CN108403972A - 一种治疗鸡大肠杆菌病中草药制剂的制作方法 - Google Patents
一种治疗鸡大肠杆菌病中草药制剂的制作方法 Download PDFInfo
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Abstract
本发明公开了一种治疗鸡大肠杆菌病中草药制剂的制作方法,包括以下原料及重量分数:金银花5‑17份、连翘6‑18份、麻黄15‑32份、黄连10‑20份、黄柏10‑20份、蒲公英15‑20份、赤芍15‑20份、牡丹皮10‑20份、淡竹叶10‑15份、黄芩10‑15份、鱼腥草10‑15份、野菊花10‑15份、夏枯草15‑20份、生石膏10‑15份、防风18‑40份、羌活17‑35份、独活20‑42份、柴胡9‑17份、前胡11‑25份、川芎13‑27份、枳壳8‑17份、茯苓9‑20份、桔梗7‑16份、甘草6‑14份。本发明是采用原料选用纯中药产品,可以做成各种剂型如散剂、口服液、颗粒剂、片剂、丸剂、膏剂等,能够有效地避免抗奶、药物残留和食品安全问题,适宜在畜牧生产中进行推广,并且可以高效的治疗鸡大肠杆菌,同时可以提高鸡的免疫力。
Description
技术领域
本发明涉及兽医医药加工技术领域,尤其是一种治疗鸡大肠杆菌病中草药制剂的制作方法。
背景技术
我国是一个畜禽大国。据统计,我国每年因各类禽病引起的家禽死亡率高达15~20%,经济损失达数十亿元。在整个禽类疾病中,传染病占80%,普通病占20%。且发病禽的种类也不断增多,禽病种类复杂,新病不断出现,80年代以来,以鸡大肠杆菌病、鸡白痢等病常见,其广泛流行,严重危害禽类养殖。
鸡大肠杆菌病是由大肠杆菌引起的一种传染病,该病可引起不同日龄及品种的鸡发病。临床上,以排黄白色稀便、败血症、肝周炎、气囊炎和心包炎为主要特征。该病常与其他疾病并发或继发,对养鸡业危害十分严重。由于大肠杆菌的血清型非常多,使用菌苗免疫效果不理想,所以药物治疗成为控制该病的主要手段。
目前,治疗鸡大肠杆菌的药物居多,但是多数药物成本高、易复发、疗效不够理想的缺陷,针对这些问题,在这里我们提出一种治疗鸡大肠杆菌病中草药制剂的制作方法。
发明内容
本发明针对现有的治疗大肠杆菌配方等技术上的不足,提供了一种治疗鸡大肠杆菌病中草药制剂的制作方法。
本发明为解决上述技术不足,采用改性的技术方案,一种治疗鸡大肠杆菌病中草药制剂的制作方法,包括以下原料及重量分数:金银花5-17份、连翘6-18份、麻黄15-32份、黄连10-20份、黄柏10-20份、蒲公英15-20份、赤芍15-20份、牡丹皮10-20份、淡竹叶10-15份、黄芩10-15份、鱼腥草10-15份、野菊花10-15份、夏枯草15-20份、生石膏10-15份、防风18-40份、羌活17-35份、独活20-42份、柴胡9-17份、前胡11-25份、川芎13-27份、枳壳8-17份、茯苓9-20份、桔梗7-16份、甘草6-14份。
作为本发明的进一步优选方式,还包括以下原料及重量分数:金银花5份、连翘6份、麻黄15份、黄连10份、黄柏10份、蒲公英15份、赤芍15份、牡丹皮10份、淡竹叶10份、黄芩10份、鱼腥草10份、野菊花10份、夏枯草15-20份、生石膏10份、防风18份、羌活17份、独活20份、柴胡9份、前胡11份、川芎13份、枳壳8份、茯苓9份、桔梗7份、甘草6份。
作为本发明的进一步优选方式,还包括以下原料及重量分数:金银花17份、连翘18份、麻黄32份、黄连20份、黄柏20份、蒲公英20份、赤芍20份、牡丹皮20份、淡竹叶15份、黄芩15份、鱼腥草15份、野菊花15份、夏枯草20份、生石膏15份、防风40份、羌活35份、独活42份、柴胡17份、前胡25份、川芎27份、枳壳17份、茯苓20份、桔梗16份、甘草14份。
作为本发明的进一步优选方式,制作工艺步骤如下:
S1,将金银花、连翘、麻黄、黄连、黄柏、蒲公英、赤芍、牡丹皮、淡竹叶、黄芩、鱼腥草分别蒸馏提取挥发油,蒸馏后的水溶液另用容器进行收集;
S2,配制渗漉液,将蒸馏液体加入乙醇调节成含乙醇量35%的溶剂作为渗漉溶剂,对黄柏、蒲公英、赤芍、牡丹皮的药渣进行渗漉收集漉液,然后进行减压回收乙醇;
S3,将野菊花、夏枯草、生石膏、防风、羌活、独活、柴胡、前胡、川芎、枳壳、茯苓、桔梗、甘草加水煮三次,过滤,合并滤液,与漉液合并静置,过滤;
S4,将步骤S3和步骤S1的溶液,进行充分均匀搅拌,加热温度控制在65-85℃,控制20-45min,即得产品;
S5,将加工后的液体进行收膏,然后进行浸膏,然后利用PET塑瓶进行罐封,注入的溶剂可略微大于标示量,最后包装纸盒中,完成加工。
作为本发明的进一步优选方式,步骤S1,还包括在加工前,需要对原材料进行前处理,所述前处理包括对中药进行挑选、清洗、切制、炮灸、烘干、粉碎和筛分。
作为本发明的进一步优选方式,步骤S3中,煎煮三次,第一次30min,第二次15min小时,第三次20min。
作为本发明的进一步优选方式,步骤S4中,材料混合完成后,利用搅拌设备进行搅拌,搅拌转速设为1200-1800r/min。
作为本发明的进一步优选方式,步骤S5中,在收膏过程中,后续可持续高温加热消毒,持续5-12分钟,高温消毒后,再进行紫外线消毒。
本发明是采用原料选用纯中药产品,可以做成各种剂型如散剂、口服液、颗粒剂、片剂、丸剂、膏剂等,能够有效地避免抗奶、药物残留和食品安全问题,适宜在畜牧生产中进行推广,并且可以高效的治疗鸡大肠杆菌,同时可以提高鸡的免疫力。
具体实施方式
下面将结合本发明实施例中,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
本发明提供一种技术方案:一种治疗鸡大肠杆菌病中草药制剂的制作方法,包括以下原料及重量分数:金银花5-17份、连翘6-18份、麻黄15-32份、黄连10-20份、黄柏10-20份、蒲公英15-20份、赤芍15-20份、牡丹皮10-20份、淡竹叶10-15份、黄芩10-15份、鱼腥草10-15份、野菊花10-15份、夏枯草15-20份、生石膏10-15份、防风18-40份、羌活17-35份、独活20-42份、柴胡9-17份、前胡11-25份、川芎13-27份、枳壳8-17份、茯苓9-20份、桔梗7-16份、甘草6-14份。
还包括以下原料及重量分数:金银花5份、连翘6份、麻黄15份、黄连10份、黄柏10份、蒲公英15份、赤芍15份、牡丹皮10份、淡竹叶10份、黄芩10份、鱼腥草10份、野菊花10份、夏枯草15-20份、生石膏10份、防风18份、羌活17份、独活20份、柴胡9份、前胡11份、川芎13份、枳壳8份、茯苓9份、桔梗7份、甘草6份。
还包括以下原料及重量分数:金银花17份、连翘18份、麻黄32份、黄连20份、黄柏20份、蒲公英20份、赤芍20份、牡丹皮20份、淡竹叶15份、黄芩15份、鱼腥草15份、野菊花15份、夏枯草20份、生石膏15份、防风40份、羌活35份、独活42份、柴胡17份、前胡25份、川芎27份、枳壳17份、茯苓20份、桔梗16份、甘草14份。
制作工艺步骤如下:
S1,将金银花、连翘、麻黄、黄连、黄柏、蒲公英、赤芍、牡丹皮、淡竹叶、黄芩、鱼腥草分别蒸馏提取挥发油,蒸馏后的水溶液另用容器进行收集;
S2,配制渗漉液,将蒸馏液体加入乙醇调节成含乙醇量35%的溶剂作为渗漉溶剂,对黄柏、蒲公英、赤芍、牡丹皮的药渣进行渗漉收集漉液,然后进行减压回收乙醇;
S3,将野菊花、夏枯草、生石膏、防风、羌活、独活、柴胡、前胡、川芎、枳壳、茯苓、桔梗、甘草加水煮三次,过滤,合并滤液,与漉液合并静置,过滤;
S4,将步骤S3和步骤S1的溶液,进行充分均匀搅拌,加热温度控制在65-85℃,控制20-45min,即得产品;
S5,将加工后的液体进行收膏,然后进行浸膏,然后利用PET塑瓶进行罐封,注入的溶剂可略微大于标示量,最后包装纸盒中,完成加工。
步骤S1,还包括在加工前,需要对原材料进行前处理,所述前处理包括对中药进行挑选、清洗、切制、炮灸、烘干、粉碎和筛分。
步骤S3中,煎煮三次,第一次30min,第二次15min小时,第三次20min。
步骤S4中,材料混合完成后,利用搅拌设备进行搅拌,搅拌转速设为1200-1800r/min。
步骤S5中,在收膏过程中,后续可持续高温加热消毒,持续5-12分钟,高温消毒后,再进行紫外线消毒。
综上,本发明是采用原料选用纯中药产品,可以做成各种剂型如散剂、口服液、颗粒剂、片剂、丸剂、膏剂等,能够有效地避免抗奶、药物残留和食品安全问题,适宜在畜牧生产中进行推广,并且可以高效的治疗鸡大肠杆菌,同时可以提高鸡的免疫力。
最后应说明的是:以上所述仅为本发明的优选实施例而已,并不用于限制本发明,尽管参照前述实施例对本发明进行了详细的说明,对于本领域的技术人员来说,其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分技术特征进行等同替换。凡在本发明的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。
Claims (8)
1.一种治疗鸡大肠杆菌病中草药制剂的制作方法,其特征在于,包括以下原料及重量分数:金银花5-17份、连翘6-18份、麻黄15-32份、黄连10-20份、黄柏10-20份、蒲公英15-20份、赤芍15-20份、牡丹皮10-20份、淡竹叶10-15份、黄芩10-15份、鱼腥草10-15份、野菊花10-15份、夏枯草15-20份、生石膏10-15份、防风18-40份、羌活17-35份、独活20-42份、柴胡9-17份、前胡11-25份、川芎13-27份、枳壳8-17份、茯苓9-20份、桔梗7-16份、甘草6-14份。
2.根据权利要求1所述的一种治疗鸡大肠杆菌病中草药制剂的制作方法,其特征在于,还包括以下原料及重量分数:金银花5份、连翘6份、麻黄15份、黄连10份、黄柏10份、蒲公英15份、赤芍15份、牡丹皮10份、淡竹叶10份、黄芩10份、鱼腥草10份、野菊花10份、夏枯草15-20份、生石膏10份、防风18份、羌活17份、独活20份、柴胡9份、前胡11份、川芎13份、枳壳8份、茯苓9份、桔梗7份、甘草6份。
3.根据权利要求1所述的一种治疗鸡大肠杆菌病中草药制剂的制作方法,其特征在于,还包括以下原料及重量分数:金银花17份、连翘18份、麻黄32份、黄连20份、黄柏20份、蒲公英20份、赤芍20份、牡丹皮20份、淡竹叶15份、黄芩15份、鱼腥草15份、野菊花15份、夏枯草20份、生石膏15份、防风40份、羌活35份、独活42份、柴胡17份、前胡25份、川芎27份、枳壳17份、茯苓20份、桔梗16份、甘草14份。
4.根据权利要求1所述的一种治疗鸡大肠杆菌病中草药制剂的制作方法,其特征在于,制作工艺步骤如下:
S1,将金银花、连翘、麻黄、黄连、黄柏、蒲公英、赤芍、牡丹皮、淡竹叶、黄芩、鱼腥草分别蒸馏提取挥发油,蒸馏后的水溶液另用容器进行收集;
S2,配制渗漉液,将蒸馏液体加入乙醇调节成含乙醇量35%的溶剂作为渗漉溶剂,对黄柏、蒲公英、赤芍、牡丹皮的药渣进行渗漉收集漉液,然后进行减压回收乙醇;
S3,将野菊花、夏枯草、生石膏、防风、羌活、独活、柴胡、前胡、川芎、枳壳、茯苓、桔梗、甘草加水煮三次,过滤,合并滤液,与漉液合并静置,过滤;
S4,将步骤S3和步骤S1的溶液,进行充分均匀搅拌,加热温度控制在65-85℃,控制20-45min,即得产品;
S5,将加工后的液体进行收膏,然后进行浸膏,然后利用PET塑瓶进行罐封,注入的溶剂可略微大于标示量,最后包装纸盒中,完成加工。
5.根据权利要求4所述的一种治疗鸡大肠杆菌病中草药制剂的制作方法的加工工艺,其特征在于,步骤S1,还包括在加工前,需要对原材料进行前处理,所述前处理包括对中药进行挑选、清洗、切制、炮灸、烘干、粉碎和筛分。
6.根据权利要求4所述的一种治疗鸡大肠杆菌病中草药制剂的制作方法的加工工艺,其特征在于,步骤S3中,煎煮三次,第一次30min,第二次15min小时,第三次20min。
7.根据权利要求4所述的一种治疗鸡大肠杆菌病中草药制剂的制作方法的加工工艺,其特征在于,步骤S4中,材料混合完成后,利用搅拌设备进行搅拌,搅拌转速设为1200-1800r/min。
8.根据权利要求4所述的一种治疗鸡大肠杆菌病中草药制剂的制作方法的加工工艺,其特征在于,步骤S5中,在收膏过程中,后续可持续高温加热消毒,持续5-12分钟,高温消毒后,再进行紫外线消毒。
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