CN108096095A - A kind of composite whitening and composition and its application for soothing the skin stimulatory function - Google Patents
A kind of composite whitening and composition and its application for soothing the skin stimulatory function Download PDFInfo
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- CN108096095A CN108096095A CN201711450619.2A CN201711450619A CN108096095A CN 108096095 A CN108096095 A CN 108096095A CN 201711450619 A CN201711450619 A CN 201711450619A CN 108096095 A CN108096095 A CN 108096095A
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- Prior art keywords
- skin
- composition
- whitening
- stimulatory function
- soothing
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Abstract
The present invention discloses a kind of composite whitening and soothes the skin the composition of stimulatory function, including following components in percentage by weight：Symwhite-337 0.01~1.0%, licoflavone 0.01~5%, Baical Skullcap root P.E 0.01~10%, licorice 0.01~10%, Gotu Kola P.E 0.01~10%, german chamomile extract 0.01~10%, polyalcohol 1~10%, surplus are water.The present invention is by the way that by the whitening agent of specific plant whitening ingredient, chemical synthesis and compound with the ingredient for soothing the skin stimulation, as whitening composition for cosmetics, which has apparent white-skinned face function to skin, does not stimulate skin；The composition of the present invention is used to prepare skin-lightening cosmetic, few with usage amount, whitening effect is good, to the inirritative advantage of skin.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of composite whitening and the combination for soothing the skin stimulatory function
Object and its application.
Background technology
With the improvement of living standards, people increasingly pay close attention to skin nursing (the especially nursing of skin of face).Its
In, the demand of skin whitening nursing occupies Asian to skin care needs focus of attention position always.Consumer is to whitening
The expectation of skin-protection product is mainly mild, whitening is comprehensive and has good effect, and skin is not stimulated after use.Existing whitening
The whitening composition that the skin care item species of function is various but used is mostly the single compound synthesized, and shortcoming is that function is more single,
Exclusive use is difficult to meet the needs of consumer is to white-skinned face function.The whitening composition of plant origin is there is also deficiency, in low concentration
It is difficult to reach consumer's desired remarkable result during use, skin irritatin or sense of discomfort can be caused again by increasing usage amount.
Existing whitening technical solution, as CN201610161116 employ whitening agent is wrapped up after the technical side that uses
Case, but whitening agent stability in use can only be solved, do not solve the problems, such as stimulation of the whitening agent to skin.
Whitenings and releive ingredient of the CN201410018343 and CN201410019217 all using Chinese medicine source, these whitening compositions
In low concentration in use, whitening effect is not so good as the whitening agent of chemical synthesis.
It is non-stimulated to skin therefore, it is necessary to a kind of mild, combine the whitening composition of chemical whitening agent and plant origin
Lightening compositions.
The content of the invention
In view of the problems of the existing technology, there is composite whitening and releive the object of the present invention is to provide a kind of
Composition, by by the whitening agent of specific plant whitening ingredient, chemical synthesis and with soothe the skin stimulation into
It is point compound, as whitening composition for cosmetics, while realizing skin-whitening, it the senses of discomfort such as will not cause to stimulate to skin.
The technical solution adopted by the present invention is：A kind of composite whitening and the composition for soothing the skin stimulatory function, including with
The component of lower weight percent：Symwhite-337 0.01~1.0%, licoflavone 0.01~5%, Baical Skullcap root P.E 0.01
~10%, licorice 0.01~10%, Gotu Kola P.E 0.01~10%, german chamomile extract 0.01~10% is polynary
Alcohol 1~10%, surplus are water.
Preferably, composite whitening and the composition for soothing the skin stimulatory function, including following components in percentage by weight：Benzene
Ethyl resorcinol 0.03~0.08%, licoflavone 1~5%, Baical Skullcap root P.E 1~8%, licorice 0.5~8%,
Gotu Kola P.E 0.5~6%, german chamomile extract 0.1~8%, polyalcohol 2~8%, surplus are water.
Preferably, composite whitening and the composition for soothing the skin stimulatory function, including following components in percentage by weight：Benzene
Ethyl resorcinol 0.03~0.06%, licoflavone 1~4%, Baical Skullcap root P.E 2~8%, licorice 1~6%, product
The careless extract 1~5% of snow, german chamomile extract 0.5~5%, polyalcohol 3~6%, surplus is water.
Preferably, the polyalcohol is propylene glycol or butanediol.
The present invention also provides the preparation method of composite whitening He the composition for soothing the skin stimulatory function, including following step
Suddenly：
(1) licoflavone, Baical Skullcap root P.E, licorice, Gotu Kola P.E, german chamomile extraction are sequentially added in water
Object stirs evenly, and obtains mixed solution；
(2) Symwhite-337 is dispersed in polyalcohol, is slow added into the mixed solution obtained in step 1)
In, it stirs evenly, you can obtain composite whitening and soothe the skin the composition of stimulatory function.
The present invention also provides a kind of skin preparations for extenal use, the skin preparations for extenal use includes composite whitening and soothes the skin stimulation
The composition of function, wherein percentage, composite whitening account for external preparation for skin with the composition for soothing the skin stimulatory function
The 1%~50% of agent total weight.
Preferably, the dosage form of the skin preparations for extenal use is solution, gel, lotion or cream shape.
The present invention also provides the preparation methods of the skin preparations for extenal use, comprise the following steps：
1) composite whitening with the composition for soothing the skin stimulatory function is added to the water and be uniformly dissolved；
2) acceptable auxiliary material pharmaceutically or on cosmetics is added in, is uniformly mixed, you can obtain the skin preparations for extenal use.
The present invention also provides composite whitening and the composition of stimulatory function is soothed the skin as whitening active ingredients and easypro
Slow application of the skin irritatin active ingredient in cosmetics.It can be by the composite whitening and the composition for soothing the skin stimulatory function
The effect of making an addition in cosmetics, assigning cosmetics whitening and soothe the skin stimulation.
The beneficial effects of the invention are as follows：The present invention by by the whitening agent of specific plant whitening ingredient, chemical synthesis with
And it is compound with the ingredient for soothing the skin stimulation, as whitening composition for cosmetics, which has skin bright
Aobvious white-skinned face function, does not stimulate skin；The composition of the present invention is used to prepare skin-lightening cosmetic, whitening few with usage amount
Effect is good, to the inirritative advantage of skin.
Specific embodiment
Below by way of specific embodiment come the present invention is further illustrated, but these embodiments simply to illustrate that,
It is not limitation of the present invention.
1 composite whitening of embodiment and soothe the skin stimulatory function composition A preparation
0.01g licoflavones, 10g Baical Skullcap root P.Es, 10g licorices, 10g accumulated snow are sequentially added in 58.98g water
Careless extract, 10g german chamomile extracts, is uniformly mixing to obtain mixed solution 98.99g；
0.01g Symwhite-337s are first dispersed in 1g polyalcohols, is slow added into above-mentioned mixed solution, stirs
It mixes uniformly to get composite whitening and the composition A for soothing the skin stimulatory function.
2 composite whitening of embodiment and soothe the skin stimulatory function composition B preparation
Sequentially add 5g licoflavones in 80g water, 1g Baical Skullcap root P.Es, 1g licorices, 1g Gotu Kola P.Es,
1g german chamomile extracts, are uniformly mixing to obtain mixed solution 89g；
1g Symwhite-337s are first dispersed in 10g polyalcohols, are slow added into above-mentioned mixed solution, are stirred
Uniformly to get composite whitening and the composition B for soothing the skin stimulatory function.
3 composite whitening of embodiment and soothe the skin stimulatory function composition C preparation
1g licoflavones, 0.01g Baical Skullcap root P.Es, 0.01g licorices, 0.01g are sequentially added in 93.86g water
Gotu Kola P.E, 0.01g german chamomile extracts, is uniformly mixing to obtain mixed solution 94.9g.
0.1g Symwhite-337s are first dispersed in 5g polyalcohols, is slow added into above-mentioned mixed solution, stirs
It mixes uniformly to get composite whitening and the composition C for soothing the skin stimulatory function.
4 whitening of embodiment is releived the preparation of face cream
Table 1 gives the composite whitening containing the present invention and soothes the skin the prescription for skin cream of the composition of stimulatory function,
The dosage of each substance is represented with mass percent.
1 whitening of table is releived prescription for skin cream
Preparation method：The dissolving of 80 DEG C of A phases is uniformly mixed, and the 80 DEG C of dissolvings of B phases are uniformly mixed, and A is added to B phases and equal during emulsification
Matter 5 minutes adds in C phases and D phases and stirs 5 minutes when being cooled to 45 DEG C, you can.
5 whitening of embodiment is releived the preparation of facial treatment milk
Table 2 provides the composite whitening containing the present invention and soothes the skin the facial treatment milk formula of the composition of stimulatory function,
The dosage of each substance is represented with mass percent.
2 whitening of table is releived facial treatment milk formula
Preparation method：The dissolving of 80 DEG C of A phases is uniformly mixed, and the 80 DEG C of dissolvings of B phases are uniformly mixed, and A is added to B phases and equal during emulsification
Matter 5 minutes adds in C phases and D phases and stirs 5 minutes when being cooled to 45 DEG C, you can.
6 whitening of embodiment is releived the preparation of facial treatment essence
Table 3 provides the composite whitening containing the present invention and soothes the skin the facial treatment essence formula of the composition of stimulatory function,
The dosage of each substance is represented with mass percent.
3 whitening of table is releived facial treatment essence formula
Preparation method：The dissolving of 80 DEG C of A phases is uniformly mixed, and B phases and C phases are added in when being cooled to 45 DEG C and stirs 5 minutes, i.e.,
It can.
7 composition whitening active of embodiment is tested
It is completely molten respectively by composite whitening prepared by Examples 1 to 3 and composition A, B and C for soothing the skin stimulatory function
In deionized water, 1g/L testing sample solutions are configured to, for measuring tyrosinase inhibitory activity, using ursin as control whitening
Agent.Determination step is：(tyrosine is dissolved in pH6.8 dipotassium hydrogen phosphates-potassium dihydrogen phosphate and delays 3.75mL 1.8mM tyrosine solutions
Rush in solution), sample solution 2mL be uniformly mixed, 35 DEG C of constant temperature, add in 0.25mL tyrosinase solutions (500U/g), 35 DEG C of perseverances
After temperature reaction 10min, tyrosinase activity 503nhibiting concentration IC is measured50.Suction is equally measured as blank solution by the use of deionized water
Luminosity.Acquired results are as shown in table 4.
4 composition of table is to the inhibitory action of tyrosinase
The result of the test of table 4 shows composite whitening of the invention and soothes the skin the IC of the composition of stimulatory function50Value is remote
Much smaller than the IC of ursin50Value, the composite whitening for illustrating the present invention and the composition for soothing the skin stimulatory function can effectively press down
Tyrosinase activity processed, and function is superior to currently used whitening agent ursin.
8 product whitening of embodiment is releived efficacy test
Whitening will be prepared according to embodiment 5 and releives facial treatment milk as sample, while water consumption substitution composite whitening therein
With the composition B component for soothing the skin stimulatory function, other compositions are identical to prepare placebo.Using double blinding, opening, it is random, from
Body cross-reference observational study.Screening close symbol test condition 20 volunteers (male 8 people, 12 people of female, the age 25 years old to 40 years old it
Between, average age 29.14 ± 2.48 years old).Test specimens are smeared in one side facial area by random table, opposite side smears placebo 28
My god, twice a day, once in the morning and once at night.Facial area dependence test was carried out at the 0th, 14 and 28 day, so as to relax to the whitening of product
Slow effect is assessed.During experiment, it is associated with Evaluation product that subject does not occur erythema, papule, wheal, itch etc.
Skin adverse reaction.
VISIA facial areas integrally shoot to test with dermal melanin value and show, use the spot of the side facial area of test specimens
Severity is obviously improved, and melanin value declines, the increase of skin brightness ITA0 values, and placebo side facial area is without significant change,
Illustrate that preparing whitening according to embodiment 5 releives the effect that facial treatment milk has whitening to highlight the facial area colour of skin.Volunteer is to test
The irritation of sample group and placebo, the colour of skin uniformity, the penetrating degree of the colour of skin, color spot desalination degree and colour of skin whitening degree 5
Investigation result, test specimens, which are also better than, compares placebo.
Claims (9)
1. a kind of composite whitening and the composition for soothing the skin stimulatory function, it is characterised in that：Including following weight percent
Component：Symwhite-337 0.01~1.0%, licoflavone 0.01~5%, Baical Skullcap root P.E 0.01~10%, Radix Glycyrrhizae carries
Take object 0.01~10%, Gotu Kola P.E 0.01~10%, german chamomile extract 0.01~10%, polyalcohol 1~10%, surplus
For water.
2. composite whitening according to claim 1 and the composition for soothing the skin stimulatory function, it is characterised in that：Including with
The component of lower weight percent：Symwhite-337 0.03~0.08%, licoflavone 1~5%, Baical Skullcap root P.E 1~
8%, licorice 0.5~8%, Gotu Kola P.E 0.5~6%, german chamomile extract 0.1~8%, polyalcohol 2~8%,
Surplus is water.
3. composite whitening according to claim 1 and the composition for soothing the skin stimulatory function, it is characterised in that：Including with
The component of lower weight percent：Symwhite-337 0.03~0.06%, licoflavone 1~4%, Baical Skullcap root P.E 2~
8%, licorice 1~6%, Gotu Kola P.E 1~5%, german chamomile extract 0.5~5%, polyalcohol 3~6%, surplus
For water.
4. composite whitening according to any one of claim 1-3 and the composition for soothing the skin stimulatory function, feature
It is, the polyalcohol is propylene glycol or butanediol.
5. composite whitening any one of claim 1-4 and soothe the skin stimulatory function composition preparation method,
It is characterised in that it includes following steps：
(1) licoflavone is sequentially added in water, Baical Skullcap root P.E, licorice, Gotu Kola P.E, german chamomile extract,
It stirs evenly, obtains mixed solution；
(2) Symwhite-337 is dispersed in polyalcohol, is slow added into the mixed solution obtained in step 1), stirs
It mixes uniformly, you can obtain composite whitening and soothe the skin the composition of stimulatory function.
6. a kind of skin preparations for extenal use, which is characterized in that the skin preparations for extenal use includes answering any one of claim 1-4
Close whitening and soothe the skin the composition of stimulatory function, wherein percentage, composite whitening with soothe the skin stimulation work(
The composition of energy accounts for the 1%~50% of skin preparations for extenal use total weight.
7. skin preparations for extenal use according to claim 6, which is characterized in that the dosage form of the skin preparations for extenal use is solution, Gel
Curry, lotion or cream shape.
8. the preparation method of the skin preparations for extenal use described in claim 6 or 7, which is characterized in that comprise the following steps：
1) composite whitening with the composition for soothing the skin stimulatory function is added to the water and be uniformly dissolved；
2) acceptable auxiliary material pharmaceutically or on cosmetics is added in, is uniformly mixed, you can obtain the skin preparations for extenal use.
9. composite whitening any one of claim 1-4 and the composition of stimulatory function is soothed the skin as whitening active
Ingredient and soothe the skin application of the stimulating activity ingredient in cosmetics.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711450619.2A CN108096095A (en) | 2017-12-27 | 2017-12-27 | A kind of composite whitening and composition and its application for soothing the skin stimulatory function |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711450619.2A CN108096095A (en) | 2017-12-27 | 2017-12-27 | A kind of composite whitening and composition and its application for soothing the skin stimulatory function |
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| CN108096095A true CN108096095A (en) | 2018-06-01 |
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| CN201711450619.2A Pending CN108096095A (en) | 2017-12-27 | 2017-12-27 | A kind of composite whitening and composition and its application for soothing the skin stimulatory function |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112754979A (en) * | 2021-02-03 | 2021-05-07 | 广州博裕生物科技有限公司 | Composite plant extract repairing liquid and preparation method thereof |
| CN113384506A (en) * | 2021-07-08 | 2021-09-14 | 江苏瑞霆生物科技有限公司 | Low-irritation plant enzyme whitening nano composition and preparation method and application thereof |
| CN114632040A (en) * | 2022-03-15 | 2022-06-17 | 宝萃生物科技有限公司 | Composition with relieving effect and preparation and application thereof |
| CN115554180A (en) * | 2022-10-24 | 2023-01-03 | 陕西畅想制药有限公司 | 4-butyl resorcinol supramolecular vesicle aggregate and preparation method and cosmetic composition thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102614104A (en) * | 2012-04-24 | 2012-08-01 | 黑龙江农垦东北黑蜂开发有限公司 | Skin-whitening and freckle-dispelling essence and preparation method thereof |
| CN102871863A (en) * | 2012-10-24 | 2013-01-16 | 成都瑞商通银日用品有限公司 | Whitening and water replenishing complex |
| CN104958247A (en) * | 2015-06-30 | 2015-10-07 | 湖南炎帝生物工程有限公司 | Body lotion containing Nostoc sphaeroids extract and preparation method thereof |
| CN106333869A (en) * | 2016-11-02 | 2017-01-18 | 广州美尔生物科技有限公司 | Skin care product having whitening and freckle removing effects and preparation method thereof |
-
2017
- 2017-12-27 CN CN201711450619.2A patent/CN108096095A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102614104A (en) * | 2012-04-24 | 2012-08-01 | 黑龙江农垦东北黑蜂开发有限公司 | Skin-whitening and freckle-dispelling essence and preparation method thereof |
| CN102871863A (en) * | 2012-10-24 | 2013-01-16 | 成都瑞商通银日用品有限公司 | Whitening and water replenishing complex |
| CN104958247A (en) * | 2015-06-30 | 2015-10-07 | 湖南炎帝生物工程有限公司 | Body lotion containing Nostoc sphaeroids extract and preparation method thereof |
| CN106333869A (en) * | 2016-11-02 | 2017-01-18 | 广州美尔生物科技有限公司 | Skin care product having whitening and freckle removing effects and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 裘炳毅等: "《现代化妆品科学与技术（下册）》", 31 March 2016, 中国轻工业出版社 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112754979A (en) * | 2021-02-03 | 2021-05-07 | 广州博裕生物科技有限公司 | Composite plant extract repairing liquid and preparation method thereof |
| CN113384506A (en) * | 2021-07-08 | 2021-09-14 | 江苏瑞霆生物科技有限公司 | Low-irritation plant enzyme whitening nano composition and preparation method and application thereof |
| CN113384506B (en) * | 2021-07-08 | 2022-03-25 | 江苏瑞霆生物科技有限公司 | Low-irritation plant enzyme whitening nano composition and preparation method and application thereof |
| CN114632040A (en) * | 2022-03-15 | 2022-06-17 | 宝萃生物科技有限公司 | Composition with relieving effect and preparation and application thereof |
| CN114632040B (en) * | 2022-03-15 | 2022-09-13 | 宝萃生物科技有限公司 | Composition with relieving effect and preparation and application thereof |
| CN115554180A (en) * | 2022-10-24 | 2023-01-03 | 陕西畅想制药有限公司 | 4-butyl resorcinol supramolecular vesicle aggregate and preparation method and cosmetic composition thereof |
| CN115554180B (en) * | 2022-10-24 | 2023-09-22 | 陕西畅想制药有限公司 | 4-butylresorcinol supermolecule vesicle aggregate, preparation method thereof and cosmetic composition |
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