CN107929481A - A kind of production method of tortoise deer life plate medicine - Google Patents

A kind of production method of tortoise deer life plate medicine Download PDF

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Publication number
CN107929481A
CN107929481A CN201711432376.XA CN201711432376A CN107929481A CN 107929481 A CN107929481 A CN 107929481A CN 201711432376 A CN201711432376 A CN 201711432376A CN 107929481 A CN107929481 A CN 107929481A
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chinese yam
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王保健
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/58—Reptiles
    • A61K35/586—Turtles; Tortoises, e.g. terrapins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/62—Nymphaeaceae (Water-lily family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

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  • Health & Medical Sciences (AREA)
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Abstract

The present invention relates to a kind of production method of tortoise deer life plate medicine, include the components of following parts by weight：Component A：15-30 parts of radix pseudostellariae, 30-60 parts of radix astragali, 15-30 parts of Angelica sinensis, 10-15 parts of arillus longan；B component：15-30 parts of Poria cocos, 15-30 parts of Chinese yam, 10-25 parts of Rhizoma Atractylodis Macrocephalae, 10-30 parts of jujube；Component C：10-15 parts of tortoise-shell glue, 10-15 parts of deer horn glue, 15-30 parts of lotus seeds, 15-30 parts of Chinese yam rhizome.Tri- kinds of components of A, B, C are worn into pulvis by the preparation method of Chinese medicine composition of the present invention respectively, and after crossing 80-100 mesh sieves, tri- kinds of components of A, B, C are by weight 1:1:1 proportioning loads capsule.Medical expense of the present invention is low, Small side effects, and curative effect is stablized, and is effectively improved bleeding.

Description

A kind of production method of tortoise deer life plate medicine
Technical field
The present invention relates to a kind of process for preparing medicine for treating Idiopathic Thrombocytopenic Purpura, and in particular to a kind of tortoise The production method that deer gives birth to plate medicine.
Technical background
Idiopathic Thrombocytopenic Purpura（ITP）It is with bleeding and peripheral blood decrease of platelet, Significance of Megakaryocyte Number It is normal or increase and be the common hemorrhagic disease that mainly shows with dysmaturity.This disease is a kind of since patient's body produces Resist itself platelet antibody, cause platelet life span to shorten, destroy the autoimmune disease that excessive, quantity is reduced to pathological characters Disease.ITP is divided to acute and chronic two kinds, is difficult to discriminate between, both etiology and pathogenesis and lapses to far different in disease early stage.Children 80% For acute（AITP）, asexuality difference, two season of winter in spring susceptible disease, majority has virus infection history, is self-limited disease, generally recognizes To be acute viral infection latter innate immune reaction, once pathogeny is removed, disease was fully recovered at 6 ~ 12 months.And adult 95% It is chronic type above（CITP）, the ratio between men and women about 1:3, it is considered that belong to one kind of autoimmune disease, delay is refractory. ITP is based on skin, mucosa hemorrhage, often using multiple location blutpunkte, ecchymosis as clinical manifestation, belongs to the traditional Chinese medical science " bleeding from five sense organs or subcutaneous tissue " " blood trouble " " hair spot " category.Exopathogen attack, accumulate poison in it is interior be induce this disease acute major reason.Exopathogen heat transformed from yang, cult poison and gas Blood is mutually fought, train of thought of burning, blood extravasation, and staying work, then hair is purpura between skin.Cult poison is pented up in interior, and blood rises with fire, above goes out Clear key and be hematemesis；Lower Jiao of heat is moved, yin collaterals is burnt and then just descends blood for two.And the insufficiency of both the spleen and the kindey, have under one's command and have no right；The deficiency of liver-yin and kidney-yin, the fire of deficiency type The main reason for upper inflammation is this disease chronic type.It is insufficiency of the spleen not take the photograph, blood without being united, blood circulating away from normal passage and overflow in seeing purpura outside arteries and veins, Bleeding from five sense organs or subcutaneous tissue, two just bleedings.Burning hot perverse trend consumption impairment of yin, sexual urge internal lesion caused by overexertion, damage liver kidney is Kidney-Yin and phase fire must be prosperous, and cloudy more disappear of hyperactivity of fire and Cause the fire of deficiency type to burn train of thought, compel the absurd row of blood and see bleeding from five sense organs or subcutaneous tissue, purpura, has blood in stool.In short, this disease acute is based on real example, and it is most It is chronic type that case, which starts morbidity, more with the insufficiency of the spleen damage of liver kidney for its pathogenesis basis.And chronic type acute attack is then marked with this void Actually its special bed feature, and clinical common actual situation and deposit.Modern medical therapy is using cortex hormone of aadrenaline as first choice, unsatisfactory curative effect The therapy such as immunodepressant, heavy dose of third pellet impact, splenectomy is then used, makes much to suffer from because of the contraindication of hormone and side effect Person forms Hormone Withdrawal and subtracts syndrome and cannot effect a radical cure.And the toxic side effect of immunodepressant is larger, easily recur, easily lead to after drug withdrawal Bone marrow suppression and the danger of induced tumor and cannot extensive use.Spleen is cut because being a kind of traumatic treatment method entirely, most of Patient is not easily accepted by.
The content of the invention
Present invention aims at providing, a kind of medical expense is low, and Small side effects, curative effect is stablized, and is effectively improved bleeding The production method that tortoise deer gives birth to plate medicine.
Technical scheme：
A kind of production method of tortoise deer life plate medicine, includes the component of following parts by weight：Component A：15-30 parts of radix pseudostellariae, radix astragali 30-60 parts, 15-30 parts of Angelica sinensis, 10-15 parts of arillus longan；B component：15-30 parts of Poria cocos, 15-30 parts of Chinese yam, Rhizoma Atractylodis Macrocephalae 10- 25 parts, 10-30 parts of jujube；Component C：10-15 parts of tortoise-shell glue, 10-15 parts of deer horn glue, 15-30 parts of lotus seeds, Chinese yam rhizome 15- 30 parts, tri- kinds of components of A, B, C are worn into pulvis respectively, after crossing 80-100 mesh sieves, tri- kinds of components of A, B, C are by weight 1:1:1 matches somebody with somebody Than loading capsule.
Preferably, the component of following parts by weight is included：Component A：15 parts of radix pseudostellariae, 30 parts of radix astragali, 15 parts of Angelica sinensis, arillus longan 15 parts；B component：15 parts of Poria cocos, 15 parts of Chinese yam, 15 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of jujube；Component C：15 parts of tortoise-shell glue, 15 parts of deer horn glue, lotus Tri- kinds of components of A, B, C are worn into pulvis, after crossing 80-100 mesh sieves, tri- kinds of components of A, B, C are pressed by sub 30 parts, 15 parts of Chinese yam rhizome respectively Weight ratio 1:1:1 proportioning loads capsule.
The application method of the present invention：The Chinese medicine composition of one capsule 0.5g present invention, once takes 10, takes within one day Twice, a month as a treatment course, takes the 2-4 course for the treatment of.
Good effect in the present invention is as follows：
The present invention takes the photograph blood by QI invigorating righting, invigorating the spleen, tonifying spleen and kidney A, B, C three classes Chinese traditional medicine composition component forms.
Component A：QI invigorating righting, nourishing blood and hemoslasis
It is qi-blood deficiency for immunologic hypofunction.Radix pseudostellariae, radix astragali tonifying Qi, Angelica sinensis, arillus longan green blood, invisible gas energy fast-growing Tangible blood, healthy tendency foot then blood from only, it is all as bleeding can all disappear.
B component：Blood, middle benefit gas hemostasis are taken the photograph in invigorating the spleen
Insufficiency of the spleen blood of taking the photograph is powerless, blood without being united, blood circulating away from normal passage and overflow in seeing various bleedings outside arteries and veins.Poria cocos, Chinese yam, Rhizoma Atractylodis Macrocephalae, Burnt in jujube temperature compensation, strengthening the spleen and replenishing qi, blood has been united, the peaceful network of blood-nourishing, and from only, clinical observation finds there is humoral immunity and cell for bleeding Immune improvement（Anti-platelet autoantibody declines3H-TdR leaching turns to recover normal or improves）
Component C：It is tonifying spleen and kidney, replenishing essence hemostasis
The main bone life marrow of kidney storing essence, essence and blood alternate, the insufficiency of the kidney yang, spleen sun is difficult strong, has under one's command and haves no right, and causes blood metaplasia insufficient, blood is not Follow through.Overflow in outside arteries and veins, ooze out between skin.The insufficiency of the kidney yang, is moved in the fire of deficiency type, upsets ying blood, and blood is dynamic with fire, from through absurd row, and is caused Bleeding.Deer horn glue leads to governor vessel and kidney-replenishing, and tortoise-shell glue leads to conception vessel and tonifying yin is smart, the two is the in love product of flesh and blood, lotus seeds, Chinese yam rhizome Replenish qi to invigorate the spleen, thus warm kidney sun and and invigorating the spleen sun, temperature it is congenital benefit the day after tomorrow be the method searched for the primary cause of disease in treatment.
Tri- kinds of components of medicine A, B, C of the present invention, QI invigorating righting, nourishing blood and hemoslasis can recover immune function, and qi and blood abounding, carries High platelet count, makes bleeding disappear.Replenish qi to invigorate the spleen, middle benefit gas takes the photograph blood, and blood has been united, the peaceful network of blood-nourishing, and bleeding is pacified certainly.It is clinical Observation finds the improvement for having humoral immunity and cellular immunity（Anti-platelet autoantibody declines3H-TdR leaching turns to recover normal or changes It is kind）Tonifying spleen and kidney, replenishing essence hemostasis, adjusts body's immunity, improves spleen, renal function, recover body allomeric function, effectively Improve various bleedings, curative effect is substantially better than Western medicine application cortex hormone of aadrenaline and immunodepressant.
Medicine of the present invention is suitable for Idiopathic Thrombocytopenic Purpura, can effectively improve therapeutic effect, mitigates patient Actual burden, improve the life quality of patient.105 patients were accepted for medical treatment in 3 years by substantial amounts of clinical research, and all cases are equal Meet diagnostic criteria.Curative effect is as follows：Healing 32, effective 61 in 105 patients, invalid 12, total effective rate 88.57%, is controlled 35 ± 10.39 before and after treatment；51±13.47（×109/L）；P ＞ 0.01.
Embodiment
The present invention is described in detail with reference to embodiment：
Embodiment 1：Component A：Radix pseudostellariae 15g, radix astragali 30g, Angelica sinensis 15g, arillus longan 15g；B component：Poria cocos 15g, Chinese yam 15g, Rhizoma Atractylodis Macrocephalae 10g, jujube 15g；Component C：Tortoise-shell glue 10g, deer horn glue 10g, lotus seeds 15g, Chinese yam rhizome 20g.By above-mentioned tri- kinds of groups of A, B, C Divide and wear into pulvis respectively, after crossing 100 mesh sieves, by weight 1:1:1 proportioning loads capsule.
Embodiment 2：Component A：Radix pseudostellariae 30g, radix astragali 60g, Angelica sinensis 30g, arillus longan 15g；B component：Poria cocos 20g, Chinese yam 30g, Rhizoma Atractylodis Macrocephalae 15g, jujube 10g；Component C：Tortoise-shell glue 15g, deer horn glue 15g, lotus seeds 30g, Chinese yam rhizome 15g.By above-mentioned A, B, C tri- Kind component wears into pulvis respectively, after crossing 80 mesh sieves, by weight 1:1:1 proportioning loads capsule.
Embodiment 3：Component A：Radix pseudostellariae 20g, radix astragali 45g, Angelica sinensis 20g, arillus longan 10g；B component：Poria cocos 30g, Chinese yam 30g, Rhizoma Atractylodis Macrocephalae 25g, jujube 30g；Component C：Tortoise-shell glue 15g, deer horn glue 15g, lotus seeds 25g, Chinese yam rhizome 30g.By above-mentioned A, B, C tri- Kind component wears into pulvis respectively, after crossing 90 mesh sieves, by weight 1:1:1 proportioning loads capsule.
Embodiment 4：Component A：Radix pseudostellariae 15g, 30 g of radix astragali, 15 g of Angelica sinensis, 15 g of arillus longan；B component：15 g of Poria cocos, 15 g of Chinese yam, 15 g of Rhizoma Atractylodis Macrocephalae, 15 g of jujube；Component C：15 g of tortoise-shell glue, 15 g of deer horn glue, 30 g of lotus seeds, 15 g of Chinese yam rhizome.Will Above-mentioned tri- kinds of components of A, B, C wear into pulvis respectively, after crossing 90 mesh sieves, by weight 1:1:1 proportioning loads capsule.
The foregoing description of the disclosed embodiments, enables professional and technical personnel in the field to realize or use the present invention. A variety of modifications to these embodiments will be apparent for those skilled in the art, as defined herein General Principle can be realized in other embodiments in the case where not departing from the spirit or scope of patent of the present invention.Therefore, originally Invention is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein Consistent most wide scope.

Claims (2)

1. a kind of production method of tortoise deer life plate medicine, it is characterised in that include the component of following parts by weight：Component A：Radix pseudostellariae 15-30 parts, 30-60 parts of radix astragali, 15-30 parts of Angelica sinensis, 10-15 parts of arillus longan；B component：15-30 parts of Poria cocos, Chinese yam 15- 30 parts, 10-25 parts of Rhizoma Atractylodis Macrocephalae, 10-30 parts of jujube；Component C：10-15 parts of tortoise-shell glue, 10-15 parts of deer horn glue, lotus seeds 15-30 Tri- kinds of components of A, B, C are worn into pulvis, after crossing 80-100 mesh sieves, tri- kinds of components of A, B, C are pressed by part, 15-30 parts of Chinese yam rhizome respectively Weight ratio 1:1:1 proportioning loads capsule.
2. the production method of a kind of tortoise deer life plate medicine according to claim 1, it is characterised in that including following parts by weight Component：Component A：15 parts of radix pseudostellariae, 30 parts of radix astragali, 15 parts of Angelica sinensis, 15 parts of arillus longan；B component：15 parts of Poria cocos, 15 parts of Chinese yam, 15 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of jujube；Component C：15 parts of tortoise-shell glue, 15 parts of deer horn glue, 30 parts of lotus seeds, 15 parts of Chinese yam rhizome, by tri- kinds of A, B, C Component wears into pulvis respectively, and after crossing 80-100 mesh sieves, tri- kinds of components of A, B, C are by weight 1:1:1 proportioning loads capsule.
CN201711432376.XA 2017-12-26 2017-12-26 A kind of production method of tortoise deer life plate medicine Pending CN107929481A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1137393A (en) * 1995-06-08 1996-12-11 孟涛 Yisuishengxue Chinese medicine preparation for tonifying marrow and promoting generation of blood
CN1324647A (en) * 2000-05-18 2001-12-05 王吉光 Prepn. of hematopoietic tortoise-deer capsule
CN105456972A (en) * 2014-09-05 2016-04-06 湖南康寿制药有限公司 Turtle and deer kidney nourishing traditional Chinese medicine composition and preparing method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1137393A (en) * 1995-06-08 1996-12-11 孟涛 Yisuishengxue Chinese medicine preparation for tonifying marrow and promoting generation of blood
CN1324647A (en) * 2000-05-18 2001-12-05 王吉光 Prepn. of hematopoietic tortoise-deer capsule
CN105456972A (en) * 2014-09-05 2016-04-06 湖南康寿制药有限公司 Turtle and deer kidney nourishing traditional Chinese medicine composition and preparing method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
蒋占平等: "《中医药学》", 31 August 2012, 复旦大学出版社 *

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