CN104623550B - The Chinese medicine for the treatment of sciatica - Google Patents

Abstract

The invention provides a kind of Chinese medicine being used for the treatment of sciatica, its crude drug comprises Rhizoma Drynariae, the Cortex Eucommiae, Rhizoma Cibotii, Caulis Spatholobi, Myrrha, Rhizoma Curcumae Longae, Fructus Mume, Radix Et Caulis Acanthopanacis Senticosi, Herba Visci, Herba Thesii Longifolii, Radix Campanumoeae, pittosporm root, wind and cold grass, Herba Tagetis Patulae, Conyza japonica, Radix Gentianae Macrophyllae, Radix Morindae Officinalis, Semen Cuscutae, Ramulus Cinnamomi and Herba Centipedae.This Chinese medicine coordinates traditional acupuncture treatment sciatica to play synergism, and significantly improve curative effect, more obviously better than simple acupuncture treatment effect, the course for the treatment of is shorter.

Description

The Chinese medicine for the treatment of sciatica

Technical field

The present invention relates to technical field of Chinese medicine, particularly relate to a kind of Chinese medicine being used for the treatment of sciatica.

Background technology

Sciatica refers to, in sciatic nerve path and areal area thereof, pain occurs, and is common peripheral nerve disease.Primary disease is mainly in person between twenty and fifty, and male is more.Clinically be divided into constitutional and Secondary cases 2 kinds: the morbidity of primary sciatica with catch cold, moist, damage and infection etc. relevant, caused by the adjacent tissue pathological changes generation mechanical pressure that Secondary Sciatic Pain is nervous pathway or adhesion.Clinical main manifestations is side waist leg paroxysmal or rest pain, by outside on rear side of buttocks, thigh, after shank and foot generation radioactivity, can burn sample or acupuncture sample pain, increase the weight of during action.Primary sciatica onset is acute or subacute outbreak, and Chang Yin is affected by the cold wet and brings out.

Motherland's medical science returns main " arthromyodynia " category it.Numbness is the obstructed meaning of impatency, allly can cause QI and blood impatency, and blockage of meridian person's its reason of all can falling ill is as follows: 1, enter outside wind-cold damp pathogen.As " Plain Questions numbness opinion " section is pointed out: " so-called numbness person, respectively with at that time, reinfection in the wet gas of wind and cold also ", " wet three gas of wind and cold are mixed extremely, combined into numbness also ".2, ferritic is weak, and striae of the skin and muscles being loose battalion Wei Bugu, exopathogen is taken advantage of a weak point in opponent's defence and invaded.As " Prescriptions for Succouring the Sick numbness " section is pointed out: " all because body is empty, space between skin and muscles is empty, and dampness of having a cold forms numbness also ".3, ferritic preponderance of YANG QI, inside has intrinsic heat, during being invaded by exogenous pathogen, easily enters inner heat-transformation.Namely as so-called in " Lei Zheng Zhi Cai gout " " cold-damp wind Yu Biyin divides, and then attacks pain through heat for a long time ".In addition arthromyodynia is prolonged does not heal, and pathogen stops up resistance, and QI and blood is solidifying cold, and blood fortune is not smooth, and venation is obstructed, can cause blood stasis symptom.The pathogeny of arthromyodynia is summarised as in sum: invade outside wind-cold damp pathogen, multiple abscess meridians joint, QI-blood circulation is not smooth and be arthromyodynia, but there is the difference of body constitution rise and fall of yin and yang, course of disease length, void can be held under the arm, hold heat under the arm, hold the cards such as the stasis of blood under the arm, treatment on dispelling cold by warming the meridian, expelling wind and removing dampness, blood-activating and qi-promoting, dissipating blood stasis for subsidence of swelling, muscles and tendons relaxing to alleviate pain for principle.

Adopt Chinese Medicine and Clavicular traditional acupuncture treatment sciatica provided by the invention to play synergism, significantly improve curative effect, more obviously better than simple acupuncture treatment effect, the course for the treatment of is shorter.

Summary of the invention

Technical problem to be solved by this invention is to provide a kind of Chinese medicine being used for the treatment of sciatica, and it coordinates traditional acupuncture treatment sciatica to play synergism, and significantly improve curative effect, more obviously better than simple acupuncture treatment effect, the course for the treatment of is shorter.

For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine being used for the treatment of sciatica, its crude drug comprises Rhizoma Drynariae, the Cortex Eucommiae, Rhizoma Cibotii, Caulis Spatholobi, Myrrha, Rhizoma Curcumae Longae, Fructus Mume, Radix Et Caulis Acanthopanacis Senticosi, Herba Visci, Herba Thesii Longifolii, Radix Campanumoeae, pittosporm root, wind and cold grass, Herba Tagetis Patulae, Conyza japonica, Radix Gentianae Macrophyllae, Radix Morindae Officinalis, Semen Cuscutae, Ramulus Cinnamomi and Herba Centipedae.

Wherein, in described Chinese medicine, the weight portion of each raw material is respectively Rhizoma Drynariae 55 weight portion ~ 65 weight portion, the Cortex Eucommiae 25 weight portion ~ 35 weight portion, Rhizoma Cibotii 35 weight portion ~ 45 weight portion, Caulis Spatholobi 25 weight portion ~ 35 weight portion, Myrrha 25 weight portion ~ 35 weight portion, Rhizoma Curcumae Longae 30 weight portion ~ 40 weight portion, Fructus Mume 5 weight portion ~ 15 weight portion, Radix Et Caulis Acanthopanacis Senticosi 25 weight portion ~ 35 weight portion, Herba Visci 35 weight portion ~ 45 weight portion, Herba Thesii Longifolii 15 weight portion ~ 25 weight portion, Radix Campanumoeae 20 weight portion ~ 30 weight portion, pittosporm root 20 weight portion ~ 30 weight portion, wind and cold grass 15 weight portion ~ 25 weight portions, Herba Tagetis Patulae 10 weight portion ~ 20 weight portion, Conyza japonica 15 weight portion ~ 25 weight portion, Radix Gentianae Macrophyllae 25 weight portion ~ 35 weight portion, Radix Morindae Officinalis 25 weight portion ~ 35 weight portion, Semen Cuscutae 20 weight portion ~ 30 weight portion, Ramulus Cinnamomi 20 weight portion ~ 30 weight portion and Herba Centipedae 10 weight portion ~ 20 weight portion.

Wherein, in described Chinese medicine, the weight portion of each crude drug is respectively Rhizoma Drynariae 58 weight portion ~ 62 weight portion, the Cortex Eucommiae 28 weight portion ~ 32 weight portion, Rhizoma Cibotii 38 weight portion ~ 42 weight portion, Caulis Spatholobi 28 weight portion ~ 32 weight portion, Myrrha 28 weight portion ~ 32 weight portion, Rhizoma Curcumae Longae 33 weight portion ~ 37 weight portion, Fructus Mume 8 weight portion ~ 12 weight portion, Radix Et Caulis Acanthopanacis Senticosi 28 weight portion ~ 32 weight portion, Herba Visci 38 weight portion ~ 42 weight portion, Herba Thesii Longifolii 18 weight portion ~ 22 weight portion, Radix Campanumoeae 23 weight portion ~ 27 weight portion, pittosporm root 23 weight portion ~ 27 weight portion, wind and cold grass 18 weight portion ~ 22 weight portions, Herba Tagetis Patulae 13 weight portion ~ 17 weight portion, Conyza japonica 18 weight portion ~ 22 weight portion, Radix Gentianae Macrophyllae 28 weight portion ~ 32 weight portion, Radix Morindae Officinalis 28 weight portion ~ 32 weight portion, Semen Cuscutae 23 weight portion ~ 27 weight portion, Ramulus Cinnamomi 23 weight portion ~ 27 weight portion and Herba Centipedae 13 weight portion ~ 17 weight portion.

Wherein, in described Chinese medicine, the weight portion of each crude drug is respectively Rhizoma Drynariae 60 weight portion, the Cortex Eucommiae 30 weight portion, Rhizoma Cibotii 40 weight portion, Caulis Spatholobi 30 weight portion, Myrrha 30 weight portion, Rhizoma Curcumae Longae 35 weight portion, Fructus Mume 10 weight portion, Radix Et Caulis Acanthopanacis Senticosi 30 weight portion, Herba Visci 40 weight portion, Herba Thesii Longifolii 20 weight portion, Radix Campanumoeae 25 weight portion, pittosporm root 25 weight portion, wind and cold grass 20 weight portions, Herba Tagetis Patulae 15 weight portion, Conyza japonica 20 weight portion, Radix Gentianae Macrophyllae 30 weight portion, Radix Morindae Officinalis 30 weight portion, Semen Cuscutae 25 weight portion, Ramulus Cinnamomi 25 weight portion and Herba Centipedae 15 weight portion.

Wherein, described extract oral uses.

Wherein, described Chinese drug preparation becomes soup decoct and tablet.

Present invention also offers the preparation method of above-mentioned Chinese medicine, when this Chinese drug preparation becomes soup decoct, concrete preparation process is as follows,

Shredded respectively by each crude drug, the product of chopping mixes according to above-mentioned weight portion, obtains mixture, add the water relative to this mixture 3 ~ 5 times of quality, soak 1 hour, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, and filtering residue adds the water relative to mixture 2 ~ 4 times of quality again, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, the filtrate mixing of twice, concentrating under reduced pressure, removes part aqueous solvent, obtains the soup decoct of 1g/ml crude drug concentration.

Present invention also offers the preparation method of above-mentioned Chinese medicine, when this Chinese drug preparation becomes tablet, concrete preparation process is as follows:

The first step, shredded respectively by each crude drug, the product of chopping mixes according to above-mentioned weight portion, obtains mixture, add the water relative to this mixture 3 ~ 5 times of quality, soak 1 hour, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, filtering residue adds the water relative to mixture 2 ~ 4 times of quality again, is heated to boiling, decocts 2 ~ 3 hours, decoction liquor is filtered, the filtrate mixing of twice, concentrating under reduced pressure, removes aqueous solvent, obtain and get dry extract, be ground into powder, cross 100 mesh sieves, obtain the fine powder that sieves;

Second step, gets 200g fine powder, adds starch 40-60g and microcrystalline Cellulose 60-80g, mixing, granulates, adds Magnesium Stearate proper quantity, and mixing, is pressed into 1000, film coating, obtains final product.

Beneficial effect of the present invention:

The invention provides the Chinese medicine being used for the treatment of sciatica, it coordinates traditional acupuncture treatment sciatica to play synergism, and significantly improve curative effect, more obviously better than simple acupuncture treatment effect, the course for the treatment of is shorter.

Detailed description of the invention

The invention provides a kind of Chinese medicine being used for the treatment of sciatica, its crude drug comprises Rhizoma Drynariae, the Cortex Eucommiae, Rhizoma Cibotii, Caulis Spatholobi, Myrrha, Rhizoma Curcumae Longae, Fructus Mume, Radix Et Caulis Acanthopanacis Senticosi, Herba Visci, Herba Thesii Longifolii, Radix Campanumoeae, pittosporm root, wind and cold grass, Herba Tagetis Patulae, Conyza japonica, Radix Gentianae Macrophyllae, Radix Morindae Officinalis, Semen Cuscutae, Ramulus Cinnamomi and Herba Centipedae.

Described Chinese medicine is only made up of above-mentioned raw materials medicine further.

In described Chinese medicine, the weight portion of each raw material is respectively Rhizoma Drynariae 55 weight portion ~ 65 weight portion, the Cortex Eucommiae 25 weight portion ~ 35 weight portion, Rhizoma Cibotii 35 weight portion ~ 45 weight portion, Caulis Spatholobi 25 weight portion ~ 35 weight portion, Myrrha 25 weight portion ~ 35 weight portion, Rhizoma Curcumae Longae 30 weight portion ~ 40 weight portion, Fructus Mume 5 weight portion ~ 15 weight portion, Radix Et Caulis Acanthopanacis Senticosi 25 weight portion ~ 35 weight portion, Herba Visci 35 weight portion ~ 45 weight portion, Herba Thesii Longifolii 15 weight portion ~ 25 weight portion, Radix Campanumoeae 20 weight portion ~ 30 weight portion, pittosporm root 20 weight portion ~ 30 weight portion, wind and cold grass 15 weight portion ~ 25 weight portions, Herba Tagetis Patulae 10 weight portion ~ 20 weight portion, Conyza japonica 15 weight portion ~ 25 weight portion, Radix Gentianae Macrophyllae 25 weight portion ~ 35 weight portion, Radix Morindae Officinalis 25 weight portion ~ 35 weight portion, Semen Cuscutae 20 weight portion ~ 30 weight portion, Ramulus Cinnamomi 20 weight portion ~ 30 weight portion and Herba Centipedae 10 weight portion ~ 20 weight portion.

Further preferably, in described Chinese medicine, the weight portion of each crude drug is respectively Rhizoma Drynariae 58 weight portion ~ 62 weight portion, the Cortex Eucommiae 28 weight portion ~ 32 weight portion, Rhizoma Cibotii 38 weight portion ~ 42 weight portion, Caulis Spatholobi 28 weight portion ~ 32 weight portion, Myrrha 28 weight portion ~ 32 weight portion, Rhizoma Curcumae Longae 33 weight portion ~ 37 weight portion, Fructus Mume 8 weight portion ~ 12 weight portion, Radix Et Caulis Acanthopanacis Senticosi 28 weight portion ~ 32 weight portion, Herba Visci 38 weight portion ~ 42 weight portion, Herba Thesii Longifolii 18 weight portion ~ 22 weight portion, Radix Campanumoeae 23 weight portion ~ 27 weight portion, pittosporm root 23 weight portion ~ 27 weight portion, wind and cold grass 18 weight portion ~ 22 weight portions, Herba Tagetis Patulae 13 weight portion ~ 17 weight portion, Conyza japonica 18 weight portion ~ 22 weight portion, Radix Gentianae Macrophyllae 28 weight portion ~ 32 weight portion, Radix Morindae Officinalis 28 weight portion ~ 32 weight portion, Semen Cuscutae 23 weight portion ~ 27 weight portion, Ramulus Cinnamomi 23 weight portion ~ 27 weight portion and Herba Centipedae 13 weight portion ~ 17 weight portion.

Most preferably, in described Chinese medicine, the weight portion of each crude drug is respectively Rhizoma Drynariae 60 weight portion, the Cortex Eucommiae 30 weight portion, Rhizoma Cibotii 40 weight portion, Caulis Spatholobi 30 weight portion, Myrrha 30 weight portion, Rhizoma Curcumae Longae 35 weight portion, Fructus Mume 10 weight portion, Radix Et Caulis Acanthopanacis Senticosi 30 weight portion, Herba Visci 40 weight portion, Herba Thesii Longifolii 20 weight portion, Radix Campanumoeae 25 weight portion, pittosporm root 25 weight portion, wind and cold grass 20 weight portions, Herba Tagetis Patulae 15 weight portion, Conyza japonica 20 weight portion, Radix Gentianae Macrophyllae 30 weight portion, Radix Morindae Officinalis 30 weight portion, Semen Cuscutae 25 weight portion, Ramulus Cinnamomi 25 weight portion and Herba Centipedae 15 weight portion.

Rhizoma Drynariae: bitter in the mouth, warm in nature, enter liver, kidney channel, there is invigorating the kidney and strengthening the bones, continuous effect of hindering pain relieving, for soreness of waist and knee joint of suffering from a deficiency of the kidney, flaccidity and weakness of the lower limbs, the hepatic and renal YIN deficiency, empty positive rising and the deafness and tinnitus that causes, odontoseisis pain or gingival hemorrhage, asthenia of both the spleen and kidney and cause the cards such as chronic diarrhea chronic dysentery.

The Cortex Eucommiae: sweet in the mouth, micro-pungent, warm in nature, enters liver, kidney channel, has blood pressure lowering, invigorating the liver and kidney, bone and muscle strengthening, the effect of antiabortive gas, for caused by liver and kidney deficiency, card see dizzy, soreness of waist and knee joint, muscles and bones flaccidity are weak; Instability of kidney QI, frequent micturition or dripping urination, uncontrolled urination are itched, sexual impotence, anemia of pregnant woman are weak, frequent fetal movement or waist pendant pain; The cards such as chronic joint diseases, bone tuberculosis, dysmenorrhea, dysfunctional uterine bleeding, chronic pelvic inflammatory disease.

Rhizoma Cibotii: bitter in the mouth, sweet, warm in nature, enter liver, kidney channel, have wind-damp dispelling, invigorating the liver and kidney, the effect of strong waist knee joint, for soreness of the waist and knees, arthralgia, Qu Li is unfavorable, insufficiency of kidney-YANG, frequent urination and enuresis, emission and spermatorrhea, the cards such as leukorrhagia.

Caulis Spatholobi: latin name spatholobicaulis, bitter in the mouth, sweet, warm in nature, enter liver, kidney channel, there is blood vessel dilating, enrich blood and invigorate blood circulation, regulating menstruation, the effect of relaxing muscles and tendons and activating QI and blood in the collateral, there is obvious inhibitory action to platelet aggregation, promote animal kidney and the total phosphorus metabolism in uterus, be mainly used in treating the menoxenia that blood deficiency has silt, limbs pain is meciless, the card such as soreness of the waist and knees, pain.

Myrrha: acrid in the mouth, hardship, property is put down, and GUIXIN, liver, spleen channel, have dissipating blood stasis analgesic therapy, and effect of detumescence and promoting granulation, cures mainly obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, rheumatic arthralgia, traumatic injury, the cards such as carbuncle skin infection.

Rhizoma Curcumae Longae: latin name curcumaelongaerhizoma, bitter in the mouth, pungent, warm in nature, enter Liver Channel, there is removing blood stasis circulation of qi promoting, effect of inducing menstruation to relieve menalgia, twinge for the breast side of body, amenorrhea, lump in the abdomen, rheumatism shoulder arm pain, the cards such as tumbling and swelling

Fructus Mume: bitter in the mouth, acid, puckery, warm in nature, enters liver, lung, spleen, large intestine channel, has and astringe the lung, astringing intestine to stop diarrhea, hemostasis, the effect of promoting the production of body fluid, be used for the treatment of chronic dysentery more than, damp-heat dysentery, have blood in stool, hematuria, the card such as snowslide.

Radix Et Caulis Acanthopanacis Senticosi: be the root of studies on plants of Acanthopanax Miq. in Araliaceae Radix Et Caulis Acanthopanacis Senticosi, rhizome or stem and leaf, latin name AcanthopanacisSenticosiRadixetRhizomaseuCaulis, acrid in the mouth, hardship, micro-sweet, warm in nature, enter spleen, kidney, heart channel, there is replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization, effect of expelling wind and removing dampness, soft for anemofrigid-damp arthralgia, lumbocrural pain, muscles and bones flaccidity, be slow in action, the card such as body weakness with emaciation is weak, traumatic injury, fracture, edema, beriberi, uncontrolled urination are itched.

Herba Visci: bitter in the mouth, sweet, property is put down.Return liver, kidney channel, have relaxing muscles and tendons and activating QI and blood in the collateral, effect of promoting blood circulation to remove blood stasis, cures mainly frequent fetal movement, vaginal bleeding during pregnancy hematochezia, bones and muscles pain, limbs contracture, aching pain in waist and back, the cards such as traumatic injury.

Herba Thesii Longifolii: for Santalaceae Thesium plant comes into leaves Herba Thesii, the herb of dew post Herba Thesii or root, acrid in the mouth, micro-hardship, cool in nature, there is heat clearing away of inducing sweat, expelling wind and relieving convulsion, cure mainly flu, heatstroke, sural spasm, infantile pneumonia, the cards such as infantile convulsion.

Radix Campanumoeae: latin name radixcampanumoeajavanicae is the root of campanulaceae leopard platymiscium Campanumoea javanica and leopard, sweet in the mouth, property is put down, and returns lung, spleen channel, has invigorating the spleen and benefiting QI, tonifying the lung and stopping cough, effect of stimulating milk secretion, cure mainly the empty internal injury of labor, the deficiency of vital energy is weak, cardiopalmus, hyperhidrosis, diarrhea due to hypofunction of the spleen, leucorrhea, milk is rare, the cards such as insufficiency of the spleen cough.

Pittosporm root: bitter in the mouth, pungent, warm in nature, have activating collaterals to relieve pain, heart-calming kidney-nourishing, effect of removing toxic substances, cures mainly rheumatic arthralgia, fracture, stomachache, insomnia, seminal emission, the cards such as venom.

Wind and cold grass: be the herb of Primulaceae Lysimachia plant L. congestiflora Hesms, there is expelling wind and cold, preventing phlegm from forming and stopping coughing, detoxification and promoting urination, removing food stagnancy calculus removing effect, cure mainly headche due to wind-cold, cough ant phlegm, laryngopharynx swelling and pain, jaundice, Biliary Calculi, lithangiuria, infantile malnutrition, the cards such as venom.

Herba Tagetis Patulae: be the herb of Compositae plants of tagetes species Herba Tagetis Patulae, bitter in the mouth, property is put down, and have clearing away heat-damp and promoting diuresis, effect of cough-relieving pain relieving, cures mainly upper respiratory tract infection, dysentery, cough, pertussis, toothache, acute conjunctivitis due to pathogenic windfire, the cards such as mastitis.

Conyza japonica: bitter in the mouth, pungent, cold in nature, have clearing away heat to alleviate pain, effect of dispelling pathogenic wind and eliminating phlegm, cures mainly laryngitis, pneumonia, laryngopharynx swelling and pain, the cards such as tonsillitis.

Radix Gentianae Macrophyllae: latin name GentianaeMacrophyllaeRadix, acrid in the mouth, hardship, cold nature, returns stomach warp, Liver Channel, gallbladder meridian, have wind-damp dispelling, relaxing muscles and tendons network, effect of clearind deficient heat, cures mainly rheumatic arthralgia, the contracture of muscle arteries and veins, the cards such as joint is ached, afternoon fever, infantile malnutrition heating.

Radix Morindae Officinalis: latin name MorindaeOfficinalisRadix, acrid in the mouth, sweet, slightly warm in nature, enter liver, kidney channel, there is effect of kidney-replenishing, bone and muscle strengthening, wind-damp dispelling, for impotence due to deficiency of the kidney, seminal emission premature ejaculation, few abdomen cold type of pain, cold womb is infertile, the cards such as the muscles and bones flaccidity caused by deficiency of the liver and kindey is soft, chills and pain of the waist and kness.

Semen Cuscutae: sweet in the mouth, pungent, property is put down, and enters liver,kidney,spleen warp, has the kidney invigorating and essence nourishing, the effect of nourishing the liver to improve visual acuity, be mainly used in the sexual impotence of insufficiency of kidney-YANG, seminal emission premature ejaculation, frequent micturition, dizziness and tinnitus; To suffer from a deficiency of the kidney pain in the lumbar region, married woman's leukorrhagia, nausea is solid; The binocular of both liver and kidney deficiency, deficiency of liver-blood is dim-sighted, blurring of vision; The loose stool stomachache of asthenia of both the spleen and kidney, the cards such as aqueous-grainy diarrhea.

Extract oral provided by the invention uses, and preparation method conveniently can be prepared into various peroral dosage form, preferably be prepared into soup decoct and tablet.

When this Chinese drug preparation becomes soup decoct, concrete preparation process is as follows:

Shredded respectively by each crude drug, the product of chopping mixes according to above-mentioned weight portion, obtains mixture, add the water relative to this mixture 3 ~ 5 times of quality, soak 1 hour, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, and filtering residue adds the water relative to mixture 2 ~ 4 times of quality again, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, the filtrate mixing of twice, concentrating under reduced pressure, removes part aqueous solvent, obtains the soup decoct of 1g/ml crude drug concentration.

When this Chinese drug preparation becomes tablet, concrete preparation process is as follows:

The first step, shredded respectively by each crude drug, the product of chopping mixes according to above-mentioned weight portion, obtains mixture, add the water relative to this mixture 3 ~ 5 times of quality, soak 1 hour, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, filtering residue adds the water relative to mixture 2 ~ 4 times of quality again, is heated to boiling, decocts 2 ~ 3 hours, decoction liquor is filtered, the filtrate mixing of twice, concentrating under reduced pressure, removes aqueous solvent, obtain and get dry extract, be ground into powder, cross 100 mesh sieves, obtain the fine powder that sieves;

Second step, gets 200g fine powder, adds starch 40-60g and microcrystalline Cellulose 60-80g, mixing, granulates, adds Magnesium Stearate proper quantity, and mixing, is pressed into 1000, film coating, obtains final product.

Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.

Soup decoct 1

By Rhizoma Drynariae 60g, Cortex Eucommiae 30g, Rhizoma Cibotii 40g, Caulis Spatholobi 30g, Myrrha 30g, Rhizoma Curcumae Longae 35g, Fructus Mume 10g, Radix Et Caulis Acanthopanacis Senticosi 30g, Herba Visci 40g, Herba Thesii Longifolii 20g, Radix Campanumoeae 25g, pittosporm root 25g, wind and cold grass 20g, Herba Tagetis Patulae 15g, Conyza japonica 20g, Radix Gentianae Macrophyllae 30g, Radix Morindae Officinalis 30g, Semen Cuscutae 25g, Ramulus Cinnamomi 25g and Herba Centipedae 15g shreds respectively, the product of chopping mixes, obtain mixture, add the water of 2.2kg, soak 1 hour, be heated to boiling, decoct 3 hours, decoction liquor is filtered, filtering residue adds the water of 1.6kg again, be heated to boiling, decoct 3 hours, decoction liquor is filtered, the filtrate mixing of twice, concentrating under reduced pressure, remove part aqueous solvent, obtain the soup decoct 1 of 1g/ml crude drug concentration.

Toxicology test

40 SD rats, by body weight random packet, often organize 10, male and female half and half, carry out acute toxicity test by decoction liquor 1 administration prepared by all oral for above-mentioned rat embodiment 1, dosage is only 10.0ml/, there is not any toxic reaction in result, to observation post administration 7 days, all chickens of result are strong deposited, its activity, diet, hair, Excreta are no abnormal, have no toxic reaction.To chicken place post mortem, its main organs observes Non Apparent Abnormality.

Get SD rat 10, male and female half and half, long term administration in 8 months, carries out long term toxicity test, result shows that the indexs such as all rat general status, growth promoter, routine blood test, Liver and kidney function are showed no abnormal change, and histopathology and gross necropsy also have no pathological change.

Toxicity test proves, the not toxic effect of this medicine and untoward reaction, clinical practice is safe and reliable.

Soup decoct 2

By Rhizoma Drynariae 58g, Cortex Eucommiae 28g, Rhizoma Cibotii 38g, Caulis Spatholobi 28g, Myrrha 28g, Rhizoma Curcumae Longae 33g, Fructus Mume 8g, Radix Et Caulis Acanthopanacis Senticosi 28g, Herba Visci 38g, Herba Thesii Longifolii 18g, Radix Campanumoeae 23g, pittosporm root 23g, wind and cold grass 18g, Herba Tagetis Patulae 13g, Conyza japonica 18g, Radix Gentianae Macrophyllae 28g, Radix Morindae Officinalis 28g, Semen Cuscutae 23g, Ramulus Cinnamomi 23g and Herba Centipedae 13g shreds respectively, the product of chopping mixes, obtain mixture, add the water of 2.2kg, soak 1 hour, be heated to boiling, decoct 3 hours, decoction liquor is filtered, filtering residue adds the water of 1.6kg again, be heated to boiling, decoct 3 hours, decoction liquor is filtered, the filtrate mixing of twice, concentrating under reduced pressure, remove part aqueous solvent, obtain the soup decoct 2 of 1g/ml crude drug concentration.

Soup decoct 3

By Rhizoma Drynariae 62g, Cortex Eucommiae 32g, Rhizoma Cibotii 42g, Caulis Spatholobi 32g, Myrrha 32g, Rhizoma Curcumae Longae 37g, Fructus Mume 12g, Radix Et Caulis Acanthopanacis Senticosi 32g, Herba Visci 42g, Herba Thesii Longifolii 22g, Radix Campanumoeae 27g, pittosporm root 27g, wind and cold grass 22g, Herba Tagetis Patulae 17g, Conyza japonica 22g, Radix Gentianae Macrophyllae 32g, Radix Morindae Officinalis 32g, Semen Cuscutae 27g, Ramulus Cinnamomi 27g and Herba Centipedae 17g shreds respectively, the product of chopping mixes, obtain mixture, add the water of 2.2kg, soak 1 hour, be heated to boiling, decoct 3 hours, decoction liquor is filtered, filtering residue adds the water of 1.6kg again, be heated to boiling, decoct 3 hours, decoction liquor is filtered, the filtrate mixing of twice, concentrating under reduced pressure, remove part aqueous solvent, obtain the soup decoct 3 of 1g/ml crude drug concentration.

Tablet 1

By Rhizoma Drynariae 600g, Cortex Eucommiae 300g, Rhizoma Cibotii 400g, Caulis Spatholobi 300g, Myrrha 300g, Rhizoma Curcumae Longae 350g, Fructus Mume 100g, Radix Et Caulis Acanthopanacis Senticosi 300g, Herba Visci 400g, Herba Thesii Longifolii 200g, Radix Campanumoeae 250g, pittosporm root 250g, wind and cold grass 200g, Herba Tagetis Patulae 150g, Conyza japonica 200g, Radix Gentianae Macrophyllae 300g, Radix Morindae Officinalis 300g, Semen Cuscutae 250g, Ramulus Cinnamomi 250g and Herba Centipedae 150g shreds respectively, the product of chopping mixes, obtain mixture, add the water of 22kg, soak 1 hour, be heated to boiling, decoct 3 hours, decoction liquor is filtered, filtering residue adds the water of 16kg again, be heated to boiling, decoct 3 hours, decoction liquor is filtered, the filtrate mixing of twice, concentrating under reduced pressure, remove aqueous solvent, obtain and get dry extract, be ground into powder, cross 100 mesh sieves, acquisition is sieved fine powder, get 2kg fine powder, add starch 500g and microcrystalline Cellulose 700g, mixing, granulate, add Magnesium Stearate proper quantity, mixing, be pressed into 1000, film coating, obtain.

Clinical data

Physical data

170 examples are between year July in May, 2011 to 2013 and go to a doctor in I Out-patient Department patient, are divided into two groups at random, treatment group 85 example, wherein man 49 example, female 36 example; Minimum 22 years old of age, maximum 69 years old, average (40.30 ± 5.23) year; The course of disease is the shortest 10 days, the longest 5 years, average (1.06 ± 0.19) year; Matched group 85 example, wherein man 51 example, female 34 example; Minimum 20 years old of age, maximum 64 years old, average (41.27 ± 4.96) year; The course of disease is the shortest 7 days, the longest 3 years; On average (0.93 ± 0.11) year.All cases is all made a definite diagnosis through CT examination, and gets rid of the diseases such as Lumber Vertebra Tumors, tuberculosis, diabetes.Two groups of physical data, through statistical procedures difference no statistical significance (P>0.05), have clinical comparability.

Therapeutic Method

The soup decoct 1 that treatment group adopts the embodiment of the present invention 1 for oral administration to prepare, every day 2 doses, every agent 150ml, 7d are a course for the treatment of, treat for 2 each courses for the treatment of altogether, adopt acupuncture treatment simultaneously, be specially acupoint selection: bilateral shen shu; In Ipsilateral Huantiao, Chengfu, committee, chengshan, Xuanzhong.Operation: patient gets ventricumbent position, 75% ethanol routine disinfection.Shen shu adopts 1.5 cun of No. 30 acupuncture needles to spinal column direction diagonal stabbing 1.0-1.2 cun, and Huantiao adopts 3 cun of No. 30 acupuncture needles to stab 2.0-2.5 cun slightly downwards diagonally, and make local acid swollen, have numb inductance to radiate to lower limb, all the other each caves are with 1.5 cun of vertical inserting needle 1.0-1.2 of No. 30 acupuncture needles cun.Shen shu executes reinforcement, more than to spread manuer in holes catharsis, every pin each twisted 1min, 120r/min, have the sour sense of numbness and distention for degree so that patient is conscious, let the acupuncture needle remain at a certain point 30min, and every the 10min hand-manipulating of needle once, treating 1 every day, is for 7 times a course for the treatment of, continuously 2 courses for the treatment of of treatment.

Matched group adopts ibuprofen oral, each 0.6g, every day 3 times; Prednisone is oral, each 10mg, every day 3 times, taking medicine after meal, and 7d is a course for the treatment of.Start prednisone 2nd course for the treatment of to successively decrease every day 2.5mg, treat 2 courses for the treatment of altogether, adopt the acupuncture treatment method that embodiment 1 is identical simultaneously.

Statistical procedures

Adopt SPSS13.0 statistical software, enumeration data adopt chi-square criterion, measurement data with represent, adopt t inspection, with P < 0.05 for difference has statistical significance.

Curative effect determinate standard

According to " disease of tcm Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine promulgates.Cure: symptom and sign disappears completely, can recover original work taken up, follows up a case by regular visits to more than 1 year non-recidivist; Effective: clinical symptom disappearance, original work can be engaged in, follow up a case by regular visits to and do not recur half a year; Effective: pain relief, and meet inducement such as symptom after overwork, feel wind and cold or drug withdrawal and have recurrence; Invalid: clinical symptoms, sign are improved not obvious.

Result

Two groups of therapeutic outcomes, in table 1.

Table 1 liang group therapeutic outcome comparative example (%)

Group	n	Cure	Effectively	Invalid	Total effective rate (%)
						Treatment group	85	51(60.0)	31(36.5)	3(3.5)	100
Matched group	85	25(29.4)	41(48.2)	19(22.3)	66(77.6)

As can be seen from Table 1, adopt Chinese medicine Combined with Acupuncture provided by the invention to treat, better can treat sciatica.

Patient, female, 56 years old, works before 2 weeks after rain with descending, go home namely to feel chronic problem, do not give attention, playing i.e. sense right lumbar region pain the 2nd day morning can not stand up, pain outside on rear side of buttocks, thigh, after shank emits to foot, can not walk with descending, therefore carry out the court's diagnosis and treatment.Have a medical check-up: straight-leg raising test is positive, and Achilles tendon reflex weakens.Face dolorosa, companion's inappetence, vexed, light red tongue, white and thin fur, deep-slow pulse.Examine as sciatica.Soup decoct 1 prepared by treatment the present invention, daily 2 times, each 150ml.Coordinate in acupuncture Huantiao, shen shu, Chihpien, fengshi, committee, gb 34, after bringing about the desired sensation, let the acupuncture needle remain at a certain point 30min, every day 1 time.Within 2nd day, namely pain be clearly better, and can walk with descending, fully recover after 8d days.

Lee, man, 53 years old, first visit on July 25 in 2013.Patient's readme sciatica more than 3 years, tired or often recur after suffering from cold, feel exacerbation of symptoms because climate change is prominent one week before, right lower limb is from hip joint extremely sufficient radiated pain, and night, the pain increased, can not squat down, and walking disorder, once used western medicines in treatment, poor effect.Check: RG plough shape flesh tenderness is obvious, and straight-leg raising test is positive.Pale tongue with white fur, stringy and thready pulse.Western medicine diagnose is sciatica.Tcm diagnosis is arthromyodynia (arthralgia due to cold), by the soup decoct adopting embodiment 1 to prepare, and daily 2 times, each 150ml; Combined with Acupuncture bilateral shen shu, in Ipsilateral Huantiao, Chengfu, committee, chengshan, Xuanzhong, wherein shen shu executes reinforcement, more than to spread manuer in holes catharsis, every day 1 time, above treatment is equal was for 7 times 1 course for the treatment of, after 2 courses for the treatment of, patient's symptom and sign disappears completely, walking, activity freely, continue to strengthen 1 course for the treatment of of treatment by top, follow up a case by regular visits to thereafter and do not recur for 2 years again.

All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.

The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (7)

1. be used for the treatment of a Chinese medicine for sciatica, it is characterized in that: crude drug is made up of Rhizoma Drynariae, the Cortex Eucommiae, Rhizoma Cibotii, Caulis Spatholobi, Myrrha, Rhizoma Curcumae Longae, Fructus Mume, Radix Et Caulis Acanthopanacis Senticosi, Herba Visci, Herba Thesii Longifolii, Radix Campanumoeae, pittosporm root, wind and cold grass, Herba Tagetis Patulae, Conyza japonica, Radix Gentianae Macrophyllae, Radix Morindae Officinalis, Semen Cuscutae, Ramulus Cinnamomi and Herba Centipedae;

The weight portion of each raw material is respectively Rhizoma Drynariae 55 weight portion ~ 65 weight portion, the Cortex Eucommiae 25 weight portion ~ 35 weight portion, Rhizoma Cibotii 35 weight portion ~ 45 weight portion, Caulis Spatholobi 25 weight portion ~ 35 weight portion, Myrrha 25 weight portion ~ 35 weight portion, Rhizoma Curcumae Longae 30 weight portion ~ 40 weight portion, Fructus Mume 5 weight portion ~ 15 weight portion, Radix Et Caulis Acanthopanacis Senticosi 25 weight portion ~ 35 weight portion, Herba Visci 35 weight portion ~ 45 weight portion, Herba Thesii Longifolii 15 weight portion ~ 25 weight portion, Radix Campanumoeae 20 weight portion ~ 30 weight portion, pittosporm root 20 weight portion ~ 30 weight portion, wind and cold grass 15 weight portion ~ 25 weight portions, Herba Tagetis Patulae 10 weight portion ~ 20 weight portion, Conyza japonica 15 weight portion ~ 25 weight portion, Radix Gentianae Macrophyllae 25 weight portion ~ 35 weight portion, Radix Morindae Officinalis 25 weight portion ~ 35 weight portion, Semen Cuscutae 20 weight portion ~ 30 weight portion, Ramulus Cinnamomi 20 weight portion ~ 30 weight portion and Herba Centipedae 10 weight portion ~ 20 weight portion.

2. Chinese medicine as claimed in claim 1, it is characterized in that: the weight portion of each crude drug is respectively Rhizoma Drynariae 58 weight portion ~ 62 weight portion, the Cortex Eucommiae 28 weight portion ~ 32 weight portion, Rhizoma Cibotii 38 weight portion ~ 42 weight portion, Caulis Spatholobi 28 weight portion ~ 32 weight portion, Myrrha 28 weight portion ~ 32 weight portion, Rhizoma Curcumae Longae 33 weight portion ~ 37 weight portion, Fructus Mume 8 weight portion ~ 12 weight portion, Radix Et Caulis Acanthopanacis Senticosi 28 weight portion ~ 32 weight portion, Herba Visci 38 weight portion ~ 42 weight portion, Herba Thesii Longifolii 18 weight portion ~ 22 weight portion, Radix Campanumoeae 23 weight portion ~ 27 weight portion, pittosporm root 23 weight portion ~ 27 weight portion, wind and cold grass 18 weight portion ~ 22 weight portions, Herba Tagetis Patulae 13 weight portion ~ 17 weight portion, Conyza japonica 18 weight portion ~ 22 weight portion, Radix Gentianae Macrophyllae 28 weight portion ~ 32 weight portion, Radix Morindae Officinalis 28 weight portion ~ 32 weight portion, Semen Cuscutae 23 weight portion ~ 27 weight portion, Ramulus Cinnamomi 23 weight portion ~ 27 weight portion and Herba Centipedae 13 weight portion ~ 17 weight portion.

3. Chinese medicine as claimed in claim 1 or 2, it is characterized in that: the weight portion of each crude drug is respectively Rhizoma Drynariae 60 weight portion, the Cortex Eucommiae 30 weight portion, Rhizoma Cibotii 40 weight portion, Caulis Spatholobi 30 weight portion, Myrrha 30 weight portion, Rhizoma Curcumae Longae 35 weight portion, Fructus Mume 10 weight portion, Radix Et Caulis Acanthopanacis Senticosi 30 weight portion, Herba Visci 40 weight portion, Herba Thesii Longifolii 20 weight portion, Radix Campanumoeae 25 weight portion, pittosporm root 25 weight portion, wind and cold grass 20 weight portions, Herba Tagetis Patulae 15 weight portion, Conyza japonica 20 weight portion, Radix Gentianae Macrophyllae 30 weight portion, Radix Morindae Officinalis 30 weight portion, Semen Cuscutae 25 weight portion, Ramulus Cinnamomi 25 weight portion and Herba Centipedae 15 weight portion.

4. Chinese medicine as claimed in claim 1 or 2, is characterized in that: described extract oral uses.

5. Chinese medicine as claimed in claim 1 or 2, is characterized in that: described Chinese drug preparation becomes soup decoct and tablet.

6. the preparation method of Chinese medicine described in claim 1 or 2, is characterized in that: when this Chinese drug preparation becomes soup decoct, be specially,

Shredded respectively by each crude drug, the product of chopping mixes according to above-mentioned weight portion, obtains mixture, add the water relative to this mixture 3 ~ 5 times of quality, soak 1 hour, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, and filtering residue adds the water relative to mixture 2 ~ 4 times of quality again, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, the filtrate mixing of twice, concentrating under reduced pressure, removes part aqueous solvent, obtains the soup decoct of 1g/ml crude drug concentration.

7. the preparation method of Chinese medicine described in claim 1 or 2, is characterized in that: when this Chinese drug preparation becomes tablet, specifically comprise,

The first step, shredded respectively by each crude drug, the product of chopping mixes according to above-mentioned weight portion, obtains mixture, add the water relative to this mixture 3 ~ 5 times of quality, soak 1 hour, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, filtering residue adds the water relative to mixture 2 ~ 4 times of quality again, is heated to boiling, decocts 2 ~ 3 hours, decoction liquor is filtered, the filtrate mixing of twice, concentrating under reduced pressure, removes aqueous solvent, obtain and get dry extract, be ground into powder, cross 100 mesh sieves, obtain the fine powder that sieves;

Second step, gets 200g fine powder, adds starch 40-60g and microcrystalline Cellulose 60-80g, mixing, granulates, adds Magnesium Stearate proper quantity, and mixing, is pressed into 1000, film coating, obtains final product.