CN104547034A - Traditional Chinese medicinal preparation for treating hyperosteogeny and method for preparing preparation - Google Patents
Traditional Chinese medicinal preparation for treating hyperosteogeny and method for preparing preparation Download PDFInfo
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Abstract
The invention belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicinal preparation for treating hyperosteogeny and a method for preparing the preparation. The preparation is prepared from the following raw materials in parts by weight: 3-5 parts of atractylodes lancea, 20-30 parts of lumbricus, 20-30 parts of davallia mariesii, 10-15 parts of common clubmoss herbs, 5-10 parts of akebiaquinata, 20-30 parts of cibotium barometz, 20-30 parts of radix dipsaci, 15-20 parts of lithospermum erythrorhizon, 10-15 parts of carthamus tinctorius, 20-30 parts of semen strychni, 3-5 parts of scorpions, 5-10 parts of acanthopanacis cortex, 5-10 parts of panax notoginseng, 15-20 parts of bungarus parvus, 15-20 parts of boswellia carterii and 15-20 parts of myrrh. The traditional Chinese medicinal materials used by the invention conforms to pharmacopoeia regulations of the People's Republic of China and is safe and reliable; the combination of all the materials has the functions of dispelling wind, removing dampness, warming channel and expelling cold, promoting blood circulation to remove meridian obstruction, and regulating and nourishing liver and kidney; the preparation has the characteristics of being definite in curative effect, quick to take effect, high in cure rate without side effects and the like.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation for the treatment of hyperosteogeny and preparation method thereof.
Background technology
Hyperosteogeny is multiple degenerative diseases of aged, belong to the traditional Chinese medical science " rheumatism involving the bone " category, refer to that pushing away bone edge or joint margins, articular surface and apophysis place bone trabecula increases and increase with bone density, because its shape is sometimes as lip or as beak, therefore be called lip-like projection or bone Ao, also bony spur is, as rheumatic rheumatoid arthritis, cervical vertebra, lumbar vertebra, intervertebral disc, knee hyperplasia, the pertinacious diseases such as sciatica.Modern medicine is called Hypertrophic osteoarthritis, is a kind of commonly encountered diseases and the frequently-occurring disease of orthopaedics.It is generally acknowledged that the plus chronic damage of old tissue degeneratiaon is main pathogenic, primary disease onset is slow, and have joint aches in early days, action is dumb, and the pain increased afterwards, limitation of activity.The histological examination of bone Ao, is entirely normal structure without any pathological change, so be referred to as senile osteoarthritis, also known as osteoarthritis, osteoarthritis, proliferative arthritis.Hypertrophiarthritis and " rheumatism involving the bone " alleged by the traditional Chinese medical science are also referred to as " bony spur ", and " insensitive impediment " etc. are referred to as hyperosteogeny.
The traditional Chinese medical science thinks that bone matrix hyperplasia is relevant with wound, strain, obstruction of collaterals by blood stasis, the damp that is affected by the cold, phlegm resistance, caused by liver and kidney deficiency etc.Hyperosteogeny be apt to occur in 35-70 year age bracket, be engaged in teacher, accounting, heavy worker and athlete's sickness rate high, the common feature of these people is that motion and work are many, joint wear weight, makes joint produce degeneration bone and becomes.Lesion degree and age size rigidity of the body weak in close relations, knee joint degeneration, the thinning rear secondary hyperosteogeny of articular cartilage wearing and tearing, this disease generally shows as arthralgia, ache more severe when particularly above going downstairs, can not squat down, belong to aseptic inflammation, have an injection eat antibiotic medicine have no idea eliminate aseptic inflammation.
Shape is as the change of beak sample on X-ray film for hyperosteogeny, and people are called it " bony spur ", this title comparison image.With advancing age, the cartilage in joint is degenerated gradually, and the elasticity of cell reduces, osteoarthrosis is being worn unconsciously, neck, waist, knee joint, heel that especially activity is large, and the articular cartilage of damage is not when having blood vessel to supply nutrition, just be difficult to repair, at this moment more vigorous in the peripheral blood recycle ratio of articular cartilage, just there will be compensatory cartilage and increase, this is the predecessor of hyperosteogeny, of long duration, the cartilage of hypertrophy is again by calcification, and hyperosteogeny that Here it is, is also bony spur.Clinical research proves, the factors such as the generation of hyperosteogeny increased with the age, sex, occupation, racial inheritance factor, body constitution, posture is bad and the bone angular vein stasis of blood is stagnant, bone inner high voltage are relevant.Hyperostosis constitutional estranged and Secondary cases two kinds.
This disease is chronic disease, and disease time is long, difficulty is effected a radical cure, easily recurred, and plain stubborn, patient is very painful.Such disease is a kind of persistent ailment, perhaps the good results are evident at that time to beat hormone drug, but it is very large to the harm of health, and have certain dependency, western medical treatment effect is not very desirable, is exactly nothing but open surgery when taking medicine and not having effect, but operates on and just the bony spur on surface is excised, bony spur also president, cannot effect a radical cure after a time.
Summary of the invention
According to above the deficiencies in the prior art, the invention provides a kind of Chinese medicine preparation for the treatment of hyperosteogeny and preparation method thereof, it is evident in efficacy, safe and reliable, have no side effect, there is wide potential applicability in clinical practice.
A kind of Chinese medicine preparation for the treatment of hyperosteogeny of the present invention, according to weight parts, formed by following preparation of raw material: Rhizoma Atractylodis 3 ~ 5 parts, Pheretima 20 ~ 30 parts, Rhizoma Drynariae 20 ~ 30 parts, Herba Lycopodii 10 ~ 15 parts, Caulis Akebiae 5 ~ 10 parts, Rhizoma Cibotii 20 ~ 30 parts, Radix Dipsaci 20 ~ 30 parts, Radix Arnebiae (Radix Lithospermi) 15 ~ 20 parts, 10 ~ 15 parts, Flos Carthami, Semen Strychni 20 ~ 30 parts, Scorpio 3 ~ 5 parts, Cortex Acanthopancis 5 ~ 10 parts, Radix Notoginseng 5 ~ 10 parts, Agkistrodon 15 ~ 20 parts, Olibanum 15 ~ 20 parts and Myrrha 15 ~ 20 parts.
Wherein, preferred version is as follows:
According to weight parts, formed by following preparation of raw material: Rhizoma Atractylodis 3 parts, Pheretima 20 parts, Rhizoma Drynariae 20 parts, Herba Lycopodii 10 parts, Caulis Akebiae 5 parts, Rhizoma Cibotii 20 parts, Radix Dipsaci 20 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, 10 parts, Flos Carthami, Semen Strychni 20 parts, Scorpio 3 parts, Cortex Acanthopancis 5 parts, Radix Notoginseng 5 parts, Agkistrodon 15 parts, Olibanum 15 parts and Myrrha 15 parts.
Or following formula: according to weight parts, is formed by following preparation of raw material: Rhizoma Atractylodis 5 parts, Pheretima 30 parts, Rhizoma Drynariae 30 parts, Herba Lycopodii 15 parts, Caulis Akebiae 10 parts, Rhizoma Cibotii 30 parts, Radix Dipsaci 30 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, 15 parts, Flos Carthami, Semen Strychni 30 parts, Scorpio 5 parts, Cortex Acanthopancis 10 parts, Radix Notoginseng 10 parts, Agkistrodon 20 parts, Olibanum 20 parts and Myrrha 20 parts.
The preparation method of the Chinese medicine preparation for the treatment of hyperosteogeny of the present invention, prepare in accordance with the following methods: take raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10 ~ 20 minutes, add water again and do not have powder 3 ~ 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 ~ 30 minutes to boiling, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
When taking, each 300ml, one day twice.
Pharmacology analysis:
Rhizoma Atractylodis: acrid in the mouth, hardship, warm in nature; Return spleen, stomach warp.Cure mainly the spleen and stomach being stranded by dampness, gastral cavity painful abdominal mass abdominal distention, vomiting and nausea is had loose bowels, leukorrhagia stranguria with turbid discharge, pestilence, communicable subtropical diseases, malaria, and cholera is rheumatism exogenous, cold-damp damp arthralgia, beriberi, flaccidity, nyctalopia.
Pheretima: cure mainly calentura mania and irritation, infantile convulsion, cough with asthma, headache conjunctival congestion, laryngopharynx swelling and pain, urinary obstruction, Fengshi Guanjie pain, hemiplegia.
Rhizoma Drynariae: bitter in the mouth, temperature, nontoxic.Enter liver, kidney channel.The kidney invigorating bone strengthening, continues and hinders pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.
Herba Lycopodii: toil temperature, enters Liver Channel.Expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral.For anemofrigid-damp arthralgia, muscle arteries and veins contracture pain carbuncle.External is controlled osteopatia sprain and is swollen and ache.
Caulis Akebiae: cold nature, bitter in the mouth.There is pathogenic fire purging row water, the function of promoting blood circulation.For hot urination, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, sore throat pharyngalgia, inflexible pain all over, women's amenorrhea, galactostasis.
Rhizoma Cibotii: bitter, sweet, temperature.Return liver, kidney channel.Wind-damp dispelling, invigorating the liver and kidney, strong waist knee joint.Cure mainly rheumatic arthralgia, soreness of the waist and knees, weakness of the lower extremities, frequent micturition, the enuresis, leukorrhagia.External application incised wound is stopped blooding.
Radix Dipsaci: invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating.Control aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer swells.
Radix Arnebiae (Radix Lithospermi): nature and flavor are sweet, salty, cold.GUIXIN, Liver Channel.Removing heat from blood, invigorates blood circulation, removing toxic substances rash.Contain for heat in blood poison, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.Cure mainly warm macule, jaundice due to damp-heat, purpura, tell, be defeated in battle, hematuria, stranguria with turbid discharge, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.
Flos Carthami: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contributes to controlling amenorrhea, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, the twinge of the breast side of body, traumatic injury, skin infection swells and ache curative effect.Have blood circulation promoting and blood stasis dispelling, wet dissipation goes the effect swollen.
Semen Strychni: by dispelling the wind and dampness pathogens insensitive impediment or contracture numbness.With controlling wound pain caused by ecchymoma and ulcer sore pain.Cancerous protuberance is planted by Zhiduo County, has certain curative effect.Treatment poliomyelitis sequela, prolapse of lumbar intervertebral disc, trigeminal neuralgia, rheumatoid arthritis, traumatic injury, pain due to blood stasis, anemofrigid-damp arthralgia, general joint contracture, numbness, cancerous protuberance etc.Cure mainly throat arthralgia pain, swollen ulcer drug, migratory arthralgia pain, fracture, facial paralysis, myasthenia gravis.
Scorpio: be used for that treatment infantile convulsion, rheumatism, hemiplegia, facial hemiparalysis, deaf language are puckery, spasm of hands and feet etc.Scorpion venom has dispeling the wind, detoxifies, pain relieving, dredging collateral effect, have certain curative effect to esophageal carcinoma, hepatocarcinoma, colon cancer etc.
Cortex Acanthopancis: dispelling the wind and dampness pathogens flaccidity syndrome and arthralgia syndrome, strengthening bone and muscle, eliminating phlegm and removing dampness, supports kidney benefit essence, removes emaciation due to emotional upset water, and reason beriberi lumbago, controls all poison of skin ulcer scabies.Can break by aversion to wind blood, extremity are unsuccessful, and harmful wind is hurted sb.'s feelings, weak foot, and waist, and master for many years blood stasis at musculus cutaneus, controls numbness wet interior not enough, main empty win.
Radix Notoginseng: cure mainly hemostasis, dissipating blood stasis, detumescence, analgesic therapy.Control haematemesis, hemoptysis, epistaxis, have blood in stool, dysentery, metrorrhagia, lump in the abdomen, puerperal blood faints, retention of lochia, fall and flutter blood stasis, traumatic hemorrhage, carbuncle pain.
Agkistrodon: dispel the wind, dredging collateral, relieving convulsion.For rheumatoid arthritis stubborn, numbness contracture, middle air port is askew, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Olibanum: regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Myrrha: cure mainly breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, lump in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain.There is the effect such as promoting blood circulation and stopping pain, detumescence and promoting granulation.
The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.All medicine phases and have effect of expelling wind and removing dampness, dispelling cold by warming the meridian, promoting blood circulation to remove obstruction in the collateral, adjusting and reinforcing liver and kidney, treatment hyperosteogeny has that determined curative effect, instant effect, cure rate are high, the feature such as have no side effect.
Outcome measure:
1, case selection: as the Chinese medicine preparation for the treatment of hyperosteogeny, selects hyperosteogeny patient 100 clinical observation of making a definite diagnosis, wherein male 52 example, women 48 example, 45 ~ 85 years old age, 58 years old mean age, the shortest person of the course of disease 3 months, most elder 9 years, average 2 years.
2, Therapeutic Method:
Take Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 300ml, seven days 1 courses for the treatment of.
3, diagnostic criteria:
" the disease of tcm diagnostic criteria " of the diagnostic criteria reference State Administration of Traditional Chinese Medicine promulgation of lumbar hyperosteogency: take the photograph sheet inspection through x-ray or CT lumbar vertebra and be diagnosed as lumbar vertebra hyperosteogeny; All patients all has chronic back pain medical history; Some patients is with the symptom such as numbness of lower limbs or pain.
4, efficacy evaluation: (1) healing: X-ray or CT check contrast bony spur and disappear, the extensive recovery operation of energy, energy is movable or walk more than 2 kilometers without pain symptom.(2) take a turn for the better: arthralgia alleviates, and movable function obviously improves.(3) do not heal: symptom, sign are without improvement.
5, therapeutic effect: cure 80 examples, take a turn for the better 14, do not heal 6 examples, and effective percentage is 94%, and inefficiency is 6%.
Below enumerate a model case:
Go into business certain, man, and 50 years old, people from Qingdao, once suffered from lumbago, hospital x-ray prompting: lumbar vertebra hyperosteogeny, connects injection, his quick, Daphne giraldii Nitsche injection of Ghana, weigh time light during its state of an illness through traction, acupuncture, massage acupoint injection therapy snow.Fail to cure.Look into: waist is stiff, numb limbs and tense tendons, limitation of activity, musculus sacrospinalis two takes up the obvious tenderness of 4-5 lumbar vertebra, and right side waist 5 vertebra has radioactivity tenderness.The two numbness of lower limbs of companion, difficulty in walking, dizziness and blurred vision, blurred vision, insomnia forgetfulness.Take Chinese medicine decoction of the present invention, after the course for the treatment of, pain obviously alleviates, and can manage household affairs, and fully recovers after three courses for the treatment of.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1:
A kind of Chinese medicine preparation for the treatment of hyperosteogeny, according to weight parts, formed by following preparation of raw material: Rhizoma Atractylodis 3 parts, Pheretima 20 parts, Rhizoma Drynariae 20 parts, Herba Lycopodii 10 parts, Caulis Akebiae 5 parts, Rhizoma Cibotii 20 parts, Radix Dipsaci 20 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, 10 parts, Flos Carthami, Semen Strychni 20 parts, Scorpio 3 parts, Cortex Acanthopancis 5 parts, Radix Notoginseng 5 parts, Agkistrodon 15 parts, Olibanum 15 parts and Myrrha 15 parts.
Embodiment 2:
A kind of Chinese medicine preparation for the treatment of hyperosteogeny, according to weight parts, formed by following preparation of raw material: Rhizoma Atractylodis 5 parts, Pheretima 30 parts, Rhizoma Drynariae 30 parts, Herba Lycopodii 15 parts, Caulis Akebiae 10 parts, Rhizoma Cibotii 30 parts, Radix Dipsaci 30 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, 15 parts, Flos Carthami, Semen Strychni 30 parts, Scorpio 5 parts, Cortex Acanthopancis 10 parts, Radix Notoginseng 10 parts, Agkistrodon 20 parts, Olibanum 20 parts and Myrrha 20 parts.
Embodiment 3:
Embodiment 1 is according to the Chinese medicine preparation of following step preparation treatment hyperosteogeny, take raw material of Chinese medicine according to formula and join in container, adding water covers powder and soaks 10 minutes, then adds water and do not have powder 3 centimetres, decoct with high heat and use slow fire boiling again instead 20 minutes to boiling, get filtrate; And then add water and do not have powder 3 centimetres, decoct with high heat and uses slow fire boiling again instead 15 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
Embodiment 4:
Embodiment 2 is according to the Chinese medicine preparation of following step preparation treatment hyperosteogeny, take raw material of Chinese medicine according to formula and join in container, adding water covers powder and soaks 20 minutes, then adds water and do not have powder 5 centimetres, decoct with high heat and use slow fire boiling again instead 30 minutes to boiling, get filtrate; And then add water and do not have powder 5 centimetres, decoct with high heat and uses slow fire boiling again instead 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
Claims (4)
1. treat the Chinese medicine preparation of hyperosteogeny for one kind, it is characterized in that according to weight parts, formed by following preparation of raw material: Rhizoma Atractylodis 3 ~ 5 parts, Pheretima 20 ~ 30 parts, Rhizoma Drynariae 20 ~ 30 parts, Herba Lycopodii 10 ~ 15 parts, Caulis Akebiae 5 ~ 10 parts, Rhizoma Cibotii 20 ~ 30 parts, Radix Dipsaci 20 ~ 30 parts, Radix Arnebiae (Radix Lithospermi) 15 ~ 20 parts, 10 ~ 15 parts, Flos Carthami, Semen Strychni 20 ~ 30 parts, Scorpio 3 ~ 5 parts, Cortex Acanthopancis 5 ~ 10 parts, Radix Notoginseng 5 ~ 10 parts, Agkistrodon 15 ~ 20 parts, Olibanum 15 ~ 20 parts and Myrrha 15 ~ 20 parts.
2. a kind of Chinese medicine preparation for the treatment of hyperosteogeny according to claim 1, it is characterized in that according to weight parts, formed by following preparation of raw material: Rhizoma Atractylodis 3 parts, Pheretima 20 parts, Rhizoma Drynariae 20 parts, Herba Lycopodii 10 parts, Caulis Akebiae 5 parts, Rhizoma Cibotii 20 parts, Radix Dipsaci 20 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, 10 parts, Flos Carthami, Semen Strychni 20 parts, Scorpio 3 parts, Cortex Acanthopancis 5 parts, Radix Notoginseng 5 parts, Agkistrodon 15 parts, Olibanum 15 parts and Myrrha 15 parts.
3. a kind of Chinese medicine preparation for the treatment of hyperosteogeny according to claim 1, it is characterized in that according to weight parts, formed by following preparation of raw material: Rhizoma Atractylodis 5 parts, Pheretima 30 parts, Rhizoma Drynariae 30 parts, Herba Lycopodii 15 parts, Caulis Akebiae 10 parts, Rhizoma Cibotii 30 parts, Radix Dipsaci 30 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, 15 parts, Flos Carthami, Semen Strychni 30 parts, Scorpio 5 parts, Cortex Acanthopancis 10 parts, Radix Notoginseng 10 parts, Agkistrodon 20 parts, Olibanum 20 parts and Myrrha 20 parts.
4. the preparation method of the Chinese medicine preparation of a treatment hyperosteogeny according to claim 1, it is characterized in that preparing in accordance with the following methods: take raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10 ~ 20 minutes, add water again and do not have powder 3 ~ 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 ~ 30 minutes to boiling, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267465A (en) * | 2015-10-09 | 2016-01-27 | 马浩广 | Traditional Chinese medicine preparation for treating hyperostosis |
| CN106215079A (en) * | 2016-07-18 | 2016-12-14 | 王恩禄 | A kind of Chinese medicine composition treating hyperosteogeny |
| CN106334070A (en) * | 2016-09-20 | 2017-01-18 | 陈亚平 | Anti-osteoproliferation traditional Chinese medicine |
-
2014
- 2014-12-30 CN CN201410844522.XA patent/CN104547034A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267465A (en) * | 2015-10-09 | 2016-01-27 | 马浩广 | Traditional Chinese medicine preparation for treating hyperostosis |
| CN106215079A (en) * | 2016-07-18 | 2016-12-14 | 王恩禄 | A kind of Chinese medicine composition treating hyperosteogeny |
| CN106334070A (en) * | 2016-09-20 | 2017-01-18 | 陈亚平 | Anti-osteoproliferation traditional Chinese medicine |
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