CN107951775A - A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract and preparation method thereof - Google Patents
A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract and preparation method thereof Download PDFInfo
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- CN107951775A CN107951775A CN201711384791.2A CN201711384791A CN107951775A CN 107951775 A CN107951775 A CN 107951775A CN 201711384791 A CN201711384791 A CN 201711384791A CN 107951775 A CN107951775 A CN 107951775A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
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Abstract
The present invention relates to a kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract and preparation method thereof, the plants herb toothpaste includes according to the parts by weight of raw material：0.01~10 part of kudzu root extract, 0.01~10 part of Herba Eupatorii extract, 0.005~0.5 part of Thymol, 0.01~5.0 part of xylitol, 15~45 parts of rubbing agent, 15~65. parts of moisturizer, 0.5~2 part of adhesive, 1~5 part of foaming agent, 0.05~0.25 part of sodium benzoate, 0.08~0.4 part of Sucralose, 0.5~2. part of essence, 4.95~27.48 parts of water.The present invention has anti-halitosis antibacterial, fresh breath, mothproof permanent tooth, anti-inflammatory analgesic, treatment canker sore and other effects, can effectively prevent and treat periodontal disease, and using safer.
Description
Technical field
The invention belongs to oral care implement field, more particularly, to a kind of plant containing pueraria lobata and Herba Eupatorii extract
Herbaceous toothpaste and preparation method thereof.
Background technology
With the improvement of people ' s living standards with the gradual rationalization of consumption idea.In oral care implement, consumer gets over
More to focus on the safe and harmless property of product, people gradually start to be keen to seek natural, nontoxic raw material application
In toothpaste.The Chinese herbal medicine toothpaste that Chinese herbal medicine extract or raw material are added obtained by toothpaste is increasingly subject in recent years
The accreditation and purchase of consumers in general.Publication No. CN201611028437 disclose a kind of honeysuckle compound herbaceous toothpaste and its
Preparation method, its active matter component are：Honeysuckle 33.4%, chrysanthemum 22.2%, green tea 22.2%, peppermint 22.2%；
CN201610714333 discloses a kind of toothpaste of extract containing herbal essences, its active matter component is：3 parts of humulus grass, mulberry leaf 1
Part, 1 part of Rosa roxburghii Tratt.Plants herb component taste number is too many contained by herbaceous toothpaste described in above-mentioned patent, causes component composition complicated, makes
Original content is lower with regard to limited active constituent content in toothpaste, causes practical effect to weaken.And various plants draft into
Divide to be applied in toothpaste at the same time and can produce large effect to the mouthfeel of toothpaste since taste is different, and be not easy to be connect by consumer
By.
Pueraria lobata is plants of the genus, and tcm clinical practice is included in through the common medicine that expels pathogenic wind from the body surface, the Ministry of Public Health of China
Arrive in " be both food and medicine " register.《Compendium of Materia Medica》In also mention " pueraria lobata is Yangming Channel medicine, it is simultaneous enter the spleen channel, spleen
Main muscle ".
Pueraria lobata is removed containing abundant high-quality starch, essential amino acid (lysine, methionine, phenylalanine, different bright ammonia
Acid, leucine etc.) and micro- (selenium, zinc, manganese, germanium etc.) is outside, also containing kudzu root flavone, pueraria polysaccharide, Puerarin, soybean
The Flavonoid substances such as glycosides, daidzein.Bring down a fever, promote the production of body fluid to quench thirst with expelling pathogenic factors from muscles and skin, Shengyang Zhixie, treatment fever caused by exogenous pathogens, thirsty, macula
The multiple pharmacological effect such as impermeable, hot dysentery, splenasthenic diarrhea, hypertension, headache Xiang Qiang, antitumor.For having a headache caused by hypertension,
The symptoms such as dizziness, tinnitus have obvious curative effects.There is certain inhibitory action to bacterium, fungi.
Publication No. CN106376814A《A kind of Wild Pueraria plant beverage and its processing technology》, Publication No.
CN106418541A《A kind of Wild Pueraria oral liquid and preparation method thereof》, Publication No. CN105769986A《A kind of pueraria lobata nozzle
Chew piece and its application》, Publication No. CN106615474A《The preparation method and kudzu root tea of a kind of kudzu root tea》Disclose pueraria lobata
Application of many effects in drink, chewable tablets, oral liquid.
Eupatorium is the drying overground part of composite family (Compositae) plant eupatorium (Eupatorium fortune Turcz)
Point, for the herbaceos perennial of dietotherapeutic.It is used as medicine first recorded in《Sheng Nong's herbal classic》, " fragrant thoroughwort, acrid flavour, puts down, main Li Shui
Road, kills disease due to noxious agents produced by various parasites, eliminating turbid pathogens, long term usage QI invigorating, not always, being proficient in the law of natural movement." main component that contains of eupatorium is volatile oil compound, oil
In containing p- poly- cymene (p-cymene), nerol ethyl ester (neryl ace-tate), 5- methyl thymol ethers (5-
Methyl thymolether), fumaric acid (Fumaricacid), butanedioic acid (Succinic acid), mannitol
(Mannitol) etc..With prevention and treatment turbi damp obstructing in middle-JIAO, gastral cavity ruffian evil of vomitting, sweet, halitosis in mouth, polysialia, summer-heat and damp characterization, damp-warm syndrome
From the beginning of, burnout of generating heat, the effect of waiting disease uncomfortable in chest of not relaxing.Medicine of being amusing of removing dampness by means of aromatics is commonly used as a kind of tcm clinical practice, is had long
Medication history.Application also has the function that antibacterial, anti-inflammatory, treatment canker sore in the oral cavity.
Publication No. CN101103759《Agastache rugosa eupatorium fortunei chewing gum》, Publication No. CN1282538《A kind of eupatorium beverage》、
Publication No. CN101314019《Buccal tablet of fortune eupatorium herb》, Publication No. CN105558524A《Eupatorium effervescent tablet》, Publication No.
CN106511125A《Eupatorium compound solid-state essential oil and application thereof and its capsule preparation method thereof》, asked for solving halitosis, dry etc.
Topic.
The either single extract of this two Plant Extracts or composition are there is not yet apply on toothpaste
Report.
The content of the invention
A kind of the defects of the purpose of the invention is to overcome the prior art, there is provided plant containing pueraria lobata and Herba Eupatorii extract
Herbaceous toothpaste.The herbaceous toothpaste has the work(such as anti-halitosis antibacterial, fresh breath, mothproof permanent tooth, anti-inflammatory analgesic, treatment canker sore
Effect, can effectively prevent and treat periodontal disease.
Another object of the present invention is to provide a kind of system of the above-mentioned plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract
Preparation Method.
Above-mentioned purpose of the present invention is achieved by the following technical programs：
A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, includes according to raw material weight number：Kudzu root extract
0.01~10 part, 0.01~10 part of Herba Eupatorii extract, 0.005~0.5 part of Thymol, 0.01~5 part of xylitol, sodium benzoate
0.05~0.25 part, 0.08~0.4 part of Sucralose, 15.0~45 parts of rubbing agent, 15~65 parts of moisturizer, adhesive 0.5~2
Part, 1.0~5 parts of foaming agent, 0.50~2 part of essence, 4.95~27.48 parts of water.
Preferably, the preparation method of the kudzu root extract is：Take 50~100g of pueraria lobata to crush, add ethanol 250mL
Extraction solvent, 48~72h of soak at room temperature, stirs 1 time every 6~12h, is filtered under diminished pressure, and is concentrated to dryness after recycling ethanol, obtains pueraria lobata and carry
Take thing.
Preferably, the preparation method of the Herba Eupatorii extract is：300~500g of eupatorium is loaded into steam distillation extraction
In device, water is added to distill 6~12h, liquid is concentrated to dryness, and collection obtains Herba Eupatorii extract.
Preferably, the rubbing agent is one or more of calcium carbonate, silica or calcium monohydrogen phosphate.
Preferably, the moisturizer is one or more of sorbierite, glycerine or polyethylene glycol.
It is further preferable that the molecular weight of the polyethylene glycol is 400~600.
Preferably, the adhesive is one or more of xanthans, sodium alginate, cellulose gum or carragheen；
Preferably, the foaming agent is laruyl alcohol sodium sulfovinate, sodium lauroyl sarcosine or cocamidopropyl propyl amide beet
One or more of alkali.
Preferably, the essence is one or more of for minty note, the fragrance of a flower or fruity, the fragrance of a flower is jasmin,
Flores aurantii is fragrant or orchid is fragrant, and the fruity is lemonene, strawberry is fragrant, "Hami" melon is fragrant or honey peach is fragrant.
The preparation method of the above-mentioned plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, including step in detail below：
S1. deionized water, Sucralose, sodium benzoate, moisturizer, kudzu root extract, Herba Eupatorii extract, xylitol are mixed
Close and add in aqua pot, stirring is made aqueous solution and sucks Manufacturing medicine extract machine；
S2. Manufacturing medicine extract machine is added after mixing rubbing agent, adhesive, 20~25min of agitation grinding is uniform to lotion, synchronous true
Empty deaeration；
S3. foaming agent, Thymol, essence are sequentially added into Manufacturing medicine extract machine, 10~15min of agitation grinding, deaeration, is made and contains
The plants herb toothpaste of pueraria lobata, Herba Eupatorii extract
Compared with prior art, the invention has the advantages that：
1. plants herb toothpaste of the present invention has anti-halitosis antibacterial, fresh breath, mothproof permanent tooth, anti-inflammation hemostasia, treatment mouth
Chamber ulcer and other effects, can effectively prevent and treat periodontal disease.
2. the present invention is had safer, green using the plants herb component kudzu root extract and Herba Eupatorii extract of integration of drinking and medicinal herbs
The feature of color, more meets Vehicles Collected from Market and consumer appeal.
Embodiment
Present disclosure is further illustrated with reference to specific embodiment, but should not be construed as limiting the invention.
Unless otherwise specified, the conventional means that technological means used in embodiment is well known to those skilled in the art.Except non-specifically
Illustrate, reagent that the present invention uses, method and apparatus is the art conventional reagent, method and apparatus.
Embodiment 1
A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, includes according to the parts by weight of composition of raw materials：Pueraria lobata
0.9 part of extract, 8 parts of Herba Eupatorii extract, 0.005 part of Thymol, 0.3 part of xylitol, rubbing agent (mass ratio 8:1 carbon
Sour calcium and silica) 38 parts, moisturizer (mass ratio 25:3:3 sorbierite, glycerine and Macrogol 600) 23 parts, gluing
Agent (mass ratio 4:3 cellulose gum and xanthans) 0.75 part, 2 parts of foaming agent (laruyl alcohol sodium sulfovinate), sodium benzoate
0.25 part, 0.15 part of Sucralose, 0.5 part of essence (mint aroma), 26.145 parts of water.
The preparation process of above-mentioned plants herb toothpaste includes step in detail below：
The first step, by deionized water, Sucralose, sodium benzoate, moisturizer, kudzu root extract, Herba Eupatorii extract, xylose
Alcohol is sequentially added in aqua pot in the ratio, and stirring is made aqueous solution and sucks Manufacturing medicine extract machine；
Wherein, the preparation method of kudzu root extract is：Take 50~100g of pueraria lobata to crush, add 95% ethanol 250mL conducts
Extraction solvent, 48~72h of soak at room temperature, stirs 1 time every 6~12h, is filtered under diminished pressure, and recycles ethanol, and liquid is concentrated to dryness, and obtains Pueraria lobota
Root extract.
The preparation method of Herba Eupatorii extract is：300~500g of eupatorium is fitted into steam distillation extractor, adds water to distill
6~12h, liquid are concentrated to dryness, and collect Herba Eupatorii extract.
Second step, adds Manufacturing medicine extract machine after in proportion mixing rubbing agent, adhesive, high-speed stirred grinds 20~25min extremely
Lotion is uniform, synchronous vacuum defoamation；
3rd step, sequentially adds Manufacturing medicine extract machine by foaming agent, Thymol, essence in proportion, and high-speed stirred grinding 10~
15min, deaeration, is made plants herb toothpaste.
4th step, filling after Physico-chemical tests qualification, packaging.
Embodiment 2
A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, includes according to the parts by weight of composition of raw materials：Pueraria lobata
0.01 part of extract, 10.0 parts of Herba Eupatorii extract, 0.015 part of Thymol, 1.3 parts of xylitol, rubbing agent (silica) 22
Part, moisturizer (mass ratio 12:3:5 sorbierite, glycerine and polyethylene glycol 400) 45 parts, adhesive (mass ratio 9:2
Cellulose gum and carragheen) 0.5 part, foaming agent (mass ratio 3:1 laruyl alcohol sodium sulfovinate and sodium lauroyl sarcosine) 3.5
Part, 0.05 part of sodium benzoate, 0.25 part of Sucralose, 1.5 parts of essence (jasmine fragrance), 15.875 parts of water.
Embodiment 3
A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, includes according to the parts by weight of composition of raw materials：Pueraria lobata
2.0 parts of extract, 4.5 parts of Herba Eupatorii extract, 0.05 part of Thymol, 2.5 parts of xylitol, 15 parts of rubbing agent (silica),
Moisturizer (mass ratio 15:2 sorbierite and glycerine) 65 parts, adhesive (mass ratio 8:3 cellulose gum and alginic acid
Sodium) 0.9 part, foaming agent (mass ratio 2:1 laruyl alcohol sodium sulfovinate and sodium lauroyl sarcosine) 2.5 parts, sodium benzoate
0.10 part, 0.08 part of Sucralose, 1.7 parts of essence (flores aurantii odor type), 5.67 parts of water.
Embodiment 4
A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, includes according to the parts by weight of composition of raw materials：Pueraria lobata
3.7 parts of extract, 5.5 parts of Herba Eupatorii extract, 0.10 part of Thymol, 3.6 parts of xylitol, 35 parts of rubbing agent (silica),
Moisturizer (mass ratio 30:4 sorbierite and glycerine) 20 parts, adhesive (mass ratio 3:1 cellulose gum and carragheen)
0.9 part, foaming agent (mass ratio 7:3 sodium lauroyl sarcosine and Cocoamidopropyl betaine) 5.0 parts, sodium benzoate
0.15 part, 0.10 part of Sucralose, 1.0 parts of essence (orchid odor type), 24.95 parts of water.
Embodiment 5
A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, includes according to the parts by weight of composition of raw materials：Pueraria lobata
1.5 parts of extract, 7 parts of Herba Eupatorii extract, 0.35 part of Thymol, 4 parts of xylitol, rubbing agent (mass ratio 1:2 silica
And calcium monohydrogen phosphate) 26 parts, moisturizer (mass ratio 27:2 sorbierite and glycerine) 42 parts, adhesive (mass ratio 7:3 Huang
Virgin rubber and carragheen) 0.9 part, foaming agent (mass ratio 8:3 laruyl alcohol sodium sulfovinate and sodium lauroyl sarcosine) 1 part, benzene
0.2 part of sodium formate, 0.27 part of Sucralose, 0.9 part of essence (lemon flavor), 15.88 parts of water.
Embodiment 6
A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, includes according to the parts by weight of composition of raw materials：Pueraria lobata
5.2 parts of extract, 3.0 parts of Herba Eupatorii extract, 0.26 part of Thymol, 3.5 parts of xylitol, rubbing agent (mass ratio 3:1 phosphorus
Sour hydrogen calcium and silica) 40 parts, moisturizer (mass ratio 8:3:1 sorbierite, polyethylene glycol 400 and Macrogol 600)
27 parts, adhesive (mass ratio 2:5 sodium alginate and xanthans) 1.5 parts, foaming agent (mass ratio 5:2 laruyl alcohol sulphur
Acid esters sodium and Cocoamidopropyl betaine) 4.0 parts, 0.13 part of sodium benzoate, 0.30 part of Sucralose, ("Hami" melon is fragrant for essence
Type) 2.0 parts, 13.11 parts of water.
Embodiment 7
A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, includes according to the parts by weight of composition of raw materials：Pueraria lobata
6.5 parts of extract, 2.1 parts of Herba Eupatorii extract, 0.17 part of Thymol, 2.2 parts of xylitol, rubbing agent (mass ratio 4:1 phosphorus
Sour hydrogen calcium and silica) 31.0 parts, moisturizer (mass ratio 9:2:2 sorbierite, polyethylene glycol 400 and glycerine) 25.0
Part, adhesive (mass ratio 1:5:3 sodium alginate, cellulose gum and xanthans) 1.5 parts, foaming agent (mass ratio 9:4
Laruyl alcohol sodium sulfovinate and Cocoamidopropyl betaine) 1.7 parts, 0.20 part of sodium benzoate, 0.35 part of Sucralose, essence
1.80 parts of (honey peach odor type), 27.48 parts of water.
Embodiment 8
A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, includes according to the parts by weight of composition of raw materials：Pueraria lobata
7.0 parts of extract, 1.3 parts of Herba Eupatorii extract, 0.46 part of Thymol, 0.01 part of xylitol, rubbing agent (mass ratio 6:5
Calcium monohydrogen phosphate and silica) 40.0 parts, moisturizer (mass ratio 12:1 sorbierite and polyethylene glycol 400) 35.0 parts, glue
Glutinous 2.0 parts of agent (cellulose gum), 3.0 parts of foaming agent (Cocoamidopropyl betaine), 0.18 part of sodium benzoate, Sucralose
0.40 part, 1.2 parts of essence (lemon-mint odor type), 9.45 parts of water.
Embodiment 9
A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, includes according to the parts by weight of composition of raw materials：Pueraria lobata
8.5 parts of extract, 0.55 part of Herba Eupatorii extract, 0.50 part of Thymol, 4.7 parts of xylitol, rubbing agent (mass ratio 5:2
Calcium carbonate and calcium monohydrogen phosphate) 45 parts, moisturizer (mass ratio 8:1 sorbierite and Macrogol 600) 23 parts, adhesive (matter
Amount is than being 6:2:1 cellulose gum, carragheen and sodium alginate) 1.0 parts, foaming agent (mass ratio 5:3 sodium lauroyl sarcosines
And Cocoamidopropyl betaine) 4.3 parts, 0.22 part of sodium benzoate, 0.35 part of Sucralose, essence (flores aurantii jasmine fragrance)
1.5 parts, 10.38 parts of water.
Embodiment 10
A kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, includes according to the parts by weight of composition of raw materials：Pueraria lobata
10.0 parts of extract, 0.01 part of Herba Eupatorii extract, 0.03 part of Thymol, 5.0 parts of xylitol, rubbing agent (mass ratio 7:3
Calcium carbonate and calcium monohydrogen phosphate) 37 parts, moisturizer (mass ratio 6:1 sorbierite and Macrogol 600) 15 parts, adhesive it is (yellow
Virgin rubber) 1.5 parts, 2.8 parts of foaming agent (sodium lauroyl sarcosine), 0.22 part of sodium benzoate, 0.38 part of Sucralose, essence (grass
Certain kind of berries odor type) 1.3 parts, 26.76 parts of water.
Embodiment 11
1. physical and chemical index and stability test and appraisal
The plants herb toothpaste containing pueraria lobata, Herba Eupatorii extract in embodiment 1-10 is detected by GB8372, as a result
Be qualification, stability is placed 30~45 days under the conditions of 45 DEG C, lotion do not return it is thick, do not separate, regardless of water, it is not fuel-displaced, constant
Discoloration taste.
2. mouthfeel is tested and assessed
Choose 50 subjects and carry out mouthfeel test and appraisal, sample is white pipe, and whole subjects are carried out the side of brushing teeth by numbering A
Method instructs.Subject disposably brushes teeth each sample using unified toothbrush.It is salubrious that foam is experienced after brush, is easily removed
Oral peculiar smell and tooth stain, do not stimulate, good without obvious Chinese herbal medicine taste, overall mouth feeling experience.
3. canker sore prevention effect is tested and assessed
The plants herb toothpaste of above-mentioned preparation, can effectively kill harmful oral bacteria, effectively respectively using once sooner or later daily
The mouth diseases such as anti-treating dental ulcer, oral mucosa irritation.Specifically used example effects are as follows：
Patient of the selection with canker sore is applied, and patient totally 240, at 15~45 years old age, man 120, female 120
Example.
The Chinese herbal toothpaste that all patients are prepared using above-described embodiment 4 is brushed teeth, and once in the morning and once at night, does not add it
Its medicine.After 2 weeks, observe and evaluate curative effect.The standard of curative effect evaluation：
Cure：Symptom disappear or mostly disappear.
Effectively：Symptom largely improves.
It is invalid：Effective standard or exacerbation of symptoms person are not reached.
As a result after week, in 240 canker sore patients, 218, effective 17, invalid 5 are cured.
All users are without obvious side effect.In all healing persons, recidivist 4 in three months.
Illustrate the toothpaste of the present invention, there is good prevention effect to canker sore, it is without side-effects, control difficulty in relapse after healing.
Representative instance clock, man, 25 years old, likes eating meat, has canker sore, and with halitosis (morning is especially serious), make
It can not be alleviated with ordinary toothpaste.The toothpaste prepared using embodiment 4 is brushed teeth, daily morning and evening respectively once, after 1 week, symptom
Considerably reduce, canker sore is cured, and the gas peculiar smell of exhalation is considerably reduced, is continuing with 1 week, the gas of exhalation is no different substantially
Taste, significant effect.
Representative instance Tan, female, 32 years old, often gets angry, canker sore, deep disturbed.The toothpaste prepared using embodiment 4
Brush teeth, daily morning and evening respectively once, after 4 days, canker sore recovery from illness, is continuing with 10 days.Paid a return visit after three months, there are no mouth
Chamber ulcer recurrence, significant effect.
Above-described embodiment is the preferable embodiment of the present invention, but embodiments of the present invention and from above-described embodiment
Limitation, other any Spirit Essences without departing from the present invention with made under principle change, modification, replacement, combine and simplification,
Equivalent substitute mode is should be, is included within protection scope of the present invention.
Claims (10)
1. a kind of plants herb toothpaste containing pueraria lobata and Herba Eupatorii extract, it is characterised in that the plants herb toothpaste presses raw material
Parts by weight include：0.01~10 part of kudzu root extract, 0.01~10 part of Herba Eupatorii extract, Thymol 0.005~0.5
Part, 0.01~5 part of xylitol, 0.05~0.25 part of sodium benzoate, 0.08~0.4 part of Sucralose, 15.0~45 parts of rubbing agent,
15~65 parts of moisturizer, 0.5~2 part of adhesive, 1.0~5 parts of foaming agent, 0.5~2 part of essence, 4.95~27.48 parts of water.
2. the plants herb toothpaste according to claim 1 containing pueraria lobata and Herba Eupatorii extract, it is characterised in that the Pueraria lobota
The preparation method of root extract is：50~100g of pueraria lobata is taken to crush, addition ethanol 250mL Extraction solvents, soak at room temperature 48~
72h, stirs 1 time every 6~12h, is filtered under diminished pressure, and is concentrated to dryness after recycling ethanol, obtains kudzu root extract.
3. the plants herb toothpaste according to claim 1 containing pueraria lobata and Herba Eupatorii extract, it is characterised in that the pendant
The preparation method of blue extract is：300~500g of eupatorium is fitted into distillation extractor, adds water to distill 6~12h, liquid concentration
To doing, collection obtains Herba Eupatorii extract.
4. the plants herb toothpaste according to claim 1 containing pueraria lobata and Herba Eupatorii extract, it is characterised in that described rubs
Liniment is one or more of calcium carbonate, silica or calcium monohydrogen phosphate.
5. the plants herb toothpaste according to claim 1 containing pueraria lobata and Herba Eupatorii extract, it is characterised in that the guarantor
Humectant is one or more of sorbierite, glycerine or polyethylene glycol.
6. the plants herb toothpaste according to claim 5 containing pueraria lobata and Herba Eupatorii extract, it is characterised in that described is poly-
The molecular weight of ethylene glycol is 400~600.
7. the plants herb toothpaste according to claim 1 containing pueraria lobata and Herba Eupatorii extract, it is characterised in that the glue
Glutinous agent is one or more of xanthans, sodium alginate, cellulose gum or carragheen.
8. the plants herb toothpaste according to claim 1 containing pueraria lobata and Herba Eupatorii extract, it is characterised in that the hair
Infusion is one or more of laruyl alcohol sodium sulfovinate, sodium lauroyl sarcosine or Cocoamidopropyl betaine.
9. the plants herb toothpaste according to claim 1 containing pueraria lobata and Herba Eupatorii extract, it is characterised in that the essence
For one or more of minty note, the fragrance of a flower or fruity, the fruit that the fragrance of a flower is jasmin, flores aurantii is fragrant or orchid is fragrant, described
Perfume is lemonene, strawberry is fragrant, "Hami" melon is fragrant or honey peach is fragrant.
10. according to the preparation side of plants herb toothpaste of claim 1~9 any one of them containing pueraria lobata and Herba Eupatorii extract
Method, it is characterised in that including step in detail below：
S1. deionized water, Sucralose, sodium benzoate, moisturizer, kudzu root extract, Herba Eupatorii extract, xylitol are mixed and added
Enter in aqua pot, stirring is made aqueous solution and sucks Manufacturing medicine extract machine；
S2. Manufacturing medicine extract machine is added after mixing rubbing agent, adhesive, 20~25min of agitation grinding is uniform to lotion, and synchronous vacuum takes off
Bubble；
S3. foaming agent, Thymol, essence are sequentially added into Manufacturing medicine extract machine, 10~15min of agitation grinding, deaeration, is made and contains pueraria lobata
With the plants herb toothpaste of Herba Eupatorii extract.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113197812A (en) * | 2021-06-17 | 2021-08-03 | 湖北仙之灵食品有限公司 | Production process of toothpaste with tooth cleaning, anti-inflammatory and bactericidal functions |
| CN113398049A (en) * | 2021-07-16 | 2021-09-17 | 深圳市西马龙科技有限公司 | Toothpaste containing antibacterial and anti-inflammatory components and preparation method thereof |
| CN113520957A (en) * | 2021-09-01 | 2021-10-22 | 乐草元生物医药研究院(广州)有限公司 | Chinese herbal medicine toothpaste formula for gingivitis and gingival atrophy and preparation method thereof |
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| CN105193688A (en) * | 2015-10-07 | 2015-12-30 | 梅照付 | Toothpaste for removing bad breath |
| CN105581967A (en) * | 2016-03-07 | 2016-05-18 | 李晓晓 | Preparation method of formula of toothpaste capable of treating periodontitis |
| CN105769726A (en) * | 2016-03-07 | 2016-07-20 | 李晓晓 | Toothpaste formula capable of treating periodontitis |
| CN107184465A (en) * | 2017-05-25 | 2017-09-22 | 成都万雅迪生物科技有限公司 | A kind of halitosis-removing toothpaste |
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| CN105193688A (en) * | 2015-10-07 | 2015-12-30 | 梅照付 | Toothpaste for removing bad breath |
| CN105581967A (en) * | 2016-03-07 | 2016-05-18 | 李晓晓 | Preparation method of formula of toothpaste capable of treating periodontitis |
| CN105769726A (en) * | 2016-03-07 | 2016-07-20 | 李晓晓 | Toothpaste formula capable of treating periodontitis |
| CN107184465A (en) * | 2017-05-25 | 2017-09-22 | 成都万雅迪生物科技有限公司 | A kind of halitosis-removing toothpaste |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113197812A (en) * | 2021-06-17 | 2021-08-03 | 湖北仙之灵食品有限公司 | Production process of toothpaste with tooth cleaning, anti-inflammatory and bactericidal functions |
| CN113398049A (en) * | 2021-07-16 | 2021-09-17 | 深圳市西马龙科技有限公司 | Toothpaste containing antibacterial and anti-inflammatory components and preparation method thereof |
| CN113520957A (en) * | 2021-09-01 | 2021-10-22 | 乐草元生物医药研究院(广州)有限公司 | Chinese herbal medicine toothpaste formula for gingivitis and gingival atrophy and preparation method thereof |
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Application publication date: 20180424 |