CN108379153A - The skin care compositions of Ji Yu Rou sprout capsule chain algae extracts and its application - Google Patents
The skin care compositions of Ji Yu Rou sprout capsule chain algae extracts and its application Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A61Q19/00—Preparations for care of the skin
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Abstract
The present invention relates to a kind of skin care compositions of Ji Yu Rou sprout capsule chain algae extracts and its applications.The skin care compositions of the Ji Yu Rou sprout capsule chain algae extracts, including active component, the active component includes 1 part~3 Fen Rou sprout capsule chains algae extracts, 0.5 part~1 part of hundred golden flower extracts, 0.5 part~1 part of chrysanthemum coccineum flower extract, 0.1 part~0.5 part of Cortex Phellodendri extract and 0.1 part~0.5 part of hamamelis extract based on mass fraction.The skin care compositions of above-mentioned Ji Yu Rou sprouts capsule chain algae extract is safe, applicability is wide and anti-acne effect is notable.
Description
Technical field
The present invention relates to daily chemical product technical field, the skin care compositions for capsule chain algae extract of clearing the fields of weeds more particularly to Ji Yu Rou
And its application.
Background technology
Acne is also known as acne or whelk, is a kind of chronic inflammatory skin of pilosebaceous follicle, main hair in cheek,
The vigorous place of the sebaceous glands such as forehead and back, the pleomorphism skin lesion such as clinical manifestation acne, papule, warts, tubercle.Seriously
Acne may form permanent scar, seriously affect beauty.Hypersteatosis, pilosebaceous duct blocking, bacterium sense
The factors such as dye and inflammatory reaction can induce acne.
Currently, the method for anti-acne is broadly divided into two kinds of " for oral administration " and " external application ", " for oral administration " is primarily referred to as taking antibiotic orally, use
Hormone regulating endocrine and dietetic regulation etc., being capable of a degree of alleviation acne." external application " is mainly by smearing anti-acne production
Product are to achieve the effect that anti-acne, but existing product for resolving poxes is mostly larger containing irritations such as hormone, antibiotic or vitamin A acids
Component, the acne caused to bacterium infection dispel drug resistance with obvious effects, but easily causing skin, and safety is poor, together
When existing product for resolving poxes spininess it is poor to acne, applicability caused by single bacterium.
Invention content
Based on this, it is necessary to which offer one kind is safe, applicability is wide and the significant Ji Yu Rou sprouts capsule chain algae of anti-acne effect
The skin care compositions of extract and its application.
A kind of skin care compositions of Ji Yu Rou sprouts capsule chain algae extract, including active component, the active component is with quality
Score meter includes 1 part~3 Fen Rou sprout capsule chain algae extracts, 0.5 part~1 part of hundred golden flower extracts, 0.5 part~1 part red
Flower pyrethrum flowers extract, 0.1 part~0.5 part of Cortex Phellodendri extract and 0.1 part~0.5 part of hamamelis extract.
The skin care compositions Tong Guo of above-mentioned Ji Yu Rou sprout capsule chain algae extract clear the fields of weeds Rou capsule chain algae extract and other plant
Property component synergistic effect, can not only make above-mentioned skin care compositions have stronger antibacterial anti-inflammatory effect, additionally it is possible to above-mentioned shield
Skin component object can quickly play anti-acne effect, while above-mentioned skin care compositions can also keep the grease of skin improvement skin
Balance keeps skin water profit, high resilience.Experiment proves that the skin care compositions Zhong Rou sprouts of Shang Shu Rou sprouts capsule chain algae extract
Capsule chain algae extract acts synergistically with other components, especially acts synergistically with Cortex Phellodendri extract, can inhibit golden yellow
The activity of staphylococcus and propionibacterium acnes, can effectively improve and removing acne, quick, in addition, above-mentioned activearm
It is vegetalitas component to divide, safety, nonirritant.The safety of the skin care compositions of above-mentioned Ji Yu Rou sprouts capsule chain algae extract
Height, applicability is wide and anti-acne effect is notable.
The active component further includes 0.1 part~2 parts of kardiseed based on mass fraction in one of the embodiments,
Oil.
The active component includes 1.5 parts~2.5 Fen Rou sprout capsule chains based on mass fraction in one of the embodiments,
Algae extract, 0.6 part~0.8 part of hundred golden flower extracts, 0.6 part~0.8 part of chrysanthemum coccineum flower extract, 0.2 part~
0.4 part of Cortex Phellodendri extract, 0.2 part~0.4 part of hamamelis extract and 0.5 part~1.5 parts of safflower seed oil.
In one of the embodiments, the active component further include based on mass fraction 0.5 part~1 part pollen and
0.05 part~0.1 part of allantoin.
The active component further includes 0.1 part~1 part of oligopeptides -5 based on mass fraction in one of the embodiments,.
Further include moisturizer, thickener and solvent in one of the embodiments, the active component, the moisturizer,
The mass ratio of the thickener and the solvent is " 4~9 ":" 2.5~16 ":" 0.2~2 ":" 70~91 ".
In one of the embodiments, the moisturizer based on mass fraction include 2 parts~10 parts glycerine, 2 parts~5 parts
1,3 butylene glycol and 0.5 part~1 part of mannitol.
In one of the embodiments, the thickener in terms of mass fraction including 0.1 part~0.8 part of carbomer and
0.1 part~1.2 parts of hydroxyethyl cellulose.
The solvent is selected from least one of distilled water and deionized water in one of the embodiments,.
Skin care compositions the answering in skin care item of above-described embodiment any one of them Ji Yu Rou sprout capsule chain algae extracts
With.
Specific implementation mode
It to facilitate the understanding of the present invention, below will be to invention is more fully described.Give the preferable of the present invention
Embodiment.But the present invention can realize in many different forms, however it is not limited to embodiment described herein.Phase
Instead, purpose of providing these embodiments is makes the disclosure of the present invention more thorough and comprehensive.
Unless otherwise defined, all of technologies and scientific terms used here by the article and belong to the technical field of the present invention
The normally understood meaning of technical staff is identical.Used term is intended merely to description tool in the description of the invention herein
The purpose of the embodiment of body, it is not intended that in the limitation present invention.
The skin care compositions of the Ji Yu Rou sprout capsule chain algae extract of one embodiment, including active component, active component with
Mass fraction meter include 1 part~3 Fen Rou sprout capsule chain algae extracts, 0.5 part~1 part of hundred golden flower extracts, 0.5 part~1 part
Chrysanthemum coccineum flower extract, 0.1 part~0.5 part of Cortex Phellodendri extract and 0.1 part~0.5 part witch hazel extraction
Object.
Rou clears the fields of weeds capsule chain Trentepohlia in brown alga, and main active substances are seeweed polyphenol and algal polysaccharides, and seeweed polyphenol has antioxygen
Change, antibacterial, antiviral activity can inhibit the activity of hyaluronidase, and algal polysaccharides are to Escherichia coli, staphylococcus aureus
Etc. all having inhibiting effect, has the function of antibacterial anti-inflammatory, while also there is algal polysaccharides certain inoxidizability , Rou to clear the fields of weeds capsule chain
Algae also contains Sargassum protein and various vitamins, skin can be made to keep water profit to skin extra-nutrition substance and moisture, rich
Elasticity.
In a wherein embodiment, active component is in terms of mass fraction including 1.5 parts~2.5 parts of Rou sprout capsule chain algaes
Extract., Rou sprouts capsule chain algae extract is 1 part, 1.5 parts, 2 parts, 2.5 parts or 3 parts in some embodiments.
In a wherein embodiment, Rou sprout capsule chain algae extracts are the alcohol extract of Rou sprout capsule chain algaes.One wherein
The preparation method of embodiment Zhong , Rou sprout capsule chain algae extract is：Jiang the drying of Rou sprout capsule chain algaes, it is ground into coarse powder, volume is added
Percentage composition is the aqueous solution of 85%~95% ethyl alcohol, in ultrasonic frequency 25kHz~35kHz, 300W~400W, 45 DEG C~65
DEG C extraction 40 minutes~100 minutes, separation of solid and liquid obtain extracting solution, after drying, get Dao Rou clear the fields of weeds capsule chain algae extract, wherein
It is 1 to crush Hou Rou sprout capsule chain algaes and the mass ratio for the aqueous solution that volumn concentration is 85%~95% ethyl alcohol:10~1:20,
Dry mode is drying or spray drying.Certainly, it should be noted that , Rou sprout capsule chain algae extracts may be commercially available.
Contain chlorogenic acid in hundred golden flower extracts, chlorogenic acid has inhibition to make Gram-negative bacteria, gram-positive bacteria
With also with definitely antiviral effect, and chlorogenic acid has stronger inoxidizability, can remove hydroxyl radical free radical and super oxygen
The free radicals such as radical anion, hundred golden flower extracts also contain gentiamarin, have the function of that anti-inflammatory is releived.One wherein
In embodiment, in terms of mass fraction, hundred golden flower extracts can also be 0.6 part~0.8 part.In some embodiments, hundred gold medal
Flower extract can be 0.5 part, 0.6 part, 0.7 part, 0.8 part, 0.9 part or 1 part.
In a wherein embodiment, hundred golden flower extracts are the alcohol extract of hundred golden flower.An embodiment wherein
In, the preparation method of hundred golden flower extracts：Hundred golden flower are dried, the water for the ethyl alcohol that volumn concentration is 50%~75% is added
Solution extracts 40 minutes~80 minutes in 40 DEG C~50 DEG C, and separation of solid and liquid obtains extracting solution, after drying, obtains hundred golden flower extractions
Object, wherein the aqueous solution for the ethyl alcohol that the quality of hundred golden flower after dry and the volumn concentration of addition are 50%~75%
The ratio between volume is 1:20~1:30, dry mode is vacuum drying or rotary evaporation drying.Certainly, it should be noted that hundred
Golden flower extracts may be commercially available.
Chrysanthemum coccineum flower extract triterpene compound with anti-inflammatory effect containing there are many, to the inductivity mistake of skin
It is quick to have inhibiting effect, dermatitis can be treated, additionally it is possible to enhance the resistance of capillary, inhibit capillary permeability, can disappear
Except free radical, has the function of anti-oxidant and alleviate aging, simultaneously, additionally it is possible to inhibit melanocyte to a certain extent, have
The effect of certain whitening spot-removing.In a wherein embodiment, chrysanthemum coccineum flower extract is 0.6 part~0.8 part.
In some embodiments, chrysanthemum coccineum flower extract is 0.5 part, 0.6 part, 0.7 part, 0.8 part, 0.9 part or 1 part.
In a wherein embodiment, chrysanthemum coccineum flower extract is the water extract of chrysanthemum coccineum flower.Wherein
In one embodiment, the preparation method of chrysanthemum coccineum flower extract：Chrysanthemum coccineum is spent into drying, pure water is added in 80 DEG C
~100 DEG C of extraction 30min~60min, separation of solid and liquid obtain extracting solution, after drying, obtain chrysanthemum coccineum flower extract,
In, the quality of the chrysanthemum coccineum flower after crushing and the ratio between the volume of pure water of addition are 1:20~1:50, dry mode is
Vacuum drying or spray drying.Certainly, it should be noted that chrysanthemum coccineum flower extract may be commercially available.
Cortex Phellodendri extract contains a variety of alkaloids such as jamaicin and phellodendrine, equal to a variety of Grain-positives and negative bacterium
Have bacteriostasis, it is especially more apparent to the antibacterial action of staphylococcus aureus, skin can be prevented because of microorganism infection
And inflammation, there is preferably anti-inflammatory effect, meanwhile, jamaicin can remove a variety of free radicals, have stronger antioxidant activity.
In a wherein embodiment, in terms of mass fraction, Cortex Phellodendri extract can be 0.2 part~0.4 part.In some implementations
In example, Cortex Phellodendri extract is 0.1 part, 0.2 part, 0.3 part, 0.4 part or 0.5 part.
In a wherein embodiment, Cortex Phellodendri extract is the alcohol extract of Cortex Phellodendri.An implementation wherein
In mode, the preparation method of Cortex Phellodendri extract：By Cortex Phellodendri drying, it is ground into coarse powder, volumn concentration, which is added, is
The aqueous solution of 50%~70% ethyl alcohol extracts 30 minutes~60 minutes in 50 DEG C~60 DEG C, and separation of solid and liquid obtains extracting solution, passes through
After drying, Cortex Phellodendri extract is obtained, wherein the quality of Cortex Phellodendri and the volumn concentration of addition after dry are
The ratio between 50%~70% volume of aqueous solution of ethyl alcohol is 1:10~1:15, dry mode is vacuum drying or rotary evaporation
It is dry.Certainly, it should be noted that Cortex Phellodendri extract may be commercially available.
Hamamelis extract can adjust sebum secretion, promote lymph blood circulation, have releive, restrain, the effect of antibacterial
Fruit, can activating cell aromatizing enzyme and cathepsin it is horizontal to improve cortex local estrogen, enhancing Skin Cell is newly old
Metabolism has the function of anti-aging, maintenance skin elasticity and crease-resistant.In a wherein embodiment, hamamelis extract is
Hamamelis extract.In a wherein embodiment, hamamelis extract is solid extract.An implementation wherein
In mode, in terms of mass fraction, hamamelis extract be include 0.2 part~0.4 part.In some embodiments, witch hazel is extracted
Object is 0.1 part, 0.2 part, 0.3 part, 0.4 part or 0.5 part.
In a wherein embodiment, active component further includes 0.1 part~2 parts of safflower seed oil in terms of mass fraction.
Safflower seed oil contains linolenic acid, vitamin E and vitamin A etc., can improve pachylosis, so that skin is become water tender smooth,
And skin metabolism can be promoted, be conducive to the absorption to other components in skin care compositions, meanwhile, safflower seed oil has steady
Fixed fragrance reduces stimulation of the essence addition to skin without additional addition essence.Further, in terms of mass fraction, safflower
Seed oil can be 0.5 part~1.5 parts.In some embodiments, in terms of mass fraction, safflower seed oil can be 0.1 part, 0.5 part,
1 part, 1.5 parts or 2 parts.
In a wherein embodiment, the preparation method of safflower seed oil is：By kardiseed drying, it is ground into coarse powder, it will
Kardiseed after crushing is added in extraction kettle, uses supercritical CO2It is to extract under 25MPa~30MPa in 25 DEG C~25 DEG C, extracting pressure
2h~5h is taken to obtain, CO2Flow be 1kg/h~4kg/h.
In a wherein embodiment, active component is in terms of mass fraction including 1.5 parts~2.5 parts of Rou sprout capsule chain algaes
Extract, 0.6 part~0.8 part of hundred golden flower extracts, 0.6 part~0.8 part of chrysanthemum coccineum flower extract, 0.2 part~0.4
The Cortex Phellodendri extract, 0.2 part~0.4 part of hamamelis extract and 0.5 part~1.5 parts of safflower seed oil of part.Above-mentioned work
Property component each substance synergistic effect, there is preferable anti-inflammatory anti-acne effect.
In a wherein embodiment, active component further includes 0.5 part~1 part of pollen and 0.05 in terms of mass fraction
Part~0.1 part of allantoin.Rich in ingredients such as a variety of amino acid, vitamin, trace element and phosphatide in pollen, skin can be enhanced
Skin resistance improves moisture of skin, promotes Skin Cell reparation.Allantoin can reduce the adhesion strength of corneocyte, accelerometer
Chrotoplast updates.The addition of pollen and allantoin acts synergistically with other components in active component, can accelerate dispelling for acne.
In a wherein embodiment, pollen is honeysuckle powder.In some embodiments, pollen is 0.6 part~0.8 part, allantois
Element is 0.06 part~0.08 part.
In a wherein embodiment, active component further includes 0.1 part~1 part of oligopeptides -5 in terms of mass fraction.It is few
Peptide -5 is small-molecular peptides, directly can effectively be absorbed by cell, rapid replenishing collagen, to promote skin metabolism, stimulation
Cytothesis and proliferation, meanwhile, the addition of oligopeptides -5 can promote absorption of the skin to the nutriment in other components, can
It transports various trace elements and enters cell.In a wherein embodiment, oligopeptides -5 is 0.4 part~8 parts.In some embodiment party
In formula, oligopeptides -5 is 0.1 part, 0.2 part, 0.3 part, 0.4 part, 0.5 part, 0.6 part, 0.7 part, 0.8 part, 0.9 part or 1 part.
In a wherein embodiment, active component includes 1 part~3 parts of Rou sprout capsule chain algae extractions based on mass fraction
Object, 0.5 part~1 part of hundred golden flower extracts, 0.5 part~1 part of chrysanthemum coccineum flower extract, 0.1 part~0.5 part of cork tree
Bark extract, 0.1 part~0.5 part of hamamelis extract, 0.1 part~2 parts of safflower seed oil, 0.5 part~1 part of pollen,
0.05 part~0.1 part of allantoin and 0.1 part~1 part of oligopeptides -5.Above-mentioned active component Zhong Yi Rou sprout capsule chain algae extract is
Primary raw material acts synergistically with other components, and various nutriments can be rapidly absorbed, and has the work of preferable anti-inflammatory anti-acne
With, additionally it is possible to mitigate microgroove, makes skin high resilience.
In a wherein embodiment, base further includes moisturizer, increases in the skin care compositions of Rou sprout capsule chain algae extracts
Thick dose and solvent, and active component, moisturizer, thickener and solvent mass ratio be 4~9:2.5~16:0.2~2:70~
91.Moisturizer can moisturizing, improve skin microcirculation, be conducive to absorption of the skin to active component, thickener and solvent
Addition to above-mentioned skin care compositions excipient, in order to the use of skin care compositions.In a wherein embodiment, activearm
Point, the mass ratio of moisturizer, thickener and solvent be 6:11:1:80.
In a wherein embodiment, moisturizer include based on mass fraction 2 parts~10 parts glycerine, 2 parts~5 parts
1,3 butylene glycol and 0.5 part~1 part of mannitol.Glycerine, 1,2- pentanediols and mannitol all have stronger moisture absorption and make
With, the water of skin can be kept to moisten, the hydroxyl in mannitol can be combined with water in the form of hydrogen bond, have certain water lock
Moisture-keeping efficacy can be such that skin persistently moistens.Further, moisturizer based on mass fraction include 3 parts~7 parts glycerine, 3 parts
~4 parts of 1,3 butylene glycol and 0.6 part~0.8 part of mannitol.Further, moisturizer includes 5 based on mass fraction
The glycerine, 4 parts of 1,3 butylene glycol and 0.7 part of mannitol of part.
In a wherein embodiment, thickener includes 0.1 part~0.8 part of carbomer and 0.1 in terms of mass fraction
Part~1.2 parts of hydroxyethyl cellulose.Carbomer and ethoxy can increase the viscosity of skin care compositions, additionally it is possible to stablize and live
Acne-removing inflammation-diminishing ingredient in property component.Further, thickener in terms of mass fraction including 0.3 part~0.6 part of carbomer and
0.5 part~0.9 part of hydroxyethyl cellulose.
In a wherein embodiment, solvent is at least one of distilled water and deionized water.Certainly, it needs to illustrate
, solvent is not limited to above-mentioned point out that substance, solvent may be fruit juice, such as cider.
In a wherein embodiment, base is wrapped in the skin care compositions of Rou sprout capsule chain algae extracts in terms of mass fraction
Include 1 part~3 Fen Rou sprout capsule chains algae extracts, 0.5 part~1 part of hundred golden flower extracts, 0.5 part~1 part of chrysanthemum coccineum
Flower extract, 0.1 part~0.5 part of Cortex Phellodendri extract, 0.1 part~0.5 part of hamamelis extract, 0.1 part~2 parts
Safflower seed oil, 0.5 part~1 part of pollen, 0.05 part~0.1 part of allantoin, 0.1 part~1 part of oligopeptides -5,2 parts~10 parts
Glycerine, 2 parts~5 parts of 1,3 butylene glycol, 0.5 part~1 part of mannitol, 0.1 part~0.8 part of carbomer and 0.1 part
~1.2 parts of hydroxyethyl cellulose.The skin care compositions is gel, facial mask or face cream can be used as to use.
In a wherein embodiment, in terms of mass fraction, base in Rou clear the fields of weeds capsule chain algae extract skin care compositions also
Include 0.05 part~0.3 part of renovation agent.Further, in terms of mass fraction, the skin care group of Ji Yu Rou sprout capsule chain algae extracts
Close the renovation agent that object further includes 0.1 part~0.2 part.In some embodiments, renovation agent is 0.05 part, 0.1 part, 0.2 part or 0.3
Part.
Renovation agent is selected from least one of epithelical cell growth factor, stem cell factor and vascular endothelial growth factor.
In a wherein embodiment, in terms of mass fraction, renovation agent includes 0.05 part~0.3 part of epithelical cell growth factor.
Further, in terms of mass fraction, renovation agent includes 0.1 part~0.2 part of epithelical cell growth factor.In some embodiments
In, epithelical cell growth factor is 0.05 part, 0.1 part, 0.2 part or 0.3 part.Epithelical cell growth factor being capable of inducing cell increasing
It grows, Differentiation, promotes body epidermal cell, epithelial cell, fibroblastic growth, division and metabolism, promote micro-
The growth of blood vessel improves the microenvironment of cell growth, can repair Local Damaged skin, improves the pigment situation of skin, adjusts
Collagenous fibres, enhance skin elasticity, reduces wrinkle of skin and prevent the effect of skin aging.Granulation tissue can also be stimulated
The epithelialization for forming and promoting granulation tissue is prevented and is protected to shorten the wound healing time and reduce the effect of scar formation
Manage sore of fullying recover from an illness.
In a wherein embodiment, in terms of mass fraction, renovation agent include 0.05 part~0.3 part stem cell because
Son.Further, in terms of mass fraction, renovation agent includes 0.1 part~0.2 part of stem cell factor.In some embodiments, it does
Cell factor is 0.05 part, 0.1 part, 0.2 part or 0.3 part.Stem cell factor is also known as mast cell growth factor, Kit ligands
(KL) or the Steel factors (SLF), it is a kind of acidoglycoprotein generated by the stroma cell in bone marrow microenvironment.Stem cell because
Son can repair tissue cell, promote the metabolism of skin, improve the microcirculation of skin, prevent and modification skin aging.
In a wherein embodiment, in terms of mass fraction, renovation agent includes 0.05 part~0.3 part of blood vessel endothelium life
The long factor.Further, in terms of mass fraction, renovation agent includes 0.1 part~0.2 part of vascular endothelial growth factor.At some
In embodiment, vascular endothelial growth factor is 0.05 part, 0.1 part, 0.2 part or 0.3 part.Vascular endothelial growth factor can have
Effect improves local vascular permeability, can provide sufficient nutriment and its for the synthesis of fibroblastic proliferation and collagen
His growth factor promotes division, the proliferation of cell, improves skin microcirculation, while can also effectively facilitate new capillary vessel
Generation, improve the metabolism of skin, play the role of anti-aging.
In a wherein embodiment, in terms of mass fraction, renovation agent includes 0.03 part~0.1 part of epidermal cell life
The long factor, 0.01 part~0.1 part of stem cell factor, 0.01 part~0.1 part of vascular endothelial growth factor.
The skin care compositions Tong Guo of above-mentioned Ji Yu Rou sprout capsule chain algae extract clear the fields of weeds Rou capsule chain algae extract and other plant
Property component synergistic effect, can not only make above-mentioned skin care compositions have stronger antibacterial anti-inflammatory effect, additionally it is possible to above-mentioned shield
Skin component object can quickly play anti-acne effect, while above-mentioned skin care compositions can also keep the grease of skin improvement skin
Balance keeps skin water profit, high resilience.Experiment proves that the skin care compositions Zhong Rou sprouts of Shang Shu Rou sprouts capsule chain algae extract
Capsule chain algae extract acts synergistically with other components, especially acts synergistically with Cortex Phellodendri extract, can inhibit golden yellow
The activity of staphylococcus and propionibacterium acnes, can effectively improve and removing acne, quick, in addition, above-mentioned activearm
It is vegetalitas component to divide, safety, nonirritant.The safety of the skin care compositions of above-mentioned Ji Yu Rou sprouts capsule chain algae extract
Height, applicability is wide and anti-acne effect is notable.
In a wherein embodiment, above-mentioned base is in skin care compositions the answering in facial mask of Rou sprout capsule chain algae extracts
With.
In wherein some embodiments, above-mentioned facial mask further includes the acceptable auxiliary material of skin care item.
In wherein some embodiments, the acceptable auxiliary material of skin care item is in pH adjusting agent, essence and chelating agent
It is at least one.
PH adjusting agent can be such that the pH of above-mentioned facial mask adjusts to 6~7.PH adjusting agent is in triethanolamine and potassium hydroxide
It is at least one.In a wherein embodiment, pH adjusting agent includes 0.01 part~0.03 part of hydroxide based on mass fraction
Potassium and 0.05 part~0.1 part of triethanolamine.Certainly, it should be noted that if the pH of above-mentioned facial mask is 6~7, pH adjusting agent
It can be omitted.
In a wherein embodiment, in terms of mass fraction, above-mentioned skin care item further include 0.1 part~0.3 part of chelating
Agent, chelating agent are selected from least one of disodium ethylene diamine tetraacetate and sodium versenate.In some embodiments, chela
Mixture is 0.1 part, 0.2 part or 0.3 part.
In addition, the preparation method for the facial mask of capsule chain algae extract of clearing the fields of weeds the present invention also provides the Ji Yu Rou of the above embodiment,
Include the following steps：
S110, solvent is stirred be heated to temperature be 75 DEG C~80 DEG C.
S120, it maintains the temperature at 75 DEG C~80 DEG C, thickener is added into solvent and stirs evenly.
In a wherein embodiment, agitating mode is mechanical agitation, and the rate of stirring is 400rpm~800rpm, is stirred
Mix the time 15 minutes~25 minutes.
S130,50 DEG C~60 DEG C are cooled to and keeps, continuously add moisturizer and is stirred until homogeneous.
In a wherein embodiment, agitating mode is mechanical agitation, and the rate of stirring is 400rpm~800rpm, is stirred
Mix the time 10 minutes~20 minutes.
S140,40 DEG C~45 DEG C are cooled to and is kept, continuously added active component and chelating agent, be stirred until homogeneous.
S150, the pH value for continuously adding pH adjusting agent adjusting mixture are 6~7.
The facial mask preparation method of above-mentioned Ji Yu Rou sprouts capsule chain algae extract is simple, easily realizes industrialized production.
Here is the explanation of specific embodiment, and following embodiment unless otherwise specified, is not then contained except inevitably miscellaneous
The component pointed out is not known in other other than matter.
In following embodiment, Rou sprout capsule chain algaes are such as ground into coarse powder without specified otherwise , Rou sprout capsule chain algae extract Wei, are added
Enter the aqueous solution that volumn concentration is 90% ethyl alcohol, is extracted 60 minutes in ultrasonic frequency 30kHz, 350W, 555 DEG C, solid-liquid
Isolated extracting solution simultaneously obtains after drying, and crushes Hou Rou sprout capsule chain algaes and aqueous solution that volumn concentration is 90% ethyl alcohol
Mass ratio be 1:The water content of 15 , Rou sprout capsule chain algae extracts is 5wt%.Hundred golden flower extracts are to dry hundred golden flower, are added
The aqueous solution for entering the ethyl alcohol that volumn concentration is 60% extracts 60 minutes in 45 DEG C, and separation of solid and liquid obtains extracting solution after drying
It obtains, the quality of hundred golden flower and the volumn concentration of addition after drying are that the ratio between 60% volume of aqueous solution of ethyl alcohol is
1:25, the water content of hundred golden flower extracts is 6wt%.
In following embodiment, unless otherwise specified, chrysanthemum coccineum flower extract is that chrysanthemum coccineum is spent drying, is heated
Pure water extracts 45min in 90 DEG C, and separation of solid and liquid obtains extracting solution and obtained after drying, the quality of the chrysanthemum coccineum flower after drying
It is 1 with the ratio between the volume of pure water of addition:35, the water content of chrysanthemum coccineum flower extract is 5wt%.Cortex Phellodendri extract
For Cortex Phellodendri is dry, be ground into coarse powder, the aqueous solution for the ethyl alcohol that volumn concentration is 50%~70% is added in 50 DEG C
~60 DEG C are extracted 30 minutes~60 minutes, and separation of solid and liquid obtains extracting solution and obtains after drying, the matter of the Cortex Phellodendri after drying
It is 1 that amount, which is the ratio between 50%~70% volume of aqueous solution of ethyl alcohol with the volumn concentration being added,:10, Cortex Phellodendri extraction
The water content of object is 5wt%.Safflower seed oil is that kardiseed is dry, is ground into coarse powder, and extraction is added in the kardiseed after crushing
In kettle, supercritical CO is used2It is to extract 3 hours to obtain under 28MPa in 30 DEG C, extracting pressure, CO2Flow be 3kg/h.
In following embodiment, unless otherwise specified, hamamelis extract is purchased from Xi'an Qing Zhi Bioisystech Co., Ltd, red
Flower seed oil is purchased from.Honeysuckle pollen is purchased from Shaanxi Sen Fu natural products Co., Ltd.Propionibacterium acnes reference culture
ATCC11827, staphylococcus aureus reference culture ATCC100817 are provided by Guangdong Culture Collection.Beef
Cream culture medium is purchased from OXOID companies with brain-heart infusion medium.
Embodiment 1
The skin care compositions of the present embodiment includes 1 Fen Rou sprout capsule chains algae extract, the hundred of 0.5 part according to the mass fraction
Golden flower extracts, 0.5 part of chrysanthemum coccineum flower extract, 0.1 part of Cortex Phellodendri extract and the extraction of 0.1 part of witch hazel
Object.
Embodiment 2
The skin care compositions of the present embodiment includes 3 Fen Rou sprout capsule chains algae extracts, 1 part of hundred gold medals according to the mass fraction
Flower extract, 1 part of chrysanthemum coccineum flower extract, 0.5 part of Cortex Phellodendri extract and 0.5 part of hamamelis extract.
Embodiment 3
The skin care compositions of the present embodiment includes 1 Fen Rou sprout capsule chains algae extract, the hundred of 0.5 part according to the mass fraction
Golden flower extracts, 0.5 part of chrysanthemum coccineum flower extract, 0.1 part of Cortex Phellodendri extract, the extraction of 0.1 part of witch hazel
Object and 0.1 part of safflower seed oil.
Embodiment 4
The skin care compositions of the present embodiment is carried including 1 part of Chinese rhubarb extract, 0.5 part of hundred golden flower according to the mass fraction
Take object, 0.5 part of chrysanthemum coccineum flower extract, 0.1 part of Cortex Phellodendri extract and 0.1 part of hamamelis extract.
Embodiment 5
The skin care compositions of the present embodiment includes 1 Fen Rou sprout capsule chains algae extract, the hundred of 0.5 part according to the mass fraction
Golden flower extracts, 0.5 part of chrysanthemum coccineum flower extract, 0.1 part of Chinese rhubarb extract and 0.1 part of hamamelis extract.
Embodiment 6
The skin care compositions of the present embodiment includes 1 Fen Rou sprout capsule chains algae extract, the hundred of 0.5 part according to the mass fraction
Golden flower extracts, 0.5 part of chrysanthemum coccineum flower extract, 0.1 part of Cortex Phellodendri extract, the extraction of 0.1 part of witch hazel
Object, 2 parts of glycerine, 2 parts of 1,3 butylene glycol, 0.5 part of mannitol, 0.1 part of carbomer, 0.1 part of hydroxy ethyl fiber
Element, 91 parts of distilled water, 0.1 part of sodium versenate, 0.01 part of potassium hydroxide and 0.05 part of triethanolamine.
Embodiment 7
The skin care compositions of the present embodiment includes 1 Fen Rou sprout capsule chains algae extract, the hundred of 0.5 part according to the mass fraction
Golden flower extracts, 0.5 part of chrysanthemum coccineum flower extract, 0.1 part of Cortex Phellodendri extract, the extraction of 0.1 part of witch hazel
Object, 0.1 part of safflower seed oil, 2 parts of glycerine, 2 parts of 1,3 butylene glycol, 0.5 part of mannitol, 0.1 part of carbomer,
0.1 part of hydroxyethyl cellulose, 91 parts of distilled water, 0.1 part of sodium versenate, 0.01 part of potassium hydroxide and
0.05 part of triethanolamine.
Embodiment 8
The skin care compositions of the present embodiment is carried including 1 part of Chinese rhubarb extract, 0.5 part of hundred golden flower according to the mass fraction
Take object, 0.5 part of chrysanthemum coccineum flower extract, 0.1 part of Cortex Phellodendri extract, 0.1 part of hamamelis extract, 2 parts
Glycerine, 2 parts of 1,3 butylene glycol, 0.5 part of mannitol, 0.1 part of carbomer, 0.1 part of hydroxyethyl cellulose, 91 parts
Distilled water, 0.1 part of sodium versenate, 0.01 part of potassium hydroxide and 0.05 part of triethanolamine.
Embodiment 9
The skin care compositions of the present embodiment includes 1 Fen Rou sprout capsule chains algae extract, the hundred of 0.5 part according to the mass fraction
Golden flower extracts, 0.5 part of chrysanthemum coccineum flower extract, 0.1 part of Chinese rhubarb extract, 0.1 part of hamamelis extract, 2
Part glycerine, 2 parts of 1,3 butylene glycol, 0.5 part of mannitol, 0.1 part of carbomer, 0.1 part of hydroxyethyl cellulose, 91
The distilled water, 0.1 part of sodium versenate, 0.01 part of potassium hydroxide and 0.05 part of triethanolamine of part.
Embodiment 10
The skin care compositions of the present embodiment includes 1 Fen Rou sprout capsule chains algae extract, the hundred of 0.5 part according to the mass fraction
Golden flower extracts, 0.5 part of chrysanthemum coccineum flower extract, 0.1 part of Cortex Phellodendri extract, the extraction of 0.1 part of witch hazel
Object, 0.1 part of safflower seed oil, 0.5 part of pollen, 0.05 part of allantoin, 2 parts of glycerine, 2 parts of 1,3 butylene glycol, 0.5 part
Mannitol, 0.1 part of carbomer, 0.1 part of hydroxyethyl cellulose, 91 parts of distilled water, 0.1 part of ethylenediamine tetra-acetic acid
Trisodium, 0.01 part of potassium hydroxide and 0.05 part of triethanolamine.
Embodiment 11
The skin care compositions of the present embodiment includes 1 Fen Rou sprout capsule chains algae extract, the hundred of 0.5 part according to the mass fraction
Golden flower extracts, 0.5 part of chrysanthemum coccineum flower extract, 0.1 part of Cortex Phellodendri extract, the extraction of 0.1 part of witch hazel
Object, 0.1 part of safflower seed oil, 0.5 part of pollen, 0.05 part of allantoin, 0.1 part of oligopeptides -5,2 parts of glycerine, the 1 of 2 parts,
3- butanediols, 0.5 part of mannitol, 0.1 part of carbomer, 0.1 part of hydroxyethyl cellulose, 91 parts of distilled water, 0.1 part
Sodium versenate, 0.01 part of potassium hydroxide and 0.05 part of triethanolamine.
Embodiment 12
The skin care compositions of the present embodiment includes 1 Fen Rou sprout capsule chains algae extract, the hundred of 0.5 part according to the mass fraction
Golden flower extracts, 0.5 part of chrysanthemum coccineum flower extract, 0.1 part of Cortex Phellodendri extract, the extraction of 0.1 part of witch hazel
Object, 2 parts of glycerine, 2 parts of 1,3 butylene glycol, 0.5 part of mannitol, 0.1 part of carbomer, 0.1 part of hydroxy ethyl fiber
Element, 91 parts of distilled water, 0.05 part of stem cell factor, 0.1 part of sodium versenate, 0.01 part of potassium hydroxide and
0.05 part of triethanolamine.
Embodiment 13
The skin care compositions of the present embodiment includes 1 Fen Rou sprout capsule chains algae extract, the hundred of 0.5 part according to the mass fraction
Golden flower extracts, 0.5 part of chrysanthemum coccineum flower extract, 0.1 part of Cortex Phellodendri extract, the extraction of 0.1 part of witch hazel
Object, 0.1 part of safflower seed oil, 0.5 part of pollen, 0.05 part of allantoin, 2 parts of glycerine, 2 parts of 1,3 butylene glycol, 0.5 part
Mannitol, 0.1 part of carbomer, 0.1 part of hydroxyethyl cellulose, 91 parts of distilled water, 0.05 part blood vessel endothelium life
The long factor, 0.1 part of sodium versenate, 0.01 part of potassium hydroxide and 0.05 part of triethanolamine.
Embodiment 14
The skin care compositions of the present embodiment includes 3 Fen Rou sprout capsule chains algae extracts, 1 part of hundred gold medals according to the mass fraction
Flower extract, 1 part of chrysanthemum coccineum flower extract, 0.5 part of Cortex Phellodendri extract, 0.5 part of hamamelis extract, 2
Part safflower seed oil, 1 part of pollen, 0.1 part of allantoin, 1 part of oligopeptides -5,10 parts of glycerine, 5 parts of 1,3 butylene glycol, 1
The mannitol of part, 0.8 part of carbomer, 1.2 parts of hydroxyethyl cellulose, 70 parts of distilled water, the life of 0.3 part of epidermal cell
The long factor and 0.3 part of disodium ethylene diamine tetraacetate, 0.03 part of potassium hydroxide and 0.1 part of triethanolamine.
Embodiment 15
The skin care compositions of the present embodiment includes 3 Fen Rou sprout capsule chains algae extracts, 1 part of hundred gold medals according to the mass fraction
Flower extract, 1 part of chrysanthemum coccineum flower extract, 0.5 part of Cortex Phellodendri extract, 0.5 part of hamamelis extract, 2
Part safflower seed oil, 1 part of pollen, 0.1 part of allantoin, 1 part of oligopeptides -5,10 parts of glycerine, 5 parts of 1,3 butylene glycol, 1
The mannitol of part, 0.8 part of carbomer, 1.2 parts of hydroxyethyl cellulose, 70 parts of distilled water, the life of 0.1 part of epidermal cell
The long factor, 0.1 part of stem cell factor, 0.1 part of vascular endothelial growth factor, 0.3 part of disodium ethylene diamine tetraacetate, 0.03
The potassium hydroxide and 0.1 part of triethanolamine of part.
Embodiment 16
The skin care compositions of the present embodiment includes 3 Fen Rou sprout capsule chains algae extracts, 1 part of hundred gold medals according to the mass fraction
Flower extract, 1 part of chrysanthemum coccineum flower extract, 0.5 part of Cortex Phellodendri extract, 0.5 part of hamamelis extract, 2
Part safflower seed oil, 1 part of pollen, 0.1 part of allantoin, 1 part of oligopeptides -5,10 parts of glycerine, 5 parts of 1,3 butylene glycol, 1
The mannitol, 0.8 part of carbomer, 1.2 parts of hydroxyethyl cellulose, 70 parts of distilled water, 0.3 part of ethylenediamine tetrem of part
Acid disodium, 0.03 part of potassium hydroxide and 0.1 part of triethanolamine.
Embodiment 17
The skin care compositions of the present embodiment, include according to the mass fraction 1.5 Fen Rou sprout capsule chain algae extracts, 0.7 part
Hundred golden flower extracts, 0.6 part of chrysanthemum coccineum flower extract, 0.3 part of Cortex Phellodendri extract, 0.2 part of witch hazel carry
Take object, 1.6 parts of safflower seed oil, 0.8 part of pollen, 0.06 part of allantoin, 0.6 part of oligopeptides -5,7 parts of glycerine, 4 parts
1,3 butylene glycol, 0.8 part of mannitol, 0.5 part of carbomer, 0.8 part of hydroxyethyl cellulose, 80 parts of distilled water,
0.05 part of epithelical cell growth factor, 0.05 part of stem cell factor, 0.05 part of vascular endothelial growth factor, 0.2 part
Disodium ethylene diamine tetraacetate, 0.02 part of potassium hydroxide and 0.06 part of triethanolamine.
Test：
1, organoleptic properties are tested
The skin care compositions of embodiment 6~17 is observed under room temperature and non-direct sunlight respectively, above-mentioned skin care compositions
Equal uniform color, pure in smell.
2, centrefuge experiment
It takes the skin care compositions of the embodiment 6~17 of 5g to be fitted into the centrifuge tube of 10mL respectively, 20 is centrifuged with 3000rpm
Minute, above-mentioned skin care compositions is without lamination.
3, heat-resisting, cold-resistant test
The skin care compositions of the embodiment of 20g 6~17 is positioned in 40 DEG C of insulating box, after 24 hours, is restored respectively
To room temperature, above-mentioned skin care compositions does not occur being layered or deposited phenomenon.
The skin care compositions of the embodiment of 20g 6~17 is positioned in -10 DEG C of insulating box respectively, after 24 hours, is restored
To room temperature, above-mentioned skin care compositions does not occur being layered or deposited phenomenon.
4, biocidal property
The skin care compositions of Examples 1 to 5 is diluted to 1g/L, mixing and filtration sterilization respectively with distilled water, obtains sample
Product solution.The skin care compositions of embodiment 6~17 is diluted to 10g/L, mixing and filtration sterilization respectively with distilled water, obtains sample
Product solution.
(1) to the biocidal property of staphylococcus aureus
Will standard staphylococcus aureus strains activation after be inoculated in beef extract culture medium, in 37 DEG C of sterile cultures for 24 hours after,
It is 10 to draw bacterium solution and be diluted to bacteria concentration with beef extract culture medium5CFU/mL~106CFU/mL obtains bacteria suspension.In sterile working
Under the conditions of, above-mentioned bacteria suspension is taken, is uniformly applied on beef extract agar medium with spreading rod.It is with sterile tweezer that Oxford cup is light again
It is placed on the media surface of solidification, it is light that Oxford cup is pressed to keep contact good.The sample solution of 50 μ L is drawn in ox with micro sample adding appliance
In the cup of Tianjin, 37 DEG C of incubator cultures are taken out afterwards for 24 hours, and the straight of the effective inhibition zone of test liquid in each culture dish is accurately measured with slide calliper rule
Diameter.Each sample solution is repeated 3 times measurement, and takes average value three times.Wherein, it is sky to only have beef extract agar medium
White control group, to be coated with bacteria suspension and inject into Oxford cup the sterile water of 50 μ L as negative control group, to be coated with bacteria suspension simultaneously
50 μ L are injected into Oxford cup, the erythromycin of 1g/L is positive controls.Measurement result refers to table 1.
(2) to the biocidal property of propionibacterium acnes
It is inoculated in brain-heart infusion medium after standard propionibacterium acnes bacterial strain is activated, in 37 DEG C of anaerobism sterile cultures
After 48h, it is 10 to draw bacterium solution and be diluted to bacteria concentration with beef extract culture medium5CFU/mL~106CFU/mL obtains bacteria suspension.In nothing
Under bacterium operating condition, above-mentioned bacteria suspension is taken, is uniformly applied on brain heart infusion solid medium with spreading rod.It again will with sterile tweezer
Oxford cup puts down the media surface in solidification gently, light that Oxford cup is pressed to keep contact good.The sample of 50 μ L is drawn with micro sample adding appliance
Solution takes out after 37 DEG C of incubator culture 48h in Oxford cup, it is effectively antibacterial that test liquid in each culture dish is accurately measured with slide calliper rule
The diameter of circle.Each sample solution is repeated 3 times measurement, and takes average value three times.Wherein, to only have the training of brain heart infusion solid
It is blank control group to support base, to be coated with bacteria suspension and inject into Oxford cup the sterile water of 50 μ L as negative control group, with coating
Bacteria suspension and injected into Oxford cup 50 μ L, 1g/L erythromycin be positive controls.Measurement result refers to table 1.
The biocidal property of the skin care compositions of 1 embodiment 1~16 of table
Experiment proves that blank control group and negative control group do not occur inhibition zone.As it can be seen from table 1 embodiment 1
~3, embodiment 6~7 and the antibacterial circle diameter of the staphylococcus aureus of the skin care compositions of embodiment 10~17 are at least
The antibacterial circle diameter of 20.3mm, propionibacterium acnes are at least 18.7mm, illustrate above-mentioned Ji Yu Rou sprouts capsule chain algae extract
Skin care compositions all has inhibiting effect to staphylococcus aureus and propionibacterium acnes, can preferably inhibit by golden yellow
Inflammation caused by least one of staphylococcus and propionibacterium acnes.
Wherein, the antibacterial circle diameter of the staphylococcus aureus of the skin care compositions of embodiment 6 is more than embodiment 8~7
The antibacterial circle diameter of skin care compositions, and the antibacterial circle diameter of the propionibacterium acnes of the skin care compositions of embodiment 6 is more than in fact
The antibacterial circle diameter for applying the propionibacterium acnes of the skin care compositions of example 8~9, Shuos Ming Rou sprout capsule chain algae extract and Cortex Phellodendri
Extract acts synergistically, and is more advantageous to the fungistatic effect for improving above-mentioned skin care compositions.
5, skin proof test
(1) skin care compositions that the volunteer that the age is 28 years old~36 years old is prepared using embodiment 6~17 is daily
Skin care is carried out after face cleaning, usage time is 30 days, and volunteer's every morning and evening are carried out using the composition of the present invention respectively
Skin care, application method are specially：It takes the composition 2mL of the present invention to be uniformly applied to skin of face, smears 5 minutes.Wherein, each
Embodiment has 20 volunteers to use.It should be noted that other skin nursing situations one of above-mentioned all volunteers
It causes.
Above-mentioned volunteer states progress skin index test in the 1st day and the 30th day of skin care compositions in use, random to take out
It takes 5 volunteers therein to test, and calculates the average value of parameters, test result is as shown in table 2.Skin is carried out to refer to
When number test, tested using moisture of skin index tester (Fes Kai Er).The ideal value of moisture be 40%~
60%, the ideal value of oil content is 15%~20%, and the ideal value of coefficient of elasticity is 0.45~0.55.
The skin of the skin care compositions of 2 embodiment 6~17 of table tries out test result
From table 2 it can be seen that using after the skin care compositions of embodiment 6~7 and embodiment 10~17, the face of volunteer
Moisture and coefficient of elasticity be improved, oil content decline, face lack moisture and elasticity phenomenon obtain significantly
Improve, illustrates that the skin care compositions of above-mentioned Ji Yu Rou sprouts capsule chain algae extract has the effect of preferable moisturizing, skin can be alleviated
Skin relaxes, and reduces skin lines and wrinkle；Secondly, above-mentioned all volunteers do not occur skin allergy, skin pimples, long acne
Etc. irritability reaction, illustrate that above-mentioned skin care compositions is safe and free of toxic and side effects.
The skin care compositions of embodiment 6 is superior to reality to the improvement of the moisture of face, oil content and coefficient of elasticity
The effect for applying the skin care compositions of example 8~9, Ming Rou sprout capsule chain algae extracts of Shuoing act synergistically more advantageous with Cortex Phellodendri extract
In the moisture for improving skin, enhance the elasticity of skin.12 skin care compositions of embodiment is better than the improvement of the coefficient of elasticity of face
The effect of 6 skin care compositions of embodiment illustrates that the addition of renovation agent is conducive to improve the elasticity of skin, to desalinate microgroove and wrinkle
Line keeps the younger state of skin.14 skin care compositions of embodiment protects the improvement of the coefficient of elasticity of face better than embodiment 13
The effect of skin composition illustrates a variety of renovation agent synergistic effects, can further increase the elasticity of skin.
(2) volunteer for suffering from acne that the age is 28 years old~36 years old is as subject, using the skin care of embodiment 6~17
Composition carries out skin care after daily face cleaning, and usage time is 30 days.Application method：It is applied outside at skin lesion after subject's face cleaning
One layer of above-mentioned each skin care compositions, each 1 time daily morning and evening.With reference to《New Chinese medicine guideline of clinical investigations》, calculate skin lesion and disappear
It moves back rate and confirms curative effect, wherein the criterion of curative effect is：Recovery from illness is that skin lesion extinction rate is more than 90%, and only a little pigment is heavy
It；Be skin lesion extinction rate it is effectively significantly 60%~90%, symptom mitigation；Be skin lesion extinction rate it is effectively 20~60%, symptom
Improve；It is less than 20% in vain for skin lesion extinction rate, clinical symptoms do not improve, and cure rate be the number fully recovered and the ratio between total number of persons,
Measurement result refers to table 3.Meanwhile determining the number of onset time and different onset times, onset time subtracts for symptom after medication
Gently, skin lesion extinction rate is more than 20% or more number of days, and measurement result refers to table 4.
Function and effect of the skin care compositions of 3 embodiment 6~17 of table to acne
| It fully recovers (people) | Significantly effectively (people) | Effectively (people) | (people) in vain | Cure rate (%) | |
| Embodiment 6 | 12 | 5 | 2 | 1 | 60 |
| Embodiment 7 | 13 | 4 | 2 | 1 | 65 |
| Embodiment 8 | 8 | 6 | 3 | 3 | 40 |
| Embodiment 9 | 10 | 5 | 4 | 1 | 50 |
| Embodiment 10 | 13 | 5 | 2 | 0 | 65 |
| Embodiment 11 | 13 | 6 | 1 | 0 | 65 |
| Embodiment 12 | 16 | 4 | 0 | 0 | 80 |
| Embodiment 13 | 15 | 5 | 0 | 0 | 75 |
| Embodiment 14 | 17 | 2 | 0 | 0 | 85 |
| Embodiment 15 | 18 | 1 | 0 | 0 | 90 |
| Embodiment 16 | 16 | 3 | 1 | 0 | 80 |
| Embodiment 17 | 14 | 3 | 3 | 0 | 70 |
From table 3 it can be seen that the skin care compositions of embodiment 6~7 and embodiment 10~17 to the cure rate of acne extremely
It is less 65%, illustrates that above-mentioned Ji Yu Rou sprout capsule chain algae extracts have preferable curative effect to acne.Wherein, embodiment 6
The cure rate of skin care compositions is substantially better than the cure rate of the skin care compositions of embodiment 8~9, Shuos Ming Rou sprout capsule chain algae extract
It acts synergistically with Cortex Phellodendri extract, therapeutic effect of the skin care compositions to acne can be remarkably reinforced.Embodiment 12 and 13
Skin care compositions cure rate higher than embodiment 6 skin care compositions cure rate, illustrate that the addition of renovation agent can improve
Skin care compositions to the therapeutic effect of acne, meanwhile, the cure rate of the skin care compositions of embodiment 15 is higher than the shield of embodiment 14
The cure rate of skin composition illustrates a variety of renovation agent synergistic effects, can further increase treatment of the skin care compositions to acne
Effect.
Function and effect of the skin care compositions of 4 embodiment 6~17 of table to acne
From table 4, it can be seen that using after the skin care compositions of embodiment 6~7 and embodiment 10~17, equal at least 8 people
Onset time be 1 day~3 days, illustrate that above-mentioned Ji Yu Rou sprout capsule chain algae extract is fast to responding well to treatment for acne.Wherein, it uses
The number that the onset time of the skin care compositions of embodiment 6 is 1 day~3 days is significantly more than the skincare composition using embodiment 8~9
The number that the onset time of object is 1 day~3 days, Ming Rou sprout capsule chain algae extracts of Shuoing act synergistically with Cortex Phellodendri extract, make
Above-mentioned skin care compositions being capable of quickly removing acne.Onset time using the skin care compositions of embodiment 12 and 13 is 1
It~3 days numbers are more than the number for the use of the onset time of embodiment 6 being 1 day~3 days, illustrate that the addition of renovation agent makes
The effect of removing acne can quickly be played by stating skin care compositions, meanwhile, use the action of the skin care compositions of embodiment 15
The number that it is 1 day~3 days using the onset time of the skin care compositions of embodiment 14 that the number that time is 1 day~3 days, which is higher than, says
Bright a variety of renovation agent synergistic effects, can further speed up the effect that skin care compositions plays removing acne.
Each technical characteristic of embodiment described above can be combined arbitrarily, to keep description succinct, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, it is all considered to be the range of this specification record.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention
Range.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (10)
1. a kind of skin care compositions of Ji Yu Rou sprouts capsule chain algae extract, which is characterized in that including active component, the activearm
Include point based on mass fraction 1 part~3 Fen Rou sprout capsule chains algae extracts, 0.5 part~1 part of hundred golden flower extracts, 0.5 part~
1 part of chrysanthemum coccineum flower extract, 0.1 part~0.5 part of Cortex Phellodendri extract and 0.1 part~0.5 part of witch hazel carry
Take object.
2. the skin care compositions of Ji Yu Rou sprouts capsule chain algae extract according to claim 1, which is characterized in that the activity
Component further includes 0.1 part~2 parts of safflower seed oil based on mass fraction.
3. the skin care compositions of Ji Yu Rou sprouts capsule chain algae extract according to claim 2, which is characterized in that the activity
Component includes 1.5 parts~2.5 Fen Rou sprout capsule chains algae extracts, 0.6 part~0.8 part of hundred golden flower extractions based on mass fraction
Object, 0.6 part~0.8 part of chrysanthemum coccineum flower extract, 0.2 part~0.4 part of Cortex Phellodendri extract, 0.2 part~0.4 part
Hamamelis extract and 0.5 part~1.5 parts of safflower seed oil.
4. the skin care compositions of Ji Yu Rou sprouts capsule chain algae extract according to claim 1, which is characterized in that the activity
Component further includes 0.5 part~1 part of pollen and 0.05 part~0.1 part of allantoin based on mass fraction.
5. the skin care compositions of Ji Yu Rou sprouts capsule chain algae extract according to claim 1, which is characterized in that the activity
Component further includes 0.1 part~1 part of oligopeptides -5 based on mass fraction.
6. the skin care compositions of Ji Yu Rou sprouts capsule chain algae extract according to claim 1, which is characterized in that further include protecting
Humectant, thickener and solvent, the active component, the moisturizer, the thickener and the solvent mass ratio be " 4~
9”:" 2.5~16 ":" 0.2~2 ":" 70~91 ".
7. the skin care compositions of Ji Yu Rou sprouts capsule chain algae extract according to claim 6, which is characterized in that the moisturizing
Agent includes 2 parts~10 parts of glycerine, 2 parts~5 parts of 1,3 butylene glycol and 0.5 part~1 part of mannitol based on mass fraction.
8. the skin care compositions of Ji Yu Rou sprouts capsule chain algae extract according to claim 6, which is characterized in that the thickening
Agent in terms of mass fraction including 0.1 part~0.8 part of carbomer and 0.1 part~1.2 parts of hydroxyethyl cellulose.
9. the skin care compositions of Ji Yu Rou sprouts capsule chain algae extract according to claim 6, which is characterized in that the solvent
Selected from least one of distilled water and deionized water.
10. the skin care compositions of Ji Yu Rou sprouts capsule chain algae extract according to any one of claims 1 to 9 is in skin care item
Using.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104840490A (en) * | 2008-10-31 | 2015-08-19 | 比诺里卡公司 | Plant extract hydrolysates and antibacterial product containing the same |
| CN105434307A (en) * | 2015-12-16 | 2016-03-30 | 广州市中通生化制品有限公司 | Acne-removing cream containing Chinese herbal medicine extracts and preparation method thereof |
| CN107308027A (en) * | 2017-07-11 | 2017-11-03 | 广州市巧美化妆品有限公司 | A kind of succinct production technology of sapphire whitening |
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| CN104840490A (en) * | 2008-10-31 | 2015-08-19 | 比诺里卡公司 | Plant extract hydrolysates and antibacterial product containing the same |
| CN105434307A (en) * | 2015-12-16 | 2016-03-30 | 广州市中通生化制品有限公司 | Acne-removing cream containing Chinese herbal medicine extracts and preparation method thereof |
| CN107308027A (en) * | 2017-07-11 | 2017-11-03 | 广州市巧美化妆品有限公司 | A kind of succinct production technology of sapphire whitening |
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