WO2017220046A2

WO2017220046A2 - Formulation treating rheumatoid osteomyelitis

Info

Publication number: WO2017220046A2
Application number: PCT/CN2017/097781
Authority: WO
Inventors: 崔坤峰
Original assignee: 赵吉永
Priority date: 2016-06-21
Filing date: 2017-08-17
Publication date: 2017-12-28
Also published as: WO2017220046A3; CN105963515A

Abstract

Disclosed is a formulation treating rheumatoid osteomyelitis, said formulation comprising an oral formulation and an external application formulation. The oral formulation has the following components by gram: 5-10 grams of poria, 5-10 grams of peeled ramulus cinnamomi, 5-10 grams of rhizoma atractylodis macrocephalae, 5-10 grams of roasted radix glycyrrhizae, 5-10 grams of caulis spatholobi, 5-10 grams of radix astragali, 5-10 grams of rhizoma atractylodis macrocephalae, 5-10 grams of radix glycyrrhizae, 5-10 grams of radix rehmanniae preparata, 15-20 grams of fructus corni, 5-10 grams of cortex moutan, 5-10 grams of rhizoma polygonati, 10-15 grams of walnut, 10-15 grams of rehmannia glutinosa, 15-20 grams of semen sesami nigrum, 15-20 grams of ox bone, and 10-15 grams of rhizoma cibotii. The external application formulation has the following components by gram: 10-20 grams of allium tuberosum root and leaf, 5-10 grams of eupolyphaga sinensis, 10-20 grams of herba menthae, 10-20 grams of caulis spatholobi, 10-20 grams of radix paeoniae rubra, 5-10 grams of earthworm, 10-15 grams of flos carthami, 10-15 grams of radix angelicae sinensis, 10-15 grams of radix aucklandiae, 10-20 grams of herba speranskiae tuberculatae, 10-20 grams of fructus chaenomelis, 10-20 grams of dipsacus asperoides, 10-20 grams of gendarussa ventricosa, 10-20 grams of herba gendarussae, and 10-20 grams of christia vespertilionis. The formulation is passed through a hundred mesh sieve and mixed with honey into a paste for use. The formulation treating rheumatoid osteomyelitis has few side effects, treats the cause of the disease, can be applied to the affected area, and reduces pain at the affected area.

Description

Formula for treating rheumatic osteomyelitis

Technical field

The invention relates to an osteomyelitis formula, in particular to a formula for treating rheumatoid osteomyelitis, belonging to the technical field of traditional Chinese medicine formula.

Background technique

Rheumatoid osteomyelitis is a chronic rheumatic immune disease caused by disorders of the immune system. Common external causes include fatigue, cold, mood and environment, etc., which can cause disease; immune complexes due to disorders of the immune system Deposition, deposition in the joints will cause synovitis of the joints and joint pain and swelling, deposition in the organs will cause damage to the organs and related symptoms, the disease can not be completely cured, there is a tendency to recurrent; China Patent application number: 01123757.0, discloses an osteomyelitis plaster, which is characterized in that its raw material formula is: all Angelica 20g, Zhengchuanxi 15g, Dashengdi 20g, Hangbaiyu 15g, Guangmuxiang 20g, 20 grams of myrrh, 20 grams of Chuanhonghua, 20 grams of Sichuan peach, 20 grams of frankincense, 15 grams of whole glutinous rice, 15 mites, 15 grams of eucalyptus, 20 grams of honeysuckle, 20 grams of white stalk, 20 grams of white peony, forsythia 20 grams, 20 grams of rhubarb, 20 grams of Chuanwu, 20 grams of Shangangui, 20 grams of fragrant white peony, 20 grams of black ginseng, 15 grams of blood charcoal, 15 grams of spotted peony, 20 grams of Sichuan achyranthes, 20 grams of Kawada , Guangdan 1 kg, made into a plaster; the invention Osteomyelitis to be treated, a tumor, it is a significant effect, no side effects; the above formulation to treat osteomyelitis common, but difficult to treat rheumatic for osteomyelitis.

Summary of the invention

In order to solve the above problems, the present invention proposes a rheumatoid osteomyelitis formula which can be treated in the early and middle stages according to specific needs, and the treatment is based on internal and external application. Stereoscopic administration can not only treat the cause, but also can be used for the patient to reduce the pain in the affected area.

The therapeutic rheumatoid osteomyelitis formulation of the present invention, the formulation component comprising an internal formulation and an external formulation;

The components of the oral administration formula are measured in grams as follows: 茯苓5～10g, peeled cassia twig 5～10g, Atractylodes cinerea 5～10g, licorice 炙5～10g, spatholobus sinensis 5～10g, scutellaria 5～10g, Atractylodes 5 ～10g, licorice 5～10g, rehmannia glutinosa 5～10g, hawthorn 15～20g, peony bark 5～10g, huangjing 5～10g, walnut 10～15g, raw land 10～15g, black sesame 15～20g, beef bone 15～ 20g and dog ridge 10 ~ 15g;

The external application formula is measured in grams as follows: 10-20 g of alfalfa roots, 5-10 g of soil aphids, 10-20 g of mint grass, 10-20 g of spatholobus suberectus, 10-20 g of red peony, 5-10 g of earthworms, 10 to 15g of safflower, 10 to 15g of angelica, 10 to 15g of woody, 10 to 20g of sclerotium, 10 to 20g of papaya, 10 to 20g of continuous stalk, 10 to 20g of large rib, 10 to 20g of small rib and Shuangfei butterfly 10-20g; the above formula is passed through a 100 mesh sieve and then mixed into a paste by honey. When used, the paste preparation prepared by the above is coated with gauze on the affected part.

As a preferred embodiment, the oral administration component is measured in grams as follows: 茯苓5g, peeled cassia twig 5g, Atractylodes macrocephala 5g, licorice root 5g, spatholobus suberectus 5g, astragalus 10g, Atractylodes macrocephala 10g, licorice 10g, rehmannia glutinosa 10g, hawthorn 20g, peony bark 10g, huangjing 10g, walnut 15g, raw land 15g, black sesame 20g, beef bone 20g and dog ridge 15g; Chinese medicine believes that the kidney is the main bone, the Tibetan essence, so the rheumatoid osteomyelitis is generally liver Kidney has a certain loss, so through the above-mentioned components, oral administration can complete the treatment of liver and kidney, and at the same time can help treat blood stasis and phlegm, warm and cold; it can cure rheumatic osteomyelitis and early treatment; The external application formula is measured in grams as follows: g root 韭 leaf 20g, soil mites 5g, mint grass 20g, spatholobus 10g, red peony root 10g, earthworm 5g, safflower 15g, angelica 15g, woody 15g, stalk 20g, papaya 20g, Chuan continued 20g, large rib bone 10g, small rib bone 10g and Shuangfei butterfly 20g; through the above-mentioned component formula external application can complete the disease to remove heat and phlegm and pain, which can be used for rheumatic osteomyelitis Direct drug effect, can quickly reduce the pain of the disease.

As a preferred embodiment, the oral administration component is measured in grams as follows: 茯苓10g, peeled cassia twig 10g, Atractylodes 10g, licorice root 10g, spatholobus 10g, scutellaria 5g, Atractylodes 5g, licorice 5g, Rehmannia glutinosa 5g, hawthorn 15g, peony bark 5g, huangjing 5g, walnut 10g, raw land 10g, black sesame 15g, beef bone 15g and dog ridge 15g; therefore, through the above-mentioned components, oral administration can complete the treatment of blood stasis, warming cold and wet, and at the same time Auxiliary treatment of liver and kidney; it can gradually treat rheumatoid osteomyelitis, which is mainly for mid-term or post-treatment, and can be used for rehabilitation and consolidation; the external application formula is measured in grams as follows: 20g of alfalfa roots, 10g of soil aphid , 10g of mint grass, 20g of spatholobus suberectus, 20g of red peony root, 10g of radix rehmanniae, 10g of safflower, 10g of angelica, 10g of woody incense, 10g of scented stalk, 20g of stalk, 10g of papaya, 10g of stalk, 20g of large bone, small bone 20g and Shuangfei Butterfly 10g; external application of the above-mentioned component formula can complete the external treatment of mydriatic analgesia and pathogenic bone marrow, which can gradually treat and link pain in rheumatic osteomyelitis.

As a preferred embodiment, the oral administration component is measured in grams as follows: 茯苓7g, peeled cassia twig 7g, Atractylodes sinensis 7g, licorice root 7g, spatholobus 10g, astragalus 7g, Atractylodes 7g, licorice 7g, rehmannia glutinosa 10g, hawthorn 20g, peony bark 5g, huangjing 5g, walnut 10g, raw land 10g, black sesame 15g, beef bone 20g and dog ridge 15g; therefore, the above formula can be used to gradually complete blood stasis, warming cold and replenishing liver Kidney It is sufficient for the progressive treatment of rheumatoid osteomyelitis, which can be treated and consolidated for a long time; the external application formula is measured in grams as follows: 20g of medlar root, 7g of soil mites, 10g of peppermint, 15g of spatholobus, 15g of red peony , Dilong 5g, safflower 10g, Angelica 10g, woody 10g, sclerotium 10g, papaya 10g, Chuan continued 15g, large ribs 15g, small ribs 15g and Shuangfei butterfly 15g; therefore external application through the above components It can complete the external treatment of mydriasis and pain and the source of bone marrow, which can gradually treat and link pain in rheumatic osteomyelitis, without side effects.

Compared with the prior art, the invention has the advantages of small side effects in the treatment of rheumatoid osteomyelitis, and can be treated in the early and middle stages according to specific needs, and the treatment is carried out by internal and external application for all-dimensional administration, which can be used for the cause. The treatment can also be used to treat the patient and reduce the pain in the affected area.

detailed description

The external application formula is measured in grams as follows: 10-20 g of alfalfa roots, 5-10 g of soil aphids, 10-20 g of mint grass, 10-20 g of spatholobus suberectus, 10-20 g of red peony, 5-10 g of earthworms, 10 to 15g of safflower, 10 to 15g of angelica, 10 to 15g of woody, 10 to 20g of stalk, 10 to 20g of papaya, 10~20g in Sichuan, 10~20g in large ribs, 10~20g in small ribs and 10~20g in double flying butterflies; the above formula is mixed with honey and mixed into a paste by 100 mesh sieve. When used, the above system is used. The resulting paste formulation is covered with gauze on the affected area.

Example 1:

The components of the oral administration formula are measured in grams as follows: 茯苓5g, peeled cassia twig 5g, Atractylodes macrocephala 5g, licorice root 5g, spatholobus suberectus 5g, astragalus 10g, Atractylodes macrocephala 10g, licorice 10g, rehmannia root 10g, hawthorn 20g, peony 10g, 10g of Huangjing, 15g of walnut, 15g of raw land, 20g of black sesame, 20g of beef bone and 15g of dog ridge; Chinese medicine believes that the kidney is the main bone, and the essence of the marrow is preserved. Therefore, rheumatoid osteomyelitis usually has a certain loss in liver and kidney. Through the above-mentioned components, oral administration can complete the treatment of liver and kidney, and can also assist in the treatment of blood stasis and phlegm, warming cold and dampness; it can cure rheumatoid osteomyelitis and early treatment; the external application formula is measured in grams as follows: Loquat leaves 20g, soil mites 5g, mint grass 20g, spatholobus 10g, red peony root 10g, earthworm 5g, safflower 15g, angelica 15g, woody 15g, turfgrass 20g, papaya 20g, chuanchuan 20g, large The rib bone 10g, the small rib bone 10g and the Shuangfei butterfly 20g; the external application of the above component formula can complete the heat and disperse pain of the disease, which can directly achieve the effect on the rheumatoid osteomyelitis condition, and can quickly alleviate the pain of the disease.

Example 2:

The components of the oral administration formula are measured in grams as follows: 茯苓10g, peeled cassia twig 10g, Atractylodes macrocephala 10g, licorice root 10g, spatholobus suberectus 10g, astragalus 5g, Atractylodes rhizome 5g, licorice 5g, rehmannia root 5g, hawthorn 15g, peony 5g, 5g of Huangjing, 10g of walnut, 10g of raw land, 15g of black sesame, 15g of beef bone, 15g of dog bone and 15g of dog ridge; therefore, it can complete the treatment of blood stasis, warming cold and dampness, and can assist in the treatment of liver and kidney; It can Rheumatoid osteomyelitis progressive treatment, which is mainly for mid-term or post-treatment, and can be used for rehabilitation and consolidation; the external application formula is measured in grams as follows: 韭 root 20 leaf 20g, soil mites 10g, mint grass 10g, spatholobus 20g , red peony 20g, earthworm 10g, safflower 10g, angelica 10g, woody 10g, stalk grass 20g, papaya 10g, Sichuan sulcus 10g, large rib bone 20g, small rib bone 20g and double flying butterfly 10g; through the above group The topical application can complete the external treatment of mydriasis and pain and the source of bone marrow, which can provide stepwise treatment and pain in the rheumatic osteomyelitis.

Example 3:

The components of the oral administration formula are measured in grams as follows: 茯苓7g, peeled cassia twig 7g, Atractylodes macrocephala 7g, licorice root 7g, spatholobus suberectus 10g, astragalus 7g, Atractylodes 7g, licorice 7g, rehmannia root 10g, hawthorn 20g, peony 5g, 5g, 5g, 10g, 10g of black sesame, 15g of black sesame, 20g of beef bone and 15g of dog ridge; therefore, it can gradually complete blood stasis, warming cold and moistening liver and kidney by oral administration of the above components; it can be used for rheumatism Sexual osteomyelitis progressive treatment, which can be treated and consolidated for a long time; the external application formula is measured in grams as follows: 韭 root 20 leaves 20g, soil mites 7g, mint grass 10g, spatholobus 15g, red peony 15g, earth dragon 5g, safflower 10g, angelica 10g, woody 10g, sclerotium 10g, papaya 10g, Chuan continued 15g, large ribs 15g, small ribs 15g and double flying butterfly 15g; therefore, the external application of the above components can complete the dispersion瘀 Analgesic and pathological external bone marrow treatment, which can provide step-by-step treatment and pain in rheumatic osteomyelitis, without side effects.

The therapeutic rheumatoid osteomyelitis formula of the invention has the advantages of small side effects, and can be treated in the early and middle stages according to specific needs, and the treatment is performed by internal and external application of all-dimensional stereoscopic administration, which can treat the cause and can be targeted to the patient. Use medicine to reduce pain in the affected area pain.

In view of the above-described embodiments of the present invention, various changes and modifications may be made by those skilled in the art without departing from the scope of the invention. The technical scope of the present invention is not limited to the contents of the specification, and the technical scope thereof must be determined according to the scope of the claims.

Claims

The invention relates to a rheumatoid osteomyelitis formula, characterized in that the formula component comprises an internal formula and an external application formula;

The components of the oral administration formula are measured in grams as follows: 茯苓5～10g, peeled cassia twig 5～10g, Atractylodes cinerea 5～10g, licorice 炙5～10g, spatholobus sinensis 5～10g, scutellaria 5～10g, Atractylodes 5 ～10g, licorice 5～10g, rehmannia glutinosa 5～10g, hawthorn 15～20g, peony bark 5～10g, huangjing 5～10g, walnut 10～15g, raw land 10～15g, black sesame 15～20g, beef bone 15～ 20g and dog ridge 10 ~ 15g;

The external application formula is measured in grams as follows: 10-20 g of alfalfa roots, 5-10 g of soil aphids, 10-20 g of mint grass, 10-20 g of spatholobus suberectus, 10-20 g of red peony, 5-10 g of earthworms, 10 to 15g of safflower, 10 to 15g of angelica, 10 to 15g of woody, 10 to 20g of sclerotium, 10 to 20g of papaya, 10 to 20g of continuous stalk, 10 to 20g of large rib, 10 to 20g of small rib and Shuangfei butterfly 10 ~ 20g; the above formula is passed through a 100 mesh sieve and then mixed into a paste by honey.
The rheumatoid osteomyelitis preparation according to claim 1, wherein the oral administration component is measured in grams as follows: 茯苓5g, peeled cassia twig 5g, atractylodes 5g, licorice root 5g, spatholobus 5g , Astragalus 10g, Atractylodes 10g, Licorice 10g, Radix Rehmanniae 10g, Hawthorn 20g, Mudanpi 10g, Polygonatum 10g, Walnut 15g, Raw Ground 15g, Black Sesame 20g, Beef Bone 20g and Dog Ridge 15g; The external application formula is in grams The measurement is as follows: 韭 root 韭 leaf 20g, soil mites 5g, mint grass 20g, spatholobus 10g, red peony root 10g, earthworm 5g, safflower 15g, angelica 15g, woody 15g, stalk grass 20g, papaya 20g, Sichuan Continued 20g, 10g of large bones, 10g of small bones and 20g of double flying butterflies.
The rheumatoid osteomyelitis formula according to claim 1, wherein the oral administration component is measured in grams as follows: 茯苓10 g, peeled cassia twig 10 g, atractylodes 10g, licorice root 10g, spatholobus 10g, astragalus 5g, Atractylodes rhizome 5g, licorice 5g, rehmannia root 5g, hawthorn 15g, peony bark 5g, huangjing 5g, walnut 10g, raw land 10g, black sesame 15g, beef bone 15g and dog ridge 15g; the external application formula is measured in grams as follows: 韭 root 20 leaf 20g, soil mites 10g, mint grass 10g, spatholobus stem 20g, red peony root 20g, earthworm 10g, safflower 10g, angelica 10g, woody 10g 20g of sclerotium, 10g of papaya, 10g of continuous stalk, 20g of large ribs, 20g of small ribs and 10g of double flying butterfly.
The rheumatoid osteomyelitis formula according to claim 1, wherein the oral administration component is measured in grams as follows: 茯苓7g, peeled cassia twig 7g, Atractylodes 7g, licorice root 7g, spatholobus 10g , Astragalus 7g, Atractylodes 7g, Licorice 7g, Radix Rehmanniae 10g, Hawthorn 20g, Mudanpi 5g, Polygonatum 5g, Walnut 10g, Raw Ground 10g, Black Sesame 15g, Beef Bone 20g and Dog Ridge 15g; The external application formula is in grams The measurement is as follows: 韭 root 韭 leaf 20g, soil mites 7g, mint grass 10g, spatholobus 15g, red peony 15g, earthworm 5g, safflower 10g, angelica 10g, woody 10g, stalk 10g, papaya 10g, Sichuan Continued 15g, 15g of large bones, 15g of small bones and 15g of double flying butterflies.