CN107308027A - A kind of succinct production technology of sapphire whitening - Google Patents
A kind of succinct production technology of sapphire whitening Download PDFInfo
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- CN107308027A CN107308027A CN201710563443.5A CN201710563443A CN107308027A CN 107308027 A CN107308027 A CN 107308027A CN 201710563443 A CN201710563443 A CN 201710563443A CN 107308027 A CN107308027 A CN 107308027A
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- Prior art keywords
- whitening
- sapphire
- succinct
- production technology
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of succinct production technology of sapphire whitening, this method comprises the following steps：A, harvesting and dry Europe capsule chain algae；Europe capsule chain algae extract is extracted using enzymatic method；Heating inactivates enzyme；Add glycerine and preservative；Sterilising filtration is that can obtain sapphire whitening essence；The sapphire whitening essence of the present invention is a kind of clear liquid with characteristic chicken flavor；The succinct main component is Europe capsule chain algae extract, and the extract obtained using enzymatic method in preparation process of the invention can significantly inhibit the synthesis of POMC (preceding melanotropin)；Prevent melanocyte from producing melanin；The melanin being already present in epidermis is beaten back, with extraordinary whitening function.
Description
Technical field
The present invention relates to cosmetics processing technique field, the succinct production technology of more particularly to a kind of sapphire whitening.
Background technology
Europe capsule chain algae (CYSTOSEIRA TAMARISCIFOLIA) belongs to the brown marine alga of Fucales.It is an introduces a collection
From deep-sea, such as sapphire, blue glare can be sent, colorful is in riotous profusion, the marine alga that can change colour, and we term it " ocean blue
This marine alga of jewel " is found in West Europe：From the south of UK ＆ Ireland and western bank, to Scottish the north, France and
The Hispanic Atlantic Ocean.This unique marine alga can grow into 60 centimeter lengths, when being submerged in water or meeting under wet condition
Send the brilliance of substantially green or blueness.
In terms of its whitening function mainly includes three below：
1st, the synthesis of POMC (preceding melanotropin) is significantly inhibited；
2nd, prevent melanocyte from producing melanin；
3rd, the melanin being already present in epidermis is beaten back.
In order to preferably play the whitening effect of Europe capsule chain algae, the invention provides a kind of succinct production of sapphire whitening
Technique.
The content of the invention
In order to solve the above technical problems, the present invention provides a kind of sapphire whitening succinct production technology.
A kind of succinct production technology of sapphire whitening, comprises the following steps：
A, harvesting and dry Europe capsule chain algae；
B, using enzymatic method extract Europe capsule chain algae extract；
C, heating inactivate enzyme；
D, addition glycerine and preservative；
E, sterilising filtration are that can obtain sapphire whitening essence.
It is preferred that, in described step A, in drying process, drying temperature preferably is 45-55 DEG C, and the time is that 4-6 is small
When.
It is preferred that, in described step B, using in enzymatic method extraction process, the enzyme of selection is protease, amylase and Portugal
The mixed enzyme of dextranase composition.
It is preferred that, in described step C, heating-up temperature is 70-80 DEG C, and the time is 10-20 minutes.
It is preferred that, in described step E, sterilizing is using 0.2 μm of sterilizing filter filtering.
It is preferred that, in described step E, during described sapphire whitening is succinct, the percentage by weight of each raw material is as follows：
Glycerine 48.5-50.5%
Europe capsule chain algae extract 0.8-1.5%
Phenoxyethanol 0.5-1.2%
Water 47.5-49.5%.
It is further preferred that in described step E, during described sapphire whitening is succinct, the percentage by weight of each raw material
It is as follows：
Glycerine 49.5%
Europe capsule chain algae extract 1.0%
Phenoxyethanol 1.0%
Water 48.5%.
Beneficial effects of the present invention are：The sapphire whitening essence of the present invention is a kind of limpid liquid with characteristic chicken flavor
Body；The succinct main component is Europe capsule chain algae extract, the extract obtained using enzymatic method in preparation process of the invention
The synthesis of POMC (preceding melanotropin) can be significantly inhibited；Prevent melanocyte from producing melanin；Beat back and be already present on epidermis
In melanin, with extraordinary whitening function.
Brief description of the drawings
Fig. 1：The compound experiment compares figure of melanotropin (POMC) before reduction.
Fig. 2：Reduce the maturing experiment contrast figure of corticotropin (ACTH).
Fig. 3：Reduce the compound experiment compares figure of PMEL17 genes.
Fig. 4：Reduce the compound experiment compares figure of melanin.
Embodiment
With reference to embodiment, the embodiment to the present invention is described in further detail.Following examples are used for
Illustrate the present invention, but be not limited to the scope of the present invention.
Embodiment 1
A kind of succinct production technology of sapphire whitening, comprises the following steps：
A, harvesting and dry Europe capsule chain algae；
B, using enzymatic method extract Europe capsule chain algae extract；
C, heating inactivate enzyme；
D, addition glycerine and preservative；
E, sterilising filtration are that can obtain sapphire whitening essence.
In described step A, in drying process, drying temperature preferably is 50 DEG C, and the time is 4 hours.
In described step B, using in enzymatic method extraction process, the enzyme of selection is protease, amylase and dextranase
The mixed enzyme of composition.
In described step C, heating-up temperature is 75 DEG C, and the time is 15 minutes.
In described step E, sterilizing is using 0.2 μm of sterilizing filter filtering.
In described step E, during described sapphire whitening is succinct, the percentage by weight of each raw material is as follows：
Glycerine 49.5%
Europe capsule chain algae extract 1.0%
Phenoxyethanol 1.0%
Water 48.5%.
Embodiment 2
A kind of succinct production technology of sapphire whitening, comprises the following steps：
A, harvesting and dry Europe capsule chain algae；
B, using enzymatic method extract Europe capsule chain algae extract；
C, heating inactivate enzyme；
D, addition glycerine and preservative；
E, sterilising filtration are that can obtain sapphire whitening essence.
In described step A, in drying process, drying temperature preferably is 55 DEG C, and the time is 4 hours.
In described step B, using in enzymatic method extraction process, the enzyme of selection is protease, amylase and dextranase
The mixed enzyme of composition.
In described step C, heating-up temperature is 80 DEG C, and the time is 10 minutes.
In described step E, sterilizing is using 0.2 μm of sterilizing filter filtering.
In described step E, during described sapphire whitening is succinct, the percentage by weight of each raw material is as follows：
Glycerine 50.5%
Europe capsule chain algae extract 0.8%
Phenoxyethanol 1.2%
Water 47.5%.
Embodiment 3
A kind of succinct production technology of sapphire whitening, comprises the following steps：
A, harvesting and dry Europe capsule chain algae；
B, using enzymatic method extract Europe capsule chain algae extract；
C, heating inactivate enzyme；
D, addition glycerine and preservative；
E, sterilising filtration are that can obtain sapphire whitening essence.
In described step A, in drying process, drying temperature preferably is 45 DEG C, and the time is 6 hours.
In described step B, using in enzymatic method extraction process, the enzyme of selection is protease, amylase and dextranase
The mixed enzyme of composition.
In described step C, heating-up temperature is 70 DEG C, and the time is 20 minutes.
In described step E, sterilizing is using 0.2 μm of sterilizing filter filtering.
In described step E, during described sapphire whitening is succinct, the percentage by weight of each raw material is as follows：
Glycerine 48.5%
Europe capsule chain algae extract 1.5%
Phenoxyethanol 0.5%
Water 49.5%.
The whitening effect and mechanism of the sapphire whitening essence prepared below by way of specific experiment to embodiment 1 are visited
Beg for, it is specific as follows：
Experiment 1：The compound experiment of melanotropin (POMC) before reduction
Preceding melanotropin (POMC) is a kind of gene, can promote α-MSH secretion, so as to trigger the generation of melanin.
Experimental method：Rebuild the human epidermal of black；The sapphire whitening of topical application 1% essence continuously makes in cream
With 16 days；Pass through the expression of PCR array analysis pomc genes.
As a result：As shown in Figure 1：Sapphire whitening is succinct to be reduced to the POMC influences synthesized compared to blank control group
46%, melanotropin POMC synthesis before sapphire whitening essence can be reduced, therefore, it is possible to reduce α-MSH and melanin production
It is raw.
Experiment 2：Reduce the maturing experiment of corticotropin (ACTH)
Experimental method：Rebuild the human epidermal of black；The sapphire whitening of topical application 1% essence continuously makes in cream
With 16 days；Pass through the expression of PCR array analysis pomc genes.
As a result：As shown in Figure 2：SCTE and ST14 are the genes of encoding proteins enzyme, can participate in preceding melanotropin (POMC) raw
Into corticotropin (ACTH), and activation melanin generation.
Experiment 3：Reduce the compound experiment of PMEL17 genes
The effect of PMEL17 genes：
1st, the activation of melanin：Under ultraviolet irradiation, keratinocyte can discharge preceding melanotropin --- POMC, when
When a-MSH combines its acceptor MC1r, it can activate the synthesis of melanin；2nd, the maturing of melanosome：PMEL17 genes ensure black
The maturation of ferritic；3rd, the synthesis of melanin：Pass through the activity of tyrosinase, melanosome synthesis of melanin.
Experimental method：Rebuild the human epidermal of black；The sapphire whitening of topical application 1% essence continuously makes in cream
With 16 days；Synthesize to analyze the situation of PMEL17 genes by immune labeled analysing protein.
As a result：As shown in Figure 3：The succinct influence to PMEL17 genes of sapphire whitening is reduced compared to blank control group
25%.
Experiment 4：Reduce the compound experiment of melanin
Experimental method：Rebuild the human epidermal of black；The sapphire whitening of topical application 1% essence continuously makes in cream
With 16 days；The coloring of quantitative analysis melanin.
As a result：As shown in Figure 4：The influence of the succinct coloring to melanin of sapphire whitening is compared to blank control group reduction
90%.
In summary：The succinct synthesis by significantly inhibiting POMC (preceding melanotropin) of the sapphire whitening of the present invention；It is anti-
Only melanocyte produces melanin；Beat back the melanin being already present in epidermis and reach extraordinary whitening effect.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, without departing from the technical principles of the invention, some improvement and modification can also be made, these improvement and modification
Also it should be regarded as protection scope of the present invention.
Claims (7)
1. the succinct production technology of a kind of sapphire whitening, it is characterised in that comprise the following steps：
A, harvesting and dry Europe capsule chain algae；
B, using enzymatic method extract Europe capsule chain algae extract；
C, heating inactivate enzyme；
D, addition glycerine and preservative；
E, sterilising filtration are that can obtain sapphire whitening essence.
2. the succinct production technology of sapphire whitening as claimed in claim 1, it is characterised in that in described step A, is dried
During, drying temperature preferably is 45-55 DEG C, and the time is 4-6 hours.
3. the succinct production technology of sapphire whitening as claimed in claim 1, it is characterised in that in described step B, is used
In enzymatic method extraction process, the enzyme of selection is the mixed enzyme of protease, amylase and dextranase composition.
4. the succinct production technology of sapphire whitening as claimed in claim 1, it is characterised in that in described step C, heating
Temperature is 70-80 DEG C, and the time is 10-20 minutes.
5. the succinct production technology of sapphire whitening as claimed in claim 1, it is characterised in that in described step E, sterilizing
Filtered using 0.2 μm of sterilizing filter.
6. the succinct production technology of sapphire whitening as claimed in claim 1, it is characterised in that described in described step E
Sapphire whitening it is succinct in, the percentage by weight of each raw material is as follows：
Glycerine 48.5-50.5%
Europe capsule chain algae extract 0.8-1.5%
Phenoxyethanol 0.5-1.2%
Water 47.5-49.5%.
7. the succinct production technology of sapphire whitening as claimed in claim 6, it is characterised in that described in described step E
Sapphire whitening it is succinct in, the percentage by weight of each raw material is as follows：
Glycerine 49.5%
Europe capsule chain algae extract 1.0%
Phenoxyethanol 1.0%
Water 48.5%.
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| CN201710563443.5A CN107308027A (en) | 2017-07-11 | 2017-07-11 | A kind of succinct production technology of sapphire whitening |
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| CN201710563443.5A CN107308027A (en) | 2017-07-11 | 2017-07-11 | A kind of succinct production technology of sapphire whitening |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108158865A (en) * | 2018-01-12 | 2018-06-15 | 广州赛莱拉干细胞科技股份有限公司 | The reparation makeup removing breast of Europe capsule chain algae extract |
| CN108379153A (en) * | 2018-04-17 | 2018-08-10 | 广州赛莱拉干细胞科技股份有限公司 | The skin care compositions of Ji Yu Rou sprout capsule chain algae extracts and its application |
| FR3074045A1 (en) * | 2017-11-30 | 2019-05-31 | Societe De Courtage Et De Diffusion | COSMETIC COMPOSITION WITH ALGAE EXTRACT CYSTOSEIRA TAMARISCIFOLIA. |
| CN112933011A (en) * | 2021-03-04 | 2021-06-11 | 肌源匙(广东)皮肤管理科技有限公司 | Whitening composition and preparation process and application thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3074045A1 (en) * | 2017-11-30 | 2019-05-31 | Societe De Courtage Et De Diffusion | COSMETIC COMPOSITION WITH ALGAE EXTRACT CYSTOSEIRA TAMARISCIFOLIA. |
| CN108158865A (en) * | 2018-01-12 | 2018-06-15 | 广州赛莱拉干细胞科技股份有限公司 | The reparation makeup removing breast of Europe capsule chain algae extract |
| CN108379153A (en) * | 2018-04-17 | 2018-08-10 | 广州赛莱拉干细胞科技股份有限公司 | The skin care compositions of Ji Yu Rou sprout capsule chain algae extracts and its application |
| CN112933011A (en) * | 2021-03-04 | 2021-06-11 | 肌源匙(广东)皮肤管理科技有限公司 | Whitening composition and preparation process and application thereof |
| CN112933011B (en) * | 2021-03-04 | 2021-12-28 | 肌源匙(广东)皮肤管理科技有限公司 | Whitening composition and preparation process and application thereof |
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| CB03 | Change of inventor or designer information |
Inventor after: Zhang Jian Inventor after: Antoine Geduin Inventor after: Pierre Eve Inventor after: Romualz Ballet Inventor before: Zhang Jian |
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Application publication date: 20171103 |
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