CN105641256A

CN105641256A - Chinese herbal medicine composition for treating chalazion of children

Info

Publication number: CN105641256A
Application number: CN201610182434.7A
Authority: CN
Inventors: 杜凯; 徐文玲
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-03-28
Filing date: 2016-03-28
Publication date: 2016-06-08

Abstract

The invention relates to the field of Chinese herbal medicine, and discloses Chinese herbal medicine composition for treating chalazion of children. The chalazion (known as Meibomian cyst) is one of ophthalmic diseases, mostly teenagers, especially children are repeatedly infected, and patients and family feel painful and worry. Materials are selected according to etiology and pathogenesis and Chinese herbal medicine's pharmacological effect, and Chinese herbal medicine composition has the advantages of scientific formula, symptomatic treatment, cause and symptom treatment effect, outstanding treatment effect, and the like. The Chinese herbal medicine composition can be used for oral administration and external use, drug property can reach focus directly under double action, and effect is outstanding. Through clinical experiment, overall response rate is up to 94.19%, so that the Chinese herbal medicine composition is worthy of clinical population.

Description

A kind of Chinese medicine composition treating child's chalazion

Technical field

The present invention relates to the field of Chinese medicines, specifically a kind of Chinese medicine composition treating child's chalazion.

Background technology

Chalazion (is commonly called as chalazion) and is the common disease of ophthalmology, is more common in teenager, especially child, normal recurrent exerbation, causes suffering to patient and family members and worried. Western medicine thinks that chalazion is owing to the discharge line of tarsal glands blocks, a kind of chronic inflammation granuloma that glandular tube endocrine retention is formed in tarsus. Upper lower eyelid all can occur, can single-shot or multiple. Clinical manifestation mainly has eyelid subcutaneous without tenderness scleroma, can promote. After treatment in time, many no pains, do not affect one's power of vision, have spontaneous recovery to be inclined to, prognosis bona.

The traditional Chinese medical science claims this sick for chalazion, and the traditional Chinese medical science is thought, this is sick sends out in upper palpebra inferior, its position be five take turns in meat wheel, planted agent's taste, therefore the not normal person of spleen and stomach function often suffers from. The such as breast feeding of child's spleen and stomach functional defect is improper, or eating and drinking without temperance, or the pungent scattered cold sweet greasy product of surfeit, causes transporting and transforming function of the spleen and stomach not normal, damp-heat accumulation, and wet retention of phlegm is raw, hinders in meridians, causes QI and blood being obstructed, and superior born of the same parents' eyelid then easily occurs.

Western medical treatment primary disease mainly has the methods such as thermotherapy, Local eye drop liquid medicine, naturopathy, intracapsular injection hormone, operation. Generally use the symptomatic treatments such as Antibiotic Eye Ointment, the method for nonresponder's then multiplex operation. For operative treatment, child is difficult to mate to, also the recurrent exerbation having or at a glance recurrence or eyes volley, for operation less than.

Summary of the invention

For existing current treatment status, it is an object of the invention to provide a kind of Chinese medicine composition treating child's chalazion, there is the advantage such as taking convenience, determined curative effect.

The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition treating child's chalazion, is made up of the crude drug of following weight parts proportioning: Radix urenae procumbentis 20-30, flower root 20-30, Fructus Akebiae 10-20, Radix Musae 15-30, Rhoeo spathacea 30-50, phlegm-fire grass 30-60, Caulis Trachelospermi 30-50, Radix Rhois chinensis 60-100.

Preferably, a kind of Chinese medicine composition treating child's chalazion, it is made up of the crude drug of following weight parts proportioning: Radix urenae procumbentis 25, flower root 25, Fructus Akebiae 15, Radix Musae 20, Rhoeo spathacea 40, phlegm-fire grass 60, Caulis Trachelospermi 40, Radix Rhois chinensis 80.

Contained by Chinese medicine composition of the present invention, the pharmacological property of each crude drug is as follows.

Radix urenae procumbentis: for the root of Malvaceae plant Herba urenae procumbentis. Nature and flavor: sweetness and bitterness, temperature. Enter spleen, stomach, the heart, kidney four warp. Can spleen invigorating drying, blood stasis dispelling is invigorated blood circulation. Cure mainly wind alunite arthritis, impairment caused by overstrain flaccidity of the lower limbs, edema, malaria, dysmenorrhea, leucorrhea, traumatic injury. swollen ulcer drug. " Quanzhou book on Chinese herbal medicine " is recorded: " blood stasis removing is invigorated blood circulation for expelling wind and removing dampness, channels sootheing and network vessel quickening, warming the stomach spleen invigorating. Control ailment said due to cold or exposure muscles and bones contracture, influenza lung-heat, swollen ulcer drug. ", " Jiangxi traditional herbal medicine proved recipe " is recorded: " spleen invigorating, dries, and reduces phlegm. ".

Hua Gen: for the root of Hamamelidaceae Plants flower. Slightly warm in nature, bitter and puckery flavor. Enter liver, stomach, large intestine, kidney four warp. Can stop blooding, invigorate blood circulation, restrain astringent or styptic treatment for spontaneous sweating. Curing mainly hemoptysis, stomachache is had loose bowels, proctoptosis, and podomere is ached, leucorrhea, and lochia is not smooth, and traumatic injury is spitted blood, toothache. " east, Fujian book on Chinese herbal medicine ": " invigorating the spleen for eliminating dampness, dredge the meridian passage. Controlling joint wind pain, extremity are aching and limp, and stomachache is had loose bowels ". Modern pharmacological research finds, in isolated perfusion is tested, the decoct of flower root can expand rat hindlimb blood vessel the edema that antihistaminic is caused; This effect is likely to be caused by tannin contained therein. For the broken blood vessels of Canis familiaris L. outside the mixture of leaf, there is anastalsis.

Fructus Akebiae: for BENTONG section plant Caulis Akebiae, threeleaf akebia, white BENTONG dry mature fruit. Nature and flavor: sweet, cold. Return liver,spleen,kidney warp. Can liver-smoothing, qi-regulating, invigorate blood circulation, eliminating stasis to stop pain, relieving restlessness diuresis. Curing mainly stomachache due to hyperactive liver-QI attacking the stomach, gastric heat food is slow-witted, excessive thirst, also Hakuri, lumbago, hypochondriac pain, hernia, menopause, and uterus drops.

Radix Musae: for the rhizome of Musaceae plant Musa basjoo Sieb. Et Zucc.. Nature and flavor: sweet in the mouth; Cold in nature. Return stomach, spleen, Liver Channel. Can heat-clearing and toxic substances removing; Quench the thirst; Diuresis. Cure mainly calentura; Unhappiness is quenched one's thirst; Carbuncle furunculosis; Erysipelas; Metrorrhagia; Stranguria with turbid discharge; Edema; Beriberi. " Bencao Congxin " is recorded: " removing toxic substances of purging heat. Controlling all toxic swellings, carbuncle on the back is intended to extremely, wandering erysipelas rash, headache due to pathogenic wind-heat, and puerperal, blood was swollen, and drinking-water of quenching one's thirst, sky row is fanatical, blood strangury and dry pain, ulcerous nonunion. ".

Rhoeo spathacea: have another name called Zi Jinlan, purple, Rhizoma Bletillae, red general, Herba Chenopodii Hybridi, freshwater mussel flower, concha Anodonta seu Cristaria flower, be the evergreen persistent root herbs of one of Commelianaceae Rhoeo spathacea genus, be used as medicine with dried floral. Nature and flavor: sweet, light are cool. Can removing heat-phlegm, eliminating pathogenic heat from blood to cure dysentery. It is mainly used in xeropulmonary cough, spitting of blood, pertussis, tuberculous lymphadenitis, dysentery, have blood in stool.

Phlegm-fire grass: for the herb of Commelianaceae plant Murdannia bracteata (C. B. Clarke) O. UhtzeexJ. K. Mortoh. Nature and flavor: sweet; Light; Cool. Can dissipating phlegm and resolving masses; Clearing heat and freeing strangury. Cure mainly scrofula sucutaneous nodule; Pyretic stranguria.

Caulis Trachelospermi: for the dry rattan of band leaf of apocynaceae plant trachelospermum jasminoide. Cold nature, bitter in the mouth. GUIXIN, liver, kidney channel. There is expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, clearing away heat and cooling blood, effect of removing toxic substances and promoting subsidence of swelling. For beriberoid pyretic arthralgia, muscle arteries and veins contracture, soreness of waist and knee joint, sore throat, carbuncle, injury from falling down.

Radix Rhois chinensis: for the tree root of Anacardiaceae plant Fructus rhois chinensis, can adopt when four, have dispel the wind, removing dampness, detumescence, the effect such as softening the hard mass. Nature and flavor: acid is salty, cool. Enter spleen, kidney two warp. Curing mainly cold, fever, cough, diarrhoea, edema, rheumatism numbness cancer, traumatic injury wound is swollen, and acute mastitis, tinea skin ulcer, disappear alcoholism. " south of the Five Ridges gather medicinal herbs record " is recorded: " Sweeling-eliminating medicine powder poison. Decoct the washing rotten head infections of teenager, can be antipruritic; Controlling acute mastitis, leg cramp disease, traumatic injury wound swells and ache, all pan-fried washings; With infusing drugs in wine, pain relieving, blood stasis removing, tissue regeneration promoting.", " east, Fujian book on Chinese herbal medicine " is recorded: " invigorating the spleen for eliminating dampness, strong muscle the kidney invigorating. Dispelling the wind and dampness pathogens arthralgia pain, extremity are aching and limp, abdominal distention lumbago, cough due to fluid-retention, edema, metrorrhagia. ", Guangzhou army " conventional Chinese herbal medicine handbook ": " removing heat from blood pathogenic fire reducing, eliminating blood stasis to promote regeneration of blood, control measles, cold, fever, band blood of coughing; Injury and bone fracture. ".

Present invention also offers the method for preparation and use of a kind of Chinese medicine composition treating child's chalazion: by the crude drug decocting three times of weight, add 5-8 times of water every time, front twice gained water decoction mixing, point early, evening be administered orally for 2 times, each 150ml; Third time gained water decoction heats to 30-40 degree Celsius, in the soak of sufferer place after soaking with towel, and every day three times, each 30 minutes.

The present invention chooses carefully each crude drug according to primary disease etiology and pathogenesis and the herbal pharmacology property of medicine, has the advantages such as scientific formulation, with strong points, treating both the principal and secondary aspects of a disease, therapeutic effect are prominent. The traditional Chinese medical science thinks that eyelid belongs to taste, spleen and stomach phase the exterior and the interior in internal organs, and The spleen has the function to transport and transform nutrients, and stomach department receives and is subject to, dysfunction of the spleen in transportation, and vital essence is condensed, and knot forms chalazion (chalazion). In Chinese medicine composition of the present invention, Radix urenae procumbentis returns spleen, stomach warp, can spleen invigorating warming the stomach, expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, flower root return stomach warp, can invigorate blood circulation, restrain astringent or styptic treatment for spontaneous sweating, expansion blood vessel, above two taste medicines coordinate jointly can effectively regulate taste; Fructus Akebiae returns spleen channel, can vital energy regualting and blood circulation-promoting, diuresis relieving restlessness, Radix Musae can quench the thirst in heat-clearing and toxic substances removing, diuresis, and this two taste is medicinal to rush down retention of heat in the spleen and stomach; Rhoeo spathacea, phlegm-fire grass can dissipating phlegm and resolving masses, clearing away heat and cooling blood, Caulis Trachelospermi coordinates the effect that can play expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, clearing away heat and cooling blood, detumescence softening the hard mass with Radix Rhois chinensis.

The present invention treats having the beneficial effects that of child's chalazion, and one is that this side gets final product function of spleen and stomach regulating, rushes down retention of heat in the spleen and stomach, again can expelling wind and removing dampness, removing heat from blood dredging collateral, dissipating phlegm and resolving masses, treat this sick treating both the principal and secondary aspects of a disease; Two is oral administration and externally used, medicine arrives focus by dual function, remarkably productive, the present invention utilizes the steam soak eye of Chinese herbs decoction, dual function by medicine and heating power soak, the skin at stimulation position, blood vessel, to raise eyelid temperature, so as to higher than the fusing point of tarsal glands lipid, be beneficial to the flowing of lipid, it is possible to so that eyelid, conjunctiva telangiectasis, local blood and lymph circulation is made to improve, it is beneficial to the optimum of tarsal glands or normal secretions, makes tarsal glands opening clear, promote drug osmotic, absorption and propagation; Three is that the present invention treats child's chalazion, has easy and simple to handle, safety and is suitable for the feature such as child's absorption without side reaction, drug dose, the child non-invasive being in growth and development stage is hindered, does not affect the living and studying of patient, and patient is prone to acceptance.

Detailed description of the invention

Embodiment 1: a kind of Chinese medicine composition treating child's chalazion: Radix urenae procumbentis 20 grams, flower root 20 grams, Fructus Akebiae 10 grams, Radix Musae 15 grams, Rhoeo spathacea 30 grams, phlegm-fire grass 30 grams, Caulis Trachelospermi 30 grams, Radix Rhois chinensis 60 grams.

Method of preparation and use: 1, by the oral medicine routine decocting of weight, first time adds 7 times of water, and second time adds 5 times of water, twice gained water decoction mixing, and point morning, evening are administered orally for 2 times, each 150ml; 2, third time adds 8 times of water, and gained water decoction heats to 33 degrees Celsius, in the soak of sufferer place after soaking with towel, and every day three times, each 30 minutes.

Embodiment 2: a kind of Chinese medicine composition treating child's chalazion: Radix urenae procumbentis 25 grams, flower root 25 grams, Fructus Akebiae 15 grams, Radix Musae 20 grams, Rhoeo spathacea 40 grams, phlegm-fire grass 60 grams, Caulis Trachelospermi 40 grams, Radix Rhois chinensis 80 grams.

Method of preparation and use: 1, by the oral medicine routine decocting of weight, first time adds 7 times of water, and second time adds 6 times of water, twice gained water decoction mixing, and point morning, evening are administered orally for 2 times, each 150ml; 2, third time adds 8 times of water, and gained water decoction heats to 35 degrees Celsius, in the soak of sufferer place after soaking with towel, and every day three times, each 30 minutes.

Embodiment 3: a kind of Chinese medicine composition treating child's chalazion: Radix urenae procumbentis 30 grams, flower root 30 grams, Fructus Akebiae 20 grams, Radix Musae 30 grams, Rhoeo spathacea 50 grams, phlegm-fire grass 60 grams, Caulis Trachelospermi 50 grams, Radix Rhois chinensis 100 grams.

Method of preparation and use: 1, by the oral medicine routine decocting of weight, first time adds 6 times of water, and second time adds 5 times of water, twice gained water decoction mixing, and point morning, evening are administered orally for 2 times, each 150ml; 2, third time adds 7 times of water, and gained water decoction heats to 37 degrees Celsius, in the soak of sufferer place after soaking with towel, and every day three times, each 30 minutes.

Analysis of clinical

1. clinical data

1.1 physical data:

Select the 166 example chalazion patients that 20l4 in August, 2008 front three in March general hospital institute is medical, male 90 example, women 76 example; Age 4-12 year, 8.6 years old mean age; Pathological changes diameter 4-10mm, average 6.8mm; The course of disease is 3 days 2 months, average 12 days. Be divided into observation group 86 example and matched group 80 example, these two groups of patients in the basic datas such as sex, age, the course of disease, disease compare, not statistically significant, there is comparability.

1.2 inclusive criterias:

Eyelid is subcutaneous touches scleroma, differs in size, and cyst is fixed on tarsus, smooth surface, cutaneous protuberance, and corresponding section palpebral conjunctiva is aubergine, not with skin adhesion, and light tenderness or without tenderness.

1.3 Therapeutic Method:

1.3.1 matched group

Entered subcutaneous and injection into cyst premix 5% triamcinolone acetonide 0.1ml+ dexamethasone 0.1ml by diseased region skin or conjunctival surface, use disinfecting cotton swab pressing injection site 3 minutes, advise patient's hot compress every day 2 times, each 5 minutes, further consultation after often spending 5 days, cyst diameter is more than 5mm, then row injection.

1.3.2 observation group

Take Chinese medicine composition of the present invention, prescription: Radix urenae procumbentis 25 grams, flower root 25 grams, Fructus Akebiae 15 grams, Radix Musae 20 grams, Rhoeo spathacea 40 grams, phlegm-fire grass 60 grams, Caulis Trachelospermi 40 grams, Radix Rhois chinensis 80 grams. Method of preparation and use is with above-described embodiment 2.

Compare two groups of patients curative effect situation after 5 days, 10 days, 15 days.

2. result

2.1 criterions of therapeutical effect:

Being evaluated according to chalazion dissipation situation, criterion of therapeutical effect is determined with reference to State Administration of Traditional Chinese Medicine's l994 version " diagnosis of common disease and curative effect judging standard ". Cyst is dissipated as healing; Cyst is reduced into improvement; Cyst size is invalid without change or recurrent exerbation.

2.2 therapeutic outcomes (see following table)

3. interpretation of result

3.1 statistical analysis

Adopting SPSS19.0 statistical software to carry out statistical analysis, enumeration data compares employing x2 inspection, and P < 0.05 is that difference is statistically significant.

3.2 data analysiss

Data according to table 1 show, the total effective rate of observation group is 94.19%, the effective percentage of matched group is 80%, illustrate to adopt traditional Chinese medicine composition for treating of the present invention observation group cure the matched group that effective percentage is substantially better than the injection of drug of employing, clinic is promoted.

Model case:

1, Zhang, man, 8 years old, occurred before 10 days that left eyelid is red and swollen, shed tears, secretions is more. Local hospital diagnosis is chalazion, gives Gernebcin eye drops, erythromycin eye ointment etc. and carries out locally treating having no obvious curative effects. Check: normal visual acuity, slightly red in left eyelid, touch by there being Semen phaseoli radiati size to harden, dry lip is thirsty, and two is just normal, and moderate pulse, red tongue tongue is white. Diagnosis is chalazion. Fang Yong: Radix urenae procumbentis 20 grams, flower root 20 grams, Fructus Akebiae 10 grams, Radix Musae 15 grams, Rhoeo spathacea 30 grams, phlegm-fire grass 30 grams, Caulis Trachelospermi 30 grams, Radix Rhois chinensis 60 grams. Red and swollen disappearance after 5 days, scleroma is obviously reduced. After following the service 5 days, scleroma disappears, and recovery from illness is followed up a case by regular visits to and do not recurred half a year.

2, often certain, female, 12 years old. Patient's ULLE occurs, more than a long karyomorphism scleroma moon, opening order unfavorable. Element eating savoury, invalid through antibiotic medicine and hot compress etc. for oral administration, diagnosis and treatment then. Through looking into: form is fat, left upper eyelid is subcutaneous touches 2mm*3mm scleroma, clear border, and without tenderness, conjunctiva is without hyperemia, red tongue, and greasy fur is Huang slightly, slippery and rapid pulse. Diagnosis: chalazion. Fang Yong: Radix urenae procumbentis 30 grams, flower root 30 grams, Fructus Akebiae 20 grams, Radix Musae 30 grams, Rhoeo spathacea 50 grams, phlegm-fire grass 60 grams, Caulis Trachelospermi 50 grams, Radix Rhois chinensis 100 grams. Red and swollen disappearance after 5 days, scleroma is obviously reduced. After following the service 5 days, scleroma disappears, and recovery from illness is followed up a case by regular visits to and do not recurred half a year.

3, Cao, man, 6 years old. Patient's ULLE occurs that grain of rice size is lumpd, it is found that more than first quarter moon, because nothing is uncomfortable, therefore does not control. Recently sensation eye is uncomfortable, and time rubs one's eyes, and nictation is on the point of. Looking into eye: normal visual acuity, left eye upper eyelid is subcutaneous touches 2 circular kernel shapes scleromas of differing in size, pressure not bitterly, with skin adhesion, the greater is about 5mm*6mm, corresponding position cutaneous protuberance, and in eyelid, corresponding position bulbar conjunctiva is aubergine. Convenient to both tasteless very. Pale tongue, thin fur thickness is greasy, rolling pulse. Diagnosis: chalazion. Fang Yong: Radix urenae procumbentis 20 grams, flower root 20 grams, Fructus Akebiae 10 grams, Radix Musae 15 grams, Rhoeo spathacea 30 grams, phlegm-fire grass 30 grams, Caulis Trachelospermi 30 grams, Radix Rhois chinensis 60 grams. After taking continuously 7, scleroma disappears, and recovery from illness is followed up a case by regular visits to 1 year and do not recurred.

4, Wang, female, 7 years old, Dual-eyelid had more than the scleroma moon, has foreign body sensation before three days. Checking: have a sorghum grain size lump in the middle part of right upper lid, that touches is harder, protrudes from conjunctival surface, conjunctival congestion, and bump pad is heavier; Upper left lower eyelid is respectively arranged with a lump. That touches is tougher, conjunctival congestion. Diagnosis: chalazion. Fang Yong: Radix urenae procumbentis 30 grams, flower root 30 grams, Fructus Akebiae 20 grams, Radix Musae 30 grams, Rhoeo spathacea 50 grams, phlegm-fire grass 60 grams, Caulis Trachelospermi 50 grams, Radix Rhois chinensis 100 grams. Congested disappearance after 5 days, scleroma is obviously reduced. After following the service 10 days, scleroma disappears, and recovery from illness is followed up a case by regular visits to 1 year and do not recurred.

Claims

1. the Chinese medicine composition treating child's chalazion, it is characterized in that, be made up of the crude drug of following weight: Radix urenae procumbentis 20-30, flower root 20-30, Fructus Akebiae 10-20, Radix Musae 15-30, Rhoeo spathacea 30-50, phlegm-fire grass 30-60, Caulis Trachelospermi 30-50, Radix Rhois chinensis 60-100.

2. a kind of Chinese medicine composition treating child's chalazion as claimed in claim 1, it is characterized in that, be made up of the crude drug of following weight: Radix urenae procumbentis 25, flower root 25, Fructus Akebiae 15, Radix Musae 20, Rhoeo spathacea 40, phlegm-fire grass 60, Caulis Trachelospermi 40, Radix Rhois chinensis 80.