CN108013881B - 用于校正光学信号的方法和装置 - Google Patents

用于校正光学信号的方法和装置 Download PDF

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Publication number
CN108013881B
CN108013881B CN201711281206.6A CN201711281206A CN108013881B CN 108013881 B CN108013881 B CN 108013881B CN 201711281206 A CN201711281206 A CN 201711281206A CN 108013881 B CN108013881 B CN 108013881B
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optical signal
tissue
implant
optical
wavelength range
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Chinese (zh)
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CN108013881A (zh
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G·J·肯兹
W·麦克米伦
N·维希涅夫斯基
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Profusa Inc
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Profusa Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Signal Processing (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Emergency Medicine (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
CN201711281206.6A 2013-03-14 2014-03-06 用于校正光学信号的方法和装置 Expired - Fee Related CN108013881B (zh)

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US201361785087P 2013-03-14 2013-03-14
US61/785,087 2013-03-14
CN201480016308.3A CN105120750B (zh) 2013-03-14 2014-03-06 用于校正光学信号的方法和装置

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CN108013881A CN108013881A (zh) 2018-05-11
CN108013881B true CN108013881B (zh) 2021-06-15

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CN201480016308.3A Expired - Fee Related CN105120750B (zh) 2013-03-14 2014-03-06 用于校正光学信号的方法和装置
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US (4) US10045722B2 (enExample)
EP (2) EP3763292A1 (enExample)
JP (3) JP6457998B2 (enExample)
CN (3) CN108013881B (enExample)
AU (2) AU2014241420B2 (enExample)
BR (1) BR112015022216A2 (enExample)
CA (1) CA2904031A1 (enExample)
WO (1) WO2014158988A1 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9517023B2 (en) 2009-06-01 2016-12-13 Profusa, Inc. Method and system for directing a localized biological response to an implant
US10463287B2 (en) 2010-10-06 2019-11-05 Profusa, Inc. Tissue-integrating sensors
US10010272B2 (en) 2010-05-27 2018-07-03 Profusa, Inc. Tissue-integrating electronic apparatus
US10413251B2 (en) * 2012-10-07 2019-09-17 Rhythm Diagnostic Systems, Inc. Wearable cardiac monitor
USD850626S1 (en) 2013-03-15 2019-06-04 Rhythm Diagnostic Systems, Inc. Health monitoring apparatuses
US10610159B2 (en) * 2012-10-07 2020-04-07 Rhythm Diagnostic Systems, Inc. Health monitoring systems and methods
US10244949B2 (en) 2012-10-07 2019-04-02 Rhythm Diagnostic Systems, Inc. Health monitoring systems and methods
EP3797798B1 (en) 2013-03-14 2022-09-28 Profusa, Inc. Oxygen sensors
EP3763292A1 (en) 2013-03-14 2021-01-13 Profusa, Inc. Method and device for correcting optical signals
US10219729B2 (en) * 2013-06-06 2019-03-05 Profusa, Inc. Apparatus and methods for detecting optical signals from implanted sensors
AU2015302025B2 (en) * 2014-08-11 2021-08-19 The Regents Of The University Of California Continuous analyte sensor
CA2990873A1 (en) * 2015-06-25 2016-12-29 Profusa, Inc. Transcutaneous reader for use with implantable analyte sensors
CN113786195A (zh) 2015-09-02 2021-12-14 梅特罗诺姆中国Ip控股公司 使用光-酶分析物传感器进行连续健康监测的系统和方法
CN115770016A (zh) * 2016-01-26 2023-03-10 耐克创新有限合伙公司 用于感测肌肉组织中糖原的近红外光谱学技术
TWI756218B (zh) * 2016-04-20 2022-03-01 美商菲歐普提斯公司 用於血氧計裝置之探針蓋子、成套工具及形成成套工具的方法
WO2018051975A1 (ja) * 2016-09-14 2018-03-22 Dynamic Brain Lab合同会社 生体情報測定装置
CN115505280A (zh) 2016-12-21 2022-12-23 普罗菲尤萨股份有限公司 可聚合的近红外染料
WO2018119400A1 (en) 2016-12-22 2018-06-28 Profusa, Inc. System and single-channel luminescent sensor for and method of determining analyte value
SG11201906938WA (en) * 2017-01-30 2019-08-27 Medibeacon Inc Method for non-invasive monitoring of fluorescent tracer agent with diffuse reflection corrections
CN114965401B (zh) * 2017-01-30 2025-08-05 麦迪贝肯有限公司 具有背景分离校正的荧光示踪剂的非入侵性监测方法
US11369292B2 (en) * 2017-02-12 2022-06-28 SeeDevice Inc. Portable apparatus for noninvasively measuring blood glucose level and operating method thereof
WO2018156535A1 (en) 2017-02-21 2018-08-30 Dots Technology Corp. Systems for allergen detection
JP2020515367A (ja) * 2017-03-29 2020-05-28 グラフトウォークス, インコーポレイテッド マルチモード診断を伴うウェアラブルデバイス
EP3638119A4 (en) 2017-06-15 2020-11-25 Senseonics, Incorporated SYSTEM AND METHOD FOR MEASURING A QUANTITY OF BLOOD AND / OR COAGULATION IN A POCKET SURROUNDING AN IMPLANTABLE MEDICAL DEVICE
WO2019006400A1 (en) 2017-06-29 2019-01-03 Profusa, Inc. FABRIC INTEGRATION SENSORS FOR DETECTION OF MULTIPLE ANALYTES
KR102531994B1 (ko) 2017-12-29 2023-05-15 삼성전자주식회사 생체 성분 측정 장치 및 방법
JP7561037B2 (ja) 2018-06-27 2024-10-03 プロフサ,インコーポレイテッド 近赤外線グルコースセンサー
JP2021530341A (ja) 2018-07-16 2021-11-11 ビービーアイ、メディカル、イノベーションズ、リミテッド、ライアビリティー、カンパニーBbi Medical Innovations, Llc かん流および酸素化の測定
US11134851B2 (en) 2018-12-14 2021-10-05 Viavi Solutions Inc. Sensor device
JP2022527042A (ja) 2019-01-25 2022-05-30 アールディーエス 健康モニタリングシステム及び方法
WO2020206062A1 (en) * 2019-04-02 2020-10-08 Shifamed Holdings, Llc Systems and methods for monitoring health conditions
US12055481B2 (en) * 2019-08-01 2024-08-06 Viavi Solutions Inc. Sensor device
US11131584B2 (en) * 2019-08-01 2021-09-28 Viavi Solutions Inc. Sensor device
JP2022546991A (ja) 2019-08-28 2022-11-10 アールディーエス バイタルサイン又は健康モニタリングシステム及び方法
DE102019215951A1 (de) * 2019-10-16 2021-04-22 Robert Bosch Gmbh Verfahren, Computerprogramm, elektronisches Speichermedium und Vorrichtung zum Auswerten von optischen Empfangssignalen
JP6931730B1 (ja) * 2020-04-01 2021-09-08 浜松ホトニクス株式会社 光学測定装置及び光学測定方法
JP2023524469A (ja) 2020-04-29 2023-06-12 アールディーエス バイタルサイン又は健康モニタリングシステム及び方法
US11976965B2 (en) * 2021-05-03 2024-05-07 Artilux, Inc. Optical detector module and a method for operating the same
CA3220256A1 (en) * 2021-05-27 2022-12-01 Andrew Dehennis Detecting and correcting for interference in an analyte monitoring system
CN113476043B (zh) * 2021-07-01 2024-09-24 深圳亿杉医疗科技有限公司 一种非侵入式传感装置及检测方法、检测仪
CN115251853B (zh) * 2022-07-26 2025-04-15 中国科学院深圳先进技术研究院 一种微血管的位置检测方法、装置、系统及存储介质
KR20240059195A (ko) * 2022-10-27 2024-05-07 삼성전자주식회사 분석물 성분 농도 추정 장치 및 방법
CN116831572B (zh) * 2023-06-30 2026-07-03 合肥鲸鱼微电子有限公司 生命体征监测仪及生命体征检测系统
KR102661791B1 (ko) * 2023-10-05 2024-04-30 (주)메디띵스 생리학적 정보 추정 방법 및 시스템

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10212140A1 (de) * 2002-03-19 2003-10-09 Henry Arthur Muglia Blutzuckersensor und Meßverfahren zur Bestimmung des Blutzuckerwerts
CN100998499A (zh) * 2003-10-28 2007-07-18 薇拉莱特公司 使用组织荧光确定某一糖化终产物或疾病状态
CN101917899A (zh) * 2007-11-05 2010-12-15 生物传感器公司 用于测定分析物浓度的光学传感器

Family Cites Families (197)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703756A (en) 1986-05-06 1987-11-03 The Regents Of The University Of California Complete glucose monitoring system with an implantable, telemetered sensor module
US5242835A (en) 1987-11-03 1993-09-07 Radiometer A/S Method and apparatus for determining the concentration of oxygen
US6040194A (en) 1989-12-14 2000-03-21 Sensor Technologies, Inc. Methods and device for detecting and quantifying substances in body fluids
US5342789A (en) 1989-12-14 1994-08-30 Sensor Technologies, Inc. Method and device for detecting and quantifying glucose in body fluids
US5222496A (en) * 1990-02-02 1993-06-29 Angiomedics Ii, Inc. Infrared glucose sensor
US6362175B1 (en) 1991-09-20 2002-03-26 The Trustees Of The University Of Pennsylvania Porphyrin compounds for imaging tissue oxygen
US5284140A (en) 1992-02-11 1994-02-08 Eli Lilly And Company Acrylic copolymer membranes for biosensors
JP2533430B2 (ja) 1992-03-24 1996-09-11 三ツ星ベルト株式会社 色素分子を分散させたポリアミド複合物とその製造方法
IL107396A (en) 1992-11-09 1997-02-18 Boehringer Mannheim Gmbh Method and apparatus for analytical determination of glucose in a biological matrix
US5487885A (en) 1992-12-21 1996-01-30 Biophysica, Inc. Sunblocking polymers and their formulation
US5837865A (en) 1993-10-15 1998-11-17 Trustees Of The University Of Pennsylvania Phosphorescent dendritic macromolecular compounds for imaging tissue oxygen
US5882494A (en) 1995-03-27 1999-03-16 Minimed, Inc. Polyurethane/polyurea compositions containing silicone for biosensor membranes
US5628310A (en) * 1995-05-19 1997-05-13 Joseph R. Lakowicz Method and apparatus to perform trans-cutaneous analyte monitoring
US6104945A (en) 1995-08-01 2000-08-15 Medispectra, Inc. Spectral volume microprobe arrays
US6766183B2 (en) * 1995-11-22 2004-07-20 Medtronic Minimed, Inc. Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers
US5711861A (en) 1995-11-22 1998-01-27 Ward; W. Kenneth Device for monitoring changes in analyte concentration
US6002954A (en) 1995-11-22 1999-12-14 The Regents Of The University Of California Detection of biological molecules using boronate-based chemical amplification and optical sensors
WO1997019188A1 (en) * 1995-11-22 1997-05-29 Minimed, Inc. Detection of biological molecules using chemical amplification and optical sensors
DE59707650D1 (de) 1996-01-26 2002-08-08 Roche Diagnostics Gmbh Verfahren und vorrichtung zur bestimmung eines analyten in einer streuenden matrix
AUPN814496A0 (en) 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
GB9616896D0 (en) 1996-08-12 1996-09-25 British Tech Group Pharmaceutical compositions
WO1998022820A1 (en) 1996-11-21 1998-05-28 Lawrence Livermore National Laboratory Detection of biological molecules using boronate-based chemical amplification and optical sensors
US6274086B1 (en) 1996-12-16 2001-08-14 The Trustees Of The University Of Pennsylvania Apparatus for non-invasive imaging oxygen distribution in multi-dimensions
US6043437A (en) 1996-12-20 2000-03-28 Alfred E. Mann Foundation Alumina insulation for coating implantable components and other microminiature devices
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US6741877B1 (en) 1997-03-04 2004-05-25 Dexcom, Inc. Device and method for determining analyte levels
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US7192450B2 (en) 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US5895658A (en) 1997-09-17 1999-04-20 Fossel; Eric T. Topical delivery of L-arginine to cause tissue warming
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
GB9814506D0 (en) 1998-07-03 1998-09-02 Stanley Christopher J Optical sensor for insitu measurement of analytes
ATE468068T1 (de) 1998-07-04 2010-06-15 Whitland Res Ltd Unblutige messung von analyten aus blut
US6013122A (en) 1998-08-18 2000-01-11 Option Technologies, Inc. Tattoo inks
WO2000010622A1 (en) 1998-08-20 2000-03-02 Cook Incorporated Coated implantable medical device
EP2325622B1 (en) * 1998-08-26 2014-03-12 Sensors for Medicine and Science, Inc. Optical-based sensing device
US6602678B2 (en) 1998-09-04 2003-08-05 Powderject Research Limited Non- or minimally invasive monitoring methods
DE69924749T2 (de) 1998-11-20 2006-04-27 The University Of Connecticut, Farmington Generisch integrierte implantierbare Potentiostatfernmeßanordnung für elektrochemische Fühler
US20030099682A1 (en) 1998-11-20 2003-05-29 Francis Moussy Apparatus and method for control of tissue/implant interactions
US6783937B1 (en) 1999-02-25 2004-08-31 Pall Corporation Negatively charged membrane
US8346363B2 (en) 1999-03-05 2013-01-01 Metacure Limited Blood glucose level control
US6475750B1 (en) 1999-05-11 2002-11-05 M-Biotech, Inc. Glucose biosensor
US6366793B1 (en) 1999-09-10 2002-04-02 Beckman Coulter, Inc. Minimally invasive methods for measuring analtes in vivo
US20050119737A1 (en) 2000-01-12 2005-06-02 Bene Eric A. Ocular implant and methods for making and using same
US6916665B2 (en) 2000-02-11 2005-07-12 The Texas A&M University System Biosensor compositions and methods of use
DE10011284B4 (de) 2000-03-08 2007-06-28 Disetronic Licensing Ag Vorrichtung für eine In-vivo Messung der Konzentration eines Inhaltsstoffs einer Körperflüssigkeit
US20020043651A1 (en) 2000-04-04 2002-04-18 Darrow Christopher B. Fluorescent lifetime assays for non-invasive quantification of analytes such as glucose
US6565960B2 (en) 2000-06-01 2003-05-20 Shriners Hospital Of Children Polymer composite compositions
US20020048577A1 (en) 2000-08-01 2002-04-25 University Of Washington Methods and devices to modulate the wound response
CA2415338C (en) 2000-08-04 2012-10-23 Sensors For Medicine And Science, Inc. Detection of analytes in aqueous environments
GB0025147D0 (en) 2000-10-13 2000-11-29 Torsana Diabetes Diagnostics A Optical sensor for in situ measurement of analytes
US6642015B2 (en) 2000-12-29 2003-11-04 Minimed Inc. Hydrophilic polymeric material for coating biosensors
US8069254B2 (en) 2001-02-28 2011-11-29 Sharp Laboratories Of America, Inc. Communication period management in a communication system
US6694158B2 (en) 2001-04-11 2004-02-17 Motorola, Inc. System using a portable detection device for detection of an analyte through body tissue
US20040152963A1 (en) 2001-04-27 2004-08-05 March Wayne Front Apparatus for measuring blood glucose concentrations
FI20010898A0 (fi) 2001-04-30 2001-04-30 Ylae Herttuala Seppo Ekstrasellulaarinen superoksididismutaasi (EC-SOD) geeniterapia restenoosoin ehkäisemiseksi
WO2002087696A1 (en) 2001-04-30 2002-11-07 Medtronic,Inc. Transcutaneous monitor and method of use, using therapeutic output from an implanted medical device
US6844028B2 (en) 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
GB0116853D0 (en) 2001-07-10 2001-09-05 Torsana Diabetes Diagnostics A Optical sensor containing particles for in SITU measurement of analytes
US6702857B2 (en) 2001-07-27 2004-03-09 Dexcom, Inc. Membrane for use with implantable devices
US7096053B2 (en) 2001-10-02 2006-08-22 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Internal biochemical sensing device
KR100955410B1 (ko) 2001-11-27 2010-05-06 타키론 가부시기가이샤 임플란트 재료 및 이의 제조방법
TWI293363B (en) 2001-12-11 2008-02-11 Sensors For Med & Science Inc High performance fluorescent optical sensor
US7202947B2 (en) * 2001-12-19 2007-04-10 Wisconsin Alumni Research Foundation Depth-resolved fluorescence instrument with angled excitation
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
GB0204640D0 (en) 2002-02-27 2002-04-10 Torsana Diabetes Diagnostics A Injection apparatus
US7153265B2 (en) 2002-04-22 2006-12-26 Medtronic Minimed, Inc. Anti-inflammatory biosensor for reduced biofouling and enhanced sensor performance
US7813780B2 (en) 2005-12-13 2010-10-12 Medtronic Minimed, Inc. Biosensors and methods for making and using them
US20030208166A1 (en) 2002-05-06 2003-11-06 Schwartz Anthony H. Implantable device with free-flowing exit and uses thereof
CN1655738A (zh) 2002-05-20 2005-08-17 奥勃斯医学技术股份有限公司 可植入的药物洗脱医疗装置
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
US20050118726A1 (en) 2002-08-26 2005-06-02 Schultz Jerome S. System and method for detecting bioanalytes and method for producing a bioanalyte sensor
US7285424B2 (en) * 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7162289B2 (en) 2002-09-27 2007-01-09 Medtronic Minimed, Inc. Method and apparatus for enhancing the integrity of an implantable sensor device
US20040106951A1 (en) 2002-11-22 2004-06-03 Edman Carl Frederick Use of electric fields to minimize rejection of implanted devices and materials
US20040143221A1 (en) 2002-12-27 2004-07-22 Shadduck John H. Biomedical implant for sustained agent release
US7811231B2 (en) 2002-12-31 2010-10-12 Abbott Diabetes Care Inc. Continuous glucose monitoring system and methods of use
US20040133079A1 (en) 2003-01-02 2004-07-08 Mazar Scott Thomas System and method for predicting patient health within a patient management system
US20040161853A1 (en) 2003-02-13 2004-08-19 Zhongping Yang Implantable chemical sensor with rugged optical coupler
DE602004007771T2 (de) 2003-02-14 2007-12-06 Eyesense Ag Vorrichtung zur messung der konzentration eines analyten in einer augenflüssigkeit
US7772286B2 (en) 2003-02-28 2010-08-10 Eyesense Ag Polyvinyl alcohol copolymers comprising biomolecules
WO2005016396A1 (en) 2003-08-13 2005-02-24 Poly-Med, Inc. Biocompatible controlled release coatings for medical devices and related methods
US6965791B1 (en) 2003-03-26 2005-11-15 Sorenson Medical, Inc. Implantable biosensor system, apparatus and method
US6828572B2 (en) 2003-04-01 2004-12-07 Axcelis Technologies, Inc. Ion beam incident angle detector for ion implant systems
US7134999B2 (en) 2003-04-04 2006-11-14 Dexcom, Inc. Optimized sensor geometry for an implantable glucose sensor
US20070010702A1 (en) 2003-04-08 2007-01-11 Xingwu Wang Medical device with low magnetic susceptibility
US7186789B2 (en) 2003-06-11 2007-03-06 Advanced Cardiovascular Systems, Inc. Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings
US20040259270A1 (en) * 2003-06-19 2004-12-23 Wolf David E. System, device and method for exciting a sensor and detecting analyte
WO2005015184A1 (en) 2003-07-30 2005-02-17 Novartis Ag Reflection hologram sensor in contact lens
US20050027175A1 (en) 2003-07-31 2005-02-03 Zhongping Yang Implantable biosensor
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
DE602004028020D1 (de) 2003-08-07 2010-08-19 Eyesense Ag Ophthalmischer sensor
EP1670385B1 (en) 2003-10-01 2013-01-23 University of Washington Novel porous biomaterials
US20050095174A1 (en) 2003-10-31 2005-05-05 Wolf David E. Semipermeable sensors for detecting analyte
ATE482650T1 (de) 2003-11-03 2010-10-15 Microchips Inc Medizinprodukt zum messen von glucose
WO2005051170A2 (en) 2003-11-19 2005-06-09 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US20050158356A1 (en) 2003-11-20 2005-07-21 Angiotech International Ag Implantable sensors and implantable pumps and anti-scarring agents
US20050148003A1 (en) 2003-11-26 2005-07-07 Steven Keith Methods of correcting a luminescence value, and methods of determining a corrected analyte concentration
US7496392B2 (en) * 2003-11-26 2009-02-24 Becton, Dickinson And Company Fiber optic device for sensing analytes
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
DE602004029092D1 (de) 2003-12-05 2010-10-21 Dexcom Inc Kalibrationsmethoden für einen kontinuierlich arbeitenden analytsensor
US7146203B2 (en) 2003-12-18 2006-12-05 Elliot Botvinick Implantable biosensor and methods of use thereof
GB0329849D0 (en) 2003-12-23 2004-01-28 Precisense As Fluorometers
US8029765B2 (en) 2003-12-24 2011-10-04 Masimo Laboratories, Inc. SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors
US20060002969A1 (en) 2004-01-27 2006-01-05 University Of Washington Methods for reducing the foreign body reaction
US7450980B2 (en) 2004-03-31 2008-11-11 Terumo Kabushiki Kaisha Intracorporeal substance measuring assembly
EP1737899B1 (en) 2004-04-20 2015-07-08 Dendritic Nanotechnologies, Inc. Dendritic polymers with enhanced amplification and interior functionality
US20050245799A1 (en) 2004-05-03 2005-11-03 Dexcom, Inc. Implantable analyte sensor
CN101087630A (zh) 2004-05-04 2007-12-12 罗切斯特大学 可植入生物电生理界面基质
US8849416B2 (en) 2004-05-04 2014-09-30 University Of Rochester Implantable bio-electro-physiologic interface matrix
GB0411162D0 (en) * 2004-05-19 2004-06-23 Precisense As Optical sensor for in vivo detection of analyte
US8690865B2 (en) 2004-05-28 2014-04-08 Georgia Tech Research Corporation Methods and devices for thermal treatment
AU2004320509A1 (en) 2004-06-02 2005-12-22 Darrel Dean Drinan Use of electric fields to minimize rejection of implanted devices and materials
WO2005120334A1 (en) 2004-06-14 2005-12-22 Eyesense Ag Combined apparatus for measuring the blood glucose level from an ocular fluid
US20070004046A1 (en) 2005-07-01 2007-01-04 Platypus Technologies, Llc Detection of analytes
US7968085B2 (en) 2004-07-05 2011-06-28 Ascendis Pharma A/S Hydrogel formulations
GB0416732D0 (en) 2004-07-27 2004-09-01 Precisense As A method and apparatus for measuring the phase shift induced in a light signal by a sample
CA2578227A1 (en) 2004-08-24 2006-11-30 University Of South Florida Epoxy enhanced polymer membrane to increase durability of biosensors
US7166680B2 (en) 2004-10-06 2007-01-23 Advanced Cardiovascular Systems, Inc. Blends of poly(ester amide) polymers
US7248907B2 (en) * 2004-10-23 2007-07-24 Hogan Josh N Correlation of concurrent non-invasively acquired signals
GB0426822D0 (en) 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
WO2006105146A2 (en) 2005-03-29 2006-10-05 Arkal Medical, Inc. Devices, systems, methods and tools for continuous glucose monitoring
US20060270919A1 (en) * 2005-05-11 2006-11-30 Mytek, Llc Biomarkers sensing
JP2008541881A (ja) 2005-05-27 2008-11-27 ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド ウィルス性疾患用の孤立パッチ
US20070038046A1 (en) * 2005-08-09 2007-02-15 Hayter Paul G Kinematic fluorescence measurement band
US7725148B2 (en) 2005-09-23 2010-05-25 Medtronic Minimed, Inc. Sensor with layered electrodes
US7704704B2 (en) 2005-09-28 2010-04-27 The Texas A&M University System Implantable system for glucose monitoring using fluorescence quenching
US8515518B2 (en) 2005-12-28 2013-08-20 Abbott Diabetes Care Inc. Analyte monitoring
US8160670B2 (en) 2005-12-28 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring: stabilizer for subcutaneous glucose sensor with incorporated antiglycolytic agent
US8114269B2 (en) 2005-12-30 2012-02-14 Medtronic Minimed, Inc. System and method for determining the point of hydration and proper time to apply potential to a glucose sensor
EP2004241B1 (en) 2006-03-28 2013-08-07 Glusense Ltd. Implantable sensor
US8126554B2 (en) 2006-05-17 2012-02-28 Cardiac Pacemakers, Inc. Implantable medical device with chemical sensor and related methods
CN101505723A (zh) 2006-06-22 2009-08-12 南佛罗里达大学 胶原支架、具有其的医用植入物以及使用方法
ES2314793T3 (es) 2006-07-24 2009-03-16 Eyesense Ag Dispositivo para medir un analito en un fluido ocular.
US8326389B2 (en) 2006-12-07 2012-12-04 The Ohio State University Research Foundation System for in vivo biosensing based on the optical response of electronic polymers
US20080139903A1 (en) 2006-12-08 2008-06-12 Isense Corporation Method and apparatus for insertion of a sensor using an introducer
DE102007003341B4 (de) 2007-01-17 2018-01-04 Eyesense Ag Okularsensor und Messsystem zum Nachweis eines Analyten in einer Augenflüssigkeit
CN105826345B (zh) 2007-01-17 2018-07-31 伊利诺伊大学评议会 通过基于印刷的组装制造的光学系统
US8088097B2 (en) 2007-11-21 2012-01-03 Glumetrics, Inc. Use of an equilibrium intravascular sensor to achieve tight glycemic control
EP2162057A1 (en) 2007-05-10 2010-03-17 Glumetrics, Inc. Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement
DE102007024642A1 (de) 2007-05-24 2008-11-27 Eyesense Ag Hydrogel-Implantat für Sensorik von Metaboliten am Auge
US8562558B2 (en) 2007-06-08 2013-10-22 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US8785624B2 (en) 2007-06-13 2014-07-22 University Of Southern California Organic photosensitive optoelectronic devices with nonplanar porphyrins
GB0717150D0 (en) 2007-09-04 2007-10-17 Univ Warwick Apparatus and method
GB0803492D0 (en) 2008-02-26 2008-04-02 Glysure Ltd Fibre optic sensor
US8080821B2 (en) 2008-03-18 2011-12-20 The University Of Connecticut Thyristor radiation detector array and applications thereof
US8452402B2 (en) 2008-04-23 2013-05-28 Medtronic, Inc. Optical sensing device for use in a medical device
US8986208B2 (en) 2008-09-30 2015-03-24 Abbott Diabetes Care Inc. Analyte sensor sensitivity attenuation mitigation
ATE507768T1 (de) 2008-10-02 2011-05-15 Eyesense Ag Implantationsvorrichtung für metabolitsensoren
ES2530450T3 (es) 2008-10-02 2015-03-03 Eyesense Ag Elemento sensor implantable
CA2683467C (en) 2008-10-24 2016-01-26 Jin Zhang Contact lens integrated with a biosensor for detection of glucose and other components in tears
US20100160749A1 (en) 2008-12-24 2010-06-24 Glusense Ltd. Implantable optical glucose sensing
EP2424426B1 (en) 2009-04-29 2020-01-08 Abbott Diabetes Care, Inc. Method and system for providing data communication in continuous glucose monitoring and management system
ES2571135T3 (es) 2009-05-18 2016-05-24 Lightship Medical Ltd Método de calibración de sensor de glucosa
US9517023B2 (en) * 2009-06-01 2016-12-13 Profusa, Inc. Method and system for directing a localized biological response to an implant
US20110028806A1 (en) 2009-07-29 2011-02-03 Sean Merritt Reflectance calibration of fluorescence-based glucose measurements
EP2314608A1 (de) 2009-10-26 2011-04-27 EyeSense AG Stabilisierung von Biosensoren für in vivo Anwendungen
WO2011101627A2 (en) 2010-02-19 2011-08-25 Glysure Ltd Fluorescence measurement
US20130072768A1 (en) 2010-02-19 2013-03-21 Barry Colin Crane Intravascular glucose sensor
CA2790198A1 (en) * 2010-02-19 2011-08-25 Lightship Medical Limited Subcutaneous glucose sensor
US8579879B2 (en) 2010-02-19 2013-11-12 Medtronic Minimed, Inc. Closed-loop glucose control startup
JP2013519894A (ja) 2010-02-19 2013-05-30 ライトシップ メディカル リミテッド 光ファイバーセンサ用の指示システム
EP2974673B1 (en) 2010-03-17 2017-03-22 The Board of Trustees of the University of Illionis Implantable biomedical devices on bioresorbable substrates
FR2958557B1 (fr) 2010-04-07 2014-10-31 Centre Nat Rech Scient Procede de traitement d'effluents comprenant des composes halogenes
KR101813300B1 (ko) 2010-04-08 2017-12-28 힐리오닉스 코포레이션 미세다공성 표면 층을 가지는 이식형 의료 장치 및 이에 대한 이물 반응을 감소시키는 방법
US10463287B2 (en) 2010-10-06 2019-11-05 Profusa, Inc. Tissue-integrating sensors
US10010272B2 (en) 2010-05-27 2018-07-03 Profusa, Inc. Tissue-integrating electronic apparatus
US8543354B2 (en) 2010-06-23 2013-09-24 Medtronic Minimed, Inc. Glucose sensor signal stability analysis
US9515206B2 (en) 2010-08-25 2016-12-06 The University Of South Dakota Electron-deficient fluorous porphyrins and methods of making and their use in organic solar cells
US20120123276A1 (en) 2010-11-16 2012-05-17 Assaf Govari Catheter with optical contact sensing
US9167138B2 (en) 2010-12-06 2015-10-20 Apple Inc. Pattern projection and imaging using lens arrays
AU2011344290B2 (en) 2010-12-17 2016-02-25 Eyesense Ag Competitive biosensor having elevated sensitivity
ES2593458T3 (es) 2010-12-17 2016-12-09 Eyesense Ag Uso de hidrogeles para biosensores con sensibilidad elevada
CA2823515C (en) 2010-12-28 2019-06-04 Dura Chemicals, Inc. Additives for curable liquid compositions
US20120172692A1 (en) 2011-01-05 2012-07-05 Janet Tamada Sensing Fluid Concentration for Continuous Glucose Monitoring
US20120245445A1 (en) 2011-03-21 2012-09-27 Michael Darryl Black Glucose Monitoring System
US9008744B2 (en) 2011-05-06 2015-04-14 Medtronic Minimed, Inc. Method and apparatus for continuous analyte monitoring
US9037205B2 (en) 2011-06-30 2015-05-19 Glusense, Ltd Implantable optical glucose sensing
CN103547642B (zh) 2011-07-01 2015-12-02 英派尔科技开发有限公司 用于保存纤维素材料的对羟基苯甲酸酯衍生物
WO2013025801A2 (en) 2011-08-15 2013-02-21 University Of Connecticut Control of biofouling in implantable biosensors
US20130060106A1 (en) 2011-09-06 2013-03-07 Medtronic Minimed, Inc. Optical sensing systems and methods
JP2013103094A (ja) 2011-11-16 2013-05-30 Sony Corp 測定装置、測定方法、プログラム及び記録媒体
US20130158413A1 (en) * 2011-12-15 2013-06-20 Nellcor Puritan Bennett Llc Optical measurement of physiological blood parameters
WO2013102162A1 (en) 2011-12-29 2013-07-04 Wellsense, Inc. Analyte sensor with extended range of detection
US8891088B2 (en) * 2012-01-20 2014-11-18 The Curators Of The University Of Missouri Total internal reflection photoacoustic spectroscopy
DE102012201892A1 (de) 2012-02-09 2013-08-14 Robert Bosch Gmbh Bestimmung des Blutzuckerspiegels eines Patienten unter Verwendung eines implantierbaren Sensors und eines elektrischen Funktionspflasters
US9693714B2 (en) * 2012-02-10 2017-07-04 Senseonics, Incorporated Digital ASIC sensor platform
US8869588B2 (en) 2012-02-21 2014-10-28 Symbol Technologies, Inc. Ultrasonic positioning system with reverberation and flight time compensation
WO2013132400A1 (en) * 2012-03-08 2013-09-12 Koninklijke Philips N.V. Apparatus for determining a property of a tissue
US9493807B2 (en) 2012-05-25 2016-11-15 Medtronic Minimed, Inc. Foldover sensors and methods for making and using them
EP3797798B1 (en) 2013-03-14 2022-09-28 Profusa, Inc. Oxygen sensors
EP3763292A1 (en) 2013-03-14 2021-01-13 Profusa, Inc. Method and device for correcting optical signals
US10219729B2 (en) 2013-06-06 2019-03-05 Profusa, Inc. Apparatus and methods for detecting optical signals from implanted sensors
CA2990873A1 (en) 2015-06-25 2016-12-29 Profusa, Inc. Transcutaneous reader for use with implantable analyte sensors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10212140A1 (de) * 2002-03-19 2003-10-09 Henry Arthur Muglia Blutzuckersensor und Meßverfahren zur Bestimmung des Blutzuckerwerts
CN100998499A (zh) * 2003-10-28 2007-07-18 薇拉莱特公司 使用组织荧光确定某一糖化终产物或疾病状态
CN101917899A (zh) * 2007-11-05 2010-12-15 生物传感器公司 用于测定分析物浓度的光学传感器

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