CN108042781A - A kind of preparation method of the Chinese medicine preparation for preventing skin tinea, washing lotion and ointment - Google Patents

A kind of preparation method of the Chinese medicine preparation for preventing skin tinea, washing lotion and ointment Download PDF

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Publication number
CN108042781A
CN108042781A CN201810019342.6A CN201810019342A CN108042781A CN 108042781 A CN108042781 A CN 108042781A CN 201810019342 A CN201810019342 A CN 201810019342A CN 108042781 A CN108042781 A CN 108042781A
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parts
component
mixture
chinese
weight
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王雪
燕承勇
张珍
孙立新
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Guizhou Jian Ruian Pharmaceutical Co Ltd
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Guizhou Jian Ruian Pharmaceutical Co Ltd
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Abstract

The present invention provides the preparation methods of a kind of Chinese medicine preparation for preventing skin tinea, washing lotion and ointment, are related to the field of Chinese medicines.The raw material of the Chinese medicine preparation mainly includes：Chinese ephedra, almond, rhizoma zingiberis skin, duckweed, the root bark of shaggy-fruited dittany, dried orange peel, moutan bark, stiff silkworm, Radix Salviae Miltiorrhizae, moleplant seed, Chinese trumpet creeper and the tuber of stemona, pericarpium zanthoxyli, frutus cnidii, sulphur, Radix Astragali, Radix Glycyrrhizae, scorpio, spina gleditsiae, gleditsia sinensis, tribulus terrestris, sophora flower, the root of Chinese clematis, kuh-seng, the fruit of summer cypress, folium artemisiae argyi and Cortex Phellodendri.It is mixed after its raw material rational proportion with alcoholic solution and can obtain washing lotion after carrying out 3~4h of extraction, second 0.5~2h of extraction, concentration for the first time successively.Meanwhile raw material extract successively 3~4h, concentration after mixed with stearic acid, atoleine and wool grease after ointment can be made.The preparation being prepared can effectively various types of pruituses of prevention and treatment, and the practicality is high, meanwhile, therapeutic effect is good, has larger market popularization value.

Description

A kind of preparation method of the Chinese medicine preparation for preventing skin tinea, washing lotion and ointment
Technical field
The present invention relates to the field of Chinese medicines, and the more particularly to a kind of Chinese medicine preparation of skin tinea, washing lotion and ointment prevented Preparation method.
Background technology
Pruitus is both the cardinal symptom and an independent disease of many dermatopathies.Pruitus be dermatitis, Eczema, nettle rash, contact dermatitis, prurigo nodularis, xerodermia, mycotic infection of superficial part, psoriasis and atopic dermatitis Wait the most common clinical manifestation of skin diseases and diabetes, Intrahepatic Cholestasis, chronic kidney disease, tumour and AIDS (AIDS) The clinical manifestation for waiting systemic diseases important, seriously affects the quality of life of patient, it is necessary to timely and effectively treat.According to nerve Physiology pathogenesis and Clinical symptoms, pruitus can be divided into
Several different types：Skin source property pruitus (pruritoceptive itch) be scytitis, drying and its The pruitus that his noxious stimulation induces, the nerve fibre subunit of sensitization are the specific conduction paths of itch signal, such as scabies The pruitus that sore, nettle rash and insect bite reaction induce；Neural pathogenic pruitus (neuropathic itch) is nerve The pruitus that system injury induces, such as the pruitus that post-herpetic neuralgia patient is occurred together simultaneously, multiple sclerosis The paroxysmal pruitus that disease patient breaks out；Neurogenic pruitus (neurogenic itch) with it is normally functioning Nervous system is related, such as the pruitus of Intrahepatic Cholestasis patient；Suck k receptor stimulating agents and μ receptor blocking pharmacon cloth supports Fino It is treated effectively；In addition with spiritual source property pruitus etc..
As different types of pruitus seriously affects people's normal life work and rest, more and more researchers want to seek The targeted drug of suitable a variety of different types of skin itching symptoms is looked for, but result is unsatisfactory.Current existing drug There are the problems such as effect is poor, treatment type is limited to, the presence of these problems seriously hinders the progress and development of industry.
The content of the invention
First of the present invention is designed to provide a kind of Chinese medicine preparation for preventing skin tinea, this Chinese medicine preparation can be effective The various types of pruituses of ground prevention and treatment, practicability is high, meanwhile, therapeutic effect is good, has larger marketing valency Value.
Second object of the present invention is to provide a kind of preparation method for the washing lotion for preventing skin tinea, this preparation method Simply, it is feasible, the Chinese medicine preparation being prepared can effectively various types of pruituses of prevention and treatment, practicability is high, together When, therapeutic effect is good, has larger market popularization value.
Third object of the present invention is to provide a kind of preparation method for the ointment for preventing skin tinea, this preparation method Simply, it is feasible, the Chinese medicine preparation being prepared can effectively various types of pruituses of prevention and treatment, practicability is high, together When, therapeutic effect is good, has larger market popularization value.
The present invention is solved its technical problem and is realized using following technical scheme.
The present invention proposes a kind of Chinese medicine preparation for preventing skin tinea, and the Chinese medicine preparation for preventing skin tinea mainly passes through weight Amount is than being 1:1:2~3 parts of the first component, the second component and third component is made after mixing；
Wherein, the first component mainly include 1~5 part of Chinese ephedra in parts by weight, 3~6 parts of almond, 2~7 parts Rhizoma zingiberis skin, 3~7 parts of duckweed, 10~20 parts of the root bark of shaggy-fruited dittany, 7~10 parts of dried orange peel, 6~14 parts of moutan bark, 4~15 parts Stiff silkworm, 4~20 parts of Radix Salviae Miltiorrhizae, 1~5 part of moleplant seed, 4~10 parts of Chinese trumpet creeper and 2~8 parts of the tuber of stemona；
Wherein, the second component mainly include 1~10 part of ching-chieh in parts by weight, 2~13 parts it is windproof, 1 ~5 parts of cicada slough, 2~14 parts of great burdock achene, 3~12 parts of Radix Rehmanniae, 2~7 parts of peppermint, 4~10 parts of Radix Astragali, 2~13 parts Pericarpium zanthoxyli, 16~30 parts of frutus cnidii, 5~15 parts of sulphur and 3~13 parts of Radix Glycyrrhizae；
Wherein, third component mainly includes 1~7 part of scorpio in parts by weight, 3~15 parts of spina gleditsiae, 5~8 Part gleditsia sinensis, 12~14 parts of tribulus terrestris, 7~10 parts of sophora flower, 12~17 parts of the root of Chinese clematis, 2~13 parts of kuh-seng, 4~20 The fruit of summer cypress, 10~30 parts of folium artemisiae argyi and 1~14 part of Cortex Phellodendri of part.
The present invention proposes a kind of preparation method for the Chinese medicine preparation for preventing skin tinea, including：
It is 1 by weight ratio:1:2~3 parts of the first component, the second component and third component obtains the first mixing after mixing Object；
Wherein, the first component mainly include 1~5 part of Chinese ephedra in parts by weight, 3~6 parts of almond, 2~7 parts Rhizoma zingiberis skin, 3~7 parts of duckweed, 10~20 parts of the root bark of shaggy-fruited dittany, 7~10 parts of dried orange peel, 6~14 parts of moutan bark, 4~15 parts Stiff silkworm, 4~20 parts of Radix Salviae Miltiorrhizae, 1~5 part of moleplant seed, 4~10 parts of Chinese trumpet creeper and 2~8 parts of the tuber of stemona；
Wherein, the second component mainly include 1~10 part of ching-chieh in parts by weight, 2~13 parts it is windproof, 1 ~5 parts of cicada slough, 2~14 parts of great burdock achene, 3~12 parts of Radix Rehmanniae, 2~7 parts of peppermint, 4~10 parts of Radix Astragali, 2~13 parts Pericarpium zanthoxyli, 16~30 parts of frutus cnidii, 5~15 parts of sulphur and 3~13 parts of Radix Glycyrrhizae；
Wherein, third component mainly includes 1~7 part of scorpio in parts by weight, 3~15 parts of spina gleditsiae, 5~8 Part gleditsia sinensis, 12~14 parts of tribulus terrestris, 7~10 parts of sophora flower, 12~17 parts of the root of Chinese clematis, 2~13 parts of kuh-seng, 4~20 The fruit of summer cypress, 10~30 parts of folium artemisiae argyi and 1~14 part of Cortex Phellodendri of part.
The advantageous effect of the preparation method of the prevention Chinese medicine preparation of skin tinea of the embodiment of the present invention, washing lotion and ointment It is：
The Chinese medicine preparation of the prevention skin tinea of offer includes the first component, the second component and the 3rd after rational proportion Component.First component can effectively be directed to wind-cold type cutaneous pruritus.Second component can effectively be directed to wind-heat type skin itch. Third component can effectively be directed to rheumatic skin itch.Triplicity enables this important preparation to be directed to various types of skins Skin itch.
Meanwhile first the favus skin contained in component can improve the therapeutic effect of the second component, contain in the first component Moutan bark and stiff silkworm can improve the mass effect of third component.The effect of three component rational proportions can obtain more.
It also, can be with by mixed first component, the second component and the obtained hybrid medicine of third component Effectively type pruitus of itching is caused for stupid wet type, blood-deficiency and wind-dry type and worm poison so that the practicability of this important preparation obtains It effectively improves, and then improves therapeutic effect and economic benefit.
Specific embodiment
It, below will be in the embodiment of the present invention to make the purpose, technical scheme and advantage of the embodiment of the present invention clearer Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, builds according to normal condition or manufacturer The condition of view carries out.Reagents or instruments used without specified manufacturer is the conventional production that can be obtained by commercially available purchase Product.
Chinese medicine preparation of prevention skin tinea of the embodiment of the present invention and preparation method thereof is specifically described below.
A kind of Chinese medicine preparation for preventing skin tinea, the Chinese medicine preparation for preventing skin tinea is mainly 1 by weight ratio:1: 2~3 parts of the first component, the second component and third component is made after mixing；
Wherein, the first component mainly include 1~5 part of Chinese ephedra in parts by weight, 3~6 parts of almond, 2~7 parts Rhizoma zingiberis skin, 3~7 parts of duckweed, 10~20 parts of the root bark of shaggy-fruited dittany, 7~10 parts of dried orange peel, 6~14 parts of moutan bark, 4~15 parts Stiff silkworm, 4~20 parts of Radix Salviae Miltiorrhizae, 1~5 part of moleplant seed, 4~10 parts of Chinese trumpet creeper and 2~8 parts of the tuber of stemona；
Wherein, the second component mainly include 1~10 part of ching-chieh in parts by weight, 2~13 parts it is windproof, 1 ~5 parts of cicada slough, 2~14 parts of great burdock achene, 3~12 parts of Radix Rehmanniae, 2~7 parts of peppermint, 4~10 parts of Radix Astragali, 2~13 parts Pericarpium zanthoxyli, 16~30 parts of frutus cnidii, 5~15 parts of sulphur and 3~13 parts of Radix Glycyrrhizae；
Wherein, third component mainly includes 1~7 part of scorpio in parts by weight, 3~15 parts of spina gleditsiae, 5~8 Part gleditsia sinensis, 12~14 parts of tribulus terrestris, 7~10 parts of sophora flower, 12~17 parts of the root of Chinese clematis, 2~13 parts of kuh-seng, 4~20 The fruit of summer cypress, 10~30 parts of folium artemisiae argyi and 1~14 part of Cortex Phellodendri of part.
In detail, the first component can effectively be directed to wind-cold type cutaneous pruritus.It is common in nettle rash cutaneous pruritus god It is partial to chill person through property dermatitis etc..
Wherein, Chinese ephedra is the wind-cold-dispersing medicinal in Chinese medicine or Chinese medicine；Ancient times alias dragon is husky, inferior phase.Including there are three types of fiber crops The plant that Huang belongs to：Ephedra sinica (Ephedra sinica), ephedra equisetina (Ephedra equisetina) and epheday intermedia (Ephedra intermedia) uses position as herbaceous stem stem.
Wherein, almond (scientific name：Amygdalus Communis Vas) be rose family apricot seed, be divided into dessert almond and hardship Almond mainly contains protein, fat, sugar, micro amarogentin.It is mainly oleic acid and linoleic acid in the composition of fat.
Wherein, duckweed (Lemna minor) is Lemnaceae Lemna water plant, also known as blue or green duckweed, Tian Ping, duckweed grass.Extensively It is distributed in all over the world, it is common in pond, lake.Herb can make the feed of livestock and poultry.It is used as medicine with whole herb with root, cold in nature, taste Pungent, function sweating promoting eruption, clearing away heat and promoting diuresis cure mainly the diseases such as the evil fever of table, measles, oedema.
Wherein, the root bark of shaggy-fruited dittany, alias:Dittany bark, stereotyped writing ox, seguin argyreia herb, sheep fresh grass, Latin literary fame：CORTEX DICTAMNI Chinese medicine name.For Rutaceae herbaceos perennial shaggy-fruited dittany and the root skin of Dictamnus angustifolius.Main product is in Liaoning, Hebei, Sichuan, Jiangsu etc. Ground.Spring, two season of autumn excavation root, remove silt and tertia, strip root skin, cut into slices, dry.It is raw to use.With heat-clearing and damp-drying drug, wind-dispelling The effect of removing toxic substances.《Haigoushen》：" all heat toxin wind are controlled, foul wind, wind sore, mange are red rotten, and eyebrow hair is de- crisp, and musculus cutaneus is anxious, and high fever is disliked It is cold；Principal solution heat Huang, wine Huang, acute febrile, paddy Huang, labor Huang etc..”
Wherein, it is rutaceae orange and its ripe pericarp of variety.Evergreen dungarunga of tangerine or shrub, cultivate in mound Mound, low mountain zone, rivers and lakes bank or Plain.It is distributed in each department on the south the Changjiang river.During fruit maturation in 10 to December, fruit is taken It is real, pericarp is stripped, is dried in the shade or aeration-drying.Wide orange peel (dried orange peel) is cut into 3 to 4 valves more when stripping.Orange peel (dried orange peel) medicinal material point is " old Skin " and " citrus chachiensis hortorum ".
Wherein, moutan bark, Chinese medicine name.For ranunculaceae peony dry root skin.Originate in Anhui, Sichuan, Henan, Shandong etc. Ground.It is bitter, pungent, it is slightly cold, the thoughts of returning home, liver and kidney channel have clearing heat and cooling blood, activate blood circulation and disperse blood clots, reducing the asthenic fever and other effects.
Wherein, stiff silkworm, alias flying worm, ginger silkworm.It is a kind of more special product, it also known as the larva of a silkworm with batrytis are silkworm larvas In spinning cause infection muscardine and the lethal dry hardening polypide that falls ill, since its body surface gathers white hypha and mitogenetic spore Son is similar to one layer of tunica albuginea, therefore named, is mainly used for convulsion, abscess of throat, submandibular lymph nodes is scorching, facioplegia, skin scabies The illnesss such as itch.
Wherein, Radix Salviae Miltiorrhizae contains tanshinone, is robustness emmenagogue, there is the effectiveness such as dissolving stasis, raw new, promoting blood circulation, menstruation regulating, will for gynaecology Medicine cures mainly uterine hemorrhage, irregular menstruation, blood stasis, abdominal pain, dysmenorrhoea, Amenorrhea, mausoleum pain.There is good result to treatment coronary heart disease.In addition Also the weak insomnia of nerve is controlled, arthralgia, anaemia, mastitis, adenolymphitis, arthritis, boil pain is swollen, erysipelas, acute and chronic liver Inflammation, ephritis, traumatic injury, advanced schistosomiasis hepatosplenomegaly , Dian Epilepsy.External application can wash dermatitis rhus again.
Wherein, moleplant seed has the effect of expelling water retention with drastic purgative, blood-breaking eliminating mass, and external application has the effect for the treatment of tinea erosion wart.
Wherein, Campsis drug for invigorating blood circulation and eliminating stasis.
Wherein, tuber of stemona moistening lung to lower qi cough-relieving, desinsection.It coughs for new chronic cough, pulmonary tuberculosis cough, pertussis；Outside for head louse, body Lice, enterobiasis, private parts, which is disturbed, itches.The sweet tuber of stemona moistens the lung and relieve the cough.For deficiency of yin and overstrain cough.
In detail, the second component can effectively be directed to wind-heat type skin itch.It is common in the general hair of nettle rash cutaneous pruritus Nerve dermatitis etc. is partial to wind-heat person or angioneurotic edema.
Wherein, fry charcoal and be then used to stop blooding the effect of ching-chieh belongs to one medicine of schizonepeta, and life is with expelling pathogenic wind from the body surface.With windproof, Qiang It is living, control chill table disease；With honeysuckle flower, Fructus Forsythiae, peppermint, wind-heat table disease is controlled；With gypsum, headache due to pathogenic wind-heat is controlled；With great burdock achene, campanulaceae, Licorice controls abscess of throat；With charred Flos Sophorae, treating hematochezia；With rhizoma imperatae, nosebleed epistaxis is controlled.Schizonepeta and purple perilla energy inducing sweat and dispelling exogenous evils, but purple Cold dispelling power of reviving is strong, enters qi leel partially, and can regulating the flow of QI to ease the stomach；And schizonepeta wind-dispelling power wins, and enters blood system partially, frying charcoal can stop blooding again.It is therefore resonable Purple perilla is commonly used in gas side, and schizonepeta is mostly used among blood-regulating prescription.
Wherein, windproof acrid flavour, sweet, slightly warm in nature.It expels pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, only the effect of convulsion.
Wherein, cicada slough relieve heat removes heat, and relieving sore-throat, promoting eruption moves back screen, spasmolysis.For anemopyretic cold, pharyngalgia, hoarse voice, measles is not Thoroughly, rubella itch, cataract, convulsion, lockjaw.
Wherein, great burdock achene has dispelling wind and heat from the body, facilitaing lung promoting eruption, relieving sore-throat dissipating bind, the efficacy of removing toxicity for detumescence effect.Belong in diaphoretic medicine Wind-heat-dispersing medicinal.
Wherein, Radix Rehmanniae has the effect of clearing heat and cooling blood, beneficial Yin and promoting production of body liquid.
Wherein, peppermint has a dispelling wind, heat dissipation, ward off it is dirty, the effect of removing toxic substances.Affection of exogenous wind-heat is controlled, is had a headache, hot eyes, abscess of throat, Food stagnation inflatable, aphtha, toothache, sore scabies, urticaria.
Wherein, Radix Astragali has the effect of invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation.For treatment deficiency of vital energy weak, deficiency of food Loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, ulcer is difficult to burst, burst for a long time and does not holds back, blood deficiency chlorosis, Heat Diabetes.
Wherein, pericarpium zanthoxyli can remove the stink smell of various meats；Promote salivary secretion, increase appetite；It distends the blood vessels, so as to rise To the effect to reduce blood pressure；Parasite can be removed by taking pepper water；Have fragrant stomach invigorating, warming spleen and stomach for dispelling cold, damp dispelling and pain relieving, desinsection removing toxic substances, The effect of antipruritic solution raw meat.
Wherein, frutus cnidii warming kidney and enhancing body, eliminating dampness, wind-dispelling, desinsection.For impotence, Gong Leng, morbid leucorrhoea duye, arthritis with fixed pain caused by dampness pain in the back；Outside Control eczema of vulva, married woman's pruritus vulvae, trichomonas vaginitis.
Wherein, the Sublimated Sulphur in sulphur is also known as flowers of sulfur, is contacted with skin and tissue, raw under the action of its secretion Sulphidisation, having makes dermalaxia and bactericidal effect.Precipitated sulfur be also known as sulphur breast, with skin contact its secretion effect Under can generate hydrogen sulfide and pentathionic acid, play the role of sterilization, kill scabies.
Wherein, radix glycyrrhizae taste is sweet, it is mild-natured and, enter the heart, spleen, lung, stomach four and pass through.It is raw with cooler, can purging intense heat and detonicating, emergency stop Bitterly；Toast partial temperature can dissipate exterior cold, tonifying middle-Jiao and Qi.In addition, Radix Glycyrrhizae is also good at mediation property of medicine, the poison of hundred medicines is solved.
In detail, third component can effectively be directed to rheumatic skin itch.It is common in the chronic pruritic skin of stubbornness Sick such as chronic eczema, chronic scrotum eczema, neurodermatitis, prurigo nodularis cutaneous pruritus.
Wherein, scorpio ceases wind antispastic, dispersing pathogen accumulation are removed obstruction in channels to relieve pain.
Wherein, spina gleditsiae sterilizes saturating purulence, searches wind, desinsection.Main swollen ulcer drug, scrofula, sore rash stubborn dermatitis；Hypogalactia after delivery, afterbirth is not Under, pestilential wind.
Wherein, the natural activities composition gleditsins such as triterpenoid saponin are contained in the Chinese honey locust pod of gleditsia sinensis).Gleditschiasaponin is one The natural products that kind medicine, food and daily chemical industry have wide application prospects；Contain abundant gleditsin in Chinese honey locust pulp, often Silk and precious metal are washed with it, plating metal is cleaned with it, makees the foaming agent of lightweight concrete with it, preparing foam with it Extinguishing chemical prepares agricultural chemical insecticide etc. with it.Saponin is non-stimulated to skin, harmless, pure natural detergent product market It has a high potential.
Wherein, tribulus terrestris flat liver solution strongly fragrant, dispelling pathogenic wind for improving eyesight.It has a headache for dizziness due to hyperactivity of liver-YANG, liver-depressed hypochondrium pain, headache due to pathogenic wind-heat, hot eyes The diseases such as swelling and pain, pruitus.
Wherein, sophora flower bitter, it is mild-natured, it is nontoxic, there is heat-clearing, cool blood, hemostasis, decompression.To haematemesis, hematuria, hemorrhoid Sore bleeding, wind-heat hot eyes, high blood pressure, hyperlipidemia, the tuberculosis of cervical lymph nodes, vascular sclerosis, stool band blood, diabetes, retina Inflammation, psoriasis etc. have significant curative effect；Can with expelling parasite, control pharyngitis.Sophora flower can enhance the resistance of capillary, reduce blood vessel and lead to Permeability can make brittleness blood vessel recover the function of elasticity, so as to reducing blood lipid and prevent vascular sclerosis.
Wherein, the root of Chinese clematis has dispelling wind and eliminating dampness, the effect of removing obstruction in channels to relieve pain.For arthralgia pain due to rheumatism, extremity numbness, tendon and vessel is arrested Contraction, joint stuffiness, bone are choked with sobs the diseases such as larynx.
Wherein, kuh-seng is used for hot dysentery, has blood in stool, jaundice renal shutdown, leukorrhea with reddish discharge, swelling of vulva pruritus vulvae, eczema, wet sore, pruitus, Mange leprosy；Control trichomonas vaginitis outside.
Wherein, fruit of summer cypress clearing heat and promoting diuresis, dispelling wind and arresting itching.For under difficulty and pain in micturition, pruritus vulvae band, rubella, eczema, skin scabies Itch.
Wherein, folium artemisiae argyi have Wen Jing, dry, cold dispelling, hemostasis, anti-inflammatory, relieving asthma, cough-relieving, tocolysis, antiallergy the effects that.
Wherein, Cortex Phellodendri bitter, it is cold in nature.It is clearing heat and detoxicating, purging intense heat eliminating dampness.Cure mainly acute bacillary dysentery, chordapsus, acute The inflammation such as icteric hepatitis, urinary system infection contamination.Burning hot wound, tympanitis, acute conjunctivitis etc. are controlled in external application.
As preferred scheme, the Chinese medicine preparation for preventing skin tinea is mainly 1 by weight ratio:1:First group of 2 parts Divide, be made after the second component and third component mixing；
Wherein, the first component mainly include 3 parts of Chinese ephedra in parts by weight, 5 parts of almond, 4 parts of rhizoma zingiberis skin, 5 parts of duckweed, 15 parts of the root bark of shaggy-fruited dittany, 8 parts of dried orange peel, 10 parts of moutan bark, 8 parts of stiff silkworm, 10 parts of Radix Salviae Miltiorrhizae, 3 parts a thousand pieces of gold Son, 6 parts of Chinese trumpet creeper and 5 parts of the tuber of stemona；
Wherein, the second component mainly include 8 parts of ching-chieh in parts by weight, 7 parts windproof, 3 parts of cicada slough, 8 parts of great burdock achene, 8 parts of Radix Rehmanniae, 5 parts of peppermint, 6 parts of Radix Astragali, 7 parts of pericarpium zanthoxyli, 18 parts of frutus cnidii, 8 parts of sulphur with And 5 parts of Radix Glycyrrhizae；
Wherein, third component mainly includes 5 parts of scorpio in parts by weight, 8 parts of spina gleditsiae, 7 parts of gleditsia sinensis, 13 Part tribulus terrestris, 8 parts of sophora flower, 15 parts of the root of Chinese clematis, 10 parts of kuh-seng, 15 parts of the fruit of summer cypress, 20 parts of folium artemisiae argyi and 10 parts Cortex Phellodendri.
It should be noted that the favus skin contained in the first component can improve the therapeutic effect of the second component, the first component In the moutan bark that contains and stiff silkworm can improve the mass effect of third component.Three component rational proportions can be treated more Effect.
It also, can be with by mixed first component, the second component and the obtained hybrid medicine of third component Effectively type pruitus of itching is caused for stupid wet type, blood-deficiency and wind-dry type and worm poison so that the practicability of this important preparation obtains It effectively improves, and then improves therapeutic effect and economic benefit.
It is further preferred that the Chinese medicine preparation of prevention skin tinea further includes 2~6 parts of Fu in parts by weight Siberian cocklebur, 2~8 parts of Rhizoma Atractylodis Macrocephalae and 3~15 parts of plantain seed.The addition of this three tastes medicine can be strengthened treating stupid wet type skin pruritus Therapeutic effect.Poria cocos contains pachyman has humidification to normal immune function, can enhance macrophage phagocytic function.
It is further preferred that the Chinese medicine preparation of prevention skin tinea further includes the perfume (or spice) that parts by weight are 0.1~0.3 part Essence.Essence can provide enough fragrance to cover the taste of drug in itself, and user is more easily accepted by.Essence be selected from flavoring rose essence, One or more in cream jasmin france, Chinese cassia tree essence, red tangerine essence, Yilan essence, sandalwood fragrance and Salvia japonica essence.Rose Essence is consoled and relexation.Cream jasmin france is consoled, analgesic activity.Chinese cassia tree essence can strengthening vital QI to eliminate pathogenic factors, it is anti-infective that (anti-corrosion resists Bacterium).Red tangerine essence can inspire enthusiasm, and make us glad, additionally aid digestion.Yilan essence can adjust and balance body function, have It consoles, tranquil and relexation, anxiety can be eliminated, relieve pain, improve sleep, treat hypertension, can also inspire enthusiasm, antidepression, Recover and heighten one's confidence.Sandalwood fragrance has relaxation, sedation, can antianxiety, depression and nervous, only have a headache.Salvia japonica Essence can wind dispelling analgesic, stomach invigorating, antibacterial anti-inflammatory, cardiac stimulant is anticonvulsion, promoting menstruation；Also breathing problem and rheumatalgia can be treated.When So, in other embodiments of the invention, the species of essence can also make choice according to demand, and the present invention does not limit.
The embodiment of the present invention additionally provides a kind of preparation method for the washing lotion for preventing skin tinea, including：
Blend step：The first component, the second component and third component in the Chinese medicine preparation that skin tinea will be prevented are pressed It is 1 according to weight ratio:1:The first mixture is obtained after 2~3 parts of ratio mixing；
First time extraction step：It is 1 by weight ratio:25~30 ratio is formed after the first mixture is mixed with alcoholic solution Second mixture, and it is obtained by filtration first after the second mixture is carried out 3~4h of tanning for the first time at a temperature of 98~100 DEG C Filter residue and the first filtrate；
Second of extraction step：It is 1 by weight ratio:15~18 first filter residues are with alcoholic solution at a temperature of 98~100 DEG C The second filter residue and the second filtrate is obtained by filtration after carrying out second of 0.5~2h of tanning, after the first filtrate is mixed with the second filtrate Obtain the 3rd mixture；
Concentration liquid step processed：By the 3rd mixture according to cocnentration factor be 20~30:1 ratio is concentrated into 1000mL and obtains 4th mixture.
It should be noted that the first component, the second component and third component are weighed according to same standard, often A first component is weighed according to above-mentioned formula, and each second component is weighed according to above-mentioned formula, and each third component is pressed It is weighed according to above-mentioned formula.
As preferred scheme, further include：Sterilisation step：It, will in parts by weight at a temperature of 80~100 DEG C The 4th mixture after 1~3 part of fungicide concentration is mixed and stirred for uniformly.The time wherein sterilized and the selection of fungicide, It can make choice according to demand, while in other embodiments of the invention, physical sterilization can also be used, be not necessarily to Using chemical sterilization method, the present invention does not limit.
The embodiment of the present invention additionally provides a kind of preparation method for the ointment for preventing skin tinea, comprises the following steps：
Blend step：The first component, the second component and third component in the Chinese medicine preparation that skin tinea will be prevented are pressed It is 1 according to weight ratio:2:The 5th mixture is obtained after 3~4 parts of ratio mixing；
Extract concentration step：It is 1 by weight ratio:25~30 ratio the 5th mixture is mixed with alcoholic solution after 98~ Extracting solution is obtained by filtration after extracting 3~4h at a temperature of 100 DEG C, by extracting solution according to 20~30:1 ratio, is concentrated into 1000mL obtains the 6th mixture；
Heating fusing step：By in parts by weight 4~9 parts of stearic acid, 2~7 parts of atoleine, 4~9 parts Wool grease mixing, and be heated to fusing after obtain the 7th mixture；
Cream step processed：6th mixture and the 7th mixture be mixed and stirred at a temperature of 72~75 DEG C The ointment of prevention skin tinea is made after even.
Wherein, the temperature of heating is 150~300 DEG C, and heating time is 5~6h.Certainly, in the other embodiment of the present invention In, the time of heating and degree can also make choice according to demand, and the present invention does not limit.
As preferred scheme, the preparation method of the ointment of skin tinea is prevented, is further included：Prevent the ointment of skin tinea Preparation method, further include：
Sterilisation step：By the ointment for preventing skin tinea at a temperature of 100~120 DEG C, 1~4h is sterilized；Certainly, at this In the other embodiment of invention, the temperature and time of sterilization can also make choice and adjust according to demand.
Finished product packing：The ointment of prevention skin tinea after sterilization is aseptically packed.In sterilizing situation Lower packaging can be effectively prevented from the pollution of bacterium and other harmful bacterias.
The feature and performance of the present invention are described in further detail with reference to embodiments.
Embodiment 1
A kind of ointment machin washing lotion for preventing skin tinea is present embodiments provided, is prepared by the following method：
Washing lotion：
S1：Choose the first component, the second component and third component.Wherein, the first component mainly includes according to parts by weight 1 part of Chinese ephedras of number meter, 3 parts of almond, 2 parts of rhizoma zingiberis skin, 3 parts of duckweed, 10 parts of the root bark of shaggy-fruited dittany, 7 parts of dried orange peel, 6 parts Moutan bark, 4 parts of stiff silkworm, 4 parts of Radix Salviae Miltiorrhizae, 1 part of moleplant seed, 4 parts of Chinese trumpet creeper and 2 parts of the tuber of stemona；
Wherein, the second component mainly include 1 part of ching-chieh in parts by weight, 2 parts windproof, 1 part of cicada slough, 2 parts of great burdock achene, 3 parts of Radix Rehmanniae, 2 parts of peppermint, 4 parts of Radix Astragali, 2 parts of pericarpium zanthoxyli, 16 parts of frutus cnidii, 5 parts of sulphur with And 3 parts of Radix Glycyrrhizae；
Wherein, third component mainly includes 1 part of scorpio in parts by weight, 3 parts of spina gleditsiae, 5 parts of gleditsia sinensis, 12 The tribulus terrestris, 7 parts of sophora flower, 12 parts of the root of Chinese clematis, 2 parts of kuh-seng, 4 parts of the fruit of summer cypress, 10 parts of folium artemisiae argyi and 1 part of Huang of part Cypress；
S2：By the first component, the second component and third component according to weight ratio be 1:1:2 are mixed to get the first mixing Object；
S3：It is 1 by weight ratio:25 ratio forms the second mixture after the first mixture is mixed with alcoholic solution, and will The first filter residue and the first filtrate is obtained by filtration after 3~4h of tanning for the first time is carried out at a temperature of 98 DEG C in second mixture；
S4：It is 1 by weight ratio:15 first filter residues and alcoholic solution carry out mistake after second of tanning 0.5h at a temperature of 98 DEG C Filter obtains the second filter residue and the second filtrate, and the 3rd mixture is obtained after the first filtrate is mixed with the second filtrate；
S5：By the 3rd mixture according to cocnentration factor be 20:1 ratio is concentrated into 1000mL and obtains the 4th mixture；
S6：At a temperature of 80 DEG C, the 4th mixture after 1 part of fungicide concentration in parts by weight is mixed And it is uniformly mixing to obtain washing lotion.
Ointment：
S1：By the first component, the second component and the third component in the Chinese medicine preparation for preventing skin tinea according to weight Than for 1:1:The 5th mixture is obtained after 2 parts of ratio mixing；
S2：It is 1 by weight ratio:25 ratio extracts 3h after the 5th mixture is mixed with alcoholic solution at a temperature of 98 DEG C After extracting solution is obtained by filtration, by extracting solution according to 20~30:1 ratio is concentrated into 1000mL and obtains the 6th mixture；
S3：4 parts of stearic acid, 2 parts of atoleine, 4 parts of wool grease in parts by weight is mixed, and The 7th mixture is obtained after being heated to fusing；
S4：Uniformly rear be made that be mixed and stirred for of 6th mixture and the 7th mixture at a temperature of 72 DEG C is prevented Control the ointment of skin tinea.
Embodiment 2
A kind of Chinese medicine preparation for preventing skin tinea is present embodiments provided, is prepared by the following method：
Washing lotion：
S1：It chooses the first component, the second component and third component and is chosen, cleaned, dried, screened successively.Its In, the first component mainly include 3 parts of Chinese ephedra in parts by weight, 5 parts of almond, 4 parts of rhizoma zingiberis skin, 5 parts of duckweed, 15 parts of the root bark of shaggy-fruited dittany, 8 parts of dried orange peel, 10 parts of moutan bark, 8 parts of stiff silkworm, 10 parts of Radix Salviae Miltiorrhizae, 3 parts of moleplant seed, 6 parts of icepro Clouds flower and 5 parts of the tuber of stemona；
Wherein, the second component mainly include 8 parts of ching-chieh in parts by weight, 7 parts windproof, 3 parts of cicada slough, 8 parts of great burdock achene, 8 parts of Radix Rehmanniae, 5 parts of peppermint, 6 parts of Radix Astragali, 7 parts of pericarpium zanthoxyli, 18 parts of frutus cnidii, 8 parts of sulphur with And 5 parts of Radix Glycyrrhizae；
Wherein, third component mainly includes 5 parts of scorpio in parts by weight, 8 parts of spina gleditsiae, 7 parts of gleditsia sinensis, 13 Part tribulus terrestris, 8 parts of sophora flower, 15 parts of the root of Chinese clematis, 10 parts of kuh-seng, 15 parts of the fruit of summer cypress, 20 parts of folium artemisiae argyi and 10 parts Cortex Phellodendri；
S2：By the first component, the second component and third component according to weight ratio be 1:1:2.5 are mixed to get the first mixing Object；
S3：It is 1 by weight ratio:28 ratio forms the second mixture after the first mixture is mixed with alcoholic solution, and will The first filter residue and the first filtrate is obtained by filtration after tanning 3.5h for the first time is carried out at a temperature of 99 DEG C in second mixture；
S4：It is 1 by weight ratio:17 first filter residues and alcoholic solution filter after carrying out second of tanning 1h at a temperature of 99 DEG C The second filter residue and the second filtrate are obtained, the 3rd mixture is obtained after the first filtrate is mixed with the second filtrate；
S5：By the 3rd mixture according to cocnentration factor be 25:1 ratio is concentrated into 1000mL and obtains the 4th mixture；
S6：At a temperature of 90 DEG C, the 4th mixture after 2 parts of fungicide concentration in parts by weight is mixed And it is uniformly mixing to obtain washing lotion.
Ointment：
S1：By the first component, the second component and the third component in the Chinese medicine preparation for preventing skin tinea according to weight Than for 1:1:The 5th mixture is obtained after 2~3 parts of ratio mixing；
S2：It is 1 by weight ratio:25~30 ratio carries after the 5th mixture is mixed with alcoholic solution at a temperature of 97 DEG C Extracting solution is obtained by filtration after taking 3.5h, by extracting solution according to 25:1 ratio is concentrated into 1000mL and obtains the 6th mixture；
S3：6 parts of stearic acid, 5 parts of atoleine, 6 parts of wool grease in parts by weight is mixed, and The 7th mixture is obtained after being heated to fusing；
S4：Uniformly rear be made that be mixed and stirred for of 6th mixture and the 7th mixture at a temperature of 74 DEG C is prevented Control the ointment of skin tinea.
Embodiment 3
A kind of Chinese medicine preparation for preventing skin tinea is present embodiments provided, is prepared by the following method：
Washing lotion：
S1：It chooses the first component, the second component and third component and is chosen, cleaned, dried, screened successively.Its In, the first component mainly include 5 parts of Chinese ephedra in parts by weight, 6 parts of almond, 7 parts of rhizoma zingiberis skin, 7 parts of duckweed, 20 parts of the root bark of shaggy-fruited dittany, 10 parts of dried orange peel, 14 parts of moutan bark, 15 parts of stiff silkworm, 20 parts of Radix Salviae Miltiorrhizae, 5 parts of moleplant seed, 10 parts Chinese trumpet creeper and 8 parts of the tuber of stemona；
Wherein, the second component mainly includes 10 parts of ching-chieh in parts by weight, 13 parts of windproof, 5 parts of cicada Slough off, 14 parts of great burdock achene, 12 parts of Radix Rehmanniae, 7 parts of peppermint, 10 parts of Radix Astragali, 13 parts of pericarpium zanthoxyli, 30 parts of frutus cnidii, 15 parts Sulphur and 13 parts of Radix Glycyrrhizae；
Wherein, third component mainly include 7 parts of scorpio in parts by weight, 15 parts of spina gleditsiae, 8 parts of gleditsia sinensis, 14 parts of tribulus terrestris, 10 parts of sophora flower, 17 parts of the root of Chinese clematis, 13 parts of kuh-seng, 20 parts of the fruit of summer cypress, 130 parts of folium artemisiae argyi and 14 parts of Cortex Phellodendri；
S2：By the first component, the second component and third component according to weight ratio be 1:1:3 are mixed to get the first mixing Object；
S3：It is 1 by weight ratio:30 ratio forms the second mixture after the first mixture is mixed with alcoholic solution, and will The first filter residue and the first filtrate is obtained by filtration after 3~4h of tanning for the first time is carried out at a temperature of 100 DEG C in second mixture；
S4：It is 1 by weight ratio:18 first filter residues and alcoholic solution carry out mistake after second of tanning 2h at a temperature of 100 DEG C Filter obtains the second filter residue and the second filtrate, and the 3rd mixture is obtained after the first filtrate is mixed with the second filtrate；
S5：By the 3rd mixture according to cocnentration factor be 30:1 ratio is concentrated into 1000mL and obtains the 4th mixture；
S6：At a temperature of 100 DEG C, the 4th mixture after 3 parts of fungicide concentration in parts by weight is mixed Merging is uniformly mixing to obtain washing lotion.
Ointment：
S1：By the first component, the second component and the third component in the Chinese medicine preparation for preventing skin tinea according to weight Than for 1:1:The 5th mixture is obtained after 3 parts of ratio mixing；
S2：It is 1 by weight ratio:30 ratio is extracted after the 5th mixture is mixed with alcoholic solution at a temperature of 100 DEG C Extracting solution is obtained by filtration after 4h, by extracting solution according to 30:1 ratio is concentrated into 1000mL and obtains the 6th mixture；
S3：9 parts of stearic acid, 7 parts of atoleine, 9 parts of wool grease in parts by weight is mixed, and The 7th mixture is obtained after being heated to fusing；
S4：Uniformly rear be made that be mixed and stirred for of 6th mixture and the 7th mixture at a temperature of 75 DEG C is prevented Control the ointment of skin tinea.
Comparative example 1
The ointment of commercially available treatment pruitus.
Comparative example 2
The washing lotion of commercially available treatment pruitus.
Experimental example 1
Ointment that the Chinese medicine preparation that the embodiment 1 to 3 of homogenous quantities provides is provided with comparative example 1 and comparative example 2 is taken to provide Washing lotion, and be respectively acting on same type of nettle rash cutaneous pruritus, medication twice daily in morning and evening, every time with 0.5~ 1g observes and records the time of nettle rash recovery from illness, as a result such as following table.
1. cure time of table
Number The ointment time (d) The washing lotion time (d)
Embodiment 1 25 26
Embodiment 2 24 27
Embodiment 3 26 28
Comparative example 1 45 53
Comparative example 2 52 56
According to the data that table 1 is shown, the drug effect for the Chinese medicine preparation that the embodiment of the present invention provides is higher than commercially available right The medicament that ratio provides.
In conclusion the Chinese medicine preparation of the embodiment of the present invention can effectively various types of pruituses of prevention and treatment, Practicability is high, meanwhile, therapeutic effect is good, has larger market popularization value.
Embodiments described above is part of the embodiment of the present invention, instead of all the embodiments.The reality of the present invention The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of the selected implementation of the present invention Example.Based on the embodiments of the present invention, those of ordinary skill in the art are obtained without creative efforts Every other embodiment, belongs to the scope of protection of the invention.

Claims (10)

1. a kind of Chinese medicine preparation for preventing skin tinea, which is characterized in that the Chinese medicine preparation of the prevention skin tinea mainly leads to Weight ratio is crossed as 1:1:2~3 parts of the first component, the second component and third component is made after mixing；
Wherein, first component mainly include 1~5 part of Chinese ephedra in parts by weight, 3~6 parts of almond, 2~7 parts Rhizoma zingiberis skin, 3~7 parts of duckweed, 10~20 parts of the root bark of shaggy-fruited dittany, 7~10 parts of dried orange peel, 6~14 parts of moutan bark, 4~15 parts Stiff silkworm, 4~20 parts of Radix Salviae Miltiorrhizae, 1~5 part of moleplant seed, 4~10 parts of Chinese trumpet creeper and 2~8 parts of the tuber of stemona；
Wherein, second component mainly include 1~10 part of ching-chieh in parts by weight, 2~13 parts it is windproof, 1 ~5 parts of cicada slough, 2~14 parts of great burdock achene, 3~12 parts of Radix Rehmanniae, 2~7 parts of peppermint, 4~10 parts of Radix Astragali, 2~13 parts Pericarpium zanthoxyli, 16~30 parts of frutus cnidii, 5~15 parts of sulphur and 3~13 parts of Radix Glycyrrhizae；
Wherein, the third component mainly includes 1~7 part of scorpio in parts by weight, 3~15 parts of spina gleditsiae, 5~8 Part gleditsia sinensis, 12~14 parts of tribulus terrestris, 7~10 parts of sophora flower, 12~17 parts of the root of Chinese clematis, 2~13 parts of kuh-seng, 4~20 The fruit of summer cypress, 10~30 parts of folium artemisiae argyi and 1~14 part of Cortex Phellodendri of part.
2. the Chinese medicine preparation of prevention skin tinea according to claim 1, which is characterized in that the prevention skin tinea Chinese medicine preparation is mainly 1 by weight ratio:1:2 parts of first component, second component and the third component is mixed It is made after conjunction；
Wherein, first component mainly include 3 parts of the Chinese ephedra in parts by weight, 5 parts of the almond, 4 parts The rhizoma zingiberis skin, 5 parts of the duckweed, 15 parts of the root bark of shaggy-fruited dittany, 8 parts of the dried orange peel, 10 parts of the moutan bark, 8 The stiff silkworm, 10 parts of the Radix Salviae Miltiorrhizae, 3 parts of the moleplant seed, 6 parts of the Chinese trumpet creeper and 5 parts of the tuber of stemona of part；
Wherein, second component mainly include 8 parts of the ching-chieh in parts by weight, 7 parts it is described it is windproof, 3 Part the cicada slough, 8 parts of the great burdock achene, 8 parts of the Radix Rehmanniae, 5 parts of the peppermint, 6 parts of the Radix Astragali, 7 parts The pericarpium zanthoxyli, 18 parts of the frutus cnidii, 8 parts of the sulphur and 5 parts of the Radix Glycyrrhizae；
Wherein, the third component mainly include 5 parts of the scorpio in parts by weight, 8 parts of the spina gleditsiae, 7 parts The gleditsia sinensis, 13 parts of the tribulus terrestris, 8 parts of the sophora flower, 15 parts of the root of Chinese clematis, 10 parts of the kuh-seng, 15 The fruit of summer cypress, 20 parts of the folium artemisiae argyi and 10 parts of the Cortex Phellodendri of part.
3. the Chinese medicine preparation of prevention skin tinea according to claim 2, which is characterized in that the prevention skin tinea Chinese medicine preparation further includes 2~6 parts of Poria cocos, 2~8 parts of Rhizoma Atractylodis Macrocephalae and 3~15 parts of plantain seed in parts by weight.
4. the Chinese medicine preparation of prevention skin tinea according to claim 1, which is characterized in that the prevention skin tinea Chinese medicine preparation further includes the essence that parts by weight are 0.1~0.3 part, and it is fragrant that the essence is selected from flavoring rose essence, cream jasmin france, Chinese cassia tree One or more in smart, red tangerine essence, Yilan essence, sandalwood fragrance and Salvia japonica essence.
5. a kind of preparation method for the washing lotion for preventing skin tinea, which is characterized in that including：
Blend step：By described first in the Chinese medicine preparation for preventing skin tinea according to any one of claims 1 to 4 Component, second component and the third component are 1 according to weight ratio:1:It is mixed that first is obtained after 2~3 parts of ratio mixing Close object；
First time extraction step：It is 1 by weight ratio:25~30 ratio is formed after first mixture is mixed with alcoholic solution Second mixture, and be obtained by filtration after second mixture is carried out 3~4h of tanning for the first time at a temperature of 98~100 DEG C First filter residue and the first filtrate；
Second of extraction step：It is 1 by weight ratio:15~18 first filter residues are with alcoholic solution at a temperature of 98~100 DEG C The second filter residue and the second filtrate is obtained by filtration after carrying out second of 0.5~2h of tanning, by first filtrate and the described second filter The 3rd mixture is obtained after liquid mixing；
Concentration liquid step processed：By the 3rd mixture according to cocnentration factor be 20~30:1 ratio is concentrated into 1000mL and obtains 4th mixture.
6. the preparation method of the washing lotion of prevention skin tinea according to claim 5, which is characterized in that further include：
Sterilisation step：At a temperature of 80~100 DEG C, described in after 1~3 part of fungicide concentration in parts by weight 4th mixture is mixed and stirred for uniformly.
7. a kind of preparation method for the ointment for preventing skin tinea, which is characterized in that comprise the following steps：
Blend step：By described first in the Chinese medicine preparation for preventing skin tinea according to any one of claims 1 to 4 Component, second component and the third component are 1 according to weight ratio:1:It is mixed that the 5th is obtained after 2~3 parts of ratio mixing Close object；
Extract concentration step：It is 1 by weight ratio:25~30 ratio the 5th mixture is mixed with alcoholic solution after 98~ Extracting solution is obtained by filtration after extracting 3~4h at a temperature of 100 DEG C, by the extracting solution according to 20~30:1 ratio, is concentrated into 1000mL obtains the 6th mixture；
Heating fusing step：By in parts by weight 4~9 parts of stearic acid, 2~7 parts of atoleine, 4~9 parts of nothing Water lanolin mixes, and obtains the 7th mixture after being heated to fusing；
Cream step processed：By the 6th mixture and the 7th mixture being mixed at a temperature of 72~75 DEG C and stirred The ointment of the prevention skin tinea is made after mixing uniformly.
8. the preparation method of the ointment of prevention skin tinea according to claim 7, which is characterized in that the heating fusing In step, the temperature of heating is 150~300 DEG C, and heating time is 5~6h.
9. the preparation method of the ointment of prevention skin tinea according to claim 7, which is characterized in that further include：
Incubation step：7th mixture is subjected to 1~2h of heat preservation at a temperature of 68~75 DEG C.
10. the preparation method of the ointment of prevention skin tinea according to claim 9, which is characterized in that further include：
Sterilisation step：By the ointment of the prevention skin tinea at a temperature of 100~120 DEG C, 1~4h is sterilized；
Finished product packing：The ointment of the prevention skin tinea after sterilization is aseptically packed.
CN201810019342.6A 2018-01-09 2018-01-09 A kind of preparation method of the Chinese medicine preparation for preventing skin tinea, washing lotion and ointment Pending CN108042781A (en)

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Application publication date: 20180518