CN108030798A - Honeysuckle extracting method, honeysuckle dried cream powder and honeysuckle detoxicating capsule and preparation method - Google Patents
Honeysuckle extracting method, honeysuckle dried cream powder and honeysuckle detoxicating capsule and preparation method Download PDFInfo
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Abstract
The present invention relates to field of Chinese herbal medicine technology, and in particular to honeysuckle extracting method, honeysuckle dried cream powder and honeysuckle detoxicating capsule and preparation method, the honeysuckle extracting method include：(1) once decoct；(2) secondary decoction；(3) it is concentrated under reduced pressure；(4) it is dried in vacuo, the present invention uses a kind of new dynamic vacuum low-temperature extraction method, ensure that the extraction of antibiotic effective ingredient is complete, improve pharmaceutical effectiveness and medicinal material utilization rate, and influence factor is inquired into, experiment is optimized, finally extracting obtained honeysuckle dried cream powder has higher chlorogenic acid content, it is easy to spread and extracting method is easy and effective.In addition, present invention also offers the detoxicating capsule using the honeysuckle dried cream powder as monarch drug in a prescription, which is entirely formulated reasonable compatibility, has the effect of very high to clearing heat and detoxicating and treatment flu, and pharmacological property relaxes, and is easily absorbed by the human body.
Description
Technical field
The present invention relates to field of Chinese herbal medicine technology, and in particular to honeysuckle extracting method, honeysuckle dried cream powder and honeysuckle
Detoxicating capsule and preparation method.
Background technology
Honeysuckle is also known as honeysuckle, honeysuckle flower, it is the dry flower of caprifoliaceae plant, is clearing heat and detoxicating, wind-heat dissipating normal
With Chinese medicine, its principle active component is Chlorogenic acid, and Chlorogenic acid medicinal history is long, has antibacterial, antiviral, hepatic cholagogic work(
Effect etc., all the time extracts effective ingredient of honeysuckle, and the extracting method of conventional Chlorogenic acid has that water carries milk of lime, water carries
A variety of common methods such as method, the water extracting alcohol precipitation method, dilute alcohol extraction method, it is relatively low that these types of method obtains Chlorogenic acid content, chlorogenic acid
Recovery rate is relatively low, and honeysuckle is not fully utilized, and causes the wasting of resources, and dilute alcohol extraction method is a kind of presently preferred extraction work
Skill, but it is also not high to obtain chlorogenic acid content.
And because existing Honegsukle flower P.E chlorogenic acid content is not high, Honegsukle flower P.E is all generally conduct
Adjuvant, but honeysuckle is good at clearing heat and detoxicating, on the effect of clearing heat and detoxicating be also pole using honeysuckle as the capsule of monarch drug in a prescription
High, but it is fewer in the prior art as the composition of monarch drug in a prescription using honeysuckle.
The content of the invention
In order to overcome shortcoming and defect existing in the prior art, it is an object of the invention to provide a kind of carrying for honeysuckle
Method is taken, this method is simple and practical, and few, ultrahigh in efficiency is destroyed to beneficiating ingredient；Another object of the present invention is to provide use
The honeysuckle dried cream powder with high chlorogenic acid content that this method is extracted；It is a kind of that another object of the present invention also resides in offer
Clearing heat and detoxicating honeysuckle capsule and preparation method thereof.
The purpose of the present invention is achieved through the following technical solutions：
A kind of honeysuckle extracting method, it is characterised in that：Include the following steps：
(1) once decoct：Honeysuckle is added into the water of the honeysuckle 8-12 times of weight, obtains an immersion liquid, it is right
Immersion liquid is vacuumized, and being heated to 60-80 DEG C makes an immersion liquid seethe with excitement, and after keeping the temperature 1-3h, is filtered, is once filtered
Liquid and filter residue；
(2) secondary decoction：The filter residue that step (1) obtains is added into the water of the filter residue 7-9 times of weight, is obtained secondary
Immersion liquid, vacuumizes secondary immersion liquid, and being heated to 60-80 DEG C makes secondary immersion liquid seethe with excitement, and after keeping the temperature 1-3h, is filtered, obtained
To secondary filtrate；
(3) it is concentrated under reduced pressure：After the secondary filtrate that the first-time filtrate and step (2) that step (1) is obtained obtain merges,
It is concentrated under reduced pressure, obtains the medicinal extract that relative density is 1.20-1.30；
(4) it is dried in vacuo：The medicinal extract that step (3) obtains is dried in vacuo, that is, obtains honeysuckle dried cream powder.
The present invention uses a kind of new dynamic vacuum low-temperature extraction method, ensures that the extraction of antibiotic effective ingredient is complete, carries
High pharmaceutical effectiveness and medicinal material utilization rate, and influence factor is inquired into, experiment is optimized, finally extracts obtained gold
Honeysuckle flower dried cream powder has higher chlorogenic acid content, and extracting method is easy and effective, easy to spread.
Wherein, during the step (1) once decocts, honeysuckle is added into the water of 10 times of weight of honeysuckle, is obtained
To an immersion liquid, an immersion liquid is vacuumized, being heated to 60-80 DEG C makes an immersion liquid seethe with excitement, and after keeping the temperature 2h, carries out
Filter, obtains first-time filtrate and filter residue.By the further optimization to test parameters, the recovery rate and effectively of chlorogenic acid can be improved
Control cost.
Wherein, in the secondary decoction of the step (2), the filter residue that step (1) obtains is added to 8 times of weight of filter residue
In water, secondary immersion liquid is obtained, secondary immersion liquid is vacuumized, being heated to 60-80 DEG C makes secondary immersion liquid seethe with excitement, after keeping the temperature 2h,
Filtered, obtain secondary filtrate.By the further optimization to test parameters, the recovery rate and effectively of chlorogenic acid can be improved
Control cost.
Wherein, in the step (1) and step (2), the precision of filtering is 80-120 mesh.Control filtering accuracy can have
Impurity trapped and dud are imitated, and passes through the antipathogenic compositions such as chlorogenic acid.
Wherein, during the step (3) is concentrated under reduced pressure, it is 65-85 DEG C to control the filtrate temperature after merging, and control is concentrated under reduced pressure
Air pressure be -0.08MPa~-0.03MPa.The filtrate temperature after air pressure and merging when control is concentrated under reduced pressure, can improve
Be concentrated under reduced pressure efficiency, and reduces high temperature demands, avoids destruction of the high temperature to antibiotic effective ingredient.
In step (4) vacuum drying, vacuum drying mode is vacuum belt type drying, and vacuum belt type drying is excessively program-controlled
The temperature of medicinal extract processed is 40-80 DEG C.Band-type vacuum drier is that a kind of continuous feed, the contact vacuum of continuous discharge form are done
Dry equipment, drying temperature is relatively low, can keep the color of Honegsukle flower P.E to greatest extent, obtain the gold and silver of high quality
Flower dried cream powder.
The present invention also provides a kind of honeysuckle dried cream powder, is made by honeysuckle extracting method as described above, the gold and silver
The chlorogenic acid content of flower dried cream powder is not less than 3wt%.The content of chlorogenic acid detects to obtain by National Pharmacopeia, and detection method is such as
Under：
According to high effective liquid chromatography for measuring
Chromatographic condition and system suitability are using octadecyl silane as filler, using acetonitrile as mobile phase A, with
0.4% phosphoric acid solution is Mobile phase B；Detection wavelength is 327nm, and number of theoretical plate is calculated by chlorogenic acid peak should be not less than 2000.
The preparation of reference substance solution takes chlorogenic acid reference substance appropriate, and accurate essence is fixed, adds 50% methanol that every 1ml is made and contains 40 ц g
Solution to obtain the final product.
The preparation of test solution takes this product honeysuckle dried cream powder 0.1g, accurately weighed, puts in 100ml measuring bottles, adds 50%
Appropriate methanol, is ultrasonically treated (power 500W, frequency 40kH) 30 minutes, lets cool, and adds 50% methanol to shake up to scale, filter, take
Subsequent filtrate, to obtain the final product.
Determination method is accurate to draw reference substance solution and each 10 ц l of test solution, injects liquid chromatograph, measures, to obtain the final product.
Honeysuckle dried cream powder is based on dry product, containing chlorogenic acid (C16H1809) be：3%-5%.
The present invention also provides a kind of honeysuckle detoxicating capsule, including capsule and the removing toxic substances composition being installed in capsule, institute
Stating removing toxic substances composition includes the raw material of following parts by weight：
Preferably, the raw material of following parts by weight is further included：
It is further preferred that the removing toxic substances composition is made of the raw material of following weight fraction：
Wherein, the honeysuckle dried cream powder is as above to lift honeysuckle dried cream powder made from method.
Wherein, the preparation method of the honeysuckle detoxicating capsule is：The raw material removed outside honeysuckle dried cream powder is crushed,
It is fitted into after being mixed with honeysuckle dried cream powder in capsule, that is, obtains the honeysuckle detoxicating capsule.
Honeysuckle is sweet in flavor cold in nature, and return lung, the heart, stomach, are longer than clearing heat and detoxicating, dispelling wind and heat from the body, to control malignant boil, sore, carbuncle, swollen monarch
Medicine, and the honeysuckle dried cream powder that uses of the present invention be rich in chlorogenic acid, even more with antibacterial, antiviral, to increase white blood cell, liver protection sharp
Courage, antitumor, lowering blood pressure and blood fat, remove the effect such as free radical and stimulating central nervous system system.
Field pennycress, cool in nature, acrid flavour, hardship, have effects that the clearing heat and detoxicating, carbuncle that disappears apocenosis, stasis-dispelling and pain-killing.
Wild chrysanthemum, meridian distribution of property and flavor are bitter, pungent, are slightly cold, Return liver, the heart channel of Hang-Shaoyin, have the function that clearing heat and detoxicating, detumescence, can be extensive
For treating anemopyretic cold, pneumonia, diphtheria, gastroenteritis, hypertension, furunculosis carbuncle swells, abscess of throat, wind-fire red eye, dizziness of having a headache
Etc. disease.
Fructus Forsythiae, it is bitter, it is slightly cold.Return lung, the heart, gallbladder channel.It is clearing heat and detoxicating, dispersing swelling and dissipating binds, for ulcer, scrofula, acute mastitis, erysipelas,
Anemopyretic cold, warm disease from the beginning of, warm join the army, hyperpyrexia polydipsia, coma hair spot, heat gonorrhea renal shutdown.
Herba Andrographitis, bitter, trembles with fear.The thoughts of returning home, lung, large intestine, bladder warp.It is clearing heat and detoxicating, cool blood, detumescence.For cold, fever, pharynx
Larynx swells and ache, aphthae, pertussis overstrain cough, dysentery, puckery pain of heat gonorrhea, carbuncle swells sore, venomous snake bite.
Frankincense, acrid flavour is bitter, temperature.Enter the heart, liver, the spleen channel.Regulating qi and activating blood, analgesic therapy, chases after poison.
Myrrh, it is bitter, it is pungent, put down.Enter liver, spleen, the heart, kidney channel.Dissipate blood stasis eliminatings, detumescence ding-tong.
Windproof, acrid-sweet flavor slightly warm in nature, delivers relieve heat, expel endogenous wind to relieve convulsion.
Levisticum, acrid flavour, hardship, temperature；Enter lung, spleen, kidney three to pass through, there is dispelling wind removing toxic substances, promoting blood circulation, the effect of analgesic.
Radix glycyrrhizae, sweet in flavor, mild-natured, the thoughts of returning home, lung, spleen, stomach, invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain,
The effect of coordinating the drug actions of a prescription.
The honeysuckle detoxicating capsule of the present invention is to be longer than clearing heat and detoxicating honeysuckle dried cream powder as monarch, with field pennycress, mother chrysanthemum
Flower, Fructus Forsythiae, Herba Andrographitis are minister, the clearing heat and detoxicating effect of enhancing, and make the honeysuckle detoxicating capsule of the present invention to virus flu
Fever has preferable therapeutic effect, is made using frankincense, myrrh, windproof, levisticum, radix glycyrrhizae as assistant, frankincense, the myrrh promoting flow of qi and blood circulation, add
The therapeutic effect of strong the monarch and his subjects, windproof and levisticum regulating the function of the liver and spleen, radix glycyrrhizae mediation property of medicine, reduction the monarch and his subjects are strong, and whole formula is rationally matched somebody with somebody
5, there is the effect of very high to clearing heat and detoxicating and treatment flu, and pharmacological property relaxes, and is easily absorbed by the human body.
The beneficial effects of the present invention are：1st, the present invention uses a kind of new dynamic vacuum low-temperature extraction method, ensures anti-
The extraction of bacterium active ingredient is complete, improves pharmaceutical effectiveness and medicinal material utilization rate, and influence factor is inquired into, to test into
Row optimization, finally extracting obtained honeysuckle dried cream powder has higher chlorogenic acid content, and extracting method is easy and effective, easily
In popularization；2nd, it is 3%-5% that honeysuckle dried cream powder produced by the present invention detects green source content through pharmacopeia；3rd, honeysuckle of the invention
Detoxicating capsule is to be longer than clearing heat and detoxicating honeysuckle dried cream powder as monarch, using field pennycress, wild chrysanthemum, Fructus Forsythiae, Herba Andrographitis as minister, enhancing
Clearing heat and detoxicating effect, and make the honeysuckle detoxicating capsule of the present invention that there is preferable therapeutic effect to virus flu fever,
Made using frankincense, myrrh, windproof, levisticum, radix glycyrrhizae as assistant, frankincense, the myrrh promoting flow of qi and blood circulation, strengthen the therapeutic effect of the monarch and his subjects, it is windproof and
Levisticum regulating the function of the liver and spleen, radix glycyrrhizae mediation property of medicine, reduction the monarch and his subjects are strong, are entirely formulated reasonable compatibility, catch a cold to clearing heat and detoxicating and treatment
There is the effect of very high, and pharmacological property relaxes, and is easily absorbed by the human body；4th, the preparation method of honeysuckle detoxicating capsule of the invention is simple
Efficiently, it is easy to industrial production.
Embodiment
For the ease of the understanding of those skilled in the art, with reference to embodiment, the present invention is further illustrated, real
The content that the mode of applying refers to not is limitation of the invention.
Embodiment 1
A kind of honeysuckle extracting method, it is characterised in that：Include the following steps：
(1) once decoct：Honeysuckle is added into the water of 10 times of weight of honeysuckle, an immersion liquid is obtained, to one
Secondary immersion liquid is vacuumized, and being heated to 70 DEG C makes an immersion liquid seethe with excitement, and after keeping the temperature 2h, is filtered, obtains first-time filtrate and filter
Slag；
(2) secondary decoction：The filter residue that step (1) obtains is added into the water of 8 times of weight of filter residue, obtains secondary leaching
Liquid, vacuumizes secondary immersion liquid, and being heated to 70 DEG C makes secondary immersion liquid seethe with excitement, and after keeping the temperature 2h, is filtered, obtains secondary filter
Liquid；
(3) it is concentrated under reduced pressure：After the secondary filtrate that the first-time filtrate and step (2) that step (1) is obtained obtain merges,
It is concentrated under reduced pressure, obtains the medicinal extract that relative density is 1.25；
(4) it is dried in vacuo：The medicinal extract that step (3) obtains is dried in vacuo, that is, obtains honeysuckle dried cream powder.
Wherein, in the step (1) and step (2), the precision of filtering is 100 mesh.
Wherein, during the step (3) is concentrated under reduced pressure, it is 75 DEG C to control the filtrate temperature after merging, and controls what is be concentrated under reduced pressure
Air pressure is -0.06MPa.
The chlorogenic acid content of the honeysuckle dried cream powder is 4.5wt%.
Embodiment 2
A kind of honeysuckle extracting method, it is characterised in that：Include the following steps：
(1) once decoct：Honeysuckle is added into the water of 8 times of weight of honeysuckle, an immersion liquid is obtained, to once
Immersion liquid is vacuumized, and being heated to 60 DEG C makes an immersion liquid seethe with excitement, and after keeping the temperature 1h, is filtered, obtains first-time filtrate and filter residue；
(2) secondary decoction：The filter residue that step (1) obtains is added into the water of 7 times of weight of filter residue, obtains secondary leaching
Liquid, vacuumizes secondary immersion liquid, and being heated to 60 DEG C makes secondary immersion liquid seethe with excitement, and after keeping the temperature 1h, is filtered, obtains secondary filter
Liquid；
(3) it is concentrated under reduced pressure：After the secondary filtrate that the first-time filtrate and step (2) that step (1) is obtained obtain merges,
It is concentrated under reduced pressure, obtains the medicinal extract that relative density is 1.20；
(4) it is dried in vacuo：The medicinal extract that step (3) obtains is dried in vacuo, that is, obtains honeysuckle dried cream powder.
Wherein, in the step (1) and step (2), the precision of filtering is 80 mesh.
Wherein, during the step (3) is concentrated under reduced pressure, it is 65 DEG C to control the filtrate temperature after merging, and controls what is be concentrated under reduced pressure
Air pressure is -0.08MPa.
The chlorogenic acid content of the honeysuckle dried cream powder is 3wt%.
Embodiment 3
A kind of honeysuckle extracting method, it is characterised in that：Include the following steps：
(1) once decoct：Honeysuckle is added into the water of 12 times of weight of honeysuckle, an immersion liquid is obtained, to one
Secondary immersion liquid is vacuumized, and being heated to 80 DEG C makes an immersion liquid seethe with excitement, and after keeping the temperature 3h, is filtered, obtains first-time filtrate and filter
Slag；
(2) secondary decoction：The filter residue that step (1) obtains is added into the water of 9 times of weight of filter residue, obtains secondary leaching
Liquid, vacuumizes secondary immersion liquid, and being heated to 80 DEG C makes secondary immersion liquid seethe with excitement, and after keeping the temperature 3h, is filtered, obtains secondary filter
Liquid；
(3) it is concentrated under reduced pressure：After the secondary filtrate that the first-time filtrate and step (2) that step (1) is obtained obtain merges,
It is concentrated under reduced pressure, obtains the medicinal extract that relative density is 1.30；
(4) it is dried in vacuo：The medicinal extract that step (3) obtains is dried in vacuo, that is, obtains honeysuckle dried cream powder.
Wherein, in the step (1) and step (2), the precision of filtering is 120 mesh.
Wherein, during the step (3) is concentrated under reduced pressure, it is 85 DEG C to control the filtrate temperature after merging, and controls what is be concentrated under reduced pressure
Air pressure is -0.03MPa.
The chlorogenic acid content of the honeysuckle dried cream powder is 5wt%.
Embodiment 4
A kind of honeysuckle extracting method, it is characterised in that：Include the following steps：
(1) once decoct：Honeysuckle is added into the water of 11 times of weight of honeysuckle, an immersion liquid is obtained, to one
Secondary immersion liquid is vacuumized, be heated to 75 DEG C make an immersion liquid seethe with excitement, keep the temperature 1.5h after, filtered, obtain first-time filtrate and
Filter residue；
(2) secondary decoction：The filter residue that step (1) obtains is added into the water of 8 times of weight of filter residue, obtains secondary leaching
Liquid, vacuumizes secondary immersion liquid, and being heated to 65 DEG C makes secondary immersion liquid seethe with excitement, and after keeping the temperature 2.5h, is filtered, obtained secondary
Filtrate；
(3) it is concentrated under reduced pressure：After the secondary filtrate that the first-time filtrate and step (2) that step (1) is obtained obtain merges,
It is concentrated under reduced pressure, obtains the medicinal extract that relative density is 1.27；
(4) it is dried in vacuo：The medicinal extract that step (3) obtains is dried in vacuo, that is, obtains honeysuckle dried cream powder.
Wherein, in the step (1) and step (2), the precision of filtering is 110 mesh.
Wherein, during the step (3) is concentrated under reduced pressure, it is 65-85 DEG C to control the filtrate temperature after merging, and control is concentrated under reduced pressure
Air pressure be -0.04MPa.
The chlorogenic acid content of the honeysuckle dried cream powder is 3.8wt%.
Embodiment 5
A kind of honeysuckle detoxicating capsule, including capsule and the removing toxic substances composition being installed in capsule, the removing toxic substances composition
It is made of the raw material of following parts by weight：
Wherein, the preparation method of the honeysuckle detoxicating capsule is：The raw material removed outside honeysuckle dried cream powder is crushed,
It is fitted into after being mixed with honeysuckle dried cream powder in capsule, that is, obtains the honeysuckle detoxicating capsule.
Wherein, the honeysuckle dried cream powder is honeysuckle dried cream powder made from embodiment 1.
Embodiment 6
A kind of honeysuckle detoxicating capsule, including capsule and the removing toxic substances composition being installed in capsule, the removing toxic substances composition
It is made of the raw material of following parts by weight：
Wherein, the preparation method of the honeysuckle detoxicating capsule is：The raw material removed outside honeysuckle dried cream powder is crushed,
It is fitted into after being mixed with honeysuckle dried cream powder in capsule, that is, obtains the honeysuckle detoxicating capsule.
Wherein, the honeysuckle dried cream powder is honeysuckle dried cream powder made from embodiment 1.
Embodiment 7
A kind of honeysuckle detoxicating capsule, including capsule and the removing toxic substances composition being installed in capsule, the removing toxic substances composition
It is made of the raw material of following parts by weight：
Wherein, the preparation method of the honeysuckle detoxicating capsule is：The raw material removed outside honeysuckle dried cream powder is crushed,
It is fitted into after being mixed with honeysuckle dried cream powder in capsule, that is, obtains the honeysuckle detoxicating capsule.
Wherein, the honeysuckle dried cream powder is honeysuckle dried cream powder made from embodiment 1.
Embodiment 8
A kind of honeysuckle detoxicating capsule, including capsule and the removing toxic substances composition being installed in capsule, the removing toxic substances composition
It is made of the raw material of following parts by weight：
Wherein, the preparation method of the honeysuckle detoxicating capsule is：The raw material removed outside honeysuckle dried cream powder is crushed,
It is fitted into after being mixed with honeysuckle dried cream powder in capsule, that is, obtains the honeysuckle detoxicating capsule.
Wherein, the honeysuckle dried cream powder is honeysuckle dried cream powder made from embodiment 1.
The anxious poison experiment of embodiment 9
Take 4 groups of mouse, every group 10, weight is in 20 ± 2g, each 5 of male and female, when fasting 5 is small, the removing toxic substances group of Example 5
Compound, respectively to every group of intragastric administration on mice, observes mouse active situation, 24 is interior when small by 0g/Kg, 20g/Kg, 80g/Kg, 160g/Kg
Observation 4 times, observation 2 times daily later, to 7 days, find mouse administration group and blank group in action, nervous system reaction and autonomous
Behavioral system reacts no significant difference, LED50It is zero.
10 clinical test of embodiment
Take 5 groups of virus flu patient, every group 30, every group of difference Application Example 5-8 and control capsule for clearing away heat
Treated, wherein the removing toxic substances composition of every capsule of embodiment 4-8 is 0.3g, and control capsule for clearing away heat is commercially available routine
Yinqiaojiedu Capsules.Each patient per takes 3, and 1-3 times daily, treatment is cured to be effective for 1 day, and treatment is controlled for 2-3 days
More be it is effective, treatment 3 days with top cure or do not cure to be invalid, treatment results are as follows：
| Effective/example | Effectively/example | Invalid/example | |
| Embodiment 5 | 16 (53.3%) | 11 (36.7%) | 3 (10%) |
| Embodiment 6 | 15 (50%) | 12 (40%) | 3 (10%) |
| Embodiment 7 | 14 (46.7%) | 12 (40%) | 4 (13.3%) |
| Embodiment 8 | 14 (46.7%) | 12 (40%) | 4 (13.3%) |
| Control | 10 (33.3%) | 14 (46.7%) | 6 (20%) |
As it can be seen that the honeysuckle detoxicating capsule of the present invention, when treating virus flu, into efficient, effect speed is fast, right
Human body has no toxic side effect, cure mainly it is clearing heat and detoxicating, available for anemopyretic cold finding body heat, distending pain in the head, red swelling and pain of throat, cough,
The diseases such as nasal obstruction stream turbid nasal discharge.
Above-described embodiment is the preferable implementation of the present invention, and in addition, the present invention can be realized with other manner,
Do not depart from and any on the premise of present inventive concept obviously replace within protection scope of the present invention.
Claims (10)
- A kind of 1. honeysuckle extracting method, it is characterised in that：Include the following steps：(1) once decoct：Honeysuckle is added into the water of the honeysuckle 8-12 times of weight, an immersion liquid is obtained, to once Immersion liquid is vacuumized, be heated to 60-80 DEG C make an immersion liquid seethe with excitement, keep the temperature 1-3h after, filtered, obtain first-time filtrate and Filter residue；(2) secondary decoction：The filter residue that step (1) obtains is added into the water of the filter residue 7-9 times of weight, obtains secondary leaching Liquid, vacuumizes secondary immersion liquid, and being heated to 60-80 DEG C makes secondary immersion liquid seethe with excitement, and after keeping the temperature 1-3h, is filtered, obtained Secondary filtrate；(3) it is concentrated under reduced pressure：After the secondary filtrate that the first-time filtrate and step (2) that step (1) is obtained obtain merges, carry out It is concentrated under reduced pressure, obtains the medicinal extract that relative density is 1.20-1.30；(4) it is dried in vacuo：The medicinal extract that step (3) obtains is dried in vacuo, that is, obtains honeysuckle dried cream powder.
- A kind of 2. honeysuckle extracting method according to claim 1, it is characterised in that：During the step (1) once decocts, Honeysuckle is added into the water of 10 times of weight of honeysuckle, an immersion liquid is obtained, an immersion liquid is vacuumized, is heated An immersion liquid is seethed with excitement to 60-80 DEG C, after keeping the temperature 2h, filtered, obtain first-time filtrate and filter residue.
- A kind of 3. honeysuckle extracting method according to claim 1, it is characterised in that：In the secondary decoction of the step (2), The filter residue that step (1) obtains is added into the water of 8 times of weight of filter residue, secondary immersion liquid is obtained, secondary immersion liquid is taken out Vacuum, being heated to 60-80 DEG C makes secondary immersion liquid seethe with excitement, and after keeping the temperature 2h, is filtered, obtains secondary filtrate.
- A kind of 4. honeysuckle extracting method according to claim 1, it is characterised in that：The step (1) and step (2) In, the precision of filtering is 80-120 mesh.
- A kind of 5. honeysuckle extracting method according to claim 1, it is characterised in that：During the step (3) is concentrated under reduced pressure, It is 65-85 DEG C to control the filtrate temperature after merging, and it is -0.08MPa~-0.03MPa to control the air pressure being concentrated under reduced pressure.
- A kind of 6. honeysuckle extracting method according to claim 1, it is characterised in that：In step (4) vacuum drying, Vacuum drying mode is vacuum belt type drying, and the temperature of vacuum belt type drying process control medicinal extract is 40-80 DEG C.
- A kind of 7. honeysuckle dried cream powder, it is characterised in that：As the honeysuckle extracting method system described in claim 1-6 any one , the chlorogenic acid content of the honeysuckle dried cream powder is not less than 3wt%.
- A kind of 8. honeysuckle detoxicating capsule, it is characterised in that：Including capsule and the removing toxic substances composition being installed in capsule, the solution Malicious composition includes the raw material of following parts by weight：Wherein, the honeysuckle dried cream powder is the honeysuckle dried cream powder described in claim 7.
- A kind of 9. honeysuckle detoxicating capsule according to claim 8, it is characterised in that：It is described removing toxic substances composition further include as The raw material of lower parts by weight：
- A kind of 10. preparation method of honeysuckle detoxicating capsule described in claim 8 or 9, it is characterised in that：Honeysuckle is removed to do Raw material outside cream powder is crushed, and is fitted into after being mixed with honeysuckle dried cream powder in capsule, that is, obtains the honeysuckle removing toxic substances Capsule.
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