CN106176566B - Cosmetic composition and preparation method thereof with white-skinned face function - Google Patents
Cosmetic composition and preparation method thereof with white-skinned face function Download PDFInfo
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- CN106176566B CN106176566B CN201610709647.0A CN201610709647A CN106176566B CN 106176566 B CN106176566 B CN 106176566B CN 201610709647 A CN201610709647 A CN 201610709647A CN 106176566 B CN106176566 B CN 106176566B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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Abstract
The present invention relates to a kind of cosmetic compositions with white-skinned face function, and formula includes following materials by weight:Glucityl rutin 0.1% 2%, oxidized resveratrol 0.05% 1%, thyme extract 0.1% 2%, 3 o ethylascorbyls 0.1% 3%, evodia rutaecarpa berry extract 0.1% 5%, Bacillus acidi lactici/pomegranate fruit tunning extract 0.1% 10%.Cosmetic composition of the present invention with white-skinned face function significantly reduces stimulation of the ultraviolet light to skin without adding any chemical sun;The effect of balanced whitening can be played, formula carries out compatibility using mild, safe raw material, and is finally reached collaboration whitening, the effect of efficient whitening.
Description
Technical field
The invention belongs to cosmetic fields, particularly relate to a kind of cosmetic composition and its system with white-skinned face function
Preparation Method.
Background technology
It is well known that human body complexion is mainly determined by the quantity of melanin and distribution.The generation and consumption of melanin
Process mainly has following approach:The external factor such as ultraviolet light stimulate skin, generate inflammatory factor, oxygen radical etc., and then activate
Tyrosinase, and stimulation melanin cell utilizes tyrosine synthesis of melanin, melanin logical in the case where the participation of tyrosinase helps
It crosses dendron and is transferred to horn cell, finally fall off with horn cell.
The historical progress of skin whitening was roughly divided into the next stage:
First stage:It brightens the stage, mainly based on shaded surface, physical whitening ingredients, emphasizes that product enables flesh merely
The whiter apparent characteristic of skin, such as early stage liquid face powder.But it carrys out many drawbacks to skin tape, not only to skin without essence
Property brighten, promote in vain act on, can also the blockings such as pore or sebaceous glands caused by long-time service, influence skin perspiration and metabolism,
Lead to the generation of skin disease (such as local inflammation, acne).Therefore the temporary increasing for brightening a kind of only covering of first stage
In vain.
Second stage:Bleaching stage, often by adding the physics such as the mineral mill stripping ingredients such as ingredient or higher concentration tartaric acid, mill
Stripping or stimulation epidermal keratinocyte make its fast-falling, to achieve the purpose that change skin bleaching, such as scrub cream or skin-changing cream.It is long
Phase use can cause skin immunity to decline, and be a kind of typical palliative ill whitening mode.
Phase III:The local whitening stage, i.e., by adding various whitening compositions, local interference epidermis from different directions
The formation of melanin accelerates its catabolism, and relatively for the former, third generation product is in the understanding of lightening mechanism and application side
There is qualitative leap in face, but it still rests on the whitening stage of limitation.And there are many safety problems in raw material selection:
Lead mercury -- inhibit tyrosinase by replacing the copper needed for tyrosinase effect, bio-toxicity is big, destructible human organ;Hydrogen
Quinone -- cytotoxicity destroys melanocyte;Rhododendrol -- there is hickie in excessive whitening.
But existing whitening product will not generally consider the links of skin-whitening, i.e., from melanin production inducement
(ultraviolet light irradiation), melanin production process discharge process of melanin digestion to the end etc..Therefore it is badly in need of developing a kind of energy temperature
With safe, the skin-lightening cosmetic of the balanced whitening of efficient and energy.
Invention content
In order to solve the above-mentioned problems in the prior art, the present invention provides a kind of mild, safe, efficient and energy
The cosmetic composition of balanced whitening.Compared with single whitening agent, in the case of identical whitening effect, whitening used in the present invention
Agent dosage is obviously relatively low.
The technical purpose of the present invention is achieved through the following technical solutions:
Cosmetic composition of the present invention with white-skinned face function, formula include the raw material of following weight percent
Component:Glucityl rutin 0.1%-2%, oxidized resveratrol 0.05%-1%, thyme extract 0.1%-2%, 3-o- second
Base ascorbic acid 0.1%-3%, evodia rutaecarpa berry extract 0.1%-5%, Bacillus acidi lactici/pomegranate fruit tunning extract
0.1%-10%.
The present invention is it is highly preferred that the formula includes following materials by weight:Glucityl rutin 0.2%-
0.5%, oxidized resveratrol 0.05%-0.2%, thyme extract 0.2%-0.5%, 3-o- ethylascorbyl 0.5%-
1.5%, evodia rutaecarpa berry extract 1%-35%, Bacillus acidi lactici/pomegranate fruit tunning extract 2%-5%.
Further, formula further includes following materials by weight:Moisturizer 0.1%-10%, polyalcohol
5%-15%, thickener 0.1%-2%.
Preferably, formula includes following materials by weight:Moisturizer 2%-4%, polyalcohol 1%-
15%, thickener 0.3%-2%.
Specifically, the moisturizer is selected from glucan and/or amino acid humectant;The polyalcohol is butanediol, the third two
The substance of one or more of alcohol and glycerine;The thickener is in hydroxyethyl cellulose, carbomer, xanthans
One or more kinds of substances.
Further, which is characterized in that its formula further includes following materials by weight:Solubilizer
0.01%-0.2%.
Further, formula further includes following materials by weight:Preservative 0.1%-1%.
Preferably, the solubilizer is selected from Cremophor RH40;The preservative is selected from liquid outstanding person horse, and/or benzene
Oxyethanol and Sensiva SC50 compound ligand (PE90100).If it is the compounding of two kinds of substances, ratio by weight 9 is compounded:
1。
It further include following materials by weight in the present invention:Essence 0.001%-0.1%.
Another technical object of the present invention is to provide a kind of method preparing the cosmetic composition with white-skinned face function, packets
Include following preparation process:
1) raw material components of formula, are divided into A groups, B groups, C groups, each group group by weight percentage is divided into:A groups include more
First alcohol 1%-15%, moisturizer 0.1%-10%, thickener 0.1%-2%, deionized water surplus;B groups include preservative
0.1%-1%, solubilizer 0.01%-0.2%, essence 0.001%-0.1%;C group each components include glucityl rutin 0.1%-
2%, oxidized resveratrol 0.05%-1%, thyme extract 0.1%-2%, 3-o- ethylascorbyl 0.1%-3%, Wu
Fruit of medicinal cornel berry extract 0.1%-5%, Bacillus acidi lactici/pomegranate fruit tunning extract 0.1%-10%;
2), by A group each components be added water phase pot, be heated to 75~80 DEG C, stirring and dissolving is complete, then insulated and stirred 20~
25min;
3) it stirs and is cooled to 30~35 DEG C, each component of B groups, C groups is sequentially added in water phase pot, stirring and dissolving is complete
Entirely.
Beneficial effects of the present invention:
Compared with commercially available lightening compositions, had the beneficial effect that possessed by lightening compositions of the invention:
1, without adding any chemical sun, and stimulation of the ultraviolet light to skin is significantly reduced.
2, the effect of balanced whitening can be played, that is, considers the links of skin-whitening, from melanin production inducement
The links such as (ultraviolet light irradiation), melanin production the process discharge process of melanin digestion to the end consider.
3, lightening compositions of the present invention have selected mild, safe raw material to carry out compatibility, such as glucityl rutin, oxygen
Change resveratrol, thyme extract, 3-o- ethylascorbyls, evodia rutaecarpa berry extract, Bacillus acidi lactici/pomegranate fruit fermentation production
Object extract, and it is finally reached collaboration whitening, the effect of efficient whitening.
Specific implementation mode
In order to make the object, technical solutions and advantages of the present invention definitely, below to the preferred embodiment of the present invention into
The detailed description of row.The weight of cosmetic combinations composition formula of the present invention with white-skinned face function can be kilogram or public
Jin.
There is the present invention the balanced whitening principle of cosmetic composition of white-skinned face function to be:
1), consider from the inducement for preventing melanin production.Enzyme switch technology binds glucose and rutin, makes glucityl reed
The solubility of fourth in water is more many times higher than common rutin, and originally unstable common rutin is become stable glucityl reed
Fourth.And glucityl rutin has extremely strong absorption and superpower light resistance to ultraviolet light, is added in lightening compositions of the present invention
It can be not added with any chemical sun, and significantly reduce stimulation of the ultraviolet light to skin.And then reduce resulting inflammation because
Son and oxygen radical etc., and above-mentioned substance can be such that tyrosinase activity increases, and then increase the generation of melanin.
2), consider from anti-oxidant, Green Tea Extract.Oxidized resveratrol mainly extracts from Yunnan jackfruit, with superpower
Anti-oxidant and Green Tea Extract ability.In vitro technique result shows that it has and tyrosinase and melanin is inhibited to live well
The ability of property.
3), from inhibiting tyrosinase activity and each oxidation reaction of tyrosine building-up process inhibited to consider.3-o- second
Base ascorbic acid has very strong reproducibility, can inhibit tyrosinase activity, reduce generation and the deposition of melanin, reaches beautiful
Contour painting is imitated.Melanin can also be made to be reduced to colourless reproducibility melanin, reach whitening effect.
4), from the transfer process consideration for blocking melanin.Thyme extract confirms to inhibit to drive albumen through research
To the transfer process of melanin.Such inhibition is proved to reach certain whitening effect.And melanin is thin in melanin
The accumulation of intracellular can feed back to skin, to give one melanin production of skin enough signals, to reduce the upper of melanin
Swim generating process.Rest on melanin in melanocyte also can gradual disperse, digestion.
5) improves local skin metabolism, pigment is made gradually to dissipate consideration from local blood circulation is promoted.Evodia rutaecarpa fruit carries
It takes object to come from Chinese Pharmacopoeia, more than one thousand years has been used in China.Belong to monarch drug in a prescription in the theory of traditional Chinese medicine theory " monarch ", has
The effect of promoting the effect of local skin microcirculation, being conducive to metabolism of pigment.
6) considers from the metabolism of acceleration cuticula.After melanin enters cuticula, can together it be taken off with cuticula
It falls.Bacillus acidi lactici/pomegranate fruit tunning extract, which has, promotes cell turnover, accelerates the effect of cuticula metabolism, from
And falling off for melanin can be accelerated.
7) considers from experimental result, and lightening compositions formula of the present invention can be finally reached synergistic result.With list
One whitening agent is compared, and in the case of identical whitening effect, whitening agent dosage will obviously be lacked used in the present invention.
In lightening compositions formula of the present invention, addition glucityl rutin act as preventing the illumination inducement of melanin production.
Oxidized resveratrol act as anti-oxidant, Green Tea Extract.Thyme extract act as blocking the transfer process of melanin.And add
3-o- ethylascorbyls are added to act as inhibiting tyrosinase activity and inhibiting each oxidation reaction of tyrosine building-up process.
Evodia rutaecarpa berry extract act as promoting the blood circulation of epidermis, improves local skin metabolism, pigment is made gradually to dissipate.Lactic acid bar
Bacterium/pomegranate fruit tunning extract act as accelerating the metabolism of cuticula.Above functions substance be it is commercially available, can be from quotient
Industry channel is bought.
Embodiment 1
1. the formula of the cosmetic composition with white-skinned face function
There is the present invention each component of the cosmetic composition of white-skinned face function to be divided into A groups, B groups, C groups.Specifically, by weight
Percentage calculation, the A groups include each component:Deionized water 88.29%, butanediol 5%, glucan 2%, hydroxyethyl cellulose
0.5%;B group each components include liquid outstanding person horse 0.5%, Cremophor RH40 0.2%, essence 0.01%;C group each components
Including glucityl rutin 0.2%, oxidized resveratrol 0.05%, thyme extract 0.2%, 3-o- ethylascorbyls
0.5%, evodia rutaecarpa berry extract 1%, Bacillus acidi lactici/pomegranate fruit tunning extract 2%.
2, the preparation method of the cosmetic composition with white-skinned face function
1) water phase pot is added in A group each components, is heated to 80 DEG C, stirring is complete to dissolving;2) insulated and stirred 20min;3)
Stirring cools to 35 DEG C, and B groups, C group each components are added in water phase pot, and stirring and dissolving is complete, and it is qualified to examine, discharging.
Embodiment 2
1. the formula of the cosmetic composition with white-skinned face function
There is the present invention each component of the cosmetic composition of white-skinned face function to be divided into A groups, B groups, C groups.Specifically, by weight
Percentage calculation, the A groups each component include:Deionized water 78.89%, propylene glycol 10%, glucan 3%, carbomer
0.3%, triethanolamine 0.3%;B group each components include PE90100.6%, Cremophor RH40 0.2%, essence
0.01%;C group each components include glucityl rutin 0.3%, oxidized resveratrol 0.1%, thyme extract 0.3%, 3-o-
Ethylascorbyl 1%, evodia rutaecarpa berry extract 2%, Bacillus acidi lactici/pomegranate fruit tunning extract 3%.
2, the preparation method of the cosmetic composition with white-skinned face function
1) A group each components are added in water phase pot, are heated to 80 DEG C, stirring and dissolving is complete;2) insulated and stirred 20min;3)
Stirring cools to 35 DEG C, and B groups, C group each components are added in water phase pot, and stirring and dissolving is complete, and it is qualified to examine, discharging.
Embodiment 3
1. the formula of the cosmetic composition with white-skinned face function
There is the present invention each component of the cosmetic composition of white-skinned face function to be divided into A groups, B groups, C groups.Specifically, by weight
Percentage calculation, the A groups include each component:Deionized water 68.89%, glycerine 15%, bextran 45 %, carbomer 0.3%,
Triethanolamine 0.3%;B group each components include PE9010 0.6%, Cremophor RH40 0.2%, essence 0.01%;C groups
Each component includes glucityl rutin 0.5%, oxidized resveratrol 0.2%, thyme extract 0.5%, 3-o- ethyl Vitamin Cs
Acid 1.5%, evodia rutaecarpa berry extract 3%, Bacillus acidi lactici/pomegranate fruit tunning extract 5%.
2, the preparation method of the cosmetic composition with white-skinned face function
1) water phase pot is added in A group each components, is heated to 80 DEG C, stirring and dissolving is complete;2) insulated and stirred 20 minutes;3) it stirs
It mixes and cools to 35 DEG C, B groups each component and C group each components are added in water phase pot, stirring and dissolving is complete, and it is qualified to examine, discharging.
Embodiment 4
1. the formula of the cosmetic composition with white-skinned face function
The each component of embodiment 4 is divided into A groups, B groups, C groups.Specifically, count by weight percentage, the A groups, B groups are each
Component is same as Example 1;C group each components include glucityl rutin 0.5%, oxidized resveratrol 0.1%, thyme extract
0.2%, 3-o- ethylascorbyls 1%, evodia rutaecarpa berry extract 0.5%, Bacillus acidi lactici/pomegranate fruit tunning extract
0.5%.
2, the preparation method of the cosmetic composition with white-skinned face function
Preparation method is identical as the preparation method of embodiment 1.
Whitening effect is tested
One, whitening effect variation test
1, test sample:
Embodiment 1 is used as sample A groups and blank control sample B groups.
2, crowd is selected:
Age range --- 25-45 Sui
Each 50 of gender --- men and women
Test season --- December in October-
Region --- In Guangdong Province
3, process is tested:
Select the left and right arm of subject as tested region, random rotation label;By technical staff using test equipment into
Row initial value data acquires;In the tested area (the same area) cleaned by clear water, once in the morning and once at night, during experiment by
Examination position cannot be used except other any cosmetics in addition to by sample;Test article is used continuously eight weeks in subject, and is testing
Period periodically carries out data acquisition.
Statistical analysis, paired t-test, mean value.
In formula:Tn--- tested region changes over time numerical value
T0--- tested region initial value
KTn--- blank control region changes over time numerical value
KT0--- blank control region initial value
4, test equipment
Dermal melanin and ferroheme tester Mexameter MX18 (German CK companies)
5, test index:
MI values characterize the index of melanin, and the measurement range of instrument is 0~999, and measured value is higher, is illustrated black in skin
Pigment content is higher.
6, experimental result:It is shown in Table 1
The case where 1 tester's group mean MI values of table change with the testing time
It is obtained by the above experimental data:Opposite initial value change rate remains negative value, and has certain statistics
Meaning.Opposite blank control change rate also remains negative value.
Finally draw a conclusion:The sample A groups of embodiment 1 relative to blank group have good whitening effect, and with when
Between passage whitening effect become apparent.
Two, lightening compositions of the present invention and traditional whitening agent are the same as additive amount contrast experiment in the case of effect
1, test sample is shown in Table 2:
The formula and preparation method thereof of 2 sample of table
The formula of lightening compositions | Preparation method | |
Sample A | From embodiment 4 | It is same as Example 1 |
Sample B1 | Using alpha-arbutin as whitening component, other components are same as Example 1 | It is same as Example 1 |
Sample B2 | It is whitening component with VC ethylethers, other components are same as Example 1 | It is same as Example 1 |
Sample B3 | It is whitening component with niacinamide, other components are same as Example 1 | It is same as Example 1 |
2, crowd is selected:
Age range --- 25-45 Sui
Each 50 of gender --- men and women
Test season --- December in October-
Region --- In Guangdong Province
3, process is tested:
Select the left and right arm of subject as tested region, random rotation label;
By technical staff initial value data acquisition is carried out using test equipment;
In the tested area (the same area) cleaned by clear water, once in the morning and once at night, during experiment recipient site is not
It can use except other any cosmetics in addition to by sample;
Test article is used continuously eight weeks in subject, and periodically carries out data acquisition dduring test.
4, test equipment
Dermal melanin and ferroheme tester Mexameter MX18 (German CK companies)
5, test index:
MI values are to characterize the index of melanin, and the measurement range of instrument is 0~999, and measured value is higher, illustrates in skin
Melanin content is higher.
6, experiment purpose
Test and whitening agent additive amount needed for the close sample B1-B3 of sample A white-skinned face functions.
7, experimental result
After tested, it is found that B1-B3 reaches whitening effect identical with sample A, the additive amount of whitening agent is respectively required for reaching
Dosage as shown in table 3 below.
The each sample whitening agent usage amount table of comparisons under the conditions of 3 identical whitening effect of table
From experimental result:In the case of identical whitening effect, whitening agent dosage is obviously relatively low used in the present invention, and
There is no irritation after use, product it is safe to use.
Three, security test
Method for testing security:30 triers are selected, the skin care item of embodiment 1-5 are subjected to patch test, pass through naked eyes
Observation, dermoreaction is observed after 24 hours.The extent of reaction and grade scoring standard are shown in Table 4, and test result is shown in Table 5.
4 patch test grade scoring standard of table
5 security test result of table
Embodiment | Negative reaction/people | Suspicious reaction/people |
Embodiment 1 | 30 | 0 |
Embodiment 2 | 30 | 0 |
Embodiment 3 | 30 | 0 |
Embodiment 4 | 30 | 0 |
According to《Cosmetics health specification》2007 editions human skin patch experimental judgment standards, Examples 1 to 4 to human body without
Adverse reaction.The skin whitener of the present invention has good whitening effect, is provided simultaneously with higher safety, mildness.
Obviously, the above embodiment of the present invention be only to clearly illustrate example of the present invention, and not be pair
The restriction of embodiments of the present invention.For those of ordinary skill in the art, may be used also on the basis of the above description
To make other variations or changes in different ways.Here all embodiments can not be exhaustive.It is every to belong to this hair
Row of the obvious changes or variations that bright technical solution is extended out still in protection scope of the present invention.
Claims (10)
1. a kind of cosmetic composition with white-skinned face function, which is characterized in that it is formulated the activity by following weight percent
Raw material components form:Glucityl rutin 0.1%-2%, oxidized resveratrol 0.05%-1%, thyme extract 0.1%-
2%, 3-o- ethylascorbyls 0.1%-3%, evodia rutaecarpa berry extract 0.1%-5%, Bacillus acidi lactici/pomegranate fruit tunning
Extract 0.1%-10%.
2. the cosmetic composition according to claim 1 with white-skinned face function, which is characterized in that its be formulated further include as
The auxiliary material component of lower weight percent:Moisturizer 0.1%-10%, polyalcohol 5%-15%, thickener 0.1%-2%.
3. the cosmetic composition according to claim 2 with white-skinned face function, which is characterized in that it includes as follows that it, which is formulated,
The auxiliary material component of weight percent:Moisturizer 2%-4%, polyalcohol 1%-15%, thickener 0.3%-2%.
4. the cosmetic composition according to claim 3 with white-skinned face function, which is characterized in that the moisturizer is selected from
Glucan and/or amino acid humectant;The polyalcohol is the object of one or more of butanediol, propylene glycol and glycerine
Matter;The thickener is selected from the substance of one or more of hydroxyethyl cellulose, carbomer, xanthans.
5. the cosmetic composition according to claim 1 with white-skinned face function, which is characterized in that its be formulated further include as
The auxiliary material component of lower weight percent:Solubilizer 0.01%-0.2%.
6. the cosmetic composition according to claim 1 with white-skinned face function, which is characterized in that its be formulated further include as
The auxiliary material component of lower weight percent:Preservative 0.1%-1%.
7. the cosmetic composition according to claim 5 with white-skinned face function, which is characterized in that the solubilizer is selected from
Cremophor RH40.
8. the cosmetic composition according to claim 6 with white-skinned face function, which is characterized in that the preservative is selected from
Liquid outstanding person horse, and/or Phenoxyethanol and Sensiva SC50 compound ligand.
9. the cosmetic composition according to claim 1 with white-skinned face function, which is characterized in that its be formulated further include as
The auxiliary material component of lower weight percent:Essence 0.001%-0.1%.
10. a kind of method preparing the cosmetic composition with white-skinned face function, which is characterized in that including following preparation process:
1) raw material components of formula, are divided into A groups, B groups, C groups, each group group by weight percentage is divided into:A groups include polyalcohol
1%-15%, moisturizer 0.1%-10%, thickener 0.1%-2%, deionized water surplus;B groups include preservative 0.1%-
1%, solubilizer 0.01%-0.2%, essence 0.001%-0.1%;C groups are by glucityl rutin 0.1%-2%, the white black false hellebore of oxidation
Alcohol 0.05%-1%, thyme extract 0.1%-2%, 3-o- ethylascorbyl 0.1%-3%, evodia rutaecarpa berry extract
0.1%-5%, Bacillus acidi lactici/pomegranate fruit tunning extract 0.1%-10% compositions;
2), by A group each components be added water phase pot, be heated to 75~80 DEG C, stirring and dissolving is complete, then insulated and stirred 20~
25min;
3) it, stirs and is cooled to 30~35 DEG C, each component of B groups, C groups is sequentially added in water phase pot, stirring and dissolving is complete.
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CN201610709647.0A CN106176566B (en) | 2016-08-23 | 2016-08-23 | Cosmetic composition and preparation method thereof with white-skinned face function |
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Application Number | Priority Date | Filing Date | Title |
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CN201610709647.0A CN106176566B (en) | 2016-08-23 | 2016-08-23 | Cosmetic composition and preparation method thereof with white-skinned face function |
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CN107242982B (en) * | 2017-06-07 | 2020-09-15 | 广州科玛生物科技股份有限公司 | Fair and bright emulsion and preparation method thereof |
CN107157843A (en) * | 2017-06-07 | 2017-09-15 | 广州科玛生物科技股份有限公司 | A kind of fair-skinned bright white toner and preparation method thereof |
CN107281024A (en) * | 2017-06-26 | 2017-10-24 | 上海新高姿化妆品有限公司 | It is a kind of that there is cosmetic composition of collaboration whitening effect and preparation method thereof |
CN107049824A (en) * | 2017-06-27 | 2017-08-18 | 上海新高姿化妆品有限公司 | A kind of composition with white-skinned face function and its application in cosmetics |
CN107802559B (en) * | 2017-12-14 | 2020-09-11 | 广州市科能化妆品科研有限公司 | Whitening composition and preparation method and application thereof |
CN108159027A (en) * | 2018-03-05 | 2018-06-15 | 天津中医药大学 | It is a kind of to cooperate with composition for inhibiting MITF and TRP1 and application thereof |
CN109363964B (en) * | 2018-07-14 | 2021-06-29 | 泉州师范学院 | Oxyresveratrol hydroxypropyl methyl cellulose composite membrane and application thereof |
CN110051590A (en) * | 2019-05-22 | 2019-07-26 | 广州睿森生物科技有限公司 | Whitening, spot composition and cosmetics containing the composition |
CN110772438B (en) * | 2019-11-08 | 2022-07-05 | 中南林业科技大学 | Sunscreen composition containing resveratrol and preparation method and application thereof |
CN111743851B (en) * | 2020-07-09 | 2021-01-12 | 广州市胜梅化妆品有限公司 | Whitening and spot-fading composition and application thereof |
CN115227634A (en) * | 2022-08-31 | 2022-10-25 | 臧海敏 | Whitening and spot-fading composition and preparation method thereof |
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CN104825382A (en) * | 2015-05-26 | 2015-08-12 | 成都肤格特商贸有限公司 | Biotechnology skin-whitening cosmetics |
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CN104825382A (en) * | 2015-05-26 | 2015-08-12 | 成都肤格特商贸有限公司 | Biotechnology skin-whitening cosmetics |
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