CN108192748A - A kind of impregnated wipe and preparation method thereof - Google Patents
A kind of impregnated wipe and preparation method thereof Download PDFInfo
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- CN108192748A CN108192748A CN201711458308.0A CN201711458308A CN108192748A CN 108192748 A CN108192748 A CN 108192748A CN 201711458308 A CN201711458308 A CN 201711458308A CN 108192748 A CN108192748 A CN 108192748A
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- benzalkonium chloride
- rough melic
- melic herb
- impregnated wipe
- herb extract
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/74—Carboxylates or sulfonates esters of polyoxyalkylene glycols
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47K—SANITARY EQUIPMENT NOT OTHERWISE PROVIDED FOR; TOILET ACCESSORIES
- A47K10/00—Body-drying implements; Toilet paper; Holders therefor
- A47K10/16—Paper towels; Toilet paper; Holders therefor
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/008—Polymeric surface-active agents
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/662—Carbohydrates or derivatives
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/72—Ethers of polyoxyalkylene glycols
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/825—Mixtures of compounds all of which are non-ionic
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2075—Carboxylic acids-salts thereof
- C11D3/2086—Hydroxy carboxylic acids-salts thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/26—Organic compounds containing nitrogen
- C11D3/30—Amines; Substituted amines ; Quaternized amines
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/26—Organic compounds containing nitrogen
- C11D3/33—Amino carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/382—Vegetable products, e.g. soya meal, wood flour, sawdust
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of impregnated wipe and preparation method thereof, containing weight percent benzalkonium chloride 0.01 0.10%, rough melic herb extract 0.5% 3.0%, surfactant 5%, disodium ethylene diamine tetraacetate 0.05%, synergist 0.01 1%, aloe extract 0.1%, citric acid 0.01 0.2% and deionized water surplus.The present invention is used with wide spectrum, efficient benzalkonium chloride as antiseptic, and pass through and add in the rough melic herb extract with special antibacterial effect, it effectively enhances the anti-microbial property of benzalkonium chloride under low concentration and makes up the antimicrobial spectrum for microorganisms such as Pseudomonas aeruginosas, formula is mild, alcohol-free ingredient, without phosphorus component, biodegradable, non-stimulated, corrosion-free, stability is good, cleaning simultaneously carries out disinfection to skin antibacterial, corner or spot as yet untouched by a clean-up campaign is eliminated, does not stay healthy hidden danger.
Description
Technical field
The present invention relates to daily-use chemical industry technical fields more particularly to a kind of impregnated wipe and preparation method thereof.
Background technology
With the raising that people's hygiene is realized, the simple wet tissue with cleaning function increasingly can not meet demand,
The wet tissue for having the function of cleaning and antibacterial etc. simultaneously is just gradually favored.
Benzalkonium chloride is the cationic surfactant of single-stranded quaternary ammonium salt, belongs to non-oxidative antimicrobial agent, has wide spectrum, height
The antibacterial algae removal ability of effect, at the same have it is certain deoil, deodorizing capability, be highly suitable for cleaning applications.Concentration 0.1%-
0.2% can change bacterial cytoplasm membrane permeability, make thalline endochylema extravasation, it is hindered to be metabolized and plays killing effect, to Glan
Positive bacteria effect is stronger but invalid to Pseudomonas aeruginosa, acid-fast bacilli and bacterial spore.
At present, the benzalkonium chloride thimerosal concentration used in the market is generally 0.1% hereinafter, but antibacterial at this concentration
Desirable is not achieved in effect, to meet disinfecting, antimicrobial requirement benzalkonium chloride disinfection liquid concentration should in 0.23-1%, however
When its liquid concentration is more than more than 0.13%, intense irritation can be generated to skin with the raising of liquid concentration.
Invention content
The technical problems to be solved by the invention be to provide it is a kind of can effectively cleaning sterilizing again will not be because of benzalkonium chloride
It is excessively used and stimulation is generated to skin, and there are other secondary impregnated wipe added.
In order to solve the above technical problems, the invention is realized by the following technical scheme：A kind of impregnated wipe contains weight hundred
Divide than benzalkonium chloride 0.01-0.1%, rough melic herb extract 0.5%-3.0%, surfactant 5%, disodium ethylene diamine tetraacetate
0.05%th, synergist 0.01-1%, aloe extract 0.1%, citric acid 0.01-0.2% and deionized water surplus.
Preferably, the benzalkonium chloride for alkyl side chain be respectively C12, C14 and C18 benzalkonium chloride mixture.
Preferably, the weight ratio of C12, C14 and C18 benzalkonium chloride is 1-3 in the mixture of the benzalkonium chloride:1-3:2-
5。
Preferably, the surfactant is fatty acid methyl ester ethoxylate, fatty alcohol polyoxyethylene ether, alkyl poly
Glucosides, any one or more in amide betaine type amphoteric surfactant.
Preferably, the synergist for Phenoxyethanol, Sensiva SC50,1,2- ethohexadiols, 1,2- pentanediols, 1,2- oneself
Any one or more in glycol, 14 glycol of 1,2-.
The impregnated wipe of the present invention also includes carrier, and the carrier is preferably hydro-entangled non-woven fabric.
The invention also includes the preparation methods of impregnated wipe：
1) rough melic herb extract, is prepared：It weighs rough melic herb and crushes sample, decoct 3h with the 7-8 times of water measured, filter, decompression
Relative density 1.15-1.2 at room temperature is concentrated into, is extracted with ethyl acetate, rough melic herb extract is made；
2) cleaning antimicrobial fluid, is prepared：
2.1) deionized water, surfactant, disodium ethylene diamine tetraacetate, synergist, reed, are added in vertical blending tank
Luxuriant growth extract, stirring is to being completely dissolved；
2.2), the benzalkonium chloride that alkyl side chain is respectively C12, C14 and C18 is sufficiently mixed, benzalkonium chloride is made
Mixture；
2.3) benzalkonium chloride mixture, rough melic herb extract, are added in into vertical blending tank, stirring is to being completely dissolved；
2.4) citric acid, is added in while stirring, between adjusting pH5-5.5, is made；
3) wet tissue, is prepared：The non-woven fabrics after cutting, sterilizing is taken to be impregnated with above-mentioned cleaning antimicrobial fluid, sealed, sterile packaging, i.e.,
.
The rough melic herb that the present invention uses be grass family Dimeria herbaceos perennial also known as timothy grass, Herba pogonatheri criniti, gold
Contain the compounds such as flavonoids, phenolic acid class and steroid in silk grass.Wherein flavones and its glycosides compound are in antimycotic, antibacterium
And anti-nematode etc. shows certain activity.The polysaccharide in the rough melic herb of surface is studied to superoxide anion and hydroxyl free
Base have good Scavenging activity, for pathology or ultraviolet light irradiation under due to OH free radicals increase, and caused by skin glue
Fibrinogen and elastomer etc. are followed the string and are broken and wrinkle occur, and generation melanin and generation color spot etc. have good change
Kind effect.
Beneficial effects of the present invention：, as antiseptic, pass through alkyl side chain point using with wide spectrum, efficient benzalkonium chloride
Not Wei C12, C14 and C18 benzalkonium chloride reasonable compounding, maximize the intermolecular mutual synergistic effect of different quaternary ammonium salts,
It enhances and thalline is adsorbed, and then accelerate the rate of cleavage of thalline, a kind of obtained antibacterial effect preferably prick by compound benzene
Oronain.The rough melic herb extract with special antibacterial effect additionally incorporated effectively enhances the anti-of benzalkonium chloride under low concentration
Bacterium performance and make up the antimicrobial spectrum for microorganisms such as Pseudomonas aeruginosas, formula is mild, and alcohol-free ingredient, no phosphorus component, biology can
Degradation, non-stimulated, corrosion-free, stability is good, cleaning simultaneously carries out disinfection to skin antibacterial, eliminates corner or spot as yet untouched by a clean-up campaign, does not stay health
Hidden danger.
Specific embodiment
The specific embodiment of the present invention is exemplified below：
Embodiment 1
1) rough melic herb extract, is prepared：It weighs rough melic herb and crushes sample, decoct 3h with the 7-8 times of water measured, filter, decompression
Relative density 1.15-1.2 at room temperature is concentrated into, is extracted with ethyl acetate, rough melic herb extract is made；
2) cleaning antimicrobial fluid, is prepared：
2.1) deionized water 92.72%, fatty acid methyl ester ethoxylate 2%, fatty alcohol, are added in vertical blending tank
Polyoxyethylene ether 3%, disodium ethylene diamine tetraacetate 0.05%, Phenoxyethanol 0.05%, aloe extract 0.1%, are stirred to complete
Fully dissolved；
2.2), the benzalkonium chloride that alkyl side chain is respectively C12, C14 and C18 is sufficiently mixed, benzalkonium chloride is made
Mixture, the wherein weight ratio of C12, C14 and C18 benzalkonium chloride are 1:1:3；
2.3) benzalkonium chloride mixture 0.05%, rough melic herb extract 2%, are added in into vertical blending tank, is stirred to complete
Fully dissolved；
2.4) citric acid 0.03%, is added in while stirring, between adjusting pH5-5.5, is made；
3) wet tissue, is prepared：The non-woven fabrics after cutting, sterilizing is taken to be impregnated with above-mentioned cleaning antimicrobial fluid, sealed, sterile packaging, i.e.,
.
Embodiment 2
1) rough melic herb extract, is prepared：It weighs rough melic herb and crushes sample, decoct 3h with the 7-8 times of water measured, filter, decompression
Relative density 1.15-1.2 at room temperature is concentrated into, is extracted with ethyl acetate, rough melic herb extract is made；
2) cleaning antimicrobial fluid, is prepared：
2.1) deionized water 94.31%, fatty alcohol polyoxyethylene ether 5%, ethylenediamine tetrem, are added in vertical blending tank
Acid disodium 0.05%, ethylhexyl glycerine 0.06%, aloe extract 0.1%, stirring is to being completely dissolved；
2.2), the benzalkonium chloride that alkyl side chain is respectively C12, C14 and C18 is sufficiently mixed, benzalkonium chloride is made
Mixture, the wherein weight ratio of C12, C14 and C18 benzalkonium chloride are 2:1:5；
2.3) benzalkonium chloride mixture 0.05%, rough melic herb extract 0.5%, are added in into vertical blending tank, stirring is extremely
It is completely dissolved；
2.4) citric acid 0.03%, is added in while stirring, between adjusting pH5-5.5, is made；
3) wet tissue, is prepared：The non-woven fabrics after cutting, sterilizing is taken to be impregnated with above-mentioned cleaning antimicrobial fluid, sealed, sterile packaging, i.e.,
.
Embodiment 3
1) rough melic herb extract, is prepared：It weighs rough melic herb and crushes sample, decoct 3h with the 7-8 times of water measured, filter, decompression
Relative density 1.15-1.2 at room temperature is concentrated into, is extracted with ethyl acetate, rough melic herb extract is made；
2) cleaning antimicrobial fluid, is prepared：
2.1) deionized water 92.69%, alkyglycosides 5%, ethylenediamine tetra-acetic acid two, are added in vertical blending tank
Sodium 0.05%, 1,2- ethohexadiols 0.03%, aloe extract 0.1%, stirring is to being completely dissolved；
2.2), the benzalkonium chloride that alkyl side chain is respectively C12, C14 and C18 is sufficiently mixed, benzalkonium chloride is made
Mixture, the wherein weight ratio of C12, C14 and C18 benzalkonium chloride are 1:2:5；
2.3) benzalkonium chloride mixture 0.06%, rough melic herb extract 2%, are added in into vertical blending tank, is stirred to complete
Fully dissolved；
2.4) citric acid 0.07%, is added in while stirring, between adjusting pH5-5.5, is made；
3) wet tissue, is prepared：The non-woven fabrics after cutting, sterilizing is taken to be impregnated with above-mentioned cleaning antimicrobial fluid, sealed, sterile packaging, i.e.,
.
Embodiment 4
1) rough melic herb extract, is prepared：It weighs rough melic herb and crushes sample, decoct 3h with the 7-8 times of water measured, filter, decompression
Relative density 1.15-1.2 at room temperature is concentrated into, is extracted with ethyl acetate, rough melic herb extract is made；
2) cleaning antimicrobial fluid, is prepared：
2.1) deionized water 91.6%, fatty acid methyl ester ethoxylate 5%, ethylenediamine, are added in vertical blending tank
Tetraacethyl disodium 0.05%, 1,2- pentanediols 0.03%, aloe extract 0.1%, stirring is to being completely dissolved；
2.2), the benzalkonium chloride that alkyl side chain is respectively C12, C14 and C18 is sufficiently mixed, benzalkonium chloride is made
Mixture, the wherein weight ratio of C12, C14 and C18 benzalkonium chloride are 1:2:5；
2.3) benzalkonium chloride mixture 0.1%, rough melic herb extract 3%, are added in into vertical blending tank, is stirred to complete
Dissolving；
2.4) citric acid 0.12%, is added in while stirring, between adjusting pH5-5.5, is made；
3) wet tissue, is prepared：The non-woven fabrics after cutting, sterilizing is taken to be impregnated with above-mentioned cleaning antimicrobial fluid, sealed, sterile packaging, i.e.,
.
Comparative example 1
1) cleaning antimicrobial fluid, is prepared：
1.1) deionized water 94.61%, fatty acid methyl ester ethoxylate 5%, ethylenediamine, are added in vertical blending tank
Tetraacethyl disodium 0.05%, 1,2- pentanediols 0.03%, aloe extract 0.1%, stirring is to being completely dissolved；
1.2), the benzalkonium chloride that alkyl side chain is respectively C12, C14 and C18 is sufficiently mixed, benzalkonium chloride is made
Mixture, the wherein weight ratio of C12, C14 and C18 benzalkonium chloride are 1:2:5；
1.3) benzalkonium chloride mixture 0.1%, is added in into vertical blending tank, stirring is to being completely dissolved；
1.4) citric acid 0.11%, is added in while stirring, between adjusting pH5-5.5, is made；
2) wet tissue, is prepared：The non-woven fabrics after cutting, sterilizing is taken to be impregnated with above-mentioned cleaning antimicrobial fluid, sealed, sterile packaging, i.e.,
.
Comparative example 2
1) rough melic herb extract, is prepared：It weighs rough melic herb and crushes sample, decoct 3h with the 7-8 times of water measured, filter, decompression
Relative density 1.15-1.2 at room temperature is concentrated into, is extracted with ethyl acetate, rough melic herb extract is made；
2) cleaning antimicrobial fluid, is prepared：
2.1) deionized water 91.72%, fatty acid methyl ester ethoxylate 5%, ethylenediamine, are added in vertical blending tank
Tetraacethyl disodium 0.05%, 1,2- pentanediols 0.03%, aloe extract 0.1%, stirring is to being completely dissolved；
2.2) rough melic herb extract 3%, is added in into vertical blending tank, stirring is to being completely dissolved；
2.3) citric acid 0.10%, is added in while stirring, between adjusting pH5-5.5, is made；
3) wet tissue, is prepared：The non-woven fabrics after cutting, sterilizing is taken to be impregnated with above-mentioned cleaning antimicrobial fluid, sealed, sterile packaging, i.e.,
.
Comparative example 3
1) cleaning antimicrobial fluid, is prepared：
1.1) deionized water 94.7%, fatty acid methyl ester ethoxylate 5%, ethylenediamine, are added in vertical blending tank
Tetraacethyl disodium 0.05%, 1,2- pentanediols 0.03%, aloe extract 0.1%, stirring is to being completely dissolved；
1.2) citric acid 0.12%, is added in while stirring, between adjusting pH5-5.5, is made；
2) wet tissue, is prepared：The non-woven fabrics after cutting, sterilizing is taken to be impregnated with above-mentioned cleaning antimicrobial fluid, sealed, sterile packaging, i.e.,
.
In order to verify the antibacterial effect of benzalkonium chloride and rough melic herb extract, applicant has also done following experiment：
For trying strain
Escherichia coli (CMCC (B) 44103), staphylococcus aureus (CMCC (B) 26003), Pseudomonas aeruginosa (CMCC
10104), saccharomycete：Candida albicans (CMCC (F) 98001).
It is prepared by culture medium
Different culture mediums is prepared according to different microorganism fungus kinds.Nutrient agar：Take a certain amount of peptone,
After beef extract, sodium chloride and distilled water mixed dissolution, pH to 7.2~7.4 is adjusted, adds in agar, dissolves by heating and is steamed in 121 DEG C of pressure
Vapour sterilizing 20min, is cultivated for Escherichia coli, staphylococcus aureus, Pseudomonas aeruginosa.Sabouraud's agar：It takes a certain amount of
Glucose, peptone, agar and distilled water mixing after, be heated to being completely dissolved, adjust pH to 5.6 ± 0.2, in 115 DEG C of pressure
Steam sterilizing 30min, for Candida albicans culture.
It is prepared by bacteria suspension
Taking test organisms, slant culture is washed down with 5mL0.03mol/L phosphate buffers (hereinafter referred to as PBS) for 24 hours, with
Above-mentioned PBS is diluted to required concentration, be made bacteria suspension (it is required that it is a concentration of：With 100 μ L drops in 5mL sample liquids, bacterial count recovered is
1×104~9 × 104cfu/mL)。
Antibacterial tests
It takes and (with sample homogeneous material, equal size, but without anti-biotic material, and is passed through by test liquid (5mL) and control sample liquid
Sterilization treatment) it is each 5 pipe.Above-mentioned bacteria suspension is taken, 100 μ L are added dropwise in test liquid and control sample liquid each respectively, with electronic mixed
Clutch is uniformly mixed, and starts timing, effect 2,5,10,20min, respectively by sample liquid (0.5mL) input corresponding neutralizer containing 5mL
In test tube, abundant mixing makees appropriate dilution, then takes wherein 2~3 dilutions, draw 0.5mL respectively, be placed in two plates,
It is poured into cool to 40~45 DEG C of nutrient agars (bacterium) or sabouraud's agar (saccharomycete) 15mL, rotation is flat
Ware makes its full and uniform, and tablet, 35 DEG C of ± 2 DEG C of culture 48h (bacterium) or 72h (saccharomycete) are overturn after agar solidification, makees viable bacteria
Bacterium colony counts.Experiment is repeated 3 times, and is averaged.
Antibacterial efficacy judges
After cultivating 48h or 72h, antibiotic rate is calculated as follows：X=(A-B)/A × 100%.In formula：X is antibiotic rate,
A is control sample average colony number, and B is subject sample average clump count.Evaluation criterion：Antibiotic rate >=90%, product have antibacterial
Effect.
Antibacterial test more than carries out antibacterial tests to the present embodiment 1-4 and comparative example 1-3 respectively,
Finally using the microorganism concn and the percentage of the initial concentration of microorganism do not survived as basis for estimation, the cleaning of the present invention is judged
The antibacterial efficacy of wet tissue.
The antibacterial efficacy of the impregnated wipe of embodiment 1-4 and comparative example 1-3 is as shown in the table：
Although the present invention is shown and described with reference to several preferred embodiments therein, this above are only
Several specific embodiments of invention, but the design concept of the present invention is not limited thereto, and is not departing from spirit of the invention and model
In the case of enclosing various changes, deletion and increase can be carried out to its form and details.It is but it should be noted that more possible
Modification is still fallen in scope of the claims.
Claims (7)
1. a kind of impregnated wipe, it is characterised in that：Contain weight percent benzalkonium chloride 0.01-0.1%, rough melic herb extract
0.5%-3.0%, surfactant 5%, disodium ethylene diamine tetraacetate 0.05%, synergist 0.01-1%, aloe extract 0.1%, lemon
Lemon acid 0.01-0.2% and deionized water surplus.
2. impregnated wipe according to claim 1, which is characterized in that the benzalkonium chloride for alkyl side chain be respectively C12,
The mixture of the benzalkonium chloride of C14 and C18.
3. impregnated wipe according to claim 2, which is characterized in that in the mixture of the benzalkonium chloride C12, C14 and
The weight ratio of C18 benzalkonium chlorides is 1-3:1-3:2-5.
4. impregnated wipe according to claim 1, which is characterized in that the surfactant is fatty acid methyl ester ethyoxyl
Compound, fatty alcohol polyoxyethylene ether, alkyglycosides, in amide betaine type amphoteric surfactant any one or it is more
Kind.
5. impregnated wipe according to claim 1, which is characterized in that the synergist is Phenoxyethanol, ethylhexyl is sweet
Any one or more in oil, 1,2- ethohexadiols, 1,2- pentanediols, 1,2- hexylene glycols, 1,2-, 14 glycol.
6. impregnated wipe according to claim 1, which is characterized in that further included carrier, the carrier, which is that spun lacing is non-, to be knitted
Make cloth.
7. the preparation method of claim 1-6 any one of them impregnated wipe, includes the following steps：
1）, prepare rough melic herb extract：It weighs rough melic herb and crushes sample, decoct 3h with the 7-8 times of water measured, filter, be concentrated under reduced pressure
It to relative density 1.15-1.2 at room temperature, is extracted with ethyl acetate, rough melic herb extract is made；
2）, prepare cleaning antimicrobial fluid：
2.1）, add in vertical blending tank deionized water, surfactant, disodium ethylene diamine tetraacetate, synergist, aloe carry
Take object, stirring is to being completely dissolved；
2.2）, be respectively that the benzalkonium chloride of C12, C14 and C18 is sufficiently mixed by alkyl side chain, benzalkonium chloride mixing is made
Object；
2.3）, add in benzalkonium chloride mixture, rough melic herb extract into vertical blending tank, stirring is to being completely dissolved；
2.4）, add in citric acid while stirring, between adjusting pH5-5.5, be made；
3）, prepare wet tissue：Take cutting, sterilizing after non-woven fabrics impregnated with above-mentioned cleaning antimicrobial fluid, sealed, sterile pack to get.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711458308.0A CN108192748A (en) | 2017-12-28 | 2017-12-28 | A kind of impregnated wipe and preparation method thereof |
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| CN201711458308.0A CN108192748A (en) | 2017-12-28 | 2017-12-28 | A kind of impregnated wipe and preparation method thereof |
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| CN108192748A true CN108192748A (en) | 2018-06-22 |
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| CN201711458308.0A Pending CN108192748A (en) | 2017-12-28 | 2017-12-28 | A kind of impregnated wipe and preparation method thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2689373A1 (en) * | 2018-09-25 | 2018-11-13 | Euro-Goodnight S.L. | WET AND REFRESHING TOWEL (Machine-translation by Google Translate, not legally binding) |
| CN110585031A (en) * | 2019-10-18 | 2019-12-20 | 海安康瑞纺织品有限公司 | Wet tissue for cleaning, removing sweat and disinfecting skin after exercise and preparation method thereof |
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Cited By (13)
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| ES2689373A1 (en) * | 2018-09-25 | 2018-11-13 | Euro-Goodnight S.L. | WET AND REFRESHING TOWEL (Machine-translation by Google Translate, not legally binding) |
| WO2020065105A1 (en) * | 2018-09-25 | 2020-04-02 | Euro-Goodnight, S.L. | Wet and refreshing wipe |
| CN110585031A (en) * | 2019-10-18 | 2019-12-20 | 海安康瑞纺织品有限公司 | Wet tissue for cleaning, removing sweat and disinfecting skin after exercise and preparation method thereof |
| CN111073771A (en) * | 2019-12-06 | 2020-04-28 | 李斌 | Mosquito-removing cleaning and maintaining wet tissue for waterless car washing |
| WO2021116092A1 (en) * | 2019-12-10 | 2021-06-17 | Gama Healthcare Ltd | Universal formulation |
| GB2603446A (en) * | 2019-12-10 | 2022-08-03 | Gama Healthcare Ltd | Universal formulation |
| CN115103592A (en) * | 2019-12-10 | 2022-09-23 | 伽马保健有限公司 | Universal formulation |
| GB2603446B (en) * | 2019-12-10 | 2024-07-24 | Gama Healthcare Ltd | Disinfectant composition |
| CN111214157A (en) * | 2020-01-10 | 2020-06-02 | 河南润禾新材料有限公司 | Wormwood sterilizing wet tissue and preparation method thereof |
| WO2022002607A1 (en) * | 2020-07-03 | 2022-01-06 | Unilever Ip Holdings B.V. | Composition |
| CN115735002A (en) * | 2020-07-03 | 2023-03-03 | 联合利华知识产权控股有限公司 | Composition comprising a metal oxide and a metal oxide |
| CN111840182A (en) * | 2020-07-27 | 2020-10-30 | 支允前 | Multifunctional traditional Chinese medicine antibacterial sanitary wet tissue and preparation method thereof |
| CN113527529A (en) * | 2021-07-29 | 2021-10-22 | 华侨大学 | Aleuritopteris argentea fee polysaccharide and preparation method and application thereof |
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Application publication date: 20180622 |