CN1083048A - 杂环化合物 - Google Patents

杂环化合物 Download PDF

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Publication number
CN1083048A
CN1083048A CN93105698A CN93105698A CN1083048A CN 1083048 A CN1083048 A CN 1083048A CN 93105698 A CN93105698 A CN 93105698A CN 93105698 A CN93105698 A CN 93105698A CN 1083048 A CN1083048 A CN 1083048A
Authority
CN
China
Prior art keywords
compound
alkyl
group
formula
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN93105698A
Other languages
English (en)
Chinese (zh)
Inventor
A·T·哈德林
C·L·易斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Group
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Group filed Critical Wellcome Foundation Group
Publication of CN1083048A publication Critical patent/CN1083048A/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C271/34—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN93105698A 1992-04-06 1993-04-05 杂环化合物 Withdrawn CN1083048A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929207517A GB9207517D0 (en) 1992-04-06 1992-04-06 Heterocyclic compounds
GB9207517.5 1992-04-06

Publications (1)

Publication Number Publication Date
CN1083048A true CN1083048A (zh) 1994-03-02

Family

ID=10713546

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93105698A Withdrawn CN1083048A (zh) 1992-04-06 1993-04-05 杂环化合物

Country Status (16)

Country Link
EP (1) EP0634996A1 (fr)
JP (1) JPH07505388A (fr)
KR (1) KR950700874A (fr)
CN (1) CN1083048A (fr)
AU (1) AU3899293A (fr)
CA (1) CA2133744A1 (fr)
CZ (1) CZ242994A3 (fr)
FI (1) FI944657A (fr)
GB (1) GB9207517D0 (fr)
HU (1) HUT68937A (fr)
IL (1) IL105322A0 (fr)
MX (1) MX9301962A (fr)
NO (1) NO943737L (fr)
SK (1) SK120994A3 (fr)
WO (1) WO1993020044A1 (fr)
ZA (1) ZA932458B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013093937A2 (fr) * 2011-09-16 2013-06-27 Alkem Laboratories Ltd. Promédicament de ''3-(5-méthyl-2-oxo-l, 3-dioxol-4-yl) méthyloxy-2- trans-[(4-chlorophényl) cyclohexyl] [1,4]naphtaquinone"-atovaquone
MA45411A (fr) 2016-06-20 2019-04-24 Scripps Research Inst Compositions antimalariques et leurs utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485116A (en) * 1981-10-16 1984-11-27 Hudson Alan T Antiprotozoal compounds
GB8310141D0 (en) * 1983-04-14 1983-05-18 Wellcome Found Naphthoquinone derivatives
EP0362996B1 (fr) * 1988-08-16 1994-04-27 The Wellcome Foundation Limited Naphtoquinones pour le traitement et prophylaxe des infections de pneumocystis carinii

Also Published As

Publication number Publication date
HUT68937A (en) 1995-08-28
GB9207517D0 (en) 1992-05-20
ZA932458B (en) 1994-10-05
FI944657A (fi) 1994-12-02
NO943737L (no) 1994-11-29
WO1993020044A1 (fr) 1993-10-14
SK120994A3 (en) 1995-07-11
NO943737D0 (no) 1994-10-05
AU3899293A (en) 1993-11-08
EP0634996A1 (fr) 1995-01-25
JPH07505388A (ja) 1995-06-15
IL105322A0 (en) 1993-08-18
CZ242994A3 (en) 1995-06-14
KR950700874A (ko) 1995-02-20
HU9402850D0 (en) 1995-01-30
CA2133744A1 (fr) 1993-10-14
FI944657A0 (fi) 1994-10-05
MX9301962A (es) 1993-11-01

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C03 Withdrawal of patent application (patent law 1993)
WW01 Invention patent application withdrawn after publication