CN107007735A - Medicine perfume (or spice) dirty for aligning and preparation method thereof - Google Patents

Medicine perfume (or spice) dirty for aligning and preparation method thereof Download PDF

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Publication number
CN107007735A
CN107007735A CN201710132229.4A CN201710132229A CN107007735A CN 107007735 A CN107007735 A CN 107007735A CN 201710132229 A CN201710132229 A CN 201710132229A CN 107007735 A CN107007735 A CN 107007735A
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parts
medicine
aligning
dirty
chinese medicine
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CN107007735B (en
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齐国旺
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Shenyang Yao Moxibustion Biological Technology Co Ltd
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Shenyang Yao Moxibustion Biological Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A61K36/835Aquilaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00Disinfection, sterilisation or deodorisation of air
    • A61L9/01Deodorant compositions
    • A61L9/013Deodorant compositions containing animal or plant extracts, or vegetable material

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Abstract

The invention discloses a kind of medicine perfume (or spice) dirty for aligning and preparation method thereof, the fragrant preparation method of the medicine dirty for aligning comprises the following steps:(1) pre-process:(2) wine steeps;(3) material is mixed;(4) it is compressing;(5) low temperature drying.Present invention medicine perfume (or spice) dirty for aligning and preparation method thereof, by the ultramicro grinding and nanosizing of medicinal material, the fibre structure of medicinal material is destroyed, is easy to molding bonded during processing, the medicine factor is distributed when nano level Chinese medicine can accelerate burning simultaneously, reduces the remaining ash content of burning.By the reasonable compatibility of Chinese medicine, medicine is fragrant to absorb the medicine factor in burning by skin, smell, can reach the function of regulation heart.Prepared by the present invention be used for, and that the dirty medicine perfume of aligning has the advantages that is safe, can burn fully, bactericidal property is good, burning time is lasting, while having effects that regulation heart.

Description

Medicine perfume (or spice) dirty for aligning and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine of incense, and in particular to a kind of medicine perfume (or spice) dirty for aligning and preparation method thereof.
Background technology
Heart disease is the general name of heart disease, and heart disease is divided into according to the cause of disease:Congenital heart disease and acquired heart disease. Wherein acquired heart disease refers to that heart is acted on and caused a disease by external or body internal factor after birth, mainly including following Type:It is coronary heart disease caused by coronary sclerosis, rheumatic heart disease, hypertensive heart disease, infective heart disease, interior Secrete heart disease, the heart disease of hemopathic, Nutrition and Metabolism heart disease of characteristic of disease etc..Traditional Chinese medicine thinks that its pathogenic factor is It is many, and have close relationship with the change of whole body.Main aspect is due to worn with age, healthy tendency virtual loss, internal organs work( It can damage, yin and yang qi and blood disorder adds the influence of the factors such as inernal injuries caused by seven emotions, eating and drinking without temperance, cold stimulation, work and rest immoderation, caused Qi depression to blood stasis, hypofunction of YANG QI in chest, the turbid interior life of phlegm makes heart vessel blockage stasis and caused a disease.Wherein, zang-fu differentiation qi and blood functional disturbance, human body is cloudy The secret balance in Pingyang is destroyed, and is the immanent cause of morbidity.Internal cause is the basis of morbidity, and external cause is the condition of morbidity.
Existing thousand history of the perfume of China, stacte can collect the anima in the world, can contribute to one's peace of mind of inner tranquility, and can reconcile mood.Very Many spices are the important medications of the Chinese tradition traditional Chinese medical science.Ancients have understood very early, scent can beauty, dispel pain, dispelling fatigue, row Solve depression etc..Ming Dynasty Li Shizhen (1518-1593 A.D.)《Compendium of Materia Medica》In just record be used as medicine with " line spices ".Perfume has been used perfume (or spice) as medicine Medicine, scented tea.The treatment of perfume is the aromatic odor and healing ability using pure natural medical, via the olfactory organ or skin of people Absorption, acted by nerve and the circulatory system, the body of people, psychology, spiritual three is reached balance and uniformly.It is fragrant Gas, due to easily infiltration, high fluidity and the characteristics of high imbedibility, can be sucked by the skin or mouth and nose of people, thus reach by The effect of absorption of human body.The conventional perfume of in the market day all adds natural flavor, and human body is damaged using meeting for a long time.Therefore, Research and utilization Chinese medicine adjusts the validity of cardiac function, produce a kind of human body have no toxic side effect, the medicine of adjustable heart it is fragrant.
The content of the invention
To achieve the above object, the present invention is adopted the following technical scheme that:
A kind of fragrant preparation method of medicine dirty for aligning, comprises the following steps:
(1) pre-process;
(2) wine steeps;
(3) material is mixed;
(4) it is compressing;
(5) low temperature drying.
Preferably, a kind of fragrant preparation method of medicine dirty for aligning, comprises the following steps:
(1) pre-process:With boulder crusher preliminary crushing it is 10-20 mesh by Chinese medicine;
(2) wine steeps:By soaking in Chinese liquor 1-3 hour of the Chinese medicine of preliminary crushing with 50-60 degree, filtering, low temperature drying is obtained Chinese medicine is steeped to wine;
(3) material is mixed:Wine is steeped into Chinese medicine, adhesive to be added in mixer, is stirred 15 minutes, stirred with 200 revs/min 25-35 DEG C of temperature is mixed, water is added, is stirred 40-60 minutes with 200 revs/min at 25-35 DEG C, obtains mixed material;
(4) it is compressing:Mixed material is added in molding machine, pressure 2-5MPa, dwell time 1-10 second, temperature is 45-60 DEG C, the demoulding obtains the fragrant first product of the medicine dirty for aligning;
(5) low temperature drying:The fragrant first product of the medicine dirty for aligning is sent into baking oven, it is small in 60-80 DEG C of dry 4-6 of temperature When, obtain the fragrant finished product of the medicine dirty for aligning.
Preferably, a kind of fragrant preparation method of medicine dirty for aligning, comprises the following steps:
(1) pre-process:With boulder crusher preliminary crushing it is 10-20 mesh by Chinese medicine;
(2) wine steeps:By soaking in Chinese liquor 1-3 hour of the Chinese medicine of preliminary crushing with 50-60 degree, filtering, low temperature drying is obtained Chinese medicine is steeped to wine;
(3) ultramicro grinding:Wine is steeped into Chinese medicine and decentralized medium in mass ratio 1:(2-4) is well mixed, and is added to ultra micro In pulverizer, crushed 30-40 minutes at 25-35 DEG C, obtain ultramicro grinding Chinese medicine;
(4) nanosizing:Ultramicro grinding Chinese medicine is crushed with nanometer ram machine, in 130MPa, 300rpm working speed Lower crush Chinese medicine is nanoscale, then dry 10-14 hours at 60-80 DEG C, obtains nanoscale traditional Chinese medicine powder;
(5) material is mixed:Nanoscale traditional Chinese medicine powder, adhesive, combustion adjuvant are added in mixer, with 200 revs/min of stirrings 15 minutes, 25-35 DEG C of whipping temp added water, is stirred 40-60 minutes with 200 revs/min at 25-35 DEG C, obtains mixed material;
(6) it is compressing:Mixed material is added in molding machine, pressure 2-5MPa, dwell time 1-10 second, temperature is 45-60 DEG C, the demoulding obtains the fragrant first product of the medicine dirty for aligning;
(7) low temperature drying:The fragrant first product of the medicine dirty for aligning is sent into baking oven, it is small in 60-80 DEG C of dry 4-6 of temperature When, obtain the fragrant finished product of the medicine dirty for aligning.
Preferably, described Chinese medicine includes the Chinese medicine of following weight parts:1-3 parts of ramulus mori, 1-3 parts of cassia twig, root of Dahurain angelica 1-3 Part, 3-5 parts of the Radix Astragali, 3-5 parts of the coptis, 3-5 parts of agalloch eaglewood, 3-5 parts of dalbergia wood, 3-5 parts of santal, 3-5 parts of dipsacus root, 5-8 parts of rhizome of chuanxiong, the red sage root 5-8 parts, 5-8 parts of reticulate millettia, 3-5 parts of radix scrophulariae, tuber of dwarf lilyturf 3-5 part, 5-8 parts of safflower, 5-8 parts of the radix paeoniae rubrathe, windproof 3-5 parts, spina date seed 5-8 Part, 5-8 parts of Poria cocos, 5-8 parts of Longstamen Onion Bulb, 3-5 parts of Radix Angelicae Sinensis, 3-5 parts of corydalis tuber, 1-3 parts of pseudo-ginseng.
Preferably, decentralized medium is sucrose aqueous solution of ester in step (3).
Preferably, adhesive is glutinous rice flour and/or sodium alginate in step (5), it is highly preferred that described adhesive is glutinous rice Powder and sodium alginate mass ratio (1-10):1 mixture.
Preferably, combustion adjuvant is tea seed powder in step (5).
Preferably, the mass ratio of Chinese medicine and white wine described in step (2) is 1:(1-3).
The invention provides a kind of medicine dirty for aligning is fragrant, it is prepared from using the above method.
Present invention medicine perfume (or spice) dirty for aligning and preparation method thereof, by the ultramicro grinding and nanosizing of medicinal material, destroys medicine The fibre structure of material, is easy to molding bonded during processing, at the same nano level Chinese medicine can accelerate burning when the medicine factor dissipate Hair, reduces the remaining ash content of burning.By the reasonable compatibility of Chinese medicine, medicine it is fragrant in burning by skin, smell absorb medicine because Son, can reach the function of regulation heart.The present invention prepare be used for aligning it is dirty medicine perfume have it is safe, can burn and fill Point, the advantages of bactericidal property is good, burning time is lasting, while having effects that to adjust heart.
Embodiment
Bactericidal property detects foundation:《Disinfection technology standard》2.1.3.5 in (2002 editions).
Bactericidal property detection method:Select volume 20m3Unmanned room carries out on-site disinfection test.Disappeared after closed room Air natural bacteria is sampled 5 minutes before malicious, is compareed as sterilization is preceding.3 samples of one embodiment are lighted in experiment indoors every time Carry out disinfection, sterilization is sampled 5 minutes after 2 hours to room air natural bacteria.Sampling plate is placed in into 37 DEG C to cultivate 48 hours, seen Clump count is examined, experiment is repeated 3 times, calculate natural bacteria extinction rate.
The burn test method of the fragrant finished product of the medicine dirty for aligning:The weight about 2.0g fragrant finished product of medicine is weighed, is burnt to complete Entirely, record burning time and collect the right zero gravity of burning.
Ramulus mori, is moraceae plants mulberry (Morns alba L.) Morns alba L. dry twig.
Cassia twig, is canella Chinese cassia tree Cinnamomum cassia Presl dry twig.
The root of Dahurain angelica, is samphire the root of Dahurain angelica Angelica dahurica (Fisch.exHOffm.) Benth.et Hook.f. dry root.
The Radix Astragali, is legume astragalus mongolicus Astragalus membranaceus (Fisch.) Bge.var.mongholicus (Bge.) Hsiao dry root.
The coptis, is ranunculaceae plant coptis Coplis chinensis Franch dry rhizome.
Agalloch eaglewood, Classification system:Aquilariaagallocha (Lour.) Roxb, is dicotyledon medicine Thymelaeceae arbor Plant agalloch eaglewood Aquilari a agallocha (Lour.) Roxb is injured by nature, and (as being struck by lightning, windbreak is damaged by worms Deng) or infected by fungi by the grease secreted out of after artificial destruction during self-regeneration, condensed into Secretion is exactly agalloch eaglewood.
Dalbergia wood, Classification system:Dalbergia odorifera, are legume dalbergia wood wingceltis Dalbergia odorifera The dry duramen of T.Chen trunks and root.
Santal, Classification system:Santalum album linn, are Santalaceae santal platymiscium santal Santalum The heartwood of album L. trunks.
Dipsacus root, is herbaceos perennial teasel Dipsacus asperoides C.Y.Cheng et T.M.Ai Root.
Ligusticum wallichii, is samphire Ligusticum wallichii Ligusticum chuanxiong Hort. dry rhizome.
The red sage root, is labiate red sage root Salvia miltiorrhiza Bunge. drying root and rhizome.
Reticulate millettia, Classification system:MillettiareticuiataBenth, is legume spatholobus suberectus Spatholobus Suberectus Dunn drying rattan.
Radix scrophulariae, Classification system:FigwortRoot, is goatweed radix scrophulariae Scrophularia NingpoensisHemsl. dry root.
The tuber of dwarf lilyturf, is the liliaceous plant tuber of dwarf lilyturf Ophiopogon japonicus (Thunb.) Ker-Gawl. dried root.
Safflower, is that drying for feverfew safflower Carthamus tinctorius L. is spent.
The radix paeoniae rubrathe, is ranunculaceae plant Chinese herbaceous peony Paeonia lactiflora Pall. dry root.
It is windproof, it is umbelliferae Saposhnikovia divaricata Saposhnikovia divaricata (Turcz.) Schischk. drying Root.
Spina date seed, Classification system:Ziziphus jujuba Mill.var.spinosa, are rhamnaceae plant wild jujube Ziziphus jujuba Mill.var.spinosa (Bunge) Hu ex H.F.Chou dry mature seed.
Poria cocos, Classification system:Wolfiporia cocos, are On Polyporaceae Poria cocos Poria cocos (Schw.) Wolf dry sclerotia.
Longstamen Onion Bulb, is liliaceous plant Allium macrostemon Allium macrostemon Bge. dry bulb.
Radix Angelicae Sinensis, is umbelliferae angelica Angelica sinensis (Oliv.) Diels dry root
Corydalis tuber, is papaveraceae plant corydalis Corydalis yanhusno W.T.Wang dry tuber.
Pseudo-ginseng, is panax araliaceae plant Punax notoginseng (Burk.) F.H.Chen drying root and rhizome.
Glutinous rice flour, the water-milling glutinous rice flour provided using Changzhou Jintan south of the River Zhi Fen Co., Ltds, particle diameter 100-120 mesh.
Sucrose ester, the sucrose ester provided using Hangzhou Rui Lin Chemical Co., Ltd.s, model SE11.The preparation of sucrose ester solution Method:A certain amount of sucrose ester is taken, in the water for being added to 40 DEG C, is stirred 20 minutes, produced with 40 revs/min.
Tea seed powder, the natural tea seed powder provided using the colorful chemical products business department in Longgang District of Shenzhen City Pinghu, particle diameter 120 Mesh.
Sodium alginate, No. CAS:31581-02-9, the food-grade sea provided using Shandong Ya Heng bio tech ltd Mosanom.
PEG-400, No. CAS:The pharmaceutical grade PEG- that federal Fine Chemical Co., Ltd provides in 25322-68-3, Guangdong 400。
Ethanol, No. CAS:64-17-5.
Glycerine, No. CAS:56-81-5.
Boulder crusher, the model CSJ-300 produced using Kai Taiji Machinery Manufacturing Co., Ltd.s of Jiangyin City boulder crusher.
Micronizer, the model WFJ-15 produced using Kai Taiji Machinery Manufacturing Co., Ltd.s of Jiangyin City Ultramicro-powder Broken machine.
Nanometer ram machine, the model NCJJ-200/150 produced using Langfang Tongyong Machinery Manufacturing Co., Ltd. nanometer Collider.
Embodiment 1
The medicine perfume material (parts by weight) dirty for aligning:2 parts of ramulus mori, 2 parts of cassia twig, 2 parts of the root of Dahurain angelica, 4 parts of the Radix Astragali, 4 parts of the coptis, It is 4 parts of agalloch eaglewood, 4 parts of dalbergia wood, 4 parts of santal, 4 parts of dipsacus root, 6 parts of rhizome of chuanxiong, 6 parts of the red sage root, 6 parts of reticulate millettia, 4 parts of radix scrophulariae, 4 parts of the tuber of dwarf lilyturf, red Spend 6 parts, 6 parts of the radix paeoniae rubrathe, windproof 4 parts, 6 parts of spina date seed, 6 parts of Poria cocos, 6 parts of Longstamen Onion Bulb, 4 parts of Radix Angelicae Sinensis, 4 parts of corydalis tuber, 2 parts of pseudo-ginseng, bonding 3 parts of agent, 1 part of tea seed powder.
A kind of fragrant preparation method of medicine dirty for aligning, comprises the following steps:
(1) pre-process:It is 10 mesh by Chinese medicine boulder crusher preliminary crushing;
(2) wine steeps:By the Chinese medicine of preliminary crushing with 52 degree of soaking in Chinese liquor 2 hours, the mass ratio of Chinese medicine and white wine For 1:2, with 300 mesh filter-cloth filterings, filter residue is dried 5 hours in temperature 70 C, obtains wine bubble Chinese medicine;
(3) material is mixed:Wine is steeped into Chinese medicine, adhesive, tea seed powder to be added in mixer, with 200 revs/min of stirrings 15 Minute, 30 DEG C of whipping temp adds 25 parts by weight water, is stirred 50 minutes with 200 revs/min at 30 DEG C, obtains mixed material;
(4) it is compressing:Mixed material is added in molding machine, pressure 4MPa, 5 seconds dwell times, temperature is 50 DEG C, The demoulding, obtains the fragrant first product of the medicine dirty for aligning;
(5) low temperature drying:By in the fragrant first product feeding baking oven of the medicine dirty for aligning, dry 5 hours, obtain in temperature 70 C The fragrant finished product of the medicine dirty for aligning, medicine perfume length is 24 centimetres, a diameter of 3 millimeters.
Adhesive described in step (4) is glutinous rice flour.
Embodiment 2
The medicine perfume material (parts by weight) dirty for aligning:2 parts of ramulus mori, 2 parts of cassia twig, 2 parts of the root of Dahurain angelica, 4 parts of the Radix Astragali, 4 parts of the coptis, It is 4 parts of agalloch eaglewood, 4 parts of dalbergia wood, 4 parts of santal, 4 parts of dipsacus root, 6 parts of rhizome of chuanxiong, 6 parts of the red sage root, 6 parts of reticulate millettia, 4 parts of radix scrophulariae, 4 parts of the tuber of dwarf lilyturf, red Spend 6 parts, 6 parts of the radix paeoniae rubrathe, windproof 4 parts, 6 parts of spina date seed, 6 parts of Poria cocos, 6 parts of Longstamen Onion Bulb, 4 parts of Radix Angelicae Sinensis, 4 parts of corydalis tuber, 2 parts of pseudo-ginseng, bonding 3 parts of agent, 1 part of tea seed powder.
A kind of fragrant preparation method of medicine dirty for aligning, comprises the following steps:
(1) pre-process:It is 10 mesh by Chinese medicine boulder crusher preliminary crushing;
(2) wine steeps:By the Chinese medicine of preliminary crushing with 52 degree of soaking in Chinese liquor 2 hours, the mass ratio of Chinese medicine and white wine For 1:2, with 300 mesh filter-cloth filterings, filter residue is dried 5 hours in temperature 70 C, obtains wine bubble Chinese medicine;
(3) ultramicro grinding:Wine is steeped into Chinese medicine and decentralized medium in mass ratio 1:3 are well mixed, and are added to ultramicro grinding In machine, crush 30 minutes, then dried 12 hours in 70 DEG C of environment at 30 DEG C, obtain ultramicro grinding Chinese medicine;
(4) material is mixed:Ultramicro grinding Chinese medicine, adhesive, tea seed powder are added in mixer, stirred with 200 revs/min Mix 15 minutes, 30 DEG C of whipping temp adds 25 parts by weight water, stirred 50 minutes with 200 revs/min at 30 DEG C, obtain mixed material;
(5) it is compressing:Mixed material is added in molding machine, pressure 4MPa, 5 seconds dwell times, temperature is 50 DEG C, The demoulding, obtains the fragrant first product of the medicine dirty for aligning;
(6) low temperature drying:By in the fragrant first product feeding baking oven of the medicine dirty for aligning, dry 5 hours, obtain in temperature 70 C The fragrant finished product of the medicine dirty for aligning, medicine perfume length is 24 centimetres, a diameter of 3 millimeters.
Decentralized medium described in step (3) is water.
Adhesive described in step (4) is glutinous rice flour.
Embodiment 3
The medicine perfume material (parts by weight) dirty for aligning:2 parts of ramulus mori, 2 parts of cassia twig, 2 parts of the root of Dahurain angelica, 4 parts of the Radix Astragali, 4 parts of the coptis, It is 4 parts of agalloch eaglewood, 4 parts of dalbergia wood, 4 parts of santal, 4 parts of dipsacus root, 6 parts of rhizome of chuanxiong, 6 parts of the red sage root, 6 parts of reticulate millettia, 4 parts of radix scrophulariae, 4 parts of the tuber of dwarf lilyturf, red Spend 6 parts, 6 parts of the radix paeoniae rubrathe, windproof 4 parts, 6 parts of spina date seed, 6 parts of Poria cocos, 6 parts of Longstamen Onion Bulb, 4 parts of Radix Angelicae Sinensis, 4 parts of corydalis tuber, 2 parts of pseudo-ginseng, bonding 3 parts of agent, 1 part of tea seed powder.
A kind of fragrant preparation method of medicine dirty for aligning, comprises the following steps:
(1) pre-process:It is 10 mesh by Chinese medicine boulder crusher preliminary crushing;
(2) wine steeps:By the Chinese medicine of preliminary crushing with 52 degree of soaking in Chinese liquor 2 hours, the mass ratio of Chinese medicine and white wine For 1:2, with 300 mesh filter-cloth filterings, filter residue is dried 5 hours in temperature 70 C, obtains wine bubble Chinese medicine;
(3) ultramicro grinding:Wine is steeped into Chinese medicine and decentralized medium in mass ratio 1:3 are well mixed, and are added to ultramicro grinding In machine, crushed 30 minutes at 30 DEG C, obtain ultramicro grinding Chinese medicine;
(4) nanosizing:Ultramicro grinding Chinese medicine is crushed with nanometer ram machine, in 130MPa, 300rpm working speed Lower crush Chinese medicine is nanoscale, then is dried 12 hours at 70 DEG C, obtains nanoscale traditional Chinese medicine powder;
(5) material is mixed:Nanoscale traditional Chinese medicine powder, adhesive, tea seed powder are added in mixer, with 200 revs/min of stirrings 15 minutes, 30 DEG C of whipping temp added 25 parts by weight water, is stirred 50 minutes with 200 revs/min at 30 DEG C, obtains mixed material;
(6) it is compressing:Mixed material is added in molding machine, pressure 4MPa, 5 seconds dwell times, temperature is 50 DEG C, The demoulding, obtains the fragrant first product of the medicine dirty for aligning;
(7) low temperature drying:By in the fragrant first product feeding baking oven of the medicine dirty for aligning, dry 5 hours, obtain in temperature 70 C The fragrant finished product of the medicine dirty for aligning, medicine perfume length is 24 centimetres, a diameter of 3 millimeters.
Decentralized medium described in step (3) is water.
Adhesive described in step (5) is glutinous rice flour.
Embodiment 4
It is substantially the same manner as Example 3, differ only in:
Decentralized medium described in step (3) is the sucrose aqueous solution of ester that mass fraction is 1%.
Embodiment 5
It is substantially the same manner as Example 3, differ only in:
Decentralized medium described in step (3) is absolute ethyl alcohol.
Embodiment 6
It is substantially the same manner as Example 3, differ only in:
Decentralized medium described in step (3) is glycerine.
Embodiment 7
It is substantially the same manner as Example 3, differ only in:
Described decentralized medium described in step (3) is PEG-400.
Embodiment 8
It is substantially the same manner as Example 4, differ only in:
Decentralized medium described in step (3) is the sucrose aqueous solution of ester that mass fraction is 0.5%.
Embodiment 9
It is substantially the same manner as Example 4, differ only in:
Decentralized medium described in step (3) is the sucrose aqueous solution of ester that mass fraction is 1.5%.
Embodiment 10
It is substantially the same manner as Example 4, differ only in:
Adhesive described in step (5) is sodium alginate.Bactericidal property test result:Natural bacteria extinction rate is within 1 hour 79%;Combustibility test result:Burning time 57min/24cm, combustion residue weight 52mg/24cm.
Embodiment 11
It is substantially the same manner as Example 4, differ only in:
Adhesive described in step (5) is glutinous rice flour and sodium alginate in mass ratio 5:1 mixes.Bactericidal property is tested As a result:1 hour natural bacteria extinction rate is 91%, combustibility test result:Burning time 72min/24cm, combustion residue weight 30mg/24cm。
Test case 1
The fragrant bactericidal property of the dirty medicine of aligning that is used for obtained to embodiment 1-9 detects that concrete outcome is shown in Table 1.
Table 1:Bactericidal property test result table
Embodiment 3 has used ultramicro grinding and nanocrystallization technology, and its bactericidal effect is better than embodiment 1 and embodiment 2, and this is Because Chinese medicine is through ultramicro grinding and nanocrystallization technology, medicinal powder is set to reach in Nano grade, combustion process, the medicine factor is fully released Put, reach good bactericidal effect.
Embodiment 4 uses the use quality fraction during ultramicro grinding to be situated between for 1% sucrose aqueous solution of ester as scattered Matter, its combustion efficiency is better than embodiment 3, embodiment 5-7, and decentralized medium is usually water, ethanol, glycerine, PEG- in the prior art 400 etc., the present invention in inventor be surprised to find that to achieve preferable effect using sucrose aqueous solution of ester because sucrose ester Chinese medicine powder is fully dispersed during the good dispersive property of the aqueous solution makes ultramicro grinding, powder is uniform in size, makes nanometer Journey traditional Chinese medicine powder reaches Nano grade, and medicine chemoattractant molecule can be fully discharged in combustion.
The fragrant combustion efficiency of medicine is better than embodiment 8 and embodiment 9 when the sucrose ester concentration of aqueous solution of embodiment 4 is 1%.
Test case 2
The fragrant combustibility of the dirty medicine of aligning that is used for obtained to embodiment 1-9 detects that concrete outcome is shown in Table 2.
Table 2 is used for the fragrant combustion test of the dirty medicine of aligning
Embodiment 3 has used ultramicro grinding and nanocrystallization technology, and its combustion efficiency is better than embodiment 1 and embodiment 2, and this is Because Chinese medicine is through ultramicro grinding and nanocrystallization technology, medicinal powder is set to be well mixed, medicine perfume internal voids are small, make burning time long And burning is abundant.
Embodiment 4 uses the use quality fraction during ultramicro grinding to be situated between for 1% sucrose aqueous solution of ester as scattered Matter, its combustion efficiency is better than embodiment 3, embodiment 5-7, because the good dispersive property of sucrose aqueous solution of ester makes Ultramicro-powder Chinese medicine powder is uniform during broken, can also make material fully dispersed in material mixed process, and then it is fragrant internal to reduce medicine Space.
The fragrant combustion efficiency of medicine is better than embodiment 8 and embodiment 9 when the sucrose ester concentration of aqueous solution of embodiment 4 is 1%.
Test case 3
The fragrant therapeutic effect of the dirty medicine of aligning that is used for obtained to embodiment 1-11 is detected.
Method of testing:The cardiac 220 at age 20-60 Sui is selected, 11 groups, every group 20, difference are randomly divided into It is used for the dirty medicine perfume of aligning using prepared by embodiment 1-11,5 is used daily, medicine moxibustion is carried out for patient.After 60 days Therapeutic effect data are shown in Table 3.
Patient symptom:Pulse condition knot is for person, the vexed pain person in anterior pectorial region, and palpitaition is moved, and has hospital's color ultrasound and doppler diagnostic.
Treatment standard:
(1) it is effective:Symptom eliminates, appetite increase, muscle power increase is lived as normal person.
(2) effectively:Symptom is partially removed, and appetite increased, and muscle power is slightly recovered.
(3) it is invalid:Symptom is without obvious change
Table 3:Conditions of patients tables of data

Claims (9)

1. the fragrant preparation method of a kind of medicine dirty for aligning, it is characterised in that comprise the following steps:
(1) pre-process;
(2) wine steeps;
(3) material is mixed;
(4) it is compressing;
(5) low temperature drying.
2. the fragrant preparation method of a kind of medicine dirty for aligning, it is characterised in that comprise the following steps:
(1) pre-process:With boulder crusher preliminary crushing it is 10-20 mesh by Chinese medicine;
(2) wine steeps:By soaking in Chinese liquor 1-3 hour of the Chinese medicine of preliminary crushing with 50-60 degree, filtering, low temperature drying obtains wine Steep Chinese medicine;
(3) material is mixed:Wine is steeped into Chinese medicine, adhesive to be added in mixer, stirred 15 minutes with 200 revs/min, stirring temperature 25-35 DEG C of degree, adds water, is stirred 40-60 minutes with 200 revs/min at 25-35 DEG C, obtains mixed material;
(4) it is compressing:Mixed material is added in molding machine, pressure 2-5MPa, dwell time 1-10 second, temperature is 45- 60 DEG C, the demoulding obtains the fragrant first product of the medicine dirty for aligning;
(5) low temperature drying:The fragrant first product of the medicine dirty for aligning is sent into baking oven, it is dry 4-6 hours in 60-80 DEG C of temperature, obtain To the fragrant finished product of the medicine dirty for aligning.
3. the fragrant preparation method of a kind of medicine dirty for aligning, it is characterised in that comprise the following steps:
(1) pre-process:With boulder crusher preliminary crushing it is 10-20 mesh by Chinese medicine;
(2) wine steeps:By soaking in Chinese liquor 1-3 hour of the Chinese medicine of preliminary crushing with 50-60 degree, filtering, low temperature drying obtains wine Steep Chinese medicine;
(3) ultramicro grinding:Wine is steeped into Chinese medicine and decentralized medium in mass ratio 1:(2-4) is well mixed, and is added to ultramicro grinding In machine, crushed 30-40 minutes at 25-35 DEG C, obtain ultramicro grinding Chinese medicine;
(4) nanosizing:Ultramicro grinding Chinese medicine is crushed with nanometer ram machine, will under 130MPa, 300rpm working speed It is nanoscale that Chinese medicine, which is crushed, then dry 10-14 hours at 60-80 DEG C, obtains nanoscale traditional Chinese medicine powder;
(5) material is mixed:Nanoscale traditional Chinese medicine powder, adhesive, combustion adjuvant are added in mixer, 15 points are stirred with 200 revs/min Clock, 25-35 DEG C of whipping temp, adds water, is stirred 40-60 minutes with 200 revs/min at 25-35 DEG C, obtains mixed material;
(6) it is compressing:Mixed material is added in molding machine, pressure 2-5MPa, dwell time 1-10 second, temperature is 45- 60 DEG C, the demoulding obtains the fragrant first product of the medicine dirty for aligning;
(7) low temperature drying:The fragrant first product of the medicine dirty for aligning is sent into baking oven, it is dry 4-6 hours in 60-80 DEG C of temperature, obtain To the fragrant finished product of the medicine dirty for aligning.
4. it is used for the fragrant preparation method of the dirty medicine of aligning as claimed in claim 3, it is characterised in that described Chinese medicine includes The Chinese medicine of following weight parts:1-3 parts of ramulus mori, 1-3 parts of cassia twig, 1-3 parts of the root of Dahurain angelica, 3-5 parts of the Radix Astragali, 3-5 parts of the coptis, 3-5 parts of agalloch eaglewood, 3-5 parts of dalbergia wood, 3-5 parts of santal, 3-5 parts of dipsacus root, 5-8 parts of rhizome of chuanxiong, 5-8 parts of the red sage root, 5-8 parts of reticulate millettia, 3-5 parts of radix scrophulariae, the tuber of dwarf lilyturf 3-5 parts, 5-8 parts of safflower, 5-8 parts of the radix paeoniae rubrathe, windproof 3-5 parts, 5-8 parts of spina date seed, 5-8 parts of Poria cocos, 5-8 parts of Longstamen Onion Bulb, Radix Angelicae Sinensis 3-5 Part, 3-5 parts of corydalis tuber, 1-3 parts of pseudo-ginseng.
5. it is used for the fragrant preparation method of the dirty medicine of aligning as described in claim 3 or 4, it is characterised in that described in step (3) Decentralized medium is sucrose aqueous solution of ester.
6. it is used for the fragrant preparation method of the dirty medicine of aligning as described in claim 3 or 4, it is characterised in that described in step (5) Adhesive is glutinous rice flour and/or sodium alginate.
7. it is used for the fragrant preparation method of the dirty medicine of aligning as described in claim 3 or 4, it is characterised in that described in step (5) Combustion adjuvant is tea seed powder.
8. it is used for the fragrant preparation method of the dirty medicine of aligning as described in claim 3 or 4, it is characterised in that described in step (2) The mass ratio of Chinese medicine and white wine is 1:(1-3).
9. a kind of medicine dirty for aligning is fragrant, it is characterised in that be prepared from using any one of claim 1-8 method.
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CN107412451A (en) * 2017-08-21 2017-12-01 通化康越堂健康科技有限公司 Ginseng agalloch eaglewood and preparation method thereof
CN107970377A (en) * 2018-01-22 2018-05-01 尹淑珍 Nourishing heart shield heart medicine perfume and its production technology
CN108096473A (en) * 2017-12-20 2018-06-01 阮小军 Nurse one's health the medicine perfume and its processing technology of gynaecological disease
CN109395136A (en) * 2018-08-31 2019-03-01 阿坝州慈愿民族传统文化有限责任公司 A kind of dalbergia wood type joss stick produced in Xizang and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN107412451A (en) * 2017-08-21 2017-12-01 通化康越堂健康科技有限公司 Ginseng agalloch eaglewood and preparation method thereof
CN108096473A (en) * 2017-12-20 2018-06-01 阮小军 Nurse one's health the medicine perfume and its processing technology of gynaecological disease
CN108096473B (en) * 2017-12-20 2021-02-23 嘉兴市舒福特生物科技有限公司 Medicinal incense for conditioning gynecopathy and processing technology thereof
CN107970377A (en) * 2018-01-22 2018-05-01 尹淑珍 Nourishing heart shield heart medicine perfume and its production technology
CN109395136A (en) * 2018-08-31 2019-03-01 阿坝州慈愿民族传统文化有限责任公司 A kind of dalbergia wood type joss stick produced in Xizang and preparation method thereof

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