CN108379384A - A kind of kidney-tonifying traditional Chinese medicine composition and preparation method thereof - Google Patents

A kind of kidney-tonifying traditional Chinese medicine composition and preparation method thereof Download PDF

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CN108379384A
CN108379384A CN201810378671.XA CN201810378671A CN108379384A CN 108379384 A CN108379384 A CN 108379384A CN 201810378671 A CN201810378671 A CN 201810378671A CN 108379384 A CN108379384 A CN 108379384A
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罗成
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Guizhou Miao Cao Tang Bio Technology Co Ltd
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Abstract

The invention belongs to technical field of traditional Chinese medicines, especially a kind of kidney-tonifying traditional Chinese medicine composition and preparation method thereof, use Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, Rhizoma Chuanxiong, Cortex Eucommiae, penis otariae, gekko, cynomorium songaricum, matrimony vine and excessive rains sheep suddenly for raw material, pass through rational proportion design, so that the effect of forming collaboration between drug, and then kidney-yin deficiency and kidney-yang deficiency can be effectively treated, and it is significant in efficacy, cure rate reaches 80% or more;Kidney-reinforcing drug of the present invention is using balanced human's negative and positive as principle, for the purpose of kidney yin kidney yang giving young employees remedial-courses in general knowledge and vocational skills, realizes treating both manifestation and root cause of disease, and has the characteristics that low dose, rapid-action, short treating period, cure rate are high, has no toxic side effect.

Description

A kind of kidney-tonifying traditional Chinese medicine composition and preparation method thereof
Technical field
The invention belongs to technical field of traditional Chinese medicines, especially a kind of kidney-tonifying traditional Chinese medicine composition and preparation method thereof.
Background technology
It is insufficient that kidney deficiency refers to kidney vital essence negative and positive.The type of kidney deficiency has very much, and one of the most common is kidney-yin deficiency, kidney-yang deficiency; Kidney-yin deficiency cardinal symptom is soreness and weakness of waist and knees, two skelasthenias, dysphoria, dizziness and tinnitus, body become thin, insomnia and dreamful sleep, cheekbone red tide Heat, night sweat, dry throat, impotence in male or penis ultroerection do not fall, sexual hyperesthesia, premature ejaculation of passing out semen, women through less, Amenorrhea, uterine bleeding, infertile, urine It is short helvolus;Kidney-yang deficiency male spiritlessness and weakness, lassitude, vigor be low, fatiguability;Chilly is cold, cold limbs, body hair It is heavy;Soreness of waist and knee joint, back crymodynia, muscles and bones wither soft;Hypogona dism, premature ejaculation, is susceptible to suffer from prostatitis etc. at impotence;It is clear abundant urine, remaining Drip not to the utmost, oliguria or night pollakiuria;Hearing or tinnitus;Failure of memory, drowsiness, dreaminess, spontaneous perspiration;It is susceptible to suffer from pain in the back, joint Pain etc.;It is susceptible to suffer from osteoporosis, cervical spondylosis, lumbar vertebra disease etc.;Void is breathed short, cough and asthma gurgling weith sputum;Morning diarrhea or constipation;Body is floating It is swollen, below waist more so, edema of lower extremity;Underbelly draws testis falling inflation pain or scrotum and shrinks, meet it is cold what for, heat is then delayed;Beard and hair It is easy to fall off, early white;Body puffiness is thin thin;Being reflected in face, then color is bluish white unglazed or dark;Kidney-yang deficiency women spiritlessness and weakness, essence God is depressed, vigor is low, fatiguability;Chilly is cold, cold limbs, body hair are heavy;Soreness of waist and knee joint, back crymodynia, muscles and bones wither soft; Sexual hypoesthesia, uterus cold infertile, clear and thin leucorrhea;Qi depression to blood stasis causes punching to appoint obstructed, menstrual disorder or capable and unsmooth, frequent small abdominal distension Bitterly;Menstrual period is delayed, measures less, color is dark, has block or dysmenorrhoea;Uterus, ovary, the easy myogenic tumor of breast, tumour, hyperplasia etc.;It is susceptible to suffer from and secretes The diseases such as urinary system infection, gynaecological imflammation;Easily leading to climacteric shifts to an earlier date;Void is breathed, and short, tongue is white fat big or has indentation;Hearing Or tinnitus, failure of memory;It is susceptible to suffer from pain in the back, arthralgia etc.;It is susceptible to suffer from osteoporosis, cervical spondylosis, lumbar vertebra disease etc.;Morning diarrhea, Or constipation;Body puffiness is thin thin;Pale complexion is dark, the skin problems such as easily raw chloasma, acne, acne, allergy.
Currently, the drug of existing treatment kidney deficiency is varied in the market, largely there is that the course for the treatment of is long, and curative effect is undesirable, The problems such as palliative.
Invention content
In order to solve the above technical problems existing in the prior art, kidney-yin deficiency, kidney yang being treated the present invention provides a kind of Empty kidney-tonifying traditional Chinese medicine composition and preparation method.
It is realized especially by following manner
A kind of kidney-tonifying traditional Chinese medicine composition, raw material are in parts by weight:5~15 parts of Radix Angelicae Sinensis, 1~10 part of safflower, radix rehmanniae preparata 10~ 20 parts, 5~15 parts of Rhizoma Chuanxiong, 15~25 parts of Cortex Eucommiae, 10~30 parts of penis otariae, 10~30 parts of gekko, 25~35 parts of cynomorium songaricum, matrimony vine 15 ~25 parts, 5~15 parts suddenly of excessive rains sheep.
The raw material is in parts by weight:8~12 parts of Radix Angelicae Sinensis, 4~7 parts of safflower, 13~16 parts of radix rehmanniae preparata, 8~12 parts of Rhizoma Chuanxiong, 18~23 parts of Cortex Eucommiae, 15~25 parts of penis otariae, 15~25 parts of gekko, 28~32 parts of cynomorium songaricum, 18~23 parts of matrimony vine, excessive rains sheep suddenly 8~ 12 parts.
The raw material is calculated as with weight point:10 parts of Radix Angelicae Sinensis, 5 parts of safflower, 15 parts of radix rehmanniae preparata, 10 parts of Rhizoma Chuanxiong, 20 parts of Cortex Eucommiae, fur seal 20 parts of whip, 20 parts of gekko, 30 parts of cynomorium songaricum, 20 parts of matrimony vine, 10 parts suddenly of excessive rains sheep.
The preparation method of the Chinese medicine composition of above-mentioned kidney tonifying, includes the following steps:Above-mentioned each taste Chinese medicine is measured according to formula, After crushing respectively, 40~60 mesh sieve is crossed, adds after mixing or does not add medically acceptable auxiliary material, required dosage form is made.
The dosage form is vina, tablet, electuary or honeyed bolus.
In each taste Chinese medicine, cynomorium songaricum, matrimony vine, Cortex Eucommiae mix after crushing respectively, and adjustment moisture is 25~35%, is stirred After mixing uniformly, it is inoculated with the fermenting agent of its weight 1~3%, it is 3~5d of fermentation process under the conditions of 30~40 DEG C to be placed in temperature, is obtained To tunning be placed in 60~80 DEG C under the conditions of dry 1~2h, then be ground into powder.
The fermenting agent is saccharomycete and acetic acid bacteria according to 1:The weight proportion of (0.5~1) mixes.
By the way that cynomorium songaricum, matrimony vine, Cortex Eucommiae mixed fermentation are handled, the regulation and control of combining with fermentation technological parameter so that cynomorium songaricum, Chinese holly Under the action of saccharomycete and lactic acid bacteria, active ingredient composition changes for Qi, Cortex Eucommiae, and then mixed with other compositions in raw material When conjunction, the interaction between drug can be promoted, and then improve the therapeutic effect to Patients with Kidney Deficiency Type.
Advantageous effect
Kidney-reinforcing drug of the present invention uses Radix Angelicae Sinensis, safflower, radix rehmanniae preparata, Rhizoma Chuanxiong, Cortex Eucommiae, penis otariae, gekko, cynomorium songaricum, matrimony vine and excessive rains sheep It is suddenly raw material, passes through rational proportion design so that forms the effect of collaboration between drug, and then can effectively treat kidney yin Empty and kidney-yang deficiency, and it is significant in efficacy, and cure rate reaches 80% or more;Kidney-reinforcing drug of the present invention using balanced human's negative and positive as principle, For the purpose of kidney yin kidney yang giving young employees remedial-courses in general knowledge and vocational skills, treating both manifestation and root cause of disease, and low, rapid-action, short treating period, cure rate height, nontoxic pair with dose are realized The characteristics of effect.
Specific implementation mode
Tuberculosis specific embodiment is limited technical scheme of the present invention is further below, but claimed Range describes made by being not only limited to.
Embodiment 1
A kind of kidney-tonifying traditional Chinese medicine composition, raw material are in parts by weight:Radix Angelicae Sinensis 5g, safflower 1g, radix rehmanniae preparata 10g, Rhizoma Chuanxiong 5g, Cortex Eucommiae 15g, penis otariae 10g, gekko 10g, cynomorium songaricum 25g, matrimony vine 15g, excessive rains sheep 5g suddenly;
The preparation method of above-mentioned kidney-tonifying traditional Chinese medicine composition, includes the following steps:Above-mentioned each taste Chinese medicine is measured according to formula, point Not Fen Sui after, cross 40 mesh sieve, electuary is made after mixing.
Embodiment 2
A kind of kidney-tonifying traditional Chinese medicine composition, raw material are in parts by weight:Radix Angelicae Sinensis 15g, safflower 10g, radix rehmanniae preparata 20g, Rhizoma Chuanxiong 15g, Cortex Eucommiae 25g, penis otariae 30g, gekko 30g, cynomorium songaricum 35g, matrimony vine 25g, excessive rains sheep 15g suddenly;
The preparation method of above-mentioned kidney-tonifying traditional Chinese medicine composition, includes the following steps:Above-mentioned each taste Chinese medicine is measured according to formula, point Not Fen Sui after, cross 60 mesh sieve, starch is added after mixing, it is tabletted.
Embodiment 3
A kind of kidney-tonifying traditional Chinese medicine composition, raw material are in parts by weight:Radix Angelicae Sinensis 8g, safflower 4g, radix rehmanniae preparata 13g, Rhizoma Chuanxiong 8g, Cortex Eucommiae 18g, penis otariae 25g, gekko 15g, cynomorium songaricum 28g, matrimony vine 18g, excessive rains sheep 8g suddenly;
The preparation method of above-mentioned kidney-tonifying traditional Chinese medicine composition, includes the following steps:Above-mentioned each taste Chinese medicine is measured according to formula, point Not Fen Sui after, cross 40 mesh sieve, after mixing add honey honeyed bolus is made.
Embodiment 4
A kind of kidney-tonifying traditional Chinese medicine composition, raw material are in parts by weight:Radix Angelicae Sinensis 12g, safflower 7g, radix rehmanniae preparata 16g, Rhizoma Chuanxiong 12g, Du Secondary 23g, penis otariae 15g, gekko 25g, cynomorium songaricum 32g, matrimony vine 23g, excessive rains sheep 12g suddenly;
The preparation method of above-mentioned kidney-tonifying traditional Chinese medicine composition, includes the following steps:Above-mentioned each taste Chinese medicine is measured according to formula, point Not Fen Sui after, cross 60 mesh sieve, be added to after mixing in the rice wine tank for filling 1000ml, impregnate 20~25d, filter to obtain vina.
Embodiment 5
A kind of kidney-tonifying traditional Chinese medicine composition, raw material are in parts by weight:Radix Angelicae Sinensis 11g, safflower 6g, radix rehmanniae preparata 14g, Rhizoma Chuanxiong 12g, Du Secondary 18g, penis otariae 18g, gekko 18g, cynomorium songaricum 31g, matrimony vine 22g, excessive rains sheep 11g suddenly;
The preparation method of above-mentioned kidney-tonifying traditional Chinese medicine composition, includes the following steps:Above-mentioned each taste Chinese medicine is measured according to formula, point Not Fen Sui after, cross 50 mesh sieve, electuary is made after mixing;
In each taste Chinese medicine, cynomorium songaricum, matrimony vine, Cortex Eucommiae mix after crushing respectively, and adjustment moisture is 25%, and stirring is equal After even, it is inoculated with the fermenting agent of its weight 1%, it is fermentation process 3d under the conditions of 30 DEG C to be placed in temperature, and obtained tunning is set The dry 1h under the conditions of 60 DEG C, then it is ground into powder.
The fermenting agent is saccharomycete and acetic acid bacteria according to 1:0.5 weight proportion mixes.
Embodiment 6
A kind of kidney-tonifying traditional Chinese medicine composition, raw material are in parts by weight:Radix Angelicae Sinensis 12g, safflower 4g, radix rehmanniae preparata 16g, Rhizoma Chuanxiong 8g, Du Secondary 23g, penis otariae 20g, gekko 25g, cynomorium songaricum 28g, matrimony vine 23g, excessive rains sheep 8g suddenly;
The preparation method of above-mentioned kidney-tonifying traditional Chinese medicine composition, includes the following steps:Above-mentioned each taste Chinese medicine is measured according to formula, point Not Fen Sui after, cross 40 mesh sieve, dextrin is added after mixing, it is tabletted;
In each taste Chinese medicine, cynomorium songaricum, matrimony vine, Cortex Eucommiae mix after crushing respectively, and adjustment moisture is 35%, and stirring is equal After even, it is inoculated with the fermenting agent of its weight 3%, it is fermentation process 5d under the conditions of 40 DEG C to be placed in temperature, and obtained tunning is set The dry 2h under the conditions of 80 DEG C, then it is ground into powder.
The fermenting agent is saccharomycete and acetic acid bacteria according to 1:1 weight proportion mixes.
Embodiment 7
A kind of kidney-tonifying traditional Chinese medicine composition, raw material are in parts by weight:Radix Angelicae Sinensis 10g, safflower 5g, radix rehmanniae preparata 15g, Rhizoma Chuanxiong 10g, Du Secondary 20g, penis otariae 20g, gekko 20g, cynomorium songaricum 30g, matrimony vine 20g, excessive rains sheep 10g suddenly;
The preparation method of above-mentioned kidney-tonifying traditional Chinese medicine composition, includes the following steps:Above-mentioned each taste Chinese medicine is measured according to formula, point Not Fen Sui after, cross 60 mesh sieve, electuary is made after mixing;
In each taste Chinese medicine, cynomorium songaricum, matrimony vine, Cortex Eucommiae mix after crushing respectively, and adjustment moisture is 30%, and stirring is equal After even, it is inoculated with the fermenting agent of its weight 2%, it is fermentation process 4d under the conditions of 35 DEG C to be placed in temperature, and obtained tunning is set The dry 1.5h under the conditions of 75 DEG C, then it is ground into powder.
The fermenting agent is saccharomycete and acetic acid bacteria according to 1:0.7 weight proportion mixes.
Test example 1
The kidney-tonifying traditional Chinese medicine composition that the present invention is prepared respectively with 1~embodiment of embodiment 7 is done clinical efficacy and is summarized as follows: One, general data:This Chinese medicine composition is applied to clinical observation case 256, man 137, female 119, age 25~65 In year, it is randomly divided into 7 groups;
It is used as diagnostic criteria by following index:1. ache of the spinal column;2. soreness of waist and knee or talagia;3. alopecia or tooth pine It is dynamic;4. tinnitus or deafness;5. urine retention or the urinary incontinence;6. sexual deterioration, infertile or sterile;
Curative effect determinate standard:1. fully recovering:Symptom completely disappears, be discontinued after 3 months without repeatedly;2. effective:Symptom is apparent to be obtained To alleviation;3. effectively:Symptom is mitigated, but occasional aggravates;4. invalid:Symptom is without alleviating or have exacerbation;
Therapeutic effect such as the following table 1:
Table 1
Group Number of cases Recovery from illness number Effective number Significant figure Invalid number Cure rate %
Embodiment 1 35 29 2 2 2 82.9
Embodiment 2 42 35 2 3 2 83.3
Embodiment 3 36 31 1 2 2 86.1
Embodiment 4 38 32 2 1 3 84.2
Embodiment 5 32 28 1 2 1 87.5
Embodiment 6 39 34 2 2 1 87.2
Embodiment 7 34 31 1 1 1 91.2
By upper table test result it is found that drug prepared by the present invention program there is significant treatment to imitate treatment Patients with Kidney Deficiency Type Fruit, and cure rate reaches 80% or more;The cure rate effect of especially embodiment 5,6,7 is preferable, due to in raw material Medicine carries out fermentation process so that the pharmacological property of Chinese medicine is improved, therefore improves the therapeutic effect to Patients with Kidney Deficiency Type.
Model case:
Case is 1.:Hu, man, 29 years old, since half a year, four limbs were swollen, and dizzy powerless, insomnia and dreamful sleep, frequent micturition was once repeatedly controlled It treats, but ineffective;It is diagnosed as:Kidney deficiency, takes drug 3d prepared by Chinese medicine composition of the present invention, and symptom is eased, takes After 5d, all symptoms disappear, and reach healing, by the observation of half a year, do not occur the case where recurrence.
Case is 2.:Zhao, man, 46 years old, have a surplus within 1 year with kidney deficiency illness, after because occur dizziness, nausea, edema, the soreness of waist Bitterly, shortness of breath and fatigue and be admitted to hospital, the state of an illness continues to develop after being admitted to hospital, and renal function continues to deteriorate, occur it is murky, drowsiness;By taking hair After bright drug 7d, symptom is eased, and continuously takes 21d, and all symptoms disappear, and recovery from illness, follow-up is so far without recurrence.
It is important to point out that, above example and test example are only limitted to do further technical scheme of the present invention herein Elaboration and understanding, should not be understood as it is further to technical scheme of the present invention limited, what those skilled in the art made The innovation and creation of non-protruding essential characteristics and marked improvement still fall within the protection category of the present invention.

Claims (8)

1. a kind of kidney-tonifying traditional Chinese medicine composition, which is characterized in that raw material is in parts by weight:5~15 parts of Radix Angelicae Sinensis, 1~10 part of safflower, 10~20 parts of radix rehmanniae preparata, 5~15 parts of Rhizoma Chuanxiong, 15~25 parts of Cortex Eucommiae, 10~30 parts of penis otariae, 10~30 parts of gekko, cynomorium songaricum 25~35 Part, 15~25 parts of matrimony vine, 5~15 parts suddenly of excessive rains sheep.
2. kidney-tonifying traditional Chinese medicine composition as described in claim 1, which is characterized in that the raw material is in parts by weight:Radix Angelicae Sinensis 8~12 Part, 4~7 parts of safflower, 13~16 parts of radix rehmanniae preparata, 8~12 parts of Rhizoma Chuanxiong, 18~23 parts of Cortex Eucommiae, 15~25 parts of penis otariae, gekko 15~25 Part, 28~32 parts of cynomorium songaricum, 18~23 parts of matrimony vine, 8~12 parts suddenly of excessive rains sheep.
3. kidney-tonifying traditional Chinese medicine composition as claimed in claim 1 or 2, which is characterized in that the raw material is calculated as with weight point:Radix Angelicae Sinensis 10 Part, 5 parts of safflower, 15 parts of radix rehmanniae preparata, 10 parts of Rhizoma Chuanxiong, 20 parts of Cortex Eucommiae, 20 parts of penis otariae, 20 parts of gekko, 30 parts of cynomorium songaricum, 20 parts of matrimony vine, 10 parts suddenly of excessive rains sheep.
4. the preparation method of kidney-tonifying traditional Chinese medicine composition as described in any one of claims 1 to 3, which is characterized in that including following step Suddenly:Above-mentioned each taste Chinese medicine is measured according to formula, after crushing respectively, 40~60 mesh sieve is crossed, adds or do not add medically after mixing Required dosage form is made in acceptable auxiliary material.
5. the preparation method of kidney-tonifying traditional Chinese medicine composition as claimed in claim 4, which is characterized in that the dosage form be vina, tablet, Electuary or honeyed bolus.
6. the preparation method of kidney-tonifying traditional Chinese medicine composition as claimed in claim 4, which is characterized in that in each taste Chinese medicine, cynomorium songaricum, Matrimony vine, Cortex Eucommiae mix after crushing respectively, and adjustment moisture is 25~35%, after stirring evenly, is inoculated with its weight 1~3% Fermenting agent, it is 3~5d of fermentation process under the conditions of 30~40 DEG C to be placed in temperature, and obtained tunning is placed in 60~80 DEG C of conditions 1~2h of lower drying, then it is ground into powder.
7. the preparation method of kidney-tonifying traditional Chinese medicine composition as claimed in claim 6, which is characterized in that the fermenting agent is saccharomycete With acetic acid bacteria according to 1:The weight proportion of (0.5~1) mixes.
8. kidney-tonifying traditional Chinese medicine composition is used for the treatment of kidney-yin deficiency, kidney-yang deficiency as described in any one of claims 1 to 3.
CN201810378671.XA 2018-04-25 2018-04-25 A kind of kidney-tonifying traditional Chinese medicine composition and preparation method thereof Pending CN108379384A (en)

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Application publication date: 20180810