AU3899293A - 1,4 naphthoquinone derivtives with anti-protozoal and anti-parasitic activity - Google Patents

1,4 naphthoquinone derivtives with anti-protozoal and anti-parasitic activity

Info

Publication number
AU3899293A
AU3899293A AU38992/93A AU3899293A AU3899293A AU 3899293 A AU3899293 A AU 3899293A AU 38992/93 A AU38992/93 A AU 38992/93A AU 3899293 A AU3899293 A AU 3899293A AU 3899293 A AU3899293 A AU 3899293A
Authority
AU
Australia
Prior art keywords
group
compound
formula
compounds
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU38992/93A
Other languages
English (en)
Inventor
Alan Thomas Hudson
Clive Leonard Yeates
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of AU3899293A publication Critical patent/AU3899293A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C271/34—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU38992/93A 1992-04-06 1993-04-05 1,4 naphthoquinone derivtives with anti-protozoal and anti-parasitic activity Abandoned AU3899293A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929207517A GB9207517D0 (en) 1992-04-06 1992-04-06 Heterocyclic compounds
GB9207517 1992-04-06

Publications (1)

Publication Number Publication Date
AU3899293A true AU3899293A (en) 1993-11-08

Family

ID=10713546

Family Applications (1)

Application Number Title Priority Date Filing Date
AU38992/93A Abandoned AU3899293A (en) 1992-04-06 1993-04-05 1,4 naphthoquinone derivtives with anti-protozoal and anti-parasitic activity

Country Status (16)

Country Link
EP (1) EP0634996A1 (fr)
JP (1) JPH07505388A (fr)
KR (1) KR950700874A (fr)
CN (1) CN1083048A (fr)
AU (1) AU3899293A (fr)
CA (1) CA2133744A1 (fr)
CZ (1) CZ242994A3 (fr)
FI (1) FI944657A (fr)
GB (1) GB9207517D0 (fr)
HU (1) HUT68937A (fr)
IL (1) IL105322A0 (fr)
MX (1) MX9301962A (fr)
NO (1) NO943737L (fr)
SK (1) SK120994A3 (fr)
WO (1) WO1993020044A1 (fr)
ZA (1) ZA932458B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013093937A2 (fr) * 2011-09-16 2013-06-27 Alkem Laboratories Ltd. Promédicament de ''3-(5-méthyl-2-oxo-l, 3-dioxol-4-yl) méthyloxy-2- trans-[(4-chlorophényl) cyclohexyl] [1,4]naphtaquinone"-atovaquone
MA45411A (fr) 2016-06-20 2019-04-24 Scripps Research Inst Compositions antimalariques et leurs utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485116A (en) * 1981-10-16 1984-11-27 Hudson Alan T Antiprotozoal compounds
GB8310141D0 (en) * 1983-04-14 1983-05-18 Wellcome Found Naphthoquinone derivatives
EP0362996B1 (fr) * 1988-08-16 1994-04-27 The Wellcome Foundation Limited Naphtoquinones pour le traitement et prophylaxe des infections de pneumocystis carinii

Also Published As

Publication number Publication date
HUT68937A (en) 1995-08-28
GB9207517D0 (en) 1992-05-20
ZA932458B (en) 1994-10-05
FI944657A (fi) 1994-12-02
NO943737L (no) 1994-11-29
WO1993020044A1 (fr) 1993-10-14
CN1083048A (zh) 1994-03-02
SK120994A3 (en) 1995-07-11
NO943737D0 (no) 1994-10-05
EP0634996A1 (fr) 1995-01-25
JPH07505388A (ja) 1995-06-15
IL105322A0 (en) 1993-08-18
CZ242994A3 (en) 1995-06-14
KR950700874A (ko) 1995-02-20
HU9402850D0 (en) 1995-01-30
CA2133744A1 (fr) 1993-10-14
FI944657A0 (fi) 1994-10-05
MX9301962A (es) 1993-11-01

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