CN103381216A - Traditional Chinese medicine composite for curing periarthritis of shoulder and preparation method thereof - Google Patents
Traditional Chinese medicine composite for curing periarthritis of shoulder and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composite for curing periarthritis of shoulder and a preparation method thereof. The traditional Chinese medicine composite comprises following components in parts by weight: 15 to 35 parts of levisticum, 15 to 35 parts of caulis piperis kadsurae, 15 to 35 parts of murraya paniculata, 15 to 35 parts of evodia, 12 to 30 parts of taxillus, 12 to 30 parts of spatholobus stem, 10 to 25 parts of cuttlebone, 10 to 25 parts of celastrus orbiculatus and 5 to 10 parts of natural copper. The traditional Chinese medicine composition can be prepared into a medicine preparation, which can be accepted by any clinic, through traditional Chinese medicine preparation methods. The traditional Chinese medicine composition has the functions of dispelling wind, eliminating dampness, dispelling cold, promoting the circulation of Qi, relaxing tendons, activating collaterals, and promoting blood circulation to arrest pain. Clinic effects have shown that the traditional Chinese medicine composition has a definite and reliable curative effect on periarthritis of shoulder, treats both symptoms and root causes, is safe on clinical application and has no toxic or side effects.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to Chinese medicine composition of a kind of cure scapulohumeral periarthritis and preparation method thereof, belong to the treatment by Chinese herbs field of scapulohumeral periarthritis.
Background technology
The scapulohumeral periarthritis full name is scapulohumeral periarthritis, is take shoulder arthralgia and inconvenient activity as the common disease of cardinal symptom, is commonly called as solidifying shoulder, scapulohumeral periarthritis or congealed shoulder.Because the flesh thoraxes of shoulder joint surrounding tissue, synovial bursa etc. are subjected to due to freezing, wound, infection, be how the chronic aseptic inflammation of the soft tissues such as muscle around shoulder joint, tendon, synovial bursa and joint capsule, many patients are caused by rheumatism.Its cardinal symptom is neck shoulder constant pain, and Ipsilateral upper limb lifting, rotation, swing are limited, meets wind and meets cold sensation heavy dull pain is arranged.As untimely treatment, with the passing of time delay can make joint accretion, and the Ipsilateral upper limb attenuates, the unable disuse atrophy that even forms.This disease is more common in the middle age about 50 years old, and the young and the old also has generation.Patient's hurt like hell when serious that shows effect is lain awake all night.
Modern Chinese medicine is thought morbidity and the insufficiency of vital energy and blood of scapulohumeral periarthritis, and affection of exogenous wind-cold is wet and the sprain and contusion impairment caused by overstrain is relevant, injures shoulder muscle arteries and veins, causes QI and blood obstructed and pain, bone growth promoting numbness then.In the traditional Chinese medical science classic doctor nationality " Plain Questions numbness opinion ", the classification such as rheumatism involving the bone, muscular rheumatism, BI-syndrome involved the blood vessels, BI-syndrome related to skin are arranged, think that its cause of disease and wind and cold are wet relevant.Propose first its morbidity in close relations with wound in " Ling Shu Miraculous Pivot or Divine Axis harmful wind " piece of writing, think that the rear stagnant blood of wound stops gathering between muscle muscles and bones, QI-blood circulation is not smooth, is subject to wind-cold damp pathogen and invades, and stagnant blood and exopathogen invasion and attack are sent out and are arthromyodynia.At Sui-Tang bines, recognize further that again its morbidity is relevant with the impairment caused by overstrain insufficiency of vital energy and blood.Record in " celestial being is awarded the treating trauma and fracture secret recipe ": " muscles and bones, shoulder and back ache " in spite of wound.Pointed out that itself and wound have definite relation.To Qing Dynasty's Golden Mirror of Medicine summed up thousands of year over to the understanding of shoulder brachialgia, point out the syndromes such as pain in the shoulder and back has blockage of meridian-QI, the deficiency of vital energy, blood deficiency and double wind, the expectorant of holding concurrently.Claim primary disease " scapulohumeral periarthritis ", " scapulohumeral periarthritis " etc. in Chinese medicine, belong to the arthromyodynia category.How with age body is empty, and wind-cold damp pathogen is taken advantage of a weak point, and causes through BI-syndrome involved the blood vessels to hinder; Or tumbling down damage, in blood stasis stayed, QI and blood was not all right, and the muscles along the regular meridians effect is not normal and the road causes primary disease.
At present, the Chinese patent medicine that is used for the treatment of scapulohumeral periarthritis all in various degree exist slow, the defective such as curative effect is remarkable not that takes effect, have much room for improvement.
Summary of the invention
That technical problem to be solved by this invention is that overcome existing cure scapulohumeral periarthritis existing takes effect is slow, curative effect not significantly, the defective such as toxic and side effects is large, the Chinese medicine composition of the cure scapulohumeral periarthritis that provide a kind of instant effect, determined curative effect, has no side effect;
Another technical problem to be solved by this invention is to provide a kind of method for preparing above-mentioned Chinese medicine composition.
Above-mentioned technical problem to be solved by this invention is achieved through the following technical solutions:
A kind of Chinese medicine composition of cure scapulohumeral periarthritis comprises that each component of following weight portion forms: Radix Angelicae Pubescentis, Caulis Piperis Kadsurae, Folium Et Cacumen Murrayae, Fructus Evodiae, Herba Taxilli, Caulis Spatholobi, Carnis Rapanae thomasianae Octopus ocellatus Gray, Celastrus orbiculatus Thunb., Pyritum.
Preferably, the weight portion of each component is: Radix Angelicae Pubescentis 15-35 part, Caulis Piperis Kadsurae 15-35 part, Folium Et Cacumen Murrayae 15-35 part, Fructus Evodiae 15-35 part, Herba Taxilli 12-30 part, Caulis Spatholobi 12-30 part, Carnis Rapanae thomasianae Octopus ocellatus Gray 10-25 part, Celastrus orbiculatus Thunb. 10-25 part, Pyritum 5-10 part.
More select, the weight portion of each component is: Radix Angelicae Pubescentis 15-25 part, Caulis Piperis Kadsurae 15-25 part, Folium Et Cacumen Murrayae 15-25 part, Fructus Evodiae 15-25 part, Herba Taxilli 12-20 part, Caulis Spatholobi 12-20 part, Carnis Rapanae thomasianae Octopus ocellatus Gray 10-15 part, Celastrus orbiculatus Thunb. 10-15 part, Pyritum 5-8 part.
Most preferred, the weight portion of each component is: 20 parts of Radix Angelicae Pubescentiss, 20 parts of Caulis Piperis Kadsuraes, 20 parts of Folium Et Cacumen Murrayae, 20 parts of Fructus Evodiaes, 16 parts of Herba Taxillis, 16 parts of Caulis Spatholobis, 12 parts of Carnis Rapanae thomasianae Octopus ocellatus Grays, 12 parts of Celastrus orbiculatus Thunb.s, 7 parts of Pyritums.
Radix Angelicae Pubescentis: different name is solely shaken grass, only sliding, Sempervivum tectorum.Root and rhizome for samphire Angelica pubescens, Angelica pubescens, Xingan's Radix Angelicae Dahuricae, purple stem Radix Angelicae Pubescentis, Radix Heraclei hemsleyani, fur Radix Angelicae Pubescentis and Araliaceae Shi Yong Cortex araliae chinensis.Nature and flavor: arduous, temperature.Return kidney, urinary bladder channel.Function cures mainly: dispel the wind, victory is wet, cold expelling, pain relieving.Control anemofrigid-damp arthralgia, soreness of waist and knee joint, trick spasm and pain, chronic tracheitis, headache, toothache.
Caulis Piperis Kadsurae: be the rattan of Piperaceae plant pipex kadsura.Nature and flavor: arduous, tepor.GUIXIN, kidney channel.Function: wind-damp dispelling, the meridian dredging is regulated the flow of vital energy.Cure mainly: anemofrigid-damp arthralgia, articular instability, the contracture of muscle arteries and veins, lumbocrural pain, traumatic injury, asthma.
Folium Et Cacumen Murrayae: different name Radix Buddlejae Butterflybush, Murraya paniculata (L.) Jack., five li perfume (or spice), Clausena excavata Burm.f., water Rohdea japonica Roth, tetramerous jasminorange leaf, month Fructus Citri tangerinae.Stem and leaf for the rutaceae Folium Et Cacumen Murrayae.Nature and flavor: acrid in the mouth, little hardship, warm in nature.GUIXIN, liver, lung meridian.Function cures mainly: circulation of qi promoting, invigorate blood circulation, and dispel the wind, dehumidifying, and the analgesia effect is arranged.Main gastral cavity abdomen pain due to disorder of QI, tumbling and swelling, Jie skin ulcer, skin pruritus.
Fructus Evodiae: different name Fructus Evodiae, left power.Immature fruit for the rutaceae Fructus Evodiae.Nature and flavor: arduous, temperature.Return Liver Channel, stomach warp.Function cures mainly: warming middle-JIAO, pain relieving is regulated the flow of vital energy, dampness.Stopping vomiting is told acid regurgitation, headache due to JUE YIN disorder, and the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.
Herba Taxilli: as if the parasitism that has another name called is set, parasitism is careless, wooden child etc. resides.Branch and leaf for Loranthaceae plant Herba Visci, Herba Taxilli or hair leaf parasitism etc.Nature and flavor: bitter sweet, flat.Return liver, kidney channel.Function cures mainly: invigorating the liver and kidney, and bone and muscle strengthening, wind-damp dispelling, vessel conditioning, beneficial blood, antiabortive.Main soreness of waist and knee joint, hemiplegia a little less than the muscles and bones flaccidity, beriberi, rheumatic arthralgia, the vaginal bleeding during pregnancy metrorrhagia, puerperal galactostasis.
Caulis Spatholobi: different name Radix seu Caulis Verntilaginis Leiocarpae.Rattan for leguminous plant spatholobus suberectus, Mucuna birdwoodiana, fragrant flower Moghania fluminalis(C. B. Clarke) Li rattan or bright leaf Moghania fluminalis(C. B. Clarke) Li rattan.Nature and flavor: bitter sweet, temperature.GUIXIN, spleen channel.Function cures mainly: invigorates blood circulation, and Shujin.Control soreness of waist and knee joint, paralysis and numbness, menoxenia.
Carnis Rapanae thomasianae Octopus ocellatus Gray: nature and flavor: salty, tepor.Return stomach, liver, kidney channel.Function cures mainly: dehumidifying, antacid, arresting bleeding and healing up ulcer.The acid regurgitation that treats for stomachache, haematemesis, epistaxis, hematemesis are had blood in stool, bleeding not during menses, amenorrhea due to blood depletion, Fu Tong mass in the abdomen, dysentery, the rotten skin ulcer of the erosion of the vulva.
Celastrus orbiculatus Thunb.: different name is crossed the mountain phoenix, is hung wide whip, XIANGLONGCAO, Cortex Ampelopsis Aconitifoliae Radicis, Lobaria pulmonaria (L.) Hoffm., Rhizoma Dioscoreae Nipponicae, old tendon Bovis seu Bubali etc.Rattan for Celastraceae plant Celastrus orbiculatus Thunb..Nature and flavor: little suffering, temperature, nontoxic (" Chinese herbal medicine formula commonly used ").Function cures mainly: wind-damp dispelling, the network of invigorating blood circulation.Control bones and muscles pain, numb limbs and tense tendons, infantile convulsion, acute filthy disease, dysentery.
Pyritum: be Natural pyrite, the main ferrous disulfide (FeS that contains
2).Nature and flavor: arduous, flat.Return kidney, Liver Channel.Function cures mainly: eliminating stasis to stop pain, reunion of bone.Control traumatic injury, the tendon breaking fracture, blood stasis pain is gathered, goiter, skin infection is scalded.
Chinese medicine composition of the present invention is based on the inventor to the pathogenetic research of the deep layer of scapulohumeral periarthritis and Therapeutic Principle thereof, simultaneously according to inventor clinical experience and pharmaceutical research achievement for many years, filter out expelling wind and removing dampness, the cold expelling circulation of qi promoting, soothing the channels and quicking the network vessels, the crude drug of promoting blood circulation and stopping pain forms according to certain weight proportion prescription.
Has better the effect of dispeling the wind, dehumidifying when adding the crude drug of following weight portion in above-mentioned Chinese medicine composition: Fructus glochidionis puberi(Herba Glochidii Puberi) 5-12 Fen, Herba Siegesbeckiae 5-12 part, Radix Stephaniae Tetrandrae 4-10 part, Radix Gentianae Macrophyllae 4-10 part; Preferably, the weight portion of each raw material is: Fructus glochidionis puberi(Herba Glochidii Puberi) 10 10 parts of Fen, Herba Siegesbeckiae, 8 parts of Radix Stephaniae Tetrandrae, 6 parts of Radix Gentianae Macrophyllae.
Fructus glochidionis puberi(Herba Glochidii Puberi): different name abacus bead, calabazilla, green pepper, blood Fructus Chaenomelis etc.Fruit for the euphorbia plant Fructus glochidionis puberi(Herba Glochidii Puberi).Be used as medicine with root and leaf.Root can be adopted the whole year, cleans, dries.Nature and flavor: little hardship, puckery, cool.Function cures mainly: clearing away heat-damp and promoting diuresis, dispelling, collateral-activating.Be used for cold, fever, throat pain, malaria, acute gastroenteritis, dyspepsia, dysentery, rheumatic arthritis, traumatic injury, leucorrhea, dysmenorrhea.
Herba Siegesbeckiae: Yi Ming Herba Siegesbeckiae, fiery Xian, the pig cream certain kind of berries, Adeps Tigris, Canis familiaris L. cream etc.Herb for feverfew Herba Siegesbeckiae, Herba Siegesbeckiae or siegesbeckia glabrescens Makino.Nature and flavor: bitter, cold.Return Liver Channel, spleen channel, kidney channel.Function cures mainly: wind-damp dispelling, relieving rigidity of muscles and joints, blood pressure lowering.Control quadriplegia, bones and muscles pain, weakness of the waist and knees, acute hepatitis, hypertension, furuncle swelling toxin, traumatic hemorrhage etc.
Radix Stephaniae Tetrandrae: monarch's row, Radix Stephaniae Tetrandrae are dissociated, carried to different name.Root for menispermaceous plants Radix stephaniae tetrandrae, Radix cocculi laurifolii or aristolochiaceae plant Radix Aristolochiae Fangchi, radix aristolochiae heterophyllae.Nature and flavor: hardship, cold.Return bladder, spleen, kidney channel.Function cures mainly: row water, rush down damp-heat in lower-JIAO.The swollen tympanites of harnessing the river, hygropyretic beriberi, brothers' spasm and pain, the tinea scabies is swollen.
Radix Gentianae Macrophyllae: different name different name Qin glue, the Qin entangle, Qin's pawl, and Radix Gentianae Marcrophyllae, a left side are turned round, the left root etc. of twisting.Root for gentianaceae plant gentiana macrophylla, thick stem Radix Gentianae and Tibet Radix Gentianae.Nature and flavor: toil, flat.Return stomach warp, Liver Channel, gallbladder meridian.Function cures mainly: the dehumidifying of Eradicates wind, and blood Shujin network, clearing away heat and promoting diuresis.The dispelling the wind and dampness pathogens arthralgia pain, the muscles and bones contracture is had blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.
Has the effect of better cold expelling, circulation of qi promoting when adding in the present invention the crude drug of following weight portion in drug composition: Lignum Sappan 5-12 part, Rhizoma Alpiniae Officinarum 5-12 part, Caulis Lonicerae 4-10 part, Rhizoma Curcumae Longae 3-8 part; Preferably, the weight portion of each raw material is: 10 parts of Lignum Sappans, 8 parts of Rhizoma Alpiniae Officinarums, 7 parts of Caulis Loniceraes, 6 parts, Rhizoma Curcumae Longae.
Lignum Sappan: different name Soviet Union a tree, used in making timber for boats, the Soviet side, lignum sappan, lowland swamp wood, palm fibre wood, Ramulus et Folium Bischofiae Javanicae, red bavin.Dry duramen for leguminous plant Lignum Sappan (Caesal pinia sappanL.).Nature and flavor: sweet salty, flat.GUIXIN, Liver Channel.Function cures mainly: promoting the circulation of blood, removing blood stasis with potent drugs, detumescence, pain relieving.Control married woman's vim and vigour cardiac and abdominal pain, amenorrhea, postnatal blood stasis distending pain dyspnea with rapid respiration, dysentery, carbuncle is flutterred and is damaged that the stasis of blood is stagnant has a pain, tetanus.
Rhizoma Alpiniae Officinarum: the little Rhizoma Alpiniae Officinarum of different name, Rhizoma Alpiniae Officinarum, rough Rhizoma Zingiberis Recens, Fructus Citri Sarcodactylis root, current chart Rhizoma Zingiberis Recens.Rhizome for the zingiberaceous plant Rhizoma Alpiniae Officinarum.Nature and flavor: suffering, heat.Return spleen, stomach warp.Function cures mainly: stomach warming, dispel the wind, and cold expelling, circulation of qi promoting, pain relieving.Control taste invasion by pathogenic cold, coldness and pain in the epigastrium, vomiting is had loose bowels, dysphagia and regurgitation, dyspepsia, miasma disease, cold addiction.
Caulis Lonicerae: different name Caulis Lonicerae, old man's palpus, vine of Flos Lonicerae, two flower saplings etc.Be the caprifoliaceae plant stem and leaf of Radix Ophiopogonis.Autumn, two seasons of winter tap, and dry.Nature and flavor: sweet, cold.GUIXIN, lung meridian.Function cures mainly: heat clearing away, detoxifcation, collateral dredging.Control the epidemic febrile disease heating, toxic-heat and blood stasis, infectious hepatitis, carbuncle sore tumefacting virus, bones and muscles pain.
Rhizoma Curcumae Longae: the different name tripod is fragrant, Dioscorea zingiberensis.Rhizome for zingiberaceous plant Rhizoma Curcumae Longae or Radix Curcumae.Nature and flavor: arduous, temperature.Return spleen, Liver Channel.Function cures mainly: removing blood stasis, circulation of qi promoting is stimulated the menstrual flow, pain relieving.Control trusted subordinate's feeling of fullness distending pain, brachialgia ， mass in the abdomen, women's blood stasis amenorrhea, puerperal, the stasis of blood was stopped stomachache, injury from falling down, carbuncle.
In side of the present invention, each medicine compatibility is played expelling wind and removing dampness, cold expelling circulation of qi promoting, soothing the channels and quicking the network vessels together altogether, the effect of promoting blood circulation and stopping pain, Chinese medicine composition of the present invention is for the scapulohumeral periarthritis treating both the principal and secondary aspects of a disease, and clinical observation on the therapeutic effect confirms, Chinese medicine composition of the present invention is reliable, true for the scapulohumeral periarthritis determined curative effect.Chinese medicine composition of the present invention is nontoxic, and is safe and reliable, has no adverse reaction after taking, clinical use safety.
The crude drug of respectively distinguishing the flavor of that the present invention is used can be bought at pharmacy and obtain.
Medicine activity component of the present invention can add various adjuvants required when preparing different dosage form, such as disintegrating agent, lubricant, adhesive etc., method of Chinese medicinal with routine is prepared into any suitable clinical preparation, as oral formulations or external preparation, described oral formulations can be pill, powder, granule, capsule, tablet, oral liquid, drop pill etc.; External preparation used can unguentum, washing liquid, liniment etc.
A kind of preparation method of Chinese medicine composition of the present invention: after each crude drug of the present invention is taken by described weight portion proportioning, pulverize, sieve (can be for example the 100-300 mesh sieve), and get final product.Certainly, after also each crude drug can being pulverized, add the required adjuvant of preparations shaping or excipient, be prepared into capsule, tablet or pill according to conventional method.
The another kind of preparation method of Chinese medicine composition of the present invention: take each crude drug by described weight portion; Each crude drug water is decocted, merge decoction liquor, filter, filtrate is condensed into clear paste, adds adjuvant or the excipient of preparations shaping, preparations shaping, and get final product.
The usage of Chinese medicine composition of the present invention and consumption: dosage of the present invention depends on the factors such as concrete dosage form, patient's age, health status.As guidance: usage and dosage: capsule, each capsule content 0.2 gram crude drug, each oral 1 to 3,3 times on the one, 10 days is a course for the treatment of.
The specific embodiment
Further describe the present invention below in conjunction with specific embodiment; these embodiment are only exemplary; what those skilled in the art should understand that is; can modify or replace details and the form of technical solution of the present invention lower without departing from the spirit and scope of the present invention, but these modifications and replacement all fall within the scope of protection of the present invention.
The preparation of embodiment 1 capsule
Take each crude drug (unit: g): Radix Angelicae Pubescentis 15, Caulis Piperis Kadsurae 15, Folium Et Cacumen Murrayae 15, Fructus Evodiae 15, Herba Taxilli 12, Caulis Spatholobi 12, Carnis Rapanae thomasianae Octopus ocellatus Gray 10, Celastrus orbiculatus Thunb. 10, Pyritum 5 by following weight; Above-mentioned each crude drug is decocted with water secondary, add for the first time 4 times of weight of water, decocted 2 hours, add for the second time 5 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.17-1.19(60 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 2 capsules
Take each crude drug (unit: g): Radix Angelicae Pubescentis 35, Caulis Piperis Kadsurae 35, Folium Et Cacumen Murrayae 35, Fructus Evodiae 35, Herba Taxilli 30, Caulis Spatholobi 30, Carnis Rapanae thomasianae Octopus ocellatus Gray 25, Celastrus orbiculatus Thunb. 25, Pyritum 10 by following weight; Above-mentioned each crude drug is decocted with water secondary, add for the first time 6 times of weight of water, decocted 2 hours, add for the second time 4 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.17-1.19(60 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 3 capsules
Take each crude drug (unit: g): Radix Angelicae Pubescentis 20, Caulis Piperis Kadsurae 20, Folium Et Cacumen Murrayae 20, Fructus Evodiae 20, Herba Taxilli 16, Caulis Spatholobi 16, Carnis Rapanae thomasianae Octopus ocellatus Gray 12, Celastrus orbiculatus Thunb. 12, Pyritum 7 by following weight; Above-mentioned each crude drug is decocted with water secondary, add for the first time 4 times of weight of water, decocted 2 hours, add for the second time 5 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.30-1.35(55 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 4 capsules
Take each crude drug (unit: g): Radix Angelicae Pubescentis 15, Caulis Piperis Kadsurae 15, Folium Et Cacumen Murrayae 15, Fructus Evodiae 15, Herba Taxilli 12, Caulis Spatholobi 12, Carnis Rapanae thomasianae Octopus ocellatus Gray 10, Celastrus orbiculatus Thunb. 10, Pyritum 5, Fructus glochidionis puberi(Herba Glochidii Puberi) 5, Herba Siegesbeckiae 5, Radix Stephaniae Tetrandrae 4, Radix Gentianae Macrophyllae 4 by following weight; Above-mentioned each crude drug is decocted with water secondary, add for the first time 4 times of weight of water, decocted 2 hours, add for the second time 5 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.30-1.35(55 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 5 capsules
Take each crude drug (unit: g): Radix Angelicae Pubescentis 35, Caulis Piperis Kadsurae 35, Folium Et Cacumen Murrayae 35, Fructus Evodiae 35, Herba Taxilli 30, Caulis Spatholobi 30, Carnis Rapanae thomasianae Octopus ocellatus Gray 25, Celastrus orbiculatus Thunb. 25, Pyritum 10, Fructus glochidionis puberi(Herba Glochidii Puberi) 12, Herba Siegesbeckiae 12, Radix Stephaniae Tetrandrae 10, Radix Gentianae Macrophyllae 10 by following weight; Above-mentioned each crude drug is decocted with water secondary, add for the first time 6 times of weight of water, decocted 2 hours, add for the second time 4 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.17-1.19(60 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 6 capsules
Take each crude drug (unit: g): Radix Angelicae Pubescentis 20, Caulis Piperis Kadsurae 20, Folium Et Cacumen Murrayae 20, Fructus Evodiae 20, Herba Taxilli 16, Caulis Spatholobi 16, Carnis Rapanae thomasianae Octopus ocellatus Gray 12, Celastrus orbiculatus Thunb. 12, Pyritum 7, Fructus glochidionis puberi(Herba Glochidii Puberi) 10, Herba Siegesbeckiae 10, Radix Stephaniae Tetrandrae 8, Radix Gentianae Macrophyllae 6 by following weight; Above-mentioned each crude drug is decocted with water secondary, add for the first time 6 times of weight of water, decocted 2 hours, add for the second time 4 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.17-1.19(60 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverizing adds the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 7 capsules
Take each crude drug (unit: g): Radix Angelicae Pubescentis 15, Caulis Piperis Kadsurae 15, Folium Et Cacumen Murrayae 15, Fructus Evodiae 15, Herba Taxilli 12, Caulis Spatholobi 12, Carnis Rapanae thomasianae Octopus ocellatus Gray 10, Celastrus orbiculatus Thunb. 10, Pyritum 5, Lignum Sappan 5, Rhizoma Alpiniae Officinarum 5, Caulis Lonicerae 4, Rhizoma Curcumae Longae 3 by following weight; Above-mentioned each crude drug is decocted with water secondary, add for the first time 6 times of weight of water, decocted 2 hours, add for the second time 4 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.17-1.19(60 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 8 capsules
Take each crude drug (unit: g): Radix Angelicae Pubescentis 35, Caulis Piperis Kadsurae 35, Folium Et Cacumen Murrayae 35, Fructus Evodiae 35, Herba Taxilli 30, Caulis Spatholobi 30, Carnis Rapanae thomasianae Octopus ocellatus Gray 25, Celastrus orbiculatus Thunb. 25, Pyritum 10, Lignum Sappan 12, Rhizoma Alpiniae Officinarum 12, Caulis Lonicerae 10, Rhizoma Curcumae Longae 8 by following weight; Above-mentioned each crude drug is decocted with water secondary, add for the first time 6 times of weight of water, decocted 2 hours, add for the second time 4 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.17-1.19(60 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 9 capsules
Take each crude drug (unit: g): Radix Angelicae Pubescentis 20, Caulis Piperis Kadsurae 20, Folium Et Cacumen Murrayae 20, Fructus Evodiae 20, Herba Taxilli 16, Caulis Spatholobi 16, Carnis Rapanae thomasianae Octopus ocellatus Gray 12, Celastrus orbiculatus Thunb. 12, Pyritum 7, Lignum Sappan 10, Rhizoma Alpiniae Officinarum 8, Caulis Lonicerae 7, Rhizoma Curcumae Longae 6 by following weight; Above-mentioned each crude drug is decocted with water secondary, add for the first time 6 times of weight of water, decocted 2 hours, add for the second time 4 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.17-1.19(60 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The clinical observation on the therapeutic effect test of test example 1 traditional Chinese medicine composition for treating scapulohumeral periarthritis of the present invention
One, physical data: 180 routine patients all meet the diagnostic criteria of scapulohumeral periarthritis, 25～75 years old age, average 45 years old.The patient is divided into 3 groups at random, every group of 60 examples; 3 groups of no significant differences on sex, age, the course of disease and coincident with severity degree of condition.
Two, trial drug
The medicine that embodiment of the present invention 1-9 is prepared.
Three, Therapeutic Method
180 routine patients are divided into 3 groups at random, that is: 1 group of test, test 2 groups and test 3, every group of each 60 examples, test 1 group and adopt the prepared capsule treatment of embodiment 1-3, test 2 groups and adopt the prepared capsule treatment of embodiment 4-6, test 3 groups and adopt the prepared capsule treatment of embodiment 7-9; Oral, one time 3 (0.2g crude drug/grain), 3 times on the one, 10 days is a course for the treatment of, treats altogether 4 courses for the treatment of; Period in a medicine is withdrawn other related drugs and other treatment.
Four, efficacy assessment standard
Recovery from illness: pain disappears, and it is normal that shoulder joint function recovers, on every side without tenderness and sensitive spot; Produce effects: pain basically disappears or obviously alleviates, the energy-conservation abduction of shoulder joint, after stretch 70 °; Effectively: shoulder can touch pressure pain point, the energy-conservation abduction of shoulder joint, after stretch 50 °; Invalid: the state of an illness is unchanged.
Five, clinical observation result
Clinical observation result sees Table 1.
The clinical observation on the therapeutic effect result of the test of table 1 traditional Chinese medicine composition for treating scapulohumeral periarthritis of the present invention
The clinical observation on the therapeutic effect result shows, Chinese medicine composition of the present invention has significant curative effect for the scapulohumeral periarthritis patient; Safety observe to be found, does not observe any clinical adverse, show Chinese medicine composition clinical practice of the present invention safely, have no side effect.
Claims (10)
1. the Chinese medicine composition of a cure scapulohumeral periarthritis, is characterized in that, comprises that following each component forms: Radix Angelicae Pubescentis, Caulis Piperis Kadsurae, Folium Et Cacumen Murrayae, Fructus Evodiae, Herba Taxilli, Caulis Spatholobi, Carnis Rapanae thomasianae Octopus ocellatus Gray, Celastrus orbiculatus Thunb. and Pyritum.
2. according to Chinese medicine composition claimed in claim 1, it is characterized in that, the weight portion of each component is: Radix Angelicae Pubescentis 15-35 part, Caulis Piperis Kadsurae 15-35 part, Folium Et Cacumen Murrayae 15-35 part, Fructus Evodiae 15-35 part, Herba Taxilli 12-30 part, Caulis Spatholobi 12-30 part, Carnis Rapanae thomasianae Octopus ocellatus Gray 10-25 part, Celastrus orbiculatus Thunb. 10-25 part, Pyritum 5-10 part.
3. according to Chinese medicine composition claimed in claim 2, it is characterized in that, the weight portion of each component is: Radix Angelicae Pubescentis 15-25 part, Caulis Piperis Kadsurae 15-25 part, Folium Et Cacumen Murrayae 15-25 part, Fructus Evodiae 15-25 part, Herba Taxilli 12-20 part, Caulis Spatholobi 12-20 part, Carnis Rapanae thomasianae Octopus ocellatus Gray 10-15 part, Celastrus orbiculatus Thunb. 10-15 part, Pyritum 5-8 part.
4. according to Chinese medicine composition claimed in claim 3, it is characterized in that, the weight portion of each component is: 20 parts of Radix Angelicae Pubescentiss, 20 parts of Caulis Piperis Kadsuraes, 20 parts of Folium Et Cacumen Murrayae, 20 parts of Fructus Evodiaes, 16 parts of Herba Taxillis, 16 parts of Caulis Spatholobis, 12 parts of Carnis Rapanae thomasianae Octopus ocellatus Grays, 12 parts of Celastrus orbiculatus Thunb.s, 7 parts of Pyritums.
5. the Chinese medicine composition of a cure scapulohumeral periarthritis, comprise that each component of following weight portion forms: Radix Angelicae Pubescentis 15-35 part, Caulis Piperis Kadsurae 15-35 part, Folium Et Cacumen Murrayae 15-35 part, Fructus Evodiae 15-35 part, Herba Taxilli 12-30 part, Caulis Spatholobi 12-30 part, Carnis Rapanae thomasianae Octopus ocellatus Gray 10-25 part, Celastrus orbiculatus Thunb. 10-25 part, Pyritum 5-10 part, Fructus glochidionis puberi(Herba Glochidii Puberi) 5-12 part, Herba Siegesbeckiae 5-12 part, Radix Stephaniae Tetrandrae 4-10 part, Radix Gentianae Macrophyllae 4-10 part.
6. according to Chinese medicine composition claimed in claim 1, it is characterized in that, the weight portion of each component is: 20 parts of Radix Angelicae Pubescentiss, 20 parts of Caulis Piperis Kadsuraes, 20 parts of Folium Et Cacumen Murrayae, 20 parts of Fructus Evodiaes, 16 parts of Herba Taxillis, 16 parts of Caulis Spatholobis, 12 parts of Carnis Rapanae thomasianae Octopus ocellatus Grays, 12 parts of Celastrus orbiculatus Thunb.s, 7 parts of Pyritums, Fructus glochidionis puberi(Herba Glochidii Puberi) 10 10 parts of Fen, Herba Siegesbeckiae, 8 parts of Radix Stephaniae Tetrandrae, 6 parts of Radix Gentianae Macrophyllae.
7. the Chinese medicine composition of a cure scapulohumeral periarthritis, comprise that each component of following weight portion forms: 15-35 part, Caulis Piperis Kadsurae 15-35 part, Folium Et Cacumen Murrayae 15-35 part, Fructus Evodiae 15-35 part, Herba Taxilli 12-30 part, Caulis Spatholobi 12-30 part, Carnis Rapanae thomasianae Octopus ocellatus Gray 10-25 part, Celastrus orbiculatus Thunb. 10-25 part, Pyritum 5-10 part, Lignum Sappan 5-12 part, Rhizoma Alpiniae Officinarum 5-12 part, Caulis Lonicerae 4-10 part, Rhizoma Curcumae Longae 3-8 part.
8. according to Chinese medicine composition claimed in claim 1, it is characterized in that, the weight portion of each component is: 20 parts of Radix Angelicae Pubescentiss, 20 parts of Caulis Piperis Kadsuraes, 20 parts of Folium Et Cacumen Murrayae, 20 parts of Fructus Evodiaes, 16 parts of Herba Taxillis, 16 parts of Caulis Spatholobis, 12 parts of Carnis Rapanae thomasianae Octopus ocellatus Grays, 12 parts of Celastrus orbiculatus Thunb.s, 7 parts of Pyritums, 10 parts of Lignum Sappans, 8 parts of Rhizoma Alpiniae Officinarums, 7 parts of Caulis Loniceraes, 6 parts, Rhizoma Curcumae Longae.
9. method for preparing any one described Chinese medicine composition of claim 1-8 comprises the following steps:
(1), take each crude drug by described weight proportion;
(2) each crude drug water is decocted, merge decoction liquor, filter, filtrate is condensed into clear paste, adds adjuvant or the excipient of preparations shaping, preparations shaping, and get final product.
10. the purposes of any one described Chinese medicine composition of claim 1-8 in preparation cure scapulohumeral periarthritis medicine.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1895642A (en) * | 2005-07-12 | 2007-01-17 | 侯保君 | Chinese-medicinal composition for treating neck, shoulder, waist and legs diseases and its making method |
| CN101181413A (en) * | 2007-11-21 | 2008-05-21 | 北京中科雍和医药技术有限公司 | Pharmaceutical combination for curing chronic rheumatic arthritis and scapulohumeral periarthritis as well as preparation method |
| CN102309570A (en) * | 2010-07-01 | 2012-01-11 | 王峰 | Traditional Chinese medicine (TCM) prescription for treating scapulohumeral periarthritis |
| CN102552637A (en) * | 2012-01-16 | 2012-07-11 | 金丽霞 | Chinese medicinal composition for treating scapulohumeral periarthritis and preparation method thereof |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1895642A (en) * | 2005-07-12 | 2007-01-17 | 侯保君 | Chinese-medicinal composition for treating neck, shoulder, waist and legs diseases and its making method |
| CN101181413A (en) * | 2007-11-21 | 2008-05-21 | 北京中科雍和医药技术有限公司 | Pharmaceutical combination for curing chronic rheumatic arthritis and scapulohumeral periarthritis as well as preparation method |
| CN102309570A (en) * | 2010-07-01 | 2012-01-11 | 王峰 | Traditional Chinese medicine (TCM) prescription for treating scapulohumeral periarthritis |
| CN102552637A (en) * | 2012-01-16 | 2012-07-11 | 金丽霞 | Chinese medicinal composition for treating scapulohumeral periarthritis and preparation method thereof |
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| 刘志刚: ""肩周炎的中医药治疗进展"", 《中医药信息》, no. 2, 31 December 1991 (1991-12-31), pages 17 - 21 * |
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