CN107951468A - A kind of laminating adhesive composition and its preparation and application for being used to obtain skin physiology state - Google Patents

A kind of laminating adhesive composition and its preparation and application for being used to obtain skin physiology state Download PDF

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Publication number
CN107951468A
CN107951468A CN201711154753.8A CN201711154753A CN107951468A CN 107951468 A CN107951468 A CN 107951468A CN 201711154753 A CN201711154753 A CN 201711154753A CN 107951468 A CN107951468 A CN 107951468A
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CN
China
Prior art keywords
laminating adhesive
adhesive composition
skin
physiology state
skin physiology
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CN201711154753.8A
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Chinese (zh)
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CN107951468B (en
Inventor
刘建欣
方兆华
冯小玲
孙永
何海鸥
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Zhuhai Easycare Technology Co Ltd
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Zhuhai Easycare Technology Co Ltd
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Priority to CN201711154753.8A priority Critical patent/CN107951468B/en
Publication of CN107951468A publication Critical patent/CN107951468A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/442Evaluating skin mechanical properties, e.g. elasticity, hardness, texture, wrinkle assessment

Abstract

The invention discloses a kind of laminating adhesive composition for being used to obtain skin physiology state, it is characterised in that including following components:Film forming agent 6 35%, filler 1 20%, grease 0.01 4%, auxiliary agent 0.1 10%, surplus is solvent;The laminating adhesive composition coating of the present invention is on the skin, it can be obtained after dry solidification including information such as dermatoglyph, pore, greases, and it can accurately analyze and obtain skin physiology state, its is of low cost, easy to use, pain is not had during sampling, is suitable for developing the skin preparation for external use of personalized customization.

Description

A kind of laminating adhesive composition and its preparation and application for being used to obtain skin physiology state
Technical field
The invention belongs to skin preparations for extenal use technical field, more particularly to a kind of laminating adhesive group for being used to obtain skin physiology state Compound and its preparation method and application.
Background technology
Dermatoglyph refers to the texture graphics that human skin surface occurs, also known as dermatoglyph, and the skin of the mankind is by epidermis and true Skin is formed.Papilla is raised to epidermis, forms many marshallings, parallel mammillary line, this line is also known as ridge line.Have on ridge line The opening of many sweat glands.The ridge line of projection mutually forms concave ditch again.These concavo-convex textures just constitute the skin of human body Texture.The dermatoglyph of human body it is existing it is individual treat the opposite sex, and have the stability of height.
With age, the gradual aging of skin, the depth down of dermatoglyph, therewith because of aging or overexposure or flesh Wrinkle will occur in meat repeating motion.Dermatoglyph is transcribed by skin laminating adhesive, the pore, sebum and elasticity of skin can be observed Etc. index, so as to assess the health status of skin.
At present, skin physiology state collection method on the market is typically to prepare dermatoglyph sample using silica gel laminating adhesive, is used The skin detection instrument of specialty directly gathers skin image.Preparing dermatoglyph sample using silica gel laminating adhesive, there are drying time length, observation The shortcomings of index few (as only observed texture and the sulci of skin depth);Using skin detection instrument by external image capture device come Collection dermatoglyph data transfer to computer analyzes it, and the image capture device build that specialty is stablized is big, it has not been convenient to takes Band, although and mobile terminal (smart mobile phone) take pictures conveniently, for light, photographic quality equistability poor repeatability.
Therefore, it is necessary to a kind of non-invasive detection methods of quick and convenient and of low cost skin physiology state, contained The sample of skin physiology status information, by carrying out directly observing to sample or further quantitatively being divided using graphical analysis instrument Analysis, obtains the skin physiology status information of personalization, instructs exploitation to customize formula, so as to fulfill personalized accurate skin care.
The content of the invention
In view of the problems of the existing technology, it is used to obtain answering for skin physiology state the object of the present invention is to provide a kind of Film composition and its preparation method and application.By the way that on the skin, after film-forming, laminating adhesive composition coating is obtained skin The information such as skin texture, sebum, pore, and then observe, analyze, judge skin physiology state.
To achieve these goals, the present invention uses following technical scheme:
A kind of laminating adhesive composition for being used to obtain skin physiology state, including following components:
Film forming agent 6-35%,
Filler 1-20%,
Auxiliary agent 0.1-10%,
Surplus is solvent.
The laminating adhesive composition is made according to the following steps:
(1) film forming agent, filler are added sequentially in solvent, are warming up to 70-90 DEG C, stirred evenly;
(2) room temperature is cooled to, auxiliary agent is added, stirs evenly.
Preferably, the auxiliary agent is selected from grease, thickener, emulsifying agent, anti-sensitizer and at least one of the preservatives.
Preferably, the laminating adhesive composition for being used to obtain skin physiology state includes following group by weight percentage Point:
Preferably, the film forming agent is selected from polyvinyl alcohol, polyvinylpyrrolidone, acrylic acid (ester) analog copolymer, propylene At least one in sour (ester) class/ethylhexy acrylate copolymer, styrene/acrylic (ester) analog copolymer, polyurethane -35 Kind.
Preferably, the filler is selected from titanium dioxide, kaolin, zinc oxide, talcum powder, diatomite, mica powder, silica, two Silica, bamboo charcoal powder, silica flour, Attagel, bentonite, organobentonite, volcanic ash, hot spring soil, mud, atlapulgite, water At least one of pyroxene powder, magnesium carbonate, montmorillonite.
Preferably, the thickener in cellulose, aluminium-magnesium silicate, xanthan gum, carbomer, carragheen at least one Kind.
Preferably, the grease be selected from Dormant oils, olive oil, jojoba oil, Sweet Almond Oil, caprylic/capric triglyceride, Ethylhexyl palmitate, Nexbase 2004, isohexadecane, sunflower (HELIANTHUS ANNUUS) seed oil, palmitic acid isopropyl At least one of ester, C12-15 alcohol benzoic ethers, dimethyl silicone polymer, ring five dimethyl silicone polymer.
Preferably, the emulsifying agent is selected from the stearate of polyglycereol -3, Natrulon H-10 oleate, the laurate of polyglycereol -4 Ester, monoglyceride, Tween-60, cocoyl Portugal glycosides, PEG-100 stearates, ceteareth -6, ceteareth - 25th, at least one of Phosphoric acid monohexadecyl ester potassium.
Preferably, the anti-sensitizer is selected from least one of allantoin, dipotassium glycyrrhizinate, purslane extract.
Preferably, the preservative is selected from least one of Phenoxyethanol, imidazolidinyl urea, DMDM hydantoin.
Preferably, the solvent in water, glycerine, propane diols, butanediol, glycerin polyether -26, alcohol at least one Kind.
The preparation method of the above-mentioned laminating adhesive composition for being used to obtain skin physiology state, comprises the following steps:
(1) film forming agent, thickener and filler are added sequentially in solvent, 70-90 DEG C are warming up in 10-20min, stirring Uniformly, mixing speed 200-300r/min, it is spare to obtain A phases;
(2) grease, emulsifying agent are mixed and are warming up to 70-80 DEG C, it is spare to obtain B phases;
(3) B is added to homogeneous 2 minutes in A phases, is cooled to 40-50 DEG C, it is equal to add anti-sensitizer, preservative stirring and dissolving It is even, you can.
The application method of the above-mentioned laminating adhesive combination for being used to obtain skin physiology state, skin is coated in by the laminating adhesive composition On skin, it is 0.05-0.5mm to be preferably coated with thickness, after dry solidification, forms laminating adhesive.Laminating adhesive composition can not coat it is blocked up, It can cause to be difficult to drying, and then laminating adhesive can not be transferred to and sticked;Laminating adhesive composition can not coat it is excessively thin, can cause cannot understand turn Record dermatoglyph and cannot show sebum secretion situation completely.
By laminating adhesive appearance profile amplifying camera obtained above and computer is inputted, through computer image analysis system, is seen Examine the information such as analyzing skin texture, fat secretion, pore size and number.
Laminating adhesive obtained above can also directly be visually observed, obtain skin physiology status information.
The composition of the present invention can also be matched with the suite of tools for transcribing dermatoglyph.
The suite of tools for being used to transcribe dermatoglyph, including laminating adhesive frame, peritonaeum patch, wherein being set among the laminating adhesive frame There is a hole.
Preferably, the laminating adhesive external member further includes cubing.
Preferably, a length of 10-30mm of the laminating adhesive frame, width 10-30mm, thickness 0.1-0.5mm.
Preferably, the hole on the laminating adhesive frame is square, circular, diamond shape or rectangle.
It is further preferred that the size in hole is 5-25mm on the laminating adhesive frame.For example, when laminating adhesive hole is circular, its is straight Footpath is 5-25mm;When laminating adhesive hole is square, diamond shape or rectangle, its length of side is 5-25mm.
Preferably, the material of the laminating adhesive frame includes but not limited to PE, PVC.It is further preferred that the one of the laminating adhesive frame Side is equipped with adhesive linkage, laminating adhesive frame is pasted on the skin.Laminating adhesive frame is used for when smearing laminating adhesive composition, passes through laminating adhesive Laminating adhesive composition is smeared in hole on frame, and it is excessive or too small to play the laminating adhesive avoided the formation of, and influences the effect of microexamination, And play the role of positioning.
Preferably, the laminating adhesive patch includes sequentially connected transparent thin film layer, adhesive linkage and protective layer.
Peritonaeum patch security, it is nontoxic, can directly contact skin.
It is further preferred that the 180 degree Bao of the adhesive linkage is from Qiang Du≤5.0N/25mm, no more than 10N/25mm;Bond Layer it is sticky excessive, have pain when tearing, damage skin;Viscosity is too small, can not paste and shift laminating adhesive, or even shift Make laminating adhesive damaged in journey.The material of the transparent thin film layer includes but not limited to polyethylene, polypropylene, glassine paper, poly- to benzene two Formic acid glycol ester, polyolefin etc..
It is further preferred that the protective layer is divided into 2 parts, laminating adhesive can be completely covered in center section.It is it is further preferred that described Protective layer is release liners, oilpaper etc..
Preferably, the cubing is equipped with a hole, wherein, the hole in cubing is greater than or equal to the hole on laminating adhesive frame, with profit In the dermatoglyph that microexamination is transcribed into complete laminating adhesive.
It is further preferred that the long 75-77mm of the cubing, wide 24-26mm and thickness are 0.5-5mm.The cubing On hole be arranged on the middle and upper part of cubing.It is further preferred that the material of the cubing is PE, PC or PVC etc..
It is highly preferred that the afterbody of the cubing is designed to rounded corner (as shown in Figure 8), skin is overlayed on available for overcoating will be smeared On skin, avoid polluting.
A kind of method for detecting skin physiology state, comprises the following steps:
(1) after cleaning skin, dry;
(2) laminating adhesive frame is pasted on the skin;
(3) laminating adhesive composition is smeared on the skin from the hole of laminating adhesive frame, and smeared uniform;
(4) after laminating adhesive of tearing frame, laminating adhesive composition is maintained the original state and stop 8-15min on skin, to being completely dried;
(5) laminating adhesive is taken to paste, peritonaeum of tearing sticks the center section of protective layer, by the adhesive linkage of exposed portion and laminating adhesive pair Standard is simultaneously pasted onto in laminating adhesive, presses lightly on laminating adhesive patch, laminating adhesive is pasted with laminating adhesive and is fitted closely;
(5) slowly tear from top to bottom and be stained with the laminating adhesive patch of laminating adhesive;
(6) laminating adhesive of tearing sticks remaining protective layer, laminating adhesive is aligned with the hole in cubing, and laminating adhesive patch is pasted onto cubing On, amplify and observed under 10--100 power microscopes.
Preferably, the intersection point at centre position alignment horizontal distance canthus 5mm with nose on the left of laminating adhesive frame is made.
It should be noted that to avoid changing expression during laminating adhesive dry solidification, otherwise will impact analysis result.
Sebum is secreted in sebaceous glands, and the lipid produced with horn cell and the sweat being secreted in sweat gland exist Skin surface is combined into one layer of invisible film, is called natural cortex film or natural moisture preserving film.After the present invention is by face cleaning Dry moisture and coat laminating adhesive composition immediately, the sebaceous glands at coated position, which remains unchanged, understands sebum secreted, the place more than sebum secretion Protrusion can be produced, so make relative to laminating adhesive at produce depression, so as to observe the circular hole that falls under the microscope.
Amplify evaluation criteria:
(1) 10 times of observation dermatoglyphs are amplified:Sulci of skin is obvious, and skin mound is arranged with neat shape (triangle), and full Protuberance, illustrates that dermatoglyph situation is good, skin becomes clear, surface is moistened with tension force and elasticity, as shown in Fig. 5 (a);Sulci of skin is shallow, Unobvious, skin mound is misaligned, does not swell, flat situation, illustrates poor dermatoglyph, obscure, dry tack free, without tension force And elasticity, as shown in Fig. 5 (b);
(2) in 50 times of Microscopic observation pores:Texture intersection point is small, unobvious, illustrates that pore is small, and quantity is few, and skin is smoothly thin It is greasy, as shown in Fig. 6 (a);Texture intersection point is more, obvious, illustrates that pore is big, quantity is more, then skin surface is uneven, does not open Power, easily takes off adornment, as shown in Fig. 6 (b);
(3) observation of amplification 100, laminating adhesive upper concave hole is more and big, illustrates that sebum secretion is vigorous, and pore is thick, and skin is easily long Acne, as shown in Fig. 7 (a);Laminating adhesive upper concave hole moderate number, illustrates that sebum secretion is more moderate, and skin oil and fat is more balanced, such as schemes Shown in 7 (b);Laminating adhesive upper concave hole is few and small, illustrates that sebum secretion is few, dry skin, easy itch, or even has pain, such as Fig. 7 (c) It is shown.
Beneficial effects of the present invention:
(1) laminating adhesive composition of the invention coating on the skin, can be transcribed including dermatoglyph, hair after dry solidification The information such as hole, grease, and then analyze and judge skin physiology state;
(2) laminating adhesive composition of the invention is of low cost, easy to use;Pain is not had during sampling;
(3) laminating adhesive composition using the present invention, can provide the technology for judging skin physiology state, it can be high Precision quickly judges skin condition;
(4) laminating adhesive composition of the invention is the skin preparation for external use for being suitable for providing customization of individual character.
Brief description of the drawings
Fig. 1 is the top view of laminating adhesive frame;
Fig. 2 is the structure diagram for the peritonaeum patch for being stained with laminating adhesive;
Fig. 3 is the schematic diagram of protective layer;
Fig. 4 is the schematic diagram of cubing;
Fig. 5 a-5b are the micrograph of dermatoglyph;
Fig. 6 a-6b are the micrograph of skin pore;
Fig. 7a-7c is the micrograph that skin sebum secretes situation;
Fig. 8 is the side view of cubing;
Fig. 9 a-9b are respectively that volunteer A and volunteer B uses the laminating adhesive micrograph before personalized product;
Figure 10 a-10b are respectively that volunteer A and volunteer B uses the laminating adhesive micrograph after personalized product.
Embodiment
The embodiment of the present invention is described in detail below in conjunction with attached drawing and example.It should be appreciated that this Locate described embodiment to be merely to illustrate and explain the present invention, be not intended to limit the invention.
Embodiment 1
A kind of laminating adhesive composition for being used to obtain skin physiology state, including following raw material by weight percentage:
Polyvinyl alcohol 8%, acrylic acid (ester) analog copolymer 15%, kaolin 13%, Dormant oils 2%, cellulose 0.02%, gathers The stearate of glycerine -3 2%, anti-sensitizer 2%, preservative 0.3%, water surplus.
Preparation method:Polyvinyl alcohol, acrylic acid (ester) analog copolymer, cellulose, kaolin are sequentially added in water, stirred 78 DEG C are warming up to, homogeneous 2 minutes, is cooled to 45 DEG C, addition Dormant oils, the stearate of polyglycereol -3, anti-sensitizer, preservative stirring are molten Solution is uniform, you can.
Embodiment 2
A kind of laminating adhesive composition for being used to obtain skin physiology state, including following raw material by weight percentage:
Polyvinyl alcohol 5%, styrene/acrylic (ester) analog copolymer 20%, titanium dioxide 20%, olive oil 4%, magnesium silicate Aluminium 1%, the laurate of polyglycereol -4 0.01%, anti-sensitizer 4%, preservative 0.5%, water surplus.
Preparation method:Polyvinyl alcohol, styrene/acrylic (ester) analog copolymer, aluminium-magnesium silicate, titanium dioxide are sequentially added In water, stirring is warming up to 80 DEG C, homogeneous 2 minutes, is cooled to 45 DEG C, add olive oil, the laurate of polyglycereol -4, anti-sensitizer, Preservative stirring and dissolving is uniform, you can.
Embodiment 3
A kind of laminating adhesive composition for being used to obtain skin physiology state, including following raw material by weight percentage:
Acrylic acid (ester) class/ethylhexy acrylate copolymer 15%, acrylic acid (ester) analog copolymer 1%, zinc oxide 1%, ethylhexyl palmitate 0.01%, xanthan gum 0.05%, the laurate of polyglycereol -4 4%, anti-sensitizer 0.1%, preservative 0.5%, glycerine surplus.
Preparation method:Acrylic acid (ester) class/ethylhexy acrylate copolymer, acrylic acid (ester) analog copolymer, xanthan gum, Zinc oxide is sequentially added in glycerine, and stirring is warming up to 75 DEG C, homogeneous 2 minutes, is cooled to 45 DEG C, add ethylhexyl palmitate, The laurate of polyglycereol -4, anti-sensitizer, preservative stirring and dissolving are uniform, you can.
Embodiment 4
The laminating adhesive composition 2g prepared by embodiment 2 is taken, in appointed part, uniformly smears on the skin, is allowed in skin Upper formation thickness about 0.05-0.5mm or so.Keep skin condition place 15 minutes, ask user try not change use portion The posture of position, otherwise can impact analysis as a result, after the laminating adhesive composition dry solidification, form laminating adhesive sample, tear.
By the appearance profile amplifying camera of laminating adhesive and computer is inputted, it is near through computer image analysis system, observation laminating adhesive The height of its skin-side surface protrusion, measures the depth of texture and wrinkle;The quantity of the nearly its skin-side surface grease of laminating adhesive is observed, is obtained The situation of the fat secretion of skin;Count the size and number of nearly skin side pore.
Embodiment 5
The laminating adhesive composition of the present invention is matched with the suite of tools for transcribing dermatoglyph
Referring to Fig. 1-3, a kind of laminating adhesive external member for being used to transcribe dermatoglyph, including laminating adhesive frame 1, laminating adhesive 2, peritonaeum patch 3, inspection Tool 4, wherein being equipped with a hole 11 among the laminating adhesive frame.1 a length of 15mm of laminating adhesive frame, width 15mm, thickness 0.5mm;It is multiple The length of side in hole is 11mm on film frame;The material of the laminating adhesive frame is PVC;The side of the laminating adhesive frame is equipped with adhesive linkage.It is described multiple Film 2 is that the laminating adhesive composition of embodiment 2 coats on the skin, and dry solidification is formed after 15min, it is mounted in hose;It is described Peritonaeum thickness is 0.1mm.The peritonaeum patch 3 includes sequentially connected transparent thin film layer 31, adhesive linkage 32 and protective layer 33;Its In, protective layer 33 is divided into 2 parts, and a part is center section, and laminating adhesive can be completely covered in it.The 180 degree stripping of the adhesive linkage It is 6N/25mm from intensity.The cubing 4 is equipped with a hole 41, wherein, the hole in cubing is slightly larger than the hole 11 on laminating adhesive frame.Institute State a length of 76mm of cubing 4, width 25mm, thickness 1.5mm.
The application method of the above-mentioned laminating adhesive external member for being used to transcribe dermatoglyph, comprises the following steps:
(1) after cleaning skin, dry;
(2) side that laminating adhesive frame is equipped with to adhesive linkage is pasted on the skin, makes centre position alignment on the left of laminating adhesive frame horizontal At canthus 5mm with the intersection point of nose;
(3) coating agent is expressed in the hole on laminating adhesive frame, and is smeared uniformly, or taken in right amount with the afterbody of cubing Coating agent, uniformly coats coating agent along the hole in laminating adhesive frame on the skin;
(4) after laminating adhesive of tearing frame, coating agent is maintained the original state and stop 15min on skin, to being completely dried, form laminating adhesive;
(5) laminating adhesive patch 3 is taken, it is after the center section of protective layer 33 is torn, the adhesive linkage being exposed and laminating adhesive 2 is right Standard, and be pasted onto in laminating adhesive, after fitting closely the two, so that laminating adhesive is completely transferred to peritonaeum and sticks;
(6) slowly tear from top to bottom and be stained with the laminating adhesive patch of laminating adhesive;
(7) laminating adhesive of tearing sticks remaining protective layer, laminating adhesive is aligned with the hole in cubing, and laminating adhesive patch is pasted onto cubing On, 10-100 times of amplification is observed.
Embodiment 6
Volunteer 20 between selection age 16-50 Sui, is sampled using 5 method of embodiment, amplifies 100 times of observations.Take it In 2 volunteers, the laminating adhesive micrograph of volunteer A and volunteer B are respectively Fig. 9 a and Fig. 9 b:
Laminating adhesive skin oil and fat test chart such as Fig. 9 a and Fig. 9 b understands that it is few to volunteer the fat secretion of A, and aspiration B greases are excessively It is vigorous;The skin preparation for external use of the personalized customization of volunteer A is directed to, mainly by with the addition of jojoba oil, hyalomitome The moisture and oil of sour sodium enhancing skin;In addition, by adding ceramide skin water and oil balance can be made improving sebum film, increase The self-protection function of strong skin.
The skin preparation for external use of the personalized customization of volunteer B is directed to, mainly by adding PCA zinc oil-control compositions, Sebum secretion amount is adjusted, the activity of esterified ferment can be reduced, it is i.e. effective in the short time.In addition there are potent moisture-keeping efficacy and suppression Bacterium performance.
To aspiration A, the volunteer B difference following products of personalized customization:
The formula of volunteer's A personalized customization products A is as shown in table 1:
The formula of 1 product A of table
The formula of volunteer's B personalized customization products B is as shown in table 2:
The formula of 2 product B of table
Volunteer A, after B has cleaned face sooner or later daily, takes corresponding personalized customization product 5g, is respectively applied to face. Sampled after 28 days using 5 method of embodiment, amplify 100 times of observations.The laminating adhesive microexamination of volunteer A and B is taken to see Figure 10 a respectively With Figure 10 b.
From the laminating adhesive skin oil and fat test chart test result of Figure 10 a and Figure 10 b, by using the skin of personalized customization After skin external preparation, the skin oil and fat content increase of volunteer A, close to normally;The skin oil and fat secretion of volunteer B is reduced, and is connect It is near normal.
It can be seen from the above that the laminating adhesive composition of the present invention, can accurately analyze the skin physiology state that obtains, secondly be adapted to first , can be effectively by using the preparation for external application to skin of personalized customization for developing the skin preparation for external use of personalized customization Personalized skin care is carried out for individual, reaches optimal skin effect.
The above is only the preferred embodiment of the present invention, it is noted that for those of ordinary skill in the art, Without departing from the concept of the premise of the invention, various modifications and improvements can be made, these belong to the guarantor of the present invention Protect scope.

Claims (10)

1. a kind of be used to obtain the laminating adhesive composition of skin physiology state, it is characterised in that including it is following by weight percentage Component:
Film forming agent 6-35%,
Filler 1-20%,
Auxiliary agent 0.1-10%,
Surplus is solvent.
It is made according to following steps:
(1) film forming agent, filler are added sequentially in solvent, 20-90 DEG C of temperature, stirs evenly;
(2) room temperature is cooled to, auxiliary agent is added, stirs evenly.
2. the laminating adhesive composition according to claim 1 for being used to obtain skin physiology state, it is characterised in that the auxiliary agent Selected from grease, thickener, emulsifying agent, anti-sensitizer and at least one of the preservatives.
3. the laminating adhesive composition according to claim 1 or 2 for being used to obtain skin physiology state, it is characterised in that including Following components:
4. the laminating adhesive composition according to claim 1 for being used to obtain skin physiology state, it is characterised in that the film forming Agent is selected from polyvinyl alcohol, polyvinylpyrrolidone, acrylic acid (ester) analog copolymer, acrylic acid (ester) class/ethylhexyl acrylate At least one of copolymer, styrene/acrylic (ester) analog copolymer, polyurethane -35.
5. the laminating adhesive composition according to claim 1 for being used to obtain skin physiology state, it is characterised in that the filler Selected from titanium dioxide, kaolin, zinc oxide, talcum powder, diatomite, mica powder, silica, silica, bamboo charcoal powder, silica flour, silicon In magnesia, bentonite, organobentonite, volcanic ash, hot spring soil, mud, atlapulgite, hectorite powder, magnesium carbonate, montmorillonite It is at least one.
6. the laminating adhesive composition according to claim 2 for being used to obtain skin physiology state, it is characterised in that the thickening Agent is selected from least one of cellulose, aluminium-magnesium silicate, xanthan gum, carbomer, carragheen.
7. the laminating adhesive composition according to claim 2 for being used to obtain skin physiology state, it is characterised in that the grease Selected from Dormant oils, olive oil, jojoba oil, Sweet Almond Oil, caprylic/capric triglyceride, ethylhexyl palmitate, the hydrogenation poly- last of the ten Heavenly stems Alkene, isohexadecane, sunflower seed oil, isopropyl palmitate, C12-15 alcohol benzoic ethers, dimethyl silicone polymer, ring five poly- two At least one of methylsiloxane.
8. the laminating adhesive composition according to claim 2 for being used to obtain skin physiology state, it is characterised in that the emulsification Agent is selected from the stearate of polyglycereol -3, Natrulon H-10 oleate, the laurate of polyglycereol -4, monoglyceride, Tween-60, cocoyl In Portugal's glycosides, PEG-100 stearates, ceteareth -6, ceteareth -25, Phosphoric acid monohexadecyl ester potassium extremely Few one kind.
9. the laminating adhesive composition according to claim 2 for being used to obtain skin physiology state, it is characterised in that the antiallergic Agent is selected from least one of allantoin, dipotassium glycyrrhizinate, purslane extract;The preservative is selected from Phenoxyethanol, imidazoles At least one of ureine, hydantoins;The solvent is selected from water, glycerine, propane diols, butanediol, glycerin polyether -26, wine At least one of essence.
10. the application for being used to obtain the laminating adhesive composition of skin physiology state according to any one of claim 1-9, its It is characterized in that, is suitable for providing the skin preparation for external use of customization of individual character.
CN201711154753.8A 2017-11-20 2017-11-20 Compound film composition for acquiring skin physiological state and preparation and application thereof Active CN107951468B (en)

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CN85107871A (en) * 1984-10-01 1986-06-10 托克尔·英格马尔·费希尔 Hypersensitivity test means
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