DE602004024798D1 - Herstellung von quetiapin - Google Patents

Herstellung von quetiapin

Info

Publication number
DE602004024798D1
DE602004024798D1 DE602004024798T DE602004024798T DE602004024798D1 DE 602004024798 D1 DE602004024798 D1 DE 602004024798D1 DE 602004024798 T DE602004024798 T DE 602004024798T DE 602004024798 T DE602004024798 T DE 602004024798T DE 602004024798 D1 DE602004024798 D1 DE 602004024798D1
Authority
DE
Germany
Prior art keywords
quetiapine
preparation
compound
discloses
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004024798T
Other languages
English (en)
Inventor
Petteri Rummakko
Soini Huhta
Arne Grumann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fermion Oy
Original Assignee
Fermion Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fermion Oy filed Critical Fermion Oy
Publication of DE602004024798D1 publication Critical patent/DE602004024798D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16—[b, f]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE602004024798T 2003-09-23 2004-09-23 Herstellung von quetiapin Active DE602004024798D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50498103P 2003-09-23 2003-09-23
PCT/FI2004/000560 WO2005028458A1 (en) 2003-09-23 2004-09-23 Preparation of quetiapine

Publications (1)

Publication Number Publication Date
DE602004024798D1 true DE602004024798D1 (de) 2010-02-04

Family

ID=34375548

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004024798T Active DE602004024798D1 (de) 2003-09-23 2004-09-23 Herstellung von quetiapin

Country Status (9)

Country Link
US (1) US7863441B2 (de)
EP (1) EP1664007B1 (de)
JP (1) JP2007505864A (de)
AT (1) ATE452882T1 (de)
CA (1) CA2538745A1 (de)
DE (1) DE602004024798D1 (de)
ES (1) ES2335589T3 (de)
PT (1) PT1664007E (de)
WO (1) WO2005028458A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005028459A1 (en) * 2003-09-23 2005-03-31 Fermion Oy Preparation method for quetiapine
EP1869007A1 (de) 2005-04-14 2007-12-26 Teva Pharmaceutical Industries Ltd Verfahren zur herstellung von quetiapinfumaraten
PT103884A (pt) * 2006-11-17 2008-05-19 Astrazeneca Ab Composições de libertação prolongada e métodos para a sua preparação
WO2009004480A2 (en) 2007-05-07 2009-01-08 Actavis Group Ptc Ehf Quetiapine salts and their polymorphs
AU2009208909A1 (en) 2008-01-31 2009-08-06 Fermion Oy A process for the preparation of quetiapine
WO2010100623A1 (en) 2009-03-04 2010-09-10 Ranbaxy Laboratories Limited Process for the preparation of quetiapine fumarate
CN101891707B (zh) * 2010-07-29 2012-10-17 浙江海正药业股份有限公司 喹硫平或其可药用盐的制备方法
ES2691092T3 (es) 2012-08-21 2018-11-23 Janssen Pharmaceutica Nv Anticuerpos contra la risperidona y uso de los mismos
EP2888284B1 (de) 2012-08-21 2022-07-06 Janssen Pharmaceutica NV Antikörper gegen risperidon-haptene und verwendungen davon
CA2882560C (en) 2012-08-21 2020-10-27 Ortho-Clinical Diagnostics, Inc. Haptens of risperidone and paliperidone for use in immunoassays
AU2013305901B2 (en) 2012-08-21 2017-10-26 Saladax Biomedical Inc. Antibodies to olanzapine and use thereof
US9410972B2 (en) 2012-08-21 2016-08-09 Janssen Pharmaceutica Nv Antibodies to quetiapine and use thereof
CN110054693A (zh) 2012-08-21 2019-07-26 詹森药业有限公司 喹硫平半抗原的抗体及其用途
ES2666000T3 (es) 2012-08-21 2018-04-30 Janssen Pharmaceutica, N.V. Anticuerpos para aripiprazol y uso de los mismos
CN104822660A (zh) 2012-08-21 2015-08-05 詹森药业有限公司 阿立哌唑半抗原及其在免疫测定中的应用
EP3492473A1 (de) * 2012-08-21 2019-06-05 Janssen Pharmaceutica NV Haptene von olanzipin
US9304126B2 (en) * 2012-08-21 2016-04-05 Janssen Pharmaceutica Nv Haptens of quetiapine
US9394354B2 (en) 2012-08-21 2016-07-19 Janssen Pharmaceutica Nv Haptens of paliperidone
AU2013305938B2 (en) 2012-08-21 2017-08-17 Saladax Biomedical Inc. Antibodies to paliperidone haptens and use thereof
CA2882595C (en) 2012-08-21 2019-06-04 Ortho-Clinical Diagnostics, Inc. Antibodies to olanzapine haptens and use thereof
CN104736561B (zh) 2012-08-21 2018-06-12 詹森药业有限公司 帕潘立酮的抗体及其用途
EP2888285B1 (de) 2012-08-21 2024-04-17 Janssen Pharmaceutica NV Antikörper gegen aripiprazol-haptene und verwendung davon
CN103396382B (zh) * 2013-07-29 2015-05-20 太仓市茜泾化工有限公司 一种喹硫平中间体的制备方法
CN104803947A (zh) * 2015-03-12 2015-07-29 常州康丽制药有限公司 11-(1-哌嗪基)二苯并[b,f][1,4]硫氮杂*富马酸盐的制备方法
WO2017106508A1 (en) 2015-12-17 2017-06-22 Janssen Pharmaceutica Nv Antibodies to quetiapine and use thereof
WO2017106501A1 (en) 2015-12-17 2017-06-22 Janssen Pharmaceutica Nv Antibodies to risperidone and use thereof
CN114181172B (zh) * 2021-12-27 2023-12-22 浙江苏泊尔制药有限公司 一种富马酸喹硫平的高效制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA979441A (en) * 1967-02-27 1975-12-09 American Cyanamid Company 11-(piperazinyl) dibenz (b,f) (1,4) oxazepines and analogous thiazepines
US3539573A (en) * 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
HU227039B1 (en) * 2000-01-25 2010-05-28 Egis Gyogyszergyar Nyilvanosan New process for the production of quetiapine and intermediates therefor
DK1818325T3 (da) * 2001-04-16 2010-05-31 Schering Corp 3,4-di-substituerede cyklobuten-1,2-dioner som CXC-chemokin receptorligander
ES2223294B2 (es) * 2003-08-08 2005-10-01 Vita Cientifica, S.L. Procedimiento de preparacion de un compuesto farmaceuticamente activo.
WO2005028459A1 (en) * 2003-09-23 2005-03-31 Fermion Oy Preparation method for quetiapine

Also Published As

Publication number Publication date
EP1664007B1 (de) 2009-12-23
WO2005028458A1 (en) 2005-03-31
ATE452882T1 (de) 2010-01-15
US7863441B2 (en) 2011-01-04
CA2538745A1 (en) 2005-03-31
PT1664007E (pt) 2010-02-15
US20070111987A1 (en) 2007-05-17
EP1664007A1 (de) 2006-06-07
JP2007505864A (ja) 2007-03-15
ES2335589T3 (es) 2010-03-30

Similar Documents

Publication Publication Date Title
ATE452882T1 (de) Herstellung von quetiapin
CY1113578T1 (el) 2,3-διυδρο-6-νιτροϊμιδαζο 2,1 -b-οξαζολια
DK1474406T3 (da) Disubstituerede thiazolylcarboxanilider samt deres anvendelse som mikrobicider
BR0307432A (pt) Difluormetiltiazolilcarboxanilidas
CY1110064T1 (el) Παραγωγα φαινυλ-πιπεραζινης ως αναστολεις επαναπροσληψης σεροτονινης
HK1096549A1 (en) Imidazopyridine-derivatives as inducible no-synthase inhibitors
ATE441630T1 (de) Substituierte cyclopenten-verbindungen
HK1159614A1 (en) Caspase inhibitors and uses thereof
CO5690637A2 (es) Tiazol-(bi) cicloalquil-carboxanilidas
MY148242A (en) Process for making trans-1-((1r,3s)-6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine
ATE398121T1 (de) Neue synthese von irbesartan
EA200600485A1 (ru) Способ получения производных 2-оксо-1-пирролидина
HK1096548A1 (en) Imidazopyridine-derivatives as inductible no-synthase inhibitors
TR200503401T1 (tr) Kuetiapin (Quetiapine) Fumarat'ın yeni polimorfları
NO20040388L (no) Fremgangsmåte for fremstilling av beraprost og salter derav, samt forbindelser som er mellomprodukter i fremgangsmåten
NO20016151L (no) Fremstilling av substituerte piperidin-4-oner
DE602004031129D1 (de) Verfahren zur herstellung von quetiapin
DK1206452T3 (da) Fremgangsmåde til fremstilling af benzoperhydro-isoindolforbindelser
ATE377594T1 (de) Oxathiincarboxamide
WO2004096828A3 (fr) Nouveau procede et intermediaires de preparation de composes 19-nor-steroïdes
WO2005054175A3 (en) New process for the preparation of nitrooxyderivatives of paracetamol
MXPA05003881A (es) Preparacion de compuestos triazospiro.
DE50312447D1 (de) Verfahren zur herstellung von 4,6-dichlor-5-fluorpyrimidin
EA200970863A1 (ru) Способ и промежуточные соединения для получения арзоксифена
ATE417055T1 (de) Steroid modifizierte solatriosen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition