CN108785242B - Cosmetic composition and preparation method thereof - Google Patents
Cosmetic composition and preparation method thereof Download PDFInfo
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- CN108785242B CN108785242B CN201810842139.9A CN201810842139A CN108785242B CN 108785242 B CN108785242 B CN 108785242B CN 201810842139 A CN201810842139 A CN 201810842139A CN 108785242 B CN108785242 B CN 108785242B
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- 239000000203 mixture Substances 0.000 title claims abstract description 98
- 239000002537 cosmetic Substances 0.000 title claims abstract description 83
- 238000002360 preparation method Methods 0.000 title claims abstract description 34
- 239000000284 extract Substances 0.000 claims abstract description 137
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 102
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims abstract description 72
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 69
- 230000001815 facial effect Effects 0.000 claims abstract description 67
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 57
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 57
- 241000195493 Cryptophyta Species 0.000 claims abstract description 56
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims abstract description 35
- 229960000458 allantoin Drugs 0.000 claims abstract description 35
- 241001478240 Coccus Species 0.000 claims abstract description 34
- 241000220259 Raphanus Species 0.000 claims abstract description 34
- 235000006140 Raphanus sativus var sativus Nutrition 0.000 claims abstract description 34
- 239000000706 filtrate Substances 0.000 claims abstract description 33
- 241001071795 Gentiana Species 0.000 claims abstract description 30
- 241000235342 Saccharomycetes Species 0.000 claims abstract description 30
- 230000009089 cytolysis Effects 0.000 claims abstract description 30
- 241000628997 Flos Species 0.000 claims abstract description 22
- YPFDHNVEDLHUCE-UHFFFAOYSA-N propane-1,3-diol Chemical compound OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 claims abstract description 21
- 229960003237 betaine Drugs 0.000 claims abstract description 19
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 238000000034 method Methods 0.000 claims description 32
- 244000047670 Viola x wittrockiana Species 0.000 claims description 30
- 235000004031 Viola x wittrockiana Nutrition 0.000 claims description 30
- 230000007062 hydrolysis Effects 0.000 claims description 29
- 238000006460 hydrolysis reaction Methods 0.000 claims description 29
- DTTVNCZEOYSFFF-UHFFFAOYSA-N ethoxyurea Chemical compound CCONC(N)=O DTTVNCZEOYSFFF-UHFFFAOYSA-N 0.000 claims description 20
- 238000001816 cooling Methods 0.000 claims description 19
- 239000000835 fiber Substances 0.000 claims description 11
- 150000003384 small molecules Chemical class 0.000 claims description 9
- 241000894006 Bacteria Species 0.000 claims description 8
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 8
- 239000012528 membrane Substances 0.000 claims description 8
- 229910052708 sodium Inorganic materials 0.000 claims description 8
- 239000011734 sodium Substances 0.000 claims description 8
- 238000012545 processing Methods 0.000 claims description 7
- 239000002253 acid Substances 0.000 claims description 6
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 4
- 239000011259 mixed solution Substances 0.000 claims description 4
- 239000004202 carbamide Substances 0.000 claims description 3
- DIBAKBGYJUCGDL-UHFFFAOYSA-N 2,6-diamino-n-[1-[(2-amino-2-oxoethyl)amino]-3-(1h-imidazol-5-yl)-1-oxopropan-2-yl]hexanamide Chemical compound NCCCCC(N)C(=O)NC(C(=O)NCC(N)=O)CC1=CN=CN1 DIBAKBGYJUCGDL-UHFFFAOYSA-N 0.000 claims description 2
- 241000196324 Embryophyta Species 0.000 claims description 2
- 108010026970 bursopoietin Proteins 0.000 claims description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
- 239000000779 smoke Substances 0.000 claims description 2
- 210000002700 urine Anatomy 0.000 claims description 2
- 244000178870 Lavandula angustifolia Species 0.000 claims 2
- 235000010663 Lavandula angustifolia Nutrition 0.000 claims 2
- 239000001102 lavandula vera Substances 0.000 claims 2
- 235000018219 lavender Nutrition 0.000 claims 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
- 229920002674 hyaluronan Polymers 0.000 claims 1
- 229960003160 hyaluronic acid Drugs 0.000 claims 1
- 239000000126 substance Substances 0.000 abstract description 19
- 239000003755 preservative agent Substances 0.000 abstract description 14
- 230000002335 preservative effect Effects 0.000 abstract description 13
- 230000037307 sensitive skin Effects 0.000 abstract description 13
- 206010020751 Hypersensitivity Diseases 0.000 abstract description 7
- 208000026935 allergic disease Diseases 0.000 abstract description 7
- 230000007815 allergy Effects 0.000 abstract description 7
- 230000000052 comparative effect Effects 0.000 description 23
- 230000000694 effects Effects 0.000 description 15
- 238000012360 testing method Methods 0.000 description 14
- 238000003756 stirring Methods 0.000 description 13
- 239000000463 material Substances 0.000 description 12
- 239000006185 dispersion Substances 0.000 description 10
- 239000007788 liquid Substances 0.000 description 8
- NIPNSKYNPDTRPC-UHFFFAOYSA-N N-[2-oxo-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 NIPNSKYNPDTRPC-UHFFFAOYSA-N 0.000 description 6
- 206010040880 Skin irritation Diseases 0.000 description 6
- 230000000845 anti-microbial effect Effects 0.000 description 6
- 238000001514 detection method Methods 0.000 description 6
- 238000011156 evaluation Methods 0.000 description 6
- 239000004615 ingredient Substances 0.000 description 6
- 238000004321 preservation Methods 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 239000002994 raw material Substances 0.000 description 6
- 230000036556 skin irritation Effects 0.000 description 6
- 231100000475 skin irritation Toxicity 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 210000004379 membrane Anatomy 0.000 description 5
- 230000001953 sensory effect Effects 0.000 description 5
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 description 4
- -1 4-HBA methyl esters Chemical class 0.000 description 4
- 239000003513 alkali Substances 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 238000005260 corrosion Methods 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 230000007794 irritation Effects 0.000 description 4
- 238000005259 measurement Methods 0.000 description 4
- 235000016068 Berberis vulgaris Nutrition 0.000 description 3
- 241000335053 Beta vulgaris Species 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 229920000433 Lyocell Polymers 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 230000007797 corrosion Effects 0.000 description 3
- 230000000670 limiting effect Effects 0.000 description 3
- 239000004745 nonwoven fabric Substances 0.000 description 3
- 238000009738 saturating Methods 0.000 description 3
- 241000283977 Oryctolagus Species 0.000 description 2
- 210000002469 basement membrane Anatomy 0.000 description 2
- 235000013877 carbamide Nutrition 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000007705 chemical test Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 description 2
- 230000008595 infiltration Effects 0.000 description 2
- 238000001764 infiltration Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 230000003020 moisturizing effect Effects 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 208000035824 paresthesia Diseases 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 239000011265 semifinished product Substances 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 description 1
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N 4-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 241000228245 Aspergillus niger Species 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- QOSMNYMQXIVWKY-UHFFFAOYSA-N Propyl levulinate Chemical compound CCCOC(=O)CCC(C)=O QOSMNYMQXIVWKY-UHFFFAOYSA-N 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000003260 anti-sepsis Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 239000006059 cover glass Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 229960005323 phenoxyethanol Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 229940112950 sage extract Drugs 0.000 description 1
- 235000020752 sage extract Nutrition 0.000 description 1
- 239000013535 sea water Substances 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 210000000697 sensory organ Anatomy 0.000 description 1
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- 238000003860 storage Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9717—Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
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- A—HUMAN NECESSITIES
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to cosmetic compositions.The cosmetic composition includes: water, allantoin, 1,3- propylene glycol, macromolecular Sodium Hyaluronate, purple ball algae extract, glycine betaine, algae extract, saccharomycete lysis object extract, gentian root extract, lavandulae flos water and bright string coccus/radish root tunning filtrate.The facial mask stability of cosmetic composition preparation is good, while not needing additionally to add chemical preservative, and the quality of facial mask is made to be guaranteed from source, mildly non-stimulated to skin, greatly reduces the probability of allergy, and pregnant woman or sensitive skin can be used for a long time.
Description
Technical field
The present invention relates to cosmetic field, in particular it relates to cosmetic composition and preparation method thereof, more specifically
Ground, the present invention relates to cosmetic composition, the preparation method of cosmetic composition, the preparation methods of facial mask and facial mask.
Background technique
It is to make up makeup removing and the still insufficient cleaning that washes one's face that it is also most important purpose that facial mask is most basic, basic herein
The upper other essential ingredients of cooperation realize other maintenance functions, such as replenishing water and preserving moisture, whitening and anti-aging, Sage Extract etc..
Summary of the invention
The application is to be made based on inventor to the discovery of following facts and problem and understanding:
Contain certain moisture and nutritional ingredient in facial mask, yeast and mold is easy in a humid environment grows, is numerous
It grows.Therefore, in presently commercially available facial mask, reach corrosion-resistant effect mostly to add chemical preservative, preservative is many kinds of, frequency
The higher kind of rate is 4-HBA methyl esters, Phenoxyethanol, methylisothiazolinone and 4-HBA propyl ester etc.,
These chemical preservatives have certain irritation to skin, and skin excessively continually contacts that can lead to allergy anti-with preservative
It answers.In addition, the material of presently commercially available mounted facial mask is usually silk, tencel, non-woven fabrics or pure cotton fiber, however, this kind of material
Mounted facial mask to sensitive skin crowd especially pregnant women have certain irritation, the sensitive skin crowd especially pregnancy period
Women is easy to appear allergic phenomena using the mounted facial mask of this kind of material and addition chemical preservative.
Discovery based on the above issues, inventor have researched and developed a kind of new makeup by countless experimental explorings
Product composition, the cosmetics of cosmetic composition preparation, such as facial mask, stability is good, while not needing additionally to add chemical anti-
Rotten agent makes the quality of facial mask be guaranteed from source, mildly non-stimulated to skin, greatly reduces the probability of allergy, pregnant woman
Or sensitive skin can be used for a long time；In addition, inventor replaces silk, tencel, non-woven fabrics or pure cotton fiber using biological fiber,
Making the facial mask of preparation has the dermatoid function of class, and docile water holding capacity is excellent, and good biocompatibility is nonirritant.
For this purpose, the invention proposes a kind of cosmetic compositions in the first aspect of the present invention.Implementation according to the present invention
Example, the cosmetic composition include: water, allantoin, 1,3-PD, macromolecular Sodium Hyaluronate, purple ball algae extract, sweet tea
Dish alkali, algae extract, saccharomycete lysis object extract, gentian root extract, lavandulae flos water and bright string coccus/radish root
Tunning filtrate.In the presence of other ingredients in the 1,3-PD and formula are common, cosmetic composition preparation
Facial mask stability it is preferable, there is good cold resistance and heat resistance, while mild, comfortable, water profit, smooth, with skin
Compactness is preferable；State clearly string coccus/radish root tunning filtrate and formula in other ingredients it is common in the presence of, describedization
The facial mask of cosmetic compositions preparation can play good antisepsis, and then without additional addition chemical preservative.According to this
The cosmetics of the cosmetic composition preparation of inventive embodiments, such as facial mask, stability is good, while not needing additionally to add chemical anti-
Rotten agent makes the quality of facial mask be guaranteed from source, mildly non-stimulated to skin, greatly reduces the probability of allergy, pregnant woman
Or sensitive skin can be used for a long time.
According to an embodiment of the invention, above-mentioned cosmetic composition can also further comprise following additional technical feature at least
One of:
According to an embodiment of the invention, the cosmetic composition further comprises micromolecule hyaluronic acid sodium, ethoxy
At least one of urea and hydrolysis heartsease extract.Inventors have found that micromolecule hyaluronic acid sodium is less than 10K, transdermal can inhale
It receives, deep layer nurses skin, has the multiple activities such as moisturizing, reparation, anti-oxidant；Ethoxy urea is capable of providing fabulous moisturizing effect
Fruit increases the elasticity of skin, improves the skin sense of formula；Hydrolysis heartsease extract can go deep into cell, strengthen Water Transportation, allow
Skin moisture maintains dynamic equilibrium.In turn, the cosmetics of cosmetic composition preparation according to an embodiment of the present invention, such as facial mask,
Performance of keeping humidity is more excellent.
According to an embodiment of the invention, the parts by weight of the water are 60-90, the parts by weight of the allantoin are 0.01-1,
The parts by weight of the 1,3-PD are 2-8, and the parts by weight of the macromolecular Sodium Hyaluronate are 0.01-1, and the small molecule is saturating
The parts by weight of bright matter acid sodium are 0-1, and the parts by weight of the purple ball algae extract are 0.01-2, and the parts by weight of the ethoxy urea are
0-1, the parts by weight of the hydrolysis heartsease extract are 0-1, and the parts by weight of the glycine betaine are 0.1-5, the algae extract
Parts by weight be 0.1-4, the parts by weight of the saccharomycete lysis object extract are 0.01-1, the weight of the gentian root extract
Amount part is 0.01-1, and the parts by weight of the lavandulae flos water are 0.5-3, and states string coccus/radish root tunning filter clearly
The parts by weight of liquid are 1-4.Inventors have found that in the cosmetic composition parts by weight of each component in the range when, preparation
The stability of facial mask, anti-corrosive properties and more excellent with the stickiness of skin.
According to an embodiment of the invention, the parts by weight of the water are 68.56-89.8, the parts by weight of the allantoin are
The parts by weight of 0.01-0.5, the 1,3-PD are 2.35-7.65, and the parts by weight of the macromolecular Sodium Hyaluronate are
0.01-0.80, the parts by weight of the micromolecule hyaluronic acid sodium are 0-0.5, and the parts by weight of the purple ball algae extract are 0.05-
1.36, the parts by weight of the ethoxy urea are 0-0.83, and the parts by weight of the hydrolysis heartsease extract are 0.3-0.72, described
The parts by weight of glycine betaine are 0.5-4.2, and the parts by weight of the algae extract are 0.5-3.3, the saccharomycete lysis object extract
Parts by weight be 0.01-0.80, the parts by weight of the gentian root extract are 0.03-0.76, the weight of the lavandulae flos water
Amount part is 0.8-2.5, and stating string coccus/radish root tunning filtrate parts by weight clearly is 1.5-3.Inventors have found that
In the cosmetic composition parts by weight of each component in the range when, the stability of the facial mask of preparation, anti-corrosive properties and with
The stickiness of skin advanced optimizes.
According to an embodiment of the invention, the parts by weight of the water are 75-88, such as 78,80,85；The weight of the allantoin
Part is 0.01-0.1, such as 0.02,0.06,0.08；The parts by weight of the 1,3-PD be 2.35-6.8, such as 2.5,3.0,3.5,
4.0,4.5,5.0,5.5,6.0,6.5；The parts by weight of the macromolecular Sodium Hyaluronate be 0.1-0.8, such as 0.2,0.3,0.4,
0.5,0.6,0.7；The parts by weight of the micromolecule hyaluronic acid sodium be 0-0.1, such as 0.01,0.02,0.03,0.05,0.07,
0.09；The parts by weight of the purple ball algae extract are 0.05-1.36, such as 0.1,0.3,0.5,0.7,0.8,0.9,1.0,1.2；Institute
The parts by weight for stating ethoxy urea are 0-0.83, such as 0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8；The hydrolysis heartsease mentions
The parts by weight for taking object are 0.3-0.68, such as 0.4,0.5,0.6；The parts by weight of the glycine betaine be 0.5-4.2, such as 1.0,1.5,
2.0,2.5,3.0,3.5,4.0；The parts by weight of the algae extract are 0.5-3.3, such as 1.0,1.5,2.0,2.5,3.0；It is described
The parts by weight of saccharomycete lysis object extract be 0.05-0.80,0.10,0.15,0.20,0.25,0.30,0.40,0.50,
0.60,0.70；The parts by weight of the gentian root extract be 0.03-0.76, such as 0.10,0.15,0.20,0.25,0.30,
0.35,0.40,0.50,0.60,0.70；The parts by weight of the lavandulae flos water be 0.85-2.12, such as 0.9,1.0,1.2,1.5,
2.0；And stating string coccus/radish root tunning filtrate parts by weight clearly is 1.5-3, such as 2.0,2.5.
It will be appreciated by persons skilled in the art that each component in present invention cosmetic composition claimed can
To provide in many ways, for example, can be provided in the form of graininess, powdered, gel, dispersion liquid or solution etc..Change sentence
It talks about, it, can be with the shape of powder such as the component macromolecular Sodium Hyaluronate in the application cosmetic composition claimed
Formula provides, and can also provide in the form of granules, or provides in the form of dispersion liquid (being scattered in 1,3-PD).
But no matter each component provides in which way, it should all finally meet present invention cosmetics claimed
The ingredient or content requirement of composition totality.In other words, such as the component in the application cosmetic composition claimed
When macromolecular Sodium Hyaluronate and micromolecule hyaluronic acid sodium are provided in the form of being scattered in 1,3-PD, macromolecular hyalomitome
Sour sodium, micromolecule hyaluronic acid sodium and 1,3- propylene glycol all will be as in present invention cosmetic compositions claimed
Effective component, the content of macromolecular Sodium Hyaluronate, micromolecule hyaluronic acid sodium and 1,3-PD should all also meet this hair
The content requirement of bright cosmetic composition claimed.
According to an embodiment of the invention, the allantoin is provided in the form of being dissolved in water.Inventors have found that the urine
When Bursin is provided in the form of being dissolved in water, the dispersion of allantoin is more uniform, more excellent with the fiting effect of other components, in turn,
The stability of the facial mask of preparation and more excellent with the stickiness of skin.
According to an embodiment of the invention, the weight ratio of the allantoin and water is (0.01-1): (60-90).Invention human hair
Existing, the allantoin is provided in the form of being dissolved in water, while weight ratio, in the range, the dispersion of allantoin is more uniform, with
The fiting effect of other components is more excellent, in turn, the stability of the facial mask of preparation and advanced optimizes with the stickiness of skin.
According to an embodiment of the invention, the weight ratio of the allantoin and water is (0.01-0.5): (68.56-89.8).Hair
Bright people's discovery, the allantoin is provided in the form of being dissolved in water, while weight ratio, in the range, the dispersion of allantoin is more equal
It is even, it is more excellent with the fiting effect of other components, in turn, the stability of the facial mask of preparation and further excellent with the stickiness of skin
Change.
According to an embodiment of the invention, the weight ratio of the allantoin and water is (0.01-0.1): (75-88).
According to an embodiment of the invention, the macromolecular Sodium Hyaluronate and optional micromolecule hyaluronic acid sodium are to divide
Dissipate in 1,3- propylene glycol form offer.Inventors have found that the macromolecular Sodium Hyaluronate and optional small molecule are transparent
When matter acid sodium is provided in the form of being scattered in 1,3-PD, macromolecular Sodium Hyaluronate and optional micromolecule hyaluronic acid sodium
Dispersion it is more uniform, it is more excellent with the fiting effect of other components, in turn, the stability of the facial mask of preparation and the patch with skin
Conjunction property is more excellent.
According to an embodiment of the invention, the macromolecular Sodium Hyaluronate, micromolecule hyaluronic acid sodium and 1,3-PD
Weight ratio be (0.01-1): (0-1): (2-8).Inventors have found that the macromolecular Sodium Hyaluronate and optional small molecule
Sodium Hyaluronate is provided in the form of being scattered in 1,3-PD, while weight ratio is in the range, macromolecular Sodium Hyaluronate
It is more uniform with the dispersion of optional micromolecule hyaluronic acid sodium, it is more excellent with the fiting effect of other components, in turn, the face of preparation
It the stability of film and is advanced optimized with the stickiness of skin.
According to an embodiment of the invention, the macromolecular Sodium Hyaluronate, micromolecule hyaluronic acid sodium and 1,3-PD
Weight ratio be (0.01-0.80): (0-0.5): (2.35-7.65).Inventors have found that the macromolecular Sodium Hyaluronate and appoint
The micromolecule hyaluronic acid sodium of choosing is provided in the form of being scattered in 1,3-PD, while weight ratio is in the range, macromolecular
The dispersion of Sodium Hyaluronate and optional micromolecule hyaluronic acid sodium is more uniform, more excellent with the fiting effect of other components, into
And it the stability of the facial mask of preparation and is advanced optimized with the stickiness of skin.
According to an embodiment of the invention, the macromolecular Sodium Hyaluronate, micromolecule hyaluronic acid sodium and 1,3-PD
Weight ratio be (0.1-0.8): (0-0.1): (2.35-6.8).
In the second aspect of the present invention, the invention proposes a kind of cosmetic compositions.According to an embodiment of the invention, institute
State the water that cosmetic composition includes: 87.303 weight %, the allantoin of 0.032 weight %, 1, the 3- of 4.5 weight % the third two
Alcohol, the macromolecular Sodium Hyaluronate of 0.32 weight %, the micromolecule hyaluronic acid sodium of 0.012 weight %, the purple of 0.85 weight %
Ball algae extract, the ethoxy urea of 0.43 weight %, the hydrolysis heartsease extract of 0.46 weight %, the beet of 1.6 weight %
Alkali, the algae extract of 1.8 weight %, the saccharomycete lysis object extract of 0.113 weight %, the gentian root of 0.12 weight % mention
Take object, bright string coccus/radish root tunning filtrate of the lavandulae flos water of 0.93 weight % and 1.53 weight %.
In the third aspect of the present invention, the invention proposes a kind of cosmetic compositions.According to an embodiment of the invention, institute
State the water that cosmetic composition includes: 84.509 weight %, the allantoin of 0.056 weight %, 1, the 3- of 5.19 weight % the third two
Alcohol, the macromolecular Sodium Hyaluronate of 0.443 weight %, the micromolecule hyaluronic acid sodium of 0.024 weight %, the purple of 0.99 weight %
Ball algae extract, the ethoxy urea of 0.49 weight %, the hydrolysis heartsease extract of 0.51 weight %, the beet of 1.95 weight %
Alkali, the algae extract of 2.1 weight %, the saccharomycete lysis object extract of 0.235 weight %, the gentian root of 0.391 weight %
The bright string coccus of extract, the lavandulae flos water of 1.26 weight % and 1.852 weight %/radish root tunning filtrate.
In the fourth aspect of the present invention, the invention proposes a kind of cosmetic compositions.According to an embodiment of the invention, institute
State the water that cosmetic composition includes: 78.43 weight %, the allantoin of 0.021 weight %, 1, the 3- of 6.25 weight % the third two
Alcohol, the macromolecular Sodium Hyaluronate of 0.465 weight %, the micromolecule hyaluronic acid sodium of 0.048 weight %, the purple of 1.05 weight %
Ball algae extract, the ethoxy urea of 0.75 weight %, the hydrolysis heartsease extract of 0.62 weight %, the beet of 3.3 weight %
Alkali, the algae extract of 2.6 weight %, the saccharomycete lysis object extract of 0.726 weight %, the gentian root of 0.73 weight % mention
Take object, bright string coccus/radish root tunning filtrate of the lavandulae flos water of 2.05 weight % and 2.96 weight %.
In the fifth aspect of the invention, the invention proposes a kind of methods for preparing cosmetic composition.According to the present invention
Embodiment, which comprises
Allantoin and water are subjected to the first mixed processing, to obtain the first mixture；
First mixture is heated, it is described heat treatment be 80.5-84.5 DEG C at a temperature of carry out
3-7min；
First mixture after heat treatment is subjected to the first cooling treatment, the temperature after first cooling treatment
It is 50.5-54.5 DEG C；
By after the first cooling treatment first mixture and macromolecular Sodium Hyaluronate and optional small molecule it is transparent
The mixed solution of matter acid sodium carries out the second mixed processing, to obtain the second mixture；
Second mixture is subjected to the second cooling treatment, the temperature after second cooling treatment is 40.5-44.5
℃；
By second mixture and purple ball algae extract, glycine betaine, algae extract, saccharomycete after the second cooling treatment
Lysis object extract, gentian root extract, lavandulae flos water, bright string coccus/radish root tunning filtrate and optional
Ethoxy urea and/or hydrolysis heartsease extract carry out third mixed processing, to obtain the cosmetic composition；
Wherein, the mixed solution of the macromolecular Sodium Hyaluronate and optional micromolecule hyaluronic acid sodium includes macromolecular
Sodium Hyaluronate, 1,3- propylene glycol and optional micromolecule hyaluronic acid sodium.
Inventors have found that under the second cooling temperature carry out third mixed processing, obtained cosmetic composition it is steady
Qualitative good, moistening effect is more preferably.The facial mask that the cosmetic composition prepared according to the method for the embodiment of the present invention prepares, surely
It is qualitative good, while not needing additionally to add chemical preservative, so that the quality of facial mask is guaranteed from source, to the mild nothing of skin
Stimulation, greatly reduces the probability of allergy, and pregnant woman or sensitive skin can be used for a long time.
According to an embodiment of the invention, the above method can also further comprise at least one following additional technical feature:
According to an embodiment of the invention, the parts by weight of the water are 60-90, the parts by weight of the allantoin are 0.01-1,
The parts by weight of the 1,3-PD are 2-8, and the parts by weight of the macromolecular Sodium Hyaluronate are 0.01-1, and the small molecule is saturating
The parts by weight of bright matter acid sodium are 0-1, and the parts by weight of the purple ball algae extract are 0.01-2, and the parts by weight of the ethoxy urea are
0-1, the parts by weight of the hydrolysis heartsease extract are 0-1, and the parts by weight of the glycine betaine are 0.1-5, the algae extract
Parts by weight be 0.1-4, the parts by weight of the saccharomycete lysis object extract are 0.01-1, the weight of the gentian root extract
Amount part is 0.01-1, and the parts by weight of the lavandulae flos water are 0.5-3, states string coccus/radish root tunning filtrate clearly
Parts by weight are 1-4.
According to an embodiment of the invention, the parts by weight of the water are 68.56-89.8, the parts by weight of the allantoin are
The parts by weight of 0.01-0.5, the 1,3-PD are 2.35-7.65, and the parts by weight of the macromolecular Sodium Hyaluronate are
0.01-0.80, the parts by weight of the micromolecule hyaluronic acid sodium are 0-0.5, and the parts by weight of the purple ball algae extract are 0.05-
1.36, the parts by weight of the ethoxy urea are 0-0.83, and the parts by weight of the hydrolysis heartsease extract are 0.3-0.72, described
The parts by weight of glycine betaine are 0.5-4.2, and the parts by weight of the algae extract are 0.5-3.3, the saccharomycete lysis object extract
Parts by weight be 0.01-0.80, the parts by weight of the gentian root extract are 0.03-0.76, the weight of the lavandulae flos water
Amount part is 0.8-2.5, and stating string coccus/radish root tunning filtrate parts by weight clearly is 1.5-3.
According to an embodiment of the invention, the parts by weight of the water are 75-88, the parts by weight of the allantoin are 0.01-
0.1, the parts by weight of the 1,3-PD are 2.35-6.8, and the parts by weight of the macromolecular Sodium Hyaluronate are 0.1-0.8, institute
The parts by weight for stating micromolecule hyaluronic acid sodium are 0-0.1, and the parts by weight of the purple ball algae extract are 0.05-1.36, the hydroxyl
The parts by weight of ethyl carbamide are 0-0.83, and the parts by weight of the hydrolysis heartsease extract are 0.3-0.68, the weight of the glycine betaine
Amount part is 0.5-4.2, and the parts by weight of the algae extract are 0.5-3.3, and the parts by weight of the saccharomycete lysis object extract are
0.05-0.80, the parts by weight of the gentian root extract are 0.03-0.76, and the parts by weight of the lavandulae flos water are 0.85-
2.12, stating string coccus/radish root tunning filtrate parts by weight clearly is 1.5-3.
In the sixth aspect of the present invention, the invention proposes a kind of facial masks.According to an embodiment of the invention, the facial mask by
Cosmetic composition described in any of the above embodiments or the cosmetic composition preparation prepared according to method described in any of the above embodiments
It forms.The stability of facial mask according to an embodiment of the present invention is good, while not needing additionally to add chemical preservative, makes the matter of facial mask
Amount is guaranteed from source, mildly non-stimulated to skin, greatly reduces the probability of allergy, and pregnant woman or sensitive skin can be grown
Phase uses.
In the seventh aspect of the present invention, the invention proposes a kind of facial masks.According to an embodiment of the invention, the facial mask packet
It includes: cosmetic composition described in any of the above embodiments or the cosmetic composition according to method described in any of the above embodiments preparation.
The stability of facial mask according to an embodiment of the present invention is good, while not needing additionally to add chemical preservative, make the quality of facial mask from
It is guaranteed on source, it is mildly non-stimulated to skin, the probability of allergy is greatly reduced, pregnant woman or sensitive skin can make for a long time
With.
According to an embodiment of the invention, above-mentioned facial mask can also further comprise at least one following additional technical feature:
According to an embodiment of the invention, the facial mask further comprises: membrane of biological fibers；Wherein, the membrane of biological fibers
It is impregnated with cosmetic composition described in any of the above embodiments or the cosmetic combinations according to method described in any of the above embodiments preparation
Object.Inventors have found that replacing silk, tencel, non-woven fabrics or pure cotton fiber using biological fiber, the facial mask of preparation can be made to have
The dermatoid function of class, docile water holding capacity is excellent, and good biocompatibility is nonirritant.
In the eighth aspect of the present invention, the invention proposes a kind of methods for preparing facial mask.According to an embodiment of the invention,
The described method includes: by cosmetic composition described in any of the above embodiments or according to the change of method described in any of the above embodiments preparation
Cosmetic compositions carry out cooling treatment, to obtain the facial mask.The facial mask prepared according to the method for the embodiment of the present invention
Stability, anti-corrosive properties and excellent with the stickiness of skin.
According to an embodiment of the invention, the above method can also further comprise at least one following additional technical feature:
According to an embodiment of the invention, the temperature after the cooling treatment is not higher than 40 DEG C, storage temperature is at 25 DEG C of room temperature
Left and right is best.Inventors have found that in this temperature range, the anti-corrosive properties of facial mask are more excellent.
According to an embodiment of the invention, the method further includes: by membrane of biological fibers infiltration after cooling treatment
In cosmetic composition described in any of the above embodiments or the cosmetic composition prepared according to method described in any of the above embodiments.
Each raw material of cosmetic composition of the present invention is explained according to the usual understanding of those skilled in the art.For
The abundant each raw material for illustrating cosmetic composition of the present invention forms, now to purple ball algae extract, algae extract, saccharomycete
Lysis object extract, gentian root extract, lavandulae flos water, bright string coccus/radish root tunning filtrate, hydrolysis heartsease
Extract, macromolecular Sodium Hyaluronate and micromolecule hyaluronic acid sodium are specifically described, but should not be understood as to the present invention
Limitation.
Above-mentioned raw materials can be prepared voluntarily, can also directly buy acquisition in the market.Wherein, different manufacturers or not
Ingredient or content with the raw material of batch may slightly have difference, still, as long as can be realized the raw material in cosmetics group of the present invention
The function and effect in object are closed, within the scope of inventor is selectable.
Purple ball algae extract, algae extract in the present invention, gentian root extract, smoke saccharomycete lysis object extract
The meaning of clothing showy flowers of herbaceous plants water, bright string coccus/radish root tunning filtrate and hydrolysis heartsease extract is according to " international cosmetic is former
Material standard Chinese Names Catalogue " (version in 2015) understood.
Specifically, the principle active component of the purple ball algae extract in the present invention is the substance that purple ball algae is extracted, further
Ground, the purple ball algae extract in the present invention is by seawater (50-80 weight %), 1,3-PD (10-25 weight %) and purple ball
Substance (the 0.1-1 weight %) composition that algae is extracted.
The principle active component of saccharomycete lysis object extract in the present invention is the substance that saccharomycete lysis object extracts, into
One step, the substance that the saccharomycete lysis object extract in the present invention is extracted by water (73-74 weight %) and saccharomycete lysis object
(24-26 weight %) composition.
The principle active component of gentian root extract in the present invention is the substance that gentian root extracts, further,
Substance (the 1.0-70 weight that gentian root extract in the present invention is extracted by butanediol (0.5-30 weight %) and gentian root
Measure %) composition.
Bright string coccus/radish root tunning filtrate principle active component in the present invention is bright string coccus/radish root
The filtrate of tunning, further, bright string coccus/radish root tunning filtrate in the present invention is by water (48-52 weight
Measure %) and bright string coccus/radish root tunning filtrate (48-52 weight %) composition.
The principle active component of hydrolysis heartsease extract in the present invention is the substance for hydrolyzing heartsease and extracting, further
Ground, the present invention in hydrolysis heartsease extract by water (94-96 weight %), hydrolysis heartsease extract substance (2-4 weight
Measure %) and bright string coccus/radish root tunning filtrate (1-3 weight %) composition.Wherein, bright string coccus/radish root fermentation
The meaning of Product filtrate is same as above.
In addition, the molecular weight of the macromolecular Sodium Hyaluronate in the present invention is not less than 10kDa.
The molecular weight of micromolecule hyaluronic acid sodium in the present invention is less than 10kDa, further, the small molecule in the present invention
The molecular weight of Sodium Hyaluronate is in the range of 3k~10kDa.
Detailed description of the invention
Fig. 1 is sensitive skin subject's use feeling cylindricality schematic diagram according to an embodiment of the present invention.
Specific embodiment
The embodiment of the present invention is described below in detail, examples of the embodiments are shown in the accompanying drawings.Below with reference to
The embodiment of attached drawing description is exemplary, it is intended to is used to explain the present invention, and is not considered as limiting the invention.
Unless otherwise instructed, " infiltration " described herein refers to the whole uniformly leaching of the membrane of biological fibers for being used to prepare facial mask
Profit has the cosmetic composition of the application, and in other words, cosmetic composition is evenly distributed on membrane of biological fibers, biological fiber
The cosmetic composition liquid layer thickness of film surface is uniform.
In addition, " cosmetics " described herein can be interpreted broadly, both includes color make-up product, also includes skin care item,
Such as facial mask, mildy wash, bath oil.
Formula composition
The present invention provides a kind of preparation methods of no anti-corrosion biology facial mask, which is characterized in that entire formula adds with entire
Work technique does not add preservative, according to its formula composition of weight percent are as follows:
Production method
The production method of biological facial mask is to sequentially include the following steps: again after weighing above-mentioned raw material by weight ratio
1) purified water in A phase is added in beaker, then the allantoin in A phase is added in beaker, is stirred evenly,
It is heated to 80.5-84.5 DEG C, keeps the temperature 5min；
2) it then cools down while stirring, is down to 50.5-54.5 DEG C to temperature, scattered B phase in advance is added and is formulated, sufficiently
Stirring is to being completely dissolved；
3) it then cools down while stirring, is down to 40.5-44.5 DEG C to temperature, sequentially add C phase, the material in D phase, add
Continue to stir evenly after material；
4) 40 DEG C are down to hereinafter, stopping stirring to temperature, Physico-chemical tests are done in sampling, are discharged；
5) static, filling, semi-finished product of the present invention are suitble to fill the basement membrane that carrier is biomembrane.
Wherein, in step 2) B phase be formulated the preparation method comprises the following steps: by B phase macromolecular Sodium Hyaluronate, micromolecule hyaluronic acid
Sodium is added in the beaker containing B phase 1,3-PD, and stirring later to dispersion is in not conglomeration state.
In order to make the objectives, technical solutions, and advantages of the present invention clearer, below in conjunction with specific embodiment, to this
Invention is further elaborated.It should be understood that the specific embodiments described herein are merely illustrative of the present invention, not
For limiting the present invention.
Purple ball algae extract in embodiment is bought from Qi Huadun company (Givaudan)；Algae extract purchase is certainly
Sinerga S.P.；Saccharomycete lysis object extract, bright string coccus/radish root tunning filtrate and hydrolysis heartsease are extracted
Object is bought from Ken Tuo Industrial Technology Co., Ltd (Kento Industry CO., LTD)；The certainly special section of gentian root extract purchase
Nuo Bao Co., Ltd；Lavandulae flos water is bought from Nash Oils；Macromolecular Sodium Hyaluronate (trade name Sodium Hyaluronate) and
Micromolecule hyaluronic acid sodium (nano HA) is bought from Bloomage Freda Biopharm Co., Ltd..
Embodiment 1-3
The preparation of B phase materials: B phase macromolecular Sodium Hyaluronate, micromolecule hyaluronic acid sodium are added to containing B phase 1,3-
In the beaker of propylene glycol, stirring later to dispersion is in not conglomeration state.
1) purified water in A phase is added in beaker, then the allantoin in A phase is added in beaker, is stirred evenly,
It is heated to 80.5-84.5 DEG C, keeps the temperature 5min；
2) it then cools down while stirring, is down to 50.5-54.5 DEG C to solution temperature in 1), is added and shifts to an earlier date scattered B phase
Formula, is stirred well to and is completely dissolved；
3) it then cools down while stirring, is down to 40.5-44.5 DEG C to solution temperature in 2), sequentially add C phase, in D phase
Material continues to stir evenly after adding material；
4) 40 DEG C are down to hereinafter, stopping stirring to solution temperature in 3), Physico-chemical tests are done in sampling, are discharged；
5) static, filling, semi-finished product of the present invention are suitble to fill the basement membrane that carrier is biomembrane.
The specific data of formula composition weight ratio are as shown in table 1 below in embodiment 1-3.
Table 1: formula composition in embodiment 1-3
Comparative example 1-3
The specific data of formula composition weight ratio are as shown in table 2 below in comparative example 1-3.Table 2: formula group in comparative example 1-3
At
The preparation process of comparative example 1-3 is identical as embodiment 2, and difference is only that:
1,3- propylene glycol in the formula of upper 1 embodiment 2 of table is changed into the glycerol of equivalent by comparative example 1；
1,3- propylene glycol in the formula of upper 1 embodiment 2 of table is changed into the dipropylene glycol of equivalent by comparative example 2；
Comparative example 3 replaces bright string coccus/radish root tunning filtrate (1.852%) in the formula of upper 1 embodiment 2 of table
It is changed to the combination of 1,2- hexylene glycol (0.483%) and parahydroxyacet-ophenone (0.536%).
Wherein, in comparative example 3 D phase materials the preparation method comprises the following steps: by 1,2- hexylene glycol is added to containing 1,3-PD
In beaker, it is heated to 65-70 DEG C, after temperature is stablized, parahydroxyacet-ophenone is slowly added to while stirring, stirs into later saturating
Then prescribed liquid is down to 40.5-44.5 DEG C to solution temperature in 2) and is added.
Evaluation on probation is carried out to sample obtained by embodiment 1-3 and comparative example 1-3, major embodiment is in use to biology
Facial mask carries out several aspects such as sticking nature, comfort level, bacterium colony, stability, sensitive skin subject's use feeling and evaluates.
(1) sensory evaluation, the measurement of physicochemical property pH value
Sensory evaluation measuring method are as follows: the sample of biological facial mask is issued to 20 testers and compares use.Tester
Applying film is carried out according to specified application method when member uses sample, each sample respectively uses one week, and tester is according to oneself sense
Feel and carry out sensory evaluation, ten point system is taken in scoring, and 1 point worst, and 10 points best.Tester carries out sense organ according to the feeling of oneself and comments
Ten point system is taken in valence, scoring, and 1 point worst, and 10 points best.
Physical and chemical pH value measuring method are as follows: by biological facial mask essence sample by Essence: it is surveyed after water=1:9 dilution proportion
The pH value of biological facial mask essence.
Sensory evaluation and pH value measurement result are as shown in table 3 below.
Table 3: Analyses Methods for Sensory Evaluation Results
Conclusion: the experimental result of upper table 3 is analyzed it is found that the product of embodiment 1-3 makes relative to comparative example 1-3
It is more preferable with sense.
(2) stability
The formula of embodiment 2, comparative example 1 and comparative example 2 is investigated at 45 DEG C, 25~27 DEG C and -18 DEG C, whether is liquid
There is layering, be precipitated, whether viscosity changes, and it is spoiled whether smell has, and whether liquid has color change.Stability Determination result is such as
Shown in the following table 4~6.
Table 4: the stability result of embodiment 2
Table 5: the stability result of comparative example 1
Table 6: the stability result of comparative example 2
Conclusion: after the experimental result of You Shangbiao 4, table 5 and table 6 is it is found that the sample of comparative example 1 places 90 days, -18 DEG C of environment
In sample bottom there is the transparent ring of light.The heat-resisting color of 2 sample of comparative example is unstable, liquid after placing 90 days in 45 DEG C of environment
Body color burn turns yellow.And the product of the embodiment of the present invention 2 sample either at room temperature or 45 DEG C, -18 DEG C is all relatively more steady
It is fixed.
(3) antimicrobial preservation efficacy detection
By VP-T-0002 " milky lotion inhibitory effect measures scheme " 00 edition, antimicrobial preservation effect of embodiment 2 is detected,
Measurement item includes that the 0th day, the 7th day, the 14th day and the 28th day bacteria living Counting alive microbial and yeast and mold are deposited
Viable count measurement, as a result as shown in table 7 below.
Specific implementation method are as follows: take 20g test sample into the sterile blue cover glass bottle of 100ml.1g test sample quantity of microorganism inoculated
It is 105Cfu or 106Cfu bacteria suspension carries out survival Counting alive microbial 0 day, 7 days, 14 days, 28 days, it is desirable that the fungi at the 7th day
90% is reduced, bacterium reduces by 99.9%, and bacterium number continues to decline in 28 days.
Table 7: 2 preservative efficacy of embodiment detection
Conclusion: 7 experimental result of You Shangbiao is examined it is found that according to VP-T-0002 " milky lotion inhibitory effect measures scheme " 00 edition
Antimicrobial preservation effect of embodiment 2 is surveyed, the results show that test organisms meets acceptable standard, test result reaches expected
As a result.
It is main according to antimicrobial preservation effect of European Pharmacopoeia EP7.0 (5.1.3 antimicrobial preservation effect) detection comparative example 3
Want the bacterium of detection bacterium (pseudomonas aeruginosa, staphylococcus aureus), yeast and saccharomycete (candida albicans and aspergillus niger)
Sum is fallen, as a result as shown in table 8 below.
Table 8: the preservative efficacy detection of comparative example 3
Conclusion: 8 experimental result of You Shangbiao is it is found that special according to European standard EP7.05.1.3 antimicrobial preservation efficacy detection sheet
The preservative efficacy for the product that sharp comparative example 3 obtains, also reaches standard requirements as the result is shown.
(4) multiple skin irritation test
Embodiment 2 is detected according to " cosmetics safety technical specification " version skin irritation in 2015/corrosion test method
Skin irritation, predominantly detect biological facial mask be repeatedly applied to test skin (new zealand rabbit) after, to mammal skin office
Whether irritating portion's effect or corrosiveness and its degree, test result be as shown in table 9 below.
Table 9: biological facial mask embodiment 2 is to the multiple skin irritation test result of new zealand rabbit
Conclusion: by the test result of table 9 it is found that according to " cosmetics safety technical specification " version skin irritation in 2015/
Corrosion test judgment criteria, the multiple skin irritation test of biological facial mask of embodiment 2 are non-stimulated to skin irritatin intensity
Property.
(5) human body irritation test
For the thermal sensation routinely encountered in facial mask use process, scratchiness and tingling sensation, we are to embodiment 2 and comparative example
3 biological facial mask has carried out the comparison of human body irritation test, and specific implementation method is as follows:
1) subject for selecting 10 sensitive skin, cleans full face；
2) 5 left faces of subject use 2 facial mask of embodiment, and right face uses 3 facial mask of comparative example；Other 5 right faces use real
2 facial mask of example is applied, left face uses 3 facial mask of comparative example；Using 15 minutes, from calorimetric sense, scratchiness, tingling sensation；
3) compare the number of two facial mask sense of discomfort.
Test results are shown in figure 1 by sensitive skin subject.
It can be seen that scratchiness, the shouting pain of the facial mask of embodiment 2 from the sensitive skin subject use feeling column diagram of Fig. 1
Feel obviously lighter than comparative example 3, the system milder of the facial mask of embodiment 2 is more suitable for using in biological facial mask.
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance
Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or
Implicitly include at least one this feature.In the description of the present invention, the meaning of " plurality " is at least two, such as two, three
It is a etc., unless otherwise specifically defined.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show
The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example
Point is included at least one embodiment or example of the invention.In the present specification, schematic expression of the above terms are not
It must be directed to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be in office
It can be combined in any suitable manner in one or more embodiment or examples.In addition, without conflicting with each other, the skill of this field
Art personnel can tie the feature of different embodiments or examples described in this specification and different embodiments or examples
It closes and combines.
Although the embodiments of the present invention has been shown and described above, it is to be understood that above-described embodiment is example
Property, it is not considered as limiting the invention, those skilled in the art within the scope of the invention can be to above-mentioned
Embodiment is changed, modifies, replacement and variant.
Claims (22)
1. a kind of cosmetic composition characterized by comprising
Water, allantoin, 1,3- propylene glycol, macromolecular Sodium Hyaluronate, purple ball algae extract, glycine betaine, algae extract, saccharomycete
Lysis object extract, gentian root extract, lavandulae flos water, bright string coccus/radish root tunning filtrate, small molecule are transparent
Matter acid sodium, ethoxy urea and hydrolysis heartsease extract, the molecular weight of the macromolecular Sodium Hyaluronate are not less than 10kDa,
The molecular weight of the micromolecule hyaluronic acid sodium is less than 10kDa,
Wherein:
The parts by weight of the water are 60-90,
The parts by weight of the allantoin are 0.01-1,
The parts by weight of the 1,3-PD are 2-8,
The parts by weight of the macromolecular Sodium Hyaluronate are 0.01-1,
The parts by weight of the micromolecule hyaluronic acid sodium are 0-1,
The parts by weight of the purple ball algae extract are 0.01-2,
The parts by weight of the ethoxy urea are 0-1,
The parts by weight of the hydrolysis heartsease extract are 0-1,
The parts by weight of the glycine betaine are 0.1-5,
The parts by weight of the algae extract are 0.1-4,
The parts by weight of the saccharomycete lysis object extract are 0.01-1,
The parts by weight of the gentian root extract are 0.01-1,
The parts by weight of the lavandulae flos water are 0.5-3, and
Stating string coccus/radish root tunning filtrate parts by weight clearly is 1-4.
2. cosmetic composition according to claim 1, which is characterized in that
The parts by weight of the water are 68.56-89.8,
The parts by weight of the allantoin are 0.01-0.5,
The parts by weight of the 1,3-PD are 2.35-7.65,
The parts by weight of the macromolecular Sodium Hyaluronate are 0.01-0.80,
The parts by weight of the micromolecule hyaluronic acid sodium are 0-0.5,
The parts by weight of the purple ball algae extract are 0.05-1.36,
The parts by weight of the ethoxy urea are 0-0.83,
The parts by weight of the hydrolysis heartsease extract are 0.3-0.72,
The parts by weight of the glycine betaine are 0.5-4.2,
The parts by weight of the algae extract are 0.5-3.3,
The parts by weight of the saccharomycete lysis object extract are 0.01-0.80,
The parts by weight of the gentian root extract are 0.03-0.76,
The parts by weight of the lavandulae flos water are 0.8-2.5, and
Stating string coccus/radish root tunning filtrate parts by weight clearly is 1.5-3.
3. cosmetic composition according to claim 1, which is characterized in that
The parts by weight of the water are 75-88,
The parts by weight of the allantoin are 0.01-0.1,
The parts by weight of the 1,3-PD are 2.35-6.8,
The parts by weight of the macromolecular Sodium Hyaluronate are 0.1-0.8,
The parts by weight of the micromolecule hyaluronic acid sodium are 0-0.1,
The parts by weight of the purple ball algae extract are 0.05-1.36,
The parts by weight of the ethoxy urea are 0-0.83,
The parts by weight of the hydrolysis heartsease extract are 0.3-0.68,
The parts by weight of the glycine betaine are 0.5-4.2,
The parts by weight of the algae extract are 0.5-3.3,
The parts by weight of the saccharomycete lysis object extract are 0.05-0.80,
The parts by weight of the gentian root extract are 0.03-0.76,
The parts by weight of the lavandulae flos water are 0.85-2.12, and
Stating string coccus/radish root tunning filtrate parts by weight clearly is 1.5-3.
4. cosmetic composition according to claim 1, which is characterized in that the allantoin is mentioned in the form of being dissolved in water
It supplies.
5. cosmetic composition according to claim 4, which is characterized in that the weight ratio of the allantoin and water is
(0.01-1): (60-90).
6. cosmetic composition according to claim 4, which is characterized in that the weight ratio of the allantoin and water is
(0.01-0.5): (68.56-89.8).
7. cosmetic composition according to claim 4, which is characterized in that the weight ratio of the allantoin and water is
(0.01-0.1): (75-88).
8. cosmetic composition according to claim 1, which is characterized in that the macromolecular Sodium Hyaluronate and optional
Micromolecule hyaluronic acid sodium is provided in the form of being scattered in 1,3- propylene glycol.
9. cosmetic composition according to claim 8, which is characterized in that the macromolecular Sodium Hyaluronate, small molecule
The weight ratio of Sodium Hyaluronate and 1,3- propylene glycol is (0.01-1): (0-1): (2-8).
10. cosmetic composition according to claim 8, which is characterized in that the macromolecular Sodium Hyaluronate, small molecule
The weight ratio of Sodium Hyaluronate and 1,3- propylene glycol is (0.01-0.80): (0-0.5): (2.35-7.65).
11. cosmetic composition according to claim 8, which is characterized in that the macromolecular Sodium Hyaluronate, small molecule
The weight ratio of Sodium Hyaluronate and 1,3- propylene glycol is (0.1-0.8): (0-0.1): (2.35-6.8).
12. a kind of cosmetic composition characterized by comprising
The water of 87.303 weight %,
The allantoin of 0.032 weight %,
The 1,3-PD of 4.5 weight %,
The macromolecular Sodium Hyaluronate of 0.32 weight %,
The micromolecule hyaluronic acid sodium of 0.012 weight %,
The purple ball algae extract of 0.85 weight %,
The ethoxy urea of 0.43 weight %,
The hydrolysis heartsease extract of 0.46 weight %,
The glycine betaine of 1.6 weight %,
The algae extract of 1.8 weight %,
The saccharomycete lysis object extract of 0.113 weight %,
The gentian root extract of 0.12 weight %,
The lavandulae flos water of 0.93 weight %, and
The bright string coccus of 1.53 weight %/radish root tunning filtrate；
Wherein, the molecular weight of the macromolecular Sodium Hyaluronate is not less than 10kDa, the molecular weight of the micromolecule hyaluronic acid sodium
Less than 10kDa.
13. a kind of cosmetic composition characterized by comprising
The water of 84.509 weight %,
The allantoin of 0.056 weight %,
The 1,3-PD of 5.19 weight %,
The macromolecular Sodium Hyaluronate of 0.443 weight %,
The micromolecule hyaluronic acid sodium of 0.024 weight %,
The purple ball algae extract of 0.99 weight %,
The ethoxy urea of 0.49 weight %,
The hydrolysis heartsease extract of 0.51 weight %,
The glycine betaine of 1.95 weight %,
The algae extract of 2.1 weight %,
The saccharomycete lysis object extract of 0.235 weight %,
The gentian root extract of 0.391 weight %,
The lavandulae flos water of 1.26 weight %, and
The bright string coccus of 1.852 weight %/radish root tunning filtrate；
Wherein, the molecular weight of the macromolecular Sodium Hyaluronate is not less than 10kDa, the molecular weight of the micromolecule hyaluronic acid sodium
Less than 10kDa.
14. a kind of cosmetic composition characterized by comprising
The water of 78.43 weight %,
The allantoin of 0.021 weight %,
The 1,3-PD of 6.25 weight %,
The macromolecular Sodium Hyaluronate of 0.465 weight %,
The micromolecule hyaluronic acid sodium of 0.048 weight %,
The purple ball algae extract of 1.05 weight %,
The ethoxy urea of 0.75 weight %,
The hydrolysis heartsease extract of 0.62 weight %,
The glycine betaine of 3.3 weight %,
The algae extract of 2.6 weight %,
The saccharomycete lysis object extract of 0.726 weight %,
The gentian root extract of 0.73 weight %,
The lavandulae flos water of 2.05 weight %, and
The bright string coccus of 2.96 weight %/radish root tunning filtrate；
Wherein, the molecular weight of the macromolecular Sodium Hyaluronate is not less than 10kDa, the molecular weight of the micromolecule hyaluronic acid sodium
Less than 10kDa.
15. a kind of method for preparing cosmetic composition characterized by comprising
Allantoin and water are subjected to the first mixed processing, to obtain the first mixture；
First mixture is heated, it is described heat treatment be 80.5-84.5 DEG C at a temperature of carry out 3-
7min；
First mixture after heat treatment is subjected to the first cooling treatment, the temperature after first cooling treatment is
50.5-54.5℃；
By first mixture and macromolecular Sodium Hyaluronate and optional micromolecule hyaluronic acid after the first cooling treatment
The mixed solution of sodium carries out the second mixed processing, to obtain the second mixture；
Second mixture is subjected to the second cooling treatment, the temperature after second cooling treatment is 40.5-44.5 DEG C；
By second mixture and purple ball algae extract, glycine betaine, algae extract, saccharomycete lysis after the second cooling treatment
Object extract, gentian root extract, lavandulae flos water, bright string coccus/radish root tunning filtrate and optional hydroxyl second
Base urea and/or hydrolysis heartsease extract carry out third mixed processing, to obtain the cosmetic composition；
Wherein, the mixed solution of the macromolecular Sodium Hyaluronate and optional micromolecule hyaluronic acid sodium includes that macromolecular is transparent
Matter acid sodium, 1,3-PD and optional micromolecule hyaluronic acid sodium,
The parts by weight of the water are 60-90, and the parts by weight of the allantoin are 0.01-1, and the parts by weight of the 1,3-PD are
2-8, the parts by weight of the macromolecular Sodium Hyaluronate are 0.01-1, and the parts by weight of the micromolecule hyaluronic acid sodium are 0-1, institute
The parts by weight for stating purple ball algae extract are 0.01-2, and the parts by weight of the ethoxy urea are 0-1, the hydrolysis heartsease extract
Parts by weight be 0-1, the parts by weight of the glycine betaine are 0.1-5, and the parts by weight of the algae extract are 0.1-4, the yeast
The parts by weight of bacterium lysis object extract are 0.01-1, and the parts by weight of the gentian root extract are 0.01-1, the lavender
The parts by weight of Hua Shui are 0.5-3, and stating string coccus/radish root tunning filtrate parts by weight clearly is 1-4；
Wherein, the molecular weight of the macromolecular Sodium Hyaluronate is not less than 10kDa, the molecular weight of the micromolecule hyaluronic acid sodium
Less than 10kDa.
16. according to the method for claim 15, which is characterized in that the parts by weight of the water are 68.56-89.8, the urine
The parts by weight of Bursin are 0.01-0.5, and the parts by weight of the 1,3-PD are 2.35-7.65, the macromolecular Sodium Hyaluronate
Parts by weight be 0.01-0.80, the parts by weight of the micromolecule hyaluronic acid sodium are 0-0.5, the weight of the purple ball algae extract
Amount part is 0.05-1.36, and the parts by weight of the ethoxy urea are 0-0.83, and the parts by weight of the hydrolysis heartsease extract are
0.3-0.72, the parts by weight of the glycine betaine are 0.5-4.2, and the parts by weight of the algae extract are 0.5-3.3, the saccharomycete
The parts by weight of lysis object extract are 0.01-0.80, and the parts by weight of the gentian root extract are 0.03-0.76, described to smoke
The parts by weight of clothing showy flowers of herbaceous plants water are 0.8-2.5, and stating string coccus/radish root tunning filtrate parts by weight clearly is 1.5-3.
17. according to the method for claim 15, which is characterized in that the parts by weight of the water are 75-88, the allantoin
Parts by weight are 0.01-0.1, and the parts by weight of the 1,3-PD are 2.35-6.8, the weight of the macromolecular Sodium Hyaluronate
Part is 0.1-0.8, and the parts by weight of the micromolecule hyaluronic acid sodium are 0-0.1, and the parts by weight of the purple ball algae extract are
0.05-1.36, the parts by weight of the ethoxy urea are 0-0.83, and the parts by weight of the hydrolysis heartsease extract are 0.3-
0.68, the parts by weight of the glycine betaine are 0.5-4.2, and the parts by weight of the algae extract are 0.5-3.3, the saccharomycete lysis
The parts by weight of object extract are 0.05-0.80, and the parts by weight of the gentian root extract are 0.03-0.76, the lavender
The parts by weight of Hua Shui are 0.85-2.12, and stating string coccus/radish root tunning filtrate parts by weight clearly is 1.5-3.
18. a kind of facial mask, which is characterized in that by the described in any item cosmetic compositions of claim 1~14 or according to right
It is required that the cosmetic composition of 15~17 described in any item method preparations is prepared.
19. facial mask according to claim 18, which is characterized in that further comprise: membrane of biological fibers；
Wherein, the membrane of biological fibers is impregnated with the described in any item cosmetic compositions of claim 1~14 or according to right
It is required that the cosmetic composition of 15~17 described in any item method preparations.
20. a kind of method for preparing facial mask characterized by comprising
By the described in any item cosmetic compositions of claim 1~14 or according to the described in any item sides of claim 15~17
The cosmetic composition of method preparation carries out cooling treatment, to obtain the facial mask.
21. according to the method for claim 20, which is characterized in that the temperature after the cooling treatment is not higher than 40 DEG C.
22. according to the method for claim 20, which is characterized in that further comprise: membrane of biological fibers is infiltrated in cooling
The described in any item cosmetic compositions of claim 1~14 that treated are described in any item according to claim 15~17
In the cosmetic composition of method preparation.
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| CN109381352A (en) * | 2018-11-15 | 2019-02-26 | 乳源南岭好山好水化妆品有限公司 | A kind of cosmetic composition, preparation method and its spraying |
| CN113425663A (en) * | 2021-08-18 | 2021-09-24 | 皖西学院 | Preparation method of dendrobium flower soybean skin-beautifying mask |
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Effective date of registration: 20200526 Address after: 512700 East sunshine industry of milk Town, Ruyuan County, Shaoguan, Guangdong Co-patentee after: Dongguan dongyangguang cosmetics R & D Co.,Ltd. Patentee after: RUYUAN NANLING HAOSHAN HAOSHUI COSMETICS CO.,LTD. Address before: 512700 East sunshine industry of milk Town, Ruyuan County, Shaoguan, Guangdong Co-patentee before: SUNSHINE LAKE PHARMA Co.,Ltd. Patentee before: RUYUAN NANLING HAOSHAN HAOSHUI COSMETICS Co.,Ltd. |
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Denomination of invention: Cosmetic composition and preparation method thereof Effective date of registration: 20220906 Granted publication date: 20190614 Pledgee: Zhuhai Huarun bank Limited by Share Ltd. Pledgor: RUYUAN NANLING HAOSHAN HAOSHUI COSMETICS CO.,LTD.|Dongguan dongyangguang cosmetics R & D Co.,Ltd. Registration number: Y2022980014569 |
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Date of cancellation: 20231109 Granted publication date: 20190614 Pledgee: Zhuhai Huarun bank Limited by Share Ltd. Pledgor: RUYUAN NANLING HAOSHAN HAOSHUI COSMETICS CO.,LTD.|Dongguan dongyangguang cosmetics R & D Co.,Ltd. Registration number: Y2022980014569 |
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