CN108066167A - A kind of antibacterial whitening acidity mouthwash of visualization and preparation method thereof - Google Patents
A kind of antibacterial whitening acidity mouthwash of visualization and preparation method thereof Download PDFInfo
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- CN108066167A CN108066167A CN201810137164.7A CN201810137164A CN108066167A CN 108066167 A CN108066167 A CN 108066167A CN 201810137164 A CN201810137164 A CN 201810137164A CN 108066167 A CN108066167 A CN 108066167A
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- Prior art keywords
- mouthwash
- agent
- acidity
- acid
- antibacterial
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/22—Peroxides; Oxygen; Ozone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Abstract
The invention discloses a kind of antibacterial whitening acidity mouthwash of visualization, by forming following weight percentage components：Sweetener 0.003% ~ 0.1%；Acid 0.1%~0.5%；Moisturizer 2%~15%；Essence 0.05%~0.5%；Brightening agent 0.1%~5%；Solubilizer 0.5%~2.5%；Bacteriostatic agent 0.02%~0.05%；Preservative 0.1%~0.4%；Deionized water surplus；The present invention also provides the methods for preparing the antibacterial whitening acidity mouthwash of visualization.The present invention to oral cleaning, dispel implication and antibacterial, hemostasis and anti-inflammation function while, can effectively, the removing of adhesion and staining quick, that thoroughly realize tooth, make tooth nature brilliant white.
Description
Technical field
The present invention relates to oral care product technical field more particularly to a kind of antibacterial whitening acidity mouthwash of visualization and
Its preparation method.
Background technology
With the improvement of living standards, people increasingly improve the attention rate of oral health, common oral care is also no longer
It is confined to brush teeth twice sooner or later, the species and form demand to oral care product tend to diversification and fashion-orientation.Mouthwash is
Through into the necessity in for people's lives, it is easy to use, and effect can be equal to toothpaste, and use is more convenient than toothpaste, but mesh
The mouthwash of preceding market often act on it is single, and for a long time use protective effect is not had to tooth.It is also, existing at present
The acid-base value of mouthwash be generally neutrality, main function include antibacterial bacteriostatic, improve oral peculiar smell, anti-inflammatory, cleaning oral cavity it is thin
Bacterium and tartar etc., species include Chinese medicine draft class, natural plant extracts class and drug ingedient composite class.
CN103385821A discloses a kind of mouthwash of deep layer removal tartar, and constituent has：Glycerine, polyoxy third
Alkene, western pyrrole chloramines, peppermint, motherwort extracting solution, tea polyphenols, strontium chloride, deionized water.
105687083 A of CN disclose a kind of antibacterial hemostasis mouthwash and preparation method thereof, and the mouthwash is by following weight
Raw material be made：0.5~1 part of activated calcium powder, 0.1~2 part of Honegsukle flower P.E, 0.1~1.5 part of propolis, Paeonol 0.2~
0.5 part, 0.1~2 part of deep sea salt, 0.1~0.5 part of mint extract, 0.5~3 part of stevioside, 0.5~1 part of loguat leaf, eucalyptus
0.1~0.3 part of oil, 2~3 parts of old tea liquid, 90~95 parts of pure water.
A kind of long-acting bacteriostatic type mouthwashes of 106038389 A of CN, using deionized water as main component, and at least add
Added with the combination of phellodendron extract, capillary extract, Andrographis Paniculata and Herba Verbenae.This case is extracted using Cortex Phellodendri
The mode that object, capillary extract, Andrographis Paniculata and Herba Verbenae are used in combination, can play quickly prevents gum from going out
The effect of blood, long-acting inhibition oral bacteria, achieve the purpose that treat both principal and secondary aspect of disease.
Various mouthwashes described in above-mentioned patent, although play the antibacterial anti-inflammatory to tooth and oral cavity, cleaning oral cavity and
Tooth and the effect for being effectively improved oral peculiar smell, but it is neutrality, the effect of cleaning tartar and oral foreign body is not
Substantially, how effectively, quickly, thoroughly realize the removing of the adhesion and staining of tooth, keep tooth brilliant white, simultaneously
It plays to tooth and oral antimicrobial anti-inflammatory effects, is to restrict the problem that current mouth cavity daily nurses industry, and pure Chinese medicine
The mouthwash of ingredient primarily serves the effect of reparation, anti-inflammatory, and the Chinese medicine effect for acting on outside is often slow, for tooth
Lightening effect is not obvious.
The content of the invention
In view of the deficienciess of the prior art, the technical problem to be solved by the invention is to provide it is a kind of to oral cleaning,
While dispelling implication and antibacterial, hemostasis and anti-inflammation function, make tooth nature brilliant white the antibacterial whitening acidity mouthwash of visualization and
Its preparation method.
In order to solve the above technical problems, the technical solution used in the present invention is：A kind of antibacterial whitening acidity of visualization is gargled
Saliva, by forming following weight percentage components：
Sweetener 0.003% ~ 0.1%；
Acid 0.1%~0.5%；
Moisturizer 2%~15%；
Essence 0.05%~0.5%；
Brightening agent 0.1%~5%；
Solubilizer 0.5%~2.5%；
Bacteriostatic agent 0.02%~0.05%；
Preservative 0.1%~0.4%；
Deionized water surplus；
The PH of the mouthrinse product is 3~5.
The antibacterial whitening acidity mouthwash of above-mentioned visualization, by forming following weight percentage components：
Sweetener 0.05%；
Acid 0.25%；
Moisturizer 8%；
Essence 0.3%；
Brightening agent 2.5%；
Solubilizer 1.5%；
Bacteriostatic agent 0.03%；
Preservative 0.2%；
Deionized water surplus；
The PH of the mouthrinse product is 4.
The antibacterial whitening acidity mouthwash of above-mentioned visualization, the sweetener for saccharin sodium, D-sorbite, Sucralose,
One or more in Aspartame, honey element, acid are malic acid, and moisturizer is one in glycerine, sorbierite, propylene glycol
Kind is several, and essence is the fruit such as green tea, spearmint, honey peach perfume or the fragrance of a flower, and solubilizer hydrogenates castor for polysorbas20 or PEG-40
Sesame oil, brightening agent are hydrogen peroxide, and preservative is potassium sorbate, one or more of sodium benzoate, methyl hydroxybenzoate, the suppression
Microbial inoculum is Domiphen bromide.
The antibacterial whitening acidity mouthwash of above-mentioned visualization, the mouthwash also added with weight percent be 0.5% it is cool
Taste agent, the coolant agent are menthol.
It is a kind of to prepare the method for visualizing antibacterial whitening acidity mouthwash, include the following steps：
（1）, sweetener and acid are added in stirring and dissolving in water deionization, then moisturizer is added in aqueous solution, stirring is equal
It is even and form finely dispersed water-soluble clarified solution；
（2）, solubilizer, essence stirred to form uniform oily solution；
（3）, in the state of stirring, oily solution is slowly added into water-soluble clarified solution, be uniformly mixed；
（4）, by brightening agent, bacteriostatic agent, preservative add in step（3）In the aqueous solution of acquisition, it is mixed evenly；
（5）, stop stirring, stand 24 it is small when, filtering, after aseptic process PH be 3~5 mouthwash finished product.
The preparation method of the above-mentioned antibacterial whitening acidity mouthwash of visualization, the step（2）Middle addition weight percent
For 0.5% coolant agent.
The preparation method of the above-mentioned antibacterial whitening acidity mouthwash of visualization, the sweetener is saccharin sodium, D-sorbite,
One or more in Sucralose, Aspartame, honey element, acid are malic acid, and moisturizer is glycerine, sorbierite, third
One or more of glycol, essence for the fruit such as green tea, spearmint, honey peach are fragrant or the fragrance of a flower, solubilizer for polysorbas20 or
Cremophor RH40, brightening agent are hydrogen peroxide, and preservative is potassium sorbate, one kind in sodium benzoate, methyl hydroxybenzoate
Or it is several, the bacteriostatic agent is Domiphen bromide.
The preparation method of the above-mentioned antibacterial whitening acidity mouthwash of visualization, the coolant agent are menthol.
The present invention, which visualizes the advantages of antibacterial whitening acidity mouthwash and preparation method thereof, is：It adds acid ingredient and brightens
Agent so that the mouthwash in acidity, to oral cleaning, dispel implication and antibacterial hemostatic function while, can effectively, quickly,
It thoroughly realizes the removing of the adhesion and staining of tooth, keeps tooth brilliant white.Mouthwash of the present invention is applied widely,
It is easy to use, there is cleaning, antibacterial, anti-caries and fresh breath, it is without any side effects；This mouthwash formula is only
It is special, fastidious, manufacturing method is simple, by multiple clinical research, to because of pathogenic bacteria such as Candida albicans, staphylococcus aureuses
Caused oral inflammation has unique antibacterial anti-inflammatory, analgesic promoting muscle growth functions, can effectively inhibit the formation of oral inflammation, maintain mouth
Chamber bacterium state balances, and moment cleaning oral cavity, control effect is good, is the external application type oral cavity medicine that a kind of preferable prevention is integrated with treatment
Object.
Specific embodiment
The present invention is described in further details with reference to specific embodiment；
Embodiment 1：
A kind of antibacterial whitening acidity mouthwash of visualization of the present embodiment, by forming following weight percentage components：Sweetener
0.003%；0.1 % of acid；Moisturizer 2%；Essence 0.05%；Brightening agent 0.1%；Solubilizer 0.5%；Bacteriostatic agent 0.02%；It is anti-
Rotten agent 0.1%；Deionized water surplus；The PH of the mouthrinse product is 5.Wherein, sweetener is saccharin sodium, D-sorbite, trichlorine
Sucrose, acid are malic acid, and moisturizer is glycerine, sorbierite, and essence is the green tea fragrance of a flower, and solubilizer is polysorbas20, brightening agent
For hydrogen peroxide, preservative is potassium sorbate, sodium benzoate, and bacteriostatic agent uses Domiphen bromide.The mouthwash is also added with weight
Percentage is 0.5% coolant agent.In the present embodiment, coolant agent is menthol.
The present embodiment prepares the method for visualizing antibacterial whitening acidity mouthwash, includes the following steps：
（1）, sweetener and acid are added in stirring and dissolving in water deionization, then moisturizer is added in aqueous solution, stirring is equal
It is even and form finely dispersed water-soluble clarified solution；
（2）, solubilizer, essence, 0.5% coolant agent stirred to form uniform oily solution；
（3）, in the state of stirring, oily solution is slowly added into water-soluble clarified solution, be uniformly mixed；
（4）, by brightening agent, bacteriostatic agent, preservative add in step（3）In the aqueous solution of acquisition, it is mixed evenly；
（5）, stop stirring, stand 24 it is small when, filtering, after aseptic process PH be 5 mouthwash finished product.
Wherein, sweetener is saccharin sodium, D-sorbite, Sucralose, and acid is malic acid, and moisturizer is glycerine, mountain
Pears alcohol, essence are the green tea fragrance of a flower, and solubilizer is polysorbas20, and brightening agent is hydrogen peroxide, and preservative is potassium sorbate, benzoic acid
Sodium, bacteriostatic agent use Domiphen bromide.The mouthwash is also added with the coolant agent that weight percent is 0.5%.It is cool in the present embodiment
Taste agent is menthol.
Embodiment 2：
A kind of antibacterial whitening acidity mouthwash of visualization of the present embodiment, by forming following weight percentage components：Sweetener
0.05%；Acid 0.25%；Moisturizer 8%；Essence 0.3%；Brightening agent 2.5%；Solubilizer 1.5%；Bacteriostatic agent 0.03%；Preservative
0.2%；Deionized water surplus；The PH of the mouthrinse product is 4.Wherein, sweetener is D-sorbite, Sucralose, A Siba
Sweet tea, acid are malic acid, and moisturizer is sorbierite, propylene glycol, and essence is the spearmint fragrance of a flower, and solubilizer hydrogenates castor for PEG-40
Sesame oil, brightening agent are hydrogen peroxide, and preservative is sodium benzoate, methyl hydroxybenzoate, and bacteriostatic agent uses Domiphen bromide.Mouthwash also adds
There is the coolant agent that weight percent is 0.5%, in the present embodiment, coolant agent is menthol.
The present embodiment prepares the method for visualizing antibacterial whitening acidity mouthwash, includes the following steps：
（1）, sweetener and acid are added in stirring and dissolving in water deionization, then moisturizer is added in aqueous solution, stirring is equal
It is even and form finely dispersed water-soluble clarified solution；
（2）, solubilizer, essence, 0.5% coolant agent stirred to form uniform oily solution；
（3）, in the state of stirring, oily solution is slowly added into water-soluble clarified solution, be uniformly mixed；
（4）, by brightening agent, bacteriostatic agent, preservative add in step（3）In the aqueous solution of acquisition, it is mixed evenly；
（5）, stop stirring, stand 24 it is small when, filtering, after aseptic process PH be 4 mouthwash finished product.
Wherein, sweetener is D-sorbite, Sucralose, Aspartame, and acid is malic acid, and moisturizer is sorb
Alcohol, propylene glycol, essence are the spearmint fragrance of a flower, and solubilizer is Cremophor RH40, and brightening agent is hydrogen peroxide, and preservative is
Sodium benzoate, methyl hydroxybenzoate, bacteriostatic agent use Domiphen bromide.Mouthwash is also added with the coolant agent that weight percent is 0.5%, this
In embodiment, coolant agent is menthol.
Embodiment 3：
A kind of antibacterial whitening acidity mouthwash of visualization of the present embodiment, by forming following weight percentage components：Sweetener
0.1%；Acid 0.5%；Moisturizer 15%；Essence 0.5%；Brightening agent 5%；Solubilizer 2.5%；Bacteriostatic agent 0.05%；Preservative
0.4%；Deionized water surplus；The PH of the mouthrinse product is 3.Wherein, sweetener is Sucralose, Aspartame, sweetness
Element, acid are malic acid, and moisturizer is glycerine, propylene glycol, and essence is fragrant for honey peach fruit, and solubilizer is polysorbas20, is brightened
Agent is hydrogen peroxide, and preservative is potassium sorbate, methyl hydroxybenzoate, and bacteriostatic agent uses Domiphen bromide.Mouthrinse components in the present embodiment
Also added with the coolant agent that weight percent is 0.5%, the coolant agent is menthol.
The present embodiment prepares the method for visualizing antibacterial whitening acidity mouthwash, includes the following steps：
（1）, sweetener and acid are added in stirring and dissolving in water deionization, then moisturizer is added in aqueous solution, stirring is equal
It is even and form finely dispersed water-soluble clarified solution；
（2）, solubilizer, essence, 0.5% coolant agent stirred to form uniform oily solution；
（3）, in the state of stirring, oily solution is slowly added into water-soluble clarified solution, be uniformly mixed；
（4）, by brightening agent, bacteriostatic agent, preservative add in step（3）In the aqueous solution of acquisition, it is mixed evenly；
（5）, stop stirring, stand 24 it is small when, filtering, after aseptic process PH be 3 mouthwash finished product.
Wherein, sweetener is Sucralose, Aspartame, honey element, and acid is malic acid, and moisturizer is glycerine, third
Glycol, essence is fragrant for honey peach fruit, and solubilizer is polysorbas20, and brightening agent is hydrogen peroxide, and preservative is potassium sorbate, oxybenzene
Methyl esters, bacteriostatic agent use Domiphen bromide.Mouthrinse components are also added with the coolant agent that weight percent is 0.5%, institute in the present embodiment
Coolant agent is stated as menthol.
Certainly, it is limitation of the present invention that above description, which is not, and the present invention is also not limited to the example above, the art
Those of ordinary skill, in the essential scope of the present invention, the variations, modifications, additions or substitutions made should all belong to the present invention
Protection domain.
Claims (8)
1. a kind of antibacterial whitening acidity mouthwash of visualization, which is characterized in that by forming following weight percentage components：
Sweetener 0.003% ~ 0.1%；
Acid 0.1%~0.5%；
Moisturizer 2%~15%；
Essence 0.05%~0.5%；
Brightening agent 0.1%~5%；
Solubilizer 0.5%~2.5%；
Bacteriostatic agent 0.02%~0.05%；
Preservative 0.1%~0.4%；
Deionized water surplus；
The PH of the mouthrinse product is 3~5.
2. the antibacterial whitening acidity mouthwash of visualization according to claim 1, it is characterized in that, by following weight percent
Component forms：
Sweetener 0.05%；
Acid 0.25%；
Moisturizer 8%；
Essence 0.3%；
Brightening agent 2.5%；
Solubilizer 1.5%；
Bacteriostatic agent 0.03%；
Preservative 0.2%；
Deionized water surplus；
The PH of the mouthrinse product is 4.
3. the antibacterial whitening acidity mouthwash of visualization according to claim 1, it is characterized in that：The sweetener is saccharin
One or more in sodium, D-sorbite, Sucralose, Aspartame, honey element, acid are malic acid, and moisturizer is sweet
One or more of oil, sorbierite, propylene glycol, essence is the fruit such as green tea, spearmint, honey peach is fragrant or the fragrance of a flower, solubilizer
For polysorbas20 or Cremophor RH40, brightening agent is hydrogen peroxide, and preservative is potassium sorbate, sodium benzoate, oxybenzene first
One or more of ester, the bacteriostatic agent are Domiphen bromide.
4. the antibacterial whitening acidity mouthwash of visualization according to claim 1, it is characterized in that：The mouthwash is also added with
Weight percent is 0.5% coolant agent, and the coolant agent is menthol.
5. a kind of prepare the method for visualizing antibacterial whitening acidity mouthwash, which is characterized in that includes the following steps：
（1）, sweetener and acid are added in stirring and dissolving in water deionization, then moisturizer is added in aqueous solution, stirring is equal
It is even and form finely dispersed water-soluble clarified solution；
（2）, solubilizer, essence stirred to form uniform oily solution；
（3）, in the state of stirring, oily solution is slowly added into water-soluble clarified solution, be uniformly mixed；
（4）, by brightening agent, bacteriostatic agent, preservative add in step（3）In the aqueous solution of acquisition, it is mixed evenly；
（5）, stop stirring, stand 24 it is small when, filtering, after aseptic process PH be 3~5 mouthwash finished product.
6. the preparation method of the antibacterial whitening acidity mouthwash of visualization according to claim 5, it is characterized in that：The step
（2）The coolant agent that middle addition weight percent is 0.5%.
7. the preparation method of the antibacterial whitening acidity mouthwash of visualization according to claim 5, it is characterized in that：The sweet taste
Agent is saccharin sodium, the one or more in D-sorbite, Sucralose, Aspartame, honey element, and acid is malic acid, is protected
Humectant is one or more of glycerine, sorbierite, propylene glycol, and essence is the fruit such as green tea, spearmint, honey peach perfume or flower
Perfume (or spice), solubilizer are polysorbas20 or Cremophor RH40, and brightening agent is hydrogen peroxide, and preservative is potassium sorbate, benzoic acid
One or more of sodium, methyl hydroxybenzoate, the bacteriostatic agent are Domiphen bromide.
8. the preparation method of the antibacterial whitening acidity mouthwash of visualization according to claim 6, it is characterized in that：The cool taste
Agent is menthol.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810137164.7A CN108066167A (en) | 2018-02-10 | 2018-02-10 | A kind of antibacterial whitening acidity mouthwash of visualization and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810137164.7A CN108066167A (en) | 2018-02-10 | 2018-02-10 | A kind of antibacterial whitening acidity mouthwash of visualization and preparation method thereof |
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| CN108066167A true CN108066167A (en) | 2018-05-25 |
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| CN114601750A (en) * | 2022-02-28 | 2022-06-10 | 陕西化工研究院有限公司 | Preservative composition for oral cleaning and nursing products and preparation method and application thereof |
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