CN108431040B - 利培酮的抗体及其用途 - Google Patents

利培酮的抗体及其用途 Download PDF

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Publication number
CN108431040B
CN108431040B CN201680074144.9A CN201680074144A CN108431040B CN 108431040 B CN108431040 B CN 108431040B CN 201680074144 A CN201680074144 A CN 201680074144A CN 108431040 B CN108431040 B CN 108431040B
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China
Prior art keywords
antibody
risperidone
antigen
binding fragment
sample
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Expired - Fee Related
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CN201680074144.9A
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English (en)
Chinese (zh)
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CN108431040A (zh
Inventor
B.萨卡拉恩
T.R.德科利
T.土布斯
L.科特
M.维利根
P.R.哈斯帕斯拉哥
E.赫利赫兰科
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Janssen Pharmaceutica NV
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Janssen Pharmaceutica NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201680074144.9A 2015-12-17 2016-12-15 利培酮的抗体及其用途 Expired - Fee Related CN108431040B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562268898P 2015-12-17 2015-12-17
US62/268898 2015-12-17
PCT/US2016/066931 WO2017106501A1 (en) 2015-12-17 2016-12-15 Antibodies to risperidone and use thereof

Publications (2)

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CN108431040A CN108431040A (zh) 2018-08-21
CN108431040B true CN108431040B (zh) 2022-07-26

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CN201680074144.9A Expired - Fee Related CN108431040B (zh) 2015-12-17 2016-12-15 利培酮的抗体及其用途

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US (2) US10444250B2 (enrdf_load_stackoverflow)
EP (1) EP3390449A1 (enrdf_load_stackoverflow)
JP (1) JP6949025B2 (enrdf_load_stackoverflow)
CN (1) CN108431040B (enrdf_load_stackoverflow)
AU (1) AU2016372069A1 (enrdf_load_stackoverflow)
CA (1) CA3008809A1 (enrdf_load_stackoverflow)
MA (1) MA44056A (enrdf_load_stackoverflow)
WO (1) WO2017106501A1 (enrdf_load_stackoverflow)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2888284T (pt) * 2012-08-21 2022-11-18 Janssen Pharmaceutica Nv Anticorpos dirigidos contra haptenos de risperidona e a sua utilização
WO2014031603A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to paliperidone haptens and use thereof
EP2887952B1 (en) 2012-08-21 2019-05-15 Janssen Pharmaceutica NV Antibodies to olanzapine haptens and use thereof
ES2870004T3 (es) 2012-08-21 2021-10-26 Janssen Pharmaceutica Nv Anticuerpos contra la risperidona y uso de los mismos
AU2016372069A1 (en) 2015-12-17 2018-06-07 Saladax Biomedical Inc. Antibodies to risperidone and use thereof
CN108368180B (zh) 2015-12-17 2022-07-26 詹森药业有限公司 喹硫平的抗体及其用途
CN112730825B (zh) * 2020-12-17 2022-09-06 北京丹大生物技术有限公司 一种用于检测利培酮和/或9-羟基利培酮的检测试剂和检测试剂盒

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014031630A2 (en) * 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to paliperidone and use thereof
WO2014031635A1 (en) * 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to aripiprazole haptens and use thereof
WO2014031601A1 (en) * 2012-08-21 2014-02-27 Janssen Pharmaceutica Nv Haptens of risperidone and paliperidone
CN104737017A (zh) * 2012-08-21 2015-06-24 奥索临床诊断有限公司 利培酮的抗体及其用途

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EP3390449A1 (en) 2018-10-24
CA3008809A1 (en) 2017-06-22
US20200033370A1 (en) 2020-01-30
US20170176473A1 (en) 2017-06-22
US10444250B2 (en) 2019-10-15
JP6949025B2 (ja) 2021-10-13
WO2017106501A1 (en) 2017-06-22
AU2016372069A1 (en) 2018-06-07
JP2019504013A (ja) 2019-02-14
CN108431040A (zh) 2018-08-21
US10852313B2 (en) 2020-12-01
MA44056A (fr) 2018-10-24

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