CN107998046B - A kind of scalp care compositions and preparation method thereof - Google Patents
A kind of scalp care compositions and preparation method thereof Download PDFInfo
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- CN107998046B CN107998046B CN201711411139.5A CN201711411139A CN107998046B CN 107998046 B CN107998046 B CN 107998046B CN 201711411139 A CN201711411139 A CN 201711411139A CN 107998046 B CN107998046 B CN 107998046B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
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- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a kind of scalp care compositions and preparation method thereof, scalp care compositions of the present invention include macromolecule moisturizer, small molecule moisturizer, phytosterol, camellia oil, white pond flower seed oil, isohexadecane, ceramide -1, hydrolecithin, rosemary leaf extract, vegetable active extract, EDTA-2Na, rosemary leaf extract, Pidolidone and water, scalp care compositions each component content proportion of the present invention is reasonable, the scalp care compositions for being prepared into the present invention are mild, clearly, it moistens, it can effectively alleviate that scalp is dry to itch, the problems such as allergy and related inflammation, increase the barrier function of skin.
Description
Technical field
The present invention relates to cosmetic composition technical field more particularly to a kind of scalp care compositions and its preparation sides
Method.
Background technique
For scalp care product based on shampoo, people are still relatively thin to the nursing idea of scalp currently on the market.
Although scalp and hair that shampoo can clean us make its cleaning, the protectiveness on our scalps has also been washed away simultaneously
Sebum.The skin barrier of even scalp can also be destroyed during cleaning and scratching and grab sometimes.In recent years, in the market without
Silicone oil shampoo is popular, it is intended to replace conventional table living and silicone oil with mild table grease living and moist, be reached with this
Protect the purpose of scalp.But effect is very unsatisfactory, and even if having added moistness grease, because the grease residence time is short, final quilt
It washes away, scalp is more dry.Drying will be with the dry and astringent peeling of itching of the scalp, and the increasing without silicone oil shampoo hair conditioning
Adding, is more by means of a large amount of cation opsonizing agent, these cation opsonizing agents may bring certain stimulation to scalp,
And then make itching of the scalp.The itch and dry scalp of scalp destroy the barrier function of skin of head gradually, and scalp is sensitive
The problem of it is increasingly severe.Scalp is the soil for breeding and nourishing hair, and scalp is unhealthy will directly or indirectly to influence hair
State, especially the user of allergic constitution is for the more demanding of scalp care product.
Meanwhile in current other types cosmetics for skin, although moisturizer is frequently applied, existing research discovery,
The type of moisturizer addition, concentration and effect can be all influenced with the ratios of other greases or even ratio mistake can allow original instead
There are the moisture-keeping functions of skin to decline.Therefore, needing to develop a kind of makes that scalp is moist, antipruritic and antiallergic, salubrious component are taken simultaneously
With reasonable scalp care product.
Summary of the invention
The purpose of this section is to summarize some aspects of the embodiment of the present invention and briefly introduce some preferable implementations
Example.It may do a little simplified or be omitted to avoid our department is made in this section and the description of the application and the title of the invention
Point, the purpose of abstract of description and denomination of invention it is fuzzy, and this simplification or omit and cannot be used for limiting the scope of the invention.
In view of above-mentioned existing scalp care product there are the problem of, propose the present invention.
Therefore, the one of purpose of the present invention is to overcome the shortcomings of existing scalp care product, provides a kind of scalp care
Composition.
In order to solve the above technical problems, according to an aspect of the present invention, the invention provides the following technical scheme: a kind of head
Skin care composition, includes, macromolecule moisturizer, small molecule moisturizer, phytosterol, camellia oil, white pond flower seed oil, and different 16
Alkane, ceramide -1, hydrolecithin, rosemary leaf extract, vegetable active extract, EDTA-2Na, rosemary leave are extracted
Object, Pidolidone and water, wherein
By percentage to the quality, macromolecule content of humectant 0.01~1%, small molecule content of humectant 2~10%, plant
Sterol content 0~5%, camellia oil content 0~5%, white pond flower seed oil content 0~5%, isohexadecane content 2~8%, nerve
- 1 content 0.1~2% of amide, hydrolecithin content 0~2%, rosemary leaf extract content 0.1~0.5%, vegetable active
Extractive content 2~30%, EDTA-2Na content 0.01~0.1%, rosemary leaf extract content 0.1~0.5%, L- paddy ammonia
Acid, remainder are water.
A kind of preferred embodiment as scalp care compositions of the present invention, wherein the scalp care compositions
For nanoemulsions spray composite.
A kind of preferred embodiment as scalp care compositions of the present invention, wherein the macromolecule moisturizer packet
Include Sodium Hyaluronate, one of tremella polysaccharides or gamma-polyglutamic acid sodium or a variety of.
A kind of preferred embodiment as scalp care compositions of the present invention, wherein the Sodium Hyaluronate and institute
The mass percent for stating tremella polysaccharides is 1:1.
A kind of preferred embodiment as scalp care compositions of the present invention, wherein the small molecule moisturizer packet
Include glycerol, butanediol, antierythrite, hexylene glycol, pentanediol, 1,3-PD, glycine betaine, panthenol, serine, in arginine
It is one or more.
A kind of preferred embodiment as scalp care compositions of the present invention, wherein the vegetable active extract
Including oat extract, common cnidium fruit P.E, blue gum leaf extract, Cacumen Platycladi extract, Baical Skullcap root P.E, peony root extractive
One of or it is a variety of.
A kind of preferred embodiment as scalp care compositions of the present invention, wherein the scalp care compositions
Component be respectively as follows: by percentage to the quality EDTA-2Na content be 0.05%, hexylene glycol content be 2%, glycerol glycerol content
It is 4%, hyaluronic acid sodium content is 0.05%, and tremella polysaccharides content is 0.05%, and panthenol content is 0.5%, serine content
It is 0.2%, arginine content 0.1%, beet alkali content 1%, erythrose alcohol content is 1%, and white pond flower seed oil content is
4%, content of phytosterol 1%, seed of Flos Camelliae Japonicae oil content is 2%, and isohexadecane content is 2%, and hydrolecithin content is
1%, jojoba oil content is 2%, and Eucalyptus globulus Labill leaf extractive content is 4%, and Cacumen Platycladi extract content is 5%, and frutus cnidii extracts
Object content is 5%, and oat extract content is 4%, and peony root extractive content is 2%, and radix scutellariae content is 4%, rosemary leave
Extractive content is 0.2%, and Pidolidone is water for adjusting pH value, remainder.
It is a further object of the invention to provide a kind of preparation methods of scalp care compositions.
In order to solve the above technical problems, according to an aspect of the present invention, the invention provides the following technical scheme: preparing head
The method of skin care composition comprising, heating: the water phase of the composition and oil phase component are heated respectively;Homogeneous: by institute
Stating oil phase component and water phase homogenizer homogeneous is added is primary emulsion;
It is cooling: plant extracts will to be added after primary emulsion cooling.
It as a kind of preferred embodiment of the method for the present invention for preparing scalp care compositions, further include preparing
Nanoemulsions: nanoemulsions will be made using gradient homogeneous method through overcooled primary emulsion high pressure homogenizer homogeneous;System
It is standby spraying: the nanoemulsions being dispensed into spray bottle, it is spraying that nanoemulsions are made.
A kind of preferred embodiment as the method for the present invention for preparing scalp care compositions, wherein the heating,
Temperature is 80 DEG C;The homogeneous, speed 3000r/s, time 3min;The cooling is added plant and mentions when being cooled to 50 DEG C
Take object;The gradient homogeneous, successively are as follows: 40MPa homogeneous 5 times;60Mpa homogeneous 5 times;80Mpa homogeneous 5 times.
Beneficial effects of the present invention: the white pond flower seed oil that the present invention selects mutually is cooperateed with rosemary leaf extract, significantly
Promote antioxidant effect;Phytosterol is mutually cooperateed with jojoba oil and vegetable active extract with excellent anti-inflammatory effect;Mountain
Tea flower seed oil mutually cooperates with enhancing skin transdermal enhancing effect with sterol;White pond flower seed oil, seed of Flos Camelliae Japonicae oil and jojoba oil also have simultaneously
Standby moisturizing effect, mutually cooperates with the hydrolecithin as emulsifier and emollient, while keeping skin more a softer and smoother touch
Skin will not be made to feel greasy, the moisture of balance skin has very strong water lock ability, improves the water balance of skin;Nerve
Amide also has stronger skin barrier effect while mutually cooperateing with as sealer with isohexadecane, in moisturizer, profit
Make skin barrier effect reach best, of the invention each component content under the synergistic effect of skin agent and sealer to match rationally, make
The scalp care compositions that the present invention is prepared into are mild, clearly, moisten, can effectively alleviate scalp it is dry itch, allergy and it is related inflammation
The problems such as disease, increases the barrier function of skin.
Nanoemulsions made of scalp care compositions of the invention are spraying so that the alleviation scalp of product of the present invention is done
Itch, moisturizing, salubrious, antiallergy and antiphlogistic effects reach best.
The present invention is using natural anti-oxidation and again being rich in nutrition grease such as phytosterol, camellia caul-fat and Bai Chihua
Seed oil, it is mild not only to make formula, but also can moisten scalp.
The present invention does not add the essence and preservative that may bring stimulation, and it is anti-that anti-corrosion is reached with plant society extract
The effect of bacterium reduces the irritation of skin, improves safety.
Pleasant skin sense is brought while the present invention does not stimulate skin.
Meanwhile the natural plant extracts of this product addition can play anti-no skin irritation while anti-inflammatory
The effect of allergy.
The reasonable combination of reasonable mixture ratio of components of the invention, the selection of each component and constituent mass ratio makes the scalp of this product
Nursing efficacy is extremely significant.
Detailed description of the invention
In order to illustrate the technical solution of the embodiments of the present invention more clearly, required use in being described below to embodiment
Attached drawing be briefly described, it should be apparent that, drawings in the following description are only some embodiments of the invention, for this
For the those of ordinary skill of field, without any creative labor, it can also be obtained according to these attached drawings other
Attached drawing.Wherein:
Fig. 1 changes with time for skin moisture content.
Fig. 2 is to be sprayed the 1st day and the 28th day skin transepidermal water loss value using scalp care nanoemulsions of the present invention.
Fig. 3 is that the dry person that has dandruff of itching of scalp carries out continuing tracking and testing using scalp care nanoemulsions of the present invention by spraying
Effect assessment.
Fig. 4 is the spraying nanoemulsions particle diameter distribution of scalp care nanoemulsions of the present invention.
Specific embodiment
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, right with reference to the accompanying drawings of the specification
A specific embodiment of the invention is described in detail, it is clear that and described embodiment is a part of the embodiments of the present invention, and
It is not all of embodiment.Based on the embodiments of the present invention, ordinary people in the field is without making creative work
Every other embodiment obtained, all should belong to the range of protection of the invention.
In the following description, numerous specific details are set forth in order to facilitate a full understanding of the present invention, but the present invention can be with
Implemented using other than the one described here other way, those skilled in the art can be without prejudice to intension of the present invention
In the case of do similar popularization, therefore the present invention is not limited by the specific embodiments disclosed below.
Secondly, " one embodiment " or " embodiment " referred to herein, which refers to, may be included at least one realization side of the invention
A particular feature, structure, or characteristic in formula." in one embodiment " that different places occur in the present specification not refers both to
The same embodiment, nor the individual or selective embodiment mutually exclusive with other embodiments.
Embodiment 1
Scalp care compositions composition proportion 1 of the present invention:
Above-mentioned scalp care compositions the preparation method is as follows:
(1) water phase oil is mutually weighed respectively and is better than in corresponding beaker heating water bath to 80 DEG C;
(2) the oil phase is added to the aqueous phase homogenizer homogeneous, speed 3000r/s homogenizing time 3 minutes, obtain primary emulsion;
(3) plant extracts and Pidolidone is added when being cooled to 50 DEG C;
(4) primary emulsion for obtaining homogeneous high pressure homogenizer homogeneous, using gradient homogeneous method, gradient homogeneous is successively
Are as follows: 40MPa homogeneous 5 times;60Mpa homogeneous 5 times;80Mpa homogeneous 5 times, form nanoemulsions;
(5) by the lotion of preparation through aseptic subpackaged into spray bottle, it is spraying that nanoemulsions are made.
It is measured through epidermis dehydration value (TEWL):
The scalp care nanoemulsions spray composite for selecting embodiment 1, is sprayed on after having cleaned scalp and hair daily
Scalp is massaged into absorption, and a selected build skin measures 3 times every time, takes its average value;Measure first day use preceding 0h, 1h, 3h and
The skin of 5h, continuous use 28 days after 0h, 1h, 3h and 5h through epidermis dehydration value.Figure it is seen that the skin screen of scalp
Barrier has obtained good reparation, and transepidermal water loss value reduces and moisture of skin is lost reduction at any time.
Embodiment 2
Scalp care compositions composition proportion 2 of the present invention:
Embodiment 3
Scalp care compositions composition proportion 3 of the present invention:
Embodiment 4 (comparative example 1)
On the basis of other components and experiment condition same as Example 1, macromolecule moisturizer is not used.
The test of moisture content of skin and transepidermal water loss value:
Using German Corneometer CK-MPA moisture of skin tester, moisture content survey is carried out to subject's scalp
Fixed, the scalp of selected position measures 3 times, takes its average value;By measuring before use, using rear 1h, after rear 3h and use
The variation of the moisture content of skin numerical value of 5h is as shown in Figure 1 to assess the moisture-keeping efficacy of formula.It can be seen that the water content of embodiment 1
Higher and water tariff collection is more more longlasting than comparative example 1, while the moisture content of embodiment 1 and water tariff collection are better than embodiment 2
With embodiment 3, this is because water phase selected by embodiment 1, oil are mutually and vegetable active extract components and its specific proportion
Synergistic function.
Embodiment 5 (comparative example 2)
On the basis of other components and experiment condition same as Example 1, plant extracts is not added.
The microorganism detection of nanoemulsions spray composite obtained:
Test method: using sterile saline dilute sample, using the total plate count in colony counting method measurement sample.With
Sterilized straw draws the diluted inspection liquid 2mL of 1:10, is injected separately into two sterilizing plates, every ware lmL.Separately lmL is taken to be injected into
(suction pipe is not made to contact liquid level) in 9mL sterile saline test tube to mix well, 1:100 inspection liquid is made.A branched pipette is replaced, is inhaled
2mL is taken to be injected separately into two sterilizing plates, every ware lmL.It will melt and be cooled to 45~50 DEG C of lecithin Tween-80 battalion
Feeding agar medium is poured into the above-mentioned plate equipped with detection liquid, and every ware about 15mL rotates plate immediately, makes sample and culture
Base is sufficiently mixed uniformly, after agar solidification, is overturn plate, is set and cultivate 48 ± 2h in 36 scholar, 1 DEG C of incubator.Separately one is taken to be not added
About 15mL lecithin Tween-80 agar medium is added in the sterilizing sky plate of sample, after agar solidification, overturns plate, sets 36
48 ± 2h is cultivated in ± 1 DEG C of incubator, as blank control.
Test period: it 10 weeks, surveys weekly primary.
The nanoemulsions chosen in above-described embodiment 1~3 first place each sample one month at room temperature, observe each receive
Whether the performance of rice milk liquid system changes.Each sample is put into 37 DEG C of biochemical cultivation cases again, it is therefore an objective to provide for microorganism
Suitable growing environment, to shorten experimental period.Its microorganism detection the results are shown in Table 1.
The experiment of table 1 measures total plate count in Examples 1 to 3 and comparative example 2
Although can be seen that the nanoemulsions that the present invention is prepared from the data of table 1 does not add preservative, still
With good anti-microbial property.
Embodiment 6 (comparative example 3)
On the basis of other components and experiment condition same as Example 1, it is made into the ordinary emulsion of non-nano.
Embodiment 1 is compared with 3 stability of comparative example
Detect example:
The spraying partial size test of nanoemulsions
Using the partial size of Zetasizer Nano S90 molecule/granularity and zeta potentiometric analyzer measurement nanoemulsions.It is flat
Equal partial size 150nm.As shown in Figure 4.
The ordinary emulsion of the nanoemulsions of the embodiment 1 prepared and comparative example 3 is both placed at 45 DEG C and -15 DEG C,
It is for 24 hours alternately once a cycle, totally 7 periods, observation emulsion intercalation method change.Experimental result is shown in Table 2.
2 Examples 1 to 3 of table is compared with 3 stability of comparative example
Period | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example 3 |
0 | - | - | - | - |
1 | - | - | - | - |
2 | - | - | - | - |
3 | - | - | - | - |
4 | - | - | - | - |
5 | - | - | - | + |
6 | - | - | - | + |
7 | - | - | - | + |
"-" indicates that lotion does not change."+" indicates creaming of emulsion
By table 2 it is visible if being made into ordinary emulsion 45 DEG C to -15 DEG C circulation five times i.e. be layered, illustrate non-nano
Ordinary emulsion stability is bad.
Embodiment 7 (comparative example 4)
On the basis of other components and experiment condition same as Example 1, it is made into common bottled non-sprayable emulsion.
The person that has dandruff of itching dry to 30 typical scalps carries out continuing tracking and testing, and experimental result is shown in Fig. 3.From result as it can be seen that
Select no matter antipruritic, repairing effect, moist, abdomen sense and anti-dandruff effect, the film comfort level with when preparation method of embodiment 1 all
It is significantly better than other proportions.
Embodiment 8
The influence that different vegetable active extracts grow Bacteria suppression
The preparation of bacterium solution: by staphylococcus aureus, saccharomyces albicans, Escherichia coli, pseudomonas aeruginosa it is general
Logical agar plate 18h culture matches every milliliter of turbidity bacterium containing about 900,000,000 bacteriums with sterile saline respectively using turbidimetry
Liquid.
Agar diffusion method: bacterium solution is picked with aseptic cotton carrier and makees uniformly intensively to cross on plain agar plate, 5mm is beaten in aperture
A kind of extracting solution liquid is filled it up in the punching of hole device, every hole, and 37 DEG C of incubator effects for 24 hours, measure antibacterial circle diameter size with ruler, with for 24 hours
Completely not long bacterium records every kind of extracting solution to the antibacterial circle diameter of every kind of bacterium as measurement standard respectively.With antibacterial circle diameter
The above are effective by 10mm.Experimental result is shown in Table 3.
The influence that the different vegetable active extracts of table 3 grow Bacteria suppression
"-" indicates no bacterial growth, and "+" indicates bacterial growth
Three kinds of plant activity extracts can play collaboration bacteriostasis seen from table 3.
It should be noted that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although referring to preferable
Embodiment describes the invention in detail, those skilled in the art should understand that, it can be to technology of the invention
Scheme is modified or replaced equivalently, and without departing from the spirit and scope of the technical solution of the present invention, should all be covered in this hair
In bright scope of the claims.
Claims (2)
1. a kind of scalp care compositions, it is characterised in that: the scalp care compositions, component are divided by percentage to the quality
Not are as follows:
EDTA-2Na content is 0.05%, and hexylene glycol content is 2%, glycerol content 4%, and hyaluronic acid sodium content is
0.05%, tremella polysaccharides content is 0.05%, and panthenol content is 0.5%, serine content 0.2%, and arginine content is
0.1%, beet alkali content 1%, erythrose alcohol content is 1%, and white pond flower seed oil content is 4%, and content of phytosterol is
1%, seed of Flos Camelliae Japonicae oil content is 2%, and ceramide content 1%, isohexadecane content is 2%, and hydrolecithin content is
1%, jojoba oil content is 2%, and Eucalyptus globulus Labill leaf extractive content is 4%, and Cacumen Platycladi extract content is 5%, and frutus cnidii extracts
Object content is 5%, and oat extract content is 4%, and peony root extractive content is 2%, and radix scutellariae content is 4%, rosemary leave
Extractive content is 0.2%, and Pidolidone is water for adjusting pH value, remainder;
The scalp care compositions are nanoemulsions spray composite.
2. the method for preparing scalp care compositions described in claim 1, it is characterised in that: including,
Heating: the water phase of the composition and oil phase component are heated respectively;
Homogeneous: it is primary emulsion that water phase homogenizer homogeneous, which is added, in the oil phase component;
It is cooling: plant extracts will to be added after primary emulsion cooling;
It prepares nanoemulsions: nanometer will be made using gradient homogeneous method through overcooled primary emulsion high pressure homogenizer homogeneous
Lotion;
Preparation is spraying: the nanoemulsions being dispensed into spray bottle, it is spraying that nanoemulsions are made;
The heating, temperature are 80 DEG C;
The homogeneous, speed 3000r/s, time 3min;Plant extracts is added when being cooled to 50 DEG C in the cooling;Institute
Gradient homogeneous is stated, successively are as follows: 40MPa homogeneous 5 times;60Mpa homogeneous 5 times;80Mpa homogeneous 5 times.
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CN109646372A (en) * | 2019-01-14 | 2019-04-19 | 澳宝化妆品(惠州)有限公司 | One kind scalp care compositions of leaf extract containing aloe barbadensis Miller and preparation method thereof |
CN110279624A (en) * | 2019-07-09 | 2019-09-27 | 广州澳希亚实业有限公司 | A kind of scalp care compositions and its application in treatment |
CN110974771A (en) * | 2019-12-27 | 2020-04-10 | 广州蜜妆生物科技有限公司 | Scalp care composition and application thereof |
CN111166682A (en) * | 2020-01-17 | 2020-05-19 | 广州娇兰佳人化妆品连锁有限公司 | Micro-emulsified skin care emulsion and preparation method thereof |
CN111228183A (en) * | 2020-03-24 | 2020-06-05 | 广州睿新生物科技有限公司 | Composition for conditioning skin and preparation method thereof |
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CN105662918A (en) * | 2016-01-15 | 2016-06-15 | 天津天狮生物发展有限公司 | Essence for care of scalp and hair root as well as preparation method thereof |
CN106420550A (en) * | 2016-08-29 | 2017-02-22 | 澳宝化妆品(惠州)有限公司 | Prunus-amygdalus-dulcis-fruit hair caring composition |
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