CN108126040A - A kind of preparation method of the traditional Chinese medicine reagent for preventing eczema, washing lotion and ointment - Google Patents
A kind of preparation method of the traditional Chinese medicine reagent for preventing eczema, washing lotion and ointment Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Abstract
The present invention provides the preparation methods of a kind of traditional Chinese medicine reagent for preventing eczema, washing lotion and ointment, are related to the field of Chinese medicines.The traditional Chinese medicine reagent includes 10~20 parts of litharge, 1~10 part of realgar, 5~15 parts of frutus cnidii, 5~15 parts of Cortex Phellodendri, 1~8 part of the fruit of summer cypress, 5~15 parts of borneol, 1~6 part of Chinese gall, 4~12 parts of the root bark of shaggy-fruited dittany, 4~7 parts of Radix Salviae Miltiorrhizae, 7~14 parts of felwort and 5~15 parts of kuh-seng.It extracts 3~4h after being mixed with alcoholic solution at 60~62 DEG C at 98~100 DEG C, and then washing lotion can be prepared in concentration at 85~90 DEG C.Meanwhile can also be after concentration extraction with 5~8 parts stearic acid, 1~3 part of atoleine, 1~4 part of wool grease be mixed to prepare ointment.The characteristics of this washing lotion or ointment can effectively prevent eczema, have good effect for the eczema having occurred and that, treatment cycle is short, has larger market popularization value.
Description
Technical field
The present invention relates to the field of Chinese medicines, and the preparation of more particularly to a kind of traditional Chinese medicine reagent for preventing eczema, washing lotion and ointment
Method.
Background technology
Eczematosis is common disease, frequently-occurring disease, such as erythema, red pimple, acute pruritus, water sore, sepage, yellow water it is dripping, it is rotten to the corn,
Incrustation, infiltration and chap etc..Eczema includes infantile eczema, exudative type eczema, drying type eczema, childhood eczema, eczema mammae, the moon
Capsule eczema, pudendum eczema, eczema of anus, hand eczema, leg foot eczema, eczema fissum etc..Eczema is that one kind has significantly
The allergic inflammatory cutaneous lesions of tendency are oozed out, are a kind of common skin disorders of dept. of dermatology.Eczema has on incidence in recent years
Rise trend, this may with chemicals extensives application, environmental pollution, rhythm of life quickening etc. factors it is related.Eczema is in having
A kind of delayed allergy, related with genetic constitution caused by outer motivating factor, so only occur in specific crowd, but
Whether morbidity, but by environment, thereafter, whole body health situation influenced.
There is a variety of drugs for eczematosis on the market, but long there are treatment cycle, the problems such as curative effect is poor, these
Problem seriously annoyings eczema patient.
Invention content
The purpose of the present invention is to provide a kind of traditional Chinese medicine reagent for preventing eczema, this traditional Chinese medicine reagent on the one hand can be effectively
Prevent eczema, on the other hand there is good effect for the eczema that has occurred and that, the characteristics for the treatment of cycle is short, have larger
Market popularization value.
Second object of the present invention is to provide a kind of preparation method for the washing lotion for preventing eczema, the letter of this preparation method
It is single, convenient, the active ingredient of each raw material can be efficiently extracted, so as to improve the validity of medicament.The washing lotion being prepared
On the one hand it can effectively prevent eczema, on the other hand there is good effect for the eczema having occurred and that, treatment cycle is short
The characteristics of, there is larger market popularization value.
Third object of the present invention is to provide a kind of preparation method for the ointment for preventing eczema, the letter of this preparation method
It is single, convenient, the active ingredient of each raw material can be efficiently extracted, so as to improve the validity of medicament.The ointment being prepared
On the one hand it can effectively prevent eczema, on the other hand there is good effect for the eczema having occurred and that, treatment cycle is short
The characteristics of, there is larger market popularization value.
The present invention is solved its technical problem and is realized using following technical scheme.
The present invention proposes a kind of traditional Chinese medicine reagent for preventing eczema, prevents the traditional Chinese medicine reagent of eczema mainly by following parts by weight
Raw material be made：
10~20 parts of litharge, 1~10 part of realgar, 5~15 parts of frutus cnidii, 5~15 parts of Cortex Phellodendri, 1~8 part
The fruit of summer cypress, 5~15 parts of borneol, 1~6 part of Chinese gall, 4~12 parts of the root bark of shaggy-fruited dittany, 4~7 parts of Radix Salviae Miltiorrhizae, 7~14 parts of dragon
Courage grass and 5~15 parts of kuh-seng.
The present invention proposes a kind of preparation method for the washing lotion for preventing eczema, including：
Mixing step：By in the Chinese medicine preparation for preventing eczema litharge, realgar, frutus cnidii, Cortex Phellodendri, the fruit of summer cypress, borneol,
Chinese gall, the root bark of shaggy-fruited dittany, Radix Salviae Miltiorrhizae, felwort and kuh-seng are uniformly mixed at a temperature of 60~62 DEG C, form the first mixture；
Extraction step：First mixture and alcoholic solution are mixed to form the second mixture, and by the second mixture 98~
Filtrate is obtained by filtration after 3~4h of tanning for the first time is carried out at a temperature of 100 DEG C；
Concentrate pharmaceutical procedures：Filtrate is concentrated into 1000mL at a temperature of 85~90 DEG C and obtains the washing lotion of prevention eczema.
The present invention also provides it is a kind of prevent eczema ointment preparation method, including：
Mixing step：By in the Chinese medicine preparation for preventing eczema litharge, realgar, frutus cnidii, Cortex Phellodendri, the fruit of summer cypress, borneol,
Chinese gall, the root bark of shaggy-fruited dittany, Radix Salviae Miltiorrhizae, felwort and kuh-seng are uniformly mixed at a temperature of 60~62 DEG C, form third mixture；
Extract concentration step：It is filtered after third mixture and alcoholic solution are extracted 3~4h at a temperature of 98~100 DEG C
To extracting solution, by extracting solution according to 20~30:1 ratio is concentrated into 1000mL and obtains the 4th mixture；
Heating and melting step：By in parts by weight 5~8 parts of stearic acid, 1~3 part of atoleine, 1~4 part
Wool grease mixing, and be heated to fusing after obtain the 5th mixture；
Cream step processed：The ointment of prevention eczema is made after 4th mixture is mixed with the 5th mixture.
The advantageous effect of the preparation method of the traditional Chinese medicine reagent of the prevention eczema of the embodiment of the present invention, washing lotion and ointment is：
The traditional Chinese medicine reagent of the prevention eczema of offer include rational proportion after litharge, realgar, frutus cnidii, Cortex Phellodendri, summer cypress
On the one hand son, borneol, Chinese gall, the root bark of shaggy-fruited dittany, Radix Salviae Miltiorrhizae, felwort and kuh-seng can effectively prevent eczema, the opposing party
The characteristics of facing the eczema having occurred and that has good effect, and treatment cycle is short, has larger market popularization value.
The washing lotion of the prevention eczema of offer and the preparation method simple possible of ointment, it is highly practical, in original technique base
Improvement on plinth so that the drug effect of each raw material is effectively played.So that the traditional Chinese medicine reagent being prepared on the one hand can
Effectively to prevent eczema, on the other hand there is good effect for the eczema that has occurred and that, the characteristics for the treatment of cycle is short, tool
There is larger market popularization value.
Specific embodiment
Purpose, technical scheme and advantage to make the embodiment of the present invention are clearer, below will be in the embodiment of the present invention
Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, builds according to normal condition or manufacturer
The condition of view carries out.Reagents or instruments used without specified manufacturer is the conventional production that can be obtained by commercially available purchase
Product.
Traditional Chinese medicine reagent, washing lotion and the ointment of a kind of prevention eczema of the embodiment of the present invention are specifically described below.
A kind of traditional Chinese medicine reagent for preventing eczema, prevents the traditional Chinese medicine reagent of eczema mainly by the raw material system of following parts by weight
Into：
10~20 parts of litharge, 1~10 part of realgar, 5~15 parts of frutus cnidii, 5~15 parts of Cortex Phellodendri, 1~8 part
The fruit of summer cypress, 5~15 parts of borneol, 1~6 part of Chinese gall, 4~12 parts of the root bark of shaggy-fruited dittany, 4~7 parts of Radix Salviae Miltiorrhizae, 7~14 parts of dragon
Courage grass and 5~15 parts of kuh-seng.Litharge, realgar, frutus cnidii, Cortex Phellodendri, the fruit of summer cypress, borneol, Chinese gall after rational proportion,
On the one hand the root bark of shaggy-fruited dittany, Radix Salviae Miltiorrhizae, felwort and kuh-seng can effectively prevent eczema, on the other hand for having occurred and that
The characteristics of eczema has good effect, and treatment cycle is short has larger market popularization value.
In detail, a kind of solid drier containing lead oxide of litharge (Lithargyrum) enters oil and plays the dry work of promotion
With.It is the oxide mineral of lead, it takes on a red color, and belongs to tetragonal crystal system, very heavy also very soft, there is greasy luster.Originate in the oxygen of lead deposit
Change area.The oxide mineral of lead also has one kind to be lead and yellow-collation, in yellow, belongs to rhombic system.
Litharge cures mainly pyogenic infections sore disease, aphthae, eczema wet sore, bacillary dysentery diarrhea and body odour, detumescence desinsection, and convergence is prevented
Corruption, promoting expectoration to arrest convulsion.Control hemorrhoid, pyogenic infections, ulcer, eczema, body odour, wound, protracted dysentery, frightened epilepsy.
In detail, realgar, α-As4S4 are also referred to as orpiment, gold stone, realgar, are the ores of a kind of sulfur-bearing and arsenic, matter
Soft, property is crisp, usually granular, close shape block or powder, and streak is in shallow salmon pink.Realgar mainly originates in epithermal deposit
In, often with orpiment (As2S3), stibnite, cinnabar symbiosis；Originate in the hero of deposit in warm spring sediment and sulphur matter volcanic fumarole
Huang, then often with orpiment symbiosis.Not soluble in water and hydrochloric acid, dissolves in nitric acid, and solution is in yellow.
Realgar can detoxify desinsection, removing dampness and eliminating phlegm, preventing malaria.For carbuncle swells furunculosis, snakebite and bugbite, abdominal pain due to enterositosis, frightened epilepsy, malaria
Disease.
In detail, frutus cnidii alias cicely is the dry mature fruit of samphire cnidium monnieri.Summer, two season of autumn fruit
It is harvested when real ripe, removes impurity, dry.Nature and flavor：It is warm-natured, bitter.Major function：Warming kidney and enhancing body, eliminating dampness, wind-dispelling, desinsection.With
In impotence, Gong Leng, morbid leucorrhoea duye, arthritis with fixed pain caused by dampness pain in the back；Control eczema of vulva, married woman's pruritus vulvae, trichomonas vaginitis outside.
In detail, Cortex Phellodendri is Rutaceae Phellodendron deciduous tree, and bark taupe to black gray expandable, phellem layer is flourishing, soft,
Endothelium foresythia；Sprig is orange-yellow or yellowish grey, naked bub are born in leaf scar, yellowish-brown, imparipinnate leaf, to it is raw or it is near mutually
It is raw；Flower unisexuality, dioecism, sympodium panicle basidixed；Spend small, yellow green, petal oblong, ovary falls oval, slurry
Fruit shape drupe is subsphaeroidal, and black when ripe has special aroma and bitter taste；Seed semioval shape, band black.
Cortex Phellodendri bitter, it is cold in nature.It is clearing heat and detoxicating, purging intense heat eliminating dampness.Cure mainly acute bacillary dysentery, chordapsus, acute jaundice
The inflammation such as type hepatitis, urinary system infection contamination.Burning hot wound, tympanitis, acute conjunctivitis etc. are controlled in external application.
In detail, the fruit of summer cypress is in oblate spheroid shape pentalpha, 1~3mm of diameter.It is outer by persitent perianth, surface celadon or shallow
Brown, surrounding have 5 pieces of film quality winglet, and there are the dotted carpopodium trace of micro-protuberance and radial vein 5~10 in north center；Stripping flower
Quilt, it is seen that film quality pericarp is translucent.Seed is flat avette, is about 1mm, black.Gas is micro-, mildly bitter flavor.
The fruit of summer cypress has the effect of clearing heat and promoting diuresis, dispelling wind and arresting itching.Available under difficulty and pain in micturition, pruritus vulvae band, rubella, eczema,
Pruitus.
In detail, borneol is the crystallization obtained from the resin and volatile oil of kapur, is almost pure d-Bomeol.
Ter penoids there are many containing in the resin and volatile oil of kapur.In addition to borneol, still containing Humuleno, beta-elemene, carypohyllene etc.
Sequiterpene, the triterpene compounds such as oleanolic acid, alphitolic acid, asiatic acid, dipterocarpol, dryobalanone, erythrodiol
Object.
Borneol can lead to all keys, dissipate stagnated fire, remove screen improving eyesight, swelling and pain relieving.Control apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm confusing heart, gas
Close deafness, larynx numbness, aphtha, tympanitis, carbuncle swells, hemorrhoid, mesh also screen film, enterobiasis.
In detail, Chinese gall also known as hundred worm storehouses, fermented Chinese gall herb and tea leaves, gall are that horned gall aphid or the melaphis peitan Tsai et Tang of Homoptera aphid section are female
Worm parasitizes Anacardiaceae plant " Chinese sumac " and its belongs to the tender leaf or petiole of other plant, stabs and generates a kind of cryptomere consor
Object insect gall, the gained after drying times drying.In addition, Chinese gall or a kind of medicinal material, can treat a variety of diseases.
Chinese gall meridian distribution of property and flavor：It is sour, it is puckery, it is cold in nature.Return lung, large intestine, kidney channel.Effect：It astringes the lung；Hidroschesis；Puckery intestines；Controlling nocturnal emission with astringent drugs；
Hemostasis；Removing toxic substances.It cures mainly：Chronic cough of deficiency lung；Spontaneous sweating；Protracted dysentery chronic diarrhea；Rectal prolapse；Seminal emission；Gonorrhoea；Various bleedings；Carbuncle swells boil.Together
When Schisandra chinensis have tannic acid general pharmacological action, can make the part such as skin, mucous membrane, ulcer tissue protein solidify and rise receipts
The effect of holding back can accelerate blood clotting and have anastalsis；Alkaloid can be precipitated and have solution alkaloid intoxication.Also, five times
Sub- decoction has inhibiting effect to staphylococcus aureus, bacterium flexneri, hog cholera bacillus and Escherichia coli.Through with ether
It is proposed that it is rubbed the Chinese gall liquid after acid and still has an antibacterial action, the ingredient of antibacterial action is primarily present in skin zone, and center portion is boiled
Liquid is then without antibacterial action.
In detail, the root bark of shaggy-fruited dittany is Rutaceae herbaceos perennial shaggy-fruited dittany and the root skin of Dictamnus angustifolius.Main product is in Liaoning, river
The ground such as north, Sichuan, Jiangsu.Spring, two season of autumn excavation root, remove silt and tertia, strip root skin, be sliced, dry.It is raw to use.Tool
There is the effect of heat-clearing and damp-drying drug, wind-dispelling is detoxified.
In detail, Radix Salviae Miltiorrhizae is dicotyledon Lamiaceae Salvia category perennial vertical herbage plant, and root fertilizer is thick, outer bright red
Color, interior white, meat, leaf are often imparipinnate leaf, basidixed or axillary-racemes；Bract lanceolar, calyx is bell, and band is purple
Color, corolla hyacinthine, style far ultraviolet are stretched, pyrene black, and ellipse blooms, sees fruit after spending the 4-8 months.This kind of root is used as medicine, containing pellet
Join ketone, be robustness emmenagogue, there are the effectiveness such as dissolving stasis, raw new, promoting blood circulation, menstruation regulating, be gynaecology's key medicine, cure mainly uterine hemorrhage, menstruation
It is uncomfortable, blood stasis, abdominal pain, dysmenorrhoea, Amenorrhea, mausoleum pain.There is good result to treatment coronary heart disease.In addition the weak insomnia of nerve is also controlled,
Arthralgia, anaemia, mastitis, adenolymphitis, arthritis, boil pain is swollen, erysipelas, acute, chronic hepatitis, kidney Meng, ephritis, bruise damage
Wound, advanced schistosomiasis hepatosplenomegaly , Dian Epilepsy.External application can wash dermatitis rhus again.
In detail, felwort root and rhizome is used as medicine.Bitter, it is cold in nature.Return liver, gallbladder channel.There is heat-clearing and damp-drying drug, purging the liver of pathogenic fire courage excess fire
Effect.Cure mainly hypertension, dizziness and tinnitus, cholecystitis, acute infectious hepatitis, private parts be wet to itch, jaundice with damp-heat pathogen, boil carbuncle swells, mouth
The diseases such as bitter and infantile convulsion are the good medicine of hepatic cholagogic.
In detail, kuh-seng is the mutation that pulse family kuh-seng belongs to.It is distributed in Russia, Japan, India, Korea and China's Mainland
Etc. ground, be grown on the area of 1500 meters of height above sea level, it is how raw in hillside, sand ground grass slope spinney and near field.For hot dysentery, just
Blood, jaundice renal shutdown, leukorrhea with reddish discharge, swelling of vulva pruritus vulvae, eczema, wet sore, pruitus, mange leprosy；Control trichomonas vaginitis outside.
As a preferred option, the traditional Chinese medicine reagent for preventing eczema is mainly prepared from the following raw materials in parts by weight：
15 parts of litharge, 5 parts of realgar, 10 parts of frutus cnidii, 10 parts of Cortex Phellodendri, 5 parts of the fruit of summer cypress, 10 parts of ice
Piece, 5 parts of Chinese gall, 10 parts of the root bark of shaggy-fruited dittany, 5 parts of Radix Salviae Miltiorrhizae, 10 parts of felwort and 10 parts of kuh-seng.Certainly, in this hair
In bright other embodiment, optimal scheme is also related with the processing environment of drug, therefore, in the other embodiment of the present invention,
Other more preferably dosages can be selected, the embodiment of the present invention is not limited thereof.
It is further preferred that it is 0.1~0.3 part that the Chinese medicine preparation of the traditional Chinese medicine reagent of prevention eczema, which further includes parts by weight,
Essence, essence can provide enough fragrance to cover the taste of drug in itself, and user is more easily accepted by.Essence is selected from rose fragrant
It is one or more in essence, cream jasmin france, Chinese cassia tree essence, red tangerine essence, Yilan essence, sandalwood fragrance and Salvia japonica essence.
Flavoring rose essence is consoled and relexation.Cream jasmin france is consoled, analgesic activity.Chinese cassia tree essence can strengthening vital QI to eliminate pathogenic factors, it is anti-infective (anti-
Rotten antibacterial).Red tangerine essence can inspire enthusiasm, and make us glad, additionally aid digestion.Yilan essence can adjust and balance body work(
Can, it consoles, tranquil and relexation, anxiety can be eliminated, relieve pain, improve sleep, treat hypertension, can also inspire enthusiasm, resist
Depression is restored and heightens one's confidence.Sandalwood fragrance has relaxation, sedation, can antianxiety, depression and nervous, only have a headache.Mouse
Tail hay-scented essence can wind dispelling analgesic, stomach invigorating, antibacterial anti-inflammatory, cardiac stimulant is anticonvulsion, promoting menstruation；Also breathing problem and rheumatalgia can be treated.
Certainly, in other embodiments of the invention, the type of essence can also be selected according to demand, and the present invention does not limit.
The present embodiment additionally provides a kind of preparation method for the washing lotion for preventing eczema, including：
S1 mixing steps：By in the Chinese medicine preparation for preventing eczema litharge, realgar, frutus cnidii, Cortex Phellodendri, the fruit of summer cypress, ice
Piece, Chinese gall, the root bark of shaggy-fruited dittany, Radix Salviae Miltiorrhizae, felwort and kuh-seng are uniformly mixed at a temperature of 60~62 DEG C, form the first mixing
Object.
S2 extraction steps：First mixture and alcoholic solution are mixed to form the second mixture, and by the second mixture 98
Filtrate is obtained by filtration after 3~4h of tanning for the first time is carried out at a temperature of~100 DEG C.Certainly, in other embodiments of the invention,
The temperature and time of extraction can also be selected according to demand, and the present invention does not limit.
S3 concentrates pharmaceutical procedures：Filtrate is concentrated into 1000mL at a temperature of 85~90 DEG C and obtains washing for prevention eczema
Liquid.
As a preferred option, the cocnentration factor that filtrate is concentrated into 1000mL at a temperature of 85~90 DEG C is 25~40:
1。
Further, alcoholic solution is ethanol solution, and a concentration of 0.01M of ethanol solution.Certainly, the present invention other
In embodiment, concentration and the type of alcoholic solution can also be selected according to demand, such as can also be trihydroxylic alcohol etc., of the invention
It does not limit.
The embodiment of the present invention additionally provides a kind of preparation method for the ointment for preventing eczema, including：
S1 mixing steps：By in the Chinese medicine preparation for preventing eczema litharge, realgar, frutus cnidii, Cortex Phellodendri, the fruit of summer cypress, ice
Piece, Chinese gall, the root bark of shaggy-fruited dittany, Radix Salviae Miltiorrhizae, felwort and kuh-seng are uniformly mixed at a temperature of 60~62 DEG C, form third mixing
Object；
S2 extracts concentration step：It is filtered after third mixture and alcoholic solution are extracted 3~4h at a temperature of 98~100 DEG C
Extracting solution is obtained, by extracting solution according to 20~30:1 ratio is concentrated into 1000mL and obtains the 4th mixture；
S3 heating and melting steps：By in parts by weight 5~8 parts of stearic acid, 1~3 part of atoleine, 1~4
The wool grease mixing of part, and obtain the 5th mixture after being heated to fusing；
S4 cream steps：The ointment of prevention eczema is made after 4th mixture is mixed with the 5th mixture.
As a preferred option, the temperature for being heated to fusing is 98~105 DEG C, preferably 102 DEG C.
Further, it is 1~3h, preferably 2h to be heated to the time melted.
The feature and performance of the present invention are described in further detail with reference to embodiments.
Embodiment 1
A kind of washing lotion and ointment for preventing eczema is present embodiments provided, is prepared into respectively by following preparation method
It arrives：
Washing lotion：
S1 mixing steps：By in the Chinese medicine preparation for preventing eczema 4 parts of Radix Salviae Miltiorrhizae, 1 part of the fruit of summer cypress, 1 part of realgar, 1
The Chinese gall of part, 5 parts of frutus cnidii, 5 parts of Cortex Phellodendri, 5 parts of borneol, 4 parts of the root bark of shaggy-fruited dittany, 7 parts of felwort, 5 parts of kuh-seng
And 10 parts of litharge is uniformly mixed at a temperature of 60 DEG C, forms the first mixture；
S2 extraction steps：First mixture and alcoholic solution are mixed to form the second mixture, and by the second mixture 98
Filtrate is obtained by filtration after tanning 3h for the first time is carried out at a temperature of DEG C；
S3 concentrates pharmaceutical procedures：Filtrate is concentrated into 1000mL at a temperature of 85 DEG C and obtains the washing lotion of prevention eczema.
Ointment：
By in the Chinese medicine preparation for preventing eczema 4 parts of Radix Salviae Miltiorrhizae, 1 part of the fruit of summer cypress, 1 part of realgar, 1 part of Chinese gall, 5
Part frutus cnidii, 5 parts of Cortex Phellodendri, 5 parts of borneol, 4 parts of the root bark of shaggy-fruited dittany, 7 parts of felwort, 5 parts of kuh-seng and 10 parts it is close
Top monk is uniformly mixed at a temperature of 60 DEG C, forms third mixture；
S2 extracts concentration step：It is filtered after third mixture and alcoholic solution are extracted 3h at a temperature of 98~100 DEG C
To extracting solution, by extracting solution according to 20:1 ratio is concentrated into 1000mL and obtains the 4th mixture；
S3 heating and melting steps：By in parts by weight 5 parts of stearic acid, 1 part of atoleine, 1 part anhydrous
Lanolin mixes, and obtains the 5th mixture after being heated to fusing；
S4 cream steps：The ointment of prevention eczema is made after 4th mixture is mixed with the 5th mixture.
Embodiment 2
A kind of washing lotion and ointment for preventing eczema is present embodiments provided, is prepared into respectively by following preparation method
It arrives：
Washing lotion：
S1 mixing steps：By in the Chinese medicine preparation for preventing eczema 5 parts of Radix Salviae Miltiorrhizae, 5 parts of the fruit of summer cypress, 5 parts of realgar, 5
Part Chinese gall, 10 parts of frutus cnidii, 10 parts of Cortex Phellodendri, 10 parts of borneol, 10 parts of the root bark of shaggy-fruited dittany, 10 parts of felwort, 10 parts
Kuh-seng and 15 parts of litharge at a temperature of 61 DEG C be uniformly mixed, formed the first mixture；
S2 extraction steps：First mixture and alcoholic solution are mixed to form the second mixture, and by the second mixture 98
Filtrate is obtained by filtration after tanning 3.5h for the first time is carried out at a temperature of~100 DEG C；
S3 concentrates pharmaceutical procedures：Filtrate is concentrated into 1000mL at a temperature of 87 DEG C and obtains the washing lotion of prevention eczema.
Ointment：
By in the Chinese medicine preparation for preventing eczema 5 parts of Radix Salviae Miltiorrhizae, 5 parts of the fruit of summer cypress, 5 parts of realgar, 5 parts of Chinese gall,
10 parts of frutus cnidii, 10 parts of Cortex Phellodendri, 10 parts of borneol, 10 parts of the root bark of shaggy-fruited dittany, 10 parts of felwort, 10 parts of kuh-seng and 15
The litharge of part is uniformly mixed at a temperature of 62 DEG C, forms third mixture；
S2 extracts concentration step：Third mixture and alcoholic solution are extracted at a temperature of 100 DEG C to be obtained by filtration after 2h and carried
Liquid is taken, by extracting solution according to 30:1 ratio is concentrated into 1000mL and obtains the 4th mixture；
S3 heating and melting steps：By in parts by weight 8 parts of stearic acid, 3 parts of atoleine, 4 parts anhydrous
Lanolin mixes, and obtains the 5th mixture after being heated to fusing；
S4 cream steps：The ointment of prevention eczema is made after 4th mixture is mixed with the 5th mixture.
Embodiment 3
A kind of washing lotion and ointment for preventing eczema is present embodiments provided, is prepared into respectively by following preparation method
It arrives：
Washing lotion：
S1 mixing steps：By in the Chinese medicine preparation for preventing eczema 7 parts of Radix Salviae Miltiorrhizae, 8 parts of the fruit of summer cypress, 10 parts of realgar, 6
Part Chinese gall, 15 parts of frutus cnidii, 15 parts of Cortex Phellodendri, 15 parts of borneol, 12 parts of the root bark of shaggy-fruited dittany, 14 parts of felwort, 15 parts
Kuh-seng and 20 parts of litharge at a temperature of 62 DEG C be uniformly mixed, formed the first mixture；
S2 extraction steps：First mixture and alcoholic solution are mixed to form the second mixture, and by the second mixture 100
Filtrate is obtained by filtration after tanning 4h for the first time is carried out at a temperature of DEG C；
S3 concentrates pharmaceutical procedures：Filtrate is concentrated into 1000mL at a temperature of 90 DEG C and obtains the washing lotion of prevention eczema.
Ointment：
By in the Chinese medicine preparation for preventing eczema 7 parts of Radix Salviae Miltiorrhizae, 8 parts of the fruit of summer cypress, 10 parts of realgar, 6 parts of Chinese gall,
15 parts of frutus cnidii, 15 parts of Cortex Phellodendri, 15 parts of borneol, 12 parts of the root bark of shaggy-fruited dittany, 14 parts of felwort, 15 parts of kuh-seng and 20
The litharge of part is uniformly mixed at a temperature of 62 DEG C, forms third mixture；
S2 extracts concentration step：Third mixture and alcoholic solution are extracted at a temperature of 100 DEG C to be obtained by filtration after 4h and carried
Liquid is taken, by extracting solution according to 30:1 ratio is concentrated into 1000mL and obtains the 4th mixture；
S3 heating and melting steps：By in parts by weight 8 parts of stearic acid, 3 parts of atoleine, 4 parts anhydrous
Lanolin mixes, and obtains the 5th mixture after being heated to fusing；
S4 cream steps：The ointment of prevention eczema is made after 4th mixture is mixed with the 5th mixture.
Comparative example 1
The traditional Chinese herb medicine of commercially available treatment eczema.
Experimental example 1
The ointment of prevention eczema and the ointment of the offer of comparative example 1 that the embodiment 1 to 3 of phase homogenous quantities provides are provided, and divided
Same type of foot's eczema is not acted on, and it is that each 1~2g of dosage was observed and remembered twice the morning and evening daily to control medication
The cure time of eczema is recorded, the results are shown in Table 1.
1. cure time of table
| Number | Time (d) |
| Embodiment 1 | 7 |
| Embodiment 2 | 6 |
| Embodiment 3 | 7 |
| Comparative example 1 | 15 |
Data according to table 1 it is found that the prevention eczema that the embodiment of the present invention provides traditional Chinese medicine reagent in contrast to
For the prior art, there is the characteristics of good effect, short treating period.
In conclusion on the one hand the Chinese medicine preparation of the embodiment of the present invention can effectively prevent eczema, on the other hand
There is good effect for the eczema that has occurred and that, the characteristics for the treatment of cycle is short, there is larger market popularization value.
Embodiments described above is part of the embodiment of the present invention, instead of all the embodiments.The reality of the present invention
The detailed description for applying example is not intended to limit the range of claimed invention, but is merely representative of the selected implementation of the present invention
Example.Based on the embodiments of the present invention, those of ordinary skill in the art are obtained without creative efforts
Every other embodiment, shall fall within the protection scope of the present invention.
Claims (10)
1. a kind of traditional Chinese medicine reagent for preventing eczema, which is characterized in that the traditional Chinese medicine reagent of the prevention eczema is mainly by following weight
The raw material of number is made：
10~20 parts of litharge, 1~10 part of realgar, 5~15 parts of frutus cnidii, 5~15 parts of Cortex Phellodendri, 1~8 part of summer cypress
Son, 5~15 parts of borneol, 1~6 part of Chinese gall, 4~12 parts of the root bark of shaggy-fruited dittany, 4~7 parts of Radix Salviae Miltiorrhizae, 7~14 parts of felwort
And 5~15 parts of kuh-seng.
2. the traditional Chinese medicine reagent of prevention eczema according to claim 1, which is characterized in that the traditional Chinese medicine reagent of the prevention eczema
Mainly it is prepared from the following raw materials in parts by weight：
15 parts of the litharge, 5 parts of the realgar, 10 parts of the frutus cnidii, 10 parts of the Cortex Phellodendri, 5 parts described
The fruit of summer cypress, 10 parts of the borneol, 5 parts of the Chinese gall, 10 parts of the root bark of shaggy-fruited dittany, 5 parts of the Radix Salviae Miltiorrhizae, 10 parts of institute
State the kuh-seng of felwort and 10 parts.
3. the traditional Chinese medicine reagent of prevention eczema according to claim 1 or 2, which is characterized in that the Chinese medicine of the prevention eczema
The Chinese medicine preparation of reagent further includes the essence that parts by weight are 0.1~0.3 part.
4. it is according to claim 3 prevention eczema traditional Chinese medicine reagent, which is characterized in that the essence be selected from flavoring rose essence,
It is one or more in cream jasmin france, Chinese cassia tree essence, red tangerine essence, Yilan essence, sandalwood fragrance and Salvia japonica essence.
5. a kind of preparation method for the washing lotion for preventing eczema, which is characterized in that including：
Mixing step：By according to any one of claims 1 to 4 prevention eczema Chinese medicine preparation in the litharge,
The realgar, the frutus cnidii, the Cortex Phellodendri, the fruit of summer cypress, the borneol, the Chinese gall, the root bark of shaggy-fruited dittany, the pellet
Ginseng, the felwort and the kuh-seng are uniformly mixed at a temperature of 60~62 DEG C, form the first mixture；
Extraction step：First mixture and alcoholic solution are mixed to form the second mixture, and second mixture is existed
Filtrate is obtained by filtration after 3~4h of tanning for the first time is carried out at a temperature of 98~100 DEG C；
Concentrate pharmaceutical procedures：The filtrate is concentrated into 1000mL at a temperature of 85~90 DEG C and obtains washing for the prevention eczema
Liquid.
6. the preparation method of the washing lotion of prevention eczema according to claim 5, which is characterized in that by the filtrate 85~
The cocnentration factor that 1000mL is concentrated at a temperature of 90 DEG C is 25~40:1.
7. the preparation method of the washing lotion of prevention eczema according to claim 5, which is characterized in that the alcoholic solution is ethyl alcohol
Solution, and a concentration of 0.01M of the ethanol solution.
8. a kind of preparation method for the ointment for preventing eczema, which is characterized in that including：
Mixing step：By according to any one of claims 1 to 4 prevention eczema Chinese medicine preparation in the litharge,
The realgar, the frutus cnidii, the Cortex Phellodendri, the fruit of summer cypress, the borneol, the Chinese gall, the root bark of shaggy-fruited dittany, the pellet
Ginseng, the felwort and the kuh-seng are uniformly mixed at a temperature of 60~62 DEG C, form third mixture；
Extract concentration step：It is filtered after the third mixture and alcoholic solution are extracted 3~4h at a temperature of 98~100 DEG C
To extracting solution, by the extracting solution according to 20~30:1 ratio is concentrated into 1000mL and obtains the 4th mixture；
Heating and melting step：By in parts by weight 5~8 parts of stearic acid, 1~3 part of atoleine, 1~4 part of nothing
Water lanolin mixes, and obtains the 5th mixture after being heated to fusing；
Cream step processed：The ointment of the prevention eczema is made after 4th mixture is mixed with the 5th mixture.
9. the preparation method of the ointment of prevention eczema according to claim 8, which is characterized in that walked in the heating and melting
In rapid, the temperature for being heated to fusing is 98~105 DEG C, preferably 102 DEG C.
10. the preparation method of the ointment of prevention eczema according to claim 9, which is characterized in that in the heating and melting
In step, it is 1~3h, preferably 2h to be heated to the time melted.
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|---|---|---|---|
| CN201810019793.XA CN108126040A (en) | 2018-01-09 | 2018-01-09 | A kind of preparation method of the traditional Chinese medicine reagent for preventing eczema, washing lotion and ointment |
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