WO2017220052A2 - Formulation treating rheumatoid bone pain - Google Patents

Formulation treating rheumatoid bone pain Download PDF

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Publication number
WO2017220052A2
WO2017220052A2 PCT/CN2017/097792 CN2017097792W WO2017220052A2 WO 2017220052 A2 WO2017220052 A2 WO 2017220052A2 CN 2017097792 W CN2017097792 W CN 2017097792W WO 2017220052 A2 WO2017220052 A2 WO 2017220052A2
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grams
bone
follows
plantain
measured
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PCT/CN2017/097792
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French (fr)
Chinese (zh)
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WO2017220052A3 (en
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崔坤峰
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赵吉永
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/34—Campanulaceae (Bellflower family)
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486—Millettia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/68—Plantaginaceae (Plantain Family)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Definitions

  • the invention relates to a formula for treating rheumatism, in particular to a formula for treating rheumatism and bone pain, belonging to the technical field of traditional Chinese medicine formula.
  • the main cause of rheumatism is that the human body is affected by wind, humidity and cold, affecting the metabolism and circulation of blood and gas in certain parts, causing lesions.
  • the incidence is serious; often have a lot to do with occupations and living habits, rain, wading, long-term damp place to suffer cold, cold, heat, heat Long-term work in the environment; there are rheumatism caused by trauma, more common in falls, joint sprains, external damage and other reasons, leading to blood stasis, congestion and congestion, resulting in muscle, tendon, joint swelling, pain
  • patients generally have a common feature: the body is weak; when the body is weak due to qi and blood, it is easy to get rheumatism.
  • Cisoka topical Chinese medicine for treating bone hyperplasia and rheumatism consists of A component and B component, which is made of the following raw materials of weight ratio: 10-30 of blood, 10-30 of Tianqi, 20-40 of bone broken, 10 ⁇ 30, safflower 20 ⁇ 40, ephedra 20 ⁇ 40, frankincense 10 ⁇ 30, angelica 10 ⁇ 30, myrrh 10 ⁇ 30, continued 10 ⁇ 30, soil aphid 10 ⁇ 30; the B component is as follows Made of weight-matched raw materials: white with an alcohol content of 30 to 35 degrees 5 ⁇ 15, 10 ⁇ 30 vinegar; by weight of the component A and component B ratio of 1/5 to 6.
  • the invention Compared with the prior art, the invention has the advantages of simple composition and good therapeutic effect, and is suitable for patients of all ages, and there is no phenomenon of body allergy caused by oral medicinal liquor or topical plaster, and there is no possibility of not drinking or overwhelming.
  • the phenomenon of treatment within the treatment cannot be completed, and the safety is higher; However, it does not follow the gradual process of Chinese medicine; although it can quickly relieve pain, it is prone to recurrence.
  • the present invention provides a formula for treating rheumatism and bone pain, which can be used for pain in a link condition, and at the same time, adopts a method of supplementing and supplementing blood to block blood stasis and congestion; in addition, it can improve immunity and metabolism. To reduce the possibility of recurrence.
  • the invention relates to a rheumatoid bone pain formula, which comprises an internal formula and an external heat treatment component;
  • the components of the oral administration formula are measured in grams as follows: ⁇ 1 ⁇ 10g, scutellaria 1 ⁇ 10g, schisandra 1 ⁇ 10g, Codonopsis 1 ⁇ 10g, sheep bone 5 ⁇ 15g, bovine bone marrow 5 ⁇ 20g, ⁇ 1 ⁇ 15g, clam shell 1 ⁇ 10g, peach kernel 1 ⁇ 15g, ginseng ginseng 1 ⁇ 15g, ginkgo biloba leaf 1 ⁇ 5g, woody incense 1 ⁇ 15g, loofah 5 ⁇ 15g, safflower 1 ⁇ 10g, chicken bone grass 1 ⁇ 15g, spatholobus 1 ⁇ 15g, plantain grass 1 ⁇ 15g; the external thermotherapy component is measured in grams as follows: atractylodes 5 ⁇ 25g, spatholobus 5 ⁇ 15g, ⁇ 1 ⁇ 20g, plantain 5 ⁇ 15g, ginger Tablets 5 ⁇ 10g, dried tangerine peel 5 ⁇ 10g, Bupleurum 5 ⁇ 10g, which use internal
  • the external thermotherapy component performs hyperthermia on the affected part by local hyperthermia or steam therapy, and the hyperthermia can directly deliver the drug to the affected part, and at the same time, can drive out the body's damp cold.
  • the internal formulation component is measured in grams as follows: 3g, Astragalus 3g, Schisandra 1g, Codonopsis pilosula 3g, sheep bone 5g, beef bone marrow 5g, glutinous rice 5g, oyster shell 5g, peach kernel 10g, ginseng 7g 5g, ginkgo biloba leaf 2g, woody 5g, loofah 10g, safflower 10g, 10g of chicken bone grass, 15g of spatholobus suberectus, 15g of plantain;
  • the external thermotherapy component is measured in grams as follows: 25g of Atractylodes, 15g of Spatholobus suberectus, 5g of Strychnos chinensis, 10g of plantain, 10g of ginger, and tangerine peel 5g, Bupleurum 5g; it can reach the affected area directly, treat the pain in the disease, and can treat the pain in time. It is a radical process, and can be supplemented with
  • the oral administration component is measured in grams as follows: ⁇ 3g, astragalus 3g, schisandra 1g, Codonopsis pilosula 3g, sheep bone 5g, bovine bone marrow 5g, sputum white 15g, clam shell 10g, peach kernel 15g, ginseng 15g, ginkgo biloba 5g, woody 10g, loofah 15g, safflower 2g, chicken bone grass 5g, spatholobus 5g, plantain 5g;
  • the external thermotherapy component is measured in grams as follows: Atractylodes 20g, chicken blood Vine 10g, Strychnos 10g, Plantain 5g, Ginger 10g, dried tangerine peel 5g, Bupleurum 10g; it can be supplemented by Tong, mainly to clear the meridians, and at the same time improve the body's immunity, which is generally relieved after body pain Use is a process of remedy.
  • the oral administration component is measured in grams as follows: ⁇ 10g, astragalus 10g, schisandra 10g, Codonopsis pilosula 10g, sheep bone 15g, bovine bone marrow 20g, sputum white 5g, clam shell 5g, peach kernel 10g, ginseng 5g, ginkgo biloba 2g, woody 5g, loofah 10g, safflower 2g, chicken bone grass 5g, spatholobus 5g, plantain 5g; the external thermotherapy component is measured in grams as follows: atractylodes 5 ⁇ 25g, The main purpose of spatholobus 15g, scutellaria 15g, plantain 10g, ginger 10g, tangerine peel 5g, Bupleurum 10g is to improve the body's immunity. It is generally used after the body muscles are dredged. It is generally used for the consolidation of the later stages of treatment.
  • the invention relates to the rheumatoid bone pain formula of the invention, which adopts internal and external local hyperthermia for internal and external administration, thereby improving the good therapeutic effect; and the component of the oral administration formula can cause pain in the link condition; At the same time, it adopts the method of supplementing and supplementing, treating blood stasis and congestion and coagulation; in addition, it can improve immunity and metabolism, and reduce the possibility of recurrence.
  • the invention relates to a rheumatoid bone pain formula, which comprises an internal formula and an external heat treatment component;
  • the components of the oral administration formula are measured in grams as follows: ⁇ 1 ⁇ 10g, scutellaria 1 ⁇ 10g, schisandra 1 ⁇ 10g, Codonopsis 1 ⁇ 10g, sheep bone 5 ⁇ 15g, bovine bone marrow 5 ⁇ 20g, ⁇ 1 ⁇ 15g, clam shell 1 ⁇ 10g, peach kernel 1 ⁇ 15g, ginseng ginseng 1 ⁇ 15g, ginkgo biloba leaf 1 ⁇ 5g, woody incense 1 ⁇ 15g, loofah 5 ⁇ 15g, safflower 1 ⁇ 10g, chicken bone grass 1 ⁇ 15g, spatholobus 1 ⁇ 15g, plantain grass 1 ⁇ 15g; the external thermotherapy component is measured in grams as follows: atractylodes 5 ⁇ 25g, spatholobus 5 ⁇ 15g, ⁇ 1 ⁇ 20g, plantain 5 ⁇ 15g, ginger Tablets 5 ⁇ 10g, dried tangerine peel 5 ⁇ 10g, Bupleurum 5 ⁇ 10g, which use internal
  • the external thermotherapy component performs hyperthermia on the affected part by local hyperthermia or steam therapy, and the hyperthermia can directly deliver the medicine to the affected part, and at the same time, can drive out the body's damp cold.
  • the components of the oral administration formula are measured in grams as follows: ⁇ 3g, astragalus 3g, schisandra 1g, Codonopsis pilosula 3g, sheep bone 5g, bovine bone marrow 5g, cockroach white 5g, oyster shell 5g, peach kernel 10g, ginseng ginseng 5g, ginkgo biloba leaf 2g, Woody 5g, loofah 10g, safflower 10g, chicken bone grass 10g, spatholobus 15g, plantain 15g; the external thermotherapy component is measured in grams as follows: Atractylodes 25g, spatholobus 15g, scorpion 5g, plantain 10g, ginger 10g, dried tangerine peel 5g, Bupleurum 5g; it can reach the affected area directly, treat the pain in the link, and can treat the pain in time, which is a process of curing the disease, and can be supplemented by Improve the body's immunity, which is mainly for the treatment of
  • the components of the oral administration formula are measured in grams as follows: ⁇ 3g, astragalus 3g, schisandra 1g, Codonopsis pilosula 3g, sheep bone 5g, bovine bone marrow 5g, white peony 15g, clam shell 10g, peach kernel 15g, ginseng ginseng 15g, ginkgo biloba leaf 5g, Woody 10g, loofah 15g, safflower 2g, chicken bone grass 5g, spatholobus 5g, plantain 5g; the external thermotherapy component is measured in grams as follows: Atractylodes 20g, spatholobus 10g, scorpion 10g, plantain 5g, ginger 10g, dried tangerine peel 5g, Bupleurum 10g; it can be supplemented by Tong, mainly to clear the meridians, and at the same time improve the body's immunity, which is generally used after the body pain is relieved, is a cure process.
  • the components of the oral administration formula are measured in grams as follows: ⁇ 10g, astragalus 10g, schisandra 10g, codonopsis 10g, sheep bone 15g, bovine bone marrow 20g, sputum white 5g, clam shell 5g, peach kernel 10g, ginseng saponin 5g, ginkgo biloba leaf 2g, Woody 5g, loofah 10g, safflower 2g, chicken bone grass 5g, spatholobus 5g, plantain 5g; the external thermotherapy component is measured in grams as follows: atractylodes 5 ⁇ 25g, spatholobus 15g, horse Money 15g, plantain 10g, ginger 10g, dried tangerine peel 5g, Bupleurum 10g Its main purpose is to improve the body's immunity, which is generally used after the body muscles are dredged. It is a radical process, which is generally used for the consolidation of the later stage of treatment.
  • the invention relates to the rheumatoid bone pain formula of the invention, which adopts internal and external local hyperthermia for internal and external administration, thereby improving the good therapeutic effect; and the component of the oral administration formula can cause pain in the link condition; At the same time, it adopts the method of supplementing and supplementing, treating blood stasis and congestion and coagulation; in addition, it can improve immunity and metabolism, and reduce the possibility of recurrence.

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  • Developmental Biology & Embryology (AREA)
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Abstract

Disclosed is a formulation treating rheumatoid bone pain, said formulation comprising oral formulation and external heat treatment components. The oral formulation components are as follows, by gram: 1-10 grams of poria, 1-10 grams of radix astragali, 1-10 grams of fructus schisandrae, 1-10 grams of radix codonopsis, 5-15 grams of sheep bone, 5-20 grams of ox marrow, 1-15 grams of bulbus allii macrostemi, 1-10 grams of fructus aurantii, 1-15 grams of semen persicae, 1-15 grams of panax notoginseng, 1-5 grams of folium ginkgo, 1-15 grams of radix aucklandiae, 5-15 grams of retinervus luffae fructus, 1-10 grams of flos carthami, 1-15 grams of herba abri, 1-15 grams of caulis spatholobi, and 1-15 grams of herba plantaginis. The external heat treatment components are as follows, by gram: 5-25 grams of rhizoma atractylodis, 5-15 grams of caulis spatholobi, 1-20 grams of semen strychni, 5-15 grams of herba plantaginis, 5-10 grams of ginger, 5-10 grams of pericarpium citri reticulatae, and 5-10 grams of radix bupleuri. The formulation treating rheumatoid bone pain uses oral and external local heat treatment means for internal and external administration, improving a treatment effect. The oral formulation components ease pain at the affected area. The formulation uses supplementation means to treat qi and blood stagnation and blood stasis and coagulation, improves immunity and metabolism, and reduces the possibility of relapse.

Description

一种治疗风湿骨痛配方Formula for treating rheumatism and bone pain 技术领域Technical field
本发明涉及一种治疗风湿病配方，具体涉及一种治疗风湿骨痛配方，属于中药配方技术领域。The invention relates to a formula for treating rheumatism, in particular to a formula for treating rheumatism and bone pain, belonging to the technical field of traditional Chinese medicine formula.
背景技术Background technique
风湿产生的主要原因是人体受到风、湿、寒的侵袭，影响某些部位的血、气等代谢、循环，引起病变。在天气变化异常，如温差较大、下雨、下雪、阴湿状况下，发病严重；往往跟职业和生活习惯有很大关系，冒雨涉水、久居潮湿之地受凉、寒热、暑湿的环境下长期劳作；还有外伤引起的风湿，多见于跌打闪挫，关节扭伤，外力损伤等原因，导致气血阻滞、淤血凝聚，从而出现肌肉、筋脉、关节局部的肿胀、疼痛，麻木不仁；风湿病患者普遍有一个共同特点：身体虚弱；当身体内因气血衰弱，就容易得风湿骨病，中国专利申请号201310308113.3，公开了一种治疗骨质增生、风湿骨痛的外用中药，它由A组分和B组分组成，所述A组分由下述重量配比的原料制成：血竭10～30、田七10～30、骨碎补20～40、全蝎10～30、红花20～40、麻黄20～40、乳香10～30、当归10～30、没药10～30、续断10～30、土鳖虫10～30；所述B组分由下述重量配比的原料制成：酒精度为30～35度的白酒5～15、米醋10～30；所述B组分和A组分的重量比为1∶5～6。与现有技术相比，本发明组方简单、治疗效果好，适合各个年龄段的患者，不存在因口服药酒或外用贴膏导致身体过敏的现象，也不存在因不会饮酒或不胜酒力而无法完成疗程内的治疗的现象，安全性更高； 但其并没有根据中医循序渐进的过程；虽然能够快速止痛，但其容易复发。The main cause of rheumatism is that the human body is affected by wind, humidity and cold, affecting the metabolism and circulation of blood and gas in certain parts, causing lesions. In the abnormal weather changes, such as large temperature difference, rain, snow, wet conditions, the incidence is serious; often have a lot to do with occupations and living habits, rain, wading, long-term damp place to suffer cold, cold, heat, heat Long-term work in the environment; there are rheumatism caused by trauma, more common in falls, joint sprains, external damage and other reasons, leading to blood stasis, congestion and congestion, resulting in muscle, tendon, joint swelling, pain Rheumatism patients generally have a common feature: the body is weak; when the body is weak due to qi and blood, it is easy to get rheumatism. Chinese Patent Application No. 201310308113.3, discloses a topical Chinese medicine for treating bone hyperplasia and rheumatism. It consists of A component and B component, which is made of the following raw materials of weight ratio: 10-30 of blood, 10-30 of Tianqi, 20-40 of bone broken, 10 ~ 30, safflower 20 ~ 40, ephedra 20 ~ 40, frankincense 10 ~ 30, angelica 10 ~ 30, myrrh 10 ~ 30, continued 10 ~ 30, soil aphid 10 ~ 30; the B component is as follows Made of weight-matched raw materials: white with an alcohol content of 30 to 35 degrees 5 ~ 15, 10 ~ 30 vinegar; by weight of the component A and component B ratio of 1/5 to 6. Compared with the prior art, the invention has the advantages of simple composition and good therapeutic effect, and is suitable for patients of all ages, and there is no phenomenon of body allergy caused by oral medicinal liquor or topical plaster, and there is no possibility of not drinking or overwhelming. The phenomenon of treatment within the treatment cannot be completed, and the safety is higher; However, it does not follow the gradual process of Chinese medicine; although it can quickly relieve pain, it is prone to recurrence.
发明内容Summary of the invention
为解决上述问题，本发明提出了一种治疗风湿骨痛配方，能够环节病症处疼痛；同时采用以通代补的方式，治疗气血阻滞和淤血凝聚；另外其能够提高免疫力和新陈代谢能力，减小复发可能。In order to solve the above problems, the present invention provides a formula for treating rheumatism and bone pain, which can be used for pain in a link condition, and at the same time, adopts a method of supplementing and supplementing blood to block blood stasis and congestion; in addition, it can improve immunity and metabolism. To reduce the possibility of recurrence.
本发明的治疗风湿骨痛配方，所述配方包括内服配方和外部热疗组份；The invention relates to a rheumatoid bone pain formula, which comprises an internal formula and an external heat treatment component;
所述内服配方组份以克计量如下：茯苓1～10g、黄芪1～10g、五味子1～10g，党参1～10g、羊骨5～15g、牛骨髓5～20g、薤白1～15g、枳壳1～10g、桃仁1～15g、参三七1～15g、银杏叶1～5g、木香1～15g、丝瓜络5～15g、红花1～10g、鸡骨草1～15g、鸡血藤1～15g、车前草1～15g；所述外部热疗组份以克计量如下：苍术5～25g、鸡血藤5～15g、马钱子1～20g、车前草5～15g、姜片5～10g、陈皮5～10g、柴胡5～10g，其采用内服和外部局部热疗方式进行内外给药，提高好的治疗效果；其通过内服配方组份能够提高了免疫力和新陈代谢能力，治疗气血阻滞和淤血凝聚；同时能够环节病症处疼痛；同时采用以通代补的方式，提高治疗效果。The components of the oral administration formula are measured in grams as follows: 茯苓1～10g, scutellaria 1～10g, schisandra 1～10g, Codonopsis 1～10g, sheep bone 5～15g, bovine bone marrow 5～20g, 薤白1～15g, clam shell 1～10g, peach kernel 1～15g, ginseng ginseng 1～15g, ginkgo biloba leaf 1～5g, woody incense 1～15g, loofah 5～15g, safflower 1～10g, chicken bone grass 1～15g, spatholobus 1～15g, plantain grass 1～15g; the external thermotherapy component is measured in grams as follows: atractylodes 5～25g, spatholobus 5～15g, 钱钱子1～20g, plantain 5～15g, ginger Tablets 5 ~ 10g, dried tangerine peel 5 ~ 10g, Bupleurum 5 ~ 10g, which use internal and external local hyperthermia for internal and external administration, improve the good therapeutic effect; it can improve immunity and metabolism by oral administration of components To treat qi and blood blockage and congestion of blood stasis; at the same time, it can be painful at the linkage; at the same time, it can improve the treatment effect by means of supplementation.
进一步地，所述外部热疗组份通过局部热疗或蒸气疗法对患处进行热疗，通过热疗既能够将药物直接送至患处，同时能够驱赶出身体的湿冷。Further, the external thermotherapy component performs hyperthermia on the affected part by local hyperthermia or steam therapy, and the hyperthermia can directly deliver the drug to the affected part, and at the same time, can drive out the body's damp cold.
作为优选的实施方案，所述内服配方组份以克计量如下：茯苓 3g、黄芪3g、五味子1g，党参3g、羊骨5g、牛骨髓5g、薤白5g、枳壳5g、桃仁10g、参三七5g、银杏叶2g、木香5g、丝瓜络10g、红花10g、鸡骨草10g、鸡血藤15g、车前草15g；所述外部热疗组份以克计量如下：苍术25g、鸡血藤15g、马钱子5g、车前草10g、姜片10g、陈皮5g、柴胡5g；其能够直达患处，主治环节病症处疼痛，能够及时治疗疼痛，其是一个治本的过程，同时能够辅以以通代补和提高身体免疫力，其主要是针对患者疼痛发作复发时进行治疗。As a preferred embodiment, the internal formulation component is measured in grams as follows: 3g, Astragalus 3g, Schisandra 1g, Codonopsis pilosula 3g, sheep bone 5g, beef bone marrow 5g, glutinous rice 5g, oyster shell 5g, peach kernel 10g, ginseng 7g 5g, ginkgo biloba leaf 2g, woody 5g, loofah 10g, safflower 10g, 10g of chicken bone grass, 15g of spatholobus suberectus, 15g of plantain; the external thermotherapy component is measured in grams as follows: 25g of Atractylodes, 15g of Spatholobus suberectus, 5g of Strychnos chinensis, 10g of plantain, 10g of ginger, and tangerine peel 5g, Bupleurum 5g; it can reach the affected area directly, treat the pain in the disease, and can treat the pain in time. It is a radical process, and can be supplemented with the supplement and improve the body immunity. It is mainly for the patient's pain. Treatment is performed at the time of recurrence.
作为优选的实施方案，所述内服配方组份以克计量如下：茯苓3g、黄芪3g、五味子1g，党参3g、羊骨5g、牛骨髓5g、薤白15g、枳壳10g、桃仁15g、参三七15g、银杏叶5g、木香10g、丝瓜络15g、红花2g、鸡骨草5g、鸡血藤5g、车前草5g；所述外部热疗组份以克计量如下：苍术20g、鸡血藤10g、马钱子10g、车前草5g、姜片10g、陈皮5g、柴胡10g；其能够以通代补，主要是疏通经络，同时能够提高身体免疫力，其一般在身体疼痛缓解后使用，是一个治本的过程。As a preferred embodiment, the oral administration component is measured in grams as follows: 茯苓3g, astragalus 3g, schisandra 1g, Codonopsis pilosula 3g, sheep bone 5g, bovine bone marrow 5g, sputum white 15g, clam shell 10g, peach kernel 15g, ginseng 15g, ginkgo biloba 5g, woody 10g, loofah 15g, safflower 2g, chicken bone grass 5g, spatholobus 5g, plantain 5g; the external thermotherapy component is measured in grams as follows: Atractylodes 20g, chicken blood Vine 10g, Strychnos 10g, Plantain 5g, Ginger 10g, dried tangerine peel 5g, Bupleurum 10g; it can be supplemented by Tong, mainly to clear the meridians, and at the same time improve the body's immunity, which is generally relieved after body pain Use is a process of remedy.
作为优选的实施方案，所述内服配方组份以克计量如下：茯苓10g、黄芪10g、五味子10g，党参10g、羊骨15g、牛骨髓20g、薤白5g、枳壳5g、桃仁10g、参三七5g、银杏叶2g、木香5g、丝瓜络10g、红花2g、鸡骨草5g、鸡血藤5g、车前草5g；所述外部热疗组份以克计量如下：苍术5～25g、鸡血藤15g、马钱子15g、车前草10g、姜片10g、陈皮5g、柴胡10g其主要目的是提高身体免疫力，其一般在身体筋络疏通后使用，是一个治本的过程，其一般用于治疗后期的巩固。 As a preferred embodiment, the oral administration component is measured in grams as follows: 茯苓10g, astragalus 10g, schisandra 10g, Codonopsis pilosula 10g, sheep bone 15g, bovine bone marrow 20g, sputum white 5g, clam shell 5g, peach kernel 10g, ginseng 5g, ginkgo biloba 2g, woody 5g, loofah 10g, safflower 2g, chicken bone grass 5g, spatholobus 5g, plantain 5g; the external thermotherapy component is measured in grams as follows: atractylodes 5 ~ 25g, The main purpose of spatholobus 15g, scutellaria 15g, plantain 10g, ginger 10g, tangerine peel 5g, Bupleurum 10g is to improve the body's immunity. It is generally used after the body muscles are dredged. It is generally used for the consolidation of the later stages of treatment.
本发明与现有技术相比较，本发明的治疗风湿骨痛配方，其采用内服和外部局部热疗方式进行内外给药，提高好的治疗效果；其通过内服配方组份能够环节病症处疼痛；同时采用以通代补的方式，治疗气血阻滞和淤血凝聚；另外其能够提高免疫力和新陈代谢能力，减小复发可能。Compared with the prior art, the invention relates to the rheumatoid bone pain formula of the invention, which adopts internal and external local hyperthermia for internal and external administration, thereby improving the good therapeutic effect; and the component of the oral administration formula can cause pain in the link condition; At the same time, it adopts the method of supplementing and supplementing, treating blood stasis and congestion and coagulation; in addition, it can improve immunity and metabolism, and reduce the possibility of recurrence.
具体实施方式detailed description
本发明的治疗风湿骨痛配方，所述配方包括内服配方和外部热疗组份；The invention relates to a rheumatoid bone pain formula, which comprises an internal formula and an external heat treatment component;
所述内服配方组份以克计量如下：茯苓1～10g、黄芪1～10g、五味子1～10g，党参1～10g、羊骨5～15g、牛骨髓5～20g、薤白1～15g、枳壳1～10g、桃仁1～15g、参三七1～15g、银杏叶1～5g、木香1～15g、丝瓜络5～15g、红花1～10g、鸡骨草1～15g、鸡血藤1～15g、车前草1～15g；所述外部热疗组份以克计量如下：苍术5～25g、鸡血藤5～15g、马钱子1～20g、车前草5～15g、姜片5～10g、陈皮5～10g、柴胡5～10g，其采用内服和外部局部热疗方式进行内外给药，提高好的治疗效果；其通过内服配方组份能够提高了免疫力和新陈代谢能力，治疗气血阻滞和淤血凝聚；同时能够环节病症处疼痛；同时采用以通代补的方式，提高治疗效果。The components of the oral administration formula are measured in grams as follows: 茯苓1～10g, scutellaria 1～10g, schisandra 1～10g, Codonopsis 1～10g, sheep bone 5～15g, bovine bone marrow 5～20g, 薤白1～15g, clam shell 1～10g, peach kernel 1～15g, ginseng ginseng 1～15g, ginkgo biloba leaf 1～5g, woody incense 1～15g, loofah 5～15g, safflower 1～10g, chicken bone grass 1～15g, spatholobus 1～15g, plantain grass 1～15g; the external thermotherapy component is measured in grams as follows: atractylodes 5～25g, spatholobus 5～15g, 钱钱子1～20g, plantain 5～15g, ginger Tablets 5 ~ 10g, dried tangerine peel 5 ~ 10g, Bupleurum 5 ~ 10g, which use internal and external local hyperthermia for internal and external administration, improve the good therapeutic effect; it can improve immunity and metabolism by oral administration of components To treat qi and blood blockage and congestion of blood stasis; at the same time, it can be painful at the linkage; at the same time, it can improve the treatment effect by means of supplementation.
其中，所述外部热疗组份通过局部热疗或蒸气疗法对患处进行热疗，通过热疗既能够将药物直接送至患处，同时能够驱赶出身体的湿冷。Wherein, the external thermotherapy component performs hyperthermia on the affected part by local hyperthermia or steam therapy, and the hyperthermia can directly deliver the medicine to the affected part, and at the same time, can drive out the body's damp cold.
实施例1： Example 1:
所述内服配方组份以克计量如下：茯苓3g、黄芪3g、五味子1g，党参3g、羊骨5g、牛骨髓5g、薤白5g、枳壳5g、桃仁10g、参三七5g、银杏叶2g、木香5g、丝瓜络10g、红花10g、鸡骨草10g、鸡血藤15g、车前草15g；所述外部热疗组份以克计量如下：苍术25g、鸡血藤15g、马钱子5g、车前草10g、姜片10g、陈皮5g、柴胡5g；其能够直达患处，主治环节病症处疼痛，能够及时治疗疼痛，其是一个治本的过程，同时能够辅以以通代补和提高身体免疫力，其主要是针对患者疼痛发作复发时进行治疗。The components of the oral administration formula are measured in grams as follows: 茯苓3g, astragalus 3g, schisandra 1g, Codonopsis pilosula 3g, sheep bone 5g, bovine bone marrow 5g, cockroach white 5g, oyster shell 5g, peach kernel 10g, ginseng ginseng 5g, ginkgo biloba leaf 2g, Woody 5g, loofah 10g, safflower 10g, chicken bone grass 10g, spatholobus 15g, plantain 15g; the external thermotherapy component is measured in grams as follows: Atractylodes 25g, spatholobus 15g, scorpion 5g, plantain 10g, ginger 10g, dried tangerine peel 5g, Bupleurum 5g; it can reach the affected area directly, treat the pain in the link, and can treat the pain in time, which is a process of curing the disease, and can be supplemented by Improve the body's immunity, which is mainly for the treatment of patients with pain recurrence.
实施例2：Example 2:
所述内服配方组份以克计量如下：茯苓3g、黄芪3g、五味子1g，党参3g、羊骨5g、牛骨髓5g、薤白15g、枳壳10g、桃仁15g、参三七15g、银杏叶5g、木香10g、丝瓜络15g、红花2g、鸡骨草5g、鸡血藤5g、车前草5g；所述外部热疗组份以克计量如下：苍术20g、鸡血藤10g、马钱子10g、车前草5g、姜片10g、陈皮5g、柴胡10g；其能够以通代补，主要是疏通经络，同时能够提高身体免疫力，其一般在身体疼痛缓解后使用，是一个治本的过程。The components of the oral administration formula are measured in grams as follows: 茯苓3g, astragalus 3g, schisandra 1g, Codonopsis pilosula 3g, sheep bone 5g, bovine bone marrow 5g, white peony 15g, clam shell 10g, peach kernel 15g, ginseng ginseng 15g, ginkgo biloba leaf 5g, Woody 10g, loofah 15g, safflower 2g, chicken bone grass 5g, spatholobus 5g, plantain 5g; the external thermotherapy component is measured in grams as follows: Atractylodes 20g, spatholobus 10g, scorpion 10g, plantain 5g, ginger 10g, dried tangerine peel 5g, Bupleurum 10g; it can be supplemented by Tong, mainly to clear the meridians, and at the same time improve the body's immunity, which is generally used after the body pain is relieved, is a cure process.
实施例3：Example 3:
所述内服配方组份以克计量如下：茯苓10g、黄芪10g、五味子10g，党参10g、羊骨15g、牛骨髓20g、薤白5g、枳壳5g、桃仁10g、参三七5g、银杏叶2g、木香5g、丝瓜络10g、红花2g、鸡骨草5g、鸡血藤5g、车前草5g；所述外部热疗组份以克计量如下：苍术5～25g、鸡血藤15g、马钱子15g、车前草10g、姜片10g、陈皮5g、柴胡10g 其主要目的是提高身体免疫力，其一般在身体筋络疏通后使用，是一个治本的过程，其一般用于治疗后期的巩固。The components of the oral administration formula are measured in grams as follows: 茯苓10g, astragalus 10g, schisandra 10g, codonopsis 10g, sheep bone 15g, bovine bone marrow 20g, sputum white 5g, clam shell 5g, peach kernel 10g, ginseng saponin 5g, ginkgo biloba leaf 2g, Woody 5g, loofah 10g, safflower 2g, chicken bone grass 5g, spatholobus 5g, plantain 5g; the external thermotherapy component is measured in grams as follows: atractylodes 5 ~ 25g, spatholobus 15g, horse Money 15g, plantain 10g, ginger 10g, dried tangerine peel 5g, Bupleurum 10g Its main purpose is to improve the body's immunity, which is generally used after the body muscles are dredged. It is a radical process, which is generally used for the consolidation of the later stage of treatment.
本发明与现有技术相比较，本发明的治疗风湿骨痛配方，其采用内服和外部局部热疗方式进行内外给药，提高好的治疗效果；其通过内服配方组份能够环节病症处疼痛；同时采用以通代补的方式，治疗气血阻滞和淤血凝聚；另外其能够提高免疫力和新陈代谢能力，减小复发可能。Compared with the prior art, the invention relates to the rheumatoid bone pain formula of the invention, which adopts internal and external local hyperthermia for internal and external administration, thereby improving the good therapeutic effect; and the component of the oral administration formula can cause pain in the link condition; At the same time, it adopts the method of supplementing and supplementing, treating blood stasis and congestion and coagulation; in addition, it can improve immunity and metabolism, and reduce the possibility of recurrence.
以上述依据本发明的理想实施例为启示，通过上述的说明内容，相关工作人员完全可以在不偏离本项发明技术思想的范围内，进行多样的变更以及修改。本项发明的技术性范围并不局限于说明书上的内容，必须要根据权利要求范围来确定其技术性范围。 In view of the above-described embodiments of the present invention, various changes and modifications may be made by those skilled in the art without departing from the scope of the invention. The technical scope of the present invention is not limited to the contents of the specification, and the technical scope thereof must be determined according to the scope of the claims.

Claims (5)

  1. 一种治疗风湿骨痛配方，其特征在于：所述配方包括内服配方和外部热疗组份；A formula for treating rheumatic bone pain, characterized in that the formula comprises an internal formula and an external heat treatment component;
    所述内服配方组份以克计量如下：茯苓1～10g、黄芪1～10g、五味子1～10g，党参1～10g、羊骨5～15g、牛骨髓5～20g、薤白1～15g、枳壳1～10g、桃仁1～15g、参三七1～15g、银杏叶1～5g、木香1～15g、丝瓜络5～15g、红花1～10g、鸡骨草1～15g、鸡血藤1～15g、车前草1～15g；The components of the oral administration formula are measured in grams as follows: 茯苓1～10g, scutellaria 1～10g, schisandra 1～10g, Codonopsis 1～10g, sheep bone 5～15g, bovine bone marrow 5～20g, 薤白1～15g, clam shell 1～10g, peach kernel 1～15g, ginseng ginseng 1～15g, ginkgo biloba leaf 1～5g, woody incense 1～15g, loofah 5～15g, safflower 1～10g, chicken bone grass 1～15g, spatholobus 1 ~ 15g, plantain grass 1 ~ 15g;
    所述外部热疗组份以克计量如下：苍术5～25g、鸡血藤5～15g、马钱子1～20g、车前草5～15g、姜片5～10g、陈皮5～10g、柴胡5～10g。The external thermotherapy component is measured in grams as follows: 5~25g of Atractylodes, 5-15g of Spatholobus suberectus, 1-20g of Strychnos chinensis, 5-15g of plantain, 5-10g of ginger, 5-10g of dried tangerine peel, firewood Hu 5 ~ 10g.
  2. 根据权利要求1所述的治疗风湿骨痛配方，其特征在于：所述外部热疗组份通过局部热疗或蒸气疗法对患处进行热疗。The rheumatoid bone pain formula according to claim 1, wherein the external thermotherapy component is subjected to hyperthermia of the affected part by local hyperthermia or steam therapy.
  3. 根据权利要求1所述的治疗风湿骨痛配方，其特征在于：所述内服配方组份以克计量如下：茯苓3g、黄芪3g、五味子1g，党参3g、羊骨5g、牛骨髓5g、薤白5g、枳壳5g、桃仁10g、参三七5g、银杏叶2g、木香5g、丝瓜络10g、红花10g、鸡骨草10g、鸡血藤15g、车前草15g；所述外部热疗组份以克计量如下：苍术25g、鸡血藤15g、马钱子5g、车前草10g、姜片10g、陈皮5g、柴胡5g。The rheumatoid bone pain formula according to claim 1, wherein the oral administration component is measured in grams as follows: 茯苓3g, scutellaria 3g, schisandra 1g, codonopsis pilose 3g, sheep bone 5g, bovine bone marrow 5g, sputum white 5g , clam shell 5g, peach kernel 10g, ginseng saponin 5g, ginkgo biloba 2g, woody 5g, loofah 10g, safflower 10g, chicken bone grass 10g, spatholobus 15g, plantain 15g; the external thermotherapy group The weight is measured as follows: 25g of Atractylodes, 15g of Spatholobus suberectus, 5g of Strychnos chinensis, 10g of plantain, 10g of ginger, 5g of dried tangerine peel, 5g of Bupleurum.
  4. 根据权利要求1所述的治疗风湿骨痛配方，其特征在于：所述内服配方组份以克计量如下：茯苓3g、黄芪3g、五味子1g，党参3g、羊骨5g、牛骨髓5g、薤白15g、枳壳10g、桃仁15g、参三七15g、银杏叶5g、木香10g、丝瓜络15g、红花2g、鸡骨草5g、鸡血藤5g、车前草5g；所述外部热疗组份以克计量如下：苍术20g、鸡血藤10g、 马钱子10g、车前草5g、姜片10g、陈皮5g、柴胡10g。The rheumatoid bone pain formula according to claim 1, wherein the oral administration component is measured in grams as follows: 茯苓3g, scutellaria 3g, schisandra 1g, Codonopsis pilosula 3g, sheep bone 5g, bovine bone marrow 5g, sputum white 15g , clam shell 10g, peach kernel 15g, ginseng ginseng 15g, ginkgo biloba leaf 5g, woody incense 10g, loofah 15g, safflower 2g, chicken bone grass 5g, spatholobus 5g, plantain 5g; the external thermotherapy group The weight is measured as follows: Atractylodes 20g, Spatholobus suberectus 10g, 10kg of horse money, 5g of plantain, 10g of ginger, 5g of dried tangerine peel, 10g of Bupleurum.
  5. 根据权利要求1所述的治疗风湿骨痛配方，其特征在于：所述内服配方组份以克计量如下：茯苓10g、黄芪10g、五味子10g，党参10g、羊骨15g、牛骨髓20g、薤白5g、枳壳5g、桃仁10g、参三七5g、银杏叶2g、木香5g、丝瓜络10g、红花2g、鸡骨草5g、鸡血藤5g、车前草5g；所述外部热疗组份以克计量如下：苍术5～25g、鸡血藤15g、马钱子15g、车前草10g、姜片10g、陈皮5g、柴胡10g。 The rheumatoid bone pain formula according to claim 1, wherein the oral administration component is measured in grams as follows: 茯苓10g, scutellaria 10g, schisandra 10g, Codonopsis pilosula 10g, sheep bone 15g, bovine bone marrow 20g, sputum white 5g , clam shell 5g, peach kernel 10g, ginseng 7g 5g, ginkgo biloba 2g, woody 5g, loofah 10g, safflower 2g, chicken bone grass 5g, spatholobus 5g, plantain 5g; the external thermotherapy group The weight is measured as follows: 5~25g of Atractylodes Rhizome, 15g of Spatholobus suberectus, 15g of Strychnos chinensis, 10g of plantain, 10g of ginger, 5g of dried tangerine peel, 10g of Bupleurum.
PCT/CN2017/097792 2016-06-21 2017-08-17 Formulation treating rheumatoid bone pain WO2017220052A2 (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108114261A (en) * 2018-02-08 2018-06-05 刘秀华 A kind of unique old plaster of the tingle swelling pain noresidue of effectively treatment rheumatism bone disease
CN109464636A (en) * 2018-10-19 2019-03-15 锦州紫金药业有限公司 A kind of dispelling cold and removing dampness of improvement, quack medicine of promoting blood circulation and stopping pain and its preparation method and application

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* Cited by examiner, † Cited by third party
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CN106075009A (en) * 2016-06-21 2016-11-09 崔坤峰 One treats rheumatic ostalgia formula

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CN102988909A (en) * 2011-09-15 2013-03-27 刘瑞林 Rheumatoid bone rubbing wine
CN106075009A (en) * 2016-06-21 2016-11-09 崔坤峰 One treats rheumatic ostalgia formula

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108114261A (en) * 2018-02-08 2018-06-05 刘秀华 A kind of unique old plaster of the tingle swelling pain noresidue of effectively treatment rheumatism bone disease
CN109464636A (en) * 2018-10-19 2019-03-15 锦州紫金药业有限公司 A kind of dispelling cold and removing dampness of improvement, quack medicine of promoting blood circulation and stopping pain and its preparation method and application

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