CN109464636A - A kind of dispelling cold and removing dampness of improvement, quack medicine of promoting blood circulation and stopping pain and its preparation method and application - Google Patents

A kind of dispelling cold and removing dampness of improvement, quack medicine of promoting blood circulation and stopping pain and its preparation method and application Download PDF

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Publication number
CN109464636A
CN109464636A CN201811224122.3A CN201811224122A CN109464636A CN 109464636 A CN109464636 A CN 109464636A CN 201811224122 A CN201811224122 A CN 201811224122A CN 109464636 A CN109464636 A CN 109464636A
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mass
radix
medicine
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张元秋
张喜万
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JINZHOU ZIJIN PHARMACEUTICAL CO Ltd
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JINZHOU ZIJIN PHARMACEUTICAL CO Ltd
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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of dispelling cold and removing dampness of improvement, quack medicine of promoting blood circulation and stopping pain and its preparation method and application, the quack medicine is prepared by the bulk pharmaceutical chemicals of following mass parts: 20-35 parts of Radix Aconiti, 15-36 parts of galangal, 20-34 parts of Cortex Cinnamomi, 18-35 parts of Radix Angelicae Sinensis, 20-40 parts of tetrandra root, 15-40 parts of Chinese ephedra, 10-25 parts of safflower, 5-20 parts of datura flower, 3-10 parts of greater celandine, 12-25 parts of Chinese prickly ash, 20-35 parts of the dried venom of toads, 10-25 parts of Semen Cleomis, 16-25 parts of lopseed, 21-38 parts of myrrh, 10-35 parts of olibanum, 5-18 parts of oil of badian, 20-30 parts of thizoma curculiginis, 3-8 parts of waxgourd peel, 30-50 parts of Radix Notoginseng, 10-20 parts of Radix Salviae Miltiorrhizae, 20-50 parts of the seed of cowherb, campanulaceae 5 - 10 parts, 15-30 parts of radix saposhnikoviae, 10-40 parts of Rhizoma Et Radix Notopterygii, 20-50 parts of the achene of Siberian cocklebur, 30-60 parts of rhizoma zingiberis, 10-20 parts of cortex cinnamomi, 30-40 parts of rhizoma corydalis, 5-10 parts of China rose, 40-60 parts of Poria cocos, 7-15 parts of caulis akebiae, 10-20 parts of mulberry leaf, 8-15 parts of dandelion, 10-30 parts of pawpaw, 15-25 parts of borneol, 8-15 parts of camphor, 2-5 parts of bagodryl hydrochloride, 3-7 parts of gaultherolin and 4-8 parts of cutaneous permeable agent.

Description

A kind of dispelling cold and removing dampness of improvement, promoting blood circulation and stopping pain quack medicine and preparation method thereof and Using
Technical field
The present invention relates to field of Chinese herbal medicine technology, more particularly to the dispelling cold and removing dampness of improvement a kind of, the dogskin of promoting blood circulation and stopping pain Plaster and its preparation method and application.
Background technique
Quack medicine is that different drugs is added according to different therapeutic purposes, and dilute thick different solid and half is made admittedly Then body is coated in skin affected part, or be first coated on cardboard, pieces of cloth and dogskin, then be attached to affected part, and this cream and the mutual of medicine are mixed It is widely used in clinic to play therapeutic effect.
Existing quack medicine formula is single, and independent action between drug, drug effect is barely satisfactory, in addition to this, due to dog Skin plaster when in use, directly in use for some time tear quack medicine with the skin contact of patient by sticky ointment When, ointment remains on the skin, is not easily cleaned clean.
Since nineteen ninety-four, long campaigns rubber ointment produces and research and development, especially to dog for Jinzhou Zijin pharmaceutcal corporation, Ltd The research and development of skin plaster have been up to more than 20 years, and the quack medicine of commercially available treatment rheumatism swelling and pain is investigated in applicant, are passed through It is linked up in many ways with hospital, pharmacy and sufferer, it is found that existing quack medicine drug effect is poor, the course for the treatment of is long, be not able to satisfy sufferer Demand, therefore dispelling cold and removing dampness, promoting blood circulation and stopping pain quack medicine are improved, by nearly research and development in 2 years, develop and a kind of newly match The quack medicine of side.
Summary of the invention
The purpose of the present invention is being formulated single problem for quack medicine existing in the prior art, and one kind is provided and is changed The quack medicine of good dispelling cold and removing dampness, promoting blood circulation and stopping pain.
It is another object of the present invention to aiming at the problem that prior art traditional Chinese medicinal ointment is not easily cleaned, and provide a kind of Goupi Gao The application of medicine is applied on the quack medicine note with cleaning layer, and cleaning layer can carry out the plaster of adherency on the skin Cleaning.
It is a further object of the invention to provide a kind of preparation methods of quack medicine, utilize unique refluxing extraction side Method sufficiently extracts important interior effective component.
The technical solution adopted to achieve the purpose of the present invention is:
The quack medicine of a kind of dispelling cold and removing dampness of improvement, promoting blood circulation and stopping pain, is prepared by the bulk pharmaceutical chemicals of following mass parts:
20-35 parts of Radix Aconiti, 15-36 parts of galangal, 20-34 parts of Cortex Cinnamomi, 18-35 parts of Radix Angelicae Sinensis, 20-40 parts of tetrandra root, Chinese ephedra 15-40 parts, 10-25 parts of safflower, 5-20 parts of datura flower, 3-10 parts of greater celandine, 12-25 parts of Chinese prickly ash, 20-35 parts of the dried venom of toads, Cauliflower 10-25 parts of seed, 16-25 parts of lopseed, 21-38 parts of myrrh, 10-35 parts of olibanum, 5-18 parts of oil of badian, 20-30 parts of thizoma curculiginis, 3-8 parts of waxgourd peel, 30-50 parts of Radix Notoginseng, 10-20 parts of Radix Salviae Miltiorrhizae, 20-50 parts of the seed of cowherb, 5-10 parts of campanulaceae, radix saposhnikoviae 15-30 parts, Qiang 10-40 parts, 20-50 parts of the achene of Siberian cocklebur, 30-60 parts of rhizoma zingiberis, 10-20 parts of cortex cinnamomi, 30-40 parts of rhizoma corydalis, 5-10 parts of China rose, Fu living 40-60 parts of Siberian cocklebur, 7-15 parts of caulis akebiae, 10-20 parts of mulberry leaf, 8-15 parts of dandelion, 10-30 parts of pawpaw, 15-25 parts of borneol, camphor 8- 15 parts, 2-5 parts of bagodryl hydrochloride, 3-7 parts of gaultherolin and 4-8 parts of cutaneous permeable agent.
In the above-mentioned technical solutions, the cutaneous permeable agent is azone.
In the above-mentioned technical solutions, the quack medicine is prepared by the bulk pharmaceutical chemicals of following mass parts:
20-30 parts of Radix Aconiti, 15-25 parts of galangal, 20-28 parts of Cortex Cinnamomi, 18-27 parts of Radix Angelicae Sinensis, 20-30 parts of tetrandra root, Chinese ephedra 15-25 parts, 10-18 parts of safflower, 5-15 parts of datura flower, 3-8 parts of greater celandine, 12-18 parts of Chinese prickly ash, 20-28 parts of the dried venom of toads, Semen Cleomis 10-17 parts, 16-20 parts of lopseed, 21-28 parts of myrrh, 10-19 parts of olibanum, 5-9 parts of oil of badian, 20-25 parts of thizoma curculiginis, winter 4-7 parts of melon skin, 35-45 parts of Radix Notoginseng, 10-15 parts of Radix Salviae Miltiorrhizae, 30-40 parts of the seed of cowherb, 5-8 parts of campanulaceae, radix saposhnikoviae 20-25 parts, Rhizoma Et Radix Notopterygii 30-35 parts, 40-50 parts of the achene of Siberian cocklebur, 50-60 parts of rhizoma zingiberis, 10-15 parts of cortex cinnamomi, 35-40 parts of rhizoma corydalis, 5-8 parts of China rose, Poria cocos 40-50 parts, 10-15 parts of caulis akebiae, 10-15 parts of mulberry leaf, 8-10 parts of dandelion, 10-15 parts of pawpaw, 15-20 parts of borneol, camphor 10- 15 parts, 2-4 parts of bagodryl hydrochloride, 3-5 parts of gaultherolin and 4-7 parts of cutaneous permeable agent.
In the above-mentioned technical solutions, the quack medicine is prepared by the bulk pharmaceutical chemicals of following mass parts:
30-35 parts of Radix Aconiti, 25-36 parts of galangal, 28-34 parts of Cortex Cinnamomi, 27-35 parts of Radix Angelicae Sinensis, 30-40 parts of tetrandra root, Chinese ephedra 25-40 parts, 18-25 parts of safflower, 15-20 parts of datura flower, 8-10 parts of greater celandine, 18-25 parts of Chinese prickly ash, 28-35 parts of the dried venom of toads, Cauliflower 17-25 parts of seed, 20-25 parts of lopseed, 28-38 parts of myrrh, 19-35 parts of olibanum, 9-18 parts of oil of badian, 25-30 parts of thizoma curculiginis, 3-4 parts of waxgourd peel, 30-35 parts of Radix Notoginseng, 15-20 parts of Radix Salviae Miltiorrhizae, 20-30 parts of the seed of cowherb, 8-10 parts of campanulaceae, radix saposhnikoviae 15-20 parts, Qiang 10-20 parts, 20-30 parts of the achene of Siberian cocklebur, 30-40 parts of rhizoma zingiberis, 15-20 parts of cortex cinnamomi, 30-35 parts of rhizoma corydalis, 8-10 parts of China rose, Fu living 50-60 parts of Siberian cocklebur, 7-10 parts of caulis akebiae, 15-20 parts of mulberry leaf, 10-15 parts of dandelion, 15-30 parts of pawpaw, 20-25 parts of borneol, camphor 8- 10 parts, 4-5 parts of bagodryl hydrochloride, 5-7 parts of gaultherolin and 7-8 parts of cutaneous permeable agent.
Another aspect of the present invention further includes application of the quack medicine in quack medicine note.
Another aspect of the present invention, further includes a kind of quack medicine note, and the quack medicine note includes that back sheet, setting exist The cleaning layer of the bonding drug effect layer of the bottom of the back sheet and the top that the back sheet is set；
The medicine film layer and light film that the bonding drug effect layer includes formation of pressure-sensitive adhesive layer, is prepared by the quack medicine, The formation of pressure-sensitive adhesive layer is bonded in the bottom of the back sheet, and the medicine film layer is coated on the bottom of the formation of pressure-sensitive adhesive layer Intermediate region and light film and the pressure-sensitive adhesive between the formation of pressure-sensitive adhesive layer and light film, around the medicine film layer Oxidant layer bonding；
The cleaning layer includes film packet and the bonding for being used to pack cleaning solution for being fixed at the top of the back sheet Cleaning towel at the top of the film packet.
In the above-mentioned technical solutions, the film packet is bag made of PVC film, is formed in the film packet clear for containing The lower surface of the cavity of washing lotion, the film packet is adhered on the upper surface of the back sheet.
In the above-mentioned technical solutions, the cleaning towel is cotton yarn towel.
In the above-mentioned technical solutions, the cleaning solution is the alcoholic solution that volumetric concentration is 30-40%.
In the above-mentioned technical solutions, the average thickness of the medicine film layer is 2-5mm.
Another aspect of the present invention, further include the dispelling cold and removing dampness of improvement a kind of, promoting blood circulation and stopping pain quack medicine preparation side Method, comprising the following steps:
20-35 mass parts Radix Aconiti, 15-36 mass parts galangal, 20-34 mass parts Cortex Cinnamomi, 18-35 mass parts are worked as Return, 20-40 mass parts tetrandra root, 15-40 mass parts Chinese ephedra, 10-25 mass parts safflower, 5-20 mass parts datura flower, 3-10 mass Part greater celandine, 12-25 mass parts Chinese prickly ash, 10-25 mass parts Semen Cleomis, 16-25 mass parts lopseed, 21-38 mass parts do not have Medicine, 20-30 mass parts thizoma curculiginis, 3-8 mass parts waxgourd peel, 30-50 mass parts Radix Notoginseng, 10-20 mass parts Radix Salviae Miltiorrhizae, 20-50 mass Part seed of cowherb, 5-10 mass parts campanulaceae, 15-30 mass parts radix saposhnikoviae, 10-40 mass parts Rhizoma Et Radix Notopterygii, the 20-50 mass parts achene of Siberian cocklebur, 30-60 mass parts rhizoma zingiberis, 10-20 mass parts cortex cinnamomi, 30-40 mass parts rhizoma corydalis, 5-10 mass parts China rose, 40-60 mass Part Poria cocos, 7-15 mass parts caulis akebiae, 10-20 mass parts mulberry leaf, 8-15 mass parts dandelion, the mixing of 10-30 mass parts pawpaw are equal After even, vibration crushing is carried out, 80 meshes is crossed, obtains mixed powder A；
Step 2, the mixed powder A is carried out refluxing extraction four times using the ethanol water that volumetric concentration is 95%, Wherein the quality of the ethanol water is 3-6 times of the mixed powder A mass, for the first time reflux 3-4 hours, second time Stream 1-2 hours flows back 30-50 minutes with the 4th time for the third time, collects filtrate, obtains medicinal extract after concentration；
Step 3, by the 20-35 mass parts dried venom of toads, 10-35 mass parts olibanum, 5-18 mass parts oil of badian, 2-5 mass Institutes are added in part bagodryl hydrochloride, 3-7 parts of gaultherolins, 4-8 parts of cutaneous permeable agents, 15-25 parts of borneols and 8-15 parts of camphors It states to be uniformly mixed in medicinal extract and obtains quack medicine.
Another aspect of the present invention further includes the application method of the quack medicine note, which is characterized in that including following Step:
Step 1, light film is torn, formation of pressure-sensitive adhesive layer is adhered to affected part, so that medicine film layer is directly contacted with affected part；
Step 2, after to drug effect, Goupi Gao drug paste is torn from skin, and by Goupi Gao drug paste doubling, pressure-sensitive adhesive The left-half and right half part of oxidant layer are bonded together；
Step 3, film is wrapped up using the object with sharp end and is broken, cleaning solution soaks cleaning towel after overflowing；
Step 4, the cleaning towel after soaking can clean up the ointment of residual on the skin.
Compared with prior art, the beneficial effects of the present invention are:
1. quack medicine of the invention makes each herbal medicine generate good association in curative effect by the reasonable compatibility of all medicines Same-action has good treatment curative effect to rheumatalgia pain.
2. quack medicine of the invention is applied to the quack medicine with cleaning layer to stick, it will can easily be adhered to skin Ointment on skin wipes, convenient to use.
3. the preparation method of quack medicine of the invention makes treatment by reasonable reflow parameters effective component extracting Imitate unique ointment.
Detailed description of the invention
Fig. 1 show the structural schematic diagram of quack medicine note of the invention.
Wherein, 1- cleaning towel, 2- film packet, 3- cleaning solution, 4- back sheet, 5- formation of pressure-sensitive adhesive layer, 6- medicine film layer, 7- light Film.
Specific embodiment
The present invention is described in further detail below in conjunction with the drawings and specific embodiments.It should be appreciated that described herein Specific embodiment be only used to explain the present invention, be not intended to limit the present invention.
Embodiment 1
The quack medicine of a kind of dispelling cold and removing dampness of improvement, promoting blood circulation and stopping pain, the quack medicine are prepared in accordance with the following methods:
Step 1, according to parts by weight, 20-35 parts of Radix Aconitis, 15-36 portions of galangals, 20-34 parts of Cortex Cinnamomis, 18-35 parts are worked as Return, 20-40 parts of tetrandra roots, 15-40 portions of Chinese ephedras, 10-25 parts of safflowers, 5-20 parts of datura flowers, 3-10 portions of greater celandines, 12-25 portions of Chinese prickly ashes, 10-25 parts of Semen Cleomis, 16-25 portions of lopseeds, 21-38 parts of myrrhs, 20-30 portions of thizoma curculiginises, 3-8 parts of waxgourd peels, 30-50 part three Seven, 10-20 parts of Radix Salviae Miltiorrhizaes, the 20-50 parts of seeds of cowherb, 5-10 parts of campanulaceaes, 15-30 portions of radix saposhnikoviaes, 10-40 portions of Rhizoma Et Radix Notopterygiis, 20-50 portions of Siberian cockleburs Son, 30-60 portions of rhizoma zingiberis, 10-20 portions of cortex cinnamomis, 30-40 parts of rhizoma corydalis, 5-10 parts of China roses, 40-60 parts of Poria cocos, 7-15 portions of caulis akebiaes, 10-20 parts of mulberry leaf, 8-15 portions of dandelions, 10-30 portions of pawpaws after mixing, then carry out vibration crushing, cross 80 meshes, are mixed Close medicinal powder A；
Step 2, the mixed powder A is carried out refluxing extraction four times using the ethanol water that volumetric concentration is 95%, Wherein the quality of the ethanol water is 3-6 times of the mixed powder A mass, for the first time reflux 3-4 hours, second time Stream 1-2 hours flows back 30-50 minutes with the 4th time for the third time, collects filtrate, obtains medicinal extract after concentration；
Step 3, by the 20-35 parts of dried venoms of toads, 10-35 parts of olibanums, 5-18 portions of oils of badian, 2-5 parts of bagodryl hydrochlorides, 3- 7 parts of gaultherolins, 4-8 parts of cutaneous permeable agents (azone), 15-25 parts of borneols and 8-15 parts of camphors are added in the medicinal extract and mix Uniformly obtain quack medicine.
Embodiment 2
A kind of quack medicine note of the dispelling cold and removing dampness of improvement, promoting blood circulation and stopping pain, including back sheet 4, be arranged in the back sheet 4 Bottom bonding drug effect layer and be arranged in the back sheet 4 top cleaning layer；
The bonding drug effect layer includes the formation of pressure-sensitive adhesive layer 5 for being bonded in the bottom of the back sheet 4, is coated on the pressure The medicine film layer 6 of the bottom intermediate region of sensitive adhesive layer 5 and the light film 7 being bonded on 5 lower surface of formation of pressure-sensitive adhesive layer；
The cleaning layer includes being fixed at the film packet 2 for being used to pack cleaning solution 3 at the top of the back sheet 4 and gluing Close the cleaning towel 1 at the top of the film packet 2；
Medical non-woven fabrics can be used in back sheet 4；
The medicine film layer 6 is prepared by the bulk pharmaceutical chemicals of following mass parts:
20 parts of Radix Aconiti, 15 parts of galangal, 20 parts of Cortex Cinnamomi, 18 parts of Radix Angelicae Sinensis, 20 parts of tetrandra root, 15 parts of Chinese ephedra, 10 parts of safflower, ocean 5 parts of golden flower, 3 parts of greater celandine, 12 parts of Chinese prickly ash, 20 parts of the dried venom of toads, 10 parts of Semen Cleomis, 16 parts of lopseed, 21 parts of myrrh, olibanum 10 Part, 20 parts of thizoma curculiginis, 3 parts of waxgourd peel, 30 parts of Radix Notoginseng, 10 parts of Radix Salviae Miltiorrhizae, 20 parts of the seed of cowherb, 5 parts of campanulaceae, is prevented 5 parts of oil of badian 15 parts of wind, 10 parts of Rhizoma Et Radix Notopterygii, 20 parts of the achene of Siberian cocklebur, 30 parts of rhizoma zingiberis, 10 parts of cortex cinnamomi, 30 parts of rhizoma corydalis, 5 parts of China rose, 40 parts of Poria cocos, wood Lead to 7 parts, 10 parts of mulberry leaf, 8 parts of dandelion, 10 parts of pawpaw, 15 parts of borneol, 8 parts of camphor, 2 parts of bagodryl hydrochloride, gaultherolin 3 parts and 4 parts of cutaneous permeable agent (azone).
The application method of the quack medicine note:
In use, light film 7 is torn, on the skin by the adherency of formation of pressure-sensitive adhesive layer 5, medicine film layer 6 directly and skin contact, Play drug effect, using a period of time, to drug effect after, Goupi Gao drug paste is torn, and by Goupi Gao drug paste doubling, pressure sensitive adhesive The left-half and right half part of adhesive layer 5 are bonded together, and using the object with sharp end, such as needle, pass through cleaning towel 1 Afterwards, film packet 2 is punctured, cleaning solution soaks cleaning towel 1 after overflowing, can be in film packet in order to improve the uniformity that cleaning towel 1 soaks Hole is uniformly pricked on 2, the cleaning towel 1 after soaking can quickly clean up the ointment of residual on the skin.
The preparation method of the medicine film layer, comprising the following steps:
Step 1, by 20 parts of Radix Aconitis, 15 portions of galangals, 20 parts of Cortex Cinnamomis, 18 parts of Radix Angelicae Sinensis, 20 parts of tetrandra roots, 15 parts of Chinese ephedras, 10 Part safflower, 5 parts of datura flowers, 3 portions of greater celandines, 12 portions of Chinese prickly ashes, 10 parts of Semen Cleomis, 16 portions of lopseeds, 21 parts of myrrhs, 20 parts of celestial beings Thatch, 3 parts of waxgourd peels, 30 portions of Radix Notoginseng, 10 parts of Radix Salviae Miltiorrhizaes, 20 parts of seeds of cowherb, 5 parts of campanulaceaes, 15 parts of radix saposhnikoviaes, 10 portions of Rhizoma Et Radix Notopterygiis, 20 parts it is grey The ears or side handles of a utensil, 30 portions of rhizoma zingiberis, 10 portions of cortex cinnamomis, 30 parts of rhizoma corydalis, 5 parts of China roses, 40 parts of Poria cocos, 7 portions of caulis akebiaes, 10 parts of mulberry leaf, 8 parts of Pu public affairs English, 10 portions of pawpaws carry out vibration crushing after mixing, in vibration mill, cross 80 meshes, obtain mixed powder A；
Step 2, the mixed powder A is carried out refluxing extraction four times using the ethanol water that volumetric concentration is 95%, Wherein the quality of the ethanol water is 3 times of the mixed powder A mass, for the first time reflux 3 hours, second of reflux 1 Hour, it flows back 30 minutes with the 4th time for the third time, collects filtrate, obtain medicinal extract after concentration；
Step 3, by 20 parts of dried venoms of toads, 15 parts of borneols, 10 parts of olibanums, 5 portions of oils of badian, 8 parts of camphors, 2 parts of hydrochloric acid benzene seas Lamine, 3 parts of gaultherolins, 5 portions of oils of badian and 4 parts of cutaneous permeable agents (azone) are added in the medicinal extract and are uniformly mixed To bulk pharmaceutical chemicals；
Step 4, the lower surface central region that the bulk pharmaceutical chemicals are coated on the formation of pressure-sensitive adhesive layer 5 is formed into medicine film layer.
The reasonable compatibility of upper all medicines, makes each herbal medicine generate good synergistic effect in curative effect, has to rheumatalgia pain Good treatment curative effect.
Embodiment 3
A kind of quack medicine note of the dispelling cold and removing dampness of improvement, promoting blood circulation and stopping pain, including back sheet 4, be arranged in the back sheet 4 Bottom bonding drug effect layer and be arranged in the back sheet 4 top cleaning layer；
The bonding drug effect layer includes the formation of pressure-sensitive adhesive layer 5 for being bonded in the bottom of the back sheet 4, is coated on the pressure The medicine film layer 6 of the bottom intermediate region of sensitive adhesive layer 5 and the light film 7 being bonded on 5 lower surface of formation of pressure-sensitive adhesive layer；
The cleaning layer includes being fixed at the film packet 2 for being used to pack cleaning solution 3 at the top of the back sheet 4 and gluing Close the cleaning towel 1 at the top of the film packet 2；
Medical non-woven fabrics can be used in back sheet 4；
The medicine film layer 6 is prepared by the bulk pharmaceutical chemicals of following mass parts:
30 parts of Radix Aconiti, 25 parts of galangal, 28 parts of Cortex Cinnamomi, 27 parts of Radix Angelicae Sinensis, 30 parts of tetrandra root, 25 parts of Chinese ephedra, 18 parts of safflower, ocean 15 parts of golden flower, 8 parts of greater celandine, 18 parts of Chinese prickly ash, 28 parts of the dried venom of toads, 17 parts of Semen Cleomis, 20 parts of lopseed, 28 parts of myrrh, olibanum 19 Part, 9 parts of oil of badian, 30 parts of thizoma curculiginis, 8 parts of waxgourd peel, 50 parts of Radix Notoginseng, 20 parts of Radix Salviae Miltiorrhizae, 50 parts of the seed of cowherb, 10 parts of campanulaceae, Windproof 30 parts, 40 parts of Rhizoma Et Radix Notopterygii, 50 parts of the achene of Siberian cocklebur, 60 parts of rhizoma zingiberis, 20 parts of cortex cinnamomi, 40 parts of rhizoma corydalis, 10 parts of China rose, Poria cocos 60 Part, 15 parts of caulis akebiae, 20 parts of mulberry leaf, 15 parts of dandelion, 30 parts of pawpaw, 25 parts of borneol, 15 parts of camphor, 5 parts of bagodryl hydrochloride, water 7 parts of poplar acid methyl esters and 8 parts of cutaneous permeable agent (azone).
The application method of the quack medicine note:
In use, light film 7 is torn, on the skin by the adherency of formation of pressure-sensitive adhesive layer 5, medicine film layer 6 directly and skin contact, It plays drug effect Goupi Gao drug paste is torn in use for some time, and by Goupi Gao drug paste doubling, formation of pressure-sensitive adhesive layer 5 Left-half and right half part are bonded together, using the object with sharp end, such as needle, after passing through cleaning towel 1, by film packet 2 puncture, and cleaning solution soaks cleaning towel 1 after overflowing, and in order to improve the uniformity that cleaning towel 1 soaks, can uniformly prick on film packet 2 Hole, the cleaning towel 1 after soaking can quickly clean up the ointment of residual on the skin.
The preparation method of the medicine film layer, comprising the following steps:
Step 1, by 30 parts of Radix Aconitis, 25 portions of galangals, 28 parts of Cortex Cinnamomis, 27 parts of Radix Angelicae Sinensis, 30 parts of tetrandra roots, 25 parts of Chinese ephedras, 18 Part safflower, 15 parts of datura flowers, 8 portions of greater celandines, 18 portions of Chinese prickly ashes, 17 parts of Semen Cleomis, 20 portions of lopseeds, 28 parts of myrrhs, 19 parts of creams Perfume, 9 portions of oils of badian, 30 portions of thizoma curculiginises, 8 parts of waxgourd peels, 50 portions of Radix Notoginseng, 20 parts of Radix Salviae Miltiorrhizaes, 50 parts of seeds of cowherb, 10 parts of campanulaceaes, 30 parts of radix saposhnikoviaes, 40 portions of Rhizoma Et Radix Notopterygiis, 50 portions of achenes of Siberian cocklebur, 60 portions of rhizoma zingiberis, 20 portions of cortex cinnamomis, 40 parts of rhizoma corydalis, 10 parts of China roses, 60 parts of Fu Siberian cocklebur, 15 portions of caulis akebiaes, 20 parts of mulberry leaf, 15 portions of dandelions, 30 portions of pawpaws carry out vibration powder after mixing, in vibration mill It is broken, 80 meshes are crossed, mixed powder A is obtained；
Step 2, the mixed powder A is carried out refluxing extraction four times using the ethanol water that volumetric concentration is 95%, Wherein the quality of the ethanol water is 6 times of the mixed powder A mass, for the first time reflux 4 hours, second of reflux 2 Hour, it flows back 50 minutes with the 4th time for the third time, collects filtrate, obtain medicinal extract after concentration；
Step 3, by 28 parts of dried venoms of toads, 19 parts of olibanum, 9 parts, 5 parts bagodryl hydrochlorides of oil of badian, 7 parts of salicylic acid first Ester, 8 parts of cutaneous permeable agents (azone), 25 parts of borneols and 15 parts of camphors, which are added to be uniformly mixed in the medicinal extract, obtains bulk pharmaceutical chemicals；
Step 4, the lower surface central region that the bulk pharmaceutical chemicals are coated on the formation of pressure-sensitive adhesive layer 5 is formed into medicine film layer.
The reasonable compatibility of upper all medicines, makes each herbal medicine generate good synergistic effect in curative effect, has to rheumatalgia pain Good treatment curative effect.
Embodiment 4
A kind of quack medicine note of the dispelling cold and removing dampness of improvement, promoting blood circulation and stopping pain, including back sheet 4, be arranged in the back sheet 4 Bottom bonding drug effect layer and be arranged in the back sheet 4 top cleaning layer；
The bonding drug effect layer includes the formation of pressure-sensitive adhesive layer 5 for being bonded in the bottom of the back sheet 4, is coated on the pressure The medicine film layer 6 of the bottom intermediate region of sensitive adhesive layer 5 and the light film 7 being bonded on 5 lower surface of formation of pressure-sensitive adhesive layer；
The cleaning layer includes being fixed at the film packet 2 for being used to pack cleaning solution 3 at the top of the back sheet 4 and gluing Close the cleaning towel 1 at the top of the film packet 2；
Medical non-woven fabrics can be used in back sheet 4；
The medicine film layer 6 is prepared by the bulk pharmaceutical chemicals of following mass parts:
35 parts of Radix Aconiti, 36 parts of galangal, 34 parts of Cortex Cinnamomi, 35 parts of Radix Angelicae Sinensis, 40 parts of tetrandra root, 40 parts of Chinese ephedra, 25 parts of safflower, ocean 20 parts of golden flower, 10 parts of greater celandine, 25 parts of Chinese prickly ash, 35 parts of the dried venom of toads, 25 parts of Semen Cleomis, 25 parts of lopseed, 38 parts of myrrh, olibanum 35 Part, 18 parts of oil of badian, 25 parts of thizoma curculiginis, 7 parts of waxgourd peel, 45 parts of Radix Notoginseng, 15 parts of Radix Salviae Miltiorrhizae, 40 parts of the seed of cowherb, 8 parts of campanulaceae, Radix saposhnikoviae 25 parts, 35 parts of Rhizoma Et Radix Notopterygii, 40 parts of the achene of Siberian cocklebur, 50 parts of rhizoma zingiberis, 15 parts of cortex cinnamomi, 40 parts of rhizoma corydalis, 8 parts of China rose, 50 parts of Poria cocos, 10 parts of caulis akebiae, 15 parts of mulberry leaf, 10 parts of dandelion, 15 parts of pawpaw, 20 parts of borneol, 10 parts of camphor, 4 parts of bagodryl hydrochloride, bigcatkin willow 5 parts of sour methyl esters and 7 parts of cutaneous permeable agent (azone)；
The application method of the quack medicine note:
In use, light film 7 is torn, on the skin by the adherency of formation of pressure-sensitive adhesive layer 5, medicine film layer 6 directly and skin contact, It plays drug effect Goupi Gao drug paste is torn in use for some time, and by Goupi Gao drug paste doubling, formation of pressure-sensitive adhesive layer 5 Left-half and right half part are bonded together, using the object with sharp end, such as needle, after passing through cleaning towel 1, by film packet 2 puncture, and cleaning solution soaks cleaning towel 1 after overflowing, and in order to improve the uniformity that cleaning towel 1 soaks, can uniformly prick on film packet 2 Hole, the cleaning towel 1 after soaking can quickly clean up the ointment of residual on the skin.
The preparation method of the medicine film layer, comprising the following steps:
Step 1, by 35 parts of Radix Aconitis, 36 portions of galangals, 34 parts of Cortex Cinnamomis, 35 parts of Radix Angelicae Sinensis, 40 parts of tetrandra roots, 40 parts of Chinese ephedras, 25 Part safflower, 20 parts of datura flowers, 10 portions of greater celandines, 25 portions of Chinese prickly ashes, 35 parts of dried venoms of toads, 25 parts of Semen Cleomis, 25 portions of lopseeds, 38 parts do not have Medicine, 35 parts of olibanums, 18 portions of oils of badian, 25 portions of thizoma curculiginises, 7 parts of waxgourd peels, 45 portions of Radix Notoginseng, 15 parts of Radix Salviae Miltiorrhizaes, 40 parts of seeds of cowherb, 8 parts of campanulaceaes, 25 parts of radix saposhnikoviaes, 35 portions of Rhizoma Et Radix Notopterygiis, 40 portions of achenes of Siberian cocklebur, 50 portions of rhizoma zingiberis, 15 portions of cortex cinnamomis, 40 parts of rhizoma corydalis, 8 parts of China roses, 50 parts of Poria cocos, 10 portions of caulis akebiaes, 15 parts of mulberry leaf, 10 portions of dandelions, 15 portions of pawpaws after mixing, shake in vibration mill It is dynamic to crush, 80 meshes are crossed, mixed powder A is obtained；
Step 2, the mixed powder A is carried out refluxing extraction four times using the ethanol water that volumetric concentration is 95%, Wherein the quality of the ethanol water is 5 times of the mixed powder A mass, for the first time reflux 3.5 hours, second of reflux It 1.5 hours, flows back 40 minutes with the 4th time for the third time, collects filtrate, obtain medicinal extract after concentration；
Step 3, by 28 parts of dried venoms of toads, 35 parts of olibanums, 18 portions of oils of badian, 20 parts of borneols, 10 parts of camphors, 4 parts of hydrochloric acid benzene Extra large Lamine, 5 parts of gaultherolins and 7 parts of cutaneous permeable agents (azone), which are added to be uniformly mixed in the medicinal extract, obtains bulk pharmaceutical chemicals；
Step 4, the lower surface central region that the bulk pharmaceutical chemicals are coated on the formation of pressure-sensitive adhesive layer 5 is formed into medicine film layer.
The reasonable compatibility of upper all medicines, makes each herbal medicine generate good synergistic effect in curative effect, has to rheumatalgia pain Good treatment curative effect.
Embodiment 5
The present embodiment improves the structure of quack medicine note on the basis of embodiment 1 or 2 or 3, and the film packet 2 is Bag made of PVC film is formed with the cavity for containing cleaning solution in the film packet 2, and the lower surface of the film packet 2 is adhered to On the upper surface of the back sheet 4.
It is preferred that the cleaning towel 1 is cotton yarn towel.
It is preferred that the cleaning solution is the alcoholic solution that volumetric concentration is 30-40%.
Embodiment 6
The present embodiment is verified in the drug effect of the quack medicine note to the embodiment of the present invention 3.
Case 1, male, 38 years old, patient's shoulder pain, especially in the rainy day, arm can not be lifted normally, dare not be exerted oneself, and be used After medicine three days, arm can be lifted up, and feeling of pain slows down, after medication ten days, arm can normal activity, feeling of pain disappear.Mulberry leaf, Dandelion and caulis akebiae compatibility play good exsiccation, improve curative effect.
Case 2, female, 73 years old, which needed slowly to stand after squatting down, after medication three days, feeling of pain Slow down, after medication ten days, feeling of pain disappears, can normal stand after squatting down.Rhizoma corydalis, pawpaw mutual compatibility, play analgesic Function, effect is obvious.
Case 3, male, 35 years old, the patient in sitting is incorrect to lead to neck and shoulder pain, poor sleeping quality, after medication three days, pain Sense slows down, and sleep is improved, and after medication ten days, feeling of pain disappears.
Case 4, female, 80 years old, the patient's waist pain, especially in wet environment, waist can not exert oneself, can not straight waist row It walks, after medication five days, flank pain sense weakens, can straight waist walking after medication 15 days.Caulis akebiae, rhizoma zingiberis and the seed of cowherb are mutual Compatibility has the effect of apparent damp dispelling and pain relieving.
Case 5, male, 48 years old, the patient was in rainy day flank pain, and fine day is without abnormal, after medication ten days, rainy day waist without Feeling of pain.
Case 6, female, 45 years old, which was not available cold water laundry wash vegetables, after use, shoulder pain, and medication 15 days Afterwards, then with cold water, shoulder is painless.
Case 7, male, 39 years old, knee pain pain was obvious in winter by the patient, painless in temperature higher summer, After summer medication 20 days, when winter approached, knee is painless again.
Case 8, female, 56 years old, when which exerts oneself, wrist pain can not do heavier housework, and medication five days When, feeling of pain weakens, and after medication 15 days, can normally do housework.Radix saposhnikoviae, China rose and Rhizoma Et Radix Notopterygii compatibility, can promote microcirculation, rise To the effect of analgesic.
Case 9, male, 78 years old, the long-term Low Back Pain of the patient can not keep sitting posture for a long time, after medication ten days, flank pain sense Weaken, after medication 20 days, sitting posture can be kept for a long time, feeling of pain disappears.The seed of cowherb, campanulaceae and pawpaw compatibility have and live The curative effect of blood and relieving pain.
Case 10, female, 53 years old, after which does housework for a long time, shoulder pain sense was obvious, can be normal after medication five days It does housework, at medication ten days, then it is painless.
Drug effect verifying is carried out to the quack medicine note of other embodiments of the invention, it may have the medicine of case 1-10 described above Effect.
The above is only a preferred embodiment of the present invention, it is noted that for the common skill of the art For art personnel, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications Also it should be regarded as protection scope of the present invention.

Claims (10)

1. the quack medicine of a kind of dispelling cold and removing dampness of improvement, promoting blood circulation and stopping pain, which is characterized in that the quack medicine is by following quality The bulk pharmaceutical chemicals of part are prepared:
20-35 parts of Radix Aconiti, 15-36 parts of galangal, 20-34 parts of Cortex Cinnamomi, 18-35 parts of Radix Angelicae Sinensis, 20-40 parts of tetrandra root, Chinese ephedra 15-40 Part, 10-25 parts of safflower, 5-20 parts of datura flower, 3-10 parts of greater celandine, 12-25 parts of Chinese prickly ash, 20-35 parts of the dried venom of toads, Semen Cleomis 10- 25 parts, 16-25 parts of lopseed, 21-38 parts of myrrh, 10-35 parts of olibanum, 5-18 parts of oil of badian, 20-30 parts of thizoma curculiginis, wax gourd 3-8 parts of skin, 30-50 parts of Radix Notoginseng, 10-20 parts of Radix Salviae Miltiorrhizae, 20-50 parts of the seed of cowherb, 5-10 parts of campanulaceae, radix saposhnikoviae 15-30 parts, Rhizoma Et Radix Notopterygii 10-40 parts, 20-50 parts of the achene of Siberian cocklebur, 30-60 parts of rhizoma zingiberis, 10-20 parts of cortex cinnamomi, 30-40 parts of rhizoma corydalis, 5-10 parts of China rose, Poria cocos 40-60 parts, 7-15 parts of caulis akebiae, 10-20 parts of mulberry leaf, 8-15 parts of dandelion, 10-30 parts of pawpaw, 15-25 parts of borneol, camphor 8-15 Part, 2-5 parts of bagodryl hydrochloride, 3-7 parts of gaultherolin and 4-8 parts of cutaneous permeable agent.
2. quack medicine as described in claim 1, which is characterized in that the quack medicine by following mass parts bulk pharmaceutical chemicals system It is standby to form:
20-30 parts of Radix Aconiti, 15-25 parts of galangal, 20-28 parts of Cortex Cinnamomi, 18-27 parts of Radix Angelicae Sinensis, 20-30 parts of tetrandra root, Chinese ephedra 15-25 Part, 10-18 parts of safflower, 5-15 parts of datura flower, 3-8 parts of greater celandine, 12-18 parts of Chinese prickly ash, 20-28 parts of the dried venom of toads, Semen Cleomis 10-17 Part, 16-20 parts of lopseed, 21-28 parts of myrrh, 10-19 parts of olibanum, 5-9 parts of oil of badian, 20-25 parts of thizoma curculiginis, waxgourd peel 4- 7 parts, 35-45 parts of Radix Notoginseng, 10-15 parts of Radix Salviae Miltiorrhizae, 30-40 parts of the seed of cowherb, 5-8 parts of campanulaceae, 20-25 parts of radix saposhnikoviae, Rhizoma Et Radix Notopterygii 30-35 Part, 40-50 parts of the achene of Siberian cocklebur, 50-60 parts of rhizoma zingiberis, 10-15 parts of cortex cinnamomi, 35-40 parts of rhizoma corydalis, 5-8 parts of China rose, Poria cocos 40-50 Part, 10-15 parts of caulis akebiae, 10-15 parts of mulberry leaf, 8-10 parts of dandelion, 10-15 parts of pawpaw, 15-20 parts of borneol, 10-15 parts of camphor, 2-4 parts of bagodryl hydrochloride, 3-5 parts of gaultherolin and 4-7 parts of cutaneous permeable agent.
3. quack medicine as described in claim 1, which is characterized in that the quack medicine by following mass parts bulk pharmaceutical chemicals system It is standby to form:
30-35 parts of Radix Aconiti, 25-36 parts of galangal, 28-34 parts of Cortex Cinnamomi, 27-35 parts of Radix Angelicae Sinensis, 30-40 parts of tetrandra root, Chinese ephedra 25-40 Part, 18-25 parts of safflower, 15-20 parts of datura flower, 8-10 parts of greater celandine, 18-25 parts of Chinese prickly ash, 28-35 parts of the dried venom of toads, Semen Cleomis 17- 25 parts, 20-25 parts of lopseed, 28-38 parts of myrrh, 19-35 parts of olibanum, 9-18 parts of oil of badian, 25-30 parts of thizoma curculiginis, wax gourd 3-4 parts of skin, 30-35 parts of Radix Notoginseng, 15-20 parts of Radix Salviae Miltiorrhizae, 20-30 parts of the seed of cowherb, 8-10 parts of campanulaceae, radix saposhnikoviae 15-20 parts, Rhizoma Et Radix Notopterygii 10-20 parts, 20-30 parts of the achene of Siberian cocklebur, 30-40 parts of rhizoma zingiberis, 15-20 parts of cortex cinnamomi, 30-35 parts of rhizoma corydalis, 8-10 parts of China rose, Poria cocos 50-60 parts, 7-10 parts of caulis akebiae, 15-20 parts of mulberry leaf, 10-15 parts of dandelion, 15-30 parts of pawpaw, 20-25 parts of borneol, camphor 8-10 Part, 4-5 parts of bagodryl hydrochloride, 5-7 parts of gaultherolin and 7-8 parts of cutaneous permeable agent.
4. application of the quack medicine as claimed in any one of claims 1-3 in Goupi Gao drug paste.
5. a kind of quack medicine note, which is characterized in that the quack medicine note includes back sheet (4), is arranged in the back sheet (4) cleaning layer of the bonding drug effect layer of bottom with setting at the top of the back sheet (4)；
The medicine film layer that the bonding drug effect layer includes formation of pressure-sensitive adhesive layer (5), is prepared by quack medicine described in claim 1 (6) and light film (7), the formation of pressure-sensitive adhesive layer (5) are bonded in the bottom of the back sheet (4), and the medicine film layer (6) is coated on The bottom intermediate region of the formation of pressure-sensitive adhesive layer (5) and between the formation of pressure-sensitive adhesive layer (5) and light film (7), it is described Light film (7) and the formation of pressure-sensitive adhesive layer (5) around medicine film layer (6) bond；
The cleaning layer include be fixed at the back sheet (4) top for pack cleaning solution (3) film packet (2) and It is bonded in the cleaning towel (1) at the top of the film packet (2).
6. quack medicine note as claimed in claim 4, which is characterized in that the film packet (2) is bag made of PVC film, institute The cavity being formed in film packet (2) for containing cleaning solution (3) is stated, the lower surface of the film packet (2) is adhered to the back sheet (4) on upper surface.
7. quack medicine note as claimed in claim 4, which is characterized in that the cleaning towel (1) is cotton yarn towel.
8. quack medicine note as claimed in claim 4, which is characterized in that it is 30-40% that the cleaning solution (3), which is volumetric concentration, Alcoholic solution.
9. a kind of preparation method of the quack medicine of dispelling cold and removing dampness of improvement, promoting blood circulation and stopping pain, comprising the following steps:
Step 1,20-35 mass parts Radix Aconiti, 15-36 mass parts galangal, 20-34 mass parts Cortex Cinnamomi, 18-35 mass parts are worked as Return, 20-40 mass parts tetrandra root, 15-40 mass parts Chinese ephedra, 10-25 mass parts safflower, 5-20 mass parts datura flower, 3-10 mass Part greater celandine, 12-25 mass parts Chinese prickly ash, 10-25 mass parts Semen Cleomis, 16-25 mass parts lopseed, 21-38 mass parts do not have Medicine, 20-30 mass parts thizoma curculiginis, 3-8 mass parts waxgourd peel, 30-50 mass parts Radix Notoginseng, 10-20 mass parts Radix Salviae Miltiorrhizae, 20-50 mass Part seed of cowherb, 5-10 mass parts campanulaceae, 15-30 mass parts radix saposhnikoviae, 10-40 mass parts Rhizoma Et Radix Notopterygii, the 20-50 mass parts achene of Siberian cocklebur, 30-60 mass parts rhizoma zingiberis, 10-20 mass parts cortex cinnamomi, 30-40 mass parts rhizoma corydalis, 5-10 mass parts China rose, 40-60 mass Part Poria cocos, 7-15 mass parts caulis akebiae, 10-20 mass parts mulberry leaf, 8-15 mass parts dandelion, the mixing of 10-30 mass parts pawpaw are equal After even, vibration crushing is carried out, 80 meshes is crossed, obtains mixed powder A；
Step 2, the mixed powder A is carried out refluxing extraction four times using the ethanol water that volumetric concentration is 95%, wherein The quality of the ethanol water is 3-6 times of the mixed powder A mass, for the first time reflux 3-4 hours, second of 1- that flows back It 2 hours, flows back 30-50 minutes with the 4th time for the third time, collects filtrate, obtain medicinal extract after concentration；
Step 3, by the 20-35 mass parts dried venom of toads, 10-35 mass parts olibanum, 5-18 mass parts oil of badian, 2-5 mass parts salt The leaching is added in sour diphenhydramine, 3-7 part gaultherolin, 4-8 parts of cutaneous permeable agents, 15-25 parts of borneols and 8-15 parts of camphors It is uniformly mixed in cream and obtains quack medicine.
10. the application method of quack medicine note as claimed in claim 9, which comprises the following steps:
Step 1, light film (7) is torn, formation of pressure-sensitive adhesive layer (5) is adhered to affected part, so that medicine film layer (6) directly connects with affected part Touching；
Step 2, Goupi Gao drug paste is torn from skin, and by Goupi Gao drug paste doubling, the left side of formation of pressure-sensitive adhesive layer (5) Divide and right half part is bonded together；
Step 3, film packet (2) is punctured using the object with sharp end, cleaning solution (3) soaks cleaning towel (1) after overflowing；
Step 4, the cleaning towel (1) after soaking can clean up the ointment of residual on the skin.
CN201811224122.3A 2018-10-19 2018-10-19 A kind of dispelling cold and removing dampness of improvement, quack medicine of promoting blood circulation and stopping pain and its preparation method and application Pending CN109464636A (en)

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Publication number Priority date Publication date Assignee Title
CN110354105A (en) * 2019-08-21 2019-10-22 江苏博润医疗集团有限公司 It is a kind of for treating the plaster of rheumatism

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CN104984209A (en) * 2015-08-10 2015-10-21 锦州紫金药业有限公司 Improved dog skin plaster treating acute sprain and bruise, rheumatism and pain and preparing method of improved dog skin plaster
WO2017220052A2 (en) * 2016-06-21 2017-12-28 赵吉永 Formulation treating rheumatoid bone pain
CN108514554A (en) * 2018-06-13 2018-09-11 无锡市中医医院 A kind of Chinese medicine detumescence patch

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Publication number Priority date Publication date Assignee Title
CN201658672U (en) * 2010-04-13 2010-12-01 锦州紫金药业有限公司 Improved dogskin plaster
CN104984209A (en) * 2015-08-10 2015-10-21 锦州紫金药业有限公司 Improved dog skin plaster treating acute sprain and bruise, rheumatism and pain and preparing method of improved dog skin plaster
WO2017220052A2 (en) * 2016-06-21 2017-12-28 赵吉永 Formulation treating rheumatoid bone pain
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Application publication date: 20190315