CN1966018A - Chinese medicinal formulation for treating rheumatic and rheumatoid disease - Google Patents
Chinese medicinal formulation for treating rheumatic and rheumatoid disease Download PDFInfo
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- CN1966018A CN1966018A CNA2006101048107A CN200610104810A CN1966018A CN 1966018 A CN1966018 A CN 1966018A CN A2006101048107 A CNA2006101048107 A CN A2006101048107A CN 200610104810 A CN200610104810 A CN 200610104810A CN 1966018 A CN1966018 A CN 1966018A
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Abstract
The invention discloses a pharmaceutical composition for treating rheumatism and rheumatoid disease, wherein the constituents include black-tail snake, gastrodia tuber, Clematis chinensis, pubescent angelica root, notopterygium root, ledebouriella root, speranskia herb, Loranthus mulberry mistletoe, cortex acanthopanacis, root of herbaceous peony, earthworm, achyranthes and cyathula root, dipsacus root, drynaria, east Asian tree fern rhizome, broomrape, psoralea fruit, eucommia bark, deer horn gum, homalomena rhizoma, hairy birthwort, batryticated silkworm, dragon's blood resin, Moghania philippinensis, futokadsura stem, rhizoma dioscoreae hypoglaueae, herba siehesbeckiae, root of red rooted saliva, buck grass, orienavine, anisetree bark, Japanese yam, pawpaw, large-leaf gentian root, and Tripterygium wilfordii 120-150, prepared Sichuan aconite root, prepared wild aconite root, processed semen strychni each 280-320g, Chinese angelica root, red ginseng, astragalus root each 140-180, pipe-fish, wood louse, buthus martensi karsch, Chinese ephedra, licorice root each 70-80, safflower, Ligusticum wallichii, notoginseng, cassia twig, hornet nest 100-120, centipede 50-60, asaryl, aniseed 80-100 and Aconitum pendulum Busch 15-20.
Description
Technical field
The present invention relates to a kind of is the pharmaceutical preparation of raw material with animals and plants, particularly a kind of rheumatism, rheumatoid Chinese medicine preparation of being used for the treatment of.
Background technology
Rheumatism is one group of disease of the musculoskeletal system based on Drug therapy, and it comprises: the disease of joint that the diffusivity connective tissue disease and the various cause of disease cause and periarticular soft tissues, muscle, tendon, ligament etc., and based on the big arthralgia of extremity.
Rheumatoid arthritis is one, and to involve joint on every side be the main struvite autoimmune disease of multisystem, its distinctive symptom is symmetry, a plurality of joint chronic inflammation pathological changes on every side, clinical manifestation is the arthralgia of getting involved, swelling, function reduction, and pathological changes become to continue, episode process repeatedly.Its pathology is chronic synovitis, invades and the cartilage and the bone of lower floor, causes destruction of joint.
Clinical manifestation: 80% was fallen ill in 35-50 year, and the women is 3 times of male.Characteristics are with slowly and concealment mode onset.Joint performance has 3 features: 1. morning deadlock: night and morning ankylosis such as gluing.2. arthralgia: the most common is wrist, metacarpal bone joint, secondly is toe, knee joint, ankle, elbow, shoulder joint.Having a cold swells and ache increases the weight of.3. joint deformity: be more common in patients with terminal.Flexion joint deformities such as finger, wrist, foot, toe.Amyotrophy around the joint, spasm then make deformity even more serious.
The traditional Chinese medical science thinks that rheumatism, rheumatoid disease are all under the condition because of multiple factors such as human righteousness's deficiency, disharmony of nutrient QI with defensive QI, deficiency of both QI and blood, internal organs weakness or a certain factor, wind-cold damp pathogen is taken advantage of a weak point, invade collaterals of human, joint, muscle, skeleton etc. and locate, cause above-mentioned clinical manifestation.Primary disease is influenced by weather cold also and outbreak repeatedly, and the obstinate disease person has caused the QI and blood heavy losses, causes the stiff deformity of extremities joint, limitation of activity, pain unbearably, even disability brings great misery to the patient.
Not clear and definite as yet about rheumatism and the rheumatoid cause of disease and pathogeny, think relevant at present with autoimmune.It is main that most of medical institutions take pain management, takes a large amount of ibuprofens, diclofenac, indometacin etc., and the acute stage patient who has takes a large amount of hormones and controls, and mitigation symptoms finally fails to break away from the misery that this disease is brought.
Summary of the invention
The object of the present invention is to provide a kind of rheumatism, rheumatoid Chinese medicine preparation of being used for the treatment of.
Compound recipe rheumatism health concentrated pill of the present invention, through three more than ten years concentrate on studies and clinical several thousand routine patients' treatment practice filters out more than 50 kind of natural Chinese medicines, adopting meticulous processes is sweet refining type concentrated pill.This prescription pharmacopoeia class and dosage are as follows: Zaocys, Rhizoma Gastrodiae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Clematidis, Daphne giraldii Nitsche, Herba speranskiae tuberculatae, Herba Taxilli, Cortex Acanthopancis, the Radix Paeoniae Alba, Pheretima, Radix Cyathulae, Radix Dipsaci, Rhizoma Drynariae, Rhizoma Cibotii, Herba Cistanches, Fructus Psoraleae, the Cortex Eucommiae, Colla cornus cervi, Rhizoma Homalomenae, Herba Aristolochiae Mollissimae, Bombyx Batryticatus, Sanguis Draxonis, very heavy group, Caulis Piperis Kadsurae, Rhizoma Dioscoreae Septemlobae, Herba Siegesbeckiae, Radix Salviae Miltiorrhizae, Herba Lycopodii, Caulis Sinomenii, Cortex Illicii, Rhizoma Dioscoreae Nipponicae, Fructus Chaenomelis, Radix Gentianae Macrophyllae, each 120-150 of Radix Tripterygii Wilfordii; Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, each 280-310 of Semen Strychni (processed); Radix Angelicae Sinensis, Radix Ginseng Rubra, each 140-180 of Radix Astragali Preparata; Solenognathus, Eupolyphaga Seu Steleophaga, Scorpio, Herba Ephedrae, each 70-80 of Radix Glycyrrhizae; Flos Carthami, Rhizoma Chuanxiong, Radix Notoginseng, Ramulus Cinnamomi, each 110-120 of Nidus Vespae; Scolopendra 50-60; Herba Asari, each 90-100 of Radix Alangii; Radix aconiti szechenyiani 15-20.
In the prescription of the present invention, the cold dehumidifying of dispeling the wind of Zaocys, Radix Aconiti Preparata, CHENGLINGXIAN, Radix Aconiti Kusnezoffii Preparata, Herba Taxilli, Cortex Acanthopancis, Rhizoma Homalomenae, Radix Cyathulae, Ramulus Cinnamomi, very heavy group, Herba speranskiae tuberculatae, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Daphne giraldii Nitsche, Radix Saposhnikoviae, Herba Ephedrae, Herba Asari, Fructus Chaenomelis, Radix Gentianae Macrophyllae, Herba Aristolochiae Mollissimae, Caulis Piperis Kadsurae, Radix Tripterygii Wilfordii, Herba Lycopodii, Rhizoma Dioscoreae Septemlobae, Herba Siegesbeckiae, Caulis Sinomenii, Cortex Illicii, Rhizoma Dioscoreae Nipponicae, Radix Alangii, Semen Strychni (processed), promoting the flow of QI in the collateral by warming the meridian, wind resistance is cold, antiinflammatory, analgesia, and can suppress the rheumatism inflammatory hyperplasia, alleviate synovial tissue's inflammatory reaction.The blood of building up one's health by taking tonic, activating blood circulation to dissipate blood stasis such as Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Flos Carthami, Sanguis Draxonis, Radix Notoginseng, blood circulation promoting, improve the nutrition of extremities joint, muscle, skeleton diseased region, repair by the destructive osteoarthrosis of rheumatism and periarticular muscle, tendon and ligament.Medical instruments such as Rhizoma Gastrodiae, Bombyx Batryticatus, Scorpio, Pheretima, Scolopendra have the endogenous wind stopping relieving convulsion, removing obstruction in the collateral to relieve pain, and the wind-damp dispelling Shujin, treatment rheumatic arthralgia and numb limbs and tense tendons, diseases such as contracture of the limbs have good effect.Radix Ginseng Rubra, Radix Astragali strongly invigorating primordial QI and the Wei Zhiqi of battalion, strengthening vital QI to eliminate pathogenic factors, enhancing human body immunity function.Colla cornus cervi, Solenognathus, Rhizoma Drynariae, Radix Dipsaci, Rhizoma Cibotii, the Cortex Eucommiae, Herba Cistanches, Fructus Psoraleae temperature compensation Liver and kidney, bone and muscle strengthening, enhancing human body immunity power.
In a word, this prescription has the cold removing damp and stopping pain that dispels the wind, nourshing blood and promoting blood circulation Shujin, temperature compensation Liver and kidney, bone and muscle strengthening, dredge the meridian passage, strengthening vital QI to eliminate pathogenic factors, and enhancing human body immunity power is repaired ruined osteoarthrosis and periarticular tissue, thereby reaches the curative effect of getting twice the result with half the effort.
Chinese medicine honey refining type concentrated pill of the present invention comprises that at treatment rheumatoid arthritis, rheumatic arthritis and relevant joint disease scapulohumeral periarthritis, sciatica, ankylosing spondylitis, prolapse of lumbar intervertebral disc, lumbar muscle strain, hyperosteogeny, cervical spondylosis, lumbago, skelalgia of rheumatism etc. all have better curative effect.
Usage and consumption: per 8 equal former medicine 3g.The patient with slight symptoms obeys 8-12 grain (3-4.5g) patient with severe symptoms at every turn and obeys 16-24 grain (6-9g), every day 2-3 time at every turn.
The course of treatment: 45 days per courses of treatment, the patient with slight symptoms need obey for 1 course of treatment, and the patient with severe symptoms need obey the 2-3 course of treatment.
Attention:
1, serious hypertension and the careful usefulness of cardiac or follow the doctor's advice;
2, women breast-feeding their children and anemia of pregnant woman forbidding.
The some cases of inventor's in JIUYUE, 1998-2006 year JIUYUE treatment is summarized as follows:
One, diagnostic criteria: with reference to practical internal medicine diagnostic criteria,, have above clinical symptoms and sign, and in conjunction with chemical examination anti-" O ", rheumatoid molecule, inspections such as X-ray film or CT sheet are made a definite diagnosis according to patient's history of present illness.
Two, clinical effectiveness criterion:
Criterion of cure: symptom complete obiterations such as patient's diseased region swells and ache, numbness, the limb activity functional rehabilitation is normal.Relevant chemical examination, X-ray film, CT sheet are normal substantially.
The improvement standard: symptoms such as patient's diseased region swells and ache, numbness obviously alleviate, and the limb function activity is more preceding flexibly.Relevant chemical examination, X-ray film, CT sheet are near normal.
Three, Therapeutic Method:
With rheumatoid arthritis, rheumatic arthritis and the relevant joint disease of accepting for medical treatment, comprise scapulohumeral periarthritis, sciatica, ankylosing spondylitis, prolapse of lumbar intervertebral disc, lumbar muscle strain, hyperosteogeny, cervical spondylosis, lumbago, skelalgia of rheumatism patient, according to the symptom weight, be divided into patient with severe symptoms and patient with slight symptoms's two big classes.
The patient with slight symptoms takes 8-12 grain (the former medicine of 3-4.5g) at every turn; The patient with severe symptoms takes 16-24 grain (the former medicine of 6-9g), every day 2-3 time at every turn.
The course of treatment: 45 days per courses of treatment, the patient with slight symptoms need obey for 1 course of treatment, and the patient with severe symptoms need obey the 2-3 course of treatment.
Four, result's statistics:
Part patient's curative effect from JIUYUE, 1998-2006 year JIUYUE treatment is as follows:
Name of disease example number is cured the invalid cure rate effective percentage that takes a turn for the better
Rheumatoid arthritis 256 181 75-70% 100%
Rheumatic arthritis 165 124 41-75% 100%
Cervical spondylosis 90 57 36 2 63% 97%
Prolapse of lumbar intervertebral disc 84 49 30 5 58% 94%
Lumbar muscle strain 110 86 21 3 78% 97%
Scapulohumeral periarthritis 81 62 16 3 76% 96%
Five, clinical case summary:
Example 1: Zhang, the woman 46 years old, lives the Baoji Chencang District, the peasant.With the both hands articulations digitorum manus swell and ache, the main suit in 3 years of limitation of activity goes to a doctor on November 20th, 2002.The patient once repeatedly went to a doctor with rheumatoid arthritis in Chencang District hospital, clothes Chinese medicine and western medicine unsatisfactory curative effect.Check that the swelling of both hands articulations digitorum manus, moderate deformity are stretched in the wrong limited.Chemical examination: the rheumatoid factor positive.Clap the x sheet: the top light damage of both hands phalanges, the articulations digitorum manus edge is crude and fuzzy, and the joint space is narrow, part articulations digitorum manus gap disappears.Diagnosis: rheumatoid arthritis (late period).Concentrated pill is after 3 days to take compound recipe rheumatism health (trade name of the present invention, down together), and arthralgia alleviates.Took for 2 weeks continuously, swelling and ache is clearly better, and it is more preceding flexibly that finger bends and stretches activity.Treat 3 courses of treatment, patient's arthralgia disappears, and finger is movable to recover normal.Follow up a case by regular visits to not recurrence after 2 years.
Example 2, Zhao so-and-so, man, 32 years old, masonry dam river, Baoji township, workman.Go to a doctor on January 10th, 2004 with the extremity big joint migration main suit who showed effect repeatedly 1 year that swells and ache.It is bad when the patient once repeatedly had an injection, obeys the western medicine fashion with rheumatic arthritis in local hospital.Check: two wrists, elbow, knee joint symmetrical swelling and tenderness.Chemical examination: anti-" o " positive, rheumatoid factor negative.Clap the x sheet: wrist, elbow, knee joint sclerotin do not have destruction, joint surrounding tissue swelling.Diagnosis: chronic rheumatic arthritis.Took compound recipe rheumatism health concentrated pill 7 days, arthralgia alleviates.Serve on for 2 courses of treatment, the extremities joint complete obiteration of swelling and ache.Paying a return visit after 1 year does not have recurrence.
Example 3: journey so-and-so, man, 48 years old, Baoji Weibin District cadre.The main suit who showed effect repeatedly 1 year half with lumbago went to a doctor in December in 1998 on the 9th.The patient once took a turn for the better with the prolapse of lumbar intervertebral disc hospitalization in the People's Hospital, Baoji, recurred after the February of leaving hospital, and lumbago is unable to leave the bed, and the lumbago of having a cold increases the weight of.Check: the obvious tenderness of lumbar vertebra 4-5 vertebral body.CT sheet: prolapse of lumbar intervertebral disc (L4-L5).Take 3 days lumbagos of compound recipe rheumatism health concentrated pill and alleviate, serve on 2 week back patients energy out-of-bed activities, treat recovery from illness 3 courses of treatment.Follow up a case by regular visits to and do not have recurrence in 2 years.
Example 4, Lee so-and-so, woman, 58 years old, Baoji park road sub-district retirement.Go to a doctor on November 25th, 2005 with right shoulder pain, the main suit in 1 year of limitation of activity.The patient once repeatedly went to a doctor in the outpatient service of the hospital of traditional Chinese hospital, Baoji.Do physical therapy with the rheumatic scapulohumeral periarthritis, clothes Chinese medicine and western medicine unsatisfactory curative effect.Check: tenderness is obvious around the right shoulder joint mild swelling, shoulder joint.Shoulder joint is bent and stretched, interior receipts, the equal obstacle of outward turning activity.Take compound recipe rheumatism health concentrated pill after 2 weeks, shoulder joint swelling disappears, and pain obviously alleviates, and treats recovery from illness 2 courses of treatment.Follow up a case by regular visits to after half a year and do not have recurrence.
Example 5, Yang, man, 60 years old.Masonry dam river, Baoji township retired worker.The main suit who aches companion numb half a year with waist went to a doctor on January 4th, 2006.The patient meets wind and cold or tired lumbago increases the weight of.Once it is normal to look into waist CT to the People's Hospital, Baoji, the chemical examination rheumatoid factor negative.Diagnosis: lumbar muscle strain.Take compound recipe rheumatism health concentrated pill after 1 week, lumbago obviously alleviates, and treats lumbago complete obiteration 1 course of treatment.Follow up a case by regular visits to after half a year and do not have recurrence.
The specific embodiment
Medicine of the present invention respectively organizes allocation proportion as follows:
Zaocys, Rhizoma Gastrodiae, Radix Clematidis, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Daphne giraldii Nitsche, Herba speranskiae tuberculatae, Herba Taxilli, Cortex Acanthopancis, the Radix Paeoniae Alba, Pheretima, Radix Cyathulae, Radix Dipsaci, Rhizoma Drynariae, Rhizoma Cibotii, Herba Cistanches, Fructus Psoraleae, the Cortex Eucommiae, Colla cornus cervi, Rhizoma Homalomenae, Herba Aristolochiae Mollissimae, Bombyx Batryticatus, Sanguis Draxonis, very heavy group, Caulis Piperis Kadsurae, Rhizoma Dioscoreae Septemlobae, Herba Siegesbeckiae, Radix Salviae Miltiorrhizae, Herba Lycopodii, Caulis Sinomenii, Cortex Illicii, Rhizoma Dioscoreae Nipponicae, Fructus Chaenomelis, Radix Gentianae Macrophyllae, each 120-150g of Radix Tripterygii Wilfordii; Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, each 280-320g of Semen Strychni (processed); Radix Angelicae Sinensis, Radix Ginseng Rubra, each 140-180g of Radix Astragali Preparata; Solenognathus, Eupolyphaga Seu Steleophaga, Scorpio, Herba Ephedrae, each 70-80g of Radix Glycyrrhizae; Flos Carthami, Rhizoma Chuanxiong, Radix Notoginseng, Ramulus Cinnamomi, each 100-120g of Nidus Vespae; Scolopendra 50-60g; Herba Asari, each 80-100g of Radix Alangii; Radix aconiti szechenyiani 15-20g.
Make sweet refining type concentrated pill following four steps are arranged: 1, when preparation mixed Herba Cistanches, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Ginseng Rubra, the Radix Astragali Preparata of above-mentioned weight, adds water 2000ml, removes slag after decocting 40 minutes, continues heating simmer down to 800ml.2, Colla cornus cervi is smashed to pieces, added in 90 ℃ the concentrated medicine juice and dissolve, make medicine juice be condensed into cream.3, the medicament mixed powder of all the other above-mentioned weight becomes fine flour, adds refined honey with 10:1, and promptly 100g medicated powder adds the 10g refined honey, stirs evenly at an amount of water of adding, will stir evenly in the spissated ointment adding medicine-feeding then.4, machining becomes sweet refining type concentrated pill, and per 8 equal former medicine 3g.
Claims (1)
1, a kind of treatment rheumatism and rheumatoid Chinese medicine preparation is characterized in that making by comprising following parts by weight of Chinese traditional medicine raw material:
Zaocys, Rhizoma Gastrodiae, Radix Clematidis, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Daphne giraldii Nitsche, Herba speranskiae tuberculatae, Herba Taxilli, Cortex Acanthopancis, the Radix Paeoniae Alba, Pheretima, Radix Cyathulae, Radix Dipsaci, Rhizoma Drynariae, Rhizoma Cibotii, Herba Cistanches, Fructus Psoraleae, the Cortex Eucommiae, Colla cornus cervi, Rhizoma Homalomenae, Herba Aristolochiae Mollissimae, Bombyx Batryticatus, Sanguis Draxonis, very heavy group, Caulis Piperis Kadsurae, Bi , Herba Siegesbeckiae, Radix Salviae Miltiorrhizae, Herba Lycopodii, Caulis Sinomenii, Cortex Illicii, Rhizoma Dioscoreae Nipponicae, Fructus Chaenomelis, Radix Gentianae Macrophyllae, each 120-150 of Radix Tripterygii Wilfordii; Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, each 280-320 of Semen Strychni (processed); Radix Angelicae Sinensis, Radix Ginseng Rubra, each 140-180 of Radix Astragali Preparata; Solenognathus, Eupolyphaga Seu Steleophaga, Scorpio, Herba Ephedrae, each 70-80 of Radix Glycyrrhizae; Flos Carthami, Rhizoma Chuanxiong, Radix Notoginseng, Ramulus Cinnamomi, each 100-120 of Nidus Vespae; Scolopendra 50-60; Herba Asari, each 80-100 of Radix Alangii; Radix aconiti szechenyiani 15-20.
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| CNB2006101048107A CN100450526C (en) | 2006-10-25 | 2006-10-25 | Chinese medicinal formulation for treating rheumatic and rheumatoid disease |
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| CNB2006101048107A CN100450526C (en) | 2006-10-25 | 2006-10-25 | Chinese medicinal formulation for treating rheumatic and rheumatoid disease |
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