CN107929192A - A kind of antiallergic sense toothpaste - Google Patents
A kind of antiallergic sense toothpaste Download PDFInfo
- Publication number
- CN107929192A CN107929192A CN201711114707.5A CN201711114707A CN107929192A CN 107929192 A CN107929192 A CN 107929192A CN 201711114707 A CN201711114707 A CN 201711114707A CN 107929192 A CN107929192 A CN 107929192A
- Authority
- CN
- China
- Prior art keywords
- powder
- bone
- parts
- dry
- bone powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of antiallergic sense toothpaste, belong to oral-cavity article technical field.The present invention dries bone, crushes, and sieving, obtains bone powder；Bone powder is stirred with water, is impregnated, is filtered, it is dry, obtain dry bone powder；Dry bone powder is soaked, filtering, must pre-process bone powder with butyl titanate by being stirred；The nitrogen charging insulation of pretreatment bone powder is carbonized, cooling, up to modified charing bone powder；Rubbing agent, wetting agent, adhesive, foaming agent, snail mucus, bagasse powder, Carapax Eriocheir sinensis powder, modified charing bone powder, earthworm dry powder end, phosphatide are placed in batch mixer, high-speed stirred, up to antiallergic sense toothpaste.There is antiallergic sense toothpaste provided by the invention excellent antibacterial tooth-cleaning action and anti-sensitivity of tooth to act on.
Description
Technical field
The invention discloses a kind of antiallergic sense toothpaste, belong to oral-cavity article technical field.
Background technology
Mouth disease is to influence the common disease and frequently-occurring disease of health.Common mouth disease mainly has dental caries, gingivitis, tooth
All diseases, dentine hypersensitivity and canker sore etc..Wherein the crowd with dentin hypersensitiveness is more and more more, is mostly adult,
Crowd's ratio in rural area is higher than the crowd in city.Dentine hypersensitivity, also known as hyperesthesia of dentin, refer to the enamel of dental surface
Abrasion or gingival atrophy cause dentine to expose, and the canaliculi dentales for making to close originally is in open state, cold and hot sour-sweet or mechanical thorn
Swash the dental nerve that can go directly, cause of short duration and sharp pain.This shows harm of the Chronic Non-Communicable Diseases to population health
Property caused the concern of the mankind, the prevention of mouth disease is one of important topic of future life science research.
Most of mouth disease and oral problem, mainly as present in oral cavity caused by pathogenic bacteria.Oral bacteria is taken the photograph
Caused acid can result in decayed tooth after taking sugar；Toxin can cause bleeding gums as caused by oral bacteria；In addition, these are thin
The metabolic waste of bacterium can also result in calculus dentalis and halitosis etc..Therefore, control oral cavity pathogen is to prevent the main of mouth disease to appoint
Business.The most onset concealment of mouth disease, early symptom unobvious, are usually ignored or for " excessive internal heat " etc., other are asked by false judgment
Topic.Moreover, consumer is also weaker to the consciousness of oral health, oral problem do not develop into very serious degree it
Before, it will not generally pay attention to very much, hospital will not be gone to be cured, and may only be the medicine for voluntarily eating of antibiotic or relieving inflammation or internal heat,
With relief of symptoms.If in fact, by good and effective oral cleaning hygienic habit, it can avoid or reduce significantly oral cavity and ask
The generation of topic.And wherein most easy and most straightforward approach is exactly to carry out oral cleaning using toothpaste, remove what is be harmful in oral cavity
Bacterium, and control its regeneration.
Therefore, it is the shortcomings that how improving conventional toothpaste bacteriostasis property and bad anti-sensitive property, comprehensive to obtain higher
The toothpaste of energy, is that it is promoted and applies, meets industrial production demand urgent problem to be solved.
The content of the invention
The present invention solves the technical problem of：The shortcomings that for conventional toothpaste bacteriostasis property and bad anti-sensitive property, carry
A kind of antiallergic sense toothpaste is supplied.
In order to solve the above-mentioned technical problem, the technical solution adopted in the present invention is：
A kind of antiallergic sense toothpaste, includes the raw material of following parts by weight：20~30 parts of rubbing agents, 20~30 parts of wetting agents, 10~
15 parts of adhesives, 5~6 parts of foaming agents, 20~30 parts of snail mucus, 5~6 parts of bagasse powder, 5~6 parts of Carapax Eriocheir sinensis powder, 8
~10 parts of modified charing bone powder, 5~6 parts of earthworm dry powder ends, 10~20 parts of phosphatide；
The preparation process of the modified charing bone powder is：
（1）Bone is dried, is crushed, sieving, obtains bone powder；
（2）By bone powder and water by weight 1：10~1：20 are stirred, and impregnate, filtering, it is dry to moisture content for 10~
20%, obtain dry bone powder；
（3）Will dry bone powder and butyl titanate by weight 1：50~1：100 are stirred, and soak, and filtering, obtains pre- place
Manage bone powder；
（4）The nitrogen charging insulation of pretreatment bone powder is carbonized, cooling, up to modified charing bone powder.
The rubbing agent is calcium carbonate, calcium monohydrogen phosphate, any one or a few in silica.
The wetting agent is glycerine, any one or a few in aliphatic acid or propane diols.
Any one or a few in described adhesive sodium carboxymethylcellulose, xanthans or hydroxyethyl cellulose.
The foaming agent is Tween-60, any one or a few in Tween-80 or Si Pan -80.
The extraction process of the snail mucus is：Water into the wooden frame for fill snail, connect with beaker and flowed out from wooden frame
Snail mucus, up to snail mucus.
The preparation process of the bagasse powder is：Bagasse is dried, obtains drying bagasse；By drying bagasse powder
It is broken, sieving, up to bagasse powder.
The preparation process of the Carapax Eriocheir sinensis powder is：Carapax Eriocheir sinensis are dried, obtain dry Carapax Eriocheir sinensis；Will dry Carapax Eriocheir sinensis powder
It is broken, sieving, up to Carapax Eriocheir sinensis powder.
Step（1）The bone is pig bone, any one or a few in ox bone or chicken bone.
The beneficial effects of the invention are as follows：
（1）The present invention is by adding snail mucus, and in use, first, snail mucus plays the role of buffering, avoids body
Rubbing agent directly contacts enamel and destroys enamel in system, secondly, containing a large amount of amino acid there is emulsification to make in snail mucus
With strengthening the dentifrice performance of toothpaste, again, the glycoprotein in snail mucus has good filming performance, in tooth and gum
Surface forms one layer of water-retaining film, on the one hand, and effectively prevent tooth from drying, bleeding gums and periodontitis, on the other hand, effectively
Cold wind or cold water are avoided, as dental surface hole enters dental pulp, and stimulates dental pulp to cause odonthemodia；
（2）The present invention first, plays good emulsification in system, strengthens the dentifrice performance of toothpaste by adding phosphatide,
Secondly, phosphatide is negatively charged so that snail mucus and the combination power of phosphatide strengthen, and secondly, negative electrical charge phospholipid composition occupies snail
The position of part functional group in ox mucus skeleton, reduces the oscillation intensity of covalent bond in snail mucus molecule, meanwhile, in film
The free hydroxyl that hydrophilic bond can be formed with water rolls into a ball reduction, and the water content of film reduces, so that the mechanical performance of protective film obtains
To lifting, protective effect of the protective film to tooth and gum is further enhanced, in addition, phosphatide hydrolyzes in alkaline conditions, can be inhaled
Draw the calcium ion in system, after making its hydrolysate absorption calcium ion, nutriment can be used as, promote enamel regeneration, enhancing
The consistency of dental surface adamantine layer, plays the role of tooth-whitening, and can effectively avoid cold wind or cold water, with tooth
Tooth surface hole enters dental pulp, and stimulates dental pulp to cause odonthemodia；
（3）The present invention is by adding modified charing bone powder, on the one hand, modified charing bone powder can be used as rubbing agent, rise
To good tooth-cleaning action, on the other hand, charing bone powder has certain absorption property, and the mould being harmful in oral cavity is inhaled
It is attached into charing bone powder, carbonize bone powder in titanium dioxide play fine sterilization functions, so as to enhance killing for toothpaste
Bacterium performance；
（4）The present invention by add earthworm dry powder end, on the one hand, bristle can assist toothbrush in earthworm dry powder end, by bristles without
Tartar is removed with swill inside the deep teeth crevice of method, further enhances the tooth-cleaning action of toothpaste, on the other hand, earthworm
Dry powder has heat-clearing, the relieving convulsion and effect of Dingchuan.
Embodiment
Water into the wooden frame for fill snail, the snail mucus flowed out from wooden frame is connect with No. 1 beaker, is glued up to snail
Liquid；Bagasse is placed in baking oven, dry 1~2h, obtains drying bagasse；Drying bagasse is placed in pulverizer and is crushed, mistake
The sieve of 100~120 mesh, up to bagasse powder；Carapax Eriocheir sinensis are placed in baking oven, dry 1~2h, obtains dry Carapax Eriocheir sinensis；Will be dry
Dry Carapax Eriocheir sinensis, which are placed in pulverizer, to be crushed, and the sieve of 80~100 mesh is crossed, up to Carapax Eriocheir sinensis powder；Bone is placed in baking oven, it is dry
1~2h, obtains drying bone, then drying bone is placed in ball mill, under the conditions of rotating speed is 500~600r/min, ball milling powder
Broken 40~60min, crosses the sieve of 100~120 mesh, obtains bone powder；By bone powder and water by weight 1：10~1：20 are placed in 2
In number beaker, under the conditions of rotating speed is 300~400r/min, 40~60min of dipping is stirred, obtains maceration extract, then will leaching
Stain liquid filters, and obtains filter cake, then by filtration cakes torrefaction to moisture content is 10~20%, obtains dry bone powder；Will dry bone powder with
Butyl titanate is by weight 1：50~1：100 are placed in single-necked flask, under the conditions of rotating speed is 500~600r/min, stirring
Mixing 1~2h of immersion, obtains soak, then soak is filtered, and must pre-process bone powder；Pretreatment bone powder is placed in charcoal
Change in stove, and nitrogen be passed through into stove with 60~90mL/min speed, in temperature be 550~650 DEG C, under nitrogen protective condition,
Insulation 2~3h of charing, room temperature is down to stove, up to modified charing bone powder；Count in parts by weight, by 20~30 parts of frictions
Agent, 20~30 parts of wetting agents, 10~15 parts of adhesives, 5~6 parts of foaming agents, 20~30 parts of snail mucus, 5~6 parts of bagasse powders
End, 5~6 parts of Carapax Eriocheir sinensis powder, 8~10 parts of modified charing bone powder, 5~6 parts of earthworm dry powder ends, 10~20 parts of phosphatide are placed in
In batch mixer, under the conditions of rotating speed is 1000~1200r/min, high-speed stirred mixes 40~60min, up to antiallergic sense toothpaste.
The rubbing agent is calcium carbonate, calcium monohydrogen phosphate, any one or a few in silica.The wetting agent is glycerine, fat
Acid or propane diols in any one or a few.In described adhesive sodium carboxymethylcellulose, xanthans or hydroxyethyl cellulose
Any one or a few.The foaming agent is Tween-60, any one or a few in Tween-80 or Si Pan -80.It is described
Bone is pig bone, any one or a few in ox bone or chicken bone.
Example 1
Water into the wooden frame for fill snail, the snail mucus flowed out from wooden frame is connect with No. 1 beaker, up to snail mucus；Will
Bagasse is placed in baking oven, and dry 2h, obtains drying bagasse；Drying bagasse is placed in pulverizer and is crushed, crosses 120 purposes
Sieve, up to bagasse powder；Carapax Eriocheir sinensis are placed in baking oven, dry 2h, obtains dry Carapax Eriocheir sinensis；Dry Carapax Eriocheir sinensis are placed in crushing
Crushed in machine, the sieve of 100 mesh is crossed, up to Carapax Eriocheir sinensis powder；Bone is placed in baking oven, dry 2h, obtains drying bone, then will dry
Dry bone is placed in ball mill, and under the conditions of rotating speed is 600r/min, ball mill grinding 60min, crosses the sieve of 120 mesh, obtain bone powder
End；By bone powder and water by weight 1：20 are placed in No. 2 beakers, under the conditions of rotating speed is 400r/min, are stirred leaching
Stain 60min, obtains maceration extract, then filters maceration extract, obtains filter cake, then by filtration cakes torrefaction to moisture content is 20%, obtains dry bone
Powder；Will dry bone powder and butyl titanate by weight 1：100 are placed in single-necked flask, in rotating speed be 600r/min bars
Under part, immersion 2h is stirred, obtains soak, then soak is filtered, bone powder must be pre-processed；Bone powder will be pre-processed
It is placed in retort, and nitrogen is passed through into stove with 90mL/min speed, is 650 DEG C in temperature, under nitrogen protective condition, keeps the temperature
3h is carbonized, room temperature is down to stove, up to modified charing bone powder；Count in parts by weight, by 30 parts of rubbing agents, 30 parts of wettings
Agent, 15 parts of adhesives, 6 parts of foaming agents, 30 parts of snail mucus, 6 parts of bagasse powder, 6 parts of Carapax Eriocheir sinensis powder, 10 parts of modified charings
Bone powder, 6 parts of earthworm dry powder ends, 20 parts of phosphatide are placed in batch mixer, under the conditions of rotating speed is 1200r/min, high-speed stirred
60min is mixed, up to antiallergic sense toothpaste.The rubbing agent is calcium carbonate.The wetting agent is glycerine.Described adhesive carboxymethyl
Sodium cellulosate.The foaming agent is Tween-60.The bone is pig bone.
Example 2
Bagasse is placed in baking oven, dry 2h, obtains drying bagasse；Drying bagasse is placed in pulverizer and is crushed, crosses 120
Purpose is sieved, up to bagasse powder；Carapax Eriocheir sinensis are placed in baking oven, dry 2h, obtains dry Carapax Eriocheir sinensis；Dry Carapax Eriocheir sinensis are placed in
Crushed in pulverizer, the sieve of 100 mesh is crossed, up to Carapax Eriocheir sinensis powder；Bone is placed in baking oven, dry 2h, obtains drying bone, then
Drying bone is placed in ball mill, under the conditions of rotating speed is 600r/min, ball mill grinding 60min, crosses the sieve of 120 mesh, obtain bone
Head powder；By bone powder and water by weight 1：20 are placed in No. 2 beakers, and under the conditions of rotating speed is 400r/min, stirring is mixed
Dipping 60min is closed, maceration extract is obtained, then filters maceration extract, obtain filter cake, then by filtration cakes torrefaction to moisture content is 20%, obtains drying
Bone powder；Will dry bone powder and butyl titanate by weight 1：100 are placed in single-necked flask, in rotating speed be 600r/
Under the conditions of min, immersion 2h is stirred, obtains soak, then soak is filtered, bone powder must be pre-processed；Bone will be pre-processed
Head powder is placed in retort, and nitrogen is passed through into stove with 90mL/min speed, in temperature be 650 DEG C, nitrogen protective condition
Under, insulation charing 3h, room temperature is down to stove, up to modified charing bone powder；Count in parts by weight, by 30 parts of rubbing agents, 30
Part wetting agent, 15 parts of adhesives, 6 parts of foaming agents, 6 parts of bagasse powder, 6 parts of Carapax Eriocheir sinensis powder, 10 parts of modified charing bone powder
End, 6 parts of earthworm dry powder ends, 20 parts of phosphatide are placed in batch mixer, under the conditions of rotating speed is 1200r/min, high-speed stirred mixing
60min, up to antiallergic sense toothpaste.The rubbing agent is calcium carbonate.The wetting agent is glycerine.Described adhesive carboxymethyl cellulose
Plain sodium.The foaming agent is Tween-60.The bone is pig bone.
Example 3
Water into the wooden frame for fill snail, the snail mucus flowed out from wooden frame is connect with No. 1 beaker, up to snail mucus；Will
Bagasse is placed in baking oven, and dry 2h, obtains drying bagasse；Drying bagasse is placed in pulverizer and is crushed, crosses 120 purposes
Sieve, up to bagasse powder；Carapax Eriocheir sinensis are placed in baking oven, dry 2h, obtains dry Carapax Eriocheir sinensis；Dry Carapax Eriocheir sinensis are placed in crushing
Crushed in machine, the sieve of 100 mesh is crossed, up to Carapax Eriocheir sinensis powder；Bone is placed in baking oven, dry 2h, obtains drying bone, then will dry
Dry bone is placed in ball mill, and under the conditions of rotating speed is 600r/min, ball mill grinding 60min, crosses the sieve of 120 mesh, obtain bone powder
End；By bone powder and water by weight 1：20 are placed in No. 2 beakers, under the conditions of rotating speed is 400r/min, are stirred leaching
Stain 60min, obtains maceration extract, then filters maceration extract, obtains filter cake, then by filtration cakes torrefaction to moisture content is 20%, obtains dry bone
Powder；Will dry bone powder and butyl titanate by weight 1：100 are placed in single-necked flask, in rotating speed be 600r/min bars
Under part, immersion 2h is stirred, obtains soak, then soak is filtered, bone powder must be pre-processed；Bone powder will be pre-processed
It is placed in retort, and nitrogen is passed through into stove with 90mL/min speed, is 650 DEG C in temperature, under nitrogen protective condition, keeps the temperature
3h is carbonized, room temperature is down to stove, up to modified charing bone powder；Count in parts by weight, by 30 parts of rubbing agents, 30 parts of wettings
Agent, 15 parts of adhesives, 6 parts of foaming agents, 30 parts of snail mucus, 6 parts of bagasse powder, 6 parts of Carapax Eriocheir sinensis powder, 10 parts of modified charings
Bone powder, 6 parts of earthworm dry powder ends are placed in batch mixer, under the conditions of rotating speed is 1200r/min, high-speed stirred mixing 60min,
Up to antiallergic sense toothpaste.The rubbing agent is calcium carbonate.The wetting agent is glycerine.Described adhesive sodium carboxymethylcellulose.
The foaming agent is Tween-60.The bone is pig bone.
Example 4
Water into the wooden frame for fill snail, the snail mucus flowed out from wooden frame is connect with No. 1 beaker, up to snail mucus；Will
Bagasse is placed in baking oven, and dry 2h, obtains drying bagasse；Drying bagasse is placed in pulverizer and is crushed, crosses 120 purposes
Sieve, up to bagasse powder；Carapax Eriocheir sinensis are placed in baking oven, dry 2h, obtains dry Carapax Eriocheir sinensis；Dry Carapax Eriocheir sinensis are placed in crushing
Crushed in machine, the sieve of 100 mesh is crossed, up to Carapax Eriocheir sinensis powder；Count in parts by weight, by 30 parts of rubbing agents, 30 parts of wetting agents, 15 parts
Adhesive, 6 parts of foaming agents, 30 parts of snail mucus, 6 parts of bagasse powder, 6 parts of Carapax Eriocheir sinensis powder, 6 parts of earthworm dry powder ends, 20 parts
Phosphatide is placed in batch mixer, under the conditions of rotating speed is 1200r/min, high-speed stirred mixing 60min, up to antiallergic sense toothpaste.Institute
It is calcium carbonate to state rubbing agent.The wetting agent is glycerine.Described adhesive sodium carboxymethylcellulose.The foaming agent for tween-
60.The bone is pig bone.
Example 5
Water into the wooden frame for fill snail, the snail mucus flowed out from wooden frame is connect with No. 1 beaker, up to snail mucus；Will
Bagasse is placed in baking oven, and dry 2h, obtains drying bagasse；Drying bagasse is placed in pulverizer and is crushed, crosses 120 purposes
Sieve, up to bagasse powder；Carapax Eriocheir sinensis are placed in baking oven, dry 2h, obtains dry Carapax Eriocheir sinensis；Dry Carapax Eriocheir sinensis are placed in crushing
Crushed in machine, the sieve of 100 mesh is crossed, up to Carapax Eriocheir sinensis powder；Bone is placed in baking oven, dry 2h, obtains drying bone, then will dry
Dry bone is placed in ball mill, and under the conditions of rotating speed is 600r/min, ball mill grinding 60min, crosses the sieve of 120 mesh, obtain bone powder
End；By bone powder and water by weight 1：20 are placed in No. 2 beakers, under the conditions of rotating speed is 400r/min, are stirred leaching
Stain 60min, obtains maceration extract, then filters maceration extract, obtains filter cake, then by filtration cakes torrefaction to moisture content is 20%, obtains dry bone
Powder；Will dry bone powder and butyl titanate by weight 1：100 are placed in single-necked flask, in rotating speed be 600r/min bars
Under part, immersion 2h is stirred, obtains soak, then soak is filtered, bone powder must be pre-processed；Bone powder will be pre-processed
It is placed in retort, and nitrogen is passed through into stove with 90mL/min speed, is 650 DEG C in temperature, under nitrogen protective condition, keeps the temperature
3h is carbonized, room temperature is down to stove, up to modified charing bone powder；Count in parts by weight, by 30 parts of rubbing agents, 30 parts of wettings
Agent, 15 parts of adhesives, 6 parts of foaming agents, 30 parts of snail mucus, 6 parts of bagasse powder, 6 parts of Carapax Eriocheir sinensis powder, 10 parts of modified charings
Bone powder, 20 parts of phosphatide are placed in batch mixer, under the conditions of rotating speed is 1200r/min, high-speed stirred mixing 60min, to obtain the final product
Antiallergic sense toothpaste.The rubbing agent is calcium carbonate.The wetting agent is glycerine.Described adhesive sodium carboxymethylcellulose.It is described
Foaming agent is Tween-60.The bone is pig bone.
Comparative example：The antiallergic sense toothpaste of Guangzhou toothpaste Co., Ltd production.
The antiallergic sense toothpaste of the gained of example 1 to 5 and comparative example product are subjected to performance detection, specific detection method is as follows：
1. anti-tooth sensitivity：Sensitivity of tooth subject, every group of 5 people are chosen according to WS/T326.4, detection uses test specimen toothpaste 8
Zhou Qianhou tooth sensitivities, and be averaged as end value；Using the air gun of dental unit in distance sensitive tooth
Blow and spray 1s at 1cm, air compressor machine pressure is 60psi (± 5psi), and blow air temperature is 19~21 DEG C, and when air blowing places a finger on adjacent teeth
To avoid the accuracy for influencing result；Evaluated with Schiff cold airs Sensitivity Index, score is as follows：
0=tooth and subject do not react air stimulation；
1=tooth and subject have air stimulation reaction, but do not ask to stop to stimulate；
2=tooth and subject have air stimulation reaction, and request, which stops to stimulate or removes, to stimulate；
3=tooth and subject have air stimulation reaction, and stimulation causes pain, and request stops.
The low score mark sensitiveness of the parameter is reduced；
2. bacteriostasis property：The preparation of bacteria inhibition tablet：After being diluted to homogeneous toothpaste slurry using toothpaste and water 1: 3, take sterile and drying
Filter paper；Every dropwise addition 20 μ L of toothpaste, then lies against filter paper in clean sterilized petri dishes, uncaps to put in 37 DEG C of incubator and bakes
It is dry, or put spontaneously dry at room temperature after it is spare；Reference《Disinfection technology standard（Version in 2002）》Resisted（Suppression）Bacterium is tested and selects
The uniformly antibacterial ring size progress inhibition zone diameter measurement of integral asepsis growth, measuring its diameter should be using antibacterial ring size outer as boundary；Suppression
Collarium diameter is bigger, then fungistatic effect is better.
Specific testing result is as shown in table 1：
Table 1
From 1 testing result of table, antiallergic sense toothpaste prepared by technical solution of the present invention have excellent antibacterial dentifrice performance and
The characteristics of anti-tooth sensitivity, use in oral cleaning.
Claims (9)
- A kind of 1. antiallergic sense toothpaste, it is characterised in that：Include the raw material of following parts by weight：20~30 parts of rubbing agents, 20~30 Part wetting agent, 10~15 parts of adhesives, 5~6 parts of foaming agents, 20~30 parts of snail mucus, 5~6 parts of bagasse powder, 5~6 parts Carapax Eriocheir sinensis powder, 8~10 parts of modified charing bone powder, 5~6 parts of earthworm dry powder ends, 10~20 parts of phosphatide；The preparation process of the modified charing bone powder is：（1）Bone is dried, is crushed, sieving, obtains bone powder；（2）By bone powder and water by weight 1：10~1：20 are stirred, and impregnate, filtering, it is dry to moisture content for 10~ 20%, obtain dry bone powder；（3）Will dry bone powder and butyl titanate by weight 1：50~1：100 are stirred, and soak, and filtering, obtains pre- place Manage bone powder；（4）The nitrogen charging insulation of pretreatment bone powder is carbonized, cooling, up to modified charing bone powder.
- A kind of 2. antiallergic sense toothpaste according to claim 1, it is characterised in that：The rubbing agent is calcium carbonate, calcium monohydrogen phosphate, Any one or a few in silica.
- A kind of 3. antiallergic sense toothpaste according to claim 1, it is characterised in that：The wetting agent is glycerine, aliphatic acid or third Any one or a few in glycol.
- A kind of 4. antiallergic sense toothpaste according to claim 1, it is characterised in that：Described adhesive sodium carboxymethylcellulose, it is yellow Any one or a few in virgin rubber or hydroxyethyl cellulose.
- A kind of 5. antiallergic sense toothpaste according to claim 1, it is characterised in that：The foaming agent is Tween-60, Tween-80 Or any one or a few in Si Pan -80.
- A kind of 6. antiallergic sense toothpaste according to claim 1, it is characterised in that：The extraction process of the snail mucus is：To Watering in the wooden frame of snail is filled, the snail mucus flowed out from wooden frame is connect with beaker, up to snail mucus.
- A kind of 7. antiallergic sense toothpaste according to claim 1, it is characterised in that：The preparation process of the bagasse powder is： Bagasse is dried, obtains drying bagasse；Drying bagasse is crushed, is sieved, up to bagasse powder.
- A kind of 8. antiallergic sense toothpaste according to claim 1, it is characterised in that：The preparation process of the Carapax Eriocheir sinensis powder is： Carapax Eriocheir sinensis are dried, obtain dry Carapax Eriocheir sinensis；Dry Carapax Eriocheir sinensis are crushed, sieving, up to Carapax Eriocheir sinensis powder.
- A kind of 9. antiallergic sense toothpaste according to claim 1, it is characterised in that：Step（1）The bone is pig bone, ox bone or Any one or a few in chicken bone.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711114707.5A CN107929192A (en) | 2017-11-13 | 2017-11-13 | A kind of antiallergic sense toothpaste |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711114707.5A CN107929192A (en) | 2017-11-13 | 2017-11-13 | A kind of antiallergic sense toothpaste |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107929192A true CN107929192A (en) | 2018-04-20 |
Family
ID=61933916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711114707.5A Pending CN107929192A (en) | 2017-11-13 | 2017-11-13 | A kind of antiallergic sense toothpaste |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107929192A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114796064A (en) * | 2022-06-06 | 2022-07-29 | 云南白药集团健康产品有限公司 | Bagasse phosphate calcium composite material and preparation method and application thereof |
| CN114903804A (en) * | 2022-06-06 | 2022-08-16 | 云南白药集团健康产品有限公司 | Bagasse/calcium carbonate composite material and preparation method and application thereof |
| CN115040454A (en) * | 2022-06-06 | 2022-09-13 | 云南白药集团健康产品有限公司 | Elastic bagasse and preparation method and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1079645A (en) * | 1993-05-20 | 1993-12-22 | 程宝义 | Edible toothpaste for children |
| CN101023914A (en) * | 2007-03-23 | 2007-08-29 | 昆明牙膏有限责任公司 | Toothpaste containing notoginseng extract and preparing method |
| CN101690706A (en) * | 2009-09-22 | 2010-04-07 | 河南省济源市济世药业有限公司 | Chinese medicinal toothpaste and preparation method thereof |
| CN104414954A (en) * | 2013-08-28 | 2015-03-18 | 青岛医防消毒专业技术中心 | Snail skin cream for relieving allergy |
-
2017
- 2017-11-13 CN CN201711114707.5A patent/CN107929192A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1079645A (en) * | 1993-05-20 | 1993-12-22 | 程宝义 | Edible toothpaste for children |
| CN101023914A (en) * | 2007-03-23 | 2007-08-29 | 昆明牙膏有限责任公司 | Toothpaste containing notoginseng extract and preparing method |
| CN101690706A (en) * | 2009-09-22 | 2010-04-07 | 河南省济源市济世药业有限公司 | Chinese medicinal toothpaste and preparation method thereof |
| CN104414954A (en) * | 2013-08-28 | 2015-03-18 | 青岛医防消毒专业技术中心 | Snail skin cream for relieving allergy |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114796064A (en) * | 2022-06-06 | 2022-07-29 | 云南白药集团健康产品有限公司 | Bagasse phosphate calcium composite material and preparation method and application thereof |
| CN114903804A (en) * | 2022-06-06 | 2022-08-16 | 云南白药集团健康产品有限公司 | Bagasse/calcium carbonate composite material and preparation method and application thereof |
| CN115040454A (en) * | 2022-06-06 | 2022-09-13 | 云南白药集团健康产品有限公司 | Elastic bagasse and preparation method and application thereof |
| CN114796064B (en) * | 2022-06-06 | 2023-07-18 | 云南白药集团健康产品有限公司 | Bagasse calcium phosphate composite material, and preparation method and application thereof |
| CN114903804B (en) * | 2022-06-06 | 2023-08-08 | 云南白药集团健康产品有限公司 | Bagasse/calcium carbonate composite material, and preparation method and application thereof |
| CN115040454B (en) * | 2022-06-06 | 2024-04-05 | 云南白药集团健康产品有限公司 | Elastic bagasse and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104244912B (en) | Have and alleviate oral cavity pain and kill oral cavity bacterium and the natural antibacterial dentifrice composition of stable neural effect | |
| CN107929192A (en) | A kind of antiallergic sense toothpaste | |
| CN106580866B (en) | Children's toothpaste | |
| CN110051559A (en) | Alginates dentifrice composition and preparation method thereof | |
| CN107184403A (en) | A kind of toothpaste and preparation method thereof | |
| CN1294895C (en) | Natural and whitening tooth powder and production thereof | |
| CN102512337B (en) | Night toothpaste and morning and night combination toothpaste | |
| CN103446003A (en) | Alga hydrating mask and preparation method thereof | |
| KR102376424B1 (en) | Abrasive composition for pet toothpaste comprising enzyme treated pear ground and pet toothpaste comprising the same | |
| CN113908067A (en) | Composition for resisting tooth sensitivity, preparation method and application thereof, and oral care product containing composition | |
| CN107468631A (en) | Fish scale collagen biological toothpaste | |
| CN107307579A (en) | Degradable chitosan toothbrush of automatically cleaning and preparation method thereof | |
| CN102342905A (en) | Toothpaste | |
| CN105902407A (en) | Lysozyme hydrochloride toothpaste and preparation method thereof | |
| CN108524418A (en) | A kind of natural antiscale whitening toothpaste and preparation method thereof | |
| KR20140023081A (en) | Toothpaste composition containing stone cell and toothpaste prepared therefrom | |
| CN112494349A (en) | Oral care composition with anti-sensitivity, gum repairing and antibacterial effects | |
| CN103599182A (en) | Traditional Chinese medicine composition and preparation method thereof, and oral cavity cleaning and nursing product and preparation method thereof | |
| CN105287244A (en) | Montmorillonite-containing functional toothpaste and preparation method thereof | |
| CN105213216B (en) | A kind of natural disaccharide antibacterial shield tooth gargle and preparation method thereof | |
| CN108969457A (en) | The toothpaste and preparation method thereof of anti-treating dental ulcer | |
| CN100539992C (en) | Unevenness false tooth detergent | |
| CN110302067A (en) | A kind of adjuvant and preparation method thereof having tooth whitening and repair function | |
| CN102641222A (en) | Tooth and oral cavity cleaning composite and cleaning method | |
| CN107375123A (en) | A kind of alkalescent Chinese herbal medicine false-tooth cleaning plate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20180426 Address after: 213000 Room 502, unit 54, Lihua three village, Tianning District, Changzhou, Jiangsu, China Applicant after: Zhou Rong Address before: 213102 Changzhou, Jiangsu Tianning District, Li Hua three village 61 Ding unit 102 room Applicant before: CHANGZHOU KAIHENG TEXTILE Co.,Ltd. |
|
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180420 |