CN103381216B - Traditional Chinese medicine composite for curing periarthritis of shoulder and preparation method thereof - Google Patents
Traditional Chinese medicine composite for curing periarthritis of shoulder and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composite for curing periarthritis of shoulder and a preparation method thereof. The traditional Chinese medicine composite comprises following components in parts by weight: 15 to 35 parts of levisticum, 15 to 35 parts of caulis piperis kadsurae, 15 to 35 parts of murraya paniculata, 15 to 35 parts of evodia, 12 to 30 parts of taxillus, 12 to 30 parts of spatholobus stem, 10 to 25 parts of cuttlebone, 10 to 25 parts of celastrus orbiculatus and 5 to 10 parts of natural copper. The traditional Chinese medicine composition can be prepared into a medicine preparation, which can be accepted by any clinic, through traditional Chinese medicine preparation methods. The traditional Chinese medicine composition has the functions of dispelling wind, eliminating dampness, dispelling cold, promoting the circulation of Qi, relaxing tendons, activating collaterals, and promoting blood circulation to arrest pain. Clinic effects have shown that the traditional Chinese medicine composition has a definite and reliable curative effect on periarthritis of shoulder, treats both symptoms and root causes, is safe on clinical application and has no toxic or side effects.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to Chinese medicine composition of a kind of cure scapulohumeral periarthritis and preparation method thereof, belong to the treatment by Chinese herbs field of scapulohumeral periarthritis.
Background technology
Scapulohumeral periarthritis full name is scapulohumeral periarthritis, is the common disease that is cardinal symptom with shoulder arthralgia and inconvenient activity, is commonly called as solidifying shoulder, scapulohumeral periarthritis or congealed shoulder.How because the flesh thorax, synovial bursa etc. of shoulder joint surrounding tissue is by caused by freezing, wound, infection, be the chronic aseptic inflammation of the soft tissues such as shoulder joint Surrounding muscles, tendon, synovial bursa and joint capsule, many patients are caused by rheumatism.Its cardinal symptom is neck shoulder constant pain, and ipsilateral upper limb is raised, rotate, swing is limited, meets wind and meets cold sensation and have heavy dull pain.As treated not in time, delay and with the passing of time can make joint accretion, ipsilateral upper limb attenuates, and unablely even forms disuse atrophy.This disease is more common in the middle age of about 50 years old, and the young and the old also has generation.When showing effect serious, patient pain unbearably, lies awake all night.
Modern Chinese medicine thinks the morbidity of scapulohumeral periarthritis and insufficiency of vital energy and blood, and affection of exogenous wind-cold is wet and sprain and contusion impairment caused by overstrain is relevant, injures shoulder muscle arteries and veins, causes QI and blood obstructed and pain, then bone growth promoting numbness.In traditional Chinese medical science allusion doctor's nationality " Plain Questions numbness opinion ", there are the classification such as rheumatism involving the bone, muscular rheumatism, BI-syndrome involved the blood vessels, BI-syndrome related to skin, think that its cause of disease and wind and cold wet relevant.In " Ling Shu Miraculous Pivot or Divine Axis harmful wind " section, propose its morbidity first in close relations with wound, think that the rear stagnant blood of wound stops gathering between muscle muscles and bones, QI-blood circulation is smooth, and be subject to wind-cold damp pathogen and invade, stagnant blood and exopathogen are attacked and then sent out as arthromyodynia.At Sui-Tang bines, recognize that again its morbidity is relevant with impairment caused by overstrain insufficiency of vital energy and blood further.Record in " celestial being awards treating trauma and fracture secret recipe ": " muscles and bones in spite of wound, shoulder and back ache ".Indicate that itself and wound have definite relation.Summarize for thousands of years to the understanding of shoulder brachialgia to Qing Dynasty's Golden Mirror of Medicine, point out that pain in the shoulder and back has blockage of meridian-QI, the deficiency of vital energy, blood deficiency and double wind, the syndromes such as expectorant of holding concurrently.Claim primary disease " scapulohumeral periarthritis ", " scapulohumeral periarthritis " etc. in Chinese medicine, belong to arthromyodynia category.Many bodies are with age empty, and wind-cold damp pathogen is taken advantage of a weak point, and causes and hinders through BI-syndrome involved the blood vessels; Or tumbling down damage, in blood stasis stays, QI and blood is not all right, and muscles along the regular meridians effect is not normal and road causes primary disease.
At present, the Chinese patent medicine being used for the treatment of scapulohumeral periarthritis also existing all is in various degree taken effect slow, the defect such as curative effect is remarkable not, haves much room for improvement.
Summary of the invention
Technical problem to be solved by this invention be overcome existing cure scapulohumeral periarthritis existing take effect slow, curative effect not significantly, the defect such as toxic and side effects is large, the Chinese medicine composition of cure scapulohumeral periarthritis provide a kind of instant effect, determined curative effect, having no side effect;
Another technical problem to be solved by this invention is to provide a kind of method preparing above-mentioned Chinese medicine composition.
Above-mentioned technical problem to be solved by this invention is achieved through the following technical solutions:
A Chinese medicine composition for cure scapulohumeral periarthritis, comprises each component composition of following weight portion: Radix Angelicae Pubescentis, Caulis Piperis Kadsurae, Folium Et Cacumen Murrayae, Fructus Evodiae, Herba Taxilli, Caulis Spatholobi, Carnis Rapanae thomasianae Octopus ocellatus Gray, Celastrus orbiculatus Thunb., Pyritum.
Preferably, the weight portion of each component is: Radix Angelicae Pubescentis 15-35 part, Caulis Piperis Kadsurae 15-35 part, Folium Et Cacumen Murrayae 15-35 part, Fructus Evodiae 15-35 part, Herba Taxilli 12-30 part, Caulis Spatholobi 12-30 part, Carnis Rapanae thomasianae Octopus ocellatus Gray 10-25 part, Celastrus orbiculatus Thunb. 10-25 part, Pyritum 5-10 part.
More select, the weight portion of each component is: Radix Angelicae Pubescentis 15-25 part, Caulis Piperis Kadsurae 15-25 part, Folium Et Cacumen Murrayae 15-25 part, Fructus Evodiae 15-25 part, Herba Taxilli 12-20 part, Caulis Spatholobi 12-20 part, Carnis Rapanae thomasianae Octopus ocellatus Gray 10-15 part, Celastrus orbiculatus Thunb. 10-15 part, Pyritum 5-8 part.
Most preferred, the weight portion of each component is: Radix Angelicae Pubescentis 20 parts, Caulis Piperis Kadsurae 20 parts, Folium Et Cacumen Murrayae 20 parts, Fructus Evodiae 20 parts, Herba Taxilli 16 parts, Caulis Spatholobi 16 parts, Carnis Rapanae thomasianae Octopus ocellatus Gray 12 parts, Celastrus orbiculatus Thunb. 12 parts, Pyritum 7 parts.
Radix Angelicae Pubescentis: different name solely shakes grass, solely sliding, Sempervivum tectorum.For the root and rhizome of samphire Angelica pubescens, Angelica pubescens, Angelica dahurica, purple stem Radix Angelicae Pubescentis, Radix Heraclei hemsleyani, fur Radix Angelicae Pubescentis and Araliaceae Shi Cortex araliae chinensis.Nature and flavor: arduous, temperature.Return kidney, urinary bladder channel.Function cures mainly: dispel the wind, and victory is wet, cold expelling, pain relieving.Control anemofrigid-damp arthralgia, soreness of waist and knee joint, trick spasm and pain, chronic tracheitis, headache, toothache.
Caulis Piperis Kadsurae: be the rattan of Piperaceae plant pipex kadsura.Nature and flavor: arduous, tepor.GUIXIN, kidney channel.Function: wind-damp dispelling, the meridian dredging, regulates the flow of vital energy.Cure mainly: anemofrigid-damp arthralgia, articular instability, the contracture of muscle arteries and veins, lumbocrural pain, traumatic injury, asthma.
Folium Et Cacumen Murrayae: different name Radix Buddlejae Butterflybush, Murraya paniculata (L.) Jack., five li of perfume (or spice), Clausena excavata Burm.f., water Rohdea japonica Roth, tetramerous jasminorange leaf, the moon Fructus Citri tangerinae.For the stem and leaf of rutaceae Folium Et Cacumen Murrayae.Nature and flavor: acrid in the mouth, micro-hardship, warm in nature.GUIXIN, liver, lung meridian.Function cures mainly: circulation of qi promoting, invigorates blood circulation, and dispels the wind, dehumidifying, and has analgesia to act on.Main gastral cavity abdomen pain due to disorder of QI, tumbling and swelling, Jie skin ulcer, skin pruritus.
Fructus Evodiae: different name Fructus Evodiae, Zuo Li.For the immature fruit of rutaceae Fructus Evodiae.Nature and flavor: arduous, temperature.Return Liver Channel, stomach warp.Function cures mainly: warming middle-JIAO, and pain relieving is regulated the flow of vital energy, dampness.Stopping vomiting tells acid regurgitation, headache due to JUE YIN disorder, and the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.
Herba Taxilli: as if the parasitic tree of another name, parasitic grass, residence wood child etc.For the branch and leaf of Loranthaceae plant Herba Visci, Herba Taxilli or hair leaf parasitism etc.Nature and flavor: bitter sweet are flat.Return liver, kidney channel.Function cures mainly: invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, vessel conditioning, beneficial blood, antiabortive.Main soreness of waist and knee joint, muscles and bones flaccidity is weak, hemiplegia, beriberi, rheumatic arthralgia, vaginal bleeding during pregnancy metrorrhagia, puerperal galactostasis.
Caulis Spatholobi: different name Radix seu Caulis Verntilaginis Leiocarpae.For the rattan of leguminous plant spatholobus suberectus, Mucuna birdwoodiana, fragrant flower Moghania fluminalis(C. B. Clarke) Li rattan or bright leaf Moghania fluminalis(C. B. Clarke) Li rattan.Nature and flavor: bitter sweet, temperature.GUIXIN, spleen channel.Function cures mainly: invigorate blood circulation, relaxing muscles and tendons.Control soreness of waist and knee joint, paralysis and numbness, menoxenia.
Carnis Rapanae thomasianae Octopus ocellatus Gray: nature and flavor: salty, tepor.Return stomach, liver, kidney channel.Function cures mainly: dehumidifying, antacid, arresting bleeding and healing up ulcer.Treat for stomachache acid regurgitation, and haematemesis, epistaxis, hematemesis, have blood in stool, bleeding not during menses, amenorrhea due to blood depletion, Fu Tong mass in the abdomen, dysentery, the rotten skin ulcer of the erosion of the vulva.
Celastrus orbiculatus Thunb.: different name is crossed mountain phoenix, hung wide whip, XIANGLONGCAO, Cortex Ampelopsis Aconitifoliae Radicis, Lobaria pulmonaria (L.) Hoffm., Rhizoma Dioscoreae Nipponicae, old tendon Bovis seu Bubali etc.For the rattan of Celastraceae plant Celastrus orbiculatus Thunb..Nature and flavor: micro-pungent, temperature, nontoxic (" conventional Chinese herbal medicine formula ").Function cures mainly: wind-damp dispelling, network of invigorating blood circulation.Control bones and muscles pain, numb limbs and tense tendons, infantile convulsion, acute filthy disease, dysentery.
Pyritum: be Natural pyrite, main containing ferrous disulfide (FeS
2).Nature and flavor: arduous are flat.Return kidney, Liver Channel.Function cures mainly: eliminating stasis to stop pain, reunion of bone.Control traumatic injury, tendon breaking is fractured, and blood stasis pain, gathers, goiter, skin infection, scalds.
Chinese medicine composition of the present invention is based on the pathogenetic research of the deep layer of inventor to scapulohumeral periarthritis and Therapeutic Principle thereof, simultaneously according to inventor's clinical experience and pharmaceutical research achievement for many years, filter out expelling wind and removing dampness, cold expelling circulation of qi promoting, soothing the channels and quicking the network vessels, the crude drug of promoting blood circulation and stopping pain, forms according to certain weight proportion prescription.
When adding the crude drug of following weight portion in above-mentioned Chinese medicine composition, there is the effect of better dispeling the wind, dehumidifying: Fructus glochidionis puberi(Herba Glochidii Puberi) 5-12 Fen, Herba Siegesbeckiae 5-12 part, Radix Stephaniae Tetrandrae 4-10 part, Radix Gentianae Macrophyllae 4-10 part; Preferably, the weight portion of each raw material is: Fructus glochidionis puberi(Herba Glochidii Puberi) 10 Fen, Herba Siegesbeckiae 10 parts, Radix Stephaniae Tetrandrae 8 parts, Radix Gentianae Macrophyllae 6 parts.
Fructus glochidionis puberi(Herba Glochidii Puberi): different name abacus bead, calabazilla, green pepper, blood Fructus Chaenomelis etc.For the fruit of euphorbia plant Fructus glochidionis puberi(Herba Glochidii Puberi).Be used as medicine with root and leaf.Root can be adopted the whole year, cleans, dries.Nature and flavor: micro-hardship, puckery, cool.Function cures mainly: clearing away heat-damp and promoting diuresis, dispelling, collateral-activating.For cold, fever, throat pain, malaria, acute gastroenteritis, dyspepsia, dysentery, rheumatic arthritis, traumatic injury, leucorrhea, dysmenorrhea.
Herba Siegesbeckiae: Yi Ming Herba Siegesbeckiae, fiery Xian, the pig cream certain kind of berries, Adeps Tigris, Canis familiaris L. cream etc.For the herb of feverfew Herba Siegesbeckiae, Herba Siegesbeckiae or siegesbeckia glabrescens Makino.Nature and flavor: bitter, cold.Return Liver Channel, spleen channel, kidney channel.Function cures mainly: wind-damp dispelling, relieving rigidity of muscles and joints, blood pressure lowering.Control quadriplegia, bones and muscles pain, weakness of the waist and knees, acute hepatitis, hypertension, furuncle swelling toxin, traumatic hemorrhage etc.
Radix Stephaniae Tetrandrae: different name is dissociated, carry monarch's row, Radix Stephaniae Tetrandrae.For the root of menispermaceous plants Radix stephaniae tetrandrae, Radix cocculi laurifolii or aristolochiaceae plant Radix Aristolochiae Fangchi, radix aristolochiae heterophyllae.Nature and flavor: bitter, cold.Return bladder, spleen, kidney channel.Function cures mainly: row water, rushes down damp-heat in lower-JIAO.Harness the river swollen tympanites, hygropyretic beriberi, brothers' spasm and pain, tinea scabies swells.
Radix Gentianae Macrophyllae: different name different name Qin glue, the Qin entangle, Qin's pawl, Radix Gentianae Marcrophyllae, a left side are turned round, leftly twist root etc.For the root of gentianaceae plant gentiana macrophylla, thick stem Radix Gentianae and Tibet Radix Gentianae.Nature and flavor: toil are flat.Return stomach warp, Liver Channel, gallbladder meridian.Function cures mainly: Eradicates wind dehumidifies, and blood relaxing muscles and tendons network, clearing away heat and promoting diuresis.Dispelling the wind and dampness pathogens arthralgia pain, muscles and bones contracture, has blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.
There is effect of better cold expelling, circulation of qi promoting: Lignum Sappan 5-12 part, Rhizoma Alpiniae Officinarum 5-12 part, Caulis Lonicerae 4-10 part, Rhizoma Curcumae Longae 3-8 part when adding the crude drug of following weight portion in the present invention in drug composition; Preferably, the weight portion of each raw material is: Lignum Sappan 10 parts, Rhizoma Alpiniae Officinarum 8 parts, Caulis Lonicerae 7 parts, 6 parts, Rhizoma Curcumae Longae.
Lignum Sappan: different name Soviet Union a tree, used in making timber for boats, the Soviet side, lignum sappan, lowland swamp wood, palm fibre wood, Ramulus et Folium Bischofiae Javanicae, red bavin.For the dry duramen of leguminous plant Lignum Sappan (Caesal pinia sappanL.).Nature and flavor: Gan Xian are flat.GUIXIN, Liver Channel.Function cures mainly: promoting the circulation of blood, removing blood stasis with potent drugs, detumescence, pain relieving.Control married woman's vim and vigour cardiac and abdominal pain, amenorrhea, postnatal blood stasis distending pain dyspnea with rapid respiration, dysentery, carbuncle, flutter and damage that the stasis of blood is stagnant has a pain, tetanus.
Rhizoma Alpiniae Officinarum: the little Rhizoma Alpiniae Officinarum of different name, Rhizoma Alpiniae Officinarum, quite Rhizoma Zingiberis Recens, Fructus Citri Sarcodactylis root, current chart Rhizoma Zingiberis Recens.For the rhizome of zingiberaceous plant Rhizoma Alpiniae Officinarum.Nature and flavor: pungent, heat.Return spleen, stomach warp.Function cures mainly: stomach warming, dispels the wind, cold expelling, circulation of qi promoting, pain relieving.Control taste invasion by pathogenic cold, coldness and pain in the epigastrium, vomiting is had loose bowels, dysphagia and regurgitation, dyspepsia, miasma disease, cold addiction.
Caulis Lonicerae: different name Caulis Lonicerae, Lao Wengxu, vine of Flos Lonicerae, two flower saplings etc.For the stem and leaf of caprifoliaceae plant Radix Ophiopogonis.Autumn, season in winter two tap, and dry.Nature and flavor: sweet, cold.GUIXIN, lung meridian.Function cures mainly: heat clearing away, removing toxic substances, dredging collateral.Control epidemic febrile disease heating, toxic-heat and blood stasis, infectious hepatitis, carbuncle sore tumefacting virus, bones and muscles pain.
Rhizoma Curcumae Longae: different name tripod is fragrant, Dioscorea zingiberensis.For the rhizome of zingiberaceous plant Rhizoma Curcumae Longae or Radix Curcumae.Nature and flavor: arduous, temperature.Return spleen, Liver Channel.Function cures mainly: removing blood stasis, and circulation of qi promoting is stimulated the menstrual flow, pain relieving.Control trusted subordinate's feeling of fullness distending pain, brachialgia ， mass in the abdomen, women's blood stasis amenorrhea, puerperal, the stasis of blood stopped stomachache, injury from falling down, carbuncle.
In side of the present invention, each medicine compatibility plays expelling wind and removing dampness together altogether, cold expelling circulation of qi promoting, soothing the channels and quicking the network vessels, effect of promoting blood circulation and stopping pain, Chinese medicine composition of the present invention is for scapulohumeral periarthritis treating both the principal and secondary aspects of a disease, and clinical observation on the therapeutic effect confirms, Chinese medicine composition of the present invention is reliable for scapulohumeral periarthritis determined curative effect, true.Chinese medicine composition of the present invention is nontoxic, safe and reliable, has no adverse reaction after taking, Clinical practice safety.
The present invention's each taste crude drug used can be bought at pharmacy and obtain.
Medicine activity component of the present invention can add various adjuvants required when preparing different dosage form, such as disintegrating agent, lubricant, adhesive etc., the suitable clinical preparation of any one is prepared into the method for Chinese medicinal of routine, as oral formulations or external preparation, described oral formulations can be pill, powder, granule, capsule, tablet, oral liquid, drop pill etc.; External preparation used can unguentum, washing liquid, liniment etc.
A kind of preparation method of Chinese medicine composition of the present invention: after being taken by described weight by each crude drug of the present invention, pulverize, sieve (can be such as 100-300 mesh sieve), to obtain final product.Certainly, after also each crude drug can being pulverized, add the adjuvant needed for preparations shaping or excipient, be conventionally prepared into capsule, tablet or pill.
The another kind of preparation method of Chinese medicine composition of the present invention: take each crude drug by described weight portion; By each crude drug soak by water, merge decoction liquor, filter, filtrate is condensed into clear paste, and add adjuvant or the excipient of preparations shaping, preparations shaping, to obtain final product.
The usage of Chinese medicine composition of the present invention and consumption: dosage of the present invention depends on the factor such as age, health status of concrete dosage form, patient.As guidance: usage and dosage: capsule, each capsule content 0.2 gram of crude drug, oral 1 to 3 at every turn, 3 times on the one 10 days is a course for the treatment of.
Detailed description of the invention
The present invention is further described below in conjunction with specific embodiment; these embodiments are only exemplary; what those skilled in the art should understand that is; can modify to the details of technical solution of the present invention and form lower without departing from the spirit and scope of the present invention or replace, but these amendments and replacement all fall within the scope of protection of the present invention.
The preparation of embodiment 1 capsule
Each crude drug (unit: g): Radix Angelicae Pubescentis 15, Caulis Piperis Kadsurae 15, Folium Et Cacumen Murrayae 15, Fructus Evodiae 15, Herba Taxilli 12, Caulis Spatholobi 12, Carnis Rapanae thomasianae Octopus ocellatus Gray 10, Celastrus orbiculatus Thunb. 10, Pyritum 5 is taken by following weight; Above-mentioned each crude drug is decocted with water secondary, and add water 4 times of weight for the first time, decocts 2 hours, and add water 5 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.17-1.19(60 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 2 capsule
Each crude drug (unit: g): Radix Angelicae Pubescentis 35, Caulis Piperis Kadsurae 35, Folium Et Cacumen Murrayae 35, Fructus Evodiae 35, Herba Taxilli 30, Caulis Spatholobi 30, Carnis Rapanae thomasianae Octopus ocellatus Gray 25, Celastrus orbiculatus Thunb. 25, Pyritum 10 is taken by following weight; Above-mentioned each crude drug is decocted with water secondary, and add water 6 times of weight for the first time, decocts 2 hours, and add water 4 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.17-1.19(60 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 3 capsule
Each crude drug (unit: g): Radix Angelicae Pubescentis 20, Caulis Piperis Kadsurae 20, Folium Et Cacumen Murrayae 20, Fructus Evodiae 20, Herba Taxilli 16, Caulis Spatholobi 16, Carnis Rapanae thomasianae Octopus ocellatus Gray 12, Celastrus orbiculatus Thunb. 12, Pyritum 7 is taken by following weight; Above-mentioned each crude drug is decocted with water secondary, and add water 4 times of weight for the first time, decocts 2 hours, and add water 5 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.30-1.35(55 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 4 capsule
Each crude drug (unit: g): Radix Angelicae Pubescentis 15, Caulis Piperis Kadsurae 15, Folium Et Cacumen Murrayae 15, Fructus Evodiae 15, Herba Taxilli 12, Caulis Spatholobi 12, Carnis Rapanae thomasianae Octopus ocellatus Gray 10, Celastrus orbiculatus Thunb. 10, Pyritum 5, Fructus glochidionis puberi(Herba Glochidii Puberi) 5, Herba Siegesbeckiae 5, Radix Stephaniae Tetrandrae 4, Radix Gentianae Macrophyllae 4 is taken by following weight; Above-mentioned each crude drug is decocted with water secondary, and add water 4 times of weight for the first time, decocts 2 hours, and add water 5 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.30-1.35(55 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 5 capsule
Each crude drug (unit: g): Radix Angelicae Pubescentis 35, Caulis Piperis Kadsurae 35, Folium Et Cacumen Murrayae 35, Fructus Evodiae 35, Herba Taxilli 30, Caulis Spatholobi 30, Carnis Rapanae thomasianae Octopus ocellatus Gray 25, Celastrus orbiculatus Thunb. 25, Pyritum 10, Fructus glochidionis puberi(Herba Glochidii Puberi) 12, Herba Siegesbeckiae 12, Radix Stephaniae Tetrandrae 10, Radix Gentianae Macrophyllae 10 is taken by following weight; Above-mentioned each crude drug is decocted with water secondary, and add water 6 times of weight for the first time, decocts 2 hours, and add water 4 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.17-1.19(60 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 6 capsule
Each crude drug (unit: g): Radix Angelicae Pubescentis 20, Caulis Piperis Kadsurae 20, Folium Et Cacumen Murrayae 20, Fructus Evodiae 20, Herba Taxilli 16, Caulis Spatholobi 16, Carnis Rapanae thomasianae Octopus ocellatus Gray 12, Celastrus orbiculatus Thunb. 12, Pyritum 7, Fructus glochidionis puberi(Herba Glochidii Puberi) 10, Herba Siegesbeckiae 10, Radix Stephaniae Tetrandrae 8, Radix Gentianae Macrophyllae 6 is taken by following weight; Above-mentioned each crude drug is decocted with water secondary, and add water 6 times of weight for the first time, decocts 2 hours, and add water 4 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.17-1.19(60 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverizing adds appropriate amount of ethanol and makes granule, and dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 7 capsule
Each crude drug (unit: g): Radix Angelicae Pubescentis 15, Caulis Piperis Kadsurae 15, Folium Et Cacumen Murrayae 15, Fructus Evodiae 15, Herba Taxilli 12, Caulis Spatholobi 12, Carnis Rapanae thomasianae Octopus ocellatus Gray 10, Celastrus orbiculatus Thunb. 10, Pyritum 5, Lignum Sappan 5, Rhizoma Alpiniae Officinarum 5, Caulis Lonicerae 4, Rhizoma Curcumae Longae 3 is taken by following weight; Above-mentioned each crude drug is decocted with water secondary, and add water 6 times of weight for the first time, decocts 2 hours, and add water 4 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.17-1.19(60 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 8 capsule
Each crude drug (unit: g): Radix Angelicae Pubescentis 35, Caulis Piperis Kadsurae 35, Folium Et Cacumen Murrayae 35, Fructus Evodiae 35, Herba Taxilli 30, Caulis Spatholobi 30, Carnis Rapanae thomasianae Octopus ocellatus Gray 25, Celastrus orbiculatus Thunb. 25, Pyritum 10, Lignum Sappan 12, Rhizoma Alpiniae Officinarum 12, Caulis Lonicerae 10, Rhizoma Curcumae Longae 8 is taken by following weight; Above-mentioned each crude drug is decocted with water secondary, and add water 6 times of weight for the first time, decocts 2 hours, and add water 4 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.17-1.19(60 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 9 capsule
Each crude drug (unit: g): Radix Angelicae Pubescentis 20, Caulis Piperis Kadsurae 20, Folium Et Cacumen Murrayae 20, Fructus Evodiae 20, Herba Taxilli 16, Caulis Spatholobi 16, Carnis Rapanae thomasianae Octopus ocellatus Gray 12, Celastrus orbiculatus Thunb. 12, Pyritum 7, Lignum Sappan 10, Rhizoma Alpiniae Officinarum 8, Caulis Lonicerae 7, Rhizoma Curcumae Longae 6 is taken by following weight; Above-mentioned each crude drug is decocted with water secondary, and add water 6 times of weight for the first time, decocts 2 hours, and add water 4 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.17-1.19(60 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The clinical observation on the therapeutic effect test of test example 1 traditional Chinese medicine composition for treating scapulohumeral periarthritis of the present invention
One, physical data: 180 routine patients all meet the diagnostic criteria of scapulohumeral periarthritis, 25 ~ 75 years old age, average 45 years old.Patient is divided into 3 groups at random, often organizes 60 examples; 3 groups of no significant differences on sex, age, the course of disease and coincident with severity degree of condition.
Two, trial drug
Medicine prepared by embodiment of the present invention 1-9.
Three, Therapeutic Method
180 routine patients are divided into 3 groups at random, that is: test 1 group, test 2 groups and test 3, often organize each 60 examples, testing 1 group adopts the capsule prepared by embodiment 1-3 to treat, testing 2 groups adopts the capsule prepared by embodiment 4-6 to treat, testing 3 groups adopts the capsule prepared by embodiment 7-9 to treat; Oral, one time 3 (0.2g crude drug/grain), 3 times on the one 10 days is a course for the treatment of, treats 4 courses for the treatment of altogether; Period in a medicine withdraws other related drugs and other treatment.
Four, efficacy assessment standard
Recovery from illness: pain disappears, shoulder joint function recovers normal, around without tenderness and sensitive spot; Effective: pain substantially disappears or obviously alleviates, the energy-conservation abduction of shoulder joint, after stretch 70 °; Effective: shoulder can touch pressure pain point, the energy-conservation abduction of shoulder joint, after stretch 50 °; Invalid: the state of an illness is unchanged.
Five, clinical observation result
Clinical observation result is in table 1.
The clinical observation on the therapeutic effect result of the test of table 1 traditional Chinese medicine composition for treating scapulohumeral periarthritis of the present invention
Clinical observation on the therapeutic effect result shows, Chinese medicine composition of the present invention has significant curative effect for scapulohumeral periarthritis patient; Safety observations find, do not observe any clinical adverse, show Chinese medicine composition clinical practice of the present invention safely, have no side effect.
Claims (7)
1. the Chinese medicine composition of a cure scapulohumeral periarthritis, it is characterized in that, be made up of each crude drug of following weight portion: Radix Angelicae Pubescentis 15-35 part, Caulis Piperis Kadsurae 15-35 part, Folium Et Cacumen Murrayae 15-35 part, Fructus Evodiae 15-35 part, Herba Taxilli 12-30 part, Caulis Spatholobi 12-30 part, Carnis Rapanae thomasianae Octopus ocellatus Gray 10-25 part, Celastrus orbiculatus Thunb. 10-25 part and Pyritum 5-10 part.
2. according to Chinese medicine composition according to claim 1, it is characterized in that, the weight portion of each crude drug is: Radix Angelicae Pubescentis 15-25 part, Caulis Piperis Kadsurae 15-25 part, Folium Et Cacumen Murrayae 15-25 part, Fructus Evodiae 15-25 part, Herba Taxilli 12-20 part, Caulis Spatholobi 12-20 part, Carnis Rapanae thomasianae Octopus ocellatus Gray 10-15 part, Celastrus orbiculatus Thunb. 10-15 part, Pyritum 5-8 part.
3. according to Chinese medicine composition according to claim 2, it is characterized in that, the weight portion of each crude drug is: Radix Angelicae Pubescentis 20 parts, Caulis Piperis Kadsurae 20 parts, Folium Et Cacumen Murrayae 20 parts, Fructus Evodiae 20 parts, Herba Taxilli 16 parts, Caulis Spatholobi 16 parts, Carnis Rapanae thomasianae Octopus ocellatus Gray 12 parts, Celastrus orbiculatus Thunb. 12 parts, Pyritum 7 parts.
4. a Chinese medicine composition for cure scapulohumeral periarthritis, is made up of each crude drug of following weight portion: Radix Angelicae Pubescentis 15-35 part, Caulis Piperis Kadsurae 15-35 part, Folium Et Cacumen Murrayae 15-35 part, Fructus Evodiae 15-35 part, Herba Taxilli 12-30 part, Caulis Spatholobi 12-30 part, Carnis Rapanae thomasianae Octopus ocellatus Gray 10-25 part, Celastrus orbiculatus Thunb. 10-25 part, Pyritum 5-10 part, Fructus glochidionis puberi(Herba Glochidii Puberi) 5-12 part, Herba Siegesbeckiae 5-12 part, Radix Stephaniae Tetrandrae 4-10 part and Radix Gentianae Macrophyllae 4-10 part.
5. according to Chinese medicine composition according to claim 4, it is characterized in that, the weight portion of each crude drug is: Radix Angelicae Pubescentis 20 parts, Caulis Piperis Kadsurae 20 parts, Folium Et Cacumen Murrayae 20 parts, Fructus Evodiae 20 parts, Herba Taxilli 16 parts, Caulis Spatholobi 16 parts, Carnis Rapanae thomasianae Octopus ocellatus Gray 12 parts, Celastrus orbiculatus Thunb. 12 parts, Pyritum 7 parts, Fructus glochidionis puberi(Herba Glochidii Puberi) 10 Fen, Herba Siegesbeckiae 10 parts, Radix Stephaniae Tetrandrae 8 parts, Radix Gentianae Macrophyllae 6 parts.
6. prepare a method for claim 1-5 Chinese medicine composition described in any one, comprise the following steps:
(1), each crude drug is taken by described weight proportion;
(2), by each crude drug soak by water, merge decoction liquor, filter, filtrate is condensed into clear paste, adds the adjuvant of preparations shaping, preparations shaping, to obtain final product.
7. claim 1-5 Chinese medicine composition described in any one is preparing the purposes in cure scapulohumeral periarthritis medicine.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1895642A (en) * | 2005-07-12 | 2007-01-17 | 侯保君 | Traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain and preparation method thereof |
| CN101181413A (en) * | 2007-11-21 | 2008-05-21 | 北京中科雍和医药技术有限公司 | Pharmaceutical combination for curing chronic rheumatic arthritis and scapulohumeral periarthritis as well as preparation method |
| CN102309570A (en) * | 2010-07-01 | 2012-01-11 | 王峰 | Traditional Chinese medicine (TCM) prescription for treating scapulohumeral periarthritis |
| CN102552637A (en) * | 2012-01-16 | 2012-07-11 | 金丽霞 | Chinese medicinal composition for treating scapulohumeral periarthritis and preparation method thereof |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1895642A (en) * | 2005-07-12 | 2007-01-17 | 侯保君 | Traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain and preparation method thereof |
| CN101181413A (en) * | 2007-11-21 | 2008-05-21 | 北京中科雍和医药技术有限公司 | Pharmaceutical combination for curing chronic rheumatic arthritis and scapulohumeral periarthritis as well as preparation method |
| CN102309570A (en) * | 2010-07-01 | 2012-01-11 | 王峰 | Traditional Chinese medicine (TCM) prescription for treating scapulohumeral periarthritis |
| CN102552637A (en) * | 2012-01-16 | 2012-07-11 | 金丽霞 | Chinese medicinal composition for treating scapulohumeral periarthritis and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| "中西医结合治疗类风湿关节炎疗效观察";曹向东;《现代中西医结合杂志》;20081231;第17卷(第1期);第5-7页 * |
| "肩周炎的中医治疗近况";王星田;《陕西中医》;19911231(第6期);第282-283页 * |
| "肩周炎的中医药治疗进展";刘志刚;《中医药信息》;19911231(第2期);第17-21页 * |
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