CN102872420A - Medicine for treating rheumatic arthritis and preparation method thereof - Google Patents
Medicine for treating rheumatic arthritis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicine for treating rheumatic arthritis, and a preparation method thereof, belonging to the field of traditional Chinese medicine. The active ingredients of medicine comprise the raw materials in parts by weight: 12-18 parts of tinospora sinensis merr, 12-18 parts of lanatechead saussurea herb with flower, 15-30 parts of himalayan teasel root, 10-20 parts of pawpaws, 15-30 parts of FlemingiaphilippinensisMerr.etRolfe, 10-20 parts of ligusticum wallichii, 18-35 parts of paris polyphylla, 18-35 parts of scorpio, 12-18 parts of rhizoma curcumae, 10-20 parts of nidus vespae, 18-35 parts of cortex acanthopanacis and 10-16 parts of folium artemisiae argyi. The medicine has the effects of dispelling wind and eliminating dampness, eliminating cold to stop pain, promoting blood circulation to remove blood stasis, relieving rigidity of muscles and activating collaterals as well as reinforcing qi and nourishing blood, is good in absorption effect, definite in effect, safe, reliable and free from toxic and side effects, achieves the aim of treating both symptoms and root causes, and has good treatment effect on the rheumatic arthritis.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of medicine for the treatment of rheumatic arthritis and preparation method thereof.
Background technology
Rheumatic arthritis is that a kind of non-infectious inflammation is main systemic autoimmune disease take the joint, can repeatedly show effect and involves heart.Clinical miserable take joint and muscle migration, heavily work, pain is as feature, belongs to allergic disease.Rheumatic arthritis is the modal a kind of clinical disease of rheumatic fever, and the rheumatic arthritis onset is more anxious, and mainly with febris acuta and arthralgia onset, typical case's performance is slight or the moderate heating, migratory polyarthritis, and the joint of getting involved is take large joint as main.Begin to invade and the joint of the lower extremity person accounts for 85%, knee joint and ankle joint are the most common.Secondly be shoulder, elbow and wrist, the little joint of hands and foot is rare, arthropathy is multiple and migration, commonly be transferred to another joint by a joint, the local joint inflammation is obvious, that performance has is red, swollen, hot, bitterly, tenderness and limitation of activity, persistent period is not long, be everlasting and disappear voluntarily in a few days, do not stay sequela, but the Chang Fanfu outbreak.Atypical patient only has arthralgia and without other inflammation performances, myocarditis then can occur even leave over valve disorder if active rheumatism affects heart.
At present, not yet fully clear and definite for the mechanism of rheumatism, modern medicine to it also without prevention and treatment method preferably.Yet motherland's medical science has obvious advantage aspect the preventing and treating of rheumatism.The traditional Chinese medical science thinks, wind, the exopathogen invasion and attack human body such as cold, wet, hot, the impatency meridians, QI and blood can not pass unimpeded, cause muscles and bones, joint etc. ache, numb, weighing, activities adverse, even arthroncus is scorching hot, so that stagnation of QI and blood may bring about pain." interior warp " thought, plain body deficiency of qi and blood, and wind, cold, wet three gas heterozygosis are invaded human body in an opponent's defence, and multiple abscess muscles and bones blood vessels are fought and are tied in the joint, are the Etiological pathogenesis of numbness disease.So the heresy that wind and cold is damp and hot is this pathogenetic external condition, and insufficiency of vital energy and blood, battalion defending the intrinsic factor that imbalance is only primary disease.The invention provides a kind of medicine for the treatment of rheumatic arthritis, it is take functions dispelling wind and clearing away cold, removing dampness, benefiting QI for activating blood circulation collateral dredging as rule for the treatment of, and effect is obvious not in the past this type for the treatment of by Chinese herbs of solution, the slower problem that takes effect, effective, instant effect, has effect remarkable, the advantage that drug effect is definite.
Summary of the invention
The invention provides a kind of medicine for the treatment of rheumatic arthritis and preparation method thereof, medicine of the present invention can bone and muscle strengthening, invigorating the liver and kidney, make local vascular dilation, blood fortune strengthens, metabolism strengthens, immunity improves, thereby makes pain relief, play strengthening the body resistance, relaxing muscles and tendons and activating QI and blood in the collateral, the removing dampness of dispeling the wind, enrich blood invigorate blood circulation, the effect of reducing swelling and alleviating pain.
For achieving the above object, technical scheme of the present invention is implemented as follows:
A kind of medicine for the treatment of rheumatic arthritis, raw material composition and the parts by weight of making described effective ingredient are:
10～20 parts of 15～30 portions of Fructus Chaenomeliss of 12～18 parts of Radix Dipsacis of 12～18 parts of Herba Saussureae Involuerataes of Herba Lycopodii
Very heavy 18～35 parts of 18～35 portions of Scorpios of 10～20 parts of Rhizoma Paridis of 15～30 parts of Rhizoma Chuanxiongs of dialling
10～16 parts of 18～35 portions of Folium Artemisiae Argyis of 10～20 parts of Cortex Acanthopanciss of 12～18 parts of Nidus Vespae of Rhizoma Curcumae.
Raw material composition and the parts by weight of making described effective ingredient are:
13～18 parts of 20～25 portions of Fructus Chaenomeliss of 14～17 parts of Radix Dipsacis of 14～17 parts of Herba Saussureae Involuerataes of Herba Lycopodii
Very heavy 22～28 parts of 22～28 portions of Scorpios of 13～18 parts of Rhizoma Paridis of 20～25 parts of Rhizoma Chuanxiongs of dialling
12～15 parts of 22～28 portions of Folium Artemisiae Argyis of 13～18 parts of Cortex Acanthopanciss of 14～17 parts of Nidus Vespae of Rhizoma Curcumae.
Raw material composition and the parts by weight of making described effective ingredient are:
16 parts of 23 portions of Fructus Chaenomeliss of 15 parts of Radix Dipsacis of 15 parts of Herba Saussureae Involuerataes of Herba Lycopodii
Very heavy 25 parts of the 25 portions of Scorpios of 16 parts of Rhizoma Paridis of 23 parts of Rhizoma Chuanxiongs of dialling
14 parts of 25 portions of Folium Artemisiae Argyis of 16 parts of Cortex Acanthopanciss of 15 parts of Nidus Vespae of Rhizoma Curcumae.
A kind of preparation method for the treatment of the medicine of rheumatic arthritis comprises following processing step:
(1) with each 50% mixing of Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis weight, carry out pulverization process behind the mix homogeneously, porphyrize is crossed 120 order fine powders, and is for subsequent use.
(2) with adding in the container behind remaining Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis and very heavy group, Rhizoma Chuanxiong, Rhizoma Paridis, Scorpio, Rhizoma Curcumae, Nidus Vespae, Cortex Acanthopancis, the Folium Artemisiae Argyi mix homogeneously, add the water of 8 times of amounts, extracted filtration, taking liquid 2～3 hours; The water that adds again 6 times of amounts in remaining residue extracted 1～2 hour, filtered taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of 60 ℃ of lower relative densities 1.10～1.15, drying under reduced pressure.
(3) gained fine powder in the step (1) is added step (2) and make mix homogeneously in the thick paste, after 50～60 ℃ of dryings, be ground into 120 purpose medicated powder, namely get the active ingredient raw materials medicine of product of the present invention, in this crude drug, add pharmaceutic adjuvant and be prepared into various pharmaceutical formulations.
The property of medicine of the used Chinese medicine of the present invention is as follows:
Herba Lycopodii: hardship, cold.Return liver, spleen channel.Expelling wind and removing dampness is arranged, the effect of relaxing muscles and tendons and activating QI and blood in the collateral.Be used for rheumatic ostalgia, grain contracture, fracture, traumatic injury." treasure-house " carries: " strangle wise sweet in the mouth, hardship, suffering, effect is controlled wind heat, plague fever when removing, and effect is slow, can be in harmonious proportion and occlusion disorder, controls ageing diseases, rheumatism.”
Herba Saussureae Involueratae: warm in nature, lightly seasoned acid, nontoxic.Enter liver,spleen,kidney three warps.Tonifying YANG, regulating menstruation, the effect of hemostasis are arranged except cold." the Chinese Herbal Medicine in Xinjiang handbook is carried: " restore menstrual flow and invigorate blood circulation, bone and muscle strengthening promotes uterine contraction.Treating rheumatic arthritis, women's cold and pain in the lower abdomen, amenorrhea, placenta retention, measles without adequate eruption, lung cold cough, sexual impotence.”
Radix Dipsaci: bitter in the mouth, suffering, slightly warm in nature.Return liver, kidney channel.Invigorating the liver and kidney is arranged; Bone and muscle strengthening, blood circulation regulating, continuous folding is hindered, and ends the effect of metrorrhagia.Be used for aching pain in waist and back, podomere flaccidity syndrome and arthralgia syndrome, fall pounce on wound, decrease muscle folding bone, red, metrorrhagia is leaked in fetal movement, seminal emission, leukorrhagia, carbuncle skin ulcer are swollen.Carry " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " meridians decide in tonifying liver, bone and muscle strengthening, end in the warp (muscles and bones) and ache, and are antiabortive, control the married woman leucorrhea, tissue regeneration promoting blood, and removing blood stasis with potent drugs blood, the stillborn fetus that falls, the cough-relieving hemoptysis of coughing is controlled red white turbid urine.”
Fructus Chaenomelis: property is put down, is slightly cold, sweet in the mouth.Return liver, spleen channel.The suppressing the hyperactive liver Shujin is arranged, and the effect of stomach function regulating removing dampness swells and ache for rheumatic arthralgia, the heavy pain of waist knee joint acid, the contracture of muscle arteries and veins, beriberi.Fructus Chaenomelis has preferably relaxing muscles and tendons and activating QI and blood in the collateral effect, and the energy removing dampness, and by the dispelling the wind and dampness pathogens arthralgia pain is commonly used, muscle arteries and veins contracture person is key medicine particularly." book on Chinese herbal medicine newly organized " carries: " blood be that heat is compeled, myospasm and pain, and gas is humidity hysteresis, and muscular atonia is and soft, and Fructus Chaenomelis removing heat from blood receipts are taken off, therefore can and control.”
Very heavy group: sweet, puckery flat.Return liver, kidney channel.Relaxing muscles and tendons and activating QI and blood in the collateral is arranged, the effect of strong waist knee joint.The dispelling the wind and dampness pathogens osteodynia, lumbar muscle strain, the son foot is aching and limp, and osteopatia sprains etc. also can be treated beriberi." medical material compilation of data " carries: " curing rheumatism, pain relieving.”
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting is arranged, the effect of wind-expelling pain-stopping.Be used for pacifying nerve, positive wind syndrome of head headache, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia." Japan hanako materia medica " carries: " control a wind cutting, all gas, all strains, all blood are mended five kinds of over strain, and strengthening bone and muscle is transferred many arteries and veins, and broken crux stagnated blood is supported fresh blood, puts on flesh.”
Rhizoma Paridis: be slightly cold hardship.Return Liver Channel.Heat-clearing and toxic substances removing is arranged, reducing swelling and alleviating pain, the effect of cool liver arresting convulsion.Be used for furuncle too fat to move, laryngopharynx swelling and pain, venom falls and pounces on the pain of injury, convulsion with spasms." book on Chinese herbal medicine converges and says " carries: " Rhizoma Paridis, removing heat from blood removes wind, separates the medicine of carbuncle poison also.”
Scorpio: suffering, flat; Poisonous.Return Liver Channel.Endogenous wind stopping spasmolytic is arranged, dispersing pathogen accumulation, the effect of removing obstruction in the collateral to relieve pain.Be used for infantile convulsion, the tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula." king Chinese catalpa medicine solution " carries: " wear muscle deep, by the wet wind that removes.”
Rhizoma Curcumae: hot, bitter, temperature.Return liver, spleen channel.Removing blood stasis is arranged, the effect of promoting the circulation of QI to relieve pain." medicineization justice " carries: " fluffy art acrid in the mouth is strong, specializes in the blood in the gas, and the main removing mass heavily fortified point that disappears removes to gather the addiction piece, and the amenorrhea blood stasis is pounced on newspaper pain.”
Nidus Vespae: sweet, flat.Return the stomach warp.Dispel the wind counteracting toxic substances, parasite killing, pain relieving, antianaphylactic effect." choosing of Simao, Yunnan Chinese herbal medicine " carries: " relaxing muscles and tendons and activating QI and blood in the collateral, method rheumatism, diuresis.Treating rheumatic arthritis, waist knee joint arthralgia chiefly caused by damp pathogen, oedema due to nephritis.”
Cortex Acanthopancis: hot, bitter, temperature.Return liver, kidney channel.Wind-damp dispelling is arranged, invigorating the liver and kidney, bone and muscle strengthening, the effect of the arteries and veins of invigorating blood circulation.Be used for that anemofrigid-damp arthralgia, lumbocrural pain, muscles and bones flaccidity are soft, children's's walking retardation in children, body void are frail, traumatic injury, fracture, edema, beriberi, uncontrolled urination are itched." detailed outline " carries: " dispelling the wind and dampness pathogens flaccidity syndrome and arthralgia syndrome, strengthening bone and muscle.”
Folium Artemisiae Argyi: hot, bitter, temperature; Slightly poisonous.Return the liver,spleen,kidney warp.Dispersing cold for relieving pain is arranged, the effect of warming the meridian for stopping bleeding.Dispelling the wind and dampness pathogens arthromyodynia commonly used, arthralgia." detailed outline " carries: " warming middle-JIAO, by cold, dehumidifying.”
The present invention develops meticulously according to the theory of traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling.All medicines share in the side, and to rheumatic arthritis local pain, swelling, the muscle arteries and veins stasis of blood stagnates, numb limbs and tense tendons, and soreness of waist and knee joint etc. can play relaxing muscles and tendons to promote blood circulation, coronary circulation-promoting pain-relieving, the function of reinforcing the kidney to strengthen the bone.Herba Lycopodii expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral in the side are to eliminate external heresy; Herba Saussureae Involueratae invigorating the liver and kidney, bone and muscle strengthening, kidney-replenishing, accent punching are appointed, and make the healthy energy internal memory, and activating YANG and prormoting functioning of QI promotes impaired joint tissue tissue regeneration promoting; Radix Dipsaci, Fructus Chaenomelis, the very heavy group of stomach function regulating removing dampness, blood circulation regulating are used for promoting impaired joint blood circulation that the nutrition of supply joint recovers impaired function of joint; Rhizoma Chuanxiong, Rhizoma Paridis, Scorpio, Rhizoma Curcumae heat-clearing and toxic substances removing, promoting the circulation of QI to relieve pain are eliminated local inflammation; Nidus Vespae, Cortex Acanthopancis, Folium Artemisiae Argyi warming the meridian for stopping bleeding, antiallergic suppresses humoral immunization.All medicine compatibilities bring out the best in each other, and play altogether expelling wind and removing dampness, dispersing cold for relieving pain, blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, the effect of benefiting QI and nourishing blood.
The present invention adopts the Chinese crude drug of different properties, has carried out the science compatibility, and is easy to use, safe and reliable, has no side effect, and reaches the purpose for the treatment of both the principal and secondary aspects of a disease, and rheumatic arthritis is had good therapeutic effect.
The specific embodiment
Below in conjunction with specific embodiment the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
Herba Lycopodii 15g Herba Saussureae Involueratae 15g Radix Dipsaci 23g Fructus Chaenomelis 16g
Very heavy group of 23g Rhizoma Chuanxiong 16g Rhizoma Paridis 25g Scorpio 25g
Rhizoma Curcumae 15g Nidus Vespae 16g Cortex Acanthopancis 25g Folium Artemisiae Argyi 14g.
The processing step of process for preparing medicine of the present invention is:
(1) with each 50% mixing of Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis weight, carry out pulverization process behind the mix homogeneously, porphyrize is crossed 120 order fine powders, and is for subsequent use.
(2) with adding in the container behind remaining Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis and very heavy group, Rhizoma Chuanxiong, Rhizoma Paridis, Scorpio, Rhizoma Curcumae, Nidus Vespae, Cortex Acanthopancis, the Folium Artemisiae Argyi mix homogeneously, add the water of 8 times of amounts, extracted filtration, taking liquid 2 hours; The water that adds again 6 times of amounts in remaining residue extracted 1 hour, filtered taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of 60 ℃ of lower relative densities 1.10～1.15, drying under reduced pressure.
(3) gained fine powder in the step (1) is added step (2) and make mix homogeneously in the thick paste, after 50～60 ℃ of dryings, be ground into 120 purpose medicated powder, namely get the active ingredient raw materials medicine of product of the present invention, in this crude drug, add pharmaceutic adjuvant, be prepared into capsule according to routine techniques.
Usage and dosage: every day 3 times, each 3～6g, warm water delivery service in half an hour after meal, 10 days is a course for the treatment of, and common 1～2 course for the treatment of is effective, and pertinacious disease needs 3～4 courses for the treatment of.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
Herba Lycopodii 12g Herba Saussureae Involueratae 12g Radix Dipsaci 15g Fructus Chaenomelis 10g
Very heavy group of 15g Rhizoma Chuanxiong 10g Rhizoma Paridis 18g Scorpio 18g
Rhizoma Curcumae 12g Nidus Vespae 10g Cortex Acanthopancis 18g Folium Artemisiae Argyi 10g.
The processing step of process for preparing medicine of the present invention is:
(1) with each 50% mixing of Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis weight, carry out pulverization process behind the mix homogeneously, porphyrize is crossed 120 order fine powders, and is for subsequent use.
(2) with adding in the container behind remaining Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis and very heavy group, Rhizoma Chuanxiong, Rhizoma Paridis, Scorpio, Rhizoma Curcumae, Nidus Vespae, Cortex Acanthopancis, the Folium Artemisiae Argyi mix homogeneously, add the water of 8 times of amounts, extracted filtration, taking liquid 2.5 hours; The water that adds again 6 times of amounts in remaining residue extracted 1.5 hours, filtered taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of 60 ℃ of lower relative densities 1.10～1.15, drying under reduced pressure.
(3) gained fine powder in the step (1) is added step (2) and make mix homogeneously in the thick paste, after 50～60 ℃ of dryings, be ground into 120 purpose medicated powder, namely get the active ingredient raw materials medicine of product of the present invention, in this crude drug, add pharmaceutic adjuvant, be prepared into granule according to routine techniques.
Usage and dosage: every day 3 times, each 3～6g, warm water delivery service in half an hour after meal, 10 days is a course for the treatment of, and common 1～2 course for the treatment of is effective, and pertinacious disease needs 3～4 courses for the treatment of.
Embodiment 3
The raw material of effective ingredient of the present invention forms and parts by weight are:
Herba Lycopodii 18g Herba Saussureae Involueratae 18g Radix Dipsaci 30g Fructus Chaenomelis 20g
Very heavy group of 30g Rhizoma Chuanxiong 20g Rhizoma Paridis 35g Scorpio 35g
Rhizoma Curcumae 18g Nidus Vespae 20g Cortex Acanthopancis 35g Folium Artemisiae Argyi 16g.
The processing step of process for preparing medicine of the present invention is:
(1) with each 50% mixing of Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis weight, carry out pulverization process behind the mix homogeneously, porphyrize is crossed 120 order fine powders, and is for subsequent use.
(2) with adding in the container behind remaining Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis and very heavy group, Rhizoma Chuanxiong, Rhizoma Paridis, Scorpio, Rhizoma Curcumae, Nidus Vespae, Cortex Acanthopancis, the Folium Artemisiae Argyi mix homogeneously, add the water of 8 times of amounts, extracted filtration, taking liquid 3 hours; The water that adds again 6 times of amounts in remaining residue extracted 2 hours, filtered taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of 60 ℃ of lower relative densities 1.10～1.15, drying under reduced pressure.
(3) gained fine powder in the step (1) is added step (2) and make mix homogeneously in the thick paste, after 50～60 ℃ of dryings, be ground into 120 purpose medicated powder, namely get the active ingredient raw materials medicine of product of the present invention, in this crude drug, add pharmaceutic adjuvant, be prepared into tablet according to routine techniques.
Usage and dosage: every day 3 times, each 3～6g, warm water delivery service in half an hour after meal, 10 days is a course for the treatment of, and common 1～2 course for the treatment of is effective, and pertinacious disease needs 3～4 courses for the treatment of.
Clinical data:
1, case is selected
Rheumatic arthritis patient's 400 routine clinical observations of selecting my institute or outer court to make a definite diagnosis, patient is divided into two groups at random, treatment group 200 examples, wherein male's 102 examples, women's 98 examples, 18～64 years old age, 46.8 years old mean age, the shortest person of the course of disease 6 months, elder 28 years, average 8.2 years.Matched group 200 examples, male's 105 examples wherein, women's 95 examples, 17～62 years old age, 44.2 years old mean age, the course of disease 8 months～23 years, average 7.9 years.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, the treatment group patient takes medicine of the present invention, adult every day 3 times, and each 3～6g, warm water delivery service in half an hour after meal, 10 days is a course for the treatment of, and common 1～2 course for the treatment of is effective, and pertinacious disease needs 3～4 courses for the treatment of.Matched group is taken phenylbutazone tablet, each 0.1～0.2g, every day 3 times, oral meal.
3, efficacy determination:
(1) produce effects: body constitution strengthens, with it energetically; Red, swollen, hot, the pain of joint and soft tissue are obviously alleviated; Morning, deadlock alleviated; Joint deformity is alleviated.
(2) effective: body constitution strengthens, with it energetically; Red, swollen, hot, the pain in joint are alleviated to some extent.
(3) invalid: disease is unchanged.
4, result
Take in the treatment group of medicine of the present invention produce effects 145 examples, effective 43 examples, invalid 12 examples, total effective rate 94%.
Produce effects 43 examples in the matched group, effective 90 examples, invalid 67 examples, total effective rate 66.5%.
Above result's demonstration, the treatment group total effective rate is apparently higher than matched group.
Model case is given an example:
1, Lee * *, woman, 48 years old, secondary school teachers.The whole body arthralgia was shown effect 6 years repeatedly, and limbs are heavy, and rise stiff morning, and the joint joint stuffiness is met cold rnning and weighed.Clinical diagnosis: it is sick that rheumatic arthritis, card belong to cold warm numbness.Take medicine of the present invention after 30 days, play stiff all diseases in arthralgia, morning and disappear, functional rehabilitation, chemical examination takes stopgap measures all normal.Follow up a case by regular visits to so far not recurrence.
2, in vain * *, man, 36 years old, Enterprise Staff.Had a cold before 5 years, be afraid of cold at that time, arthritis is used the Western medicine pain relieving, cures the symptoms, not the disease, whenever cloudy day, rainy, cold day two fingers, toe, double knee joint pain, disease increased the weight of in nearly 1 year, forefinger, the existing distortion of middle articulations digitorum manus, and upper arm can not be gone up act, back and whole body arthralgia overcast and rainyly enter after the winter especially hurt like hell.The performance of this patient clinical meets the rheumatic arthritis symptom, and the cause of disease is due to the overworked weakness of health, and sick for a long time imbalance was taken medicine of the present invention after 40 days again, and the aversion to wind arthralgia of being afraid of cold transference cure is followed up a case by regular visits to, without recurrence.
3, recklessly * *, woman, 42 years old, civil servant.Arthralgia is diagnosed as rheumatic arthritis in hospital for many years, rear long-term steroid, analgesic, and attempted various naturopathy methods, and effect is all not obvious, and increase in the joint of getting involved, handicapped.Taking medicine of the present invention after 20 days, symptom takes a turn for the better, continue to take 10 days after, transference cure, activity freely, not recurrence.
4, congratulate * *, man, 29 years old, builder.Begin to occur lumbago without obvious inducement the year before, activity more very, lumbago is alleviated after several days, pain and double knee joint, after gradually be developed to the duplex joint, carpal joint and two ankle joint are migration, the pain joint motion is unfavorable, is diagnosed as rheumatic arthritis.Take medicine of the present invention after one month, the symptom complete obiteration, pain disappears, and livelihood restoration is normal.
Claims (4)
1. medicine for the treatment of rheumatic arthritis is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
10～20 parts of 15～30 portions of Fructus Chaenomeliss of 12～18 parts of Radix Dipsacis of 12～18 parts of Herba Saussureae Involuerataes of Herba Lycopodii
Very heavy 18～35 parts of 18～35 portions of Scorpios of 10～20 parts of Rhizoma Paridis of 15～30 parts of Rhizoma Chuanxiongs of dialling
10～16 parts of 18～35 portions of Folium Artemisiae Argyis of 10～20 parts of Cortex Acanthopanciss of 12～18 parts of Nidus Vespae of Rhizoma Curcumae.
2. a kind of medicine for the treatment of rheumatic arthritis according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
13～18 parts of 20～25 portions of Fructus Chaenomeliss of 14～17 parts of Radix Dipsacis of 14～17 parts of Herba Saussureae Involuerataes of Herba Lycopodii
Very heavy 22～28 parts of 22～28 portions of Scorpios of 13～18 parts of Rhizoma Paridis of 20～25 parts of Rhizoma Chuanxiongs of dialling
12～15 parts of 22～28 portions of Folium Artemisiae Argyis of 13～18 parts of Cortex Acanthopanciss of 14～17 parts of Nidus Vespae of Rhizoma Curcumae.
3. a kind of medicine for the treatment of rheumatic arthritis according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
16 parts of 23 portions of Fructus Chaenomeliss of 15 parts of Radix Dipsacis of 15 parts of Herba Saussureae Involuerataes of Herba Lycopodii
Very heavy 25 parts of the 25 portions of Scorpios of 16 parts of Rhizoma Paridis of 23 parts of Rhizoma Chuanxiongs of dialling
14 parts of 25 portions of Folium Artemisiae Argyis of 16 parts of Cortex Acanthopanciss of 15 parts of Nidus Vespae of Rhizoma Curcumae.
4. preparation method for the treatment of the medicine of rheumatic arthritis is characterized in that: comprise following processing step:
(1) with each 50% mixing of Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis weight, carry out pulverization process behind the mix homogeneously, porphyrize is crossed 120 order fine powders, and is for subsequent use.
(2) with adding in the container behind remaining Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis and very heavy group, Rhizoma Chuanxiong, Rhizoma Paridis, Scorpio, Rhizoma Curcumae, Nidus Vespae, Cortex Acanthopancis, the Folium Artemisiae Argyi mix homogeneously, add the water of 8 times of amounts, extracted filtration, taking liquid 2～3 hours; The water that adds again 6 times of amounts in remaining residue extracted 1～2 hour, filtered taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of 60 ℃ of lower relative densities 1.10～1.15, drying under reduced pressure.
(3) gained fine powder in the step (1) is added step (2) and make mix homogeneously in the thick paste, after 50～60 ℃ of dryings, be ground into 120 purpose medicated powder, namely get the active ingredient raw materials medicine of product of the present invention, in this crude drug, add pharmaceutic adjuvant and be prepared into various pharmaceutical formulations.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104398757A (en) * | 2014-11-26 | 2015-03-11 | 崔合芳 | Traditional Chinese medicine for treating rheumatoid arthritis and preparation method thereof |
| CN105125995A (en) * | 2015-09-21 | 2015-12-09 | 泰州润泉医药科技有限公司 | Traditional Chinese medicine composition for treating rheumatic arthralgia |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1966018A (en) * | 2006-10-25 | 2007-05-23 | 雒宏志 | Chinese medicinal formulation for treating rheumatic and rheumatoid disease |
| CN101019972A (en) * | 2007-03-14 | 2007-08-22 | 刘树平 | Liquid Chinese medicine for treating rheumatic arthritis and rheumatoil arthritis |
| CN101129946A (en) * | 2007-09-17 | 2008-02-27 | 吴兴保 | Wet rheumatalgia-relieving plaster for traumatic injury and method of producing the same |
-
2012
- 2012-10-10 CN CN201210394974.3A patent/CN102872420B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1966018A (en) * | 2006-10-25 | 2007-05-23 | 雒宏志 | Chinese medicinal formulation for treating rheumatic and rheumatoid disease |
| CN101019972A (en) * | 2007-03-14 | 2007-08-22 | 刘树平 | Liquid Chinese medicine for treating rheumatic arthritis and rheumatoil arthritis |
| CN101129946A (en) * | 2007-09-17 | 2008-02-27 | 吴兴保 | Wet rheumatalgia-relieving plaster for traumatic injury and method of producing the same |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104398757A (en) * | 2014-11-26 | 2015-03-11 | 崔合芳 | Traditional Chinese medicine for treating rheumatoid arthritis and preparation method thereof |
| CN105125995A (en) * | 2015-09-21 | 2015-12-09 | 泰州润泉医药科技有限公司 | Traditional Chinese medicine composition for treating rheumatic arthralgia |
| CN105125995B (en) * | 2015-09-21 | 2019-01-01 | 泰州润泉医药科技有限公司 | A kind of Chinese medicine composition for treating rheumatic arthralgia |
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