DE602004024798D1 - Herstellung von quetiapin - Google Patents
Herstellung von quetiapinInfo
- Publication number
- DE602004024798D1 DE602004024798D1 DE602004024798T DE602004024798T DE602004024798D1 DE 602004024798 D1 DE602004024798 D1 DE 602004024798D1 DE 602004024798 T DE602004024798 T DE 602004024798T DE 602004024798 T DE602004024798 T DE 602004024798T DE 602004024798 D1 DE602004024798 D1 DE 602004024798D1
- Authority
- DE
- Germany
- Prior art keywords
- quetiapine
- preparation
- compound
- discloses
- well
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/16—[b, f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50498103P | 2003-09-23 | 2003-09-23 | |
PCT/FI2004/000560 WO2005028458A1 (en) | 2003-09-23 | 2004-09-23 | Preparation of quetiapine |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004024798D1 true DE602004024798D1 (de) | 2010-02-04 |
Family
ID=34375548
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004024798T Active DE602004024798D1 (de) | 2003-09-23 | 2004-09-23 | Herstellung von quetiapin |
Country Status (9)
Country | Link |
---|---|
US (1) | US7863441B2 (de) |
EP (1) | EP1664007B1 (de) |
JP (1) | JP2007505864A (de) |
AT (1) | ATE452882T1 (de) |
CA (1) | CA2538745A1 (de) |
DE (1) | DE602004024798D1 (de) |
ES (1) | ES2335589T3 (de) |
PT (1) | PT1664007E (de) |
WO (1) | WO2005028458A1 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005028459A1 (en) * | 2003-09-23 | 2005-03-31 | Fermion Oy | Preparation method for quetiapine |
EP1869007A1 (de) | 2005-04-14 | 2007-12-26 | Teva Pharmaceutical Industries Ltd | Verfahren zur herstellung von quetiapinfumaraten |
PT103884A (pt) * | 2006-11-17 | 2008-05-19 | Astrazeneca Ab | Composições de libertação prolongada e métodos para a sua preparação |
WO2009004480A2 (en) | 2007-05-07 | 2009-01-08 | Actavis Group Ptc Ehf | Quetiapine salts and their polymorphs |
AU2009208909A1 (en) | 2008-01-31 | 2009-08-06 | Fermion Oy | A process for the preparation of quetiapine |
WO2010100623A1 (en) | 2009-03-04 | 2010-09-10 | Ranbaxy Laboratories Limited | Process for the preparation of quetiapine fumarate |
CN101891707B (zh) * | 2010-07-29 | 2012-10-17 | 浙江海正药业股份有限公司 | 喹硫平或其可药用盐的制备方法 |
ES2691092T3 (es) | 2012-08-21 | 2018-11-23 | Janssen Pharmaceutica Nv | Anticuerpos contra la risperidona y uso de los mismos |
EP2888284B1 (de) | 2012-08-21 | 2022-07-06 | Janssen Pharmaceutica NV | Antikörper gegen risperidon-haptene und verwendungen davon |
CA2882560C (en) | 2012-08-21 | 2020-10-27 | Ortho-Clinical Diagnostics, Inc. | Haptens of risperidone and paliperidone for use in immunoassays |
AU2013305901B2 (en) | 2012-08-21 | 2017-10-26 | Saladax Biomedical Inc. | Antibodies to olanzapine and use thereof |
US9410972B2 (en) | 2012-08-21 | 2016-08-09 | Janssen Pharmaceutica Nv | Antibodies to quetiapine and use thereof |
CN110054693A (zh) | 2012-08-21 | 2019-07-26 | 詹森药业有限公司 | 喹硫平半抗原的抗体及其用途 |
ES2666000T3 (es) | 2012-08-21 | 2018-04-30 | Janssen Pharmaceutica, N.V. | Anticuerpos para aripiprazol y uso de los mismos |
CN104822660A (zh) | 2012-08-21 | 2015-08-05 | 詹森药业有限公司 | 阿立哌唑半抗原及其在免疫测定中的应用 |
EP3492473A1 (de) * | 2012-08-21 | 2019-06-05 | Janssen Pharmaceutica NV | Haptene von olanzipin |
US9304126B2 (en) * | 2012-08-21 | 2016-04-05 | Janssen Pharmaceutica Nv | Haptens of quetiapine |
US9394354B2 (en) | 2012-08-21 | 2016-07-19 | Janssen Pharmaceutica Nv | Haptens of paliperidone |
AU2013305938B2 (en) | 2012-08-21 | 2017-08-17 | Saladax Biomedical Inc. | Antibodies to paliperidone haptens and use thereof |
CA2882595C (en) | 2012-08-21 | 2019-06-04 | Ortho-Clinical Diagnostics, Inc. | Antibodies to olanzapine haptens and use thereof |
CN104736561B (zh) | 2012-08-21 | 2018-06-12 | 詹森药业有限公司 | 帕潘立酮的抗体及其用途 |
EP2888285B1 (de) | 2012-08-21 | 2024-04-17 | Janssen Pharmaceutica NV | Antikörper gegen aripiprazol-haptene und verwendung davon |
CN103396382B (zh) * | 2013-07-29 | 2015-05-20 | 太仓市茜泾化工有限公司 | 一种喹硫平中间体的制备方法 |
CN104803947A (zh) * | 2015-03-12 | 2015-07-29 | 常州康丽制药有限公司 | 11-(1-哌嗪基)二苯并[b,f][1,4]硫氮杂*富马酸盐的制备方法 |
WO2017106508A1 (en) | 2015-12-17 | 2017-06-22 | Janssen Pharmaceutica Nv | Antibodies to quetiapine and use thereof |
WO2017106501A1 (en) | 2015-12-17 | 2017-06-22 | Janssen Pharmaceutica Nv | Antibodies to risperidone and use thereof |
CN114181172B (zh) * | 2021-12-27 | 2023-12-22 | 浙江苏泊尔制药有限公司 | 一种富马酸喹硫平的高效制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA979441A (en) * | 1967-02-27 | 1975-12-09 | American Cyanamid Company | 11-(piperazinyl) dibenz (b,f) (1,4) oxazepines and analogous thiazepines |
US3539573A (en) * | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
HU227039B1 (en) * | 2000-01-25 | 2010-05-28 | Egis Gyogyszergyar Nyilvanosan | New process for the production of quetiapine and intermediates therefor |
DK1818325T3 (da) * | 2001-04-16 | 2010-05-31 | Schering Corp | 3,4-di-substituerede cyklobuten-1,2-dioner som CXC-chemokin receptorligander |
ES2223294B2 (es) * | 2003-08-08 | 2005-10-01 | Vita Cientifica, S.L. | Procedimiento de preparacion de un compuesto farmaceuticamente activo. |
WO2005028459A1 (en) * | 2003-09-23 | 2005-03-31 | Fermion Oy | Preparation method for quetiapine |
-
2004
- 2004-09-23 WO PCT/FI2004/000560 patent/WO2005028458A1/en active Application Filing
- 2004-09-23 ES ES04767074T patent/ES2335589T3/es active Active
- 2004-09-23 EP EP04767074A patent/EP1664007B1/de active Active
- 2004-09-23 JP JP2006526653A patent/JP2007505864A/ja not_active Ceased
- 2004-09-23 US US10/572,409 patent/US7863441B2/en not_active Expired - Fee Related
- 2004-09-23 PT PT04767074T patent/PT1664007E/pt unknown
- 2004-09-23 CA CA002538745A patent/CA2538745A1/en not_active Abandoned
- 2004-09-23 AT AT04767074T patent/ATE452882T1/de active
- 2004-09-23 DE DE602004024798T patent/DE602004024798D1/de active Active
Also Published As
Publication number | Publication date |
---|---|
EP1664007B1 (de) | 2009-12-23 |
WO2005028458A1 (en) | 2005-03-31 |
ATE452882T1 (de) | 2010-01-15 |
US7863441B2 (en) | 2011-01-04 |
CA2538745A1 (en) | 2005-03-31 |
PT1664007E (pt) | 2010-02-15 |
US20070111987A1 (en) | 2007-05-17 |
EP1664007A1 (de) | 2006-06-07 |
JP2007505864A (ja) | 2007-03-15 |
ES2335589T3 (es) | 2010-03-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |