CN108379173A - A kind of silanol is dispelled pouch composition and application - Google Patents
A kind of silanol is dispelled pouch composition and application Download PDFInfo
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- CN108379173A CN108379173A CN201810455368.5A CN201810455368A CN108379173A CN 108379173 A CN108379173 A CN 108379173A CN 201810455368 A CN201810455368 A CN 201810455368A CN 108379173 A CN108379173 A CN 108379173A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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- Cosmetics (AREA)
Abstract
It dispels pouch composition the invention discloses a kind of silanol, includes the component of following parts by weight：1 10 parts of heavy curtain umbrella maple (HETEROPANAX FRAGRANS) leaf extract, 0.1 1 parts of punarnava (BOERHAVIA DIFFUSA) root extract, 1 10 parts of ascorbic acid methyl-monosilane alcohol pectate.The present invention compounds three together, synergistic, and for orbicular muscle of eye, plump, eye has provided good improvement every the false hernia of interior fat, and eye circumference skin is effectively highlighted while removing pouch, promotes skin elasticity.
Description
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of silanol is dispelled pouch composition and application.
Background technology
With the continuous universal use accelerated with computer of rhythm of life, eye-care has been increasingly becoming people at present most
For the problem, including livid ring around eye, pouch and wrinkle etc. of concern.There are many pouch Crack cause, mainly there is (1) inherent cause：
Primary pouch often has household heredity factors, is more common in young man, and capsula adiposa bulbi crosses mostly its main cause.(2) age factor：
Because of the growth cutis laxa at age and of flaccid muscles and cause pouch, secondary pouch is more common in the middle-aged and the old and is often integrated
The performance of property.(3) living habit：Eye strain factor is that the rest day after tomorrow is bad, sleep is bad, this is also cause pouch one
Reason.Such as what somebody worked below computer for a long time, it is just more more that chance occurs in such pouch.Further more, being exactly
The reasons such as sobbing, various eyes local infections, food, drug or cosmetic allergic contact dermatitis can cause eyelid oedema.Pouch not only makes
People seems aging, tired out, serious or even affect vision.
The method of existing eye haustra -dsipelling has two major classes：One kind is Chinese medicine Endocrine regulating method, by kidney tonifying one kind
Medicine improves intracorporeal organ, promotes endocrine, then improve face table flesh, and to make pouch make moderate progress, the shortcomings that this method is
Treatment time is too long, and Long-term taking medicine is needed to take effect just now, second is that effect unobvious：Another kind of is doctor trained in Western medicine modus operandi, passes through cutout unit
Orbicular muscle of eye and extra skin and socket of the eye is divided to carry out eye haustra -dsipelling every interior fat globule, although this operation is quick, technical difficulty is big,
Dangerous big, costly, surgical procedure people is also painful, and pouch is it is possible to regeneration is formed, and is avoided by vast pouch patient
It is dark.
Invention content
It dispels pouch composition and application the technical problem to be solved in the present invention is to provide a kind of silanol.
The specific technical solution for solving above-mentioned technical problem is as follows：
A kind of silanol is dispelled pouch composition, and the component of following parts by weight is included：Heavy curtain umbrella maple (HETEROPANAX
FRAGRANS) leaf extract 1-10 parts, 0.1-1 parts of punarnava (BOERHAVIA DIFFUSA) root extract, ascorbic acid methyl
1-10 parts of silanol pectate.
Further, the pouch composition of dispelling can also include the component of following parts by weight：Millet starch (CAPSICUM
FRUTESCENS) berry extract 0.1-10 parts, 0.1-10 parts of butcher's broom (RUSCUS ACULEATUS) root extract.
The present invention also provides the application of the pouch composition in preparing cosmetics of dispelling, wherein the pouch combination of dispelling
The dosage of object is the 0.1-10wt% of final products weight.
One kind going pouch lotion, includes the component of following mass percentage：It is the above-mentioned pouch composition 0.1-10% that dispels, pungent
Poly- trimethicone 1-5%, C30-45 alkyl dimethicone 1-5% of base, ring five dimethyl silicone polymer 1-3%,
Different tridecanol myristinate 0.1-5%, tocopherol acetate 0.1-1%, Simulgel NS 0.1-0.5%, hydrolyzed wheat
Albumen 0.1-0.5%, caffeine 0.01-0.1%, PEG-35 lanolin 0.1-0.3%, carbomer 0.1-0.3%, asafoetide
(FERULA ASSA FOETIDA) root extract 0.05-0.3%, arginine PCA 0.1-0.3%, beta carotene 1-5%, Portugal
Grape sugar 0.1-1%, acrylamido copolymer 0.1-0.3%, gluconic acid sodium salt 0.01-0.1%, calcium gluconate 0.01-0.1%,
Calcium aspartate 0.01-0.1%, silica 0.05-0.5%, starch sodium octenyl succinate 0.05-0.5%, polyalcohol 5-
20%, water surplus.
Simulgel NS of the present invention are a emulsion stabilizers for matching BIC Corp.Chemistry is referred to as：Acrylic acid
Hydroxyl ethyl ester/sodium acryloyldimethyl taurate copolymers (and) saualane (and) polysorbate -60, milky white liquid, stabilization
Property it is good, the skin sense that left-hand seat melts is provided, easily absorb.It is capable of providing completely new salubrious skin sense, and there are very strong thickening capabilities.
Further, the polyalcohol be glycerine, it is 1,3-PD, 1,3-BDO, 1,2- hexylene glycols, sorbierite, pungent
At least one of glycol.
In order to ensure that product has longer shelf life, the eyelid cream that goes can also include preservative.
Further, the preservative is potassium sorbate or sodium benzoate.
Further, the additive amount of the potassium sorbate is 0.3-0.7wt%, and the additive amount of the sodium benzoate is 0.3-
0.7wt%.
The present invention has the advantages that：
Silanol of the present invention dispel in pouch composition heavy curtain umbrella maple (HETEROPANAX FRAGRANS) leaf extract activity at
Divide oleanolic acid that can reduce wrinkle of skin, slows down skin irritation；Punarnava (BOERHAVIA DIFFUSA) root extract is lived
Property ingredient punarnava ketone TYR enzyme can be reduced by activating PPAR γ (peroxisome rise in value object activated receptor)
Activity, the substance can reduce the activity of dopa oxidase object, have the effect of bright color simultaneously；Ascorbic acid methyl-monosilane alcohol fruit
Glue acid esters can remove free radical, inhibit casein amino acid activity, make skin recombination and metabolic normalization；Three compounds one
It rises, synergistic, for orbicular muscle of eye, plump, eye has provided good improvement every the false hernia of interior fat, is removing pouch
While effectively highlight eye circumference skin, promote skin elasticity.Further fusion millet starch (CAPSICUM FRUTESCENS) fruit carries
Object and butcher's broom (RUSCUS ACULEATUS) root extract are taken, the effect of pouch can be further promoted, keeps eye circumference skin
Moisture, while eliminating livid ring around eye.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below
Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to
Routine techniques carries out.
, there is following tripartite face in the main reason for pouch formation:1. orbital septum aponeurosis degenerative change；2. orbicular muscle of eye relaxes；③
Cutis laxa, and can aggravate with age.Due to inside and outside institutional framework retrogression and relaxation, in addition eye socket bone
Property structure it is special, that is, be in prosopyle is big, rear end is sharp cone-shaped, under eyeball Orbitalis fat under gravity and attraction of gravitation effect downwards
Bulging is slipped, pouch is gradually formed.Pouch is divided into following three types；(1) orbicular muscle of eye is plump:It shows as being close to the swollen of lower margo palpebrae
It is grand.(2) eye goes out every the false hernia of interior fat, is divided into:(a) the false hernia of capsula adiposa bulbi excess fat goes out, and is more common in young man；
(b) the Orbital septum fat bulging in socket of the eye caused by support structure relaxation, is more common in the middle-aged and the old.(3) the compound performance of above two type.
Functional component involved in the present invention is described further：
Heavy curtain umbrella maple (Heteropanax fragrans (Roxb.) Seem) also known as fragrant heteropanax bark, slender acanthopanax are logical etc., are Araliaceae
Heteropanax magaphanerophytes.Contain oleanolic acid, melaleucic acid, daucosterol etc..Oleanolic acid has anti-inflammatory, anticancer, anti-mistake
Quick, antidepression, antibacterium and antimycotic effect are particularly shown anti-inflammatory gentle by stimulating the physiological activity of skin
The effect of solving skin irritatin.In addition, oleanolic acid stimulation generates collagen the synthesis of the procollagen to play an important role, stimulation
Synthesis to the anti-aging ceramide played an important roll and silk polymeric protein (filaggrin).In addition, it is also with dual
Anti-aging system, the system generation of stimulation collagen and prevent collagen impaired by inhibiting the activity of MMP-1,
MMP-1 is the enzyme for destroying polymerase proteins (such as the collagen generated).As described above, oleanolic acid, which has, reduces wrinkle of skin
Excellent effect.
Yellow carefulnesses are one kind blooming property plants.Zooscopy finds that , Yellow carefulnesses have the anti-inflammatory effect of very Strong；Yellow is careful
Also have the function of eliminating free radical, there is oxidation resistant ability.Punarnava (BOERHAVIA DIFFUSA) root extraction
Object, refined by punarnava root from, wherein effective bioactive molecule-punarnava ketone；The substance can be by activating PPAR γ
(peroxisome increment object activated receptor) reduces the activity of TYR enzyme, which can reduce dopa oxidase object simultaneously
Activity；With bright color, mitigate the effect of color spot, there is certain oil-control effect.
Ascorbic acid methyl-monosilane alcohol pectate effectively optimizes the ability that cell membrane attacks Green Tea Extract, removes freely
Base inhibits casein amino acid activity, makes skin recombination and metabolic normalization.
Millet starch (CAPSICUM FRUTESCENS) berry extract derives from millet starch fruit, is rich in high unit Victoria C, carrot
Element, protein and abundant minerals are a kind of powerful antioxidants, can highlight the eye circumference colour of skin, improve skin counterirritation, have
Good moisture-keeping function.By reducing caloric intake, reducing glyceride level in adipose tissue content and blood, fatty heap is prevented
Product induces 3T3-L1 PECTORAL LIMB SKELETON apoptosis, prevents fat accumulation, additionally also by activating caspase (protease) approach
It can promote local blood circulation, promote the metabolism of skin, skin is made to rejuvenate, pore refining.
Butcher's broom (RUSCUS ACULEATUS) root extract has good activation to cathepsin, can enhance skin
Skin metabolism, has the function of Skin Cell reparation and anti-aging；Luciferase is activated, is illustrated with anti-inflammatory；To saturating
Bright matter acid, which generates, has facilitation, has good moisture retention.It can promote blood circulation, eliminate livid ring around eye.
Embodiment 1
One kind going pouch lotion, includes the component of following mass percentage：Pouch composition 0.1%, the octyl of dispelling poly- three
Methylsiloxane 1%, C30-45 alkyl dimethicones 5%, ring five dimethyl silicone polymer 3%, different tridecanol Pork and beans
Cool acid esters 0.1%, tocopherol acetate 1%, Simulgel NS 0.5%, hydrolyzed wheat protein 0.1%, caffeine 0.1%,
PEG-35 lanolin 0.3%, carbomer 0.1%, asafoetide (FERULA ASSA FOETIDA) root extract 0.3%, arginine
PCA 0.1%, beta carotene 5%, glucose 0.1%, acrylamido copolymer 0.3%, gluconic acid sodium salt 0.01%, glucose
Sour calcium 0.01%, calcium aspartate 0.1%, silica 0.05%, starch sodium octenyl succinate 0.5%, glycerine 2%, 1,3- third
Glycol 3%, water surplus.
The pouch composition of dispelling is by 10 parts of heavy curtain umbrella maple (HETEROPANAX FRAGRANS) leaf extract, punarnava
1 part of 0.1 part of (BOERHAVIA DIFFUSA) root extract, ascorbic acid methyl-monosilane alcohol pectate composition.
Embodiment 2
One kind going pouch lotion, includes the component of following mass percentage：The poly- front three of pouch composition 10%, the octyl of dispelling
Radical siloxane 5%, C30-45 alkyl dimethicones 1%, ring five dimethyl silicone polymer 1%, different tridecanol nutmeg
Acid esters 5%, tocopherol acetate 0.1%, Simulgel NS 0.1%, hydrolyzed wheat protein 0.5%, caffeine 0.01%,
PEG-35 lanolin 0.1%, carbomer 0.3%, asafoetide (FERULA ASSA FOETIDA) root extract 0.05%, arginine
PCA 0.3%, beta carotene 1%, glucose 1%, acrylamido copolymer 0.1%, gluconic acid sodium salt 0.1%, calcium gluconate
0.1%, calcium aspartate 0.01%, silica 0.5%, starch sodium octenyl succinate 0.05%, 1,3 butylene glycol 10%, 1,2-
Hexylene glycol 10%, sodium benzoate 0.7%, water surplus.
The pouch composition of dispelling is by 1 part of heavy curtain umbrella maple (HETEROPANAX FRAGRANS) leaf extract, punarnava
10 parts of 1 part of (BOERHAVIA DIFFUSA) root extract, ascorbic acid methyl-monosilane alcohol pectate compositions.
Embodiment 3
One kind going pouch lotion, includes the component of following mass percentage：The poly- front three of pouch composition 5%, the octyl of dispelling
Radical siloxane 3%, C30-45 alkyl dimethicones 3%, ring five dimethyl silicone polymer 2%, different tridecanol nutmeg
Acid esters 2%, tocopherol acetate 0.5%, Simulgel NS 0.3%, hydrolyzed wheat protein 0.3%, caffeine 0.05%,
PEG-35 lanolin 0.2%, carbomer 0.2%, asafoetide (FERULA ASSA FOETIDA) root extract 0.2%, arginine
PCA 0.2%, beta carotene 3%, glucose 0.5%, acrylamido copolymer 0.2%, gluconic acid sodium salt 0.05%, glucose
Sour calcium 0.05%, calcium aspartate 0.05%, silica 0.3%, starch sodium octenyl succinate 0.3%, sorbierite 10%, Xin Gan
Alcohol 5%, potassium sorbate 0.5%, water surplus.
The pouch composition of dispelling is by 5 parts of heavy curtain umbrella maple (HETEROPANAX FRAGRANS) leaf extract, punarnava
5 parts of 0.5 part of (BOERHAVIA DIFFUSA) root extract, ascorbic acid methyl-monosilane alcohol pectate compositions.
Embodiment 4
One kind going pouch lotion, includes the component of following mass percentage：The poly- front three of pouch composition 6%, the octyl of dispelling
Radical siloxane 2.5%, C30-45 alkyl dimethicones 2%, ring five dimethyl silicone polymer 1.5%, different tridecanol meat
Myristate 2%, tocopherol acetate 0.4%, Simulgel NS 0.4%, hydrolyzed wheat protein 0.2%, caffeine
0.05%, PEG-35 lanolin 0.2%, carbomer 0.2%, asafoetide (FERULA ASSA FOETIDA) root extract 0.2%,
Arginine PCA 0.2%, beta carotene 2.5%, glucose 0.6%, acrylamido copolymer 0.2%, gluconic acid sodium salt
0.05%, calcium gluconate 0.05%, calcium aspartate 0.04%, silica 0.3%, starch sodium octenyl succinate 0.25%, 1,
3-propanediol 5%, 1,3 butylene glycol 5%, sodium benzoate 0.3%, water surplus.
The pouch composition of dispelling is by 6 parts of heavy curtain umbrella maple (HETEROPANAX FRAGRANS) leaf extract, punarnava
0.5 part of (BOERHAVIA DIFFUSA) root extract, 4 parts of ascorbic acid methyl-monosilane alcohol pectate, millet starch
4 parts of 6 parts of (CAPSICUM FRUTESCENS) berry extract, butcher's broom (RUSCUS ACULEATUS) root extract compositions.
Embodiment 5
One kind going pouch lotion, includes the component of following mass percentage：The poly- front three of pouch composition 3%, the octyl of dispelling
Radical siloxane 2%, C30-45 alkyl dimethicones 4%, ring five dimethyl silicone polymer 1.5%, different tridecanol Pork and beans
Cool acid esters 4%, tocopherol acetate 0.2%, Simulgel NS 0.3%, hydrolyzed wheat protein 0.4%, caffeine 0.06%,
PEG-35 lanolin 0.2%, carbomer 0.15%, asafoetide (FERULA ASSA FOETIDA) root extract 0.1%, arginine
PCA 0.1-0.3%, beta carotene 2%, glucose 0.7%, acrylamido copolymer 0.15%, gluconic acid sodium salt 0.03%,
Calcium gluconate 0.02%, calcium aspartate 0.04%, silica 0.2%, starch sodium octenyl succinate 0.2%, 1,2- hexylene glycols
4%, sorbierite 4%, potassium sorbate 0.4%, water surplus.
The pouch composition of dispelling is by 7 parts of heavy curtain umbrella maple (HETEROPANAX FRAGRANS) leaf extract, punarnava
0.7 part of (BOERHAVIA DIFFUSA) root extract, 3 parts of ascorbic acid methyl-monosilane alcohol pectate, millet starch
10 parts of 0.1 part of (CAPSICUM FRUTESCENS) berry extract, butcher's broom (RUSCUS ACULEATUS) root extract compositions.
Embodiment 6
One kind going pouch lotion, includes the component of following mass percentage：The poly- front three of pouch composition 8%, the octyl of dispelling
Radical siloxane 4%, C30-45 alkyl dimethicones 2%, ring five dimethyl silicone polymer 2.5%, different tridecanol Pork and beans
Cool acid esters 2%, tocopherol acetate 0.8%, Simulgel NS 0.2%, hydrolyzed wheat protein 0.2%, caffeine 0.06%,
PEG-35 lanolin 0.2%, carbomer 0.25%, asafoetide (FERULA ASSA FOETIDA) root extract 0.15%, arginine
PCA 0.1-0.3%, beta carotene 4%, glucose 0.2%, acrylamido copolymer 0.25%, gluconic acid sodium salt 0.07%,
Calcium gluconate 0.08%, calcium aspartate 0.03%, silica 0.4%, starch sodium octenyl succinate 0.4%, sorbierite 18%,
Sodium benzoate 0.6%, water surplus.
The pouch composition of dispelling is by 2 parts of heavy curtain umbrella maple (HETEROPANAX FRAGRANS) leaf extract, punarnava
0.3 part of (BOERHAVIA DIFFUSA) root extract, 8 parts of ascorbic acid methyl-monosilane alcohol pectate, millet starch
0.1 part of 10 parts of (CAPSICUM FRUTESCENS) berry extract, butcher's broom (RUSCUS ACULEATUS) root extract composition.
Comparative example 1
The difference is that, comparative example 1 is not added with heavy curtain umbrella maple (HETEROPANAX FRAGRANS) leaf and carries with embodiment 3
Take object.
Comparative example 2
The difference is that, comparative example 2 is not added with the extraction of punarnava (BOERHAVIA DIFFUSA) root with embodiment 3
Object.
Comparative example 3
The difference is that, comparative example 3 is not added with ascorbic acid methyl-monosilane alcohol pectate with embodiment 3.
Comparative example 4
The difference is that, comparative example 4 is not added with millet starch (CAPSICUM FRUTESCENS) fruit and carries with embodiment 4
Take object.
Comparative example 5
The difference is that, comparative example 5 is not added with the extraction of butcher's broom (RUSCUS ACULEATUS) root with embodiment 4
Object.
Comparative example 6
The difference is that, pouch composition of dispelling in comparative example 6 is by heavy curtain umbrella maple (HETEROPANAX with embodiment 3
FRAGRANS) 11 parts of leaf extract, 0.09 part of punarnava (BOERHAVIA DIFFUSA) root extract, ascorbic acid methyl silicon
11 parts of compositions of alkanol pectate.
Comparative example 7
The difference is that, pouch composition of dispelling in comparative example 7 is by heavy curtain umbrella maple (HETEROPANAX with embodiment 3
FRAGRANS) 0.9 part of leaf extract, 1.1 parts of punarnava (BOERHAVIA DIFFUSA) root extract, ascorbic acid methyl silicon
0.9 part of composition of alkanol pectate.
Pouch lotion is gone to carry out clinical test by what embodiment 1-6, comparative example 1-7 were obtained, it is as a result as follows：
1, subject selects：Select the pouch patient in April, 2018~certain hospital accepts for medical treatment so far totally 1300, wherein male
Patient 400, female patient 900.
2, packet design：All patients are randomly divided into 13 groups, and each 100,13 groups of patients are at age, the state of an illness etc. without aobvious
Difference is write, is comparable.
3, application method：It is directly smeared, smears twice within one day, smear 7d altogether.
4, curative effect judging standard
It cures：Patient's pouch symptom disappears；
Effectively：Patient's pouch symptom gradually mitigates or symptom disappears；
In vain：Pouch symptom is without improvement；
Total effective rate=(curing number of cases+effective number of cases)/case load.
5, the results are shown in Table 1
Table 1
| Case load | Cure number of cases | Effective number of cases | Invalid number of cases | Total effective rate | |
| Embodiment 1 | 100 | 85 | 11 | 3 | 97% |
| Embodiment 2 | 100 | 85 | 10 | 5 | 95% |
| Embodiment 3 | 100 | 93 | 6 | 1 | 99% |
| Embodiment 4 | 100 | 97 | 3 | 0 | 100% |
| Embodiment 5 | 100 | 95 | 5 | 0 | 100% |
| Embodiment 6 | 100 | 96 | 4 | 0 | 100% |
| Comparative example 1 | 100 | 0 | 32 | 68 | 32% |
| Comparative example 2 | 100 | 0 | 25 | 75 | 25% |
| Comparative example 3 | 100 | 0 | 18 | 82 | 18% |
| Comparative example 4 | 100 | 85 | 9 | 6 | 94% |
| Comparative example 5 | 100 | 84 | 9 | 7 | 93% |
| Comparative example 6 | 100 | 0 | 45 | 10 | 45% |
| Comparative example 7 | 100 | 0 | 42 | 13 | 42% |
As shown in Table 1, the present invention goes pouch lotion to go pouch effect with excellent.
Comparative example 1-3 is with embodiment 1-3 comparisons as it can be seen that heavy curtain umbrella maple (HETEROPANAX FRAGRANS) leaf extract, Huang
Careful (BOERHAVIA DIFFUSA) root extract, ascorbic acid methyl-monosilane alcohol pectate are that pouch lotion removes pouch
Key component, and heavy curtain umbrella maple (HETEROPANAX FRAGRANS) leaf extract, punarnava (BOERHAVIA DIFFUSA) root
Extract, ascorbic acid methyl-monosilane alcohol pectate go the effect of pouch lotion just apparent when sharing, embody synergy
Effect.
Embodiment 4-6 is with embodiment 1-3 comparisons as it can be seen that millet starch (CAPSICUM FRUTESCENS) berry extract, phyllodium
The addition of tree (RUSCUS ACULEATUS) root extract significantly improves the effect for going pouch lotion to remove pouch；And it is right
Ratio 4-5 is with embodiment 4-6 comparisons as it can be seen that millet starch (CAPSICUM FRUTESCENS) berry extract, butcher's broom (RUSCUS
ACULEATUS promotion effect can be just embodied when) root extract shares, and have the function of synergy.
Comparative example 6-7 is with embodiment 1-3 comparisons as it can be seen that heavy curtain umbrella maple (HETEROPANAX FRAGRANS) leaf extract, Huang
Careful (BOERHAVIA DIFFUSA) root extract, ascorbic acid methyl-monosilane alcohol pectate only contain the present invention is specific
Go pouch effect just apparent in amount range.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore
All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (8)
- The pouch composition 1. a kind of silanol is dispelled, which is characterized in that include the component of following parts by weight：Heavy curtain umbrella maple 1-10 parts of (HETEROPANAX FRAGRANS) leaf extract, punarnava (BOERHAVIA DIFFUSA) root extract 0.1-1 Part, 1-10 parts of ascorbic acid methyl-monosilane alcohol pectate.
- 2. pouch composition according to claim 1 of dispelling, which is characterized in that the pouch composition of dispelling further includes as follows The component of parts by weight：0.1-10 parts of millet starch (CAPSICUM FRUTESCENS) berry extract, butcher's broom (RUSCUS ACULEATUS) root extract 0.1-10 parts.
- 3. the application of pouch composition in preparing cosmetics according to claim 1 or 2 of dispelling, wherein the pouch of dispelling The dosage of composition is the 0.1-10wt% of final products weight.
- 4. one kind going pouch lotion, which is characterized in that include the component of following mass percentage：As claimed in claim 1 or 2 Poly- trimethicone 1-5%, C30-45 alkyl dimethicone 1-5% of pouch composition 0.1-10%, octyl that dispels, Ring five dimethyl silicone polymer 1-3%, different tridecanol myristinate 0.1-5%, tocopherol acetate 0.1-1%, Simulgel NS0.1-0.5%, hydrolyzed wheat protein 0.1-0.5%, caffeine 0.01-0.1%, PEG-35 lanolin 0.1- 0.3%, carbomer 0.1-0.3%, asafoetide (FERULA ASSA FOETIDA) root extract 0.05-0.3%, arginine PCA0.1-0.3%, beta carotene 1-5%, glucose 0.1-1%, acrylamido copolymer 0.1-0.3%, gluconic acid sodium salt 0.01-0.1%, calcium gluconate 0.01-0.1%, calcium aspartate 0.01-0.1%, silica 0.05-0.5%, starch octenyl Sodium succinate 0.05-0.5%, polyalcohol 5-20%, water surplus.
- 5. according to claim 4 go pouch lotion, which is characterized in that the polyalcohol be glycerine, 1,3-PD, 1, At least one of 3- butanediols, 1,2- hexylene glycols, sorbierite, pungent glycol.
- 6. according to claim 4 go pouch lotion, which is characterized in that described to go pouch lotion further include preservative.
- 7. according to claim 6 go pouch lotion, which is characterized in that the preservative is potassium sorbate or benzoic acid Sodium.
- 8. according to claim 7 go pouch lotion, which is characterized in that the additive amount of the potassium sorbate is 0.3- The additive amount of 0.7wt%, the sodium benzoate are 0.3-0.7wt%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810455368.5A CN108379173A (en) | 2018-05-12 | 2018-05-12 | A kind of silanol is dispelled pouch composition and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810455368.5A CN108379173A (en) | 2018-05-12 | 2018-05-12 | A kind of silanol is dispelled pouch composition and application |
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| Publication Number | Publication Date |
|---|---|
| CN108379173A true CN108379173A (en) | 2018-08-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810455368.5A Withdrawn CN108379173A (en) | 2018-05-12 | 2018-05-12 | A kind of silanol is dispelled pouch composition and application |
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| Country | Link |
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| CN (1) | CN108379173A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112569139A (en) * | 2021-02-05 | 2021-03-30 | 东晟源研究院(广州)有限公司 | Soothing gel containing anti-inflammatory repairing composition and preparation method thereof |
| CN112807266A (en) * | 2020-12-30 | 2021-05-18 | 广州善草纪化妆品有限公司 | Plant composition, soap-based facial cleanser and preparation method and application thereof |
| CN113876671A (en) * | 2021-11-19 | 2022-01-04 | 广州兰蝶生物科技有限公司 | Anti-aging composition containing rape bud extract and preparation method thereof |
-
2018
- 2018-05-12 CN CN201810455368.5A patent/CN108379173A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112807266A (en) * | 2020-12-30 | 2021-05-18 | 广州善草纪化妆品有限公司 | Plant composition, soap-based facial cleanser and preparation method and application thereof |
| CN112569139A (en) * | 2021-02-05 | 2021-03-30 | 东晟源研究院(广州)有限公司 | Soothing gel containing anti-inflammatory repairing composition and preparation method thereof |
| CN113876671A (en) * | 2021-11-19 | 2022-01-04 | 广州兰蝶生物科技有限公司 | Anti-aging composition containing rape bud extract and preparation method thereof |
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Application publication date: 20180810 |