CN112107617A - Traditional Chinese medicine composition for eliminating ecchymosis and hematoma - Google Patents

Traditional Chinese medicine composition for eliminating ecchymosis and hematoma Download PDF

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CN112107617A
CN112107617A CN201910541930.0A CN201910541930A CN112107617A CN 112107617 A CN112107617 A CN 112107617A CN 201910541930 A CN201910541930 A CN 201910541930A CN 112107617 A CN112107617 A CN 112107617A
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林艳
王新东
陈晓栋
阎芹
刘晓蓉
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Jiangsu Provincial Insititute of Traditional Chinese Medicine
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Abstract

The invention belongs to the field of nursing, and particularly relates to treatment of a forearm ecchymosis hematoma patient after a radial artery interventional operation. The traditional Chinese medicine composition for eliminating ecchymosis comprises the following components: comprises 100-400 parts of safflower, 100-400 parts of salvia miltiorrhiza, 100-400 parts of pseudo-ginseng, 50-250 parts of angelica, 50-250 parts of notopterygium root, 50-250 parts of radix angelicae pubescentis, 20-200 parts of divaricate saposhnikovia root and 20-200 parts of liquorice. The preparation method comprises the following steps: soaking 60% of medicinal materials in 95% ethanol for swelling for 24 hr, placing in a percolation barrel, percolating with 95% ethanol as solvent at flow rate of 2ml/min, and collecting percolate 50 times of the medicinal materials; grinding Borneolum Syntheticum, dissolving in 95% ethanol, mixing with percolate, stirring, sealing, and standing. When in use, the traditional Chinese medicine composition is soaked in alcohol and glycerol for wet dressing, the sterile gauze soaked with the wet medicine is applied to the hematoma part, the wet dressing area exceeds the edge of the hematoma, and a disposable sterile towel is wrapped on the outer layer. Raise the limb 30 degrees below the elbow joint. Keeping the wrist joint straight, and replacing the gauze for 4h for 1 time and 2 times per day for three consecutive days.

Description

Traditional Chinese medicine composition for eliminating ecchymosis and hematoma
Technical Field
The invention belongs to the field of nursing, and particularly relates to traditional Chinese medicine treatment for a forearm ecchymosis hematoma patient after a radial artery interventional operation.
Background
The ecchymosis at the puncture part is caused by the injury of vascular endothelium, the effects of anticoagulant drugs such as heparin and the like in the perioperative period and anti-platelet-accumulation drugs such as aspirin and the like, the patients feel the swelling and pain of operative limbs, and the subcutaneous ecchymosis appears, thereby affecting the rehabilitation. The forearm hematoma refers to a bloody mass formed from bleeding of a punctured radial artery to peripheral soft tissues and can be locally or remotely located at a puncture point of the radial artery; the main manifestations are forearm swelling and pain of postoperative patients; skin temperature is increased, tension is increased, local swelling and tenderness exist, and partial skin of a patient is bluish purple, ecchymosis and the like. The reasons for this are as follows: repeatedly puncturing and damaging the radial artery, particularly too close to the proximal end of the radial artery; compression hemostasis of puncture points is insufficient, and blood seeps from the puncture points to enter the subcutaneous part; and thirdly, the catheter and the guide wire damage the wall of the artery or enter the small branch of the radial artery to cause the injury and hematoma in the entering process. At present, the main treatment means for the ecchymosis hematoma only comprises pressure dressing, local continuous cold compress of magnesium sulfate, external application of mirabilite, mannitol intravenous drip and the like, and the treatment effect is poor.
Disclosure of Invention
Solves the technical problem
Solves the problem that the forearm ecchymosis hematoma of a patient after the radial artery intervention lacks an effective treatment medicament at present.
Adopts the technical proposal
A Chinese medicinal composition for eliminating ecchymosis and hematoma comprises (by weight parts) Carthami flos 100-400, Saviae Miltiorrhizae radix 100-400, Notoginseng radix 100-400, radix Angelicae sinensis 50-250, Notopterygii rhizoma 50-250, radix Angelicae Pubescentis 50-250, radix Saposhnikoviae 20-200, and Glycyrrhrizae radix 20-200.
Further, 200-300 parts of safflower, 200-300 parts of salvia miltiorrhiza, 200-300 parts of pseudo-ginseng, 100-200 parts of angelica, 100-200 parts of notopterygium root, 100-200 parts of radix angelicae pubescentis, 40-150 parts of divaricate saposhnikovia root and 40-150 parts of liquorice.
Further, 240-260 parts of safflower, 240-260 parts of salvia miltiorrhiza, 240-260 parts of pseudo-ginseng, 150-180 parts of angelica, 150-180 parts of notopterygium root, 150-180 parts of radix angelicae pubescentis, 60-100 parts of divaricate saposhnikovia root and 60-100 parts of liquorice.
Further, according to the weight ratio, 60% of medicinal materials and 95% of ethanol are added for soaking and swelling for 24 hours, the mixture is placed in a percolation barrel, 95% of ethanol is used as a solvent, the percolation is carried out at the flow rate of 2ml/min, and the percolation liquid 50 times of the medicinal materials is collected for later use; grinding Borneolum Syntheticum, dissolving in 95% ethanol, mixing with percolate, stirring, sealing, and standing.
The usage is that the traditional Chinese medicine composition is soaked in alcohol and glycerol for wet dressing.
Advantageous effects
The traditional Chinese medicine composition disclosed by the invention has no gastrointestinal reaction after being externally applied to the skin, has small influence on liver and kidney, is convenient to administer, and can accelerate the regeneration of capillary vessels and improve the blood circulation of wound surfaces. Meanwhile, the traditional Chinese medicine composition applied to the affected part has double effects of treatment and psychological nursing. In the formula, the safflower is fragrant and capable of dispersing, enters blood system to promote blood circulation and remove meridian obstruction, and removes blood stasis and relieves pain; the salvia miltiorrhiza is bitter in taste and cool in nature, and can promote blood circulation to remove blood stasis, cool blood and relieve swelling, and the salvia miltiorrhiza are monarch drugs in the formula together. The pseudo-ginseng can dissipate blood stasis, relieve swelling and relieve pain, the Chinese angelica can nourish blood and activate blood, tonify and move as well as relieve pain, and the pseudo-ginseng and the Chinese angelica can strengthen the force of activating blood, relieving pain and relieving swelling by being used as ministerial and ministerial medicines in a prescription. Notopterygium root, rhizoma et radix Notopterygii, having the effect of dispelling wind and relieving pain, is good at treating limb joint pain, and … … is not so good at treating joint pain; du Huo is pungent and bitter with the action of dispersing and drying, fragrant and warm in smell and good at relieving arthralgia, and is used as adjuvant drug. Fang Feng … … is caused by pain in whole body, and Qiang Huo and Fang Feng are combined to release muscles and penetrate exterior so as to facilitate penetration of skin to affected parts; licorice root, radix Glycyrrhizae can relieve spasm and harmonize the other drugs in the recipe. The medicines of the whole formula are combined to play the effects of dissipating blood stasis, reducing swelling, promoting blood circulation and relieving pain.
DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION
General data:
study subjects: in 2018, 6 months to 2019, 5 months, 40 patients with forearm hematoma after the percutaneous radial artery intervention in the department of cardiology in the combined hospital of traditional Chinese and western medicine in Jiangsu province are selected. Inclusion criteria were: (1) first forearm hematoma after radial artery interventional operation; (2) hematoma swelling type I-iii; (3) the forearm skin on the operative side is not damaged. Exclusion criteria: (1) patients with severe coagulation dysfunction are pooled; (2) patients with surgical forearm deformity or trauma; (3) patients with obvious bleeding, ecchymosis or swelling on the punctured side limb before the operation; (4) patients with clear differences in circumference of bilateral forearms; (5) patients suspected of having a periosteum syndrome in need of surgical treatment. Of 40 patients, 27 men and 13 women, aged 31-84 years, have 21 types of I with the diameter less than or equal to 5cm and 14 types of II with the diameter greater than or equal to 5cm and less than or equal to 10cm according to hematoma and swelling classification; the diameter is more than 10cm, the hematoma does not exceed 5 cases of III type of elbow joint, the control group and the test group are randomly divided by a random digital table method, each group comprises 20 cases, and the difference of age, sex, operation scheme, basic disease and the like of two groups of patients has no statistical significance (P is more than 0.05).
The method comprises the following steps:
(1) the medicine components are as follows: the proved formula of the invention, namely the traditional Chinese medicine composition comprises the following medicinal materials: 20g of safflower, 20g of salvia miltiorrhiza, 20g of pseudo-ginseng, 10g of notopterygium root, 10g of radix angelicae pubescentis, 10g of angelica, 5g of divaricate saposhnikovia root and 5g of liquorice.
(2) And (4) a treatment method. The two groups of patients adopt a radial artery special compressor to perform compression hemostasis after the operation. After the subcutaneous ecchymosis hematoma of the forearm is found, performing wet compress on a control group by adopting a traditional treatment method with 50% magnesium sulfate, soaking and swelling an observation group by adding 60% of medicinal material in 95% ethanol for 24 hours, placing the observation group in a percolation barrel, percolating by taking 95% ethanol as a solvent (the flow rate is 2ml/min), and collecting percolate 50 times of the medicinal material for later use; grinding Borneolum Syntheticum, dissolving in 95% ethanol, mixing with percolate, stirring, sealing, and standing. Alcohol and glycerol are soaked in the traditional Chinese medicine composition for wet compress. The two groups of patients are applied to hematoma with sterile gauze soaked with wet compress liquid, the gauze is suitable for preventing dripping, the wet compress area exceeds hematoma edge, and the outer layer is wrapped with disposable sterile towel. Nursing after the intervention operation, and lifting the lower limb of the elbow joint by 30 degrees. Keeping the wrist joint straight, and replacing the gauze for 4h for 1 time and 2 times per day for three consecutive days.
Observation indexes are as follows:
(1) pain was scored. The pain degree is judged by NRS (numerical rating scale, NRS), the numerical grading method represents pain with different degrees by 0-10 points, 0 point is no pain, 1-3 points are mild pain, 4-6 points are moderate pain, and 7-10 points are severe pain.
(2) The swelling degree of the forearm (the circumference of the most swollen affected limb, the circumference of the same part of the healthy limb)/the circumference of the same part of the healthy limb × 100%.
(3) Bluish purple, petechia dissipating time.
The clinical curative effect is as follows:
has obvious effects that the local skin has no thermal sensation, no tenderness or only slight tenderness, the red swelling and pain are obviously relieved, and the skin has wrinkles; the method has the following advantages: the skin heat, red swelling and pain are relieved, the tenderness is obvious, and the skin wrinkles are not obvious; and (4) invalidation: the red swelling, burning and pain feeling of the lesion still exist, the tenderness is obvious, even if the lesion is lightly applied with force, the tenderness is felt, and the skin does not have wrinkles.
Designing a curative effect scale, and recording the following observation indexes in detail:
subcutaneous bleeding sites, area (cm2), presence or absence of induration, area if any (cm2), presence or absence of limb swelling, presence or absence of enlarged pores, presence or absence of skin elasticity, pain (NRS) score, presence or absence of tenderness, score if any (NRS), topical color (□ red; □ cyan; □ purple; □ others), peripheral skin color, were recorded for 5 days in total, starting on the day of surgery.
Figure BDA0002102794840000041
The following data were obtained:
TABLE 1 general data comparison of two groups of patients with forearm hematoma after percutaneous/radial intervention
Figure BDA0002102794840000042
Figure BDA0002102794840000051
TABLE 2 comparison of the results of the wet compress of two groups of patients with forearm hematoma after percutaneous/radial artery intervention
Figure BDA0002102794840000052
TABLE 3 comparison of clinical efficacy of two groups of patients
Group of Number of examples Show effect Is effective Invalidation Total effective rate
Control group 20 8(40%) 4(20%) 8(40%) 60
Observation group 20 13(65%) 6(30%) 1(5%) 95
Figure BDA0002102794840000053
Figure BDA0002102794840000061
Figure BDA0002102794840000062
Figure BDA0002102794840000063
Figure BDA0002102794840000071
The statistical data of the treatment effects of the control group and the experimental group show that the traditional Chinese medicine composition is really effective in treating patients with the ecchymosis and hematoma on the forearm after the radial artery intervention. The traditional Chinese medicine composition disclosed by the invention is easy to apply, easy and convenient to operate and obvious in effect, and the pain of a patient is greatly relieved by combining the traditional Chinese medicine and a clinical care technology.
It is necessary to point out that the traditional Chinese medicine composition can effectively treat ecchymosis hematoma caused by other conditions, such as subcutaneous bruise and pressure wound, based on the formula principle of the traditional Chinese medicine composition.

Claims (4)

1. A traditional Chinese medicine composition for eliminating ecchymoma is characterized in that: comprises 100-400 parts of safflower, 100-400 parts of salvia miltiorrhiza, 100-400 parts of pseudo-ginseng, 50-250 parts of angelica, 50-250 parts of notopterygium root, 50-250 parts of radix angelicae pubescentis, 20-200 parts of divaricate saposhnikovia root and 20-200 parts of liquorice.
2. The traditional Chinese medicine composition for eliminating ecchymoma according to claim 1, which is characterized in that: 200-300 parts of safflower, 200-300 parts of salvia miltiorrhiza, 200-300 parts of pseudo-ginseng, 100-200 parts of angelica, 100-200 parts of notopterygium root, 100-200 parts of radix angelicae pubescentis, 40-150 parts of divaricate saposhnikovia root and 40-150 parts of liquorice.
3. The traditional Chinese medicine composition for eliminating ecchymoma according to claim 1, which is characterized in that: 240-260 parts of safflower, 240-260 parts of salvia miltiorrhiza, 240-260 parts of pseudo-ginseng, 150-180 parts of angelica, 150-180 parts of notopterygium root, 150-180 parts of radix angelicae pubescentis, 60-100 parts of divaricate saposhnikovia root and 60-100 parts of liquorice.
4. The Chinese medicinal composition for eliminating ecchymoma according to any one of claims 1 to 3, which is characterized in that: soaking 60% of medicinal materials in 95% ethanol for swelling for 24 hr, placing in a percolation barrel, percolating with 95% ethanol as solvent at flow rate of 2ml/min, and collecting percolate 50 times of the medicinal materials; grinding Borneolum Syntheticum, dissolving in 95% ethanol, mixing with percolate, stirring, sealing, and standing.
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CN115068532B (en) * 2022-06-22 2023-04-07 深圳市中医院 Medicine for treating forearm swelling after interventional operation and preparation process

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115068532B (en) * 2022-06-22 2023-04-07 深圳市中医院 Medicine for treating forearm swelling after interventional operation and preparation process

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