CN108125091A - A kind of preparation method for improving cardiovascular and cerebrovascular Chinese herbal medicine composite enzyme drink - Google Patents
A kind of preparation method for improving cardiovascular and cerebrovascular Chinese herbal medicine composite enzyme drink Download PDFInfo
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- CN108125091A CN108125091A CN201810058026.XA CN201810058026A CN108125091A CN 108125091 A CN108125091 A CN 108125091A CN 201810058026 A CN201810058026 A CN 201810058026A CN 108125091 A CN108125091 A CN 108125091A
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Abstract
The present invention relates to a kind of preparation methods for improving cardiovascular and cerebrovascular Chinese herbal medicine composite enzyme drink, take pueraria lobata, hawthorn, lotus leaf, peach kernel, safflower, matrimony vine, chrysanthemum, mulberry fruit, dried orange peel, malt, it soaks, decoct, decoction liquor cryogenic vacuum is concentrated under reduced pressure, sterilizing, filtering, filtrate is nutrient solution;Nutrient solution is placed in extractor, and brown sugar is added to be uniformly mixed to obtain culture solution;Culture solution puts cooling in fermentation tank, and inoculation rhizopus, red yeast rice strain are rear to be sealed by fermentation 36 months, and fermentation temperature is for 35 37 DEG C to get improvement cardiovascular and cerebrovascular Chinese herbal medicine composite enzyme drink.The present invention uses pueraria lobata, hawthorn, lotus leaf, peach kernel, safflower, matrimony vine, chrysanthemum, mulberry fruit, dried orange peel, malt as Solution culture method base, using rhizopus and red yeast rice bacterium composite fermentation as conversion tool, using conventional liquid zymotechnique, the venomous injurant that can be degraded in raw material, retain original active material, improve original plant open it is strongly fragrant disappear stagnant, blood circulation and channel invigorating the effect of, reaching improves human metabolism function, prevention hyperlipidemia, hypercoagulable blood, hyperglycemia, hypertension, artery sclerosis and cardiovascular and cerebrovascular disease.
Description
Technical field
The present invention relates to a kind of preparation methods for improving cardiovascular and cerebrovascular Chinese herbal medicine composite enzyme drink.
Background technology
Chinese control and prevention of disease Current Situation Investigations in 2018 of net publication and market prospects trend analysis report are investigated according to China's Industry
Accuse display, Chinese Adult Prevalence of Hypertension be up to 18.8%, about 1.6 hundred million people, every year also continue to increase 10,000,000 newly it is high
Blood pressure patient.And in the annual 3000000 dead cardiovascular patients of China, 50% is all related with hypertension.
《Chinese cardiovascular disease reports (2015)》It has been shown that, Chinese cardiovascular death rate still occupies disease death composition within 2014
First place, higher than tumour and other diseases.Rural area cardiovascular death rate is 295.63/10 ten thousand within 2014, and Heart disease is dead
It is 143.72/10 ten thousand to die rate, and mortality of cerebrovascular disease rate is 151.91/10 ten thousand (cerebral hemorrhage 74.51/10 ten thousand, cerebral infarctions 45.30/10
Ten thousand);City cardiovascular death rate is 261.99/10 ten thousand, and wherein deaths from heart disease rate is 136.21/10 ten thousand, and the cerebrovascular is died of illness
Dying rate, (cerebral hemorrhage 52.25/10 ten thousand, cerebral infarction 41.99/10 is ten thousand) for 125.78/10 ten thousand.Cardiovascular disease relatively common at present
For:During brain is sudden, coronary heart disease, arrhythmia cordis, heart failure, lung cardiovascular disease, department of cardiovascular surgery, chronic kidney disease, peripheral blood vessel
Disease.The number that China dies of cardiovascular and cerebrovascular disease every year reaches 3,500,000 people, wherein the patient for dying of angiocardiopathy accounts for total death
The 30-40% of number.In whole causes of death, the death rate of angiocardiopathy and cranial vascular disease is 21.45% He respectively
19.61%, divide and arrange the 2nd, 3.And the Hypertension incidence in China in Recent Years crowd is between 24%-27%.Hypertension is suffered from
The palsy of person/heart infarction disease rates are 5: 1.
The appearance of above-mentioned symptom be mainly people's living standard improve while, caused by human body own metabolism function it is disorderly
Disorderly, it is closely related with diet.Cerebrovascular morbidity and mortality could be reduced by being effectively improved cardio and vascular function.It is existing《System
The standby fermentation composition and preparation method for being suitable for cardiovascular and cerebrovascular diseases conditioning and its routine servicing effect plant enzyme》(Chinese patent Shen
Please number CN201710233356.3), mainly by 3~22 parts of functional oligose, 0.1~5 part of probiotics and Chinese medical extract
0.01~10 part of composition;Chinese medical extract is extracted by the raw material of following parts by weight:0.3~2 part of matrimony vine, 0.5~3 part
Mulberries, 0.1~1.6 part of sea-buckthorn, 0.5~3 part of pueraria lobata, 0.5~2 part of cassia seed, 0.1~0.8 part of aloe and 0.3
~2 parts of hawthorn.The fermentation composition is novel fermentation product, is to be used to prepare ferment " fermentation bacterium bag ", which uses
It is convenient, suitable for the industrialized production of all kinds of plant enzymes.《The preparation of the heart, cerebrovascular metabolic function plant enzyme beverage can be improved
Method》(Chinese Patent Application No. CN201310240616.1) takes malt, rice sprout, pueraria lobata, Radix Notoginseng, Radix Salviae Miltiorrhizae, Cortex Eucommiae, Rhizoma Chuanxiong, prolongs
Recklessly, Radix Polygalae, ganoderma lucidum, RADIX POLYGONI MULTIFLORI PREPARATA, radix polygonati officinalis, Radix Astragali, dried orange peel, sophora flower, hawthorn, mulberries, cassia seed, Cortex Eucommiae, gynostemma pentaphylla etc. add water logging
Bubble, decoction, it is bad that extracting solution uses conventional heat reflux pressure to follow, and sugaring, peptone are concocted, sterilizing, and filtering, filtrate is nutrition
Liquid;Nutrient solution connects prebiotic strain for 30 DEG C in fermentation tank, divides fourth phase mixed fermentation, and quality testing obtains drink.The present invention is with a variety of plants
Object is Solution culture method base, using a variety of compound probiotics as conversion tool, using multistage deep layer liquid state fermentation, in the raw material that can degrade
Venomous injurant, form new active constituent, release nutrients therein element, generate carbohydrase, egg during the fermentation
The active ingredients such as white enzyme, retain original active material, phytic acid are become functional lactate and acetic acid, insoluble fibre becomes
Soluble dietary fiber can improve body metabolism disorder, prevent Cardial or cerebral vascular diseases, it is high to reduce by three.
Invention content
The purpose of the present invention is be directed to above-mentioned present situation, it is desirable to provide after one kind is by rhizopus, red yeast rice bacterium composite fermentation,
Can improve original plant open it is strongly fragrant disappear stagnant, blood circulation and channel invigorating the effect of, improve human metabolism function to reach, prevent high blood
Fat, hypercoagulable blood, hyperglycemia, hypertension, artery sclerosis and cardiovascular and cerebrovascular disease, and a kind of improvement heart and brain blood that can be taken for a long time
The preparation method of pipe Chinese herbal medicine composite enzyme drink.
The embodiment of the object of the invention is a kind of preparation side for improving cardiovascular and cerebrovascular Chinese herbal medicine composite enzyme drink
Method is as follows:
1) raw material is cleaned;
2) raw material extracts, and will clean, treated 20-30 grams of pueraria lobata, 10-20 grams of hawthorn, 5-10 grams of lotus leaf, peach kernel 10-
15 grams, 10-15 grams of safflower, 10-15 grams of matrimony vine, 10-15 grams of chrysanthemum, 15-20 grams of mulberry fruit, 5-10 grams of dried orange peel, 5-10 grams of malt,
It is placed in extractor, adds water to more than 10 times of amounts of raw material weight, raw material is made to be fully immersed in water, heat water temperature to 60 DEG C,
It impregnates 6 hours, is again heated to 100 DEG C or more, after decocting 30-50 minutes, decoction liquor is filtered out, is added water in 1: 8 ratio
Decoct primary, decoction liquor merging twice;15-20 times of raw material weight is added water to, raw material is made to be fully immersed in water, water temperature rises to
55 DEG C -60 DEG C, 10-15h is impregnated, is again heated to 100 DEG C or more, extracts 50-60min;
3) extracting solution of step 2) is placed in ceramic cylinder with cover, the brown sugar of its quality 10-25% is added to mix 105 DEG C of high temperature
Sterilizing 40 minutes, filtering, filtrate is nutrient solution;
4) culture solution obtained by step 3) is put and 30-32 DEG C is cooled in fermentation tank, inoculation 3-5g rhizopus, 8-10g are red
Bent rice strain, rear to be sealed by fermentation 3-5 months, fermentation temperature is for 35-37 DEG C to get the improvement compound ferment of cardiovascular and cerebrovascular Chinese herbal medicine
Plain drink.
The present invention uses pueraria lobata, hawthorn, lotus leaf, peach kernel, safflower, matrimony vine, chrysanthemum, mulberry fruit, dried orange peel, malt as nutrient solution
Culture medium, using rhizopus and red yeast rice bacterium composite fermentation as conversion tool, using traditional deep layer liquid-state fermentation technology, can degrade original
Venomous injurant in material forms new active constituent, retains original active material, improve original plant open it is strongly fragrant disappear it is stagnant,
The effect of blood circulation and channel invigorating, safe and non-toxic, gained drink is the metabolite after pure natural fermentation, can effectively improve body metabolism work(
Can, prevention hyperlipidemia, hypercoagulable blood, hyperglycemia, hypertension, artery sclerosis and cardiovascular and cerebrovascular disease.
Specific embodiment
The present invention uses pueraria lobata, hawthorn, lotus leaf, peach kernel, safflower, matrimony vine, chrysanthemum, mulberry fruit, dried orange peel, malt as raw material,
It soaks, decoct, decoction liquor cryogenic vacuum is concentrated under reduced pressure, and sterilizing, filtering, filtrate is nutrient solution;Nutrient solution is placed in extractor
In, brown sugar is added to be uniformly mixed to obtain culture solution;Culture solution is put in fermentation tank and is cooled down, inoculation rhizopus, red yeast rice strain, rear sealing hair
Ferment 3-5 months, fermentation temperature is for 35-37 DEG C to get improvement cardiovascular and cerebrovascular Chinese herbal medicine composite enzyme drink.
The present invention is commercial product using rhizopus and red yeast rice strain composite fermentation, rhizopus, red yeast rice bacterium.Red yeast rice
Haematochrome can be generated, be various nontoxic dyeing foods and beverage additive color agent, be traditional a kind of beneficial to human body body and mind in China and
Harmless healthy food.Head mold can also generate a small amount of organic acid (such as lactic acid) in saccharifying.Pueraria lobata, hawthorn, lotus leaf, peach
Benevolence, safflower, matrimony vine, chrysanthemum, mulberry fruit, dried orange peel, malt are through rhizopus and red yeast rice bacterium composite fermentation, in anaerobic environment condition
Under, carbohydrase can be generated;Gained drink is the metabolite after pure natural fermentation, safe and non-toxic without any preservative, can
Achieve the effect that out the strongly fragrant stagnant, blood circulation and channel invigorating that disappears.
The present invention is described in detail with specific embodiment below.
Embodiment 1:
1) raw material is cleaned, rejects substandard products, poor products, not genuine kind;It is in order to ensure product quality, the qualification cleaned is high-quality
Raw material according to the different purposes of product, according to Chinese medicine preparation specification, is refined using distinct methods.
2) raw material extracts, and weighs 30 grams of pueraria lobata, 20 grams of hawthorn, 10 grams of lotus leaf, 15 grams of peach kernel, 15 grams of safflower, matrimony vine 15
Gram, 15 grams of chrysanthemum, 20 grams of mulberry fruit, 10 grams of dried orange peel, 10 grams of malt, be placed in extractor, add water to 10 times of raw material weight amounts with
On, raw material is made to be fully immersed in water, heating water temperature is impregnated 6 hours to 60 DEG C, is again heated to 100 DEG C or more, decocts 30-50
After minute, decoction liquor is filtered out, adds water decoction once in 1: 8 ratio, decoction liquor merges twice;Add water to raw material weight
15-20 times, raw material is made to be fully immersed in water, water temperature rises to 55 DEG C -60 DEG C, impregnates 10-15h, be again heated to 100 DEG C with
On, extract 50-60min;
3) extracting solution of step 2) is placed in ceramic cylinder with cover, the brown sugar of its quality 25% is added to mix 105 DEG C of high temperature and is gone out
Bacterium 40 minutes, filtering, filtrate is nutrient solution;
4) culture solution obtained by step 3) is put and 30-32 DEG C is cooled in fermentation tank, inoculation 3-5g rhizopus, 8-10g are red
Bent rice strain, rear to be sealed by fermentation 3-5 months, fermentation temperature is for 35-37 DEG C to get the improvement compound ferment of cardiovascular and cerebrovascular Chinese herbal medicine
Plain drink.
Embodiment 2:With embodiment 1, the difference is that,
2) raw material extracts, and weighs 28 grams of pueraria lobata, 18 grams of hawthorn, 8 grams of lotus leaf, 13 grams of peach kernel, 13 grams of safflower, matrimony vine 13
Gram, 13 grams of chrysanthemum, 18 grams of mulberry fruit, 8 grams of dried orange peel, 8 grams of malt, be placed in extractor, add water to more than 8 times of raw material weight amounts,
Raw material is made to be fully immersed in water, heating water temperature is impregnated 6 hours to 60 DEG C, is again heated to 100 DEG C or more, is decocted 30-50 minutes
Afterwards, decoction liquor is filtered out, adds water decoction once in 1: 8 ratio, decoction liquor merges twice;Add water to raw material weight
15-20 times, raw material is made to be fully immersed in water, water temperature rises to 55 DEG C -60 DEG C, impregnates 10-15h, is again heated to 100 DEG C or more,
Extract 50-60min;
3) extracting solution of step 2) is placed in ceramic cylinder with cover, the brown sugar of its quality 20% is added to mix 105 DEG C of high temperature and is gone out
Bacterium 40 minutes, filtering, filtrate is nutrient solution;
4) culture solution obtained by step 3) is put and 30-32 DEG C is cooled in fermentation tank, inoculation 3-5g rhizopus, 8-10g are red
Bent rice strain, rear to be sealed by fermentation 3-5 months, fermentation temperature is for 35-37 DEG C to get the improvement compound ferment of cardiovascular and cerebrovascular Chinese herbal medicine
Plain drink.
Embodiment 3:With embodiment 1, the difference is that,
2) raw material extracts, and weighs 26 grams of pueraria lobata, 16 grams of hawthorn, 6 grams of lotus leaf, 13 grams of peach kernel, 13 grams of safflower, matrimony vine 13
Gram, 13 grams of chrysanthemum, 18 grams of mulberry fruit, 8 grams of dried orange peel, 8 grams of malt, be placed in extractor, add water to more than 8 times of raw material weight amounts,
Raw material is made to be fully immersed in water, heating water temperature is impregnated 6 hours to 60 DEG C, is again heated to 100 DEG C or more, is decocted 30-50 minutes
Afterwards, decoction liquor is filtered out, adds water decoction once in 1: 8 ratio, decoction liquor merges twice;Add water to raw material weight
15-20 times, raw material is made to be fully immersed in water, water temperature rises to 55 DEG C -60 DEG C, impregnates 10-15h, is again heated to 100 DEG C or more,
Extract 50-60min;
3) extracting solution of step 2) is placed in ceramic cylinder with cover, the brown sugar of its quality 15% is added to mix 105 DEG C of high temperature and is gone out
Bacterium 40 minutes, filtering, filtrate is nutrient solution;
4) culture solution obtained by step 3) is put and 30-32 DEG C is cooled in fermentation tank, inoculation 3-5g rhizopus, 8-10g are red
Bent rice strain, rear to be sealed by fermentation 3-5 months, fermentation temperature is for 35-37 DEG C to get the improvement compound ferment of cardiovascular and cerebrovascular Chinese herbal medicine
Plain drink.
Embodiment 4:With embodiment 1, the difference is that,
2) raw material extracts, and weighs 23 grams of pueraria lobata, 13 grams of hawthorn, 6 grams of lotus leaf, 12 grams of peach kernel, 12 grams of safflower, matrimony vine 12
Gram, 12 grams of chrysanthemum, 18 grams of mulberry fruit, 6 grams of dried orange peel, 6 grams of malt, be placed in extractor, add water to more than 8 times of raw material weight amounts,
Raw material is made to be fully immersed in water, heating water temperature is impregnated 6 hours to 60 DEG C, is again heated to 100 DEG C or more, is decocted 30-50 minutes
Afterwards, decoction liquor is filtered out, adds water decoction once in 1: 8 ratio, decoction liquor merges twice;Add water to raw material weight
15-20 times, raw material is made to be fully immersed in water, water temperature rises to 55 DEG C -60 DEG C, impregnates 10-15h, is again heated to 100 DEG C or more,
Extract 50-60min;
3) extracting solution of step 2) is placed in ceramic cylinder with cover, the brown sugar of its quality 10% is added to mix 105 DEG C of high temperature and is gone out
Bacterium 40 minutes, filtering, filtrate is nutrient solution;
4) culture solution obtained by step 3) is put and 30-32 DEG C is cooled in fermentation tank, inoculation 3-5g rhizopus, 8-10g are red
Bent rice strain, rear to be sealed by fermentation 3-5 months, fermentation temperature is for 35-37 DEG C to get the improvement compound ferment of cardiovascular and cerebrovascular Chinese herbal medicine
Plain drink.
Embodiment 5:With embodiment 1, the difference is that,
2) raw material extracts, and weighs 20 grams of pueraria lobata, 10 grams of hawthorn, 5 grams of lotus leaf, 10 grams of peach kernel, 10 grams of safflower, matrimony vine 10
Gram, 10 grams of chrysanthemum, 15 grams of mulberry fruit, 5 grams of dried orange peel, 5 grams of malt, be placed in extractor, add water to more than 8 times of raw material weight amounts,
Raw material is made to be fully immersed in water, heating water temperature is impregnated 6 hours to 60 DEG C, is again heated to 100 DEG C or more, is decocted 30-50 minutes
Afterwards, decoction liquor is filtered out, adds water decoction once in 1: 8 ratio, decoction liquor merges twice;Add water to raw material weight
15-20 times, raw material is made to be fully immersed in water, water temperature rises to 55 DEG C -60 DEG C, impregnates 10-15h, is again heated to 100 DEG C or more,
Extract 50-60min;
3) extracting solution of step 2) is placed in ceramic cylinder with cover, the brown sugar of its quality 10% is added to mix 105 DEG C of high temperature and is gone out
Bacterium 40 minutes, filtering, filtrate is nutrient solution;
4) culture solution obtained by step 3) is put and 30-32 DEG C is cooled in fermentation tank, inoculation 3-5g rhizopus, 8-10g are red
Bent rice strain, rear to be sealed by fermentation 3-5 months, fermentation temperature is for 35-37 DEG C to get the improvement compound ferment of cardiovascular and cerebrovascular Chinese herbal medicine
Plain drink.
Claims (2)
1. a kind of preparation method for improving cardiovascular and cerebrovascular Chinese herbal medicine composite enzyme drink, it is characterised in that specific steps are such as
Under:
1) raw material is cleaned;
2) raw material extracts, will clean, treated raw material pueraria lobata, hawthorn, lotus leaf, peach kernel, safflower, matrimony vine, chrysanthemum, mulberry fruit,
Dried orange peel, malt are placed in extractor, add water to more than 10 times of amounts of raw material weight, raw material is made to be fully immersed in water, heat water
Temperature is impregnated 6 hours to 60 DEG C, is again heated to 100 DEG C or more, and after decocting 30-50 minutes, decoction liquor is filtered out, by 1: 8 ratio
Example adds water decoction once, and decoction liquor merges twice;15-20 times of raw material weight is added water to, raw material is made to be fully immersed in water,
Water temperature rises to 55 DEG C -60 DEG C, impregnates 10-15h, is again heated to 100 DEG C or more, extracts 50-60min;
3) extracting solution of step 2) is placed in ceramic cylinder with cover, the brown sugar of its quality 10-25% is added to mix 105 DEG C of high-temperature sterilizations
40 minutes, filtering, filtrate was nutrient solution;
4) culture solution obtained by step 3) is put and 30-32 DEG C is cooled in fermentation tank, inoculation 3-5g rhizopus, 8-10g red yeast rices
Strain, rear to be sealed by fermentation 3-5 months, fermentation temperature is for 35-37 DEG C to get improvement cardiovascular and cerebrovascular Chinese herbal medicine composite enzyme drink
Product.
2. a kind of preparation method for improving cardiovascular and cerebrovascular Chinese herbal medicine composite enzyme drink according to claim 1,
It is characterized in that:It is by pueraria lobata, hawthorn, lotus leaf, peach kernel, safflower, matrimony vine, chrysanthemum, mulberry fruit, dried orange peel, wheat that step 1), which cleans raw material,
It is fully immersed in water after bud screening, removal of impurities, heating water temperature is impregnated 6 hours to 60 DEG C.
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CN110772596A (en) * | 2019-11-28 | 2020-02-11 | 西安荷默奇医药科技有限公司 | A functional food, TAOHUAJING, prepared from Chinese medicinal materials, and its quality control and component analysis method |
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Application publication date: 20180608 |