CN108064251A - 碳酸酐酶ix特异性嵌合抗原受体及其使用方法 - Google Patents

碳酸酐酶ix特异性嵌合抗原受体及其使用方法 Download PDF

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CN108064251A
CN108064251A CN201580068869.2A CN201580068869A CN108064251A CN 108064251 A CN108064251 A CN 108064251A CN 201580068869 A CN201580068869 A CN 201580068869A CN 108064251 A CN108064251 A CN 108064251A
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cells
amino acid
acid sequence
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cell
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W.A.马拉斯科
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Dana Farber Cancer Institute Inc
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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CN201580068869.2A 2014-12-19 2015-12-21 碳酸酐酶ix特异性嵌合抗原受体及其使用方法 Pending CN108064251A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462094596P 2014-12-19 2014-12-19
US62/094596 2014-12-19
PCT/US2015/067178 WO2016100980A1 (en) 2014-12-19 2015-12-21 Carbonic anhydrase ix specific chimeric antigen receptors and methods of use thereof

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CN108064251A true CN108064251A (zh) 2018-05-22

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US (3) US10870705B2 (https=)
EP (1) EP3233901A1 (https=)
JP (1) JP2018500337A (https=)
KR (1) KR20170093248A (https=)
CN (1) CN108064251A (https=)
AU (1) AU2015364240A1 (https=)
BR (1) BR112017013177A2 (https=)
CA (1) CA2968555A1 (https=)
IL (1) IL252366A0 (https=)
RU (1) RU2017125735A (https=)
WO (1) WO2016100980A1 (https=)

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CN109705225A (zh) * 2019-01-21 2019-05-03 徐州医科大学 一种抗人caix抗原的嵌合抗原受体及其应用
CN113045665A (zh) * 2021-03-22 2021-06-29 徐州医科大学 一种hvem共刺激信号驱动的caix-car-t细胞及其制备方法和应用
CN114127120A (zh) * 2019-05-06 2022-03-01 纳维再生科技股份有限公司 抗-碳酸酐酶ix抗体
CN114423790A (zh) * 2019-09-10 2022-04-29 普米斯生物技术(珠海)有限公司 靶向caix抗原的纳米抗体及其应用
CN114502781A (zh) * 2019-09-20 2022-05-13 纳维再生科技股份有限公司 个人化癌症免疫治疗
CN116102662A (zh) * 2022-10-10 2023-05-12 武汉波睿达生物科技有限公司 一种靶向ca9的融合嵌合抗原受体、重组表达载体及其应用

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BR112017013176A2 (en) * 2014-12-19 2018-05-15 Dana-Farber Cancer Institute Inc. chimeric antigen receptors and methods for using them
JP2020512284A (ja) * 2016-12-22 2020-04-23 ウィンドミル セラピューティクス インコーポレイテッド 免疫系調節組成物および方法
KR20200143672A (ko) * 2018-02-02 2020-12-24 카르스젠 테라퓨틱스 컴퍼니, 리미티드 세포 면역 치료의 조합
WO2020113224A2 (en) * 2018-11-30 2020-06-04 Dana-Farber Cancer Institute, Inc. Chimeric antigen receptor factories and methods of use thereof
TWI869344B (zh) * 2019-05-06 2025-01-11 納維再生科技股份有限公司 抗-碳酸酐酶ix抗體
CN118852348A (zh) * 2022-02-11 2024-10-29 C-比奥麦克斯有限公司 靶向碳酸酐酶ix的肽配体、包含其的肽结构体及它们的用途
KR20250158048A (ko) 2023-03-03 2025-11-05 아스널 바이오사이언시스, 인크. Psma 및 ca9을 표적으로 하는 시스템
WO2025064539A1 (en) 2023-09-19 2025-03-27 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Herv-e antibodies and methods of their use

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109705225A (zh) * 2019-01-21 2019-05-03 徐州医科大学 一种抗人caix抗原的嵌合抗原受体及其应用
CN109705225B (zh) * 2019-01-21 2022-02-22 徐州医科大学 一种抗人caix抗原的嵌合抗原受体及其应用
CN114127120A (zh) * 2019-05-06 2022-03-01 纳维再生科技股份有限公司 抗-碳酸酐酶ix抗体
US12351645B2 (en) 2019-05-06 2025-07-08 Navi Bio-Therapeuticis, Inc. Anti-carbonic anhydrase IX antibody
CN114423790A (zh) * 2019-09-10 2022-04-29 普米斯生物技术(珠海)有限公司 靶向caix抗原的纳米抗体及其应用
CN114423790B (zh) * 2019-09-10 2024-11-05 普米斯生物技术(珠海)有限公司 靶向caix抗原的纳米抗体及其应用
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