CN102784328A - Medicament for treating ankylosing spondylitis and preparation method of medicament - Google Patents

Medicament for treating ankylosing spondylitis and preparation method of medicament Download PDF

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CN102784328A
CN102784328A CN201210304942XA CN201210304942A CN102784328A CN 102784328 A CN102784328 A CN 102784328A CN 201210304942X A CN201210304942X A CN 201210304942XA CN 201210304942 A CN201210304942 A CN 201210304942A CN 102784328 A CN102784328 A CN 102784328A
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radix
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ankylosing spondylitis
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medicament
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CN102784328B (en
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孙超
史桂芳
潘光辉
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Abstract

The invention relates to a traditional Chinese medicine and a preparation method thereof, in particular to a medicament for treating ankylosing spondylitis and a preparation method of the medicament. The medicament for treating ankylosing spondylitis comprises teasel roots, east asian tree fern rhizome, epimedium, eucommia, processed aconite, cassia twig, drynaria, raw rehmannia roots, red paeony roots, coix seeds, common clubmoss herb, white muscardine silkworm, notopterygium and heracleum, divaricate saposhnikovia roots and achyranthes bidentata. The preparation method includes: proportionally mixing the ingredients, soaking the mixture in cold water for 1 hour, boiling with strong fire prior to decocting with soft fire for 20 minutes, pouring out the liquid medicine, then adding water over the traditional Chinese medicine, decocting to boil prior to decocting with soft fire for 15 minutes, and uniformly mixing the two liquid medicines. Usage of the medicament includes: drinking twice a day by oral administration and taking twenty times for a treatment course during administration. The preparation method has the advantages of capability of treating both the symptoms and the root causes, high safety, little side effect, reliable curative effect and acceptability to patients.

Description

Medicine of treatment ankylosing spondylitis and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine medicine and preparation method thereof, especially a kind of medicine of treating ankylosing spondylitis and preparation method thereof.
Background technology
Ankylosing spondylitis belongs to categories such as Chinese medicine " numbness ", " rheumatism involving the bone ", " BI-syndrome involved the kidney ", " governor vessel is sick ", is a kind of aggressive inflammation, and morbidity is slow, and the state of an illness is grown and risen and fallen, and often involves bones of the body bone joint.The traditional Chinese medical science thinks that its pathogenesis is a kidney yang deficiency, and the governor vessel stasis of blood stagnates.Control suitable warming the kidney to activate YANG, superintend and direct collateral dredging by force.Pathogeny it be unclear that at present, but generally believes that with heredity, wound, inhabitation humidity and intestinal infection height correlation is arranged.The medicine universality of existing treatment ankylosing spondylitis is poor, often specific crowd is had certain curative effect, to other crowd DeGrain even invalid fully then.
Summary of the invention
The purpose of this invention is to provide a kind of treating both the principal and secondary aspects of a disease, medicine of the treatment ankylosing spondylitis that good effect, side effect are little and preparation method thereof.
The medicine of treatment ankylosing spondylitis according to the invention is characterized in that comprising following compositions in portion by weight: Radix Dipsaci 10-15, Rhizoma Cibotii 15-20, Herba Epimedii 6-10, Cortex Eucommiae 10-15, Radix Aconiti Lateralis Preparata 6-10, Ramulus Cinnamomi 6-10, Rhizoma Drynariae 10-20, living each 15-20 of Radix Rehmanniae Preparata, each 15-20 of the red Radix Paeoniae Alba, Semen Coicis 20-30, Herba Lycopodii 10-15, Bombyx Batryticatus 9-12, each 10-15 of Qiang's Radix Angelicae Pubescentis, windproof 6-10, Radix Achyranthis Bidentatae 12-18.
As further improvement of the present invention, the medicine of described treatment ankylosing spondylitis comprises following compositions in portion by weight: Radix Dipsaci 10, Rhizoma Cibotii 15, Herba Epimedii 6, the Cortex Eucommiae 10, Radix Aconiti Lateralis Preparata 6, Ramulus Cinnamomi 6, Rhizoma Drynariae 10, give birth to Radix Rehmanniae Preparata each 15, the red Radix Paeoniae Alba each 15, Semen Coicis 20, Herba Lycopodii 10, Bombyx Batryticatus 9, Qiang's Radix Angelicae Pubescentis each 10, windproof 6, Radix Achyranthis Bidentatae 12.
As further improvement of the present invention, the medicine of described treatment ankylosing spondylitis comprises following compositions in portion by weight: Radix Dipsaci 12, Rhizoma Cibotii 16, Herba Epimedii 8, the Cortex Eucommiae 12, Radix Aconiti Lateralis Preparata 8, Ramulus Cinnamomi 8, Rhizoma Drynariae 15, give birth to Radix Rehmanniae Preparata each 18, the red Radix Paeoniae Alba each 18, Semen Coicis 25, Herba Lycopodii 12, Bombyx Batryticatus 10, Qiang's Radix Angelicae Pubescentis each 12, windproof 8, Radix Achyranthis Bidentatae 15.
As further improvement of the present invention, the medicine of described treatment ankylosing spondylitis comprises following compositions in portion by weight: Radix Dipsaci 15, Rhizoma Cibotii 20, Herba Epimedii 10, the Cortex Eucommiae 15, Radix Aconiti Lateralis Preparata 10, Ramulus Cinnamomi 10, Rhizoma Drynariae 20, give birth to Radix Rehmanniae Preparata each 20, the red Radix Paeoniae Alba each 20, Semen Coicis 30, Herba Lycopodii 15, Bombyx Batryticatus 12, Qiang's Radix Angelicae Pubescentis each 15, windproof 10, Radix Achyranthis Bidentatae 18.
The method for preparing of the medicine of aforesaid treatment ankylosing spondylitis is characterized in that comprising the steps:
A) preparation of a medicinal liquid; Be immersed in 1000-1500 part cold water after said each composition mixed, soak at room temperature 1 hour, the boiled pot of intense fire back was with 20 minutes at a simmer then; Stop heating; Liquid is wherein separated with solid constituent, separate the liquid component that obtains and be medicinal liquid one time, solid constituent is medicinal residues;
B) cold water is prepared in the preparation of secondary medicinal liquid, and the weight of cold water is equal in weight with a medicinal liquid of separating; These cold water are added in the above-mentioned medicinal residues; Fry in shallow oil 15 minutes at a simmer of the back of boiling behind the boiled pot of intense fire, stop heating, wherein liquid is separated with solid constituent; Separate the liquid component that obtains and be the secondary medicinal liquid, solid constituent is the secondary medicinal residues;
C) medicine preparation is medicinal liquid and secondary medicinal liquid equal proportion mix homogeneously the medicine of said treatment ankylosing spondylitis.
Radix Dipsaci: have another name called Radix Dipsaci, be the root of herbaceos perennial Radix Dipsaci, because of ability " synthetism of continuous folding " is gained the name.Have invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, the continuous effect of hindering, ending metrorrhagia of rolling over.Be used for aching pain in waist and back, podomere flaccidity syndrome and arthralgia syndrome, fall pounce on wound, decrease muscle folding bone, red, metrorrhagia is leaked in fetal movement, seminal emission, leukorrhagia, carbuncle skin ulcer are swollen.
Rhizoma Cibotii: the dry rhizome that is concha Anodonta seu Cristaria section plant Rhizoma Cibotii.Belong to strong muscles and bones medicine, the unstrong disease of muscles and bones is had the dual function of treatment and health care.The large-scale autochthonal fern of Cibotium barometz (L.) J. Sm. is born in the dark and damp place of foot of the hill limes marginis and sylvan life, the acid ground.Autumn, two seasons of winter excavate, and remove silt, drying; Or remove hard root, petiole and golden yellow fine hair, and cut sheet, drying is " giving birth to the Rhizoma Cibotii sheet "; Decocting in water or steam after, shine to 6 seventy percent and do, cut sheet, drying is " ripe Rhizoma Cibotii sheet ".Function is invigorating the liver and kidney, strong spinal column, wind-damp dispelling.
Herba Epimedii: be the dried leaves of Berberidaceae plant Herba Epimedii, arrow leaf Herba Epimedii, pubescence Herba Epimedii or Herba Epimedii.Tapped when summer, autumn, stem and leaf was luxuriant, remove stem, slightly stalk and impurity, dry or dry in the shade.Chinese medicine is thought Herba Epimedii property acrid-sweet flavor, temperature, and the effect of kidney invigorating and YANG supporting, expelling wind and removing dampness is arranged.The Herba Epimedii stem and leaf contains icariine and volatile oil.Verified, Herba Epimedii has the effect of androgen appearance, and its effect is better than Gecko and Hippocampus.Simultaneously, Herba Epimedii can also suppress vasomotor center, and the expansion peripheral vessels makes blood pressure drops, and can antitussive, eliminate the phlegm, relieving asthma, poliovirus, Staphylococcus albus, staphylococcus aureus etc. are also had significant inhibitory effect.
The Cortex Eucommiae: be the dry bark of the Eucommiaceae plant Cortex Eucommiae.Tool invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering, many effects such as antiabortive.In recent years, both at home and abroad the expert has carried out careful repeatedly research to Cortex Eucommiae composition, and Cortex Eucommiae free amino acid is few, a small amount of protein that contains, be with most foodstuffs like adequate proteins, promptly can hydrolysis detect 8 seed amino acids to needed by human.Measure 15 kinds of contained mineral elements of the Cortex Eucommiae, trace element such as zinc, copper, ferrum have wherein been arranged, reached macroelements such as calcium, phosphorus, potassium, magnesium.The Cortex Eucommiae has invigorating the liver and kidney, and rubbish in the body is removed in bone and muscle strengthening, strengthens the human body cell substance metabolism; Prevent that muscle skeleton is aging, the balance human blood-pressure, the decomposer inner cholesterol reduces body fat; Recover blood vessel elasticity, diuresis heat clearing away, broad-spectrum antiseptic; Stimulating central nervous system improves white blood cell count, remarkable efficacy such as enhancing human immune.
Radix Aconiti Lateralis Preparata: be the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx..Excavate the first tenday period of a month in the last ten-days period in June to August, removes parent root, fibrous root and silt, practise to claim " mud Radix Aconiti Lateralis Preparata ", through salting, water float, boil, method such as stir-fry concocts the back and reduces toxicity, title " Radix Aconiti Lateralis Preparata ".Radix Aconiti Lateralis Preparata has recuperating depleted YANG and rescuing the patient from collapse, and it is supporing yang to mend fire, by the effect of wind-cold damp pathogen.Cure mainly the YANG-depletion collapse, the cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, arthralgia due to cold-dampnes etc.
Ramulus Cinnamomi: be the cinnamomic dry twig of Lauraceae aiphyllium plant.Spring, summer are cut twig, dry or dry in the shade, and thinly slice or segment is used.Control exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.Main benefitting liver and lung gas, headache, migratory arthralgia joint spasm and pain.Ramulus Cinnamomi Xin Ganwen is prosperous, and major function is a promoting the flow of QI-blood by warming the meridian, can lead to yang-energy and induces sweat, a little less than the effect of diaphoresis is comparatively slow.So control wind and cold table disease, wind and cold is lossless, and normal and Herba Ephedrae compatibility is to strengthen the effect of its diaphoresis; Control wind and cold table disease, spontaneous perspiration aversion to wind then without Herba Ephedrae, cold expelling is defended, delivered to the same usefulness of polygamy Radix Paeoniae to coordinate battalion.Rhizoma Drynariae: another name monkey Rhizoma Zingiberis Recens, hair Rhizoma Zingiberis Recens, drynaria baronii, the pteridophyta Mongolian oak Herba pteridii latiusculi rhizome of growing nonparasitically upon another plant for Polypodiaceae is perennial.The tradition traditional Chinese medical science is usually used in kidney invigorating and YANG supporting, promoting blood circulation and hemostasis, synthetism is continuous hinders.Modern study thinks that Rhizoma Drynariae has the effect of enhancing immunity, increase hemocyte.
Giving birth to Radix Rehmanniae Preparata is the title that closes of the Radix Rehmanniae and Radix Rehmanniae Preparata.
The Radix Rehmanniae also is Radix Rehmanniae, the fresh or exsiccant tuber of Scrophulariaceae herbaceos perennial Radix Rehmanniae.Excavate autumn, removes removing LU, fibrous root, is the bright Radix Rehmanniae; Root baking is molten to be done to eighty per cant, and inner blackening, pinches into bulk, is Radix Rehmanniae.Sweet-bitter flavor, cold in nature and go into blood system, clearing away heat and cooling blood.Cure mainly fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon is hindered constipation.Radix Rehmanniae Preparata also is Radix Rehmanniae Preparata, and for Radix Rehmanniae is mixed steaming to inside and outside darkish complexion, glossy through adding yellow wine, or directly steaming forms to deceiving profit.Cutting sheet uses.Radix Rehmanniae Preparata has the YIN nourishing of enriching blood effect, and traditional traditional Chinese medical science is usually used in blood deficiency and yellow complexion, and is dizzy, palpitation and insomnia, and menoxenia, diseases such as metrorrhagia also can be used for hectic fever hectic fever due to YIN-deficiency, the night sweat of deficiency of kidney yin, disease such as pass out semen, quench one's thirst.
The red Radix Paeoniae Alba is the title that closes of the Radix Paeoniae Rubra and the Radix Paeoniae Alba.The Radix Paeoniae Rubra and the Radix Paeoniae Alba are the dry root of ranunculaceae plant Radix Paeoniae.Radix Paeoniae opens red colored person, is Radix Paeoniae Rubra.Open the person of spending in vain, be the Radix Paeoniae Alba.
Radix Paeoniae Rubra: abnormal smells from the patient is bitter flat, nontoxic.Cure mainly pathogen stomachache, remove arthralgia due to stagnation of blood, broken hard long-pending, cold and heat, sick tired, pain relieving, diuresis, QI invigorating.
The Radix Paeoniae Alba: picric acid, cold.Be usually used in nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Semen Coicis: have another name called Semen Coicis, Semen Coicis, Semen Coicis, native corn, Semen Coicis, a reality, heart of a lotus seed pearl, careless pearl pearl, jobstears, Semen Coicis, NLIUGU.It is the dry mature kernal of grass Semen Coicis.Main component is protein, vitamin B1, B2, and it can promote the metabolism of body inner blood and moisture, and diuresis, anthydropic effect are arranged, and is also regarded the articles for use of going on a diet.Be usually used in weakness of the spleen and stomach again, loose stool diarrhoea, or vaginal discharge diseases of women, the insufficiency of the spleen leading to overabundance of dampness edema, dysuria, or beriberi swells and ache; Damp and hot arthralgia pain, contracture of the limbs, miserable pain; Lung abscess cough and spit purulent sputum, or enterodynia contracture stomachache.
Herba Lycopodii: the another name Radix et Rhizoma Smilacis Ripariae, big stretch muscle, water along muscle rattan, Radix Schisandrae Micranthae, the Radix Stemonae and shake bamboo, Herba Poae Sphondylodis, oxtail and stretch muscle, oxtail joint, oxtail volume, water polo flower, Da Ye and stretch muscle, whiteback greenbrier rhizome, stretch the muscle spirit.Herb for Lycopodiaceae Lycopodium plant Lycopodium clavatum.Herba Lycopodii contains sterols such as terpenoid, cupreol such as alkaloids such as lycopodine, excellent lycoclavanin alkali, Lycopodium clavatum triol, Lycopodium clavatum tetrol ketone, reaches compositions such as vanillic acid, ferulic acid.Have cooling, hypotensive activity.Be used for expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral.This product Xinsan, bitter dry, warm through, to expel rheumatism, hepatic especially good flow of qi.Control anemofrigid-damp arthralgia, joint aches, joint stuffiness, can with compatibilities such as Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Ramulus Cinnamomi, the Radix Paeoniae Alba; If limbs are weak, numbness of the skin should be equal to usefulness with Lignum Pini Nodi, Herba Aristolochiae Mollissimae, Radix Clematidis.
Bombyx Batryticatus: be the ossified dry Scorpio of larva infection muscardine of Bombycidae insecticide Bombycis mori.Cylindrical, many bendings and shrinkage.Be about 2~5 centimetres, 4~7 millimeters of diameters.How surface canescence or existing light brown are by the adularescent Refined Mercurous chloride.Effect with expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Be usually used in controlling apoplectic aphasia, infantile convulsion, wind syndrome of head, acute throat trouble.
Qiang's Radix Angelicae Pubescentis is the title that closes of Rhizoma Et Radix Notopterygii and Radix Angelicae Pubescentis.
Rhizoma Et Radix Notopterygii: the dry rhizome and the root that are samphire Rhizoma Et Radix Notopterygii or Radix et Rhizoma Notopterygii.Effect with diffusing exterior cold, wind-damp dispelling, sharp joint.Wind and cold, lossless, the anemofrigid-damp arthralgia of headache, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore are usually used in curing cold.Also can be used for impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffer from a deficiency of the kidney and do to breathe heavily, have loose bowels just before dawn.Its up merit of dispersing is stronger, kind controls head and upper limb joint is painful.
Radix Angelicae Pubescentis:Dry root for the heavy peristome Radix Angelicae Sinensis of samphire.Its acrid in the mouth, hardship, tepor.Has expelling wind and dampness; The effect of dispersing cold for relieving pain.Be used for anemofrigid-damp arthralgia, lumbocrural pain, few cloudy volt wind headache, headache toothache.
Windproof: as to have another name called: SHANQINCAI, Herba Stenosolenii saxatilis, copper rue, Hui Yun, return grass, Rhizoma Cibotii, hundred fragrant-flowered garlic, hundred kinds, screen, RADIX SAPOSHINOKOVIAE from Northeast, Radix Ligustici Brachylobi, rasix seseli.It is the windproof root of Umbelliferae herbaceos perennial.Its acrid in the mouth, sweet, slightly warm in nature.Has the effect that expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion are jerked surely.Be usually used in diseases such as headache due to common cold, rubella pruritus, rheumatic arthralgia, tetanus opisthotonus, gnathospasma, tic spasm.
Radix Achyranthis Bidentatae: forThe dry root of amaranthaceous plant Radix Achyranthis Bidentatae.Be dispel the wind medicine and blood circulation and stasis-eliminating medicine commonly used.Its bitter in the mouth; Acid; Property is put down.Cure mainly soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhea, puerperal abdominal pain due to blood stasis, note of the ancient Chinese abdominal mass, retention of placenta, pyretic stranguria, stranguria with blood, traumatic injury, carbuncle malignant boil, laryngopharynx swelling and pain etc.
The medicine of this treatment ankylosing spondylitis organically combines above-mentioned various compositions, gives full play to the pharmacological action of various compositions, and played the kidney invigorating and superintended and directed by force, the logical analgesic effect that stagnates of blood stasis dispelling, the method treating both the principal and secondary aspects of a disease, safely, effectively, side effect is little.Selected for 100 example ages in the test of 12-70 year patient clinical comparison, course of treatment of medication, produce effects is 65 examples, effectively is 35 examples; After medication two courses of treatment, produce effects is 85 examples, effectively is 15 examples.
The specific embodiment
Embodiment 1:
The medicine of treatment ankylosing spondylitis according to the invention comprises following compositions in portion by weight: Radix Dipsaci 10, Rhizoma Cibotii 15, Herba Epimedii 6, the Cortex Eucommiae 10, Radix Aconiti Lateralis Preparata 6, Ramulus Cinnamomi 6, Rhizoma Drynariae 10, give birth to Radix Rehmanniae Preparata each 15, the red Radix Paeoniae Alba each 15, Semen Coicis 20, Herba Lycopodii 10, Bombyx Batryticatus 9, Qiang's Radix Angelicae Pubescentis each 10, windproof 6, Radix Achyranthis Bidentatae 12.
Its preparation method following steps:
A) preparation of a medicinal liquid; Be immersed in 1000-1500 part cold water after said each composition mixed, soak at room temperature 1 hour, the boiled pot of intense fire back was with 20 minutes at a simmer then; Stop heating; Liquid is wherein separated with solid constituent, separate the liquid component that obtains and be medicinal liquid one time, solid constituent is medicinal residues;
B) cold water is prepared in the preparation of secondary medicinal liquid, and the weight of cold water is equal in weight with a medicinal liquid of separating; These cold water are added in the above-mentioned medicinal residues; Fry in shallow oil 15 minutes at a simmer of the back of boiling behind the boiled pot of intense fire, stop heating, wherein liquid is separated with solid constituent; Separate the liquid component that obtains and be the secondary medicinal liquid, solid constituent is the secondary medicinal residues;
C) medicine preparation is medicinal liquid and secondary medicinal liquid equal proportion mix homogeneously the medicine of said treatment ankylosing spondylitis.
Every day twice when taking, each oral 500-1000 grams of drinking, 20 times is a course of treatment.
Patient Lee, the man, 24 years old, the waist and sacrum pain of showing effect repeatedly 6 months was not alleviated after the rest, alleviated after the activity, stood up difficulty night, waist anterior flexion and rear stretching function limitation, having a medical check-up refers to distance 15cm, and the pillow wall is apart from 3cm, and the pelvis separating experiment is positive, and HLA-B27 is positive.Give the present embodiment Drug therapy, every day twice, each oral 500-1000 grams of drinking, 20 times is a course of treatment.Treat 1 aftersensation waist and sacrum pain and obviously alleviate, the readme whole body has kind of a relaxation.After treating a course of treatment, patient's readme has not had tangible sticky feeling, follows up a case by regular visits to not outbreak in 1 year.
Implement case 2:
With embodiment 1, as follows with the adjustment of the parts by weight of each composition: Radix Dipsaci 12, Rhizoma Cibotii 16, Herba Epimedii 8, the Cortex Eucommiae 12, Radix Aconiti Lateralis Preparata 8, Ramulus Cinnamomi 8, Rhizoma Drynariae 15, give birth to Radix Rehmanniae Preparata each 18, the red Radix Paeoniae Alba each 18, Semen Coicis 25, Herba Lycopodii 12, Bombyx Batryticatus 10, Qiang's Radix Angelicae Pubescentis respectively 12, windproof 8, Radix Achyranthis Bidentatae 15.
Patient Chen, the man, 28 years old, the waist and sacrum pain of showing effect repeatedly 3 years, companion's morning stiff sense half a year, fear of cold is serious, soreness of the waist and knees, overcast and rainy increasing the weight of stands up difficulty night, it is poor to sleep, receive can, the time abdominal distention arranged, loose stool greatly, pale tongue with white fur, slow pulse.Be diagnosed as AS in the provincial hospital before 2 years, medicine such as oral sulfasalazine once, heterodyne.Give the present embodiment Drug therapy, every day twice, each oral 500-1000 grams of drinking, 20 times is a course of treatment.After treating a course of treatment, it is very comfortable that patient's readme entire back warms up, and conscious abdominal part is also loose much; First quarter moon is followed up a case by regular visits to after treating 2 courses of treatment, patient's readme, and lumbosacral region does not have pain again; Overcast and rainy sensation is a bit sent out plate, has not been afraid of cold, and the place ahead of continuing is treated 2 times to consolidate curative effect; Readme did not just have so comfortable mistake in these several years, followed up a case by regular visits to not recurrence in a year.
Implement case 3:
With embodiment 1, the parts by weight of each composition are adjusted as follows:
Radix Dipsaci 15, Rhizoma Cibotii 20, Herba Epimedii 10, the Cortex Eucommiae 15, Radix Aconiti Lateralis Preparata 10, Ramulus Cinnamomi 10, Rhizoma Drynariae 20, give birth to Radix Rehmanniae Preparata each 20, the red Radix Paeoniae Alba each 20, Semen Coicis 30, Herba Lycopodii 15, Bombyx Batryticatus 12, Qiang's Radix Angelicae Pubescentis each 15, windproof 10, Radix Achyranthis Bidentatae 18.
Patient Zheng, man 38 years old made a definite diagnosis ankylosing spondylitis 8 years, once oral sulfasalazine, diclofenac that, Thalidomide etc.; Effect is general, existing patient's waist is anteflexion, after stretch and the lateral bending function all limited, cervical vertebra leans forward, function limitation; With tangible feeling of fatigue, it is poor to sleep, poor appetite, soreness of the waist and knees; Fear of cold, cold is sent out in trick, and the iritis history was arranged.Give the present embodiment Drug therapy, every day twice, each oral 500-1000 grams of drinking, 20 times is a course of treatment.After the course of treatment, patient's readme oneself is just as having changed a people, and energy, muscle power all improve significantly, and not too have been afraid of cold, and trick is not cool, and waist and neck are flexible, continues to treat 1 course of treatment to consolidate curative effect.Follow up a case by regular visits to not recurrence in a year.

Claims (5)

1. the medicine of treatment ankylosing spondylitis is characterized in that comprising following compositions in portion by weight: Radix Dipsaci 10-15, Rhizoma Cibotii 15-20, Herba Epimedii 6-10, Cortex Eucommiae 10-15, Radix Aconiti Lateralis Preparata 6-10, Ramulus Cinnamomi 6-10, Rhizoma Drynariae 10-20, living each 15-20 of Radix Rehmanniae Preparata, each 15-20 of the red Radix Paeoniae Alba, Semen Coicis 20-30, Herba Lycopodii 10-15, Bombyx Batryticatus 9-12, each 10-15 of Qiang's Radix Angelicae Pubescentis, windproof 6-10, Radix Achyranthis Bidentatae 12-18.
2. the medicine of treatment ankylosing spondylitis according to claim 1 is characterized in that comprising following compositions in portion by weight: Radix Dipsaci 10, Rhizoma Cibotii 15, Herba Epimedii 6, the Cortex Eucommiae 10, Radix Aconiti Lateralis Preparata 6, Ramulus Cinnamomi 6, Rhizoma Drynariae 10, give birth to Radix Rehmanniae Preparata each 15, the red Radix Paeoniae Alba each 15, Semen Coicis 20, Herba Lycopodii 10, Bombyx Batryticatus 9, Qiang's Radix Angelicae Pubescentis each 10, windproof 6, Radix Achyranthis Bidentatae 12.
3. the medicine of treatment ankylosing spondylitis according to claim 1 is characterized in that comprising following compositions in portion by weight: Radix Dipsaci 12, Rhizoma Cibotii 16, Herba Epimedii 8, the Cortex Eucommiae 12, Radix Aconiti Lateralis Preparata 8, Ramulus Cinnamomi 8, Rhizoma Drynariae 15, give birth to Radix Rehmanniae Preparata each 18, the red Radix Paeoniae Alba each 18, Semen Coicis 25, Herba Lycopodii 12, Bombyx Batryticatus 10, Qiang's Radix Angelicae Pubescentis each 12, windproof 8, Radix Achyranthis Bidentatae 15.
4. the medicine of treatment ankylosing spondylitis according to claim 1 is characterized in that comprising following compositions in portion by weight: Radix Dipsaci 15, Rhizoma Cibotii 20, Herba Epimedii 10, the Cortex Eucommiae 15, Radix Aconiti Lateralis Preparata 10, Ramulus Cinnamomi 10, Rhizoma Drynariae 20, give birth to Radix Rehmanniae Preparata each 20, the red Radix Paeoniae Alba each 20, Semen Coicis 30, Herba Lycopodii 15, Bombyx Batryticatus 12, Qiang's Radix Angelicae Pubescentis each 15, windproof 10, Radix Achyranthis Bidentatae 18.
5. like the method for preparing of the medicine of the described treatment ankylosing spondylitis of claim 1-4, it is characterized in that comprising the steps:
A) preparation of a medicinal liquid; Be immersed in 1000-1500 part cold water after said each composition mixed, soak at room temperature 1 hour, the boiled pot of intense fire back was with 20 minutes at a simmer then; Stop heating; Liquid is wherein separated with solid constituent, separate the liquid component that obtains and be medicinal liquid one time, solid constituent is medicinal residues;
B) cold water is prepared in the preparation of secondary medicinal liquid, and the weight of cold water is equal in weight with a medicinal liquid of separating; These cold water are added in the above-mentioned medicinal residues; Fry in shallow oil 15 minutes at a simmer of the back of boiling behind the boiled pot of intense fire, stop heating, wherein liquid is separated with solid constituent; Separate the liquid component that obtains and be the secondary medicinal liquid, solid constituent is the secondary medicinal residues;
C) medicine preparation is medicinal liquid and secondary medicinal liquid equal proportion mix homogeneously the medicine of said treatment ankylosing spondylitis.
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CN103028066A (en) * 2012-12-20 2013-04-10 周瑾 Traditional Chinese medicine composition for treating ankylosing spondylitis
CN104042736A (en) * 2014-06-21 2014-09-17 徐显廷 Traditional Chinese medicine oral liquid for treatment of ankylosing spondylitis
CN105582043A (en) * 2015-12-30 2016-05-18 中国中医科学院中医临床基础医学研究所 Traditional Chinese medicine composition for treating ankylosing spondylitis
CN105833124A (en) * 2016-04-01 2016-08-10 李海生 Medicine for treating ankylosing spondylitis

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CN103028066A (en) * 2012-12-20 2013-04-10 周瑾 Traditional Chinese medicine composition for treating ankylosing spondylitis
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