CN108096473B

CN108096473B - Medicinal incense for conditioning gynecopathy and processing technology thereof

Info

Publication number: CN108096473B
Application number: CN201711382846.6A
Authority: CN
Inventors: 朱雪明; 王姚; 阮小军
Original assignee: Jiaxing Softter Biotechnology Co ltd
Current assignee: JIAXING SOFTTER BIOTECHNOLOGY Co.,Ltd.
Priority date: 2017-12-20
Filing date: 2017-12-20
Publication date: 2021-02-23
Anticipated expiration: 2037-12-20
Also published as: CN108096473A

Abstract

The invention discloses a medicinal incense for conditioning gynecopathy, which is prepared from the following raw materials: motherwort, salvia miltiorrhiza, angelica, ligusticum wallichii, astragalus mongholicus, eclipta alba, rhizoma cyperi, bighead atractylodes rhizome, radix paeoniae alba, rhizoma gastrodiae, cinnamon, poria cocos, sandalwood, poplar powder, water and a binder. The medicine fragrance for conditioning gynecopathy, prepared according to the modern traditional Chinese medicine compatibility theory, can directly enter the focus, has the effects of tonifying qi and nourishing blood, promoting blood circulation to restore menstrual flow, removing blood stasis and relieving pain, has a good conditioning effect on difficult and complicated gynecopathy, does not have toxic or side effect, is green and environment-friendly, and is convenient to use.

Description

Medicinal incense for conditioning gynecopathy and processing technology thereof

Technical Field

The invention relates to a medicinal incense capable of conditioning gynecopathy.

Background

The raw materials of traditional medicated incense are generally made of incense, wood powder, binder and additive materials. Wherein the aromatic comprises natural perfume and some Chinese medicinal materials. The existing incense on the market is mainly divided into reading incense, epidemic-dispelling incense, pestilence-dispelling incense, air-purifying incense, health-preserving health-care incense for regulating blood pressure and the like. At present, no medicine incense capable of conditioning gynecological diseases exists.

The Chinese medicine culture is a treasure in China, and the history of treating gynecological diseases by using the Chinese medicine is long. Difficult miscellaneous diseases and chronic diseases of gynecology can affect the normal life of people, but can not be cured radically. The traditional Chinese medicine for treating gynecological diseases starts from the whole view, soothes liver and regulates qi, strengthens body resistance, promotes blood circulation to remove blood stasis, softens hard lumps and dissipates nodes, clears away heat and toxic materials, comprehensively regulates endocrine to promote blood circulation and activate blood, activates viscera, is the basis of main and collateral channels, uses qi and blood, is the material basis of the body, is the source of qi and blood generation, plays the roles of generation, general control and operation of branch vessel blood, regulation of blood and balance, and uses qi as the motive power of blood. Blood is the material basis of menstruation, and if the viscera function is disordered, the circulation of qi and blood will be affected, and the blood and sea function will be affected, which may cause various gynecological diseases, such as ovarian cyst, etc. The traditional Chinese medicine treatment can avoid psychological pressure and mental burden brought to patients by operation, regulate endocrine, enhance immunity and the like, is convenient to take, does not need operation, does not hurt vitality, has small pain risk, low cost and quick effect. The traditional Chinese medicinal materials are prepared into medicinal incense, so that the toxic and side effects caused by oral administration of the traditional Chinese medicines are reduced, the traditional Chinese medicine is convenient to use frequently in daily life, and the traditional Chinese medicine not only has a treatment effect, but also has the effects of purifying air and preserving health.

Generally, the incense medicine and the wood powder in the medicine incense are generally powdery and are relatively loose, so that the incense medicine and the wood powder are not easy to integrate, and materials with a binding effect need to be added. The prior medicinal incense product also uses chemical bonding materials, which not only reduces the quality of the medicinal incense, but also generates substances which are unfavorable to human bodies in the burning process of the medicinal incense. The medicine incense formula of the invention is scientific and reasonable, regulates the qi and blood circulation of women and has good regulation effect on difficult and complicated gynecological diseases. The invention has no toxic or side effect on the medicine fragrance, does not add chemical adhesive, and is green and environment-friendly.

Disclosure of Invention

The invention provides a medicinal incense for conditioning gynecopathy and a processing technology thereof. The invention adopts the following technical scheme:

the medicine incense for conditioning gynecological diseases is prepared from the following raw materials in parts by weight:

2.5-5 parts of motherwort, 3-6 parts of salvia miltiorrhiza, 2-4 parts of angelica, 1.5-3 parts of ligusticum wallichii, 2-4 parts of astragalus mongholicus, 0.5-1 part of eclipta alba, 1-3 parts of rhizoma cyperi, 1-3 parts of bighead atractylodes rhizome, 1.5-4.5 parts of radix paeoniae alba, 0.3-1 part of gastrodia elata, 0.2-0.6 part of cinnamon, 1.5-3 parts of poria cocos, 0.5-1.5 parts of sandalwood, 3-9 parts of poplar powder, 10-30 parts of water and 2-6 parts of bonding material.

The invention provides a processing technology of the medicinal incense for conditioning gynecopathy, which comprises the following steps: weighing the raw materials in parts by weight, respectively drying motherwort, salvia miltiorrhiza, angelica, ligusticum wallichii, astragalus mongholicus, eclipta alba, rhizoma cyperi, bighead atractylodes rhizome, radix paeoniae alba, gastrodia elata, cinnamon, poria cocos and sandalwood at 45-65 ℃ for 6-12 hours, crushing and screening by a 50-80-mesh sieve, mixing the crushed raw materials, putting the raw materials into a stirrer, adding poplar powder, water and a binding material, stirring for 30-90 minutes at 45-65 ℃ at a rotating speed of 200 revolutions per minute to obtain a mixture, and pressing, forming and drying the mixture to obtain the finished medicinal incense.

Preferably, the invention provides a processing technology of the medicinal incense for conditioning gynecological diseases, which comprises the following steps: weighing the raw materials according to the weight part, respectively drying motherwort, salvia miltiorrhiza, angelica, ligusticum wallichii, astragalus mongholicus, eclipta alba, rhizoma cyperi, bighead atractylodes rhizome, radix paeoniae alba, gastrodia elata, cinnamon, poria cocos and sandalwood at 45-65 ℃ for 6-12 hours, crushing and sieving with a 50-80-mesh sieve, mixing the crushed raw materials, putting the raw materials into a stirrer, adding poplar powder, water and a binding material, stirring at 45-65 ℃ for 30-90 minutes at a rotation speed of 200 revolutions per minute, obtaining a mixture, pressing the mixture into incense with the diameter of 4.0-4.2mm, coiling into disk-shaped incense with the diameter of 12-15cm and the weight of 25-30g, drying at 45-55 ℃ to obtain the finished incense with the water content of 10-12%.

2.5-5 parts of motherwort, 3-6 parts of salvia miltiorrhiza, 2-4 parts of angelica, 1.5-3 parts of ligusticum wallichii, 2-4 parts of astragalus mongholicus, 0.5-1 part of eclipta alba, 1-3 parts of rhizoma cyperi, 1-3 parts of bighead atractylodes rhizome, 1.5-4.5 parts of radix paeoniae alba, 0.3-1 part of gastrodia elata, 0.2-0.6 part of cinnamon, 1.5-3 parts of poria cocos, 0.5-1.5 parts of sandalwood, 3-9 parts of modified poplar powder, 10-30 parts of water and 2-6 parts of bonding material.

The invention also provides a processing technology of the medicinal incense for conditioning gynecological diseases, which comprises the following steps: weighing the raw materials in parts by weight, respectively drying motherwort, salvia miltiorrhiza, angelica, ligusticum wallichii, astragalus mongholicus, eclipta alba, rhizoma cyperi, bighead atractylodes rhizome, radix paeoniae alba, gastrodia elata, cinnamon, poria cocos and sandalwood at 45-65 ℃ for 6-12 hours, crushing and screening by a 50-80-mesh sieve, mixing the crushed raw materials, putting the raw materials into a stirrer, adding modified poplar powder, water and a binding material, stirring for 30-90 minutes at 45-65 ℃ at a rotating speed of 400 revolutions per minute to obtain a mixture, and pressing, molding and drying the mixture to obtain the finished medicinal incense.

Preferably, the invention also provides a processing technology of the medicinal incense for conditioning gynecological diseases, which comprises the following steps: weighing the raw materials according to the weight part, respectively drying motherwort, salvia miltiorrhiza, angelica, ligusticum wallichii, astragalus mongholicus, eclipta alba, rhizoma cyperi, bighead atractylodes rhizome, radix paeoniae alba, gastrodia elata, cinnamon, poria cocos and sandalwood at 45-65 ℃ for 6-12 hours, crushing and sieving by a 50-80-mesh sieve, mixing the crushed raw materials, putting the raw materials into a stirrer, adding modified poplar powder, water and a bonding material, stirring at 45-65 ℃ for 30-90 minutes at a rotation speed of 400 revolutions per minute with 200 materials, obtaining a mixture, pressing the mixture into incense with the diameter of 4.0-4.2mm, coiling into disk-shaped incense with the diameter of 12-15cm and the weight of 25-30g, drying at 45-55 ℃ to obtain the finished incense with the water content of 10-12%.

Preferably, the preparation method of the modified poplar powder comprises the steps of mixing 25-75g of poplar powder and 10-40mL of ionic liquid, putting the mixture into a stirrer, stirring the mixture for 30-50 minutes at the temperature of 40-45 ℃ and at the rotating speed of 400 rpm, discharging the mixture, sealing the mixture, placing the mixture in a drying box at the temperature of 70-85 ℃ for 30-60 minutes to obtain a mixture A, adding the mixture A into 250g of water at the temperature of 120-45 ℃, stirring the mixture for 30-60 minutes at the rotating speed of 300 rpm at the temperature of 100-45 ℃, filtering the mixture, washing the filtered precipitate with 30-60g of acetone and 45-90g of ethanol, and drying the precipitate for 12-24 hours at the temperature of 40-55 ℃ to obtain the modified poplar powder; the ionic liquid is (1-butyl-3-methylimidazole) chloride and 1-butylpyridinium chloride in a mass ratio of (1-4): (1-4).

More preferably, the preparation method of the modified poplar powder comprises the steps of mixing 25-75g of poplar powder and 10-40mL of ionic liquid, putting the mixture into a stirrer, stirring the mixture for 30-50 minutes at the temperature of 40-45 ℃ and at the rotation speed of 200-400 rpm, discharging the material, sealing the material, placing the mixture in a drying box at the temperature of 70-85 ℃ for 30-60 minutes to obtain a mixture A, adding the mixture A into 250g of water at the temperature of 120-45 ℃, stirring the mixture for 30-60 minutes at the rotation speed of 100-300 rpm, filtering the mixture, washing the filtered precipitate with 30-60g of acetone and 45-90g of ethanol, drying the washed precipitate at the temperature of 40-55 ℃ for 12-24 hours to obtain a mixture B, adjusting the pH value of 15-45g of an ethanol aqueous solution with the mass fraction of 85-95% to 3-4 by using glacial acetic acid, adding 0.85-1.7g of modifier I, uniformly mixing to obtain a mixed solution C, uniformly spraying all the mixed solution C on the surface of the mixture B, putting the mixture B into a stirrer, stirring for 50-100 minutes at the temperature of 60-75 ℃ at the rotating speed of 500 revolutions per minute, discharging, and drying for 24-48 hours at the temperature of 40-60 ℃ to obtain modified poplar powder; the ionic liquid is (1-butyl-3-methylimidazole) chloride and 1-butylpyridinium chloride in a mass ratio of (1-4): the mixture of (1-4); the modifier I is one or a mixture of more of oleamide, vinyl trimethoxy silane and isopropyl tri (dioctyl pyrophosphato acyloxy) titanate.

Further preferably, the ionic liquid is a mixture of (1-butyl-3-methylimidazole) chloride and 1-butylpyridinium chloride in a mass ratio of 1: 4.

Further preferably, the modifier I is vinyltrimethoxysilane.

Preferably, the binder is one or a mixture of sunflower seed meal adhesive, guar gum and carrageenan.

Further preferably, the binding material is a sunflower seed meal adhesive, and the preparation method of the sunflower seed meal adhesive comprises the steps of uniformly mixing 120-240 parts of sunflower seed meal powder, 200-400 parts of water, 12-18 parts of modifier II and 8-12 parts of potassium hydroxide, heating to 55-75 ℃, stirring at the temperature of 55-75 ℃ for 3.5-7 hours at the rotating speed of 200-300 revolutions per minute, naturally cooling to 30-45 ℃, adding 11.5-23 parts of glutaraldehyde, stirring at the temperature of 30-45 ℃ at the rotating speed of 250-400 revolutions per minute for 25-45 minutes to obtain the sunflower seed meal adhesive; the modifier II is one or a mixture of polyvinyl alcohol, sodium dodecyl benzene sulfonate and urea.

Further preferably, the modifier II is a mixture of polyvinyl alcohol and sodium dodecyl benzene sulfonate in a mass ratio of (3-5) to (1-2).

Further preferably, the modifier II is a mixture of polyvinyl alcohol and sodium dodecyl benzene sulfonate in a mass ratio of 3: 2.

The medicine fragrance for conditioning gynecopathy, prepared according to the modern traditional Chinese medicine compatibility theory, can directly enter the focus, has the effects of tonifying qi and nourishing blood, promoting blood circulation to restore menstrual flow, removing blood stasis and relieving pain, has a good conditioning effect on difficult and complicated gynecopathy, does not have toxic or side effect, is green and environment-friendly, and is convenient to use.

On the basis of the common knowledge in the field, the above preferred conditions can be combined randomly to obtain the preferred embodiments of the invention.

Detailed Description

The invention is further illustrated by the following examples, which are not intended to limit the scope of the invention. The experimental methods without specifying specific conditions in the following examples were selected according to the conventional methods and conditions, or according to the commercial instructions.

In the following examples, the main raw materials and equipment used were as follows:

motherwort, Latin school name: leonurus artemisia (Laur.) S.Y.Hu F has the functions of inducing diuresis to reduce edema and contracting uterus, is a main medicine for treating gynecopathy by doctors of all generations, and uses overground dried whole herb of motherwort.

Salvia miltiorrhiza, a dried root of Salvia miltiorrhiza bge, has effects of promoting blood circulation, removing blood stasis, dredging channels, relieving pain, clearing heart fire, relieving restlessness, cooling blood, and resolving carbuncle.

Angelica sinensis, a dried root of Angelica sinensis (Oliv.) Diels of Umbelliferae, has effects of replenishing blood and blood, regulating menstruation, relieving pain, moistening dryness, smoothing intestine, and resisting cancer.

Rhizoma Ligustici Chuanxiong is dried rhizome of Ligusticum chuanxiong Hort of Umbelliferae, pungent and warm. It enters liver, gallbladder and pericardium channels, and has effects of promoting blood circulation, activating qi-flowing, dispelling pathogenic wind and relieving pain.

Radix astragali, specifically dried root of Mongolian radix astragali (Labin: Astragalus membranaceus (Fish) Bungevar. Mongholicus (Bunge) Hsiao) is used for treating short breath, palpitation, asthenia, collapse, spontaneous perspiration, night sweat, edema due to asthenia, chronic nephritis, chronic diarrhea, proctoptosis, uterine prolapse, carbuncle, ulcer, and unhealed sore.

Eclipta alba, an overground dry whole plant of Eclipta prostrata (Latin chemical name) of herbaceous plants of Compositae, has the effects of tonifying liver and kidney, stopping bleeding and cooling blood.

Cyperus rotundus, Latin scientific name: cyperus rotundus L, a dried rhizome of Cyperus rotundus L.of Cyperaceae family, is used for treating stagnation of qi due to depression of the liver, distending pain in chest and hypochondrium, hernia pain, breast distending pain, qi stagnation in spleen and stomach, abdominal fullness and stuffiness, fullness and pain, irregular menstruation, amenorrhea and dysmenorrhea.

Atractylodis rhizoma, dried rhizome of Atractylodes macrocephala Koidz of Compositae, has effects of invigorating spleen and invigorating qi, eliminating dampness and promoting diuresis, arresting sweating, and preventing miscarriage, and can be used for treating spleen deficiency and anorexia, abdominal distention and diarrhea, phlegm retention and palpitation, edema, spontaneous perspiration, and threatened abortion.

White peony root, latin scientific name: cynanchum otophyllum, a plant of Paeonia of Ranunculaceae, is a dried root of Paeonia lactiflora pall of Ranunculaceae, and has effects of suppressing hyperactive liver, relieving pain, nourishing blood, regulating menstruation, astringing yin, and arresting sweating. Can be used for treating headache, vertigo, hypochondriac pain, abdominal pain, limb spasm and pain, blood deficiency, sallow complexion, and menoxenia.

Gastrodia elata (Gastrodia elata Bl.) of Orchidaceae family is used for calming liver, calming endogenous wind and relieving spasm, and belongs to the category of liver-calming and wind-calming herbs.

Cinnamon, latin scientific name: cinnamomum cassia Presl is dry bark of Cinnamomum cassia of Lauraceae, and has effects of invigorating primordial qi, warming spleen and stomach, removing cold accumulation, and promoting blood circulation.

Poria is dried sclerotium of Wolf (Schw.) Wolf of Poria cocos (belonging to Polyporaceae), and can be used for treating edema, oliguria, phlegm and fluid retention, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.

Lignum Santali albi is the heartwood of Santalbum L.

Poplar powder is prepared from Populus alba (Latin chemical name: Populus alba L) powder with particle size of 80 mesh.

The sunflower seed meal powder is a substance obtained by squeezing oil from sunflower seeds by a direct leaching method, and meets the first-class standard in GB/T22463-2008, and the particle size is 50 meshes.

Chloro (1-butyl-3-methylimidazole), CAS No.: 79917-90-1.

1-butylpyridinium chloride, CAS No.: 1124-64-7.

Acetone, CAS No.: 67-64-1.

Ethanol, CAS No.: 64-17-5.

Glacial acetic acid, CAS No.: 64-19-7.

Oleamide, CAS number: 301-02-0.

Vinyltrimethoxysilane, CAS No.: 2768-02-7.

Isopropyl tris (dioctyl pyrophosphato acyloxy) titanate, CAS No.: 67691-13-8.

Potassium hydroxide, CAS No.: 1310-58-3.

Glutaraldehyde, CAS number: 111-30-8.

Polyvinyl alcohol, average degree of polymerization 2400-.

Sodium dodecylbenzenesulfonate, CAS No.: 25155-30-0.

Urea, CAS No.: 57-13-6.

Guar gum, CAS No.: 9000-30-0.

In the following examples, the test methods used are as follows:

and (3) testing the burning time: the incense charges prepared in the examples were taken, ignited, and the time taken for the incense charges to burn out completely was recorded, repeated 5 times, and averaged.

And (3) testing the breaking strength: the test was carried out according to the regulations of GB/T18416-2009.

The invention is further illustrated by the following examples, in which the parts are by weight unless otherwise specified.

Example 1

The medicinal incense for conditioning gynecopathy is prepared from the following raw materials in parts by weight:

2.5 parts of motherwort, 3 parts of salvia miltiorrhiza, 2 parts of angelica, 1.5 parts of ligusticum wallichii, 2 parts of astragalus mongholicus, 0.5 part of eclipta alba, 1 part of rhizoma cyperi, 1 part of bighead atractylodes rhizome, 1.5 parts of radix paeoniae alba, 0.3 part of rhizoma gastrodiae, 0.2 part of cinnamon, 1.5 parts of poria cocos, 0.5 part of sandalwood, 3 parts of poplar powder, 18 parts of water and 2 parts of bonding material.

The binding material is guar gum.

The processing technology of the medicine incense for conditioning gynecopathy is as follows: weighing the raw materials in parts by weight, respectively drying motherwort, salvia miltiorrhiza, angelica, ligusticum wallichii, astragalus mongholicus, eclipta alba, rhizoma cyperi, bighead atractylodes rhizome, radix paeoniae alba, gastrodia elata, cinnamon, poria cocos and sandalwood at 45 ℃, crushing and sieving by a 80-mesh sieve, mixing the crushed raw materials, putting the raw materials into a stirrer, adding poplar powder, water and a bonding material, stirring for 30 minutes at 45 ℃ at a rotating speed of 200 revolutions per minute to obtain a mixture, pressing the mixture into incense with the diameter of 4.0mm, then coiling into disk-shaped incense with the diameter of 12cm and the weight of 25g, and drying at 45 ℃ to obtain the finished incense with the water content of 10%.

Example 2

2.5 parts of motherwort, 3 parts of salvia miltiorrhiza, 2 parts of angelica, 1.5 parts of ligusticum wallichii, 2 parts of astragalus mongholicus, 0.5 part of eclipta alba, 1 part of rhizoma cyperi, 1 part of bighead atractylodes rhizome, 1.5 parts of radix paeoniae alba, 0.3 part of rhizoma gastrodiae, 0.2 part of cinnamon, 1.5 parts of poria cocos, 0.5 part of sandalwood, 3 parts of modified poplar powder, 18 parts of water and 2 parts of bonding material.

The preparation method of the modified poplar wood powder comprises the following steps: mixing 25g of poplar powder and 10mL of ionic liquid, putting the mixture into a stirrer, stirring the mixture for 30 minutes at 40 ℃ at a rotating speed of 300 revolutions per minute, discharging and sealing the mixture, putting the mixture into a drying box at 70 ℃ for 30 minutes to obtain a mixture A, adding the mixture A into 120g of water, stirring the mixture for 30 minutes at 30 ℃ at a rotating speed of 100 revolutions per minute, sieving the mixture A by a 200-mesh sieve, washing a precipitate obtained by filtering the mixture by 30g of acetone and 45g of ethanol, and drying the precipitate for 12 hours at 40 ℃ to obtain modified poplar powder; the ionic liquid is a mixture of chlorinated (1-butyl-3-methylimidazole) and 1-butyl pyridine chloride according to a mass ratio of 4: 1.

The binding material is guar gum.

The processing technology of the medicine incense for conditioning gynecopathy is as follows: weighing the raw materials in parts by weight, respectively drying motherwort, salvia miltiorrhiza, angelica, ligusticum wallichii, astragalus mongholicus, eclipta alba, rhizoma cyperi, bighead atractylodes rhizome, radix paeoniae alba, rhizoma gastrodiae, cinnamon, poria cocos and sandalwood at 45 ℃, crushing and sieving by a 80-mesh sieve, mixing the crushed raw materials, putting the raw materials into a stirrer, adding modified poplar powder, water and a bonding material, stirring for 30 minutes at 45 ℃ at a rotating speed of 200 r/min to obtain a mixture, pressing the mixture into incense with the diameter of 4.0mm, coiling into disk-shaped incense with the diameter of 12cm and the weight of 25g, and drying at 45 ℃ to obtain the finished incense with the water content of 10%.

Example 3

Basically the same as example 2, except that, in this example 3, the modified poplar wood flour was prepared as follows: mixing 25g of poplar powder and 10mL of ionic liquid, putting the mixture into a stirrer, stirring the mixture for 30 minutes at 40 ℃ at a rotating speed of 300 revolutions per minute, discharging and sealing the mixture, putting the mixture into a drying box at 70 ℃ for 30 minutes to obtain a mixture A, adding the mixture A into 120g of water, stirring the mixture for 30 minutes at 30 ℃ at a rotating speed of 100 revolutions per minute, sieving the mixture A by a 200-mesh sieve, washing a precipitate obtained by filtering the mixture by 30g of acetone and 45g of ethanol, and drying the precipitate for 12 hours at 40 ℃ to obtain modified poplar powder; the ionic liquid is a mixture of chlorinated (1-butyl-3-methylimidazole) and 1-butyl pyridine chloride according to a mass ratio of 1: 1.

Example 4

Basically the same as example 2, except that, in this example 4, the modified poplar wood flour was prepared as follows: mixing 25g of poplar powder and 10mL of ionic liquid, putting the mixture into a stirrer, stirring the mixture for 30 minutes at 40 ℃ at a rotating speed of 300 revolutions per minute, discharging and sealing the mixture, putting the mixture into a drying box at 70 ℃ for 30 minutes to obtain a mixture A, adding the mixture A into 120g of water, stirring the mixture for 30 minutes at 30 ℃ at a rotating speed of 100 revolutions per minute, sieving the mixture A by a 200-mesh sieve, washing a precipitate obtained by filtering the mixture by 30g of acetone and 45g of ethanol, and drying the precipitate for 12 hours at 40 ℃ to obtain modified poplar powder; the ionic liquid is a mixture of chlorinated (1-butyl-3-methylimidazole) and 1-butyl pyridine chloride according to a mass ratio of 1: 4.

Example 5

The preparation method of the modified poplar wood powder comprises the following steps: mixing 25g poplar powder and 10mL ionic liquid, putting into a stirrer, stirring at 40 ℃ and 300 r/min for 30 minutes, discharging, sealing, putting into a drying box at 70 ℃ for 30 minutes to obtain a mixture A, adding the mixture A into 120g water, stirring at 30 ℃ and 100 r/min for 30 minutes, sieving with a 200-mesh sieve, washing the filtered precipitate with 30g acetone and 45g ethanol, drying at 40 ℃ for 12 hours to obtain a mixture B, adjusting the pH of 15g ethanol aqueous solution with the mass fraction of 95% to 3 with glacial acetic acid, adding 0.85g modifier I, mixing uniformly to obtain a mixed solution C, spraying all the mixed solution C onto the surface of the mixture B uniformly, putting into the stirrer, stirring at 60 ℃ and 300 r/min for 50 minutes, discharging, drying at 40 ℃ for 24 hours, obtaining modified poplar powder; the ionic liquid is a mixture of chlorinated (1-butyl-3-methylimidazole) and 1-butyl pyridine chloride according to a mass ratio of 1: 4; the modifier I is oleamide.

The binding material is guar gum.

Example 6

Essentially the same as example 5, except that in this example 6, modifier I is vinyltrimethoxysilane.

Example 7

Essentially the same as example 5, except that in this example 7, modifier I was isopropyltris (dioctylpyrophosphate) titanate.

Comparative example 1

Substantially the same as example 5 except that, in the present comparative example 1, the modified poplar wood flour was prepared as follows: adjusting the pH value of 15g of ethanol water solution with the mass fraction of 95% to 3 by using glacial acetic acid, adding 0.85g of modifier I to obtain a mixed solution, uniformly spraying the mixed solution on the surface of 25g of poplar powder, putting the mixture into a stirrer, stirring at the temperature of 60 ℃ and the rotating speed of 300 revolutions per minute for 50 minutes, discharging, and drying at the temperature of 40 ℃ for 24 hours to obtain modified poplar powder; the modifier I is vinyl trimethoxy silane.

Example 8

The preparation method of the modified poplar wood powder comprises the following steps: mixing 25g poplar powder and 10mL ionic liquid, putting into a stirrer, stirring at 40 ℃ and 300 r/min for 30 minutes, discharging, sealing, putting into a drying box at 70 ℃ for 30 minutes to obtain a mixture A, adding the mixture A into 120g water, stirring at 30 ℃ and 100 r/min for 30 minutes, sieving with a 200-mesh sieve, washing the filtered precipitate with 30g acetone and 45g ethanol, drying at 40 ℃ for 12 hours to obtain a mixture B, adjusting the pH of 15g ethanol aqueous solution with the mass fraction of 95% to 3 with glacial acetic acid, adding 0.85g modifier I, mixing uniformly to obtain a mixed solution C, spraying all the mixed solution C onto the surface of the mixture B uniformly, putting into the stirrer, stirring at 60 ℃ and 300 r/min for 50 minutes, discharging, drying at 40 ℃ for 24 hours, obtaining modified poplar powder; the ionic liquid is a mixture of chlorinated (1-butyl-3-methylimidazole) and 1-butyl pyridine chloride according to a mass ratio of 1: 4; the modifier I is vinyl trimethoxy silane.

The binding material is sunflower seed meal adhesive.

The preparation method of the sunflower seed meal adhesive comprises the following steps: uniformly mixing 120 parts of sunflower seed meal powder, 200 parts of water, 12 parts of modifier II and 8 parts of potassium hydroxide, heating to 55 ℃ at the speed of 2 ℃/min, stirring at the temperature of 55 ℃ at the rotating speed of 200 revolutions per minute for 3.5 hours, naturally cooling to 30 ℃, adding 11.5 parts of glutaraldehyde, and stirring at the temperature of 30 ℃ at the rotating speed of 250 revolutions per minute for 25 minutes to obtain the sunflower seed meal adhesive; and the modifier II is polyvinyl alcohol.

Example 9

Essentially the same as example 8, except that in this example 9, the sunflower seed meal adhesive was prepared as follows: uniformly mixing 120 parts of sunflower seed meal powder, 200 parts of water, 12 parts of modifier II and 8 parts of potassium hydroxide, heating to 55 ℃ at the speed of 2 ℃/min, stirring at the temperature of 55 ℃ at the rotating speed of 200 revolutions per minute for 3.5 hours, naturally cooling to 30 ℃, adding 11.5 parts of glutaraldehyde, and stirring at the temperature of 30 ℃ at the rotating speed of 250 revolutions per minute for 25 minutes to obtain the sunflower seed meal adhesive; the modifier II is sodium dodecyl benzene sulfonate.

Example 10

Basically the same as example 8, except that in this example 10, the sunflower seed meal adhesive was prepared as follows: uniformly mixing 120 parts of sunflower seed meal powder, 200 parts of water, 12 parts of modifier II and 8 parts of potassium hydroxide, heating to 55 ℃ at the speed of 2 ℃/min, stirring at the temperature of 55 ℃ at the rotating speed of 200 revolutions per minute for 3.5 hours, naturally cooling to 30 ℃, adding 11.5 parts of glutaraldehyde, and stirring at the temperature of 30 ℃ at the rotating speed of 250 revolutions per minute for 25 minutes to obtain the sunflower seed meal adhesive; the modifier II is urea.

Example 11

Essentially the same as example 8, except that in this example 11, the sunflower seed meal adhesive was prepared as follows: uniformly mixing 120 parts of sunflower seed meal powder, 200 parts of water, 12 parts of modifier II and 8 parts of potassium hydroxide, heating to 55 ℃ at the speed of 2 ℃/min, stirring at the temperature of 55 ℃ at the rotating speed of 200 revolutions per minute for 3.5 hours, naturally cooling to 30 ℃, adding 11.5 parts of glutaraldehyde, and stirring at the temperature of 30 ℃ at the rotating speed of 250 revolutions per minute for 25 minutes to obtain the sunflower seed meal adhesive; the modifier II is a mixture of polyvinyl alcohol and sodium dodecyl benzene sulfonate in a mass ratio of 3: 2.

The bending strength test result of this example 11 was 4.7N, and the burning time was 10.4 hours.

Test example 1

The invention has scientific formula, has the functions of benefiting qi and nourishing blood, promoting blood circulation to restore menstrual flow, removing blood stasis and relieving pain, is used for conditioning gynecological diseases, has obvious effect, does not have toxic or side effect and is convenient to use.

Plum red, which is 37 years old, has leucorrhea in lower abdominal pain, is applied with the medicine after repeated overshooting and washing, has little effect and is accompanied with external pruritus and pain in waist and tail, then the medicine incense is used for auxiliary treatment on the basis of conventional washing and application of the medicine, a disk of the medicine incense is ignited every afternoon, the lower abdominal pain is relieved after the treatment of burning out the medicine incense for one day is finished, the leucorrhea is recovered to be normal, the external pruritus is disappeared, and the pain in waist and tail is disappeared after the medicine incense is continuously used for 7 days.

Test example 2

The anti-breaking force test is carried out on the medicine incense for conditioning gynecological diseases processed by the invention, and the test result is shown in table 1.

Table 1: table of bending strength test results

	Breaking resistance/N
		Example 1	2.6
Example 2	2.8
		Example 3	2.9
Example 4	3.2
		Example 5	3.3
Example 6	3.6
		Example 7	3.4
Example 8	4.1
		Example 9	4.3
Example 10	3.9
		Comparative example 1	2.7

The medicinal incense for conditioning gynecopathy has good anti-bending performance, is not easy to damage, and is convenient to transport and store. Compared with the example 1, the ionic liquid modification treatment is carried out on the poplar powder serving as the aggregate of the medicinal incense in the examples 2-4, the fiber length, the toughness and the surface roughness of the poplar powder are changed after the ionic liquid modification, and the flexural strength of the medicinal incense prepared by the ionic liquid modification is improved. Examples 5-7 further surface-modified poplar wood flour modified with ionic liquid, using oleamide, vinyltrimethoxysilane, and isopropyl tris (dioctylphosphato acyloxy) titanate as modifiers, respectively, to functionalize the surface of poplar wood flour after modification treatment, and improve the bonding force with the binder. In the examples 8 to 10, a novel sunflower seed meal adhesive is used for preparing the drug fragrance, the sunflower seed adhesive contains a large amount of protein, the molecular chain of the protein is fully extended by performing surface modification on the protein, and then the protein is crosslinked by using a crosslinking agent to obtain a high-viscosity adhesive, so that the anti-folding capability of the drug fragrance obtained by processing the sunflower seed adhesive as a binder is further improved.

Test example 3

The burning time of the incense for conditioning gynecological diseases processed by the invention is tested. The test results are shown in Table 2.

Table 2: burning time test result table

	Burning time/h
		Example 1	7.6
Example 4	8.3
		Example 6	9.0
Example 8	9.4
		Example 9	9.5
Example 10	9.2
		Comparative example 1	7.9

The medicine fragrance of the invention has long burning time and long duration of the medicine effect. It was found that examples 8-10, using sunflower seed adhesive as binder, had improved flavor structure and prolonged burning time compared to examples 1-6.

The foregoing detailed description of the preferred embodiments of the invention has been presented. It should be understood that numerous modifications and variations could be devised by those skilled in the art in light of the present teachings without departing from the inventive concepts. Therefore, the technical solutions available to those skilled in the art through logic analysis, reasoning and limited experiments based on the prior art according to the concept of the present invention should be within the scope of protection defined by the claims.

Claims

1. The medicinal incense for conditioning gynecological diseases is characterized by being prepared from the following raw materials in parts by weight:

2.5-5 parts of motherwort, 3-6 parts of salvia miltiorrhiza, 2-4 parts of angelica, 1.5-3 parts of ligusticum wallichii, 2-4 parts of astragalus membranaceus, 0.5-1 part of eclipta alba, 1-3 parts of rhizoma cyperi, 1-3 parts of bighead atractylodes rhizome, 1.5-4.5 parts of radix paeoniae alba, 0.3-1 part of gastrodia elata, 0.2-0.6 part of cinnamon, 1.5-3 parts of poria cocos, 0.5-1.5 parts of sandalwood, 3-9 parts of modified poplar powder, 10-30 parts of water and 2-6 parts of bonding material;

the preparation method of the modified poplar wood powder comprises the following steps: mixing 25-75g poplar powder and 10-40mL ionic liquid, putting into a stirrer, stirring at 40-45 ℃ for 30-50 minutes at the rotation speed of 200-45 r/min, discharging, sealing, placing in a drying box at 70-85 ℃ for 30-60 minutes to obtain a mixture A, adding the mixture A into 120-45 g water, stirring at 30-45 ℃ for 30-60 minutes at the rotation speed of 100-300 r/min, filtering, washing the precipitate obtained by filtering with 30-60g acetone and 45-90g ethanol, drying at 40-55 ℃ for 12-24 hours to obtain a mixture B, adjusting the pH of 15-45g ethanol water solution with the mass fraction of 85-95% to 3-4 by using glacial acetic acid, adding 0.85-1.7g modifier I, uniformly mixing to obtain a mixed solution C, uniformly spraying all the mixed solution C on the surface of the mixture B, putting the mixture B into a stirrer, stirring the mixture B for 50 to 100 minutes at the temperature of between 60 and 75 ℃ and at the rotating speed of between 300 and 500 revolutions per minute, discharging the mixture, and drying the mixture B for 24 to 48 hours at the temperature of between 40 and 60 ℃ to obtain modified poplar powder;

the ionic liquid is (1-butyl-3-methylimidazole) chloride and 1-butylpyridinium chloride in a mass ratio of (1-4): the mixture of (1-4);

the modifier I is vinyl trimethoxy silane.

2. The incense stick for conditioning gynecological diseases according to claim 1, wherein the binder is one or more of sunflower seed meal adhesive, guar gum and carrageenan.

3. The incense stick for conditioning gynecological diseases according to claim 2, wherein the preparation method of the sunflower seed meal adhesive comprises the following steps: uniformly mixing 120-piece sunflower seed meal powder 240 parts, 200-piece sunflower seed meal 400 parts of water, 12-18 parts of modifier II and 8-12 parts of potassium hydroxide, heating to 55-75 ℃, stirring at the temperature of 55-75 ℃ at the rotating speed of 200-piece sunflower seed meal 300 r/min for 3.5-7 hours, naturally cooling to 30-45 ℃, adding 11.5-23 parts of glutaraldehyde, and stirring at the temperature of 30-45 ℃ at the rotating speed of 250-piece sunflower seed meal 400 r/min for 25-45 minutes to obtain the sunflower seed meal adhesive; the modifier II is one or a mixture of polyvinyl alcohol, sodium dodecyl benzene sulfonate and urea.

4. The incense as claimed in claim 3, wherein the modifier II is the mixture of polyvinyl alcohol and sodium dodecyl benzene sulfonate in the weight ratio of (3-5) to (1-2).

5. The incense for conditioning gynecopathy according to claim 1, wherein the incense is prepared by the following method: weighing the raw materials in parts by weight, respectively drying motherwort, salvia miltiorrhiza, angelica, ligusticum wallichii, astragalus mongholicus, eclipta alba, rhizoma cyperi, bighead atractylodes rhizome, radix paeoniae alba, gastrodia elata, cinnamon, poria cocos and sandalwood at 45-65 ℃ for 6-12 hours, crushing and screening by a 50-80-mesh sieve, mixing the crushed raw materials, putting the raw materials into a stirrer, adding modified poplar powder, water and a binding material, stirring for 30-90 minutes at 45-65 ℃ at a rotating speed of 400 revolutions per minute to obtain a mixture, and performing compression molding and drying on the mixture to obtain the finished medicinal incense.

6. The incense for conditioning gynecopathy according to claim 5, wherein the incense is prepared by the following method: weighing the raw materials in parts by weight, respectively drying motherwort, salvia miltiorrhiza, angelica, ligusticum wallichii, astragalus mongholicus, eclipta alba, rhizoma cyperi, bighead atractylodes rhizome, white paeony root, rhizoma gastrodiae, cinnamon, poria cocos and sandalwood at 45-65 ℃ for 6-12 hours, crushing and sieving with a 50-80-mesh sieve, mixing the crushed raw materials, putting the raw materials into a stirrer, adding modified poplar powder, water and a bonding material, stirring at 45-65 ℃ for 30-90 minutes at a rotation speed of 400 revolutions per minute, obtaining a mixture, pressing the mixture into incense with the diameter of 4.0-4.2mm, coiling into disk-shaped incense with the diameter of 12-15cm and the weight of 25-30g, and drying at 45-55 ℃ to obtain the finished medicine incense.

7. The incense stick for conditioning gynecological diseases according to claim 5 or 6, wherein the moisture content of the finished incense stick is 10-12%.