669087A CN108451862A CN 108451862 A CN108451862 A CN 108451862A CN 201810669087 A CN201810669087 A CN 201810669087A CN 108451862 A CN108451862 A CN 108451862A
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- repair function
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Abstract
The invention discloses a kind of facial cleansers containing sealwort with moisturizing repair function, are mainly prepared by the raw material of following weight：15 25 parts of sealwort extracting solution；12 15 parts of butanediol；45 parts of pentanediol；45 parts of polymer hyaluronic acid；25 35 parts of amino acid foaming agent；35 parts of trehalose；45 parts of urea；34 parts of thickener；22 40 parts of water.The dairy products of washing one's face, formulation efficacy is clearly stablized, mainly by Chinese medicine Rhizoma Polygonati extract as function effective component, pass through the mutual compatibility effect between above-mentioned each material composition, have long-acting moisturizing, clean anti-inflammatory and skin repair effect, and effect is mildly safe, it is used suitable for various skin quality, effectively overcome natural skin care product effect unstable, or pure chemistry ingredient prepare wash shield product irritation it is big, the disadvantages such as safety coefficient is low, expand sealwort medicinal material external application drug effect and its application value in washing product field.The invention also discloses a kind of preparation methods of the facial cleanser with moisturizing repair function containing sealwort.
Description
Technical field
It is the invention belongs to daily use chemicals cleaning supplies technical field, more particularly to a kind of that there is washing for moisturizing repair function containing sealwort
Face milk.
Background technology
With the improvement of living standard, requirement of the people to daily cleaning skin care item is also higher and higher.Facial cleanser is as one
The facial cleaning articles for use of kind should also be with extra-nutrition, protection skin and other effects in addition to having basic facial cleaning function.But
Current market sales of facial cleanser, most of help effects for not having skin whitening and anti-inflammatory reparation；Has above-mentioned help
The facial cleanser of effect is then made containing a large amount of chemical substances mostly, and to skin irritation, many people will appear skin mistake after
Quick equal adverse reactions, huge puzzlement is brought to user.
China has abundant Chinese medicine medicine resource as traditional Chinese medicine big country.Chinese medicine is dissolved into washing one's face dairy products, from
And it mild, safe Traditional Chinese medicine facial cleanser is prepared has become prepared by current facial cleanser one and be very popular trend.To such as have U.S.
The Chinese medicinal materials such as Perilla frutescens, the root of Dahurain angelica of baiyao effect, the facial cleanser etc. with white-skinned face function prepared as raw materials for production.
Sealwort, as a kind of Chinese medicinal herbs of integration of drinking and medicinal herbs, specifically Liliaceae HUANGJING ZANYU CAPSULE P. kingianum
Polygonatum kingia-num Col1.etHemsl., sealwort PolygonatumsibiricumRed. or David's-harp
The dry rhizome of Polygonatum cyrtonema Hua.Sweet in flavor and neutral in nature is the product of the help of taste boosting qi and nourishing yin.
At this stage with to sealwort drug efficacy study, more deep understanding is achieved both at home and abroad, obtain more and more
Concern.Sealwort has improvement result to weak, physically weak, shortness of breath, cardio palmus shape.It can also be used to treat coronary heart disease, diabetes, high blood
The various diseases such as fat disease, low blood pressure, chronic bronchitis, drug poisoning deafness, leukopenia, ishemic stroke.With
To sealwort pharmacology, pharmaceutical chemistry and clinical research gradually deeply, the active ingredient of HUANGJING ZANYU CAPSULE and active site
Research is also paid attention to by new drug development.Modern pharmacological studies have shown that sealwort and its polysaccharide have blood pressure lowering, antitumor, reducing blood lipid,
The wide applications such as immune, improvement memory are adjusted, reference is provided for sealwort clinical application and utilization.
But it is fewer and fewer to the research of sealwort and its Siberian solomonseal rhizome polysaccharide external application at present, so far, there are no using sealwort as
Only taste Chinese medicine material has effects that the technology report of facial cleanser is repaired in moisturizing for preparing.The present invention to sealwort external application drug effect into
Row is explored, and the potential value of sealwort and its polysaccharide external application is deeply excavated and grasp, and promotes the development of Chinese medicine sealwort industrial chain, fully
Play the maintenance drug action of sealwort.
Invention content
That the purpose of the present invention is to provide a kind of using effects is good, safety is mild has moisturizing repair function containing sealwort
Facial cleanser, the preparation method for providing the facial cleanser is the another object of the invention.
In order to achieve the above-mentioned object of the invention, the present invention provides following technical schemes：
A kind of facial cleanser containing sealwort with moisturizing repair function, which is characterized in that by sealwort extracting solution and facial cleanser base
Matter, according to weight 1：15-25 is formulated；Wherein, the facial cleanser matrix, includes the raw material of following weight
Composition：12-15 parts of butanediol；4-5 parts of pentanediol；4-5 parts of polymer hyaluronic acid；25-35 parts of foaming agent；3-5 parts of trehalose；
4-5 parts of urea；3-4 parts of thickener；30-40 parts of water.
According to above-mentioned technical proposal, the present invention provides a kind of sealwort extraction by sealwort Chinese medicinal material after refluxing extraction
Liquid, with above-mentioned facial cleanser matrix components substance, the Chinese herbal medicine facial cleanser prepared by the weight relationship.
Through inventor the study found that the chemical composition in sealwort has polysaccharide, steroid saponin, flavonoids, amino acid, lignanoid
Etc. the effective component for oral administration for playing effective health-care effect, external application has antibacterial, antibacterial and provide nutrition for skin repair, plays
Promote the function of skin repair and anti-aging.Polysaccharide is as the higher ingredient of content in sealwort, externally used antimicrobial, antibacterial and promotion
Skin new life function is the most notable.By fresh sealwort extracting solution for carrying out specific Effect of Alcohol Extracting Procedureto Total of the present invention and obtaining of sealwort
The content of drug effect components such as middle Siberian solomonseal rhizome polysaccharide significantly improve.
Also, when preparing the sealwort extracting solution and above-mentioned matrix components according to above-mentioned special ratios, in sealwort extracting solution
Polysaccharide and the effective components substance such as amino acid, can be with alcohols, amino acids and the hyalomitome acids in the matrix components
Chemical matrix ingredient shows good significantly co-melting synergy, so that gained sealwort is washed one's face dairy products, appearance color color
Height, texture exquisiteness is smooth, smell faint scent, and is also equipped with long-acting moisturizing and significantly cleans anti-inflammatory and skin repair effect.In addition,
The dairy products of washing one's face, formulation efficacy are clearly stablized, and mainly by Chinese medicine Rhizoma Polygonati extract as function effective component, effect is mildly pacified
Entirely, it is suitable for various skin quality to use, effectively overcomes natural skin care product effect unstable or prepared by pure chemistry ingredient washes shield production
The disadvantages such as product irritation is big, and safety coefficient is low.
Preferably, a kind of containing the facial cleanser containing sealwort with moisturizing repair function, by sealwort extracting solution and facial cleanser matrix,
According to weight 1：15 are formulated；Wherein, the facial cleanser matrix includes the raw material composition of following weight：
15 parts of butanediol；5 parts of pentanediol；5 parts of polymer hyaluronic acid；35 parts of foaming agent；5 parts of trehalose；5 parts of urea；Thickener 3
Part；30 parts of water.
Through inventor experimental studies have found that, by sealwort wash one's face each material composition of dairy products weight it is further excellent
When selecting above range, gained wash one's face dairy products appearance luster it is brighter, the breast matter texture that color shades are more attractive, product is shown
It is fine and smooth smooth.
Further, the sealwort extracting solution is made especially by following method：
S1：Clean fresh sealwort is taken, is crushed after slice, 20-80 mesh sieve is crossed, obtains sealwort powder；
S2：Above-mentioned sealwort powder is taken, according to solid-liquid ratio 1：10-20 adds water to mix；
S3：By mixed sealwort powder liquid, refluxing extraction 2 times, each reflux extracting time is 1-2h to get the sealwort
Extracting solution.
The present invention specially selects the effective substances content such as polysaccharide and steroid saponin, flavonoids, amino acid, lignanoid highest
Fresh sealwort directly carries out refluxing extraction with clear water after crushed as extraction raw material, by sealwort grinding particle size, sealwort
Powder adds the preferred restriction of water mixture liquor ratio and reflux extracting time, remarkably promote Siberian solomonseal rhizome polysaccharide etc. with moisturizing anti-inflammatory, antibacterial and
The release and extraction of the active principle ingredient of skin repair function, improve sealwort extracting solution in polyoses content characterization drug effect at
Divide substance extraction and application rate.
Preferably, sealwort powder crosses 50-70 mesh sieve in step S1；The mixed liquor of sealwort powder and water ratio is in the step S2
1:15；Each reflux extracting time is 1.5h in the step S3.
Show through inventor's experimental study：Respectively preferably by above-mentioned sealwort Effect of Alcohol Extracting Procedureto Total state modulator in the range
When interior, Siberian solomonseal rhizome polysaccharide recovery rate reaches as high as 10% or more, further increases the extraction and application efficiency of sealwort effective component.
Further, the foaming agent is amino acid foaming agent, including ms-11 powder of amino acids foaming agent and No. 2 amino acid
One or more of foaming agent.It is highly preferred that the weight of the ms-11 powder of amino acids foaming agent and No. 2 amino acid foaming agents
It is 2-5 to measure part proportioning:1-2.
Another object of the present invention is to provide a kind of preparation side of the above-mentioned facial cleanser with moisturizing repair function containing sealwort
Method makes products'texture exquisiteness stablize to ensure the co-melting compatibility between each material composition, it is more preferable play the drug effects such as Siberian solomonseal rhizome polysaccharide at
Divide and long-acting moisturizing, the anti-inflammatory and skin repair efficacy exertion of cleaning after the compatibility of each matrix components.
A kind of preparation method of the facial cleanser with moisturizing repair function containing sealwort, includes the following steps：
A, raw material is classified：Foaming agent, butanediol and pentanediol is weighed to be placed in A containers, then weigh polymer hyaluronic acid,
Urea, trehalose, thickener and water are placed in B containers；
B, the pre-heat treatment：By the raw material in above-mentioned A containers and B containers, it is preheated to 80-90 DEG C respectively；
C, mixing and emulsifying：By the raw material in the raw material and B containers in A containers after preheating, mix while stirring, and be maintained at
80-90 DEG C of emulsified 10-20min；
D, sealwort extracting solution is added：Mixing speed is reduced, waits for that temperature is down to 60 DEG C, sealwort water, which is added, according to component proportion carries
Liquid, at a slow speed uniform stirring stop heating to after 48 DEG C, after room temperature, bottling to get it is described have containing sealwort protect
The dairy products of washing one's face of wet repair function.
According to above-mentioned technical proposal, to make to merge uniformly between material composition, the present invention specially uses raw material to classify
Hybrid mode by advance by amino acid foaming agent, butanediol and the pentanediol in oil phase in facial cleanser matrix components, and is in
Polymer hyaluronic acid, urea, trehalose, thickener and the water of water phase, are separately preheated to 80-90 DEG C, make the matrix in two-phase
Material composition achievees the effect that premixing by similar substance characteristics and preheating diffusion principle.It is maintained at 80-90 DEG C of condition again
Under, so that two-phase matrix components is sufficiently mixed emulsification, improves the fine and smooth smoothness of final products obtained therefrom.Then, it is maintained at 60 DEG C
The mixing of sealwort extracting solution is added, makes the effective component in sealwort extracting solution and mutually doping mixes between matrix components, further
While promoting matrix texture sophistication, make urea in the effective components such as Siberian solomonseal rhizome polysaccharide and matrix, polymer hyaluronic acid at
It after the chemical combination ingredient that grades cooperates with compatibility, obtains that moisturizing is more efficient, and is provided simultaneously with anti-inflammatory and skin repair function facial cleanser production
Product.
Compared with prior art, beneficial effects of the present invention：
1, present invention discover that sealwort extracting solution with by butanediol, pentanediol, polymer hyaluronic acid, trehalose, thickener
Good compatibility effect can be played between the particular substrate formula of water composition, and the two is closed according to formula rate of the present invention
Dairy products of washing one's face prepared by system has long-acting moisturizing, cleans the effect of anti-inflammatory and skin repair, further expands outside sealwort medicinal material
Application with drug effect and its in washing product field.
2, the present invention successfully overcomes existing sealwort to extract by preferably limiting technological parameter in sealwort reflux extraction method
The abundant extraction and application rate of sealwort raw medicinal material is greatly improved in the not high defect of recovery rate in technique, reduces the production of sealwort facial cleanser
The manufacturing cost of product, industrialization practical value are high.
3, the dairy products of washing one's face containing sealwort with moisturizing repair function of the present invention, formulation efficacy are clearly stablized, and
Mild safety is suitable for various skin quality and uses, and effectively overcomes natural skin care product effect unstable or is prepared by pure chemistry ingredient
Wash the disadvantages such as shield product irritation is big, and safety coefficient is low.
Description of the drawings：
Fig. 1 shows the influence that solid-liquid ratio extracts Siberian solomonseal rhizome polysaccharide.
Influence Fig. 2 shows sealwort grinding particle size to Siberian solomonseal rhizome polysaccharide recovery rate.
Fig. 3 shows influence of the extraction time to Siberian solomonseal rhizome polysaccharide recovery rate.
Fig. 4 be in contrast test example 1 according to experiment numbers be 1 matrix formulations prepare sealwort wash one's face dairy products material object photograph
Piece.
Fig. 5 be in contrast test example 1 according to experiment numbers be 2 matrix formulations prepare sealwort wash one's face dairy products material object photograph
Piece.
Fig. 6 be in contrast test example 1 according to experiment numbers be 3 matrix formulations prepare sealwort wash one's face dairy products material object photograph
Piece.
Fig. 7 be in contrast test example 1 according to experiment numbers be 4 matrix formulations prepare sealwort wash one's face dairy products material object photograph
Piece.
Fig. 8 be in contrast test example 1 according to experiment numbers be 5 matrix formulations prepare sealwort wash one's face dairy products material object photograph
Piece.
Specific implementation mode
With reference to test example and specific implementation mode, the present invention is described in further detail.But this should not be understood
It is only limitted to embodiment below for the range of the above-mentioned theme of the present invention, it is all that this is belonged to based on the technology that the content of present invention is realized
The range of invention.
Embodiment 1
A kind of facial cleanser containing sealwort with moisturizing repair function, by sealwort extracting solution and facial cleanser matrix, according to weight
Part proportioning 1：15 are formulated；Wherein, the facial cleanser matrix includes the raw material composition of following weight：Butanediol 15
Part；5 parts of pentanediol；5 parts of polymer hyaluronic acid；25 parts of ms-11 powder of amino acids foaming agent；No. 2 10 parts of amino acid foaming agent；
5 parts of trehalose；5 parts of urea；No. 12 parts of face cleaning cream thickener；No. 21 part of face cleaning cream thickener；30 parts of water.Preparation method is specific
It is as follows：
1, the preparation of sealwort extracting solution：Clean fresh sealwort after crushing after slice, crosses 60 mesh sieve, obtaining granularity is about
0.5cm2Sealwort powder.Again by above-mentioned sealwort powder, according to solid-liquid ratio 1:It after 15 add water mixing, is placed in refluxing extraction device, flows back
Extraction 2 times, each refluxing extraction 1.5h is obtained, reflux extracting liquid, as sealwort extracting solution.
2, matrix material ingredients classification the pre-heat treatment：Weigh the amino acid foaming agent of the weight, butanediol and
Pentanediol is placed in A containers, then weighs polymer hyaluronic acid, urea, trehalose, thickener and the water of the weight
It is placed in B containers；Again by the raw material in above-mentioned A containers and B containers, it is preheated to 85 DEG C respectively；
3, the mixing and emulsifying of matrix components：By the raw material in the raw material and B containers in A containers after preheating, mix while stirring
It closes, and is maintained at 85 DEG C of emulsified 10min；
4, sealwort extracting solution is added：Mixing speed is reduced, waits for that temperature is down to 60 DEG C, sealwort water, which is added, according to component proportion carries
Liquid, at a slow speed uniform stirring stop heating to after 48 DEG C, after room temperature, bottling to get it is described have containing sealwort protect
The dairy products of washing one's face of wet repair function.
Embodiment 2
A kind of facial cleanser containing sealwort with moisturizing repair function, by sealwort extracting solution and facial cleanser matrix, according to weight
Part proportioning 1：20 are formulated；Wherein, the facial cleanser matrix includes the raw material composition of following weight：Butanediol 12
Part；54 parts of pentanediol；5 parts of polymer hyaluronic acid；20 parts of ms-11 powder of amino acids foaming agent；No. 25 parts of amino acid foaming agent；
3 parts of trehalose；4 parts of urea；No. 11 part of face cleaning cream thickener；No. 2 12 parts of face cleaning cream thickener；22 parts of water.Preparation method has
Body is as follows：
1, the preparation of sealwort extracting solution：Clean fresh sealwort smashes it through 70 mesh sieve after slice, and obtaining granularity is about
0.4cm2Sealwort powder.Again by above-mentioned sealwort powder, according to solid-liquid ratio 1:It after 20 add water mixing, is placed in refluxing extraction device, flows back
Extraction 2 times, each refluxing extraction 2h is obtained, reflux extracting liquid, as sealwort extracting solution.
2, matrix material ingredients classification the pre-heat treatment：Weigh the amino acid foaming agent of the weight, butanediol and
Pentanediol is placed in A containers, then weighs polymer hyaluronic acid, urea, trehalose, thickener and the water of the weight
It is placed in B containers；Again by the raw material in above-mentioned A containers and B containers, it is preheated to 80 DEG C respectively；
3, the mixing and emulsifying of matrix components：By the raw material in the raw material and B containers in A containers after preheating, mix while stirring
It closes, and is maintained at 80 DEG C of emulsified 20min；
4, sealwort extracting solution is added：Mixing speed is reduced, waits for that temperature is down to 60 DEG C, sealwort water, which is added, according to component proportion carries
Liquid, at a slow speed uniform stirring stop heating to after 48 DEG C, after room temperature, bottling to get it is described have containing sealwort protect
The dairy products of washing one's face of wet repair function.
Embodiment 3
A kind of facial cleanser containing sealwort with moisturizing repair function, by sealwort extracting solution and facial cleanser matrix, according to weight
Part proportioning 1：25 are formulated；Wherein, the facial cleanser matrix includes the raw material composition of following weight：Butanediol 15
Part；5 parts of pentanediol；5 parts of polymer hyaluronic acid；20 parts of ms-11 powder of amino acids foaming agent；No. 2 10 parts of amino acid foaming agent；
5 parts of trehalose；5 parts of urea；3 parts of thickener；30 parts of water.Preparation method is specific as follows：
1, the preparation of sealwort extracting solution：Clean fresh sealwort after crushing after slice, crosses 50 mesh sieve, obtaining granularity is about
0.6cm2Sealwort powder.Again by above-mentioned sealwort powder, according to solid-liquid ratio 1:It after 10 add water mixing, is placed in refluxing extraction device, flows back
Extraction 2 times, each refluxing extraction 1h is obtained, reflux extracting liquid, as sealwort extracting solution.
2, matrix material ingredients classification the pre-heat treatment：Weigh the amino acid foaming agent of the weight, butanediol and
Pentanediol is placed in A containers, then weighs polymer hyaluronic acid, urea, trehalose, thickener and the water of the weight
It is placed in B containers；Again by the raw material in above-mentioned A containers and B containers, it is preheated to 90 DEG C respectively；
3, the mixing and emulsifying of matrix components：By the raw material in the raw material and B containers in A containers after preheating, mix while stirring
It closes, and is maintained at 90 DEG C of emulsified 10-20min；
4, sealwort extracting solution is added：Mixing speed is reduced, waits for that temperature is down to 60 DEG C, sealwort water, which is added, according to component proportion carries
Liquid, at a slow speed uniform stirring stop heating to after 48 DEG C, after room temperature, bottling to get it is described have containing sealwort protect
The dairy products of washing one's face of wet repair function.
Comparative example 1
A kind of facial cleanser, by sealwort extracting solution and facial cleanser matrix, according to weight 1：10 are formulated；Wherein,
The facial cleanser matrix includes the raw material composition of following weight：12 parts of butanediol；54 parts of pentanediol；Macromolecule is transparent
5 parts of matter acid；20 parts of ms-11 powder of amino acids foaming agent；No. 25 parts of amino acid foaming agent；3 parts of trehalose；4 parts of urea；Face cleaning cream
No. 11 part of thickener；No. 2 12 parts of face cleaning cream thickener；22 parts of water.Preparation method is the same as embodiment 1.
Comparative example 2
A kind of facial cleanser, by sealwort extracting solution and facial cleanser matrix, according to weight 1：30 are formulated；Wherein,
The facial cleanser matrix includes the raw material composition of following weight：12 parts of butanediol；54 parts of pentanediol；Ms-11 amino acid
20 parts of powder foaming agent；No. 25 parts of amino acid foaming agent；3 parts of trehalose；4 parts of urea；No. 11 part of face cleaning cream thickener；Face cleaning cream
No. 2 12 parts of thickener；22 parts of water.Preparation method is the same as embodiment 1.
Comparative example 3
The comparative example relative to embodiment 1 be arranged, with embodiment 1 difference lies in：Omit embodiment 1 in each raw material at
The operation of sealwort extracting solution is added in the pre- hot mixing of classification and substep, is changed to each material composition relationship by weight ratio
After weighing, mixing and emulsifying step is heated together.It is specific as follows：
A kind of facial cleanser, by sealwort extracting solution and facial cleanser matrix, according to weight 1：15 are formulated；Wherein,
The facial cleanser matrix includes the raw material composition of following weight：15 parts of butanediol；5 parts of pentanediol；Macromolecule hyalomitome
5 parts of acid；25 parts of ms-11 powder of amino acids foaming agent；No. 2 10 parts of amino acid foaming agent；5 parts of trehalose；5 parts of urea；Face cleaning cream
No. 12 parts of thickener；No. 21 part of face cleaning cream thickener；30 parts of water.Preparation method is specific as follows：
1, the preparation of sealwort extracting solution：Clean fresh sealwort smashes it through 60 mesh sieve after slice, and obtaining granularity is about
0.5cm2Sealwort powder.Again by above-mentioned sealwort powder, according to solid-liquid ratio 1:It after 15 add water mixing, is placed in refluxing extraction device, flows back
Extraction 2 times, each refluxing extraction 1.5h is obtained, reflux extracting liquid, as sealwort extracting solution.
2, raw material heating mixing：By the weight relationship, above-mentioned all material compositions are weighed, further and appearance are added
In device, 85 DEG C are heated to, is stirred, and is maintained at 85 DEG C of emulsified 10min；
3, it after after naturally cool to room temperature, bottles to get the dairy products of washing one's face containing sealwort with moisturizing repair function.
Contrast test example 1
Influence of the matrix formulations component difference to sealwort facial cleanser products'texture characteristic
This test case is made by the way that 5 groups of different substrates experimental formula group as shown in Table 1 is arranged with reference to described in embodiment 1
Preparation Method, by the sealwort extracting solution compatibility of weight described in each matrix formulations in table 1 and embodiment 1, be prepared as
Fig. 4-products shown in Fig. 8.And the appearance physical characteristic by observing a product, to measure matrix formulations component difference to Huang
Fine purifiation face dairy products texture characteristic influences.
1 five kinds of different substrates prescription experimental conditions tables (parts by weight) of table
It is sequentially modulated to obtain the product as shown in Fig. 4-Fig. 8 according to above-mentioned five kinds of matrix prescriptions, by observing above-mentioned five kinds of bases
The indexs such as the fine and smooth smoothness of matter products'texture, cold-resistant heat-resistant stability, color and luster, smell, find：Match according to No. 3 and No. 4 matrix
The sealwort extracting solution of side and fixed weight part proportioning, the dairy products of washing one's face (6, No. 4 corresponding diagrams 7 of No. 3 corresponding diagrams) of compatible preparation,
Appearance luster evenly, texture it is relatively finer and smoother smooth, and be in faint scent, various aspects characteristic is significantly better than that other 3 kinds.Its
In, particularly preferably according to the dairy products of washing one's face (as shown in Figure 6) obtained by No. 3 matrix formulations, products'texture exquisiteness smoothness highest,
Appearance characteristics are best.
Contrast test example 2
This group of contrast test example is measured in following each test case using phenol-sulfuric acid and colorimetric method obtained by each group extraction process
Siberian solomonseal rhizome polysaccharide content in sealwort extracting solution, to measure in sealwort Effect of Alcohol Extracting Procedureto Total each technological parameter to the shadow of sealwort recovery rate
It rings.Specific experimental method is as follows：
1, the foundation of glucose standard curve
Sealwort slice is weighed, is crushed, sieve takes powder, and 15 times of amount water, refluxing extraction 2 times are added, and each 1.5h takes filtrate,
Concentration.Be added with the absolute ethyl alcohol of concentrate equivalent, so that filtrate alcohol content is reached 50%, therefore the polysaccharide in precipitable filtrate.It is cold
It hides overnight, takes supernatant, 3000r/min to centrifuge 10min, discard precipitation, add after Rotary Evaporators are concentrated under reduced pressure into no alcohol taste
Enter the absolute ethyl alcohol of 3 times of volumes, precipitate Siberian solomonseal rhizome polysaccharide, 40 DEG C of drying preserve.Suitable Siberian solomonseal rhizome polysaccharide is weighed, with distilled water constant volume
To 100mL, make test solution.
Above-mentioned test solution, reference substance solution and blank solution are compared one by one again.Above-mentioned Siberian solomonseal rhizome polysaccharide is taken to supply
Test sample solution, respectively in the glucose solution to scale test tube of 100 μ g/mL of accurate gradient measurement, distilled water is settled to 2.0mL,
The phenol solution of 1.0mL 5% is added, mixing adds the concentrated sulfuric acid of 5.0mL 98%, mixing.Develop the color 20min at room temperature, with
Blank solution measures absorbance (A) at wavelength 490nm.With absorbance A (Y) for ordinate, the concentration μ g/ml (X) of glucose
Recurrence processing is carried out for abscissa, it is Y=7.1405X+0.1959, R to obtain regression equation2=0.9993, the results showed that, grape
Sugar has good linear relationship, glucose detection standard curve to be successfully established within the scope of 5.0~15 μ g/ml.
2, influence of the solid-liquid ratio to Siberian solomonseal rhizome polysaccharide recovery rate
The clean sealwort slice 100g for taking 5 parts of equivalent, is crushed to 0.5cm respectively2Granule size, then respectively according to feed liquid
Than：1：5、1：10、1：15、1：20、1：25, after the drinking water of corresponding times of amount is added, unified refluxing extraction number 2 times returns every time
Under conditions of stream extraction 1.5h, filtrate obtained by refluxing extraction is carried out, after concentration to Solomonseal Rhizome, as each group sealwort extracting solution.
The absorbance for being measured polysaccharide in each group sealwort extracting solution using above-mentioned phenol-sulfuric acid and colorimetric method again, is carried to measure Siberian solomonseal rhizome polysaccharide
Take rate.Laboratory test results are as shown in Figure 1.
According to known to Fig. 1：With the variation of solid-liquid ratio, the recovery rate of Siberian solomonseal rhizome polysaccharide also has different degrees of variation.When
It is preferred that controlling the solid-liquid ratio of sealwort part and water 1:When 10-20 ranges, the Siberian solomonseal rhizome polysaccharide recovery rate in gained sealwort extracting solution,
It is significantly higher than the recovery rate of Siberian solomonseal rhizome polysaccharide in the sealwort extracting solution under other solid-liquid ratios.Particularly preferably, sealwort powder and water are controlled
Mixed liquor ratio is 1:When 15, Siberian solomonseal rhizome polysaccharide recovery rate highest in gained extracting solution.
3, influence of the sealwort grinding particle size to Siberian solomonseal rhizome polysaccharide recovery rate
The clean sealwort slice 100g for taking 5 parts of equivalent, is crushed to 0.2cm respectively2、0.4cm2、0.6cm2、0.8cm2、
1.2cm2Granule size, then unify respectively according to solid-liquid ratio 1:After 15 are added drinking water mixing, refluxing extraction number 2 times, every time
Solomonseal Rhizome is extracted under conditions of refluxing extraction 1.5h.And sealwort obtained by different grain size Solomonseal Rhizome refluxing extraction is carried
Liquid is taken, the absorbance of polysaccharide in each group sealwort extracting solution is measured with above-mentioned phenol-sulfuric acid and colorimetric method, is carried to measure Siberian solomonseal rhizome polysaccharide
Take rate.Laboratory test results are as shown in Figure 2.
Shown in Fig. 2 the experimental results showed that：With the variation of grinding particle size, the recovery rate of Siberian solomonseal rhizome polysaccharide also has different journeys
The variation of degree.When preferably by sealwort pulverizing medicinal materials granularity be 0.4-0.6cm2When, polysaccharide extract rate is significantly high in sealwort extracting solution
Recovery rate under other grinding particle sizes.Particularly preferably by sealwort pulverizing medicinal materials to 0.5cm2When, polysaccharide carries in sealwort extracting solution
Take rate highest.
4, influence of the extraction time to Siberian solomonseal rhizome polysaccharide recovery rate
Respectively select extraction time be 1.0,1.5,2.0h, solid-liquid ratio 1：15, grinding particle size 0.5cm2, extraction time 2
Solomonseal Rhizome is extracted under conditions of secondary.And under the conditions of using phenol-sulfuric acid and colorimetric method to measure different extraction times, sealwort
The absorbance of polysaccharide in sealwort extracting solution obtained by powder refluxing extraction, to measure Siberian solomonseal rhizome polysaccharide recovery rate.Laboratory test results
As shown in Figure 3.
According to shown in Fig. 3 the experimental results showed that：With the variation of extraction time, the recovery rate of Siberian solomonseal rhizome polysaccharide also has difference
The variation of degree.When preferably controlling each reflux extracting time in 1-2h, polyoses content is opposite in gained sealwort extracting solution
It is higher.Particularly preferably, each refluxing extraction 1.5h, polyoses content is significantly improved to 12% or so in gained sealwort extracting solution, right
The extraction and application rate highest of sealwort medicinal material.
Known to all test results of cumulated volume test case：During preparing sealwort extracting solution raw material, to fresh sealwort
When carrying out clear water refluxing extraction, control sealwort pulverizing medicinal materials to 0.4-0.6cm2Sealwort powder, the sealwort powder and clear water are mixed
The solid-liquid ratio of conjunction is 10-20:1,2 refluxing extractions are carried out, under the process conditions of each refluxing extraction 1-2h, to polysaccharide in sealwort
It is opposite etc. the extraction and application rate of useful effective component to significantly improve.Particularly preferably, it controls sealwort pulverizing medicinal materials to 0.5cm2's
Sealwort powder, the solid-liquid ratio that the sealwort powder is mixed with clear water are 15:1,2 refluxing extractions are carried out, each refluxing extraction 1.5h's
Under process conditions, to the extraction and application rate highest of the useful effective component such as polysaccharide in sealwort.Exist to effectively improve sealwort medicinal material
The raw material availability in facial cleanser of the present invention is prepared, manufacture cost of material is reduced.
3 sealwort facial cleanser properties of product contrast test of contrast test example
3.1 acid-base value contrast test of contrast test
Principle：Weakly acidic skin is the basis of skin health, the skin ph value of Asians's health should 4.5-6.5 it
Between, it is average 5.2 or so, it is weakly acidic, the pH value of facial cleanser it is too low or it is excessively high all can skin ambustion, so national Specification
The pH value of facial cleanser is controlled 4.5~8.5.General faintly acid product pH value is about >=5.0 ,≤5.6.Alkalescent product pH value is about
≤ 8.0 ,≤8.5.Neutral products pH value is about 7.0 or so.
Assessment method：With by the cotton rod disinfected a small amount of distilled water is drawn, then dips about 0.5 gram and wash one's face
Milk is coated on PH meters port, reads the pH value of the facial cleanser, record result successively.It is shown in Table 2.
2 Experiment Data Records of table
3.2 cleannes contrast test of contrast test
Principle：The major function of facial cleanser is for cleaning skin.So whether the quality of facial cleanser, first have to see its
Cleaning capacity.This test and appraisal will take simplest hand skin cut method, and make one from the different facial cleansers of market sale
A lateral cleannes comparison, hand cut is most clean after cleaning, then cleaning force is stronger, otherwise cleaning dynamics is then weaker.
Assessment method：With coloured pen on skin of dorsum of hand, two centimetres straight is about with the medium same standardized item of dynamics
Line, dynamics are uniform, it is ensured that the result of 10 cuts is identical.Then with the various brands mildy wash 1g of same aliquot, respectively cleaning stroke
Trace is gently rubbed 20 seconds, is observed evaluating result, is arranged with serial number so that cleannes are ascending, and record successively.It is shown in Table 3.
3 Experiment Data Records of table
3.3 comfort level contrast test of contrast test
Principle：Generally when choosing face cleaning product, consumer can habitually open bottle cap, squeeze out its color from the point of view of one
Pool, quality.It, can be by facial cleanser due to the difference of the substances such as grease, thickener, curing agent, surfactant contained by product
Quality be divided into four major class, white shape, mile, mousse.This experiment will do a test and appraisal by comfort level to product.It is optimum to wash one's face
Milk color and luster wants moderate, too dim to seem coarse, and too glossy then oil base is more.Foam is inadequate compared with few then cleaning force degree, crosses and at most makes
At dry skin.Therefore draw a conclusion after color and luster, quality, the test and appraisal of foaming abundancy degree, breast matter color should be off-white color, after touch
Feel breast matter mildly non-greasy.Meanwhile density is answered moderate, will not be easy to condense into fast, overall feeling is fine and smooth, it is soft, have light
Pool feels the most comfortable when texture is soft and skin contact
Assessment method：Experience product as main point of penetration from the color and luster of facial cleanser breast matter, quality, foaming abundancy degree
Comfort level, and record result.It is shown in Table 4.
4 Experiment Data Records of table
Lasting moisture preserving time, skin repair rate and the antibiotic rate contrast test of 3.4 product of contrast test
Subjects：There are cosmetics at 250 ages 18-40 Sui the people of different degrees of skin allergic lesions symptom
Group.
Test method：According to《Hygienic standards for cosmetics》(GB7918-87) it is detected, 250 subjects are random
It is divided into 3 groups, is denoted as 1 group of experiment, test 2 groups, tests 3 groups and 4 groups of experiment.Wherein, it tests 1 group and uses commercially available common moisturizing reparation
Facial cleanser；Test 2 groups of facial cleansers prepared using comparative example 1 (facial cleanser for changing product formula ratio)；Test 2 groups of uses pair
Facial cleanser (changing washing one's face for product formula ratio) prepared by ratio 2；4 groups are tested using the facial cleanser prepared in comparative example 3 (to change
Become the facial cleanser of step of preparation process) 5 groups of washing one's face with moisturizing repair function containing sealwort prepared using embodiment 3 of experiment
Milk.Lasting moisture preserving time, skin repair rate and the antibiotic rate comparative test result of different product see the table below shown in 5：
Lasting moisture preserving time, skin repair rate and the antibiotic rate comparative test result of 5 product of table
As known from Table 5,5 groups of 2 groups-experiment of experiment is with obvious effects better than 1 group of experiment.Test 5 groups of moisture preserving time longests, bacterium
It is most short to fall total minimum, allergic skin recovery rate highest and allergic skin the reparation time used completely.
To sum up known to performance comparison test result：(1) in terms of PH, sealwort facial cleanser acid-base value and human facial skin's acid
Basicity is adapted, and there is good mildness, long-time service any irritation will not be caused to damage to skin.(2) it is cleaning
In degree test, the cleaning capacity of the facial cleanser of the present invention containing sealwort is medium, therefore will not be due to cleaning capacity deficiency when use
The grease and dust on skin can not be removed, meanwhile, many greases of sauce will not be taken away because cleaning capacity is too strong so that facial flesh
Skin is dried, and the consequences such as peeling, pain are caused；(3) in the test and appraisal of facial cleanser comfort level, sealwort facial cleanser is in paste, has single
Usage amount is convenient for the advantage adjusted；And foaming capacity is strong, has the advantages that foam is thick and solid, fine and smooth；Its color, smell are not used in
The facial cleanser of other addition essential oils, but the medicine with pure natural, no added Chinese medicine sealwort itself is fragrant.
Claims (10)
1. a kind of facial cleanser containing sealwort with moisturizing repair function, which is characterized in that by sealwort extracting solution and facial cleanser matrix,
According to weight 1：15-25 is formulated；Wherein, the facial cleanser matrix includes the raw material group of following weight
At：12-15 parts of butanediol；4-5 parts of pentanediol；4-5 parts of polymer hyaluronic acid；25-35 parts of foaming agent；3-5 parts of trehalose；Urine
It is 4-5 parts plain；3-4 parts of thickener；30-40 parts of water.
2. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 1, which is characterized in that its feature
It is, by sealwort extracting solution and facial cleanser matrix, according to weight 1：15 are formulated；Wherein, the facial cleanser matrix,
Raw material composition including following weight：15 parts of butanediol；5 parts of pentanediol；5 parts of polymer hyaluronic acid；Foaming agent 35
Part；5 parts of trehalose；5 parts of urea；3 parts of thickener；30 parts of water.
3. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 1, which is characterized in that the Huang
Smart extracting solution is made especially by following method：
S1：Clean fresh sealwort is taken, is crushed after slice, 20-80 mesh sieve is crossed, obtains sealwort powder；
S2：Above-mentioned sealwort powder is taken, according to solid-liquid ratio 1：10-20 adds water to mix；
S3：By mixed sealwort powder liquid, refluxing extraction 2 times, each reflux extracting time is that 1-2h extracts to get the sealwort
Liquid.
4. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 3, which is characterized in that step S1
Middle sealwort powder crosses 50-70 mesh sieve.
5. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 3, which is characterized in that step S2
In, the mixed liquor ratio of sealwort powder and water is 1:15.
6. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 3, which is characterized in that step S3
In every time reflux extracting time be 1.5h.
7. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 1, which is characterized in that described
Infusion is amino acid foaming agent, including one or more of ms-11 powder of amino acids foaming agent and No. 2 amino acid foaming agents.
8. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 7, which is characterized in that described
The weight of ms-11 powder of amino acids foaming agent and No. 2 amino acid foaming agents is 2-5:1-2.
9. a kind of method preparing any facial cleansers with moisturizing repair function containing sealwort of claim 1-8, feature
It is, includes the following steps：
A, raw material is classified：It weighs foaming agent, butanediol and pentanediol to be placed in A containers, then weighs polymer hyaluronic acid, urine
Element, trehalose, thickener and water are placed in B containers；
B, the pre-heat treatment：By the raw material in above-mentioned A containers and B containers, it is preheated to 80-90 DEG C respectively；
C, mixing and emulsifying：By the raw material in the raw material and B containers in A containers after preheating, mix while stirring, and be maintained at 80-
90 DEG C of emulsified 10-20min；
D, sealwort extracting solution is added：Mixing speed is reduced, waits for that temperature is down to 60 DEG C, sealwort Aqueous extracts are added according to component proportion,
Uniform stirring stops heating to after 48 DEG C at a slow speed, and after room temperature, bottling has moisturizing to get described containing sealwort
The dairy products of washing one's face of repair function.
10. a kind of preparation method of facial cleanser with moisturizing repair function containing sealwort according to claim 9, feature
It is, in step c, the raw material in the raw material and B containers in A containers after preheating mixes while stirring, and preferably at 85 DEG C
Emulsify 10min.
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