CN108261387B - Moisturizing, nourishing and whitening mask base solution and preparation method thereof - Google Patents

Moisturizing, nourishing and whitening mask base solution and preparation method thereof Download PDF

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Publication number
CN108261387B
CN108261387B CN201810228352.0A CN201810228352A CN108261387B CN 108261387 B CN108261387 B CN 108261387B CN 201810228352 A CN201810228352 A CN 201810228352A CN 108261387 B CN108261387 B CN 108261387B
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skin
nourishing
moisturizing
parts
deionized water
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CN108261387A (en
Inventor
刘继勇
钱丹
顾永卫
吴建华
施倩倩
顾清
唐晓萌
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Jiangsu Sufu Science And Technology Development Co Ltd
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Jiangsu Sufu Science And Technology Development Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/671Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to the technical field of skin care products, and provides a moisturizing, nourishing and whitening mask base solution as well as a preparation method and application thereof. The main components of the pearl health-care product comprise pearl hydrolysate, ginseng extract, ligusticum wallichii extract, vitamin E, glycerol, allantoin, propylene glycol, zinc gluconate, tretinoin, vitamin B6, 2, 6-tert-butyl-p-cresol, carbomer 940, preservative, ethanol, triethanolamine and deionized water. The moisturizing, nourishing and whitening mask base solution prepared by the invention has the characteristics of clarity, transparency, proper consistency, easiness in absorption, no stimulation to skin and the like; is suitable for four seasons, can regulate sebum secretion, provides sufficient moisture for skin, realizes deep nourishing, makes skin white, tight and elastic, and improves the skin problems of dull, dry, desquamation and the like.

Description

Moisturizing, nourishing and whitening mask base solution and preparation method thereof
Technical Field
The invention relates to the technical field of skin care products, and particularly relates to a moisturizing, nourishing and whitening mask base solution and a preparation method thereof.
Background
In modern times, people have higher and higher requirements on the condition of facial skin, but as the people age, a large number of free radicals are generated by the human body, cells are damaged, the problems of wrinkles, aging, dark skin color and the like can occur to the skin, particularly the problems of dryness, chapping and the like easily occur to the skin in autumn and winter, and particularly, the air pollution causes further damage to the skin. Therefore, there is an increasing demand for non-chemical products that can effectively retain moisture in the skin and increase the elasticity of the skin for a long period of time. The water-based components in the facial mask base solution can provide lasting moisture for the skin, and the oil-based components in the base solution can nourish the skin, so that the facial mask base solution has good moisturizing and nourishing effects on the skin.
Disclosure of Invention
The invention aims to provide a mask base solution with the functions of moisturizing, nourishing and whitening, another purpose of the invention is to provide a preparation method of the mask base solution, and a third purpose of the invention is to provide an application of the mask base solution in skin moisturizing, nourishing and whitening.
The technical scheme of the invention is realized by the following modes: the moisturizing, nourishing and whitening mask base solution comprises the following components in parts by weight:
0.2 to 0.4 portion of pearl hydrolysate
0.3-0.6 parts of ginseng extract
0.1-0.3 part of ligusticum wallichii extract
0.1 to 0.3 portion of vitamin E
15-20 parts of glycerol
Allantoin 0.1-0.3 part
4-6 parts of propylene glycol
0.02-0.03 part of zinc gluconate
0.002-0.003 part of tretinoin
60.1-0.3 parts of vitamin B
0.001-0.003 part of 2, 6-tert-butyl-p-cresol
Carbomer 9400.2-0.5 part
0.1 to 0.2 portion of ethylparaben
0.8-1 part of ethanol
0.1 to 0.5 portion of triethanolamine
74-80 parts of deionized water
The preparation method of the moisturizing, nourishing and whitening mask base solution comprises the following steps:
1) taking 0.2-0.5 part of carbomer 940 to swell in 50-70 parts of deionized water in the previous day, and fully swelling;
2) dissolving 0.002-0.003 part of tretinoin, 0.1-0.2 part of ethylparaben as preservative, 0.1-0.3 part of vitamin E and 0.001-0.003 part of 2, 6-tert-butyl-p-cresol in 0.8-1 part of ethanol to prepare ethanol mixed solution;
3) dissolving 0.2-0.4 part of pearl hydrolysate, 0.3-0.6 part of ginseng extract, 0.1-0.3 part of ligusticum wallichii extract, 15-20 parts of glycerol, 0.1-0.3 part of allantoin, 4-6 parts of propylene glycol, 0.02-0.03 part of zinc gluconate and 0.1-0.3 part of vitamin B6 in 10-24 parts of deionized water to prepare deionized water mixed solution;
4) adding the ethanol mixed solution in the step 2) and the deionized water mixed solution in the step 3) into the swelling solution of the carbomer 940 in the step 1), dropwise adding triethanolamine to adjust the pH value to 6.5-6.8, and injecting into the facial mask to obtain the facial mask.
The application of the moisturizing, nourishing and whitening mask base liquid in skin moisturizing, nourishing and whitening is characterized in that the prepared moisturizing, nourishing and whitening mask base liquid is lightly applied to the face, the mask base liquid is taken down after 15-20 minutes, the mask base liquid is washed by clean water after the skin absorbs a certain amount of moisture, the mask base liquid is continuously used for 3 days, one mask is used every day, 3 times a week later, the mask base liquid is continuously used for 4 weeks, and the thickness of the stratum corneum ~ basal layer of the facial skin is obviously larger than that of an unused mask and a commercially available common mask.
The skin-moistening cream is uniform, fine, appropriate in viscosity, easy to absorb and free of irritation to skin, can deeply nourish the skin after being applied for a long time, has an obvious moisturizing effect on the skin, increases the elasticity of the skin, and delays skin aging.
Drawings
Figure 1 is a histopathological structure diagram of facial skin from different treatment groups.
Detailed Description
Example 1:
1. swelling 0.4 part of carbomer 940 in 60 parts of deionized water in the previous day, and fully swelling;
2. dissolving 0.0025 part of tretinoin, 0.1 part of ethylparaben, 0.1 part of vitamin E and 0.002 part of 2, 6-tert-butyl-p-cresol in 1 part of ethanol to prepare ethanol mixed solution;
3. dissolving 0.3 part of pearl hydrolysate, 0.5 part of ginseng extract, 0.15 part of ligusticum wallichii extract, 20 parts of glycerol, 0.2 part of allantoin, 5 parts of propylene glycol, 0.025 part of zinc gluconate and 0.1 part of vitamin B6 in 15 parts of deionized water to prepare deionized water mixed solution;
4. and (3) adding the ethanol mixed solution in the step (2) and the deionized water mixed solution in the step (3) into the swelling solution of the carbomer 940 in the step (1), adjusting the pH value to be 6.5-6.8 by using triethanolamine, and injecting into the facial mask to obtain the facial mask.
Example 2:
1. swelling 0.3 part of carbomer 940 in 70 parts of deionized water in the previous day, and fully swelling;
2. dissolving 0.002 parts of tretinoin, 0.2 parts of ethylparaben, 0.3 parts of vitamin E and 0.003 part of 2, 6-tert-butyl-p-cresol in 0.8 part of ethanol to prepare an ethanol mixed solution;
3. dissolving 0.2 part of pearl hydrolysate, 0.4 part of ginseng extract, 0.2 part of ligusticum wallichii extract, 15 parts of glycerol, 0.25 part of allantoin, 4 parts of propylene glycol, 0.025 part of zinc gluconate and 0.2 part of vitamin B6 in 10 parts of deionized water to prepare deionized water mixed solution;
4. and (3) adding the ethanol mixed solution in the step (2) and the deionized water mixed solution in the step (3) into the swelling solution of the carbomer 940 in the step (1), adjusting the pH value to be 6.5-6.8 by using triethanolamine, and injecting into the facial mask to obtain the facial mask.
Example 3: thermal stability test
The moisturizing, nourishing and whitening mask base solution prepared in the example 1 is placed in a thermostat with the temperature of 55 ℃, and the prepared mask base solution keeps uniform and stable after 24 hours, has no layering phenomenon and good thermal stability.
Example 4: centrifugal experiment
The moisturizing, nourishing and whitening mask base solution prepared in the example 1 is placed in a centrifuge tube and centrifuged for 30 minutes at 3000 r/min, and the prepared mask base solution is uniform and stable without layering. Has better stability.
Example 5: moisturizing, nourishing and whitening facial mask base liquid effect experiment
The moisturizing, nourishing and whitening mask base liquid prepared in the example 1 is tried by volunteers to verify the moisturizing, nourishing and nourishing effects of the facial mask base liquid on the face, 90 tested volunteers are selected and evenly and randomly divided into 3 groups, a control group is that no mask is used and only normal skin care is carried out, an experimental group is that the moisturizing, nourishing and whitening mask base liquid prepared in the example 1 is used every day for 3 days and one piece of the moisturizing, nourishing and whitening mask base liquid is used every day for 3 times every day and is used for 4 weeks, a commercially available product group is that a commercially available moisturizing product is used every day, the use method is as the experimental group, 5 moisturizing products are randomly selected from each group of volunteers after 4 weeks, the influence of different products on the skin structure is examined by adopting the histopathology technology, as shown in figure 1, the result of histopathology slicing shows that the stratum corneum ~ basal layer thickness of the facial skin is obviously larger than the thicknesses of the unused mask and the commercially available ordinary mask, and the product can be used for deep nourishing the skin deeply and has obvious moisturizing effect on the skin, and can increase.
The invention comprises the following components:
the pearl hydrolysate, the ginseng extract and the ligusticum chuanxiong hort extract have the characteristics of antioxidation, anti-aging, skin microcirculation promotion and the like.
Allantoin: allantoin is an amphoteric compound, can combine with multiple substances to form a double salt, has the effects of protecting from light, sterilizing, preventing corrosion, relieving pain, resisting oxidation, and keeping skin moisture, moistening and softening. The face cream added with allantoin can make skin soft and elastic, and has beautiful luster, and can promote tissue growth, cell metabolism, soften stratum corneum protein, etc.
Vitamin E: is a fat-soluble vitamin. The hydrolysis product is tocopherol, which is one of the most important antioxidants. Effectively reduces the generation of wrinkles, protects cells of a body from being poisoned by free radicals, protects the skin from being damaged by ultraviolet rays and pollution, reduces the deposition of scars and pigments and keeps youthful appearance.
Glycerol: the cosmetic is colorless transparent viscous liquid, odorless, tasteless, hygroscopic, moisturizing, and softening, and can easily absorb water in air, and the water solution is neutral, has good antifreezing property, and can be used as solvent and softener for cosmetic.
Propylene glycol: a transparent, colorless, viscous and hygroscopic straight-chain fatty alcohol liquid, commonly used ointment, facial mask, cosmetic water, face lotion, essence, makeup remover, moisturizing lotion, plant extract, etc., can be used. Also commonly used in lotions and essences, in addition to moisturizing ability, can help penetration of active ingredients, and in addition, can help preservation ability; belongs to a small molecular moisture-retaining component and can retain moisture in the horny layer.
Tretinoin can permeate pores and remove blackheads; the zinc gluconate has the effect of regulating sebum secretion and regulating the water-oil balance of skin; vitamin B6 can promote amino acid metabolism; 2, 6-tert-butyl paracresol has an antioxidation effect, prevents vitamin components in the mask base solution from being damaged and oxidized, and ensures the effect; carbomer 940 is an anti-reflection agent, and can promote the base solution of the facial mask to be better contacted with the skin and promote absorption.
While the preferred embodiments of the present invention have been described in detail, it will be understood by those skilled in the art that the invention is not limited thereto, and that various changes and modifications may be made without departing from the spirit of the invention, and the scope of the appended claims is to be accorded the full range of equivalents.

Claims (3)

1. The moisturizing, nourishing and whitening mask base solution is characterized by comprising the following components in parts by weight: the components are as follows:
0.2 to 0.4 portion of pearl hydrolysate
0.3-0.6 parts of ginseng extract
0.1-0.3 part of ligusticum wallichii extract
0.1 to 0.3 portion of vitamin E
15-20 parts of glycerol
Allantoin 0.1-0.3 part
4-6 parts of propylene glycol
0.02-0.03 part of zinc gluconate
0.002-0.003 part of tretinoin
60.1-0.3 parts of vitamin B
0.001-0.003 part of 2, 6-tert-butyl-p-cresol
Carbomer 9400.2-0.5 part
0.1 to 0.2 portion of ethylparaben
0.8-1 part of ethanol
0.1 to 0.5 portion of triethanolamine
74-80 parts of deionized water
2. A method for preparing the moisturizing, nourishing and whitening mask base solution as set forth in claim 1, comprising the steps of:
1) taking 0.2-0.5 part of carbomer 940 to swell in a proper amount of deionized water in the previous day to prepare swelling deionized water;
2) dissolving 0.002-0.003 part of tretinoin, 0.1-0.2 part of ethylparaben as preservative, 0.1-0.3 part of vitamin E and 0.001-0.003 part of 2, 6-tert-butyl-p-cresol in 0.8-1 part of ethanol to prepare ethanol mixed solution;
3) dissolving 0.2-0.4 part of pearl hydrolysate, 0.3-0.6 part of ginseng extract, 0.1-0.3 part of ligusticum wallichii extract, 15-20 parts of glycerol, 0.1-0.3 part of allantoin, 4-6 parts of propylene glycol, 0.02-0.03 part of zinc gluconate and 0.1-0.3 part of vitamin B6 in 74-80 parts of deionized water to prepare deionized water mixed solution;
4) adding the ethanol mixed solution in the step 2) and the deionized water mixed solution in the step 3) into the swelling deionized water in the step 1), dropwise adding triethanolamine to adjust the pH value to 6.5-6.8, and injecting into a mask to obtain the composition.
3. The application of the moisturizing, nourishing and whitening mask base solution as claimed in claim 1 in skin moisturizing, nourishing and whitening is to lightly apply the moisturizing, nourishing and whitening mask base solution on the face, remove the base solution after 15-20 minutes, wash the skin after the skin absorbs a meeting, continuously use the facial mask for 3 days, one piece per day, 3 times per week and continuously use the facial mask for 4 weeks, wherein the thickness of the stratum corneum ~ base layer of the facial skin is obviously larger than that of the unused mask.
CN201810228352.0A 2018-03-20 2018-03-20 Moisturizing, nourishing and whitening mask base solution and preparation method thereof Active CN108261387B (en)

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CN108261387B true CN108261387B (en) 2019-12-20

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CN108653173A (en) * 2018-07-11 2018-10-16 江苏苏赋科技发展有限公司 A kind of whitening and spot eliminating cream and its preparation method and application

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106491497A (en) * 2016-11-26 2017-03-15 无锡市汉方八珍科技有限公司 A kind of for moisturizing, whitening, wrinkle resistant facial film base fluid

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106491497A (en) * 2016-11-26 2017-03-15 无锡市汉方八珍科技有限公司 A kind of for moisturizing, whitening, wrinkle resistant facial film base fluid

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