KR101543760B1 - Pharmaceutical composition for preventing and treatmenting stroke and thrombus containing traditional medical herbs - Google Patents

Abstract

The present invention relates to a pharmaceutical composition for treating and preventing stroke and thrombus and, more specifically, to a pharmaceutical composition for treating and preventing stroke and thrombus, which is produced by medicinal herbs of ginger extract, pinellia, cinnamomi ramulus, paeonia japonica, atractylodes rhizome alba, citrus unshiu, aurantii fructus, citri reticulatae viride pericarpium, lindera strichnifolia Fernandez-Villar, arisaema amurense var. serratum, mucunae caulis, roasted glycyrrhiza uralensis FISCH, etc, wherein the materials have excellent pharmacological effects for stroke and thrombus. A pharmaceutical composition containing herbal extracts for treating and preventing stroke and thrombus according to the present invention is produced by extracting a mixture of ginger extract, pinellia, Cinnamomi Ramulus, Paeonia japonica, Atractylodes Rhizome Alba, Citrus unshiu, Aurantii Fructus, Citri reticulatae viride pericarpium, lindera strichnifolia Fernandez-Villar, Arisaema amurense var. serratum, Mucunae caulis, roasted Glycyrrhiza uralensis FISCH. The pharmaceutical composition for treating and preventing stroke and thrombus according to the present invention is manufactured by mixing 16 parts by weight of of ginger extract, 2 parts by weight of pinellia, 2 parts by weight of Cinnamomi Ramulus, 1 parts by weight of Paeonia japonica, 1 parts by weight of Atractylodes Rhizome alba, 1 parts by weight of Citrus unshiu, 1 parts by weight of Aurantii Fructus, 1 parts by weight of Citri reticulatae viride pericarpium, 1 parts by weight of lindera strichnifolia Fernandez-Villar, 1 parts by weight of Arisaema amurense var. serratum, 1 parts by weight of roasted Glycyrrhiza uralensis FISCH, 5 parts by weight of Mucunae Caulis at the mixing ratio.

Description

[0001] The present invention relates to a pharmaceutical composition for prevention and treatment of stroke and thrombosis,

The present invention relates to a medicinal composition for treating paralysis and thrombosis, and more particularly to a medicinal composition for treating paralysis and thrombosis, and more particularly to a medicinal composition for treating paralysis and thrombosis, which comprises a ginger extract having an excellent pharmacological effect on paralysis and thrombus, The present invention relates to a medicinal composition for treating paralysis and thrombosis,

Stroke is a medical illness which is caused by paralysis of a part of the body such as whole body, half body or limb. It is divided into the wind, wind, and eccentricity according to the symptom, and the middle, middle, .

A typical term for modern medicine, which refers to stroke, is stroke (stroke). The cause is cerebral hemorrhage, which causes cerebral arteriovenous rupture and hemorrhage in the brain, and cerebral infarction, in which the lump of blood is blocked in the arteries of the brain and the blood can no longer flow there. Cerebral hemorrhage is a major cause of blood pressure disease (blood pressure disease), and cerebral infarction is also related to the turbidity of blood. Most of the symptoms are followed by a coma at first, and then it is usual that even if it wakes up, it becomes semi-conscious with aftereffects.

When blood vessels are injured in blood vessels due to injury of blood vessel endothelium, inflammation, change of blood flow, and enhancement of blood coagulation ability, blood coagulation mechanism starts and blood cells coagulate to block the intestinal lumen . Cerebral thrombosis is a typical disease.

Currently, the treatment of paralysis and thrombosis includes the use of emergency treatment regimens such as Wu Huang Qingyuan, Jibodan, Hsien Shuji, and acupuncture therapy ).

However, the prior art regenerative medicine used as a conventional treatment for stroke and thrombosis has a problem that the pharmacological component is too strong to be used for preventive purposes, resulting in side effects.

Korean Patent No. 10-1228465 discloses a herbal pharmaceutical composition for treating depression, a formulation thereof, a method for preparing the same, and uses thereof

DISCLOSURE Technical Problem The present invention has been devised in order to solve the above-mentioned problems, and it is an object of the present invention to provide an active ingredient for stroke and thrombosis, which comprises ginger extract, ginger extract, The present invention provides a safe traditional herbal medicine composition which is excellent in prevention and treatment of stroke, blood clot, and therapeutic effect.

It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory and are not restrictive of the invention as set forth in the accompanying drawings. It will be possible.

The medicinal composition for treating paralysis and thrombus according to the present invention is a medicinal composition for treating paralysis and thrombosis, which comprises a herbal extract, which comprises at least one of ginger extract, Which is characterized in that it is prepared by extracting a mixture containing guar gum.

The medicinal composition for treating paralysis and thrombosis according to the present invention contains 16 parts by weight of a ginger extract, 2 parts by weight of a ginger extract, 2 parts by weight of a ginger, 1 part by weight of a ginger extract, 1 part by weight of an extract, 1 part by weight of a dermis, , 1 part by weight of chewing gum, 1 part by weight of miso, 1 part by weight of male, 1 part by weight of guar gum, and 5 parts by weight of blood.

The medicinal composition for treating paralysis and thrombus according to the present invention provides a medicinal composition capable of safely preventing and treating thrombosis and stroke without side effects in a simple process using a medicinal substance having a pharmacological component in the paralysis and thrombosis .

In addition, the pharmaceutical composition for treating paralysis and thrombosis of the present invention enables the thrombolytic action through the pharmacological component of the medicinal substance contained in the composition to be used for the treatment of stroke, myocardial infarction, cerebral infarction, arteriosclerosis, arterial embolism, , Hypertension and other diseases caused by thrombosis can be treated and can be effective in improving blood circulation.

Brief Description of the Drawings Fig. 1 is a flow chart showing a method for manufacturing a pharmaceutical composition for treating paralysis and thrombus of the present invention. Fig.

The present invention relates to a medicinal composition for treating paralysis and thrombosis, and more particularly to a medicinal composition for treating paralysis and thrombosis, and more particularly to a medicinal composition for treating paralysis and thrombosis, which comprises a ginger extract having an excellent pharmacological effect on paralysis and thrombus, The present invention relates to a medicinal composition for treating paralysis and thrombosis,

The medicinal composition for treating paralysis and thrombus according to the present invention is composed of a traditional Chinese medicinal substance. Specifically, 16 parts by weight of ginger extract, 2 parts by weight of undergarments, 2 parts by weight of clinging agent, 1 part by weight of vinegar, 1 part by weight of alum, 1 part by weight of chewing gum, 1 part by weight of chewing gum, 1 part by weight of male, 1 part by weight of guar gum, and 5 parts by weight of blood.

Preferably, the medicinal composition for treating paralysis and thrombosis of the present invention comprises active ingredients based on a traditional medicinal herb, and the medicinal composition is used to prevent and treat stroke and thrombosis.

The ginger contained in the medicinal composition has pharmacological action, which promotes gastric juice secretion, digestive power enhancement, cardiac excitatory action, blood circulation promotion, and acaricidal action. Chinese characters include gangguk, manggang, white lantern, brilliant element, cognitive herb, jagang, jagang, It is also called health. Ginger is good for blood circulation, it warms the body and is effective for stroke.

It is said to be a perennial herb and is distributed all over Southeast Asia such as China, Japan, and Korea and is cultivated nationwide in Korea. It has the effect of counteracting giddiness, soothing the breathing center and eliminating spasm of the bronchial tree. In the main river gangmyeon, it eliminates the cold spots and cures the cold and cold caused by the loss of the lungs. It relieves chest tightness, eliminates the upper part of the diaphragmatic phlegm, treats cold symptoms of the chest, (胃气) to control the spleen (濕) of the treatment of the 痰 (痰) due to the headache caused by the treatment of the headache and eliminates the annoying.

The staple is a medicinal substance made of young branches of broodstock or other related plants. It has a unique fragrance. The skin part is thicker, and the medicine is spicy and warm. The stomach opens the pores of the skin in the early cold to sweat, relieves the pain of the shoulder and back, the pain of the limbs, promotes the circulation of the blood, and cures the lack of ovaries.

The herbal remedy functions on the liver and spleen to show the convergence and the heat-releasing action, releasing the union of the liver and decreasing the pain, and the pain is accompanied by various symptoms such as menstrual irregularities, menstrual cramps, cold sweats, chest, It has effects on spasticity of the limbs and pain. The major pharmacological action of the albedo is to expand the blood vessels to increase blood flow and inhibit platelet aggregation.

The exudate has a peculiar smell, a little bit of taste, and it is viscous and chewy when chewed. It is weak in the function of 脾 胃 (脾胃), news, mala appearance, yellow color of the face is diluted, the diarrhea is good, and the water is stagnant, the whole body is swollen, helps digestion of water when not digested. It can also be used for chest leaks, coughs and clear sputum caused by accumulation of water and wetness in the spleen. It is also used for the vomiting of pregnancy and sweating on the skin due to fragility. do. It is also used for colds and limb pain with gastrointestinal disorders. Pharmacological increase of mice weight gain and endurance, increase phagocytic ability, promotion of cell immune function was reported. In addition, intestinal (intestinal) inhibition and control of excitement, anti-ulcer and liver function protection, immune function hyperactivity, vasodilation, diuretic and hypoglycemic action, anti-cancer action has been reported.

The dermis is a dried fruit of the mature fruit of citrus unshiu Markovich, which is an evergreen tree belonging to the genus Rutanceae, and a relative plant belonging to the same genus. The dermis is called the summation of the selfishness, dryness, and humidification talk. It has the efficacy to return the flounder and to remove the wetness. It has the digestive gas symptoms such as anorexia nausea and vomiting, and antibacterial activity.

The crust is cultivated in the southern part of Korea. The medicinal ingredient contains essential oils and flavonoids. Neohesperidin, Naringin, and Vitamin C are contained in citrus trees. The flavor is a little spicy and the fever is cool. The efficacy reduces the energy while showing a giant effect. Therefore, there is a wall in the upper part of the chest and abdomen, and it is used for symptoms that appeal to the briskness. For example, it causes a psychological shock to the nervousness, and it gives the chest a cool feeling by lowering the energy down. And because it shows the digestive process of the digestive system, it is affected by sore symptoms, areas, etc. with side effects.

The chewy peel refers to the less-ripe peel of a citrus unshiu Markovich or a relative plant. There is a sense of directional coolness, taste is a bit spicy, and the quality is slightly warm. Cheongpyee works on the liver, so it is used for chest and side, stomach pain, hepatitis, gastritis, mastitis, breast cancer. It is used for stress, for eating and curing food, for lumps in the chest, for schooling, etc. It is also applied to cirrhosis and spleen enlargement. Pharmacological action has been reported to cause the digestive tract stimulation, digestion promotion, geomorphic, anti-ulcer, antidiarrheal secretion, hypertension, elevated blood pressure, antiallergic, bile secretion promotion, uterine smooth muscle suppression,

It is a medicinal substance which has the efficacy to smooth the running of the 气, to relieve the uvyeol, to eliminate the cold and to stop the pain. It treats headache, swelling (swelling), and asthma (asthma), which are caused by falling down on the back of giga, falling down and falling down, middle ear, 脚气 病, It treats cloudiness (cloudiness).

The male is a perennial plant belonging to the Araceae family, Arisaema amurense var. serratum Nakai and A. amurense MAXIM and Northeast Asia A. heterophyllum BL. The dried tuber of Ganoderma lucidum, Jin-kyeong, alien species, and strong wind effect, and it is used for paralysis, semi-insufficiency, boil.

The guerrillosus is a perennial vegetable belonging to Leguminosae, which is roasted in a fire. The licorice is sweet and tender. When it is burnt in a fire, it becomes warmer and helps to see and treat it.

The blood and blood are slightly odorous, taste is warm, and the quality is warm. Blood circulation and blood circulation promoting action, such as menstrual cramps, menstrual irregularities and is effective in the effects of limb paralysis. It is also used when you are weak and has anemia. It also works for hypertension, heart disease and angina. Pharmacological actions include inflammation, analgesic action, kidney and uterine metabolic activation, uterine stimulation, coronary artery dilatation, and leukocyte hyperplasia.

Hereinafter, a method for preparing a pharmaceutical composition for treating paralysis and thrombosis using the pharmacological ingredients will be described in detail.

≪ Preparation method of pharmaceutical composition for treatment of stroke and thrombosis >

First, in step S101, ginger extract is prepared. Specifically, ginger extract is prepared using raw ginger. Grind raw ginger and filter it to get rid of the extract. Thereafter, ginger extract is prepared by mixing distilled water with the extract except for the residue.

The ratio of the distilled water mixed with the extract at the time of preparing the ginger extract is from 2.5 to 3.0 parts by weight of distilled water per 1 part by weight of the extract. When the amount of distilled water mixed with the extract is less than 2.5 parts by weight, it is difficult to be mixed with the medicinal materials because of high viscosity. When the amount exceeds 3.0 parts by weight, it is difficult to sufficiently transfer the medicinal ingredient of ginger.

Next, in the second step (S102), the medicines are weighed. Specifically, ginger extract contained in the medicinal composition of the present invention is measured according to the blending ratio, such as ginger extract, ginger, loquat, vinegar, dandelion, crust, crustacean,

The mixture ratio of the herbal extracts was 16 parts by weight of ginger extract, 2 parts by weight of undiluted glue, 2 parts by weight of ginger, 1 part by weight of vinegar, 1 part by weight of extract, 1 part by weight of dermis, 1 part by weight of crust, 1 part by weight of chewing gum, 1 part by weight of male, 1 part by weight of goitreose, and 5 parts by weight of blood.

The mixing ratio of the medicines has been proposed in consideration of the quantity and the negative nature of the medicaments, the pharmacological effect on the stroke and the thrombosis, side effects due to toxicity, and the taste and flavor in the preparation of the medicinal herb. Therefore, And as a composition for prevention and treatment of thrombosis.

It is preferable to use the dried gingerbread samples such as ginger extracts, ginger extracts, vinegar extracts, extracts, dermis, crusts, chewing gum,

Next, in the third step (S103), a mixture is prepared by mixing ginger extract, ginger, clam, vinegar, alfalfa, dermis, crust, crustacean, Specifically, the above ginger extracts, ginger extracts, ginseng, white peony, liquorice, dermis, crust, crustacean, omega, man, blood, etc. are mixed and mixed well.

Next, in the fourth step (S104), the mixture is used as a pills or as a hot water bath. Specifically, the mixture is prepared as a pellet using a general method or in a pressure cooker for 4 to 5 hours.

It is difficult to sufficiently extract the pharmacological components of the pharmacological ingredients in the mixture when the pharmacological treatment is performed for less than 4 hours in the pressure boiler, and when the pharmacological treatment is performed for more than 5 hours, the efficiency of the operation may be deteriorated.

It is preferable that the above-described ginseng is packaged in a ceramic container and stored at room temperature. It is effective to take at least 10 days when ingested, and the stored drug can be kept for 1 to 2 years.

In the following, experiments were conducted to examine the pharmacological effects of the pharmaceutical composition for treating paralysis and thrombosis of the present invention, and the results are shown below.

<Experiments to prevent stroke>

This experiment was conducted to examine the preventive effect of the medicinal composition for treating paralysis and thrombosis, and 50 patients were selected from the 50s, 60s, and 70s who frequently feel paralysis, dizziness and drowsiness, The purpose of this study was to evaluate the effectiveness of the training program.

The test items were 9 points for symptom improvement, 1 point for no symptom, and 1 point for no symptoms.

In this experiment, the medicinal composition for treating paralysis and thrombosis, which was prepared by using the above-described manufacturing method, was taken at a daily dose of one capsule.

Hands and feet dizziness drowsiness Unhealthy One One One 5 days taking 2.3 1.2 1.5 10 days taking 4.8 3.2 3.1 Take 15 days 5.1 3.4 3.2 Take more than 30 days 5.6 3.8 3.3

As a result of the above test results, the examinees who took the medicinal composition for treating paralysis and thrombosis of the present invention for a long period of 10 days or longer significantly reduced numbness, dizziness and drowsiness.

Therefore, it can be seen that when the medicinal composition for treating paralysis and thrombosis according to the present invention is taken for 10 days or longer, it is effective for prevention of stroke.

S101. A first step of preparing a ginger extract;
S102. A second step of measuring the ginger extract, the ginger extract, the ginger extract, the ginger extract, the vinegar extract, the extract, the dermis, the crust,
S103. A third step of preparing a mixture by mixing ginger extract, ginger extract, ginger, milky lotion, extract, dermis, crust, crustacean,
S104. A fourth step of preparing a pellet using the mixture, or preparing a pellet by pelletizing the mixture;

Claims (5)

A medicinal composition for treating paralysis and thrombosis comprising a herbal medicine extract,
16 parts by weight of ginger extract, 2 parts by weight of undiluted glue, 2 parts by weight of ginger, 1 part by weight of vinegar, 1 part by weight of alum, 1 part by weight of dermis, 1 part by weight of crust, 1 part by weight of chewing gum, , 1 part by weight of guinea moss, 5 parts by weight of blood, etc.,
The ginger extract is obtained by grinding and filtering a fresh river, and the extract excluding the residue is mixed with distilled water,
Wherein the mixing ratio of the extract to distilled water is 2.5 to 3.0 parts by weight of distilled water per 1 part by weight of the extract. delete The method according to claim 1,
A medicinal composition for treating paralysis and thrombosis, which is characterized in that the guar gum is dried, such as gum, vinegar, alopecia, dermis, crust, The method according to claim 1,
The extracted medicinal composition for treating paralysis and thrombosis can be ingested for 4 to 5 hours in a pressure booster or by being made into pills. A first step of preparing a ginger extract;
A second step of measuring the ginger extract, the ginger extract, the ginger extract, the ginger extract, the vinegar extract, the extract, the dermis, the crust,
A third step of preparing a mixture by mixing ginger extract, ginger extract, ginger, milky lotion, extract, dermis, crust, crustacean,
A fourth step of preparing a pellet using the mixture, or preparing a pellet by pelletizing the mixture; Wherein the medicinal composition for treating paralysis and thrombosis comprises

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